8010:rps12
gene id: 8010:rps12
uniprot id: A0A3P8XJV8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8010:eif4ebp2
gene id: 8010:eif4ebp2
uniprot id: A0A6Q2YAK5
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8010:itgb6
gene id: 8010:itgb6
uniprot id: A0A3P8YSW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8010:gja8b
gene id: 8010:gja8b
uniprot id: A0A3P9AHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:slitrk6
gene id: 8010:slitrk6
uniprot id: A0A6Q2X977
names: Similarity
messages: Belongs to the SLITRK family.

8010:evx2
gene id: 8010:evx2
uniprot id: A0A3P8Z695
names: Subcellular Location Annotation
messages: Nucleus

8010:prrx1b
gene id: 8010:prrx1b
uniprot id: A0A3P9AI58
uniprot id: W5VPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8010:LOC105028432
gene id: 8010:LOC105028432
uniprot id: A0A3P9AL54
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:tmem39b
gene id: 8010:tmem39b
uniprot id: A0A3P8XG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8010:lipt1
gene id: 8010:lipt1
uniprot id: A0A3P8ZK27
names: Similarity
messages: Belongs to the LplA family.

8010:cbr1l
gene id: 8010:cbr1l
uniprot id: A0A3P8YYW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:ccn2a
gene id: 8010:ccn2a
uniprot id: A0A3P9AEY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC114828637
gene id: 8010:LOC114828637
uniprot id: A0A3P8YR38
names: Similarity
messages: Belongs to the MHC class I family.

8010:creg2
gene id: 8010:creg2
uniprot id: A0A3P9AGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8010:parvb
gene id: 8010:parvb
uniprot id: A0A3P8XTT8
uniprot id: A0A3P8XU01
uniprot id: A0A3P8ZRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8010:eda2r
gene id: 8010:eda2r
uniprot id: A0A3P8Y0U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:zgc:198371
gene id: 8010:zgc:198371
uniprot id: A0A3P9AMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:plekho1b
gene id: 8010:plekho1b
uniprot id: A0A3P8ZGB9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:fgf24
gene id: 8010:fgf24
uniprot id: A0A3P8Z330
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:LOC105016335
gene id: 8010:LOC105016335
uniprot id: A0A3P8ZSY3
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8010:abcc2
gene id: 8010:abcc2
uniprot id: A0A3P8ZXL4
uniprot id: A0A3P8ZYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8010:mnx2a
gene id: 8010:mnx2a
uniprot id: A0A3P8Y7X1
names: Subcellular Location Annotation
messages: Nucleus

8010:tpm1
gene id: 8010:tpm1
uniprot id: A0A3P8YQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8010:LOC105007462
gene id: 8010:LOC105007462
uniprot id: A0A3P8ZDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:itpka
gene id: 8010:itpka
uniprot id: A0A3P8XAU0
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:zfhx2
gene id: 8010:zfhx2
uniprot id: A0A6Q2ZMX9
names: Subcellular Location Annotation
messages: Nucleus

8010:fam207a
gene id: 8010:fam207a
uniprot id: A0A3P9A8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

8010:LOC105019316
gene id: 8010:LOC105019316
uniprot id: A0A3P8YWS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8010:ptges3b
gene id: 8010:ptges3b
uniprot id: A0A3P8YGD6
names: Similarity
messages: Belongs to the p23/wos2 family.

8010:adora1b
gene id: 8010:adora1b
uniprot id: A0A3P9A2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8010:cdc73
gene id: 8010:cdc73
uniprot id: A0A3P8ZGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

8010:naa35
gene id: 8010:naa35
uniprot id: A0A3P8XCA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

8010:kcna1b
gene id: 8010:kcna1b
uniprot id: A0A3P8Y1E2
names: Subcellular Location Annotation
messages: Membrane

8010:pleca
gene id: 8010:pleca
uniprot id: A0A3P9ABW7
uniprot id: A0A3P9ACQ9
uniprot id: A0A3P9ACW6
names: Subcellular Location Annotation
messages: cytoskeleton

8010:mcl1b
gene id: 8010:mcl1b
uniprot id: A0A3P8Y1W8
uniprot id: A0A3P8ZWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

8010:slc4a1b
gene id: 8010:slc4a1b
uniprot id: A0A3P8X9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8010:gstt1a
gene id: 8010:gstt1a
uniprot id: A0A3P8ZCG3
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8010:tmem242
gene id: 8010:tmem242
uniprot id: A0A6Q2Z1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

8010:LOC105010633
gene id: 8010:LOC105010633
uniprot id: A0A3P8Y522
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

8010:LOC105016854
gene id: 8010:LOC105016854
uniprot id: A0A3P8XRL9
uniprot id: A0A6Q2ZLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

8010:kdelr3
gene id: 8010:kdelr3
uniprot id: A0A3P8XVW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:denr
gene id: 8010:denr
uniprot id: A0A3P8XDL0
uniprot id: C1BYU6
names: Similarity
messages: Belongs to the DENR family.

8010:foxb2
gene id: 8010:foxb2
uniprot id: A0A3P8XC15
names: Subcellular Location Annotation
messages: Nucleus

8010:rad23b
gene id: 8010:rad23b
uniprot id: A0A3P8XR80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8010:lyrm4
gene id: 8010:lyrm4
uniprot id: C1BX30
names: Similarity
messages: Belongs to the complex I LYR family.

8010:ckmt1
gene id: 8010:ckmt1
uniprot id: A0A3P8XFB8
uniprot id: A0A6Q2XBA0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8010:hint3
gene id: 8010:hint3
uniprot id: A0A3P8XHJ1
names: Similarity
messages: Belongs to the HINT family.

8010:tmco4
gene id: 8010:tmco4
uniprot id: A0A3P8YHX8
names: Similarity
messages: Belongs to the TMCO4 family.

8010:mettl8
gene id: 8010:mettl8
uniprot id: A0A3P8Z292
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8010:supt6h
gene id: 8010:supt6h
uniprot id: A0A6Q2Z111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

8010:kcnj9
gene id: 8010:kcnj9
uniprot id: A0A3P8Y4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:LOC105012645
gene id: 8010:LOC105012645
uniprot id: C1BXT8
names: Similarity
messages: Belongs to the stathmin family.

8010:gnb1a
gene id: 8010:gnb1a
uniprot id: A0A3P8YMV7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

f3
gene id: 8010:il17a/f3
uniprot id: A0A3P8XVC9
names: Similarity
messages: Belongs to the IL-17 family.

8010:LOC105016286
gene id: 8010:LOC105016286
uniprot id: A0A3P8ZKU2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:orc5
gene id: 8010:orc5
uniprot id: A0A3P8X8D7
names: Subcellular Location Annotation
messages: Nucleus

8010:tfcp2l1
gene id: 8010:tfcp2l1
uniprot id: A0A3P8XR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8010:mdh1b
gene id: 8010:mdh1b
uniprot id: A0A3P8Z1J4
uniprot id: A0A3P8Z3C3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8010:cops7a
gene id: 8010:cops7a
uniprot id: A0A3P8YX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

8010:kat8
gene id: 8010:kat8
uniprot id: A0A3P9AMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8010:edc3
gene id: 8010:edc3
uniprot id: A0A3P8ZKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

8010:LOC105030356
gene id: 8010:LOC105030356
uniprot id: A0A3P8Y9I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8010:mtmr7b
gene id: 8010:mtmr7b
uniprot id: A0A3P8YNE0
uniprot id: A0A3P9AB92
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8010:LOC105028205
gene id: 8010:LOC105028205
uniprot id: A0A3P8XXA0
uniprot id: A0A3P8Y0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

8010:kcnj8
gene id: 8010:kcnj8
uniprot id: A0A3P8Z120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:ccn4a
gene id: 8010:ccn4a
uniprot id: A0A3P9AJX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:hoxc9a
gene id: 8010:hoxc9a
uniprot id: A0A3P8ZNK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:LOC105007368
gene id: 8010:LOC105007368
uniprot id: A0A3P8XGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8010:LOC105030459
gene id: 8010:LOC105030459
uniprot id: A0A3P8ZJ77
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

8010:guk1a
gene id: 8010:guk1a
uniprot id: A0A3P9AKM4
names: Similarity
messages: Belongs to the guanylate kinase family.

8010:metap1
gene id: 8010:metap1
uniprot id: A0A3P8YB40
uniprot id: A0A3P8YBA5
uniprot id: A0A6Q2YIX0
uniprot id: A0A6Q2Z4F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8010:nfic
gene id: 8010:nfic
uniprot id: A0A3P8YCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8010:dlgap5
gene id: 8010:dlgap5
uniprot id: A0A3P8YPC7
names: Similarity
messages: Belongs to the SAPAP family.

8010:efnb2a
gene id: 8010:efnb2a
uniprot id: A0A3P8YEI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:fech
gene id: 8010:fech
uniprot id: A0A3P8YFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

8010:sptlc3
gene id: 8010:sptlc3
uniprot id: A0A3P8YLU9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8010:ptger1b
gene id: 8010:ptger1b
uniprot id: A0A3P8Y275
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:tmem254
gene id: 8010:tmem254
uniprot id: C1BYM6
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105030878
gene id: 8010:LOC105030878
uniprot id: A0A3P8XJL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:cops2
gene id: 8010:cops2
uniprot id: A0A3P8XKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

8010:bms1
gene id: 8010:bms1
uniprot id: A0A3P8X777
names: Subcellular Location Annotation
messages: nucleolus

8010:copb1
gene id: 8010:copb1
uniprot id: A0A3P8XTZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8010:hnf4a
gene id: 8010:hnf4a
uniprot id: A0A3P8ZLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:LOC105009424
gene id: 8010:LOC105009424
uniprot id: A0A3P9A5D3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:LOC105021566
gene id: 8010:LOC105021566
uniprot id: A0A3P9A303
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105019513
gene id: 8010:LOC105019513
uniprot id: A0A3P8YVT5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8010:ralaa
gene id: 8010:ralaa
uniprot id: A0A6Q2XFV9
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8010:c12h1orf174
gene id: 8010:c12h1orf174
uniprot id: A0A3P9A956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8010:nppb
gene id: 8010:nppb
uniprot id: C1BXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8010:ddah2
gene id: 8010:ddah2
uniprot id: A0A3P8ZPU9
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8010:si:dkey-88i8.2
gene id: 8010:si:dkey-88i8.2
uniprot id: A0A3P9A9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8010:mvb12ba
gene id: 8010:mvb12ba
uniprot id: A0A6Q2WW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8010:cavin1a
gene id: 8010:cavin1a
uniprot id: A0A6Q2XVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8010:gcfc2
gene id: 8010:gcfc2
uniprot id: A0A3P8YPW0
names: Similarity
messages: Belongs to the GCF family.

8010:LOC105020008
gene id: 8010:LOC105020008
uniprot id: A0A3P8Z2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8010:pdgfra
gene id: 8010:pdgfra
uniprot id: A0A3P8XJ92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:mdm4
gene id: 8010:mdm4
uniprot id: A0A3P8Y675
uniprot id: A0A3P8ZYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

8010:LOC105021649
gene id: 8010:LOC105021649
uniprot id: A0A3P9A6N6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:uba5
gene id: 8010:uba5
uniprot id: A0A3P8XIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

8010:ctsd
gene id: 8010:ctsd
uniprot id: A0A3P8YSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8010:tmtc2a
gene id: 8010:tmtc2a
uniprot id: A0A3P8ZB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8010:LOC105008246
gene id: 8010:LOC105008246
uniprot id: A0A3P8XRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:ube2ib
gene id: 8010:ube2ib
uniprot id: A0A6Q2X9V9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:fktn
gene id: 8010:fktn
uniprot id: A0A3P8YBR1
names: Similarity
messages: Belongs to the LicD transferase family.

8010:nedd9
gene id: 8010:nedd9
uniprot id: A0A3P8XPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8010:LOC105027599
gene id: 8010:LOC105027599
uniprot id: A0A3P8ZJV0
names: Similarity
messages: Belongs to the intermediate filament family.

8010:LOC105024826
gene id: 8010:LOC105024826
uniprot id: A0A3P8ZU12
names: Similarity
messages: Belongs to the SAPAP family.

8010:ctps1a
gene id: 8010:ctps1a
uniprot id: A0A3P8XZB4
uniprot id: A0A3P8Y101
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8010:LOC117592720
gene id: 8010:LOC117592720
uniprot id: A0A3P8ZAR4
names: Similarity
messages: Belongs to the serpin family.

8010:miox
gene id: 8010:miox
uniprot id: A0A3P9AK43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

8010:sufu
gene id: 8010:sufu
uniprot id: A0A3P9AIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

8010:sec11a
gene id: 8010:sec11a
uniprot id: C1BYD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105013010
gene id: 8010:LOC105013010
uniprot id: A0A3P8XMB9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8010:LOC105030991
gene id: 8010:LOC105030991
uniprot id: A0A3P8ZM42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:si:ch73-374l24.1
gene id: 8010:si:ch73-374l24.1
uniprot id: A0A3P8XLB3
uniprot id: A0A3P8ZJG2
uniprot id: A0A6Q2XDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

8010:scube2
gene id: 8010:scube2
uniprot id: A0A3P8XSI4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105009185
gene id: 8010:LOC105009185
uniprot id: A0A3P8Z4L3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Belongs to the TENT family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:glrx
gene id: 8010:glrx
uniprot id: A0A6Q2YZA6
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8010:vgll2a
gene id: 8010:vgll2a
uniprot id: A0A3P9AJ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8010:mlh1
gene id: 8010:mlh1
uniprot id: A0A3P8Y4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

8010:cd53
gene id: 8010:cd53
uniprot id: A0A3P8XFF6
uniprot id: C1BYG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:pou5f3
gene id: 8010:pou5f3
uniprot id: A0A3P8XWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:rdh5
gene id: 8010:rdh5
uniprot id: A0A3P8YTP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:acod1
gene id: 8010:acod1
uniprot id: A0A3P8ZXR1
names: Similarity
messages: Belongs to the PrpD family.

8010:LOC105014154
gene id: 8010:LOC105014154
uniprot id: C1BX21
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8010:dkc1
gene id: 8010:dkc1
uniprot id: A0A3P9A4I0
uniprot id: A0A6Q2XJ07
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8010:vac14
gene id: 8010:vac14
uniprot id: A0A3P9A2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

8010:LOC105015691
gene id: 8010:LOC105015691
uniprot id: A0A3P8ZM57
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:si:dkey-239i20.4
gene id: 8010:si:dkey-239i20.4
uniprot id: A0A3P8XSM6
uniprot id: A0A6Q2Z9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8010:bet1l
gene id: 8010:bet1l
uniprot id: A0A6Q2YPV8
names: Subcellular Location Annotation
messages: Membrane

8010:tns2a
gene id: 8010:tns2a
uniprot id: A0A3P8Y6R9
uniprot id: A0A3P8Y8B8
uniprot id: A0A6Q2WTR1
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8010:neu1
gene id: 8010:neu1
uniprot id: A0A3P8XQT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8010:acp7
gene id: 8010:acp7
uniprot id: A0A3P8ZKK9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

8010:trdmt1
gene id: 8010:trdmt1
uniprot id: A0A3P8ZDR9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

8010:nt5dc2
gene id: 8010:nt5dc2
uniprot id: A0A3P8XMA3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8010:LOC105020549
gene id: 8010:LOC105020549
uniprot id: A0A3P8XFU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

8010:LOC105029211
gene id: 8010:LOC105029211
uniprot id: A0A3P8YY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:tmem205
gene id: 8010:tmem205
uniprot id: A0A6Q2XPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8010:etv5a
gene id: 8010:etv5a
uniprot id: A0A3P8ZM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:LOC105011076
gene id: 8010:LOC105011076
uniprot id: A0A3P8XX08
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105022255
gene id: 8010:LOC105022255
uniprot id: A0A3P8XYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8010:LOC105021992
gene id: 8010:LOC105021992
uniprot id: A0A3P8Y781
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

8010:si:dkey-21c19.3
gene id: 8010:si:dkey-21c19.3
uniprot id: A0A3P8ZP75
names: Similarity
messages: Belongs to the peptidase C48 family.

8010:rab27a
gene id: 8010:rab27a
uniprot id: A0A3P8Y830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8010:prdm1a
gene id: 8010:prdm1a
uniprot id: A0A3P8ZVL7
uniprot id: A0A3P8ZW20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8010:atp6v1d
gene id: 8010:atp6v1d
uniprot id: C1BXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

8010:LOC105022187
gene id: 8010:LOC105022187
uniprot id: A0A3P9ALT0
names: Function
names: Similarity
messages: Belongs to the peptidase A1 family.
messages: Hydrolyzes a variety of proteins.

8010:gpr18
gene id: 8010:gpr18
uniprot id: A0A3P8YUC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

8010:nsdhl
gene id: 8010:nsdhl
uniprot id: A0A3P8XEU5
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8010:acap3a
gene id: 8010:acap3a
uniprot id: A0A3P8XKM0
uniprot id: A0A3P8ZI84
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8010:chrm5a
gene id: 8010:chrm5a
uniprot id: A0A3P8XIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8010:map6a
gene id: 8010:map6a
uniprot id: A0A3P8ZAE1
uniprot id: A0A3P9APE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8010:LOC105023108
gene id: 8010:LOC105023108
uniprot id: A0A3P8Y7D1
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8010:ccnd3
gene id: 8010:ccnd3
uniprot id: A0A3P8YBW7
names: Similarity
messages: Belongs to the cyclin family.

8010:LOC106024546
gene id: 8010:LOC106024546
uniprot id: A0A3P8ZP30
names: Similarity
messages: Belongs to the LSM12 family.

8010:sars1
gene id: 8010:sars1
uniprot id: A0A3P8ZZ72
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8010:hcrtr2
gene id: 8010:hcrtr2
uniprot id: A0A3P9AGI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:taf7
gene id: 8010:taf7
uniprot id: A0A3P8XD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

8010:LOC105022730
gene id: 8010:LOC105022730
uniprot id: A0A3P8YX70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105011043
gene id: 8010:LOC105011043
uniprot id: A0A3P8YMJ9
uniprot id: A0A3P8YMK3
uniprot id: A0A3P9A9S3
names: Similarity
messages: Belongs to the FAM168 family.

8010:pnx
gene id: 8010:pnx
uniprot id: A0A3P8XDV5
names: Subcellular Location Annotation
messages: Nucleus

8010:fzd5
gene id: 8010:fzd5
uniprot id: A0A3P8XI65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:wnt8b
gene id: 8010:wnt8b
uniprot id: A0A3P9APT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:LOC105024284
gene id: 8010:LOC105024284
uniprot id: A0A3P8YXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:zfp36l1a
gene id: 8010:zfp36l1a
uniprot id: A0A3P8Z2Y3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8010:LOC105019997
gene id: 8010:LOC105019997
uniprot id: A0A3P9ALB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105021270
gene id: 8010:LOC105021270
uniprot id: A0A3P8ZTX2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:kcnj11l
gene id: 8010:kcnj11l
uniprot id: A0A3P9APC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:nell2b
gene id: 8010:nell2b
uniprot id: A0A3P8Z036
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:mtch2
gene id: 8010:mtch2
uniprot id: C1BZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:uck1
gene id: 8010:uck1
uniprot id: A0A6Q2ZKM8
names: Similarity
messages: Belongs to the uridine kinase family.

8010:mmaa
gene id: 8010:mmaa
uniprot id: A0A3P8YCP0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

8010:si:ch73-195i19.3
gene id: 8010:si:ch73-195i19.3
uniprot id: A0A3P8XE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:irx5b
gene id: 8010:irx5b
uniprot id: A0A3P8YN76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8010:nfrkb
gene id: 8010:nfrkb
uniprot id: A0A3P8YTF0
names: Subcellular Location Annotation
messages: Nucleus

8010:dtnbp1a
gene id: 8010:dtnbp1a
uniprot id: A0A3P8XTP1
names: Similarity
messages: Belongs to the dysbindin family.

8010:tshz3a
gene id: 8010:tshz3a
uniprot id: A0A3P8YV81
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8010:prdm4
gene id: 8010:prdm4
uniprot id: A0A3P9A5L9
names: Subcellular Location Annotation
messages: Nucleus

8010:b4galt3
gene id: 8010:b4galt3
uniprot id: A0A3P8XZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8010:mrps31
gene id: 8010:mrps31
uniprot id: A0A3P8YFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

8010:dlgap1a
gene id: 8010:dlgap1a
uniprot id: A0A3P8Y8D2
names: Similarity
messages: Belongs to the SAPAP family.

8010:LOC105021842
gene id: 8010:LOC105021842
uniprot id: A0A3P8XWD3
uniprot id: A0A3P8XY46
uniprot id: A0A3P8XZB3
uniprot id: A0A3P8ZSQ0
uniprot id: A0A3P8ZU00
uniprot id: A0A6Q2Y791
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8010:LOC105014506
gene id: 8010:LOC105014506
uniprot id: A0A3P8ZBZ0
names: Similarity
messages: Belongs to the YOS1 family.

8010:stambpl1
gene id: 8010:stambpl1
uniprot id: A0A3P8ZG40
names: Similarity
messages: Belongs to the peptidase M67C family.

8010:rps8a
gene id: 8010:rps8a
uniprot id: C1BXM3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

8010:eif2d
gene id: 8010:eif2d
uniprot id: A0A3P8X7I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

8010:LOC105007477
gene id: 8010:LOC105007477
uniprot id: A0A3P8XUA1
names: Subcellular Location Annotation
messages: Membrane

8010:grnb
gene id: 8010:grnb
uniprot id: A0A3P8ZML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8010:LOC105019969
gene id: 8010:LOC105019969
uniprot id: A0A3P8YN14
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8010:unc5db
gene id: 8010:unc5db
uniprot id: A0A3P8XGF6
uniprot id: A0A3P8ZHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8010:LOC105014132
gene id: 8010:LOC105014132
uniprot id: A0A3P8ZC05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8010:trappc3
gene id: 8010:trappc3
uniprot id: C1BX92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

8010:c8g
gene id: 8010:c8g
uniprot id: A0A3P8Y597
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8010:scamp4
gene id: 8010:scamp4
uniprot id: A0A3P9A6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8010:atg9a
gene id: 8010:atg9a
uniprot id: A0A6Q2XIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

8010:LOC105017087
gene id: 8010:LOC105017087
uniprot id: A0A3P8Z400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:srsf5a
gene id: 8010:srsf5a
uniprot id: A0A3P9AHA3
names: Similarity
messages: Belongs to the splicing factor SR family.

8010:epha8
gene id: 8010:epha8
uniprot id: A0A3P8Y9F9
uniprot id: A0A6Q2WZZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:thumpd2
gene id: 8010:thumpd2
uniprot id: A0A3P8XCL3
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8010:LOC105020584
gene id: 8010:LOC105020584
uniprot id: A0A6Q2Y6J0
names: Similarity
messages: Belongs to the cornifelin family.

8010:rpl36
gene id: 8010:rpl36
uniprot id: C1BXB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

8010:emc9
gene id: 8010:emc9
uniprot id: A0A3P8YH29
uniprot id: A0A3P8YH30
uniprot id: C1BYS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC8/EMC9 family.
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:spry1
gene id: 8010:spry1
uniprot id: A0A3P8Z3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

8010:mgmt
gene id: 8010:mgmt
uniprot id: A0A3P8ZM90
names: Similarity
messages: Belongs to the MGMT family.

8010:LOC105024544
gene id: 8010:LOC105024544
uniprot id: A0A3P8Y0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:dtd2
gene id: 8010:dtd2
uniprot id: A0A6Q2WXK1
names: Similarity
messages: Belongs to the DTD family.

8010:ace2
gene id: 8010:ace2
uniprot id: A0A3P8ZXN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

8010:ccser1
gene id: 8010:ccser1
uniprot id: A0A3P8YRY6
names: Similarity
messages: Belongs to the CCSER family.

8010:zgc:92275
gene id: 8010:zgc:92275
uniprot id: A0A3P8YKB6
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

8010:LOC105019642
gene id: 8010:LOC105019642
uniprot id: A0A3P8ZNQ6
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

8010:cab39l1
gene id: 8010:cab39l1
uniprot id: A0A3P8XWQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8010:cluap1
gene id: 8010:cluap1
uniprot id: A0A3P8XWU5
uniprot id: A0A3P8XWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

8010:mpp3a
gene id: 8010:mpp3a
uniprot id: A0A3P8YHS8
uniprot id: A0A3P8YJ86
uniprot id: A0A3P8YJW2
names: Similarity
messages: Belongs to the MAGUK family.

8010:stmn4
gene id: 8010:stmn4
uniprot id: A0A3P8XYI0
names: Similarity
messages: Belongs to the stathmin family.

8010:entpd3
gene id: 8010:entpd3
uniprot id: A0A3P8XPB2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8010:mtif2
gene id: 8010:mtif2
uniprot id: A0A3P8XCG9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

8010:LOC109614542
gene id: 8010:LOC109614542
uniprot id: A0A3P8ZJ82
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8010:ppargc1a
gene id: 8010:ppargc1a
uniprot id: A0A3P8YN62
names: Subcellular Location Annotation
messages: PML body

8010:LOC105006430
gene id: 8010:LOC105006430
uniprot id: A0A3P9ABU3
names: Subcellular Location Annotation
messages: Membrane

8010:shrprbck1r
gene id: 8010:shrprbck1r
uniprot id: A0A3P8YHX0
names: Similarity
messages: Belongs to the RBR family.

8010:becn1
gene id: 8010:becn1
uniprot id: A0A3P8XNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

8010:tmem200ca
gene id: 8010:tmem200ca
uniprot id: A0A3P8YUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8010:zgc:171579
gene id: 8010:zgc:171579
uniprot id: A0A3P9A0L7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:thrsp
gene id: 8010:thrsp
uniprot id: A0A3P8Z7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8010:tnfaip3
gene id: 8010:tnfaip3
uniprot id: A0A6Q2XAK8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:mrpl11
gene id: 8010:mrpl11
uniprot id: A0A3P8ZD98
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8010:rgn
gene id: 8010:rgn
uniprot id: C1BWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

8010:dipk2b
gene id: 8010:dipk2b
uniprot id: A0A3P9ACJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

8010:LOC105008087
gene id: 8010:LOC105008087
uniprot id: A0A3P8ZPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:cavin4b
gene id: 8010:cavin4b
uniprot id: A0A3P9AAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8010:slc66a3
gene id: 8010:slc66a3
uniprot id: C1BXJ8
names: Subcellular Location Annotation
messages: Membrane

8010:dipk1aa
gene id: 8010:dipk1aa
uniprot id: A0A3P9AE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8010:mrpl34
gene id: 8010:mrpl34
uniprot id: A0A6Q2XG46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

8010:tacr3a
gene id: 8010:tacr3a
uniprot id: A0A3P8ZH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:cxcr3.2
gene id: 8010:cxcr3.2
uniprot id: A0A6Q2XXN8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:slc16a5b
gene id: 8010:slc16a5b
uniprot id: A0A3P8Y7C9
names: Subcellular Location Annotation
messages: Membrane

8010:kcns3b
gene id: 8010:kcns3b
uniprot id: A0A3P8YDH5
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105026335
gene id: 8010:LOC105026335
uniprot id: A0A3P8YAB7
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8010:serpinh1b
gene id: 8010:serpinh1b
uniprot id: A0A3P8YJP9
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8010:dmap1
gene id: 8010:dmap1
uniprot id: A0A3P9A4H5
names: Subcellular Location Annotation
messages: Nucleus

8010:nsa2
gene id: 8010:nsa2
uniprot id: C1BWQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

8010:mcoln1a
gene id: 8010:mcoln1a
uniprot id: A0A3P9A1J1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8010:rp2
gene id: 8010:rp2
uniprot id: A0A3P8YK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

8010:LOC109615628
gene id: 8010:LOC109615628
uniprot id: A0A3P8XXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:rragcb
gene id: 8010:rragcb
uniprot id: A0A3P8ZP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8010:LOC105014463
gene id: 8010:LOC105014463
uniprot id: A0A3P8XDJ4
uniprot id: A0A3P8XDJ9
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8010:LOC105006877
gene id: 8010:LOC105006877
uniprot id: A0A3P8XXY3
names: Subcellular Location Annotation
messages: Membrane

8010:si:dkey-33m11.6
gene id: 8010:si:dkey-33m11.6
uniprot id: A0A6Q2X3A2
names: Similarity
messages: Belongs to the CAMK2N family.

8010:slc6a8
gene id: 8010:slc6a8
uniprot id: A0A3P8ZUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:os9
gene id: 8010:os9
uniprot id: A0A3P9A5I2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

8010:slc6a18
gene id: 8010:slc6a18
uniprot id: A0A3P8YIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:gba3
gene id: 8010:gba3
uniprot id: A0A3P9A8N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8010:nptx2a
gene id: 8010:nptx2a
uniprot id: A0A3P8XN36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105018894
gene id: 8010:LOC105018894
uniprot id: A0A6Q2ZGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8010:cass4
gene id: 8010:cass4
uniprot id: A0A3P9A2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8010:tyw3
gene id: 8010:tyw3
uniprot id: A0A3P8Z5W2
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

8010:poglut2
gene id: 8010:poglut2
uniprot id: A0A3P9A478
uniprot id: A0A6Q2ZEW5
names: Similarity
messages: Belongs to the KDELC family.

8010:si:dkey-119f1.1
gene id: 8010:si:dkey-119f1.1
uniprot id: A0A3P9ACJ9
names: Subcellular Location Annotation
messages: Chromosome

8010:fitm2
gene id: 8010:fitm2
uniprot id: A0A3P8XM40
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105029259
gene id: 8010:LOC105029259
uniprot id: A0A3P8Y8A5
names: Subcellular Location Annotation
messages: Membrane

8010:chs1
gene id: 8010:chs1
uniprot id: A0A3P9AEH6
names: Subcellular Location Annotation
messages: Membrane

8010:si:dkey-79d12.5
gene id: 8010:si:dkey-79d12.5
uniprot id: A0A3P9AIX3
names: Similarity
messages: Belongs to the BTG family.

8010:nog3
gene id: 8010:nog3
uniprot id: A0A3P8Z557
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8010:LOC105024665
gene id: 8010:LOC105024665
uniprot id: A0A3P8ZJY5
uniprot id: A0A6Q2WV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8010:dse
gene id: 8010:dse
uniprot id: A0A3P8YNQ8
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

8010:LOC105016647
gene id: 8010:LOC105016647
uniprot id: A0A3P9AAD5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8010:impact
gene id: 8010:impact
uniprot id: C1BWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

8010:ggt5a
gene id: 8010:ggt5a
uniprot id: A0A3P8Z5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8010:tbc1d24
gene id: 8010:tbc1d24
uniprot id: A0A3P8XU67
names: Subcellular Location Annotation
messages: Membrane

8010:ing2
gene id: 8010:ing2
uniprot id: A0A3P8ZTT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8010:ephx5
gene id: 8010:ephx5
uniprot id: A0A3P8Y765
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8010:si:dkey-246i14.3
gene id: 8010:si:dkey-246i14.3
uniprot id: A0A3P8Y458
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:ccr9b
gene id: 8010:ccr9b
uniprot id: A0A3P8XLM7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:sdhc
gene id: 8010:sdhc
uniprot id: A0A3P8Y5J7
uniprot id: C1BZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

8010:ssbp1
gene id: 8010:ssbp1
uniprot id: C1BX09
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8010:mcm7
gene id: 8010:mcm7
uniprot id: A0A3P8ZAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

8010:LOC105009037
gene id: 8010:LOC105009037
uniprot id: A0A3P8XYC0
names: Subunit
messages: Monomer.

8010:gdpd5b
gene id: 8010:gdpd5b
uniprot id: A0A3P9A778
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:slc26a10
gene id: 8010:slc26a10
uniprot id: A0A3P8XV61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:zgc:85932
gene id: 8010:zgc:85932
uniprot id: A0A3P8YN75
names: Similarity
messages: Belongs to the peptidase C2 family.

8010:cd99l2
gene id: 8010:cd99l2
uniprot id: A0A3P8Y0Y4
uniprot id: A0A3P8Y3R0
names: Similarity
messages: Belongs to the CD99 family.

8010:LOC105022375
gene id: 8010:LOC105022375
uniprot id: A0A3P8Z190
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:tnfrsf21
gene id: 8010:tnfrsf21
uniprot id: A0A3P8XE76
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105017052
gene id: 8010:LOC105017052
uniprot id: A0A3P8Z8L5
uniprot id: A0A3P9ANP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8010:soat2
gene id: 8010:soat2
uniprot id: A0A3P8Y1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:fshr
gene id: 8010:fshr
uniprot id: A0A3P8XE74
uniprot id: A0A6Q2YKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

8010:plxnd1
gene id: 8010:plxnd1
uniprot id: A0A3P8Z6E8
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ppil4
gene id: 8010:ppil4
uniprot id: A0A3P8YS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:fat1a
gene id: 8010:fat1a
uniprot id: A0A3P9AI22
uniprot id: A0A3P9AIA6
uniprot id: A0A3P9AIB5
uniprot id: A0A3P9AIE2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:spon1b
gene id: 8010:spon1b
uniprot id: A0A3P8YJK8
names: Subcellular Location Annotation
messages: extracellular matrix

8010:spdl1
gene id: 8010:spdl1
uniprot id: A0A3P9A317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

8010:hps5
gene id: 8010:hps5
uniprot id: A0A3P9AM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

8010:LOC105005823
gene id: 8010:LOC105005823
uniprot id: A0A3P8ZFK3
uniprot id: A0A6Q2XPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8010:agrn
gene id: 8010:agrn
uniprot id: A0A3P8XFY6
uniprot id: A0A3P8XJL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:slc16a6b
gene id: 8010:slc16a6b
uniprot id: A0A6Q2YVT1
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105014502
gene id: 8010:LOC105014502
uniprot id: A0A3P8X816
uniprot id: A0A3P8XAF4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:LOC105027615
gene id: 8010:LOC105027615
uniprot id: A0A3P8ZMI0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

8010:cd9b
gene id: 8010:cd9b
uniprot id: A0A3P8Y050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8010:bdnf
gene id: 8010:bdnf
uniprot id: A0A3P8XZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

8010:LOC105017040
gene id: 8010:LOC105017040
uniprot id: A0A3P8YG94
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8010:haus8
gene id: 8010:haus8
uniprot id: A0A3P8YQ34
names: Similarity
messages: Belongs to the QWRF family.

8010:LOC105014093
gene id: 8010:LOC105014093
uniprot id: A0A3P8XB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8010:LOC105017911
gene id: 8010:LOC105017911
uniprot id: A0A3P8YUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

8010:LOC105020000
gene id: 8010:LOC105020000
uniprot id: A0A3P8Z4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8010:cnpy2
gene id: 8010:cnpy2
uniprot id: C1BWT2
names: Similarity
messages: Belongs to the canopy family.

8010:LOC105016726
gene id: 8010:LOC105016726
uniprot id: A0A3P8YAA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:pkn1a
gene id: 8010:pkn1a
uniprot id: A0A3P8Y4Z2
uniprot id: A0A3P8ZW07
uniprot id: A0A3P8ZXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8010:sart1
gene id: 8010:sart1
uniprot id: A0A3P8YIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

8010:nxf1
gene id: 8010:nxf1
uniprot id: A0A3P9A5W2
uniprot id: A0A6Q2YXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

8010:LOC105015658
gene id: 8010:LOC105015658
uniprot id: A0A3P8XH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8010:LOC105031654
gene id: 8010:LOC105031654
uniprot id: A0A6Q2YSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:dspa
gene id: 8010:dspa
uniprot id: A0A3P9ADK6
names: Subcellular Location Annotation
messages: cytoskeleton

8010:LOC105006728
gene id: 8010:LOC105006728
uniprot id: A0A3P8Y310
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105011049
gene id: 8010:LOC105011049
uniprot id: A0A3P9ABI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

8010:asip2b
gene id: 8010:asip2b
uniprot id: A0A3P9ANI0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105022482
gene id: 8010:LOC105022482
uniprot id: A0A3P9AI34
uniprot id: A0A6Q2XRP4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8010:LOC105021252
gene id: 8010:LOC105021252
uniprot id: A0A6Q2WWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8010:rcan2
gene id: 8010:rcan2
uniprot id: A0A3P8XH57
uniprot id: A0A3P8ZGF0
names: Similarity
messages: Belongs to the RCAN family.

8010:abcc6a
gene id: 8010:abcc6a
uniprot id: A0A3P8XCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8010:zgc:163121
gene id: 8010:zgc:163121
uniprot id: A0A3P8Y9T2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8010:LOC105023822
gene id: 8010:LOC105023822
uniprot id: A0A3P8YNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:lrp12
gene id: 8010:lrp12
uniprot id: A0A6Q2XDE2
uniprot id: A0A6Q2YJH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:mmp16b
gene id: 8010:mmp16b
uniprot id: A0A3P9AP34
uniprot id: A0A3P9APW8
uniprot id: A0A6Q2YMF9
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:pigw
gene id: 8010:pigw
uniprot id: A0A3P9AE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

8010:LOC105030300
gene id: 8010:LOC105030300
uniprot id: A0A3P8YI85
uniprot id: A0A3P9A7L0
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8010:nupr1b
gene id: 8010:nupr1b
uniprot id: C1BWA2
names: Similarity
messages: Belongs to the NUPR family.

8010:apoda.2
gene id: 8010:apoda.2
uniprot id: A0A6Q2ZKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8010:spp2
gene id: 8010:spp2
uniprot id: C1BYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

8010:tctex1d1
gene id: 8010:tctex1d1
uniprot id: A0A6Q2XRW3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8010:nog1
gene id: 8010:nog1
uniprot id: A0A3P9AAH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8010:itga11b
gene id: 8010:itga11b
uniprot id: A0A3P8ZE86
uniprot id: A0A3P8ZEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:LOC105021824
gene id: 8010:LOC105021824
uniprot id: A0A3P8XTJ7
uniprot id: A0A3P8XVN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

8010:lrrc42
gene id: 8010:lrrc42
uniprot id: A0A3P9A4A2
names: Similarity
messages: Belongs to the LRRC42 family.

8010:LOC105029222
gene id: 8010:LOC105029222
uniprot id: A0A6Q2YAX4
names: Similarity
messages: Belongs to the BZW family.

8010:jpt1
gene id: 8010:jpt1
uniprot id: A0A3P8XTJ0
uniprot id: A0A3P8XUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8010:calhm6
gene id: 8010:calhm6
uniprot id: A0A3P8Z2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8010:LOC105005986
gene id: 8010:LOC105005986
uniprot id: A0A3P8YT55
uniprot id: A0A3P9AE37
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

8010:xkr5b
gene id: 8010:xkr5b
uniprot id: A0A3P8YRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:fahd2a
gene id: 8010:fahd2a
uniprot id: A0A3P8XV60
names: Similarity
messages: Belongs to the FAH family.

8010:naa30
gene id: 8010:naa30
uniprot id: A0A3P8ZYC7
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

8010:cpne7
gene id: 8010:cpne7
uniprot id: A0A3P8YEU0
uniprot id: A0A6Q2XUZ4
names: Similarity
messages: Belongs to the copine family.

8010:pomgnt2
gene id: 8010:pomgnt2
uniprot id: A0A3P8ZMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105012566
gene id: 8010:LOC105012566
uniprot id: A0A3P8ZQI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

8010:stxbp2
gene id: 8010:stxbp2
uniprot id: A0A3P8ZYT6
uniprot id: A0A6Q2Z9K5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8010:cep20
gene id: 8010:cep20
uniprot id: C1BX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8010:mgat2
gene id: 8010:mgat2
uniprot id: A0A3P8ZXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

8010:napgb
gene id: 8010:napgb
uniprot id: A0A3P8XSH7
names: Similarity
messages: Belongs to the SNAP family.

8010:LOC105012866
gene id: 8010:LOC105012866
uniprot id: A0A3P8YFM6
uniprot id: A0A3P9A4X5
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:bola1
gene id: 8010:bola1
uniprot id: A0A3P8ZYQ2
names: Similarity
messages: Belongs to the BolA/IbaG family.

8010:zdhhc8b
gene id: 8010:zdhhc8b
uniprot id: A0A3P8XQZ7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:cope
gene id: 8010:cope
uniprot id: C1BZK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8010:ognb
gene id: 8010:ognb
uniprot id: A0A3P8X9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

8010:apoa1b
gene id: 8010:apoa1b
uniprot id: A0A6Q2WW35
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8010:cplx2
gene id: 8010:cplx2
uniprot id: A0A3P9AJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8010:yaf2
gene id: 8010:yaf2
uniprot id: A0A6Q2YVX7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105024728
gene id: 8010:LOC105024728
uniprot id: A0A3P8ZI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8010:svopa
gene id: 8010:svopa
uniprot id: A0A3P8Y7M0
uniprot id: A0A6Q2YRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8010:LOC105020620
gene id: 8010:LOC105020620
uniprot id: A0A3P8YMB1
uniprot id: A0A3P8YPF6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

8010:atp1a2a
gene id: 8010:atp1a2a
uniprot id: A0A3P8Y5G6
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.

8010:ccdc93
gene id: 8010:ccdc93
uniprot id: A0A3P8ZMC0
uniprot id: A0A3P8ZMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

8010:grin1a
gene id: 8010:grin1a
uniprot id: A0A3P8YJJ2
uniprot id: A0A3P8YJK4
uniprot id: A0A3P8YLQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:LOC105010775
gene id: 8010:LOC105010775
uniprot id: A0A3P8ZB20
uniprot id: A0A6Q2WYP3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8010:kremen1
gene id: 8010:kremen1
uniprot id: A0A3P8XHH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105031062
gene id: 8010:LOC105031062
uniprot id: A0A3P8XWS6
uniprot id: A0A3P8ZR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:chrm4a
gene id: 8010:chrm4a
uniprot id: A0A6Q2YXT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8010:LOC105013282
gene id: 8010:LOC105013282
uniprot id: C1BY40
names: Similarity
messages: Belongs to the NDK family.

8010:ntn5
gene id: 8010:ntn5
uniprot id: A0A3P8YTH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cntnap3
gene id: 8010:cntnap3
uniprot id: A0A3P8XFL7
uniprot id: A0A3P8XFT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:si:ch211-126j24.1
gene id: 8010:si:ch211-126j24.1
uniprot id: A0A3P8YK03
uniprot id: A0A3P9A8U5
names: Similarity
messages: Belongs to the PACS family.

8010:mtnr1aa
gene id: 8010:mtnr1aa
uniprot id: A0A3P9AHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8010:tm4sf4
gene id: 8010:tm4sf4
uniprot id: A0A3P8Y2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8010:foxo4
gene id: 8010:foxo4
uniprot id: A0A3P8X997
names: Subcellular Location Annotation
messages: Nucleus

8010:nol10
gene id: 8010:nol10
uniprot id: A0A3P8YDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

8010:tead3b
gene id: 8010:tead3b
uniprot id: A0A3P8Z1K4
uniprot id: A0A3P8Z1M4
uniprot id: A0A3P8Z2D5
uniprot id: A0A3P8Z371
uniprot id: A0A3P9AJS7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

8010:nfu1
gene id: 8010:nfu1
uniprot id: C1BZM3
names: Similarity
messages: Belongs to the NifU family.

8010:LOC105027514
gene id: 8010:LOC105027514
uniprot id: A0A3P8ZJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:ncstn
gene id: 8010:ncstn
uniprot id: A0A3P8XCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

8010:dad1
gene id: 8010:dad1
uniprot id: C1BZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8010:acat2
gene id: 8010:acat2
uniprot id: A0A3P8YNE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8010:LOC105024967
gene id: 8010:LOC105024967
uniprot id: A0A3P8YRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:mterf4
gene id: 8010:mterf4
uniprot id: A0A3P8Y2H7
names: Similarity
messages: Belongs to the mTERF family.

8010:LOC105009870
gene id: 8010:LOC105009870
uniprot id: A0A3P8ZZP0
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:slc17a5
gene id: 8010:slc17a5
uniprot id: A0A3P8Y7E8
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105025978
gene id: 8010:LOC105025978
uniprot id: C1BYX3
names: Subcellular Location Annotation
messages: Membrane

8010:ankha
gene id: 8010:ankha
uniprot id: A0A3P8ZNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8010:lbr
gene id: 8010:lbr
uniprot id: A0A3P8ZFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

8010:LOC105025829
gene id: 8010:LOC105025829
uniprot id: A0A3P9A6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8010:aspn
gene id: 8010:aspn
uniprot id: A0A3P8YFG2
uniprot id: A0A3P8YGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

8010:atp5mf
gene id: 8010:atp5mf
uniprot id: A0A3P8ZXR0
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

8010:crhbp
gene id: 8010:crhbp
uniprot id: A0A3P8ZNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8010:ripk3
gene id: 8010:ripk3
uniprot id: A0A3P8XYF2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105013628
gene id: 8010:LOC105013628
uniprot id: A0A3P8XPX9
uniprot id: A0A6Q2Y4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:efna5b
gene id: 8010:efna5b
uniprot id: A0A6Q2ZEC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:scdb
gene id: 8010:scdb
uniprot id: A0A3P8ZAH5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8010:esrp1
gene id: 8010:esrp1
uniprot id: A0A3P8XYM5
uniprot id: A0A3P8ZTP2
names: Subcellular Location Annotation
messages: Nucleus

8010:slc35a4
gene id: 8010:slc35a4
uniprot id: A0A3P8YJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8010:mknk2b
gene id: 8010:mknk2b
uniprot id: A0A3P8YBW1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:zgc:162200
gene id: 8010:zgc:162200
uniprot id: A0A3P8Z0S0
names: Similarity
messages: Belongs to the BicD family.

8010:LOC105010090
gene id: 8010:LOC105010090
uniprot id: A0A3P8ZG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Membrane

8010:eif4g2b
gene id: 8010:eif4g2b
uniprot id: A0A3P8ZY72
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8010:b3gnt2a
gene id: 8010:b3gnt2a
uniprot id: A0A3P8Y6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:il4i1
gene id: 8010:il4i1
uniprot id: A0A3P8Z773
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8010:rxfp2a
gene id: 8010:rxfp2a
uniprot id: A0A3P8ZP82
uniprot id: A0A3P8ZPB0
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:ap2m1b
gene id: 8010:ap2m1b
uniprot id: A0A3P8XL94
uniprot id: A0A3P8XLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules.
messages: coated pit

8010:parp12a
gene id: 8010:parp12a
uniprot id: A0A3P8YUC5
names: Similarity
messages: Belongs to the ARTD/PARP family.

8010:LOC105029074
gene id: 8010:LOC105029074
uniprot id: A0A3P8YHR2
uniprot id: A0A3P9A5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

8010:LOC105008971
gene id: 8010:LOC105008971
uniprot id: A0A3P9AQD6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:st8sia4
gene id: 8010:st8sia4
uniprot id: A0A3P8YP86
uniprot id: A0A6Q2Y239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:LOC105026877
gene id: 8010:LOC105026877
uniprot id: A0A3P9AEN1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:fam122b
gene id: 8010:fam122b
uniprot id: A0A3P8Y041
names: Similarity
messages: Belongs to the FAM122 family.

8010:ttyh3a
gene id: 8010:ttyh3a
uniprot id: A0A3P8YWT4
uniprot id: A0A3P8YWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8010:zgc:158260
gene id: 8010:zgc:158260
uniprot id: A0A3P8YE54
names: Similarity
messages: Belongs to the FAM47 family.

8010:prkx
gene id: 8010:prkx
uniprot id: A0A3P8YM48
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:atp5pd
gene id: 8010:atp5pd
uniprot id: C1BZH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8010:barhl2
gene id: 8010:barhl2
uniprot id: A0A3P8XDY6
names: Subcellular Location Annotation
messages: Nucleus

8010:npepps
gene id: 8010:npepps
uniprot id: A0A3P8XYG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8010:nudt21
gene id: 8010:nudt21
uniprot id: A0A3P8YKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

8010:si:ch211-13f8.2
gene id: 8010:si:ch211-13f8.2
uniprot id: A0A3P8Z7E4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8010:pparda
gene id: 8010:pparda
uniprot id: A0A3P8ZNG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:slc25a35
gene id: 8010:slc25a35
uniprot id: A0A3P8XIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:hsp90b1
gene id: 8010:hsp90b1
uniprot id: A0A3P8ZIZ8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8010:mrpl35
gene id: 8010:mrpl35
uniprot id: C1BYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

8010:plac8l1
gene id: 8010:plac8l1
uniprot id: A0A3P8Z873
names: Similarity
messages: Belongs to the cornifelin family.

8010:manba
gene id: 8010:manba
uniprot id: A0A3P8Z8A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Lysosome

8010:ccnd2a
gene id: 8010:ccnd2a
uniprot id: C1BZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

8010:srp14
gene id: 8010:srp14
uniprot id: A0A3P8XEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

8010:ttyh1
gene id: 8010:ttyh1
uniprot id: A0A3P8YGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8010:LOC105026318
gene id: 8010:LOC105026318
uniprot id: A0A3P8YE37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105014792
gene id: 8010:LOC105014792
uniprot id: A0A3P8X991
names: Similarity
messages: Belongs to the BCL7 family.

8010:ints11
gene id: 8010:ints11
uniprot id: A0A3P8ZHS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

8010:dedd1
gene id: 8010:dedd1
uniprot id: A0A3P9AB65
uniprot id: A0A3P9ACI6
names: Subcellular Location Annotation
messages: nucleolus

8010:pou6f2
gene id: 8010:pou6f2
uniprot id: A0A3P8XSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:LOC105018994
gene id: 8010:LOC105018994
uniprot id: A0A3P8YD68
uniprot id: A0A3P8YDC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cdkl1
gene id: 8010:cdkl1
uniprot id: A0A3P8YXR4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:sema6e
gene id: 8010:sema6e
uniprot id: A0A3P8Y2Q7
uniprot id: A0A3P8ZWI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:eno2
gene id: 8010:eno2
uniprot id: A0A3P8Z1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8010:ddx18
gene id: 8010:ddx18
uniprot id: A0A3P8XTY9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

8010:ndnfl
gene id: 8010:ndnfl
uniprot id: A0A3P8XMJ4
names: Subcellular Location Annotation
messages: Secreted

8010:LOC105007623
gene id: 8010:LOC105007623
uniprot id: A0A3P8X9G6
names: Subcellular Location Annotation
messages: Nucleus

8010:jph1b
gene id: 8010:jph1b
uniprot id: A0A3P9A348
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8010:slc25a19
gene id: 8010:slc25a19
uniprot id: A0A3P8ZNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:arxa
gene id: 8010:arxa
uniprot id: A0A3P8ZRQ7
names: Subcellular Location Annotation
messages: Nucleus

8010:tmem38a
gene id: 8010:tmem38a
uniprot id: A0A3P8ZZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8010:tbx21
gene id: 8010:tbx21
uniprot id: A0A3P8XWC2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:cpne5b
gene id: 8010:cpne5b
uniprot id: A0A3P8YV13
uniprot id: A0A3P8YW60
names: Similarity
messages: Belongs to the copine family.

8010:kat6a
gene id: 8010:kat6a
uniprot id: A0A3P8ZL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8010:LOC105031168
gene id: 8010:LOC105031168
uniprot id: A0A3P8Y3I5
uniprot id: A0A3P8ZW75
names: Subcellular Location Annotation
messages: Membrane

8010:mrpl40
gene id: 8010:mrpl40
uniprot id: C1BWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

8010:LOC105030438
gene id: 8010:LOC105030438
uniprot id: A0A3P8YSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8010:slc23a2
gene id: 8010:slc23a2
uniprot id: A0A3P8ZRY3
uniprot id: A0A3P8ZSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8010:scarb2c
gene id: 8010:scarb2c
uniprot id: A0A3P8X7B6
uniprot id: A0A3P8X9E6
names: Similarity
messages: Belongs to the CD36 family.

8010:hpdb
gene id: 8010:hpdb
uniprot id: A0A3P8Z6J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8010:soat1
gene id: 8010:soat1
uniprot id: A0A3P8ZQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:brinp2
gene id: 8010:brinp2
uniprot id: A0A3P8Y3F1
uniprot id: A0A3P8ZUX5
names: Similarity
messages: Belongs to the BRINP family.

8010:irak1bp1
gene id: 8010:irak1bp1
uniprot id: A0A3P8XRE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8010:tmem120a
gene id: 8010:tmem120a
uniprot id: A0A3P8YBY7
uniprot id: A0A6Q2ZNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8010:LOC105020254
gene id: 8010:LOC105020254
uniprot id: A0A3P8ZRB7
uniprot id: A0A6Q2YWS8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8010:LOC105023242
gene id: 8010:LOC105023242
uniprot id: A0A3P9A041
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:duox2
gene id: 8010:duox2
uniprot id: A0A3P8XJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

8010:fam131ba
gene id: 8010:fam131ba
uniprot id: A0A3P9AJ00
uniprot id: A0A3P9AJ09
uniprot id: A0A3P9AK29
names: Similarity
messages: Belongs to the FAM131 family.

8010:kif4
gene id: 8010:kif4
uniprot id: A0A3P8YEG2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:fam168b
gene id: 8010:fam168b
uniprot id: A0A3P8XAP3
names: Similarity
messages: Belongs to the FAM168 family.

8010:ssbp3b
gene id: 8010:ssbp3b
uniprot id: A0A3P8YG93
uniprot id: A0A3P9A5M0
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105025735
gene id: 8010:LOC105025735
uniprot id: A0A3P9AE73
names: Similarity
messages: Belongs to the SNAP family.

8010:derl2
gene id: 8010:derl2
uniprot id: C1BYR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105025742
gene id: 8010:LOC105025742
uniprot id: A0A3P9A787
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:foxi2
gene id: 8010:foxi2
uniprot id: A0A6Q2YJ79
names: Subcellular Location Annotation
messages: Nucleus

8010:rab18a
gene id: 8010:rab18a
uniprot id: A0A3P8XCX3
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8010:mid1ip1a
gene id: 8010:mid1ip1a
uniprot id: A0A3P8YUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8010:clic4
gene id: 8010:clic4
uniprot id: A0A3P8XG03
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8010:dazl
gene id: 8010:dazl
uniprot id: A0A3P8ZLF6
uniprot id: A0A6Q2YN62
names: Subcellular Location Annotation
messages: Cytoplasm

8010:mrpl22
gene id: 8010:mrpl22
uniprot id: A0A3P8Y193
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8010:LOC105012885
gene id: 8010:LOC105012885
uniprot id: C1BX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:amdhd2
gene id: 8010:amdhd2
uniprot id: A0A3P8XWC8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

8010:samd4a
gene id: 8010:samd4a
uniprot id: A0A3P8YGU9
uniprot id: A0A3P8YH06
uniprot id: A0A3P9A6S7
uniprot id: A0A6Q2YBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8010:zmp:0000001236
gene id: 8010:zmp:0000001236
uniprot id: A0A3P8Z813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8010:LOC105030743
gene id: 8010:LOC105030743
uniprot id: A0A3P8Y8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

8010:kif16ba
gene id: 8010:kif16ba
uniprot id: A0A3P8Y3A8
uniprot id: A0A3P8Y630
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:ap1m3
gene id: 8010:ap1m3
uniprot id: A0A3P8Z2S4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

8010:mrpl51
gene id: 8010:mrpl51
uniprot id: C1BYQ8
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

8010:LOC105023749
gene id: 8010:LOC105023749
uniprot id: A0A3P8Z4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8010:pycr1b
gene id: 8010:pycr1b
uniprot id: A0A3P9ACI0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8010:b3gnt7
gene id: 8010:b3gnt7
uniprot id: A0A3P8XP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105009699
gene id: 8010:LOC105009699
uniprot id: A0A3P8ZIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8010:fam167b
gene id: 8010:fam167b
uniprot id: A0A3P8ZEI6
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8010:slc35e4
gene id: 8010:slc35e4
uniprot id: A0A3P9AFS2
names: Subcellular Location Annotation
messages: Membrane

8010:ago2
gene id: 8010:ago2
uniprot id: A0A3P9AER1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

8010:ppl
gene id: 8010:ppl
uniprot id: A0A3P8ZWK8
names: Subcellular Location Annotation
messages: cytoskeleton

8010:psph
gene id: 8010:psph
uniprot id: A0A3P8ZPV8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

8010:rassf1
gene id: 8010:rassf1
uniprot id: A0A3P8XWW6
names: Subcellular Location Annotation
messages: cytoskeleton

8010:adcyap1b
gene id: 8010:adcyap1b
uniprot id: A0A3P8Y2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8010:snapin
gene id: 8010:snapin
uniprot id: A0A6Q2XRB4
names: Similarity
messages: Belongs to the SNAPIN family.

8010:msx1a
gene id: 8010:msx1a
uniprot id: A0A3P8ZW03
names: Subcellular Location Annotation
messages: Nucleus

8010:gga3b
gene id: 8010:gga3b
uniprot id: A0A3P8XQP1
uniprot id: A0A3P8XR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8010:fh
gene id: 8010:fh
uniprot id: A0A3P9A9Q1
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

8010:immt
gene id: 8010:immt
uniprot id: A0A3P8Y6W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8010:tnfrsfa
gene id: 8010:tnfrsfa
uniprot id: A0A3P8ZQZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:bcl2l1
gene id: 8010:bcl2l1
uniprot id: A0A3P8XYL5
names: Similarity
messages: Belongs to the Bcl-2 family.

8010:usp10
gene id: 8010:usp10
uniprot id: A0A3P9A241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

8010:cx47.1
gene id: 8010:cx47.1
uniprot id: A0A3P8Z4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:ppib
gene id: 8010:ppib
uniprot id: C1BY15
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:zfp36l2
gene id: 8010:zfp36l2
uniprot id: A0A3P9A5Z4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8010:tmem30c
gene id: 8010:tmem30c
uniprot id: A0A3P9AFC1
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8010:slc25a21
gene id: 8010:slc25a21
uniprot id: A0A3P8Z2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:elp6
gene id: 8010:elp6
uniprot id: A0A3P8Y0D7
names: Similarity
messages: Belongs to the ELP6 family.

8010:LOC105020085
gene id: 8010:LOC105020085
uniprot id: A0A3P8X9Z2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8010:fgf21
gene id: 8010:fgf21
uniprot id: A0A3P8ZNP8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:LOC105014950
gene id: 8010:LOC105014950
uniprot id: A0A3P8XMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:LOC109614640
gene id: 8010:LOC109614640
uniprot id: A0A3P8YV76
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8010:LOC105010803
gene id: 8010:LOC105010803
uniprot id: A0A3P8XUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:acap3b
gene id: 8010:acap3b
uniprot id: A0A3P8YHV7
uniprot id: A0A3P9A621
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8010:slc4a4b
gene id: 8010:slc4a4b
uniprot id: A0A3P8X9A2
uniprot id: A0A3P8X9E3
uniprot id: A0A3P8ZE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8010:KEF92 p03
gene id: 8010:KEF92_p03
uniprot id: Q85D49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8010:aurka
gene id: 8010:aurka
uniprot id: A0A3P8YUA8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

8010:tbx1
gene id: 8010:tbx1
uniprot id: A0A3P8XQD1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:chmp2ba
gene id: 8010:chmp2ba
uniprot id: A0A3P8XVK7
names: Similarity
messages: Belongs to the SNF7 family.

8010:sbk3
gene id: 8010:sbk3
uniprot id: A0A3P9A720
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:acss2
gene id: 8010:acss2
uniprot id: A0A3P8Y4A3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:mapre3b
gene id: 8010:mapre3b
uniprot id: A0A3P8XU83
uniprot id: A0A3P8ZPI6
uniprot id: A0A3P8ZPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8010:tpma
gene id: 8010:tpma
uniprot id: A0A3P8XGL9
uniprot id: A0A6Q2XVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8010:LOC106024670
gene id: 8010:LOC106024670
uniprot id: A0A3P8YMK0
names: Caution
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

8010:hoxb6a
gene id: 8010:hoxb6a
uniprot id: A0A6Q2Y024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:lhb
gene id: 8010:lhb
uniprot id: A0A3P9A1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8010:serpini1
gene id: 8010:serpini1
uniprot id: A0A3P8ZR11
names: Similarity
messages: Belongs to the serpin family.

8010:LOC105020848
gene id: 8010:LOC105020848
uniprot id: A0A3P8ZXW2
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8010:LOC105022192
gene id: 8010:LOC105022192
uniprot id: A0A3P8Z567
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8010:LOC105025831
gene id: 8010:LOC105025831
uniprot id: A0A3P9A868
names: Similarity
messages: Belongs to the myozenin family.

8010:rnf40
gene id: 8010:rnf40
uniprot id: A0A3P8XZE1
uniprot id: A0A3P8ZVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8010:LOC105027113
gene id: 8010:LOC105027113
uniprot id: A0A3P8ZE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8010:calca
gene id: 8010:calca
uniprot id: A0A3P8ZR72
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8010:june
gene id: 8010:june
uniprot id: A0A3P8YEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8010:LOC105029660
gene id: 8010:LOC105029660
uniprot id: A0A3P8ZV43
names: Caution
names: Similarity
messages: Belongs to the Ntn-hydrolase family.
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:fgd5a
gene id: 8010:fgd5a
uniprot id: A0A3P8ZLR6
names: Subcellular Location Annotation
messages: cytoskeleton

8010:asic1c
gene id: 8010:asic1c
uniprot id: A0A3P9AKS2
uniprot id: A0A6Q2ZGV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:mtmr11
gene id: 8010:mtmr11
uniprot id: A0A3P8Y5W0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8010:ppifa
gene id: 8010:ppifa
uniprot id: A0A3P9AQP3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:ip6k2b
gene id: 8010:ip6k2b
uniprot id: A0A3P8YLD6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:mettl4
gene id: 8010:mettl4
uniprot id: A0A3P8XTE3
names: Similarity
messages: Belongs to the MT-A70-like family.

8010:capzb
gene id: 8010:capzb
uniprot id: A0A3P8YB94
uniprot id: A0A3P9A2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8010:gemin2
gene id: 8010:gemin2
uniprot id: C1BYV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

8010:glrbb
gene id: 8010:glrbb
uniprot id: A0A3P8YY21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:gpcpd1
gene id: 8010:gpcpd1
uniprot id: A0A3P8Y9P7
uniprot id: A0A3P8YBV7
uniprot id: A0A3P9A190
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:mrs2
gene id: 8010:mrs2
uniprot id: A0A3P8ZI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

8010:si:ch211-129c21.1
gene id: 8010:si:ch211-129c21.1
uniprot id: A0A3P8YJ53
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105019762
gene id: 8010:LOC105019762
uniprot id: A0A3P8ZEX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8010:LOC105028791
gene id: 8010:LOC105028791
uniprot id: A0A3P8Z4Q9
names: Similarity
messages: Belongs to the angiomotin family.

8010:cd37
gene id: 8010:cd37
uniprot id: A0A3P8YXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:phkg1a
gene id: 8010:phkg1a
uniprot id: A0A3P8ZPQ4
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

8010:mrpl13
gene id: 8010:mrpl13
uniprot id: C1BX06
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8010:tgm1l1
gene id: 8010:tgm1l1
uniprot id: A0A3P8ZXE8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8010:LOC105029963
gene id: 8010:LOC105029963
uniprot id: A0A3P8YS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8010:si:ch1073-291c23.2
gene id: 8010:si:ch1073-291c23.2
uniprot id: A0A6Q2YNS7
uniprot id: C1BW04
names: Similarity
messages: Belongs to the MS4A family.

8010:LOC105017753
gene id: 8010:LOC105017753
uniprot id: A0A3P8XTI9
uniprot id: A0A3P8ZPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

8010:slc16a5a
gene id: 8010:slc16a5a
uniprot id: A0A3P8XZX9
names: Subcellular Location Annotation
messages: Membrane

8010:ddb1
gene id: 8010:ddb1
uniprot id: A0A3P8Z8J6
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105019167
gene id: 8010:LOC105019167
uniprot id: A0A3P8XX69
names: Similarity
messages: Belongs to the annexin family.

8010:LOC105016511
gene id: 8010:LOC105016511
uniprot id: A0A3P8ZH02
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8010:aprt
gene id: 8010:aprt
uniprot id: C1BWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

8010:supv3l1
gene id: 8010:supv3l1
uniprot id: A0A3P8YRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8010:impa2
gene id: 8010:impa2
uniprot id: A0A3P8XV97
uniprot id: A0A6Q2X5J1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8010:LOC105027617
gene id: 8010:LOC105027617
uniprot id: A0A3P8ZMF4
names: Similarity
messages: Belongs to the TMEM106 family.

8010:il17d
gene id: 8010:il17d
uniprot id: A0A3P8XLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8010:txnipb
gene id: 8010:txnipb
uniprot id: A0A3P8XUU8
names: Similarity
messages: Belongs to the arrestin family.

8010:kcnb1
gene id: 8010:kcnb1
uniprot id: A0A3P8XBK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

8010:LOC105009515
gene id: 8010:LOC105009515
uniprot id: A0A3P9A612
names: Subcellular Location Annotation
messages: Nucleus

8010:dmrta2
gene id: 8010:dmrta2
uniprot id: A0A3P8XVC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8010:txnrd2.2
gene id: 8010:txnrd2.2
uniprot id: A0A6Q2XM18
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

8010:nudt17
gene id: 8010:nudt17
uniprot id: A0A3P8XSQ0
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

8010:s1pr1
gene id: 8010:s1pr1
uniprot id: A0A3P8ZF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:cfap53
gene id: 8010:cfap53
uniprot id: A0A3P8Z932
names: Similarity
messages: Belongs to the CFAP53 family.

8010:LOC105020729
gene id: 8010:LOC105020729
uniprot id: A0A3P8ZVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:idua
gene id: 8010:idua
uniprot id: A0A3P8XVM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

8010:thrb
gene id: 8010:thrb
uniprot id: A0A3P8XX25
uniprot id: A0A3P8XYV2
uniprot id: A0A3P8ZSP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:ppme1
gene id: 8010:ppme1
uniprot id: A0A3P8ZT72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

8010:nup133
gene id: 8010:nup133
uniprot id: A0A3P8Y1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8010:kctd20
gene id: 8010:kctd20
uniprot id: A0A6Q2YC07
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105031496
gene id: 8010:LOC105031496
uniprot id: A0A3P8YVN2
names: Similarity
messages: Belongs to the peptidase C2 family.

8010:LOC105029586
gene id: 8010:LOC105029586
uniprot id: C1BXX8
names: Similarity
messages: Belongs to the HSBP1 family.

8010:LOC105022427
gene id: 8010:LOC105022427
uniprot id: A0A3P8YQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105022434
gene id: 8010:LOC105022434
uniprot id: A0A3P9ADS7
names: Similarity
messages: Belongs to the beta-catenin family.

8010:aldh3a2b
gene id: 8010:aldh3a2b
uniprot id: A0A3P8XK25
uniprot id: A0A3P8XMN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:barhl1a
gene id: 8010:barhl1a
uniprot id: A0A3P8ZSS1
names: Subcellular Location Annotation
messages: Nucleus

8010:si:dkeyp-69e1.8
gene id: 8010:si:dkeyp-69e1.8
uniprot id: A0A3P8ZV91
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:stat2
gene id: 8010:stat2
uniprot id: A0A3P9A6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8010:zgc:111976
gene id: 8010:zgc:111976
uniprot id: A0A3P8ZRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8010:LOC105023799
gene id: 8010:LOC105023799
uniprot id: A0A3P9A3F0
uniprot id: A0A3P9A3I4
names: Similarity
messages: Belongs to the copine family.

8010:slc25a1b
gene id: 8010:slc25a1b
uniprot id: A0A3P8XBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:blm
gene id: 8010:blm
uniprot id: A0A3P8YT96
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8010:LOC105016625
gene id: 8010:LOC105016625
uniprot id: A0A3P9AFR2
names: Similarity
messages: Belongs to the importin alpha family.

8010:dennd6b
gene id: 8010:dennd6b
uniprot id: A0A3P8Y692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

8010:arhgef1a
gene id: 8010:arhgef1a
uniprot id: A0A3P8YAQ5
uniprot id: A0A6Q2X429
names: Subcellular Location Annotation
messages: Cytoplasm

8010:metap1d
gene id: 8010:metap1d
uniprot id: A0A3P8XMY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8010:LOC105013757
gene id: 8010:LOC105013757
uniprot id: A0A3P8ZVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8010:cryba4
gene id: 8010:cryba4
uniprot id: A0A3P9AP31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8010:LOC109614553
gene id: 8010:LOC109614553
uniprot id: A0A3P8ZPZ8
names: Similarity
messages: Belongs to the serpin family.

8010:galnt7
gene id: 8010:galnt7
uniprot id: A0A3P8Y8Z9
uniprot id: A0A3P8YAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:myf5
gene id: 8010:myf5
uniprot id: A0A3P8ZDR3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8010:nup35
gene id: 8010:nup35
uniprot id: A0A3P9A1A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

8010:lrrfip2
gene id: 8010:lrrfip2
uniprot id: A0A3P8Y614
names: Similarity
messages: Belongs to the LRRFIP family.

8010:cavin4a
gene id: 8010:cavin4a
uniprot id: A0A3P9AA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

8010:eva1a
gene id: 8010:eva1a
uniprot id: A0A3P8YQA6
names: Similarity
messages: Belongs to the EVA1 family.

8010:fen1
gene id: 8010:fen1
uniprot id: A0A3P9AGU8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

8010:atad1a
gene id: 8010:atad1a
uniprot id: A0A3P8XRE2
uniprot id: A0A3P8XTR8
names: Similarity
messages: Belongs to the AAA ATPase family.

8010:mon2
gene id: 8010:mon2
uniprot id: A0A3P8XQC4
uniprot id: A0A3P8XSI1
names: Similarity
messages: Belongs to the MON2 family.

8010:LOC105006106
gene id: 8010:LOC105006106
uniprot id: A0A3P8XD68
names: Similarity
messages: Belongs to the AAA ATPase family.

8010:zdhhc3b
gene id: 8010:zdhhc3b
uniprot id: A0A3P8XNP1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:LOC105024890
gene id: 8010:LOC105024890
uniprot id: A0A3P8Y0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

8010:LOC105013096
gene id: 8010:LOC105013096
uniprot id: A0A3P9ALS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:lhx5
gene id: 8010:lhx5
uniprot id: A0A3P8XF28
names: Subcellular Location Annotation
messages: Nucleus

8010:vwc2
gene id: 8010:vwc2
uniprot id: A0A3P8YVG9
names: Subcellular Location Annotation
messages: Synapse

8010:p4hb
gene id: 8010:p4hb
uniprot id: A0A3P8XWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8010:nipsnap3a
gene id: 8010:nipsnap3a
uniprot id: A0A3P8Z6Q5
names: Similarity
messages: Belongs to the NipSnap family.

8010:rnaset2l
gene id: 8010:rnaset2l
uniprot id: A0A3P8Y2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

8010:LOC105019136
gene id: 8010:LOC105019136
uniprot id: A0A3P9AKY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105016987
gene id: 8010:LOC105016987
uniprot id: A0A3P9AGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:slc2a11l
gene id: 8010:slc2a11l
uniprot id: A0A3P8YSV8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:slc25a32a
gene id: 8010:slc25a32a
uniprot id: A0A3P8YFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:atp6v1f
gene id: 8010:atp6v1f
uniprot id: C1BXU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8010:pigc
gene id: 8010:pigc
uniprot id: A0A3P8XN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8010:sugp1
gene id: 8010:sugp1
uniprot id: A0A3P8ZRE5
names: Subcellular Location Annotation
messages: Nucleus

8010:renbp
gene id: 8010:renbp
uniprot id: A0A3P8XS19
uniprot id: A0A3P8ZPK4
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

8010:pigo
gene id: 8010:pigo
uniprot id: A0A3P8YRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:st6galnac6
gene id: 8010:st6galnac6
uniprot id: A0A3P8Z4V8
uniprot id: A0A3P8Z6Q2
uniprot id: A0A3P9AL44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:atp6ap1la
gene id: 8010:atp6ap1la
uniprot id: A0A3P8YYU7
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8010:epd
gene id: 8010:epd
uniprot id: P32188
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the ependymin family.
messages: Binds calcium through the terminal sialic acids.
messages: EPDs are synthesized in the meninx and secreted in the cerebrospinal fluid.
messages: Forms disulfide-linked dimers.
messages: May play a role in neural plasticity. May be involved during axon regeneration.
messages: Secreted

8010:camsap3
gene id: 8010:camsap3
uniprot id: A0A3P8ZYI2
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8010:LOC105020018
gene id: 8010:LOC105020018
uniprot id: C1BXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

8010:tfap2a
gene id: 8010:tfap2a
uniprot id: A0A3P8YWS1
uniprot id: A0A3P8YYL7
uniprot id: A0A3P9AFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

8010:cmtr1
gene id: 8010:cmtr1
uniprot id: A0A3P8XIJ1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

8010:tmtopsb
gene id: 8010:tmtopsb
uniprot id: A0A3P9A011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:zgc:158291
gene id: 8010:zgc:158291
uniprot id: A0A3P8ZKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:e2f1
gene id: 8010:e2f1
uniprot id: A0A3P9AC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:cenpo
gene id: 8010:cenpo
uniprot id: A0A3P9ADF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

8010:LOC105030613
gene id: 8010:LOC105030613
uniprot id: A0A6Q2ZFR3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8010:kcnh1b
gene id: 8010:kcnh1b
uniprot id: A0A3P8YP70
uniprot id: A0A3P8YP90
names: Subcellular Location Annotation
messages: Membrane

8010:slc7a9
gene id: 8010:slc7a9
uniprot id: A0A3P8YPI9
names: Subcellular Location Annotation
messages: Membrane

8010:fah
gene id: 8010:fah
uniprot id: A0A3P8ZC14
names: Similarity
messages: Belongs to the FAH family.

8010:fscn2a
gene id: 8010:fscn2a
uniprot id: A0A3P8YAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8010:sap18
gene id: 8010:sap18
uniprot id: A0A3P8ZLS4
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8010:endou2
gene id: 8010:endou2
uniprot id: A0A3P8Z9F9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8010:c4h4orf47
gene id: 8010:c4h4orf47
uniprot id: A0A3P8Y545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

8010:LOC105020624
gene id: 8010:LOC105020624
uniprot id: A0A3P8YNV8
uniprot id: A0A3P8YP07
uniprot id: A0A3P8YQX3
uniprot id: A0A3P9ABV7
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105006195
gene id: 8010:LOC105006195
uniprot id: A0A3P9ADM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8010:cltb
gene id: 8010:cltb
uniprot id: A0A3P9AFQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

8010:zgc:101744
gene id: 8010:zgc:101744
uniprot id: A0A3P8XVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8010:tbx5b
gene id: 8010:tbx5b
uniprot id: A0A3P8Y727
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:sdhaf3
gene id: 8010:sdhaf3
uniprot id: C1BZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

8010:xk
gene id: 8010:xk
uniprot id: A0A3P9ACD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:sema3ab
gene id: 8010:sema3ab
uniprot id: A0A3P9AGW8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:s100a10b
gene id: 8010:s100a10b
uniprot id: C1BXN9
names: Similarity
messages: Belongs to the S-100 family.

8010:pth3r
gene id: 8010:pth3r
uniprot id: A0A3P8Z905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8010:plpp2a
gene id: 8010:plpp2a
uniprot id: A0A6Q2ZCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8010:si:ch211-194m7.5
gene id: 8010:si:ch211-194m7.5
uniprot id: A0A3P8Y589
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:stc1l
gene id: 8010:stc1l
uniprot id: A0A3P8XNG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8010:LOC105009342
gene id: 8010:LOC105009342
uniprot id: A0A3P9ADZ7
names: Subcellular Location Annotation
messages: Secreted

8010:eaf2
gene id: 8010:eaf2
uniprot id: A0A3P8ZP23
names: Similarity
messages: Belongs to the EAF family.

8010:slc25a23b
gene id: 8010:slc25a23b
uniprot id: A0A3P9AP45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:LOC105019784
gene id: 8010:LOC105019784
uniprot id: A0A3P8XDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8010:LOC105011708
gene id: 8010:LOC105011708
uniprot id: A0A3P8XVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

8010:si:ch211-198n5.11
gene id: 8010:si:ch211-198n5.11
uniprot id: A0A3P8ZZ44
names: Similarity
messages: Belongs to the AccD/PCCB family.

8010:pigu
gene id: 8010:pigu
uniprot id: A0A3P8YTN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:gar1
gene id: 8010:gar1
uniprot id: A0A3P9AHR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

8010:esf1
gene id: 8010:esf1
uniprot id: A0A3P8Y4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

8010:LOC105014759
gene id: 8010:LOC105014759
uniprot id: A0A3P8X8Q4
uniprot id: A0A3P8XB90
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8010:mfsd8l1
gene id: 8010:mfsd8l1
uniprot id: A0A3P8ZM86
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105016429
gene id: 8010:LOC105016429
uniprot id: C1BWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

8010:LOC105022843
gene id: 8010:LOC105022843
uniprot id: A0A3P8ZZC2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8010:ndel1b
gene id: 8010:ndel1b
uniprot id: A0A3P8Y852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8010:tns1b
gene id: 8010:tns1b
uniprot id: A0A3P9AA21
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8010:dtx3l2.2
gene id: 8010:dtx3l2.2
uniprot id: A0A3P8YUX6
uniprot id: A0A3P8YW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8010:psme2
gene id: 8010:psme2
uniprot id: C1BZ00
names: Similarity
messages: Belongs to the PA28 family.

8010:LOC105028046
gene id: 8010:LOC105028046
uniprot id: A0A3P8YQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8010:LOC105021570
gene id: 8010:LOC105021570
uniprot id: A0A3P8YDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

8010:chrdl2
gene id: 8010:chrdl2
uniprot id: A0A3P8YU43
names: Subcellular Location Annotation
messages: Secreted

8010:cep57l1
gene id: 8010:cep57l1
uniprot id: A0A3P8YKU2
names: Similarity
messages: Belongs to the translokin family.

8010:eef1akmt1
gene id: 8010:eef1akmt1
uniprot id: A0A3P8ZLC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

8010:zgc:153169
gene id: 8010:zgc:153169
uniprot id: A0A3P9A4U5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8010:LOC105010114
gene id: 8010:LOC105010114
uniprot id: C1BW51
names: Similarity
messages: Belongs to the globin family.

8010:LOC105030533
gene id: 8010:LOC105030533
uniprot id: A0A3P8YY73
uniprot id: A0A3P9AG81
names: Subunit
messages: Homodimer.

8010:dkk2
gene id: 8010:dkk2
uniprot id: A0A3P8YKU6
names: Similarity
messages: Belongs to the dickkopf family.

8010:cdh5
gene id: 8010:cdh5
uniprot id: A0A3P9ACW7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

8010:gjd2b
gene id: 8010:gjd2b
uniprot id: A0A3P8XUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:aldh5a1
gene id: 8010:aldh5a1
uniprot id: A0A3P8ZTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

8010:ednrbb
gene id: 8010:ednrbb
uniprot id: A0A3P9A879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:prkci
gene id: 8010:prkci
uniprot id: A0A3P9A0M2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8010:LOC105017638
gene id: 8010:LOC105017638
uniprot id: A0A3P8XIR3
names: Similarity
messages: Belongs to the TENT family.

8010:ensab
gene id: 8010:ensab
uniprot id: A0A6Q2X0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8010:LOC105027913
gene id: 8010:LOC105027913
uniprot id: A0A3P9ANJ3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8010:LOC105015320
gene id: 8010:LOC105015320
uniprot id: A0A3P8XTN5
uniprot id: A0A3P8ZNP6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:zgc:174356
gene id: 8010:zgc:174356
uniprot id: A0A6Q2ZKJ5
names: Subcellular Location Annotation
messages: Membrane

8010:slc6a11b
gene id: 8010:slc6a11b
uniprot id: A0A3P8YGU0
uniprot id: A0A6Q2YCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:si:dkey-174m14.3
gene id: 8010:si:dkey-174m14.3
uniprot id: A0A3P8XTQ2
names: Subcellular Location Annotation
messages: Membrane

8010:dynll1
gene id: 8010:dynll1
uniprot id: C1BWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8010:apeh
gene id: 8010:apeh
uniprot id: A0A3P8Y3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

8010:uxt
gene id: 8010:uxt
uniprot id: C1BZI7
names: Similarity
messages: Belongs to the UXT family.

8010:aimp2
gene id: 8010:aimp2
uniprot id: A0A3P8XM75
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

8010:tsnax
gene id: 8010:tsnax
uniprot id: A0A6Q2ZI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

8010:LOC105028784
gene id: 8010:LOC105028784
uniprot id: C1BXD9
names: Similarity
messages: Belongs to the NipSnap family.

8010:ebag9
gene id: 8010:ebag9
uniprot id: A0A3P8Z0D4
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

8010:gipc2
gene id: 8010:gipc2
uniprot id: A0A6Q2ZLD9
names: Similarity
messages: Belongs to the GIPC family.

8010:slc29a3
gene id: 8010:slc29a3
uniprot id: A0A3P9A7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8010:LOC105023006
gene id: 8010:LOC105023006
uniprot id: A0A3P9AJY2
names: Subcellular Location Annotation
messages: Membrane

8010:arvcfb
gene id: 8010:arvcfb
uniprot id: A0A3P8XPN1
uniprot id: A0A3P8XQL1
uniprot id: A0A6Q2YFR4
names: Similarity
messages: Belongs to the beta-catenin family.

8010:LOC105011538
gene id: 8010:LOC105011538
uniprot id: C1BZP6
names: Similarity
messages: Belongs to the SPIN/STSY family.

8010:LOC105027762
gene id: 8010:LOC105027762
uniprot id: A0A3P8Y271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8010:LOC105015743
gene id: 8010:LOC105015743
uniprot id: A0A3P8ZC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:h3f3d
gene id: 8010:h3f3d
uniprot id: A0A3P9AEN1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:c1h19orf54
gene id: 8010:c1h19orf54
uniprot id: A0A3P9A4H2
names: Similarity
messages: Belongs to the UPF0692 family.

8010:mfn1b
gene id: 8010:mfn1b
uniprot id: A0A3P8XEZ5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8010:ranbp10
gene id: 8010:ranbp10
uniprot id: A0A3P8YL48
uniprot id: A0A3P8YLU3
names: Similarity
messages: Belongs to the RANBP9/10 family.

8010:LOC105025705
gene id: 8010:LOC105025705
uniprot id: A0A3P8XMI1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8010:mettl2a
gene id: 8010:mettl2a
uniprot id: A0A3P9AAZ7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8010:LOC105010654
gene id: 8010:LOC105010654
uniprot id: A0A3P8ZLC3
names: Similarity
messages: Belongs to the cullin family.

8010:LOC105019040
gene id: 8010:LOC105019040
uniprot id: C1BXS6
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8010:coq8aa
gene id: 8010:coq8aa
uniprot id: A0A3P9APU5
uniprot id: A0A6Q2ZI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

8010:adcy7
gene id: 8010:adcy7
uniprot id: A0A3P8XLX4
uniprot id: A0A3P8ZL62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8010:sumo3a
gene id: 8010:sumo3a
uniprot id: A0A3P8XXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8010:galnt13
gene id: 8010:galnt13
uniprot id: A0A3P8YIK3
uniprot id: A0A3P8YK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:glra2
gene id: 8010:glra2
uniprot id: A0A6Q2Z9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8010:zdhhc20a
gene id: 8010:zdhhc20a
uniprot id: A0A3P8YY76
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:LOC105017535
gene id: 8010:LOC105017535
uniprot id: A0A3P8ZYH6
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8010:nr2c2
gene id: 8010:nr2c2
uniprot id: A0A3P9AP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:dpt
gene id: 8010:dpt
uniprot id: A0A3P8XTS4
names: Similarity
messages: Belongs to the dermatopontin family.

8010:LOC105011881
gene id: 8010:LOC105011881
uniprot id: A0A3P8XCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8010:LOC105029077
gene id: 8010:LOC105029077
uniprot id: A0A3P8YHF5
names: Similarity
messages: Belongs to the CDI family.

8010:LOC105009239
gene id: 8010:LOC105009239
uniprot id: A0A6Q2XL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8010:LOC105011434
gene id: 8010:LOC105011434
uniprot id: A0A3P8XCA1
uniprot id: A0A3P8ZD87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:fcer1g
gene id: 8010:fcer1g
uniprot id: A0A3P8YWF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105009536
gene id: 8010:LOC105009536
uniprot id: A0A3P8XHG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:gdap2
gene id: 8010:gdap2
uniprot id: A0A3P8XNN5
uniprot id: A0A3P8ZJP1
uniprot id: A0A6Q2XMX0
uniprot id: A0A6Q2ZMQ7
names: Similarity
messages: Belongs to the GDAP2 family.

8010:usp45
gene id: 8010:usp45
uniprot id: A0A3P9AJI5
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:akr1a1b
gene id: 8010:akr1a1b
uniprot id: C1BY49
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8010:LOC105011766
gene id: 8010:LOC105011766
uniprot id: A0A3P8ZEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8010:cdca9
gene id: 8010:cdca9
uniprot id: A0A3P9AE15
names: Similarity
messages: Belongs to the borealin family.

8010:limk2
gene id: 8010:limk2
uniprot id: A0A3P8YA91
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8010:soul5
gene id: 8010:soul5
uniprot id: C1BY95
names: Similarity
messages: Belongs to the HEBP family.

8010:LOC105025871
gene id: 8010:LOC105025871
uniprot id: A0A3P9AKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8010:pdha1a
gene id: 8010:pdha1a
uniprot id: A0A3P8Z058
uniprot id: A0A3P8Z059
uniprot id: A0A3P9AIZ6
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

8010:LOC105025762
gene id: 8010:LOC105025762
uniprot id: A0A3P8ZQZ3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:adam22
gene id: 8010:adam22
uniprot id: A0A6Q2YTN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:fli1
gene id: 8010:fli1
uniprot id: A0A3P8YPT8
uniprot id: A0A3P8YPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:vcp
gene id: 8010:vcp
uniprot id: A0A3P8ZY14
names: Similarity
messages: Belongs to the AAA ATPase family.

8010:KEF92 p06
gene id: 8010:KEF92_p06
uniprot id: Q85D52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

8010:tecpr1b
gene id: 8010:tecpr1b
uniprot id: A0A3P8XMJ1
names: Similarity
messages: Belongs to the TECPR1 family.

8010:LOC105020258
gene id: 8010:LOC105020258
uniprot id: A0A3P8ZQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:phf8
gene id: 8010:phf8
uniprot id: A0A3P8ZT48
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8010:LOC105021682
gene id: 8010:LOC105021682
uniprot id: A0A3P9A700
uniprot id: A0A6Q2X4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:nrn1la
gene id: 8010:nrn1la
uniprot id: A0A3P9A842
names: Similarity
messages: Belongs to the neuritin family.

8010:b4galt6
gene id: 8010:b4galt6
uniprot id: A0A3P8X896
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8010:nt5dc1
gene id: 8010:nt5dc1
uniprot id: A0A3P9AAG3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8010:fitm1
gene id: 8010:fitm1
uniprot id: A0A3P9A8U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

8010:shhb
gene id: 8010:shhb
uniprot id: A0A3P8YBZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8010:smim15
gene id: 8010:smim15
uniprot id: A0A3P8XC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

8010:LOC105010804
gene id: 8010:LOC105010804
uniprot id: A0A3P9API0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8010:ppardb
gene id: 8010:ppardb
uniprot id: A0A6Q2YCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:LOC105030733
gene id: 8010:LOC105030733
uniprot id: A0A3P8XYX0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8010:LOC105021740
gene id: 8010:LOC105021740
uniprot id: A0A3P8YPW4
uniprot id: A0A3P8YQ29
uniprot id: A0A3P9AC31
uniprot id: A0A3P9ACA2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:fscn2b
gene id: 8010:fscn2b
uniprot id: A0A3P8YMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8010:LOC105030128
gene id: 8010:LOC105030128
uniprot id: A0A3P8XJI7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8010:LOC105007917
gene id: 8010:LOC105007917
uniprot id: A0A3P8XY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

8010:apoea
gene id: 8010:apoea
uniprot id: C1BX75
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8010:sypl1
gene id: 8010:sypl1
uniprot id: A0A3P8YLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8010:LOC105014386
gene id: 8010:LOC105014386
uniprot id: A0A3P8ZHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:gpr183a
gene id: 8010:gpr183a
uniprot id: A0A3P8Y5U7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105010768
gene id: 8010:LOC105010768
uniprot id: A0A3P8ZYT1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105029764
gene id: 8010:LOC105029764
uniprot id: A0A3P8XPQ0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8010:LOC105028922
gene id: 8010:LOC105028922
uniprot id: A0A3P8ZB31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8010:tac3a
gene id: 8010:tac3a
uniprot id: A0A3P8XVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

8010:stard3
gene id: 8010:stard3
uniprot id: A0A3P8YNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8010:tm2d2
gene id: 8010:tm2d2
uniprot id: A0A3P8XJ21
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105015382
gene id: 8010:LOC105015382
uniprot id: A0A3P8YXT2
names: Similarity
messages: Belongs to the MAP7 family.

8010:ndufa10
gene id: 8010:ndufa10
uniprot id: A0A3P8XFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

8010:pomt1
gene id: 8010:pomt1
uniprot id: A0A3P8YGE7
uniprot id: A0A3P9A6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

8010:dgat1b
gene id: 8010:dgat1b
uniprot id: A0A3P8ZIW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8010:grin2ca
gene id: 8010:grin2ca
uniprot id: A0A3P8YQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8010:trim32
gene id: 8010:trim32
uniprot id: A0A3P8YEH3
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8010:LOC105019632
gene id: 8010:LOC105019632
uniprot id: C1BXY8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8010:napba
gene id: 8010:napba
uniprot id: A0A3P8Y9J2
uniprot id: A0A6Q2Y4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8010:idnk
gene id: 8010:idnk
uniprot id: C1BXE9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

8010:acvr2ba
gene id: 8010:acvr2ba
uniprot id: A0A3P9ACC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:LOC105024420
gene id: 8010:LOC105024420
uniprot id: A0A3P8XI45
uniprot id: A0A6Q2Z0V2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8010:LOC105005606
gene id: 8010:LOC105005606
uniprot id: A0A3P9A1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:skor2
gene id: 8010:skor2
uniprot id: A0A3P9A191
names: Similarity
messages: Belongs to the SKI family.

8010:slc2a3b
gene id: 8010:slc2a3b
uniprot id: A0A3P8YJA7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:slc28a1
gene id: 8010:slc28a1
uniprot id: A0A3P8YSL4
uniprot id: A0A6Q2XA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

8010:unc119.1
gene id: 8010:unc119.1
uniprot id: A0A3P8Z6Q4
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8010:slc1a7a
gene id: 8010:slc1a7a
uniprot id: A0A3P9A037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:cdk1
gene id: 8010:cdk1
uniprot id: C1BWE3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105017597
gene id: 8010:LOC105017597
uniprot id: A0A3P8ZGT5
names: Subcellular Location Annotation
messages: Nucleus

8010:pdcd10
gene id: 8010:pdcd10
uniprot id: C1BXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8010:cldnk
gene id: 8010:cldnk
uniprot id: A0A3P8Y1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:borcs5
gene id: 8010:borcs5
uniprot id: A0A3P8Y2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

8010:scamp2
gene id: 8010:scamp2
uniprot id: A0A3P8ZEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8010:slc4a1a
gene id: 8010:slc4a1a
uniprot id: A0A3P8Z3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8010:slc12a7b
gene id: 8010:slc12a7b
uniprot id: A0A3P8Z6S2
uniprot id: A0A3P8Z6S7
uniprot id: A0A3P8Z8C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8010:atp6v1ba
gene id: 8010:atp6v1ba
uniprot id: A0A3P9A353
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

8010:cpne4b
gene id: 8010:cpne4b
uniprot id: A0A3P8ZEZ8
names: Similarity
messages: Belongs to the copine family.

8010:LOC105023195
gene id: 8010:LOC105023195
uniprot id: A0A3P9AI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8010:LOC105028706
gene id: 8010:LOC105028706
uniprot id: A0A3P8YWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8010:LOC105021931
gene id: 8010:LOC105021931
uniprot id: A0A3P8Z6R3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:b4galt2
gene id: 8010:b4galt2
uniprot id: A0A3P8ZYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8010:LOC105015412
gene id: 8010:LOC105015412
uniprot id: A0A3P9ABW2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8010:itga11a
gene id: 8010:itga11a
uniprot id: A0A3P9AKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:LOC105025824
gene id: 8010:LOC105025824
uniprot id: A0A3P9A7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:stx16
gene id: 8010:stx16
uniprot id: A0A3P9AJ62
names: Similarity
messages: Belongs to the syntaxin family.

8010:bpifcl
gene id: 8010:bpifcl
uniprot id: A0A3P8YAQ8
uniprot id: A0A3P9A1Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8010:tor2a
gene id: 8010:tor2a
uniprot id: A0A3P9A661
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8010:ar
gene id: 8010:ar
uniprot id: A0A3P8Y2H9
uniprot id: A0A3P8ZWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:taf11
gene id: 8010:taf11
uniprot id: A0A3P8YUY2
names: Similarity
messages: Belongs to the TAF11 family.

8010:si:ch211-132p1.2
gene id: 8010:si:ch211-132p1.2
uniprot id: A0A3P9AI81
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:slx1b
gene id: 8010:slx1b
uniprot id: A0A6Q2ZM26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105024540
gene id: 8010:LOC105024540
uniprot id: C1BW47
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8010:meis3
gene id: 8010:meis3
uniprot id: A0A3P9AG80
uniprot id: A0A6Q2XPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:LOC105016654
gene id: 8010:LOC105016654
uniprot id: A0A3P8YMW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:npr1b
gene id: 8010:npr1b
uniprot id: A0A3P8XUB9
uniprot id: A0A3P8ZSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8010:zdhhc14
gene id: 8010:zdhhc14
uniprot id: A0A3P9A2G7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:frg1
gene id: 8010:frg1
uniprot id: A0A3P9AIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

8010:mapk6
gene id: 8010:mapk6
uniprot id: A0A3P8YW07
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8010:armc8
gene id: 8010:armc8
uniprot id: A0A3P8ZKF1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:amdhd1
gene id: 8010:amdhd1
uniprot id: A0A3P8ZEC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

8010:si:ch211-106h11.3
gene id: 8010:si:ch211-106h11.3
uniprot id: A0A3P8ZVZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:napbb
gene id: 8010:napbb
uniprot id: A0A3P8YC44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8010:mipb
gene id: 8010:mipb
uniprot id: A0A3P8YGY5
uniprot id: A0A6Q2YVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8010:LOC105010945
gene id: 8010:LOC105010945
uniprot id: A0A3P8ZA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:atp5f1b
gene id: 8010:atp5f1b
uniprot id: A0A3P9AKI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8010:mrm2
gene id: 8010:mrm2
uniprot id: C1BZC0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

8010:nsun3
gene id: 8010:nsun3
uniprot id: A0A3P8XEE6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8010:kiaa1191
gene id: 8010:kiaa1191
uniprot id: A0A3P9APG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

8010:ppp1r14ab
gene id: 8010:ppp1r14ab
uniprot id: A0A3P8Y281
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8010:LOC105024844
gene id: 8010:LOC105024844
uniprot id: A0A3P8ZI14
names: Similarity
messages: Belongs to the BRINP family.

8010:dis3l2
gene id: 8010:dis3l2
uniprot id: A0A3P8Z6R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

8010:fdft1
gene id: 8010:fdft1
uniprot id: A0A3P8Y5Z8
uniprot id: A0A3P8Y617
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

8010:mrpl20
gene id: 8010:mrpl20
uniprot id: C1BZT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8010:pdf
gene id: 8010:pdf
uniprot id: A0A3P8Y881
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

8010:epgn
gene id: 8010:epgn
uniprot id: C1BZ37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105013975
gene id: 8010:LOC105013975
uniprot id: A0A3P9ALT5
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

8010:pfn1
gene id: 8010:pfn1
uniprot id: A0A6Q2XLW9
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

8010:cpm
gene id: 8010:cpm
uniprot id: A0A3P8YA44
uniprot id: A0A3P8YAE4
names: Similarity
messages: Belongs to the peptidase M14 family.

8010:LOC105020518
gene id: 8010:LOC105020518
uniprot id: A0A3P8YFH3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:slc16a3
gene id: 8010:slc16a3
uniprot id: A0A3P8YK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8010:sec24b
gene id: 8010:sec24b
uniprot id: A0A3P9AKL7
uniprot id: A0A3P9ALP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8010:trappc6b
gene id: 8010:trappc6b
uniprot id: A0A3P8XSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8010:LOC105026822
gene id: 8010:LOC105026822
uniprot id: A0A3P9ABV3
uniprot id: A0A3P9ABZ1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8010:foxl3
gene id: 8010:foxl3
uniprot id: A0A6Q2ZQY7
names: Subcellular Location Annotation
messages: Nucleus

8010:chd8
gene id: 8010:chd8
uniprot id: A0A3P8ZGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: Component of some MLL1/MLL complex.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. May also act as a transcription activator by participating in efficient U6 RNA polymerase III transcription.
messages: Nucleus

8010:cryba2b
gene id: 8010:cryba2b
uniprot id: A0A3P8YEN4
uniprot id: A0A3P9A4B4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:atp5pb
gene id: 8010:atp5pb
uniprot id: C1BWV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8010:fam83e
gene id: 8010:fam83e
uniprot id: A0A3P8Z7I7
names: Similarity
messages: Belongs to the FAM83 family.

8010:kcna4
gene id: 8010:kcna4
uniprot id: A0A3P8Z9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

8010:c10h18orf21
gene id: 8010:c10h18orf21
uniprot id: A0A3P9AI09
names: Similarity
messages: Belongs to the UPF0711 family.

8010:pvalb8
gene id: 8010:pvalb8
uniprot id: A0A3P8XQY1
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8010:kctd3
gene id: 8010:kctd3
uniprot id: A0A3P8ZDC2
names: Similarity
messages: Belongs to the KCTD3 family.

8010:LOC105028601
gene id: 8010:LOC105028601
uniprot id: A0A3P9AHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

8010:LOC105019500
gene id: 8010:LOC105019500
uniprot id: A0A3P8Z499
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

8010:irx4b
gene id: 8010:irx4b
uniprot id: A0A3P8Z966
names: Subcellular Location Annotation
messages: Nucleus

8010:cnih3
gene id: 8010:cnih3
uniprot id: A0A3P8ZG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8010:klhl22
gene id: 8010:klhl22
uniprot id: A0A3P8YQJ3
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

8010:slc7a4
gene id: 8010:slc7a4
uniprot id: A0A3P8Z4D5
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105017645
gene id: 8010:LOC105017645
uniprot id: A0A3P8XJW2
names: Similarity
messages: Belongs to the proline racemase family.

8010:siah2l
gene id: 8010:siah2l
uniprot id: A0A3P8XKA2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8010:msx2b
gene id: 8010:msx2b
uniprot id: A0A6Q2XJV3
names: Subcellular Location Annotation
messages: Nucleus

8010:yy1a
gene id: 8010:yy1a
uniprot id: A0A3P8YJA1
names: Similarity
messages: Belongs to the YY transcription factor family.

8010:chmp2bb
gene id: 8010:chmp2bb
uniprot id: A0A3P8XA75
names: Similarity
messages: Belongs to the SNF7 family.

8010:znf711
gene id: 8010:znf711
uniprot id: A0A3P8XIF8
names: Subcellular Location Annotation
messages: Nucleus

8010:csnk1db
gene id: 8010:csnk1db
uniprot id: A0A3P9A8U0
uniprot id: A0A3P9A928
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:chmp1b
gene id: 8010:chmp1b
uniprot id: A0A3P8XZ35
names: Similarity
messages: Belongs to the SNF7 family.

8010:polr1c
gene id: 8010:polr1c
uniprot id: A0A3P9A1F7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

8010:map4k2
gene id: 8010:map4k2
uniprot id: A0A6Q2XJV7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8010:psmf1
gene id: 8010:psmf1
uniprot id: A0A3P8Z195
uniprot id: C1BYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

8010:hscb
gene id: 8010:hscb
uniprot id: C1BWA0
names: Similarity
messages: Belongs to the HscB family.

8010:si:dkey-202l22.3
gene id: 8010:si:dkey-202l22.3
uniprot id: A0A3P8Y9P9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:ptp4a2b
gene id: 8010:ptp4a2b
uniprot id: A0A3P8XIY6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8010:wrn
gene id: 8010:wrn
uniprot id: A0A3P9ABA2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8010:hoxa13b
gene id: 8010:hoxa13b
uniprot id: A0A3P8XUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:KEF92 p07
gene id: 8010:KEF92_p07
uniprot id: Q85D53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8010:LOC105013902
gene id: 8010:LOC105013902
uniprot id: A0A3P8XFV8
names: Subcellular Location Annotation
messages: Membrane

8010:hsd3b1
gene id: 8010:hsd3b1
uniprot id: A0A3P8XKH8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8010:hnrnpk
gene id: 8010:hnrnpk
uniprot id: A0A3P8XE51
names: Subcellular Location Annotation
messages: nucleoplasm

8010:tmem147
gene id: 8010:tmem147
uniprot id: C1BYB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:slc16a9b
gene id: 8010:slc16a9b
uniprot id: A0A3P8YMX7
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105030282
gene id: 8010:LOC105030282
uniprot id: A0A3P8ZT96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:eif4a3
gene id: 8010:eif4a3
uniprot id: C1BZ96
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:LOC105026259
gene id: 8010:LOC105026259
uniprot id: A0A3P8Z9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

8010:bop1
gene id: 8010:bop1
uniprot id: A0A3P8Z2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8010:atp2a1l
gene id: 8010:atp2a1l
uniprot id: A0A3P9AM00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8010:grcc10
gene id: 8010:grcc10
uniprot id: A0A3P8ZST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

8010:svilc
gene id: 8010:svilc
uniprot id: A0A3P8YK37
uniprot id: A0A3P8YKX6
uniprot id: A0A3P9A806
names: Similarity
messages: Belongs to the villin/gelsolin family.

8010:pde5ab
gene id: 8010:pde5ab
uniprot id: A0A3P8Y604
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:slc31a1
gene id: 8010:slc31a1
uniprot id: A0A3P8XPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

8010:LOC105015303
gene id: 8010:LOC105015303
uniprot id: A0A3P8XQD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8010:rpl8
gene id: 8010:rpl8
uniprot id: A0A3P8Z9C2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8010:lactb2
gene id: 8010:lactb2
uniprot id: A0A3P8XWE5
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

8010:si:ch1073-513e17.1
gene id: 8010:si:ch1073-513e17.1
uniprot id: A0A3P9ANQ5
names: Subcellular Location Annotation
messages: Membrane

8010:tnfaip2a
gene id: 8010:tnfaip2a
uniprot id: A0A3P8YPF2
uniprot id: A0A3P8YQK5
names: Similarity
messages: Belongs to the SEC6 family.

8010:max
gene id: 8010:max
uniprot id: A0A6Q2XSP1
uniprot id: C1BYF6
names: Similarity
messages: Belongs to the MAX family.

8010:ism1
gene id: 8010:ism1
uniprot id: A0A3P9A8Y5
names: Similarity
messages: Belongs to the isthmin family.

8010:LOC105024746
gene id: 8010:LOC105024746
uniprot id: A0A3P8XGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:cldn7a
gene id: 8010:cldn7a
uniprot id: A0A3P8Z677
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:trip10a
gene id: 8010:trip10a
uniprot id: A0A3P8ZAH2
uniprot id: A0A3P8ZB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

8010:LOC105024506
gene id: 8010:LOC105024506
uniprot id: A0A3P8YQV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105030125
gene id: 8010:LOC105030125
uniprot id: A0A3P8Z726
uniprot id: A0A3P8Z737
uniprot id: A0A3P9AN37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8010:LOC105014003
gene id: 8010:LOC105014003
uniprot id: A0A3P8YJ22
uniprot id: A0A3P9A5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

8010:ccn1l1
gene id: 8010:ccn1l1
uniprot id: A0A3P8YWC8
names: Caution
names: Similarity
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:syn1
gene id: 8010:syn1
uniprot id: A0A3P8YT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synapsin family.
messages: Golgi apparatus
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: synaptic vesicle

8010:LOC105017357
gene id: 8010:LOC105017357
uniprot id: A0A3P8ZHS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8010:aco2
gene id: 8010:aco2
uniprot id: A0A3P9AFS7
uniprot id: A0A6Q2XUN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

8010:LOC105008767
gene id: 8010:LOC105008767
uniprot id: A0A3P8XFK1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:myod1
gene id: 8010:myod1
uniprot id: A0A3P8ZMW6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8010:nlk2
gene id: 8010:nlk2
uniprot id: A0A3P8YI18
uniprot id: A0A6Q2YBP9
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8010:si:dkey-5i3.5
gene id: 8010:si:dkey-5i3.5
uniprot id: A0A3P8XAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8010:fgf3
gene id: 8010:fgf3
uniprot id: A0A3P8Z0Q6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:tbr1b
gene id: 8010:tbr1b
uniprot id: A0A3P9ADQ0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:rpl6
gene id: 8010:rpl6
uniprot id: A0A3P8ZTB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

8010:LOC105027696
gene id: 8010:LOC105027696
uniprot id: A0A3P8Z063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8010:upf3a
gene id: 8010:upf3a
uniprot id: A0A6Q2WWJ2
names: Similarity
messages: Belongs to the RENT3 family.

8010:LOC105019373
gene id: 8010:LOC105019373
uniprot id: A0A3P8ZMJ5
uniprot id: A0A6Q2XGL8
names: Subcellular Location Annotation
messages: Secreted

8010:LOC105013572
gene id: 8010:LOC105013572
uniprot id: A0A3P8XJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8010:atp5if1a
gene id: 8010:atp5if1a
uniprot id: C1BWJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8010:LOC105023158
gene id: 8010:LOC105023158
uniprot id: A0A3P8XCF8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:lsm6
gene id: 8010:lsm6
uniprot id: C1BYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

8010:vps33b
gene id: 8010:vps33b
uniprot id: A0A3P8X9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8010:anxa1a
gene id: 8010:anxa1a
uniprot id: A0A3P8ZCQ6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: cilium

8010:LOC105023987
gene id: 8010:LOC105023987
uniprot id: A0A3P8YB49
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:slco2a1
gene id: 8010:slco2a1
uniprot id: A0A3P8ZN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8010:LOC105026155
gene id: 8010:LOC105026155
uniprot id: A0A3P9AEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

8010:oprm1
gene id: 8010:oprm1
uniprot id: A0A3P8YDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

8010:cenpt
gene id: 8010:cenpt
uniprot id: A0A3P8ZYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus

8010:vps25
gene id: 8010:vps25
uniprot id: A0A3P9A4Y8
names: Similarity
messages: Belongs to the VPS25 family.

8010:map3k5
gene id: 8010:map3k5
uniprot id: A0A3P8YTG5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8010:pdhx
gene id: 8010:pdhx
uniprot id: A0A3P8XEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

8010:sfrp5
gene id: 8010:sfrp5
uniprot id: A0A3P8Z390
uniprot id: A0A3P9AKB7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105016843
gene id: 8010:LOC105016843
uniprot id: A0A3P8XQB6
names: Similarity
messages: Belongs to the SZRD1 family.

8010:mpp5a
gene id: 8010:mpp5a
uniprot id: A0A3P9AP67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

8010:vps53
gene id: 8010:vps53
uniprot id: A0A3P8ZPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8010:LOC105019183
gene id: 8010:LOC105019183
uniprot id: A0A3P8ZA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:slc25a24
gene id: 8010:slc25a24
uniprot id: A0A3P8Z814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:LOC105022174
gene id: 8010:LOC105022174
uniprot id: A0A3P8Z6R4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:evx1
gene id: 8010:evx1
uniprot id: A0A3P8XHG5
names: Subcellular Location Annotation
messages: Nucleus

8010:rps6ka1
gene id: 8010:rps6ka1
uniprot id: A0A3P8YF10
uniprot id: A0A3P9A5N5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8010:acd
gene id: 8010:acd
uniprot id: A0A3P8Y4A5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

8010:LOC105026070
gene id: 8010:LOC105026070
uniprot id: A0A3P8Z841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

8010:pdgfbb
gene id: 8010:pdgfbb
uniprot id: A0A3P8Y0P1
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8010:ehd4
gene id: 8010:ehd4
uniprot id: A0A3P8ZGL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8010:ogt.1
gene id: 8010:ogt.1
uniprot id: A0A3P8ZHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

8010:btc
gene id: 8010:btc
uniprot id: A0A3P8X7Y6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:eya1
gene id: 8010:eya1
uniprot id: A0A3P8XT26
uniprot id: A0A3P8ZPI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8010:nr4a1
gene id: 8010:nr4a1
uniprot id: A0A3P8ZEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:soga1
gene id: 8010:soga1
uniprot id: A0A3P8ZWI8
names: Similarity
messages: Belongs to the SOGA family.

8010:LOC105013829
gene id: 8010:LOC105013829
uniprot id: A0A3P8XMY9
uniprot id: A0A6Q2ZJD9
names: Subcellular Location Annotation
messages: Membrane

8010:il2rb
gene id: 8010:il2rb
uniprot id: A0A3P8Y1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane

8010:thoc7
gene id: 8010:thoc7
uniprot id: A0A3P8XR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

8010:eif3s6ip
gene id: 8010:eif3s6ip
uniprot id: A0A3P8ZUT1
uniprot id: A0A6Q2YWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8010:slc9a6b
gene id: 8010:slc9a6b
uniprot id: A0A3P8XI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

8010:crx
gene id: 8010:crx
uniprot id: A0A3P8YMH8
names: Subcellular Location Annotation
messages: Nucleus

8010:asic2
gene id: 8010:asic2
uniprot id: A0A3P8Z486
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:znf687a
gene id: 8010:znf687a
uniprot id: A0A3P8Y1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

8010:mogat3b
gene id: 8010:mogat3b
uniprot id: A0A3P8XM31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:pth1r
gene id: 8010:pth1r
uniprot id: A0A3P8Z7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8010:cnrip1b
gene id: 8010:cnrip1b
uniprot id: A0A3P9A451
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8010:sst1.2
gene id: 8010:sst1.2
uniprot id: A0A6Q2Z1B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8010:wif1
gene id: 8010:wif1
uniprot id: A0A3P8Y5G7
uniprot id: A0A3P8Y796
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:tmlhe
gene id: 8010:tmlhe
uniprot id: A0A6Q2ZNX7
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

8010:ap3s2
gene id: 8010:ap3s2
uniprot id: A0A3P9A8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8010:sbds
gene id: 8010:sbds
uniprot id: A0A6Q2YF58
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

8010:cers6
gene id: 8010:cers6
uniprot id: A0A3P9AFU3
uniprot id: A0A3P9AGZ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:sgk2a
gene id: 8010:sgk2a
uniprot id: A0A3P8YAK6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:pgr
gene id: 8010:pgr
uniprot id: A0A3P9APG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:psmb2
gene id: 8010:psmb2
uniprot id: A0A3P9AP00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8010:taf5l
gene id: 8010:taf5l
uniprot id: A0A3P8Y1I9
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8010:itpkca
gene id: 8010:itpkca
uniprot id: A0A3P8ZSR3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:LOC105008983
gene id: 8010:LOC105008983
uniprot id: A0A3P8Y116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8010:sh3bp5a
gene id: 8010:sh3bp5a
uniprot id: A0A3P8XEB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8010:slc39a14
gene id: 8010:slc39a14
uniprot id: A0A3P8ZLI2
names: Subcellular Location Annotation
messages: Membrane

8010:tbx19
gene id: 8010:tbx19
uniprot id: A0A3P8X7H6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:atpaf2
gene id: 8010:atpaf2
uniprot id: A0A3P9ABM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

8010:hpda
gene id: 8010:hpda
uniprot id: A0A3P8YWY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8010:LOC105024525
gene id: 8010:LOC105024525
uniprot id: A0A3P8Y3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8010:ero1b
gene id: 8010:ero1b
uniprot id: A0A3P8YFE7
uniprot id: A0A3P8YG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

8010:LOC105011357
gene id: 8010:LOC105011357
uniprot id: A0A3P8ZHU3
names: Similarity
messages: Belongs to the GADD45 family.

8010:LOC105028052
gene id: 8010:LOC105028052
uniprot id: A0A3P8YQY1
names: Similarity
messages: Belongs to the MHC class I family.

8010:lamc3
gene id: 8010:lamc3
uniprot id: A0A3P8XCK3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8010:samm50
gene id: 8010:samm50
uniprot id: A0A3P8XBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

8010:acta1a
gene id: 8010:acta1a
uniprot id: A0A3P8XLX6
names: Similarity
messages: Belongs to the actin family.

8010:pfkpa
gene id: 8010:pfkpa
uniprot id: A0A3P8XBP1
uniprot id: A0A3P8ZG45
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:susd2
gene id: 8010:susd2
uniprot id: A0A3P8ZIT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:rps5
gene id: 8010:rps5
uniprot id: C1BYE1
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8010:LOC105014583
gene id: 8010:LOC105014583
uniprot id: A0A3P8YYG7
uniprot id: A0A3P9AHM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:galnt12
gene id: 8010:galnt12
uniprot id: A0A3P9AI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:aplnr2
gene id: 8010:aplnr2
uniprot id: A0A3P9AKV7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:hoxa2b
gene id: 8010:hoxa2b
uniprot id: A0A3P8XUP7
names: Subcellular Location Annotation
messages: Nucleus

8010:ces3
gene id: 8010:ces3
uniprot id: A0A3P9A2V8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8010:ndufa6
gene id: 8010:ndufa6
uniprot id: A0A6Q2YB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:mzt2b
gene id: 8010:mzt2b
uniprot id: A0A3P8ZF96
uniprot id: A0A3P8ZGE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

8010:aldh8a1
gene id: 8010:aldh8a1
uniprot id: A0A3P8ZLY3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:LOC105010681
gene id: 8010:LOC105010681
uniprot id: A0A3P8ZTD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105010801
gene id: 8010:LOC105010801
uniprot id: A0A3P8XQH9
names: Similarity
messages: Belongs to the DSH family.

8010:cdc42ep1b
gene id: 8010:cdc42ep1b
uniprot id: A0A3P8ZPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8010:tpi1b
gene id: 8010:tpi1b
uniprot id: A0A3P8YS25
uniprot id: C1BYQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8010:LOC105029768
gene id: 8010:LOC105029768
uniprot id: C1BYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8010:pde8b
gene id: 8010:pde8b
uniprot id: A0A3P8ZLT3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:suz12b
gene id: 8010:suz12b
uniprot id: A0A3P8ZLL9
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8010:dnah7
gene id: 8010:dnah7
uniprot id: A0A3P8ZV56
names: Similarity
messages: Belongs to the dynein heavy chain family.

8010:dis3
gene id: 8010:dis3
uniprot id: A0A3P8X8F0
names: Similarity
messages: Belongs to the RNR ribonuclease family.

8010:ddit3
gene id: 8010:ddit3
uniprot id: A0A3P8XZW4
uniprot id: A0A3P8ZUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8010:cnr2
gene id: 8010:cnr2
uniprot id: A0A3P8YLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC109614588
gene id: 8010:LOC109614588
uniprot id: A0A3P8X798
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:nsg2
gene id: 8010:nsg2
uniprot id: A0A3P9ALE9
names: Similarity
messages: Belongs to the NSG family.

8010:il15
gene id: 8010:il15
uniprot id: A0A3P9A516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

8010:glmp
gene id: 8010:glmp
uniprot id: A0A3P9A8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

8010:atf4b
gene id: 8010:atf4b
uniprot id: A0A3P8Y0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8010:ccng2
gene id: 8010:ccng2
uniprot id: A0A3P8YH33
names: Similarity
messages: Belongs to the cyclin family.

8010:si:ch211-127i16.2
gene id: 8010:si:ch211-127i16.2
uniprot id: A0A3P8YNG8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8010:LOC105005795
gene id: 8010:LOC105005795
uniprot id: A0A3P8ZXB0
uniprot id: A0A6Q2X1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

8010:LOC105015688
gene id: 8010:LOC105015688
uniprot id: A0A3P8ZLY8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:mmd
gene id: 8010:mmd
uniprot id: A0A3P8YQ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:ptgir
gene id: 8010:ptgir
uniprot id: A0A3P9A306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:gng8
gene id: 8010:gng8
uniprot id: A0A3P9AEW2
uniprot id: A0A6Q2ZLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:yrk
gene id: 8010:yrk
uniprot id: A0A3P8ZCR1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:garem
gene id: 8010:garem
uniprot id: A0A3P9A8I5
names: Similarity
messages: Belongs to the GAREM family.

8010:slc41a2b
gene id: 8010:slc41a2b
uniprot id: A0A3P8XIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8010:zgc:165520
gene id: 8010:zgc:165520
uniprot id: A0A3P9AFV2
names: Similarity
messages: Belongs to the syntaxin family.

8010:si:dkey-6i22.5
gene id: 8010:si:dkey-6i22.5
uniprot id: C1BZ28
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

8010:cpn1
gene id: 8010:cpn1
uniprot id: A0A3P8XDS4
uniprot id: A0A6Q2XKU9
names: Similarity
messages: Belongs to the peptidase M14 family.

8010:LOC105015627
gene id: 8010:LOC105015627
uniprot id: A0A3P8ZFE9
names: Subcellular Location Annotation
messages: Nucleus

8010:slc30a2
gene id: 8010:slc30a2
uniprot id: A0A3P9AP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8010:mns1
gene id: 8010:mns1
uniprot id: A0A3P8Y7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

8010:pld7
gene id: 8010:pld7
uniprot id: A0A3P8XFY2
uniprot id: A0A3P8ZEG2
uniprot id: A0A6Q2WYT8
names: Similarity
messages: Belongs to the phospholipase D family.

8010:LOC105021846
gene id: 8010:LOC105021846
uniprot id: A0A3P8XU97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105027864
gene id: 8010:LOC105027864
uniprot id: A0A3P8XIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cell membrane
messages: Membrane
messages: secretory vesicle membrane

8010:wnt5a
gene id: 8010:wnt5a
uniprot id: A0A3P8ZVF1
uniprot id: A0A6Q2YEY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:ntf3
gene id: 8010:ntf3
uniprot id: A0A3P8ZVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

8010:bbs10
gene id: 8010:bbs10
uniprot id: A0A3P8YML7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8010:LOC105018694
gene id: 8010:LOC105018694
uniprot id: A0A3P9ABZ4
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8010:tmem97
gene id: 8010:tmem97
uniprot id: A0A3P8YZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8010:zgc:172121
gene id: 8010:zgc:172121
uniprot id: A0A3P8XW38
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8010:onecut3b
gene id: 8010:onecut3b
uniprot id: A0A3P8ZRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8010:kcnj10a
gene id: 8010:kcnj10a
uniprot id: A0A3P8ZJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:LOC105023747
gene id: 8010:LOC105023747
uniprot id: A0A3P8Z5D0
names: Similarity
messages: Belongs to the intermediate filament family.

8010:LOC105013732
gene id: 8010:LOC105013732
uniprot id: A0A3P8YWN4
names: Similarity
messages: Belongs to the TAFA family.

8010:dcbld2
gene id: 8010:dcbld2
uniprot id: A0A3P8YVH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:grm8a
gene id: 8010:grm8a
uniprot id: A0A3P9AAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8010:ranbp9
gene id: 8010:ranbp9
uniprot id: A0A3P9A9R9
names: Similarity
messages: Belongs to the RANBP9/10 family.

8010:ndufv2
gene id: 8010:ndufv2
uniprot id: A0A6Q2YNL7
uniprot id: A0A6Q2Z588
uniprot id: C1BXQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

8010:picalma
gene id: 8010:picalma
uniprot id: A0A3P8YZ33
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8010:pdpk1b
gene id: 8010:pdpk1b
uniprot id: A0A3P8XYP0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

8010:dgke
gene id: 8010:dgke
uniprot id: A0A3P8Y9M1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8010:htr7c
gene id: 8010:htr7c
uniprot id: A0A3P8XTU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105024958
gene id: 8010:LOC105024958
uniprot id: A0A3P8YQC6
uniprot id: A0A3P8YRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

8010:ap1g1
gene id: 8010:ap1g1
uniprot id: A0A3P9A2Y7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8010:gtf2f1
gene id: 8010:gtf2f1
uniprot id: A0A3P8ZGM6
uniprot id: A0A6Q2YTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

8010:reep5
gene id: 8010:reep5
uniprot id: C1BXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8010:nr5a5
gene id: 8010:nr5a5
uniprot id: A0A3P8ZYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8010:dhx58
gene id: 8010:dhx58
uniprot id: A0A3P8YSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8010:LOC105006089
gene id: 8010:LOC105006089
uniprot id: A0A3P8YRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:rx1
gene id: 8010:rx1
uniprot id: A0A6Q2YAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8010:ppp1r12c
gene id: 8010:ppp1r12c
uniprot id: A0A6Q2XXL3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8010:pgam2
gene id: 8010:pgam2
uniprot id: A0A3P8ZY31
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8010:rps24
gene id: 8010:rps24
uniprot id: A0A3P8ZA53
uniprot id: C1BY48
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

8010:polrmt
gene id: 8010:polrmt
uniprot id: A0A3P8YU46
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8010:gem
gene id: 8010:gem
uniprot id: A0A3P8XXU8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8010:dpysl4
gene id: 8010:dpysl4
uniprot id: A0A3P8YC28
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8010:pou2f3
gene id: 8010:pou2f3
uniprot id: A0A3P9ACG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

8010:rasgrp2
gene id: 8010:rasgrp2
uniprot id: A0A3P9ALC6
names: Similarity
messages: Belongs to the RASGRP family.

8010:LOC105022679
gene id: 8010:LOC105022679
uniprot id: A0A3P8ZGF8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:LOC105008992
gene id: 8010:LOC105008992
uniprot id: A0A6Q2XW06
uniprot id: W5VP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8010:p2rx4a
gene id: 8010:p2rx4a
uniprot id: A0A3P9AHM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8010:mrpl24
gene id: 8010:mrpl24
uniprot id: A0A3P8YHM2
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8010:ugp2b
gene id: 8010:ugp2b
uniprot id: A0A3P8YCX5
uniprot id: A0A6Q2WWA5
uniprot id: A0A6Q2YWA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8010:LOC105022083
gene id: 8010:LOC105022083
uniprot id: A0A3P8YWF6
names: Similarity
messages: Belongs to the OSBP family.

8010:bpnt1
gene id: 8010:bpnt1
uniprot id: A0A3P8XWB9
uniprot id: A0A3P8ZTV1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8010:itih6
gene id: 8010:itih6
uniprot id: A0A3P8ZLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8010:LOC105012867
gene id: 8010:LOC105012867
uniprot id: A0A3P8YET9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8010:fgb
gene id: 8010:fgb
uniprot id: A0A3P8XRG0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8010:wscd2
gene id: 8010:wscd2
uniprot id: A0A3P8YAT0
names: Similarity
messages: Belongs to the WSCD family.

8010:LOC105027728
gene id: 8010:LOC105027728
uniprot id: A0A3P8YIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:atp2a1
gene id: 8010:atp2a1
uniprot id: A0A3P8Z9A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8010:zgc:171929
gene id: 8010:zgc:171929
uniprot id: A0A6Q2XGY6
names: Subcellular Location Annotation
messages: Nucleus

8010:frzb
gene id: 8010:frzb
uniprot id: A0A3P8XXY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

8010:mak16
gene id: 8010:mak16
uniprot id: C1BW57
names: Similarity
messages: Belongs to the MAK16 family.

8010:spty2d1
gene id: 8010:spty2d1
uniprot id: A0A3P9AKE4
names: Similarity
messages: Belongs to the SPT2 family.

8010:hs6st1a
gene id: 8010:hs6st1a
uniprot id: A0A3P8Z7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8010:xkr9
gene id: 8010:xkr9
uniprot id: A0A3P8XRJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:LOC105008196
gene id: 8010:LOC105008196
uniprot id: A0A3P8ZNH2
names: Subcellular Location Annotation
messages: Membrane

8010:plg
gene id: 8010:plg
uniprot id: A0A3P8Z4D8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

8010:sostdc1a
gene id: 8010:sostdc1a
uniprot id: A0A3P8YGI0
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105011288
gene id: 8010:LOC105011288
uniprot id: A0A3P8Z2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8010:eef1g
gene id: 8010:eef1g
uniprot id: A0A3P8XBP3
uniprot id: A0A3P8ZEZ6
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

8010:LOC105025658
gene id: 8010:LOC105025658
uniprot id: A0A3P8YL81
uniprot id: A0A3P8YNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8010:pex14
gene id: 8010:pex14
uniprot id: A0A3P8YAB5
uniprot id: A0A3P9A055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

8010:zgc:101765
gene id: 8010:zgc:101765
uniprot id: A0A3P8ZYM2
uniprot id: A0A3P8ZYW3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8010:LOC105019694
gene id: 8010:LOC105019694
uniprot id: A0A3P8ZA29
names: Subcellular Location Annotation
messages: Membrane

8010:kcnq2a
gene id: 8010:kcnq2a
uniprot id: A0A3P8XCW3
uniprot id: A0A3P8XCX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:cpeb1b
gene id: 8010:cpeb1b
uniprot id: A0A3P8Z2C0
uniprot id: A0A3P9AKD5
uniprot id: A0A6Q2YXY4
names: Similarity
messages: Belongs to the RRM CPEB family.

8010:shoc2
gene id: 8010:shoc2
uniprot id: A0A3P8Z669
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

8010:abr
gene id: 8010:abr
uniprot id: A0A3P9ALJ7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8010:zeb2a
gene id: 8010:zeb2a
uniprot id: A0A3P8ZIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

8010:trmt61a
gene id: 8010:trmt61a
uniprot id: A0A3P8ZZ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

8010:LOC105008676
gene id: 8010:LOC105008676
uniprot id: A0A3P8Y4C2
names: Similarity
messages: Belongs to the intermediate filament family.

8010:vgll3
gene id: 8010:vgll3
uniprot id: A0A3P8XSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8010:cdc34a
gene id: 8010:cdc34a
uniprot id: A0A3P8YJU5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:pgls
gene id: 8010:pgls
uniprot id: C1BWG3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

8010:mmp19
gene id: 8010:mmp19
uniprot id: A0A3P8YYR4
uniprot id: A0A6Q2Y857
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:LOC105015026
gene id: 8010:LOC105015026
uniprot id: A0A3P8Y8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8010:LOC105020672
gene id: 8010:LOC105020672
uniprot id: A0A6Q2ZFY5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

8010:LOC105011964
gene id: 8010:LOC105011964
uniprot id: A0A3P9AP62
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:mcee
gene id: 8010:mcee
uniprot id: C1BWH4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

8010:star2
gene id: 8010:star2
uniprot id: A0A3P9A1S1
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

8010:bmpr1ba
gene id: 8010:bmpr1ba
uniprot id: A0A3P8YY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:tmem106ba
gene id: 8010:tmem106ba
uniprot id: A0A3P8YEQ3
names: Similarity
messages: Belongs to the TMEM106 family.

8010:LOC105020320
gene id: 8010:LOC105020320
uniprot id: A0A3P8XPC3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8010:LOC105009249
gene id: 8010:LOC105009249
uniprot id: A0A3P8XV05
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8010:rpl17
gene id: 8010:rpl17
uniprot id: C1BY54
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8010:tapt1a
gene id: 8010:tapt1a
uniprot id: A0A3P8ZE42
uniprot id: A0A3P8ZF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

8010:sirt2
gene id: 8010:sirt2
uniprot id: A0A3P9AEL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8010:ndel1a
gene id: 8010:ndel1a
uniprot id: A0A3P8XW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8010:gab3
gene id: 8010:gab3
uniprot id: A0A3P8Y057
names: Similarity
messages: Belongs to the GAB family.

8010:LOC105021467
gene id: 8010:LOC105021467
uniprot id: A0A3P8XYJ5
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8010:LOC105030111
gene id: 8010:LOC105030111
uniprot id: A0A3P8ZBQ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

8010:st6galnac4
gene id: 8010:st6galnac4
uniprot id: A0A3P8Z6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:spi1a
gene id: 8010:spi1a
uniprot id: A0A3P8Z0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:wdr12
gene id: 8010:wdr12
uniprot id: A0A6Q2XGE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8010:gngt1
gene id: 8010:gngt1
uniprot id: A0A3P8YY51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:prepl
gene id: 8010:prepl
uniprot id: A0A3P8ZZA0
names: Similarity
messages: Belongs to the peptidase S9A family.

8010:slc6a11a
gene id: 8010:slc6a11a
uniprot id: A0A3P8XCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:LOC105025937
gene id: 8010:LOC105025937
uniprot id: A0A3P9ADX8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:LOC105023655
gene id: 8010:LOC105023655
uniprot id: A0A3P8ZJB8
names: Subcellular Location Annotation
messages: Nucleus

8010:irx1b
gene id: 8010:irx1b
uniprot id: A0A3P8Z9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8010:LOC105016389
gene id: 8010:LOC105016389
uniprot id: A0A3P8XST5
uniprot id: A0A3P8ZNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8010:LOC105012345
gene id: 8010:LOC105012345
uniprot id: A0A3P9ACK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:LOC105020202
gene id: 8010:LOC105020202
uniprot id: A0A3P8XIA5
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8010:LOC105006094
gene id: 8010:LOC105006094
uniprot id: C1BZM9
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8010:mthfd1b
gene id: 8010:mthfd1b
uniprot id: A0A3P8XDL1
uniprot id: A0A3P8ZG15
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

8010:pts
gene id: 8010:pts
uniprot id: A0A3P8Z1T2
uniprot id: C1BYP4
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

8010:ednraa
gene id: 8010:ednraa
uniprot id: A0A3P8YC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

8010:adamts12
gene id: 8010:adamts12
uniprot id: A0A3P8ZG93
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:hpse2
gene id: 8010:hpse2
uniprot id: A0A3P8Z250
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

8010:sypb
gene id: 8010:sypb
uniprot id: A0A3P9AK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane
messages: synaptosome

8010:snx14
gene id: 8010:snx14
uniprot id: A0A3P9A8F5
names: Similarity
messages: Belongs to the sorting nexin family.

8010:LOC105006869
gene id: 8010:LOC105006869
uniprot id: A0A3P8Y6Y9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:slc6a4b
gene id: 8010:slc6a4b
uniprot id: A0A3P8XA08
uniprot id: A0A6Q2XWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:LOC105028956
gene id: 8010:LOC105028956
uniprot id: A0A3P8YA89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8010:saxo2
gene id: 8010:saxo2
uniprot id: A0A3P8XBN0
names: Similarity
messages: Belongs to the FAM154 family.

8010:LOC105014088
gene id: 8010:LOC105014088
uniprot id: A0A3P8XB55
uniprot id: A0A6Q2XUD9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8010:cpxm2
gene id: 8010:cpxm2
uniprot id: A0A3P9A648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8010:fgf5
gene id: 8010:fgf5
uniprot id: A0A3P8YBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

8010:pgm5
gene id: 8010:pgm5
uniprot id: A0A3P8X8D5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8010:tlx2
gene id: 8010:tlx2
uniprot id: A0A6Q2WQC8
names: Subcellular Location Annotation
messages: Nucleus

8010:tgfb2
gene id: 8010:tgfb2
uniprot id: A0A6Q2YKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8010:pitrm1
gene id: 8010:pitrm1
uniprot id: A0A3P8XU63
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

8010:si:dkeyp-67a8.2
gene id: 8010:si:dkeyp-67a8.2
uniprot id: A0A3P8XLN7
names: Subcellular Location Annotation
messages: Membrane

8010:src
gene id: 8010:src
uniprot id: A0A3P8XJT5
uniprot id: A0A3P8XJX0
uniprot id: A0A3P8ZK92
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:LOC105018538
gene id: 8010:LOC105018538
uniprot id: A0A3P8Y5C1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:tlcd5a
gene id: 8010:tlcd5a
uniprot id: A0A3P8YFP6
names: Subcellular Location Annotation
messages: Membrane

8010:si:rp71-45k5.2
gene id: 8010:si:rp71-45k5.2
uniprot id: A0A3P8Z322
names: Subcellular Location Annotation
messages: Nucleus

8010:golph3
gene id: 8010:golph3
uniprot id: A0A3P8Z6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8010:zgc:86896
gene id: 8010:zgc:86896
uniprot id: A0A3P8Y1E1
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

8010:csnk2a2b
gene id: 8010:csnk2a2b
uniprot id: A0A3P8Y1N4
uniprot id: A0A3P8ZVN2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:ankhb
gene id: 8010:ankhb
uniprot id: A0A3P8YRL1
uniprot id: A0A6Q2ZFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8010:skap2
gene id: 8010:skap2
uniprot id: A0A3P8XRB1
names: Similarity
messages: Belongs to the SKAP family.

8010:soul5l
gene id: 8010:soul5l
uniprot id: A0A3P8Y596
names: Similarity
messages: Belongs to the HEBP family.

8010:LOC105016993
gene id: 8010:LOC105016993
uniprot id: A0A3P8YW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:ube2nb
gene id: 8010:ube2nb
uniprot id: C1BZ58
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:si:dkey-183i3.9
gene id: 8010:si:dkey-183i3.9
uniprot id: A0A3P8YEY6
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105012548
gene id: 8010:LOC105012548
uniprot id: A0A3P8XVQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8010:alg9
gene id: 8010:alg9
uniprot id: A0A3P8Y527
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:ncl
gene id: 8010:ncl
uniprot id: A0A3P8XMP4
names: Subcellular Location Annotation
messages: nucleolus

8010:slc37a2
gene id: 8010:slc37a2
uniprot id: A0A3P8YTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8010:mif
gene id: 8010:mif
uniprot id: C1BZJ5
names: Similarity
messages: Belongs to the MIF family.

8010:kcnj1b
gene id: 8010:kcnj1b
uniprot id: A0A3P8YW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:capn3b
gene id: 8010:capn3b
uniprot id: A0A3P8YCQ4
uniprot id: A0A3P8YCY3
uniprot id: A0A3P9A3W7
uniprot id: A0A6Q2YFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

8010:calhm2.1
gene id: 8010:calhm2.1
uniprot id: A0A3P8YED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8010:thyn1
gene id: 8010:thyn1
uniprot id: A0A3P9AGY8
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8010:wnt9b
gene id: 8010:wnt9b
uniprot id: A0A3P8YVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:myoz1b
gene id: 8010:myoz1b
uniprot id: A0A3P8X8W4
names: Similarity
messages: Belongs to the myozenin family.

8010:f9a
gene id: 8010:f9a
uniprot id: A0A3P8ZF06
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105022181
gene id: 8010:LOC105022181
uniprot id: A0A3P8Z682
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8010:ptger3
gene id: 8010:ptger3
uniprot id: A0A3P8Y855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:tnr
gene id: 8010:tnr
uniprot id: A0A3P8ZWD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:derl1
gene id: 8010:derl1
uniprot id: A0A3P8Z747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

8010:cpsf3
gene id: 8010:cpsf3
uniprot id: A0A3P9A1V1
names: Subcellular Location Annotation
messages: Nucleus

8010:slc44a4
gene id: 8010:slc44a4
uniprot id: A0A3P8ZJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8010:epb41l5
gene id: 8010:epb41l5
uniprot id: A0A3P8XHH0
uniprot id: A0A3P8XLK4
uniprot id: A0A3P8ZIB7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

8010:actn4
gene id: 8010:actn4
uniprot id: A0A3P8YPP6
uniprot id: A0A3P9A9T7
names: Similarity
messages: Belongs to the alpha-actinin family.

8010:nbn
gene id: 8010:nbn
uniprot id: A0A3P8Y3I3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

8010:ppp1cab
gene id: 8010:ppp1cab
uniprot id: A0A3P9AM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm

8010:atxn2l
gene id: 8010:atxn2l
uniprot id: A0A3P8Z9W1
uniprot id: A0A3P9AN65
names: Similarity
messages: Belongs to the ataxin-2 family.

8010:fa2h
gene id: 8010:fa2h
uniprot id: A0A3P8Y1X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:anp32e
gene id: 8010:anp32e
uniprot id: A0A3P8YL88
names: Similarity
messages: Belongs to the ANP32 family.

8010:cnnm2b
gene id: 8010:cnnm2b
uniprot id: A0A3P8XEJ7
uniprot id: A0A3P8XEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8010:si:ch211-283g2.1
gene id: 8010:si:ch211-283g2.1
uniprot id: A0A3P8Z253
uniprot id: A0A6Q2Z411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:si:dkeyp-120h9.1
gene id: 8010:si:dkeyp-120h9.1
uniprot id: A0A3P8XI31
names: Subcellular Location Annotation
messages: Membrane

8010:memo1
gene id: 8010:memo1
uniprot id: A0A3P9A9X7
names: Similarity
messages: Belongs to the MEMO1 family.

8010:capn10
gene id: 8010:capn10
uniprot id: A0A3P8ZWP1
names: Similarity
messages: Belongs to the peptidase C2 family.

8010:pelo
gene id: 8010:pelo
uniprot id: A0A3P9AM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

8010:LOC105014911
gene id: 8010:LOC105014911
uniprot id: A0A3P9AI91
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8010:tm6sf2
gene id: 8010:tm6sf2
uniprot id: A0A3P8YWW2
names: Subcellular Location Annotation
messages: Membrane

8010:nup62l
gene id: 8010:nup62l
uniprot id: A0A3P8XX77
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

8010:sstr1a
gene id: 8010:sstr1a
uniprot id: A0A3P8XB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:skib
gene id: 8010:skib
uniprot id: A0A3P8Z7B1
names: Similarity
messages: Belongs to the SKI family.

8010:LOC105017213
gene id: 8010:LOC105017213
uniprot id: A0A3P8YJ20
uniprot id: A0A3P9A7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:LOC105011674
gene id: 8010:LOC105011674
uniprot id: A0A3P8Y4Y2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:LOC105010631
gene id: 8010:LOC105010631
uniprot id: A0A3P8Y263
uniprot id: A0A3P8Y289
uniprot id: A0A3P8Y3R2
uniprot id: A0A3P8ZX36
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

8010:LOC105022889
gene id: 8010:LOC105022889
uniprot id: A0A3P8YWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

8010:LOC105031498
gene id: 8010:LOC105031498
uniprot id: A0A3P8YIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

8010:coro1cb
gene id: 8010:coro1cb
uniprot id: A0A3P8Z010
uniprot id: A0A3P8Z1Q7
names: Similarity
messages: Belongs to the WD repeat coronin family.

8010:romo1
gene id: 8010:romo1
uniprot id: C1BYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

8010:adgrg3
gene id: 8010:adgrg3
uniprot id: A0A3P8YXP2
names: Subcellular Location Annotation
messages: Membrane

8010:chrna10a
gene id: 8010:chrna10a
uniprot id: A0A3P9A0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:kdm7aa
gene id: 8010:kdm7aa
uniprot id: A0A3P8ZD69
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8010:LOC105028312
gene id: 8010:LOC105028312
uniprot id: A0A6Q2Z507
names: Similarity
messages: Belongs to the TGF-beta family.

8010:LOC105023146
gene id: 8010:LOC105023146
uniprot id: A0A3P8X8P1
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8010:snx11
gene id: 8010:snx11
uniprot id: A0A3P8ZQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8010:gadd45aa
gene id: 8010:gadd45aa
uniprot id: A0A3P9ADN0
names: Similarity
messages: Belongs to the GADD45 family.

8010:LOC105007889
gene id: 8010:LOC105007889
uniprot id: A0A3P8XPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

8010:actr1
gene id: 8010:actr1
uniprot id: A0A3P8XP01
names: Similarity
messages: Belongs to the actin family.

8010:tubgcp4
gene id: 8010:tubgcp4
uniprot id: A0A3P8XA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8010:ccm2
gene id: 8010:ccm2
uniprot id: A0A3P8XJB5
uniprot id: A0A3P8XJF2
uniprot id: A0A6Q2WX77
names: Similarity
messages: Belongs to the CCM2 family.

8010:c1qbp
gene id: 8010:c1qbp
uniprot id: A0A3P9AFQ9
uniprot id: C1BWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

8010:inip
gene id: 8010:inip
uniprot id: A0A3P8YAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

8010:sept5b
gene id: 8010:sept5b
uniprot id: A0A3P8XL40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

8010:tmem167b
gene id: 8010:tmem167b
uniprot id: A0A3P9AEB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:mrpl47
gene id: 8010:mrpl47
uniprot id: C1BW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

8010:slc24a2
gene id: 8010:slc24a2
uniprot id: A0A3P8YX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:LOC105030247
gene id: 8010:LOC105030247
uniprot id: A0A3P8Z879
uniprot id: C1BXQ5
names: Similarity
messages: Belongs to the TACO1 family.

8010:cenpk
gene id: 8010:cenpk
uniprot id: A0A3P8XFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

8010:oclna
gene id: 8010:oclna
uniprot id: A0A3P8ZQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:meis1a
gene id: 8010:meis1a
uniprot id: A0A3P8ZXS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:efhb
gene id: 8010:efhb
uniprot id: A0A3P9A2E7
names: Subcellular Location Annotation
messages: cilium axoneme

8010:napsa
gene id: 8010:napsa
uniprot id: A0A3P8Y344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8010:LOC105005921
gene id: 8010:LOC105005921
uniprot id: A0A3P8YS37
names: Similarity
messages: Belongs to the CRK family.

8010:ppil6
gene id: 8010:ppil6
uniprot id: A0A3P8YMY6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:nbl1
gene id: 8010:nbl1
uniprot id: A0A3P8YB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8010:LOC105027310
gene id: 8010:LOC105027310
uniprot id: A0A3P9A9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8010:LOC105017064
gene id: 8010:LOC105017064
uniprot id: A0A6Q2WTY6
names: Similarity
messages: Belongs to the FAM219 family.

8010:lonp1
gene id: 8010:lonp1
uniprot id: A0A3P8ZVR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

8010:tbx2a
gene id: 8010:tbx2a
uniprot id: A0A3P8Y6G2
uniprot id: A0A6Q2WZG7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105019098
gene id: 8010:LOC105019098
uniprot id: C1BXU1
names: Subcellular Location Annotation
messages: Nucleus

8010:arap3
gene id: 8010:arap3
uniprot id: A0A3P8Z3R1
names: Subcellular Location Annotation
messages: Cytoplasm

8010:polr1a
gene id: 8010:polr1a
uniprot id: A0A3P9A0A2
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8010:mrpl9
gene id: 8010:mrpl9
uniprot id: A0A3P9A3L1
uniprot id: C1BZ77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

8010:hoxb3a
gene id: 8010:hoxb3a
uniprot id: A0A3P9A3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8010:wt1a
gene id: 8010:wt1a
uniprot id: A0A3P8YJH9
uniprot id: A0A3P9A734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

8010:sdc4
gene id: 8010:sdc4
uniprot id: A0A6Q2XW58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8010:eif3k
gene id: 8010:eif3k
uniprot id: A0A3P8YPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8010:elapor2
gene id: 8010:elapor2
uniprot id: A0A3P8XAV3
uniprot id: A0A3P8ZFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8010:ankle2
gene id: 8010:ankle2
uniprot id: A0A3P8ZMZ3
names: Similarity
messages: Belongs to the ANKLE2 family.

8010:LOC105007434
gene id: 8010:LOC105007434
uniprot id: A0A3P8Y0H0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:snrpd1
gene id: 8010:snrpd1
uniprot id: A0A6Q2XQU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8010:slc16a4
gene id: 8010:slc16a4
uniprot id: A0A3P8YK04
names: Subcellular Location Annotation
messages: Membrane

8010:ccdc58
gene id: 8010:ccdc58
uniprot id: C1BYE5
names: Similarity
messages: Belongs to the MIX23 family.

8010:kcnh3
gene id: 8010:kcnh3
uniprot id: A0A3P8ZJE8
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8010:wdr32
gene id: 8010:wdr32
uniprot id: A0A3P8Z857
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8010:apoeb
gene id: 8010:apoeb
uniprot id: A0A6Q2ZLF6
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8010:LOC105030945
gene id: 8010:LOC105030945
uniprot id: A0A3P8YSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:anxa3b
gene id: 8010:anxa3b
uniprot id: C1BWX6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8010:dnaaf6
gene id: 8010:dnaaf6
uniprot id: A0A3P8ZY88
names: Similarity
messages: Belongs to the PIH1 family.

8010:gpn1
gene id: 8010:gpn1
uniprot id: A0A3P8ZKM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

8010:LOC105028427
gene id: 8010:LOC105028427
uniprot id: A0A3P8Z5P0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

8010:zw10
gene id: 8010:zw10
uniprot id: A0A3P8YF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

8010:pmm2
gene id: 8010:pmm2
uniprot id: A0A3P8ZK24
uniprot id: C1BX48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8010:eif3g
gene id: 8010:eif3g
uniprot id: A0A3P9AN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

8010:nol6
gene id: 8010:nol6
uniprot id: A0A3P8YQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

8010:immp2l
gene id: 8010:immp2l
uniprot id: A0A3P8YLS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

8010:ccr7
gene id: 8010:ccr7
uniprot id: A0A3P8ZTK2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:slc1a4
gene id: 8010:slc1a4
uniprot id: A0A3P9A1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:nudt18
gene id: 8010:nudt18
uniprot id: A0A3P8ZSH1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8010:fam171a1
gene id: 8010:fam171a1
uniprot id: A0A3P8ZU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8010:prdm13
gene id: 8010:prdm13
uniprot id: A0A3P8Z1B0
names: Subcellular Location Annotation
messages: Nucleus

8010:sult5a1
gene id: 8010:sult5a1
uniprot id: A0A3P8YR09
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:nrxn2a
gene id: 8010:nrxn2a
uniprot id: A0A3P9ALD9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:acp5b
gene id: 8010:acp5b
uniprot id: C1BYH9
names: Cofactor
messages: Binds 2 iron ions per subunit.

8010:sgf29
gene id: 8010:sgf29
uniprot id: A0A3P9API2
names: Subcellular Location Annotation
messages: Nucleus

8010:fntb
gene id: 8010:fntb
uniprot id: A0A3P8YWB3
uniprot id: A0A6Q2XR35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

8010:LOC105014523
gene id: 8010:LOC105014523
uniprot id: A0A3P9AQ62
names: Subcellular Location Annotation
messages: Secreted

8010:bnip3lb
gene id: 8010:bnip3lb
uniprot id: A0A3P8YQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8010:sart3
gene id: 8010:sart3
uniprot id: A0A3P9A113
names: Subcellular Location Annotation
messages: nucleoplasm

8010:ntsr1
gene id: 8010:ntsr1
uniprot id: A0A3P8ZU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:grb2a
gene id: 8010:grb2a
uniprot id: A0A3P8ZLJ2
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

8010:pex7
gene id: 8010:pex7
uniprot id: A0A3P9AG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

8010:polr2l
gene id: 8010:polr2l
uniprot id: C1BZA7
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

8010:LOC105015051
gene id: 8010:LOC105015051
uniprot id: A0A3P8ZFM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:hao1
gene id: 8010:hao1
uniprot id: A0A3P8Y8Y2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8010:rpl23a
gene id: 8010:rpl23a
uniprot id: A0A3P9ABA6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8010:tgfb1a
gene id: 8010:tgfb1a
uniprot id: A0A3P8Z0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

8010:me3
gene id: 8010:me3
uniprot id: A0A3P8YZR6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8010:hoxa9b
gene id: 8010:hoxa9b
uniprot id: A0A3P8XR51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:nr1h4
gene id: 8010:nr1h4
uniprot id: A0A3P8ZA96
uniprot id: A0A3P9AQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:faim2a
gene id: 8010:faim2a
uniprot id: A0A6Q2X5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8010:rps3
gene id: 8010:rps3
uniprot id: A0A3P8ZA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: nucleolus
messages: spindle

8010:pus1
gene id: 8010:pus1
uniprot id: A0A3P8ZUC9
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8010:dram2b
gene id: 8010:dram2b
uniprot id: A0A3P8XHP8
names: Subcellular Location Annotation
messages: Membrane

8010:ptdss1a
gene id: 8010:ptdss1a
uniprot id: A0A3P8ZF24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:si:ch211-191a24.3
gene id: 8010:si:ch211-191a24.3
uniprot id: A0A3P8X7J1
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8010:tp53rk
gene id: 8010:tp53rk
uniprot id: A0A3P9A1Q9
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

8010:nr0b1
gene id: 8010:nr0b1
uniprot id: A0A3P9AFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8010:ren
gene id: 8010:ren
uniprot id: A0A3P9AQN3
names: Similarity
messages: Belongs to the peptidase A1 family.

8010:LOC105017783
gene id: 8010:LOC105017783
uniprot id: A0A3P8XR74
names: Subcellular Location Annotation
messages: Nucleus

8010:elf2a
gene id: 8010:elf2a
uniprot id: A0A3P8X917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:lypd6
gene id: 8010:lypd6
uniprot id: A0A6Q2WT03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:sfrp1a
gene id: 8010:sfrp1a
uniprot id: A0A3P8XH15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:wnt11
gene id: 8010:wnt11
uniprot id: A0A3P8ZA62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:cbr1
gene id: 8010:cbr1
uniprot id: A0A3P8YYB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:atpv0e2
gene id: 8010:atpv0e2
uniprot id: A0A3P8Z237
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8010:LOC105024413
gene id: 8010:LOC105024413
uniprot id: A0A3P8XLJ6
names: Subcellular Location Annotation
messages: Nucleus

8010:gpm6aa
gene id: 8010:gpm6aa
uniprot id: A0A3P9AIE7
uniprot id: A0A6Q2ZKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8010:LOC105006230
gene id: 8010:LOC105006230
uniprot id: A0A3P8XV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:cxcl12a
gene id: 8010:cxcl12a
uniprot id: A0A3P8XZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8010:sema4c
gene id: 8010:sema4c
uniprot id: A0A3P8XLK6
uniprot id: A0A3P8XQ81
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:maea
gene id: 8010:maea
uniprot id: A0A3P8YAA9
names: Subcellular Location Annotation
messages: Nucleus matrix

8010:cxcl19
gene id: 8010:cxcl19
uniprot id: A0A6Q2ZD41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8010:ints9
gene id: 8010:ints9
uniprot id: A0A3P8XZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

8010:rpl27
gene id: 8010:rpl27
uniprot id: A0A3P8YTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

8010:LOC105017345
gene id: 8010:LOC105017345
uniprot id: A0A3P8XI10
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8010:fgfbp2b
gene id: 8010:fgfbp2b
uniprot id: A0A3P8ZKE9
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8010:LOC105027652
gene id: 8010:LOC105027652
uniprot id: A0A6Q2YF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8010:ddx31
gene id: 8010:ddx31
uniprot id: A0A3P8XX93
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:LOC105013579
gene id: 8010:LOC105013579
uniprot id: A0A3P9AHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8010:ddx3xb
gene id: 8010:ddx3xb
uniprot id: A0A3P8XFH1
uniprot id: A0A3P8XJF1
uniprot id: A0A3P8XJI8
uniprot id: A0A3P8ZI29
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:mapk3
gene id: 8010:mapk3
uniprot id: A0A3P9AMH2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8010:slc29a1b
gene id: 8010:slc29a1b
uniprot id: A0A3P8Z8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8010:gabrr3a
gene id: 8010:gabrr3a
uniprot id: A0A3P8YXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:LOC105016659
gene id: 8010:LOC105016659
uniprot id: A0A3P8YM19
uniprot id: A0A6Q2XY44
names: Subcellular Location Annotation
messages: Nucleus

8010:arrdc3b
gene id: 8010:arrdc3b
uniprot id: A0A3P8XHP1
names: Similarity
messages: Belongs to the arrestin family.

8010:slc12a9
gene id: 8010:slc12a9
uniprot id: A0A3P8XPT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

8010:cep170ab
gene id: 8010:cep170ab
uniprot id: A0A3P8ZEN4
names: Similarity
messages: Belongs to the CEP170 family.

8010:wnt4b
gene id: 8010:wnt4b
uniprot id: A0A3P8YPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:nr2f6a
gene id: 8010:nr2f6a
uniprot id: A0A3P8YXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:trnt1
gene id: 8010:trnt1
uniprot id: A0A3P8XFR7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

8010:mnx2b
gene id: 8010:mnx2b
uniprot id: A0A6Q2XWH3
names: Subcellular Location Annotation
messages: Nucleus

8010:klc3
gene id: 8010:klc3
uniprot id: A0A3P9AAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8010:nrf1
gene id: 8010:nrf1
uniprot id: A0A3P8Z6R7
uniprot id: A0A3P8Z8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

8010:map6b
gene id: 8010:map6b
uniprot id: A0A3P8YUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8010:stag2a
gene id: 8010:stag2a
uniprot id: A0A6Q2YQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8010:gpr158b
gene id: 8010:gpr158b
uniprot id: A0A3P8YJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8010:LOC105021832
gene id: 8010:LOC105021832
uniprot id: A0A3P8XW75
names: Subcellular Location Annotation
messages: Membrane

8010:crb2a
gene id: 8010:crb2a
uniprot id: A0A3P9AFF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cfap43
gene id: 8010:cfap43
uniprot id: A0A3P8XTF8
names: Similarity
messages: Belongs to the CFAP43 family.

8010:slc25a11
gene id: 8010:slc25a11
uniprot id: A0A3P8Z0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:LOC105009742
gene id: 8010:LOC105009742
uniprot id: A0A3P8XVV2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:pex5lb
gene id: 8010:pex5lb
uniprot id: A0A3P9A8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane

8010:cd74b
gene id: 8010:cd74b
uniprot id: A0A3P8XGE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:alox5ap
gene id: 8010:alox5ap
uniprot id: A0A3P8XRF0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8010:gng2
gene id: 8010:gng2
uniprot id: A0A6Q2YL74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:dazap2
gene id: 8010:dazap2
uniprot id: A0A3P8XC64
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

8010:hadhb
gene id: 8010:hadhb
uniprot id: A0A3P8XT04
uniprot id: A0A3P8XV64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8010:ppp3cca
gene id: 8010:ppp3cca
uniprot id: A0A3P8XHH1
uniprot id: A0A3P8ZIK6
uniprot id: A0A6Q2X2J4
uniprot id: A0A6Q2XJS8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8010:ano5a
gene id: 8010:ano5a
uniprot id: A0A3P8Z1T3
uniprot id: A0A3P9AHR5
uniprot id: A0A3P9AIN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105010884
gene id: 8010:LOC105010884
uniprot id: A0A3P8Z3W9
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8010:mtmr2
gene id: 8010:mtmr2
uniprot id: A0A3P8XU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8010:LOC105007967
gene id: 8010:LOC105007967
uniprot id: C1BZU3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8010:rab3c
gene id: 8010:rab3c
uniprot id: A0A3P8ZV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8010:LOC105021320
gene id: 8010:LOC105021320
uniprot id: A0A3P8XH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:wscd1b
gene id: 8010:wscd1b
uniprot id: A0A3P8ZBL3
names: Similarity
messages: Belongs to the WSCD family.

8010:xkr6b
gene id: 8010:xkr6b
uniprot id: A0A3P8ZKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:LOC105021703
gene id: 8010:LOC105021703
uniprot id: A0A3P8YJL3
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8010:LOC105007231
gene id: 8010:LOC105007231
uniprot id: A0A3P8XJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8010:mrps2
gene id: 8010:mrps2
uniprot id: A0A3P8XAY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

8010:folr
gene id: 8010:folr
uniprot id: A0A3P8ZWH6
names: Similarity
messages: Belongs to the folate receptor family.

8010:rb1
gene id: 8010:rb1
uniprot id: A0A3P8ZMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8010:LOC105024459
gene id: 8010:LOC105024459
uniprot id: A0A3P8YZK6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:tmem163a
gene id: 8010:tmem163a
uniprot id: A0A3P8XGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

8010:LOC109614647
gene id: 8010:LOC109614647
uniprot id: A0A3P9A0W6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:fas
gene id: 8010:fas
uniprot id: A0A3P9AFT5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

8010:nfascb
gene id: 8010:nfascb
uniprot id: A0A3P8YWX6
uniprot id: A0A3P9AGK7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8010:alx1
gene id: 8010:alx1
uniprot id: A0A3P8ZWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8010:antkmt
gene id: 8010:antkmt
uniprot id: A0A3P8ZT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8010:ilkap
gene id: 8010:ilkap
uniprot id: A0A3P8XJN8
names: Similarity
messages: Belongs to the PP2C family.

8010:inpp5l
gene id: 8010:inpp5l
uniprot id: A0A3P8YLA1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8010:loxl5a
gene id: 8010:loxl5a
uniprot id: A0A3P9ANS0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8010:vamp5
gene id: 8010:vamp5
uniprot id: A0A6Q2YAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8010:LOC105010674
gene id: 8010:LOC105010674
uniprot id: A0A3P8ZSE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:si:dkey-247m21.3
gene id: 8010:si:dkey-247m21.3
uniprot id: A0A3P8ZD01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8010:slc26a5
gene id: 8010:slc26a5
uniprot id: A0A3P8Z6A9
uniprot id: A0A6Q2XQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8010:hoxa3a
gene id: 8010:hoxa3a
uniprot id: A0A3P8ZHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8010:LOC105012198
gene id: 8010:LOC105012198
uniprot id: A0A3P8X9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:map1lc3a
gene id: 8010:map1lc3a
uniprot id: A0A3P9A3N8
uniprot id: A0A6Q2YEN8
names: Similarity
messages: Belongs to the ATG8 family.

8010:galr2b
gene id: 8010:galr2b
uniprot id: A0A3P8YY37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:purab
gene id: 8010:purab
uniprot id: A0A3P8XUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8010:rab5if
gene id: 8010:rab5if
uniprot id: A0A3P8X7W1
names: Subcellular Location Annotation
messages: Membrane

8010:shfl
gene id: 8010:shfl
uniprot id: A0A6Q2YLF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

8010:ccdc124
gene id: 8010:ccdc124
uniprot id: A0A3P9AQE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

8010:si:ch211-282j22.3
gene id: 8010:si:ch211-282j22.3
uniprot id: A0A3P8XZI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8010:mocs2
gene id: 8010:mocs2
uniprot id: C1BXY0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

8010:hoxa11b
gene id: 8010:hoxa11b
uniprot id: A0A3P8XR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:tfe3a
gene id: 8010:tfe3a
uniprot id: A0A3P8YT87
uniprot id: A0A3P8YUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8010:lctlb
gene id: 8010:lctlb
uniprot id: A0A3P8X9M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8010:pabpc1b
gene id: 8010:pabpc1b
uniprot id: A0A3P8YER0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8010:setd2
gene id: 8010:setd2
uniprot id: A0A3P8Z9N8
names: Subcellular Location Annotation
messages: Nucleus

8010:nanog
gene id: 8010:nanog
uniprot id: A0A3P8YYG1
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105016216
gene id: 8010:LOC105016216
uniprot id: A0A6Q2ZIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:pknox2
gene id: 8010:pknox2
uniprot id: A0A3P8YHK9
uniprot id: A0A3P8YHS6
uniprot id: A0A3P9A5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:uox
gene id: 8010:uox
uniprot id: A0A3P9AL31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

8010:LOC105021893
gene id: 8010:LOC105021893
uniprot id: A0A3P9A3U8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:nipsnap1
gene id: 8010:nipsnap1
uniprot id: A0A3P8XER3
uniprot id: A0A3P8XHJ3
names: Similarity
messages: Belongs to the NipSnap family.

8010:gna11b
gene id: 8010:gna11b
uniprot id: A0A3P8XX48
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8010:LOC105016986
gene id: 8010:LOC105016986
uniprot id: A0A3P9AFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:sema5bb
gene id: 8010:sema5bb
uniprot id: A0A3P8X8E1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:itgb1a
gene id: 8010:itgb1a
uniprot id: A0A6Q2Z6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

8010:stk35
gene id: 8010:stk35
uniprot id: A0A3P8XBW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:si:ch1073-416d2.3
gene id: 8010:si:ch1073-416d2.3
uniprot id: A0A3P8XZZ0
names: Similarity
messages: Belongs to the serpin family.

8010:LOC105025666
gene id: 8010:LOC105025666
uniprot id: A0A3P8Z3N7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:paip2b
gene id: 8010:paip2b
uniprot id: A0A3P9ACU1
names: Similarity
messages: Belongs to the PAIP2 family.

8010:LOC105026002
gene id: 8010:LOC105026002
uniprot id: A0A3P9AN10
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8010:sptb
gene id: 8010:sptb
uniprot id: A0A3P9ALN7
uniprot id: A0A3P9ALQ2
uniprot id: A0A3P9ALS8
uniprot id: A0A3P9AMH0
names: Similarity
messages: Belongs to the spectrin family.

8010:mrpl46
gene id: 8010:mrpl46
uniprot id: A0A3P9A728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

8010:twf1b
gene id: 8010:twf1b
uniprot id: A0A3P9AIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8010:LOC105022657
gene id: 8010:LOC105022657
uniprot id: A0A3P8XDZ6
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8010:nampt1
gene id: 8010:nampt1
uniprot id: A0A3P9A9Z8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8010:slc7a6
gene id: 8010:slc7a6
uniprot id: A0A3P8YYN1
names: Subcellular Location Annotation
messages: Membrane

8010:atp1b2b
gene id: 8010:atp1b2b
uniprot id: A0A3P8XLX9
uniprot id: A0A3P8ZMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8010:ptp4a2a
gene id: 8010:ptp4a2a
uniprot id: A0A3P8ZHB4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8010:fez1
gene id: 8010:fez1
uniprot id: A0A3P8YII9
names: Similarity
messages: Belongs to the zygin family.

8010:impdh1b
gene id: 8010:impdh1b
uniprot id: A0A3P8X7B4
uniprot id: A0A3P8X9M9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8010:LOC105014149
gene id: 8010:LOC105014149
uniprot id: A0A3P8X7X1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:nlgn3a
gene id: 8010:nlgn3a
uniprot id: A0A3P8ZBX3
uniprot id: A0A3P9APM1
uniprot id: A0A3P9AQD4
uniprot id: A0A3P9AQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8010:polr3c
gene id: 8010:polr3c
uniprot id: A0A3P8Y8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8010:cibar1
gene id: 8010:cibar1
uniprot id: A0A3P8YKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole

8010:sntg1
gene id: 8010:sntg1
uniprot id: A0A3P8Z382
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8010:crabp1a
gene id: 8010:crabp1a
uniprot id: A0A3P9ANP5
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

8010:med7
gene id: 8010:med7
uniprot id: A0A3P8ZKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

8010:si:dkey-190g11.3
gene id: 8010:si:dkey-190g11.3
uniprot id: A0A3P8ZVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8010:slc7a8b
gene id: 8010:slc7a8b
uniprot id: A0A3P8XFY8
uniprot id: A0A3P8ZHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

8010:gabra2a
gene id: 8010:gabra2a
uniprot id: A0A3P8YDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

8010:cygb2
gene id: 8010:cygb2
uniprot id: A0A3P8XS05
names: Similarity
messages: Belongs to the globin family.

8010:LOC109615862
gene id: 8010:LOC109615862
uniprot id: A0A3P9AAY6
names: Subcellular Location Annotation
messages: Nucleus

8010:mycn
gene id: 8010:mycn
uniprot id: A0A3P8YIN3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8010:cxcr3.1
gene id: 8010:cxcr3.1
uniprot id: A0A3P9AEK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

8010:rab3gap2
gene id: 8010:rab3gap2
uniprot id: A0A3P8X8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

8010:LOC105022275
gene id: 8010:LOC105022275
uniprot id: A0A3P8XU91
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:ppp2cb
gene id: 8010:ppp2cb
uniprot id: A0A3P8YPB3
names: Similarity
messages: Belongs to the PPP phosphatase family.

8010:jag2b
gene id: 8010:jag2b
uniprot id: A0A3P8XLB0
uniprot id: A0A3P8XNS0
uniprot id: A0A3P8ZL82
uniprot id: A0A6Q2YQR2
uniprot id: A0A6Q2ZCW2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:LOC105027142
gene id: 8010:LOC105027142
uniprot id: A0A3P8XSH5
names: Similarity
messages: Belongs to the S-100 family.

8010:tenm1
gene id: 8010:tenm1
uniprot id: A0A3P8Y0P3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:aldh1a2
gene id: 8010:aldh1a2
uniprot id: A0A3P8YB02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:hprt1
gene id: 8010:hprt1
uniprot id: A0A3P8XYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8010:bcar1
gene id: 8010:bcar1
uniprot id: A0A3P8YJ50
uniprot id: A0A3P9A855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8010:LOC105023543
gene id: 8010:LOC105023543
uniprot id: A0A3P8XQH3
uniprot id: A0A3P8XQW9
names: Subcellular Location Annotation
messages: Nucleus

8010:mafbb
gene id: 8010:mafbb
uniprot id: A0A6Q2Y6F3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8010:LOC105031009
gene id: 8010:LOC105031009
uniprot id: A0A3P8ZYR9
uniprot id: A0A6Q2ZPW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

8010:wu:fa11c10
gene id: 8010:wu:fa11c10
uniprot id: A0A3P8XXW3
names: Similarity
messages: Belongs to the FAM110 family.

8010:LOC105018178
gene id: 8010:LOC105018178
uniprot id: A0A3P8YZA8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:zgc:153990
gene id: 8010:zgc:153990
uniprot id: A0A3P8YLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8010:LOC105029868
gene id: 8010:LOC105029868
uniprot id: A0A3P8YMM9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:LOC105024787
gene id: 8010:LOC105024787
uniprot id: A0A3P8ZYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8010:LOC105024007
gene id: 8010:LOC105024007
uniprot id: A0A3P8YI34
uniprot id: A0A3P8YJF3
uniprot id: A0A3P8YJY4
uniprot id: A0A3P9A7U5
uniprot id: A0A3P9A7V8
uniprot id: A0A6Q2ZJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8010:KEF92 p10
gene id: 8010:KEF92_p10
uniprot id: Q85D56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8010:adprh
gene id: 8010:adprh
uniprot id: A0A3P8Z6F0
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8010:tmem59
gene id: 8010:tmem59
uniprot id: A0A3P8YDE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:cdc14ab
gene id: 8010:cdc14ab
uniprot id: A0A3P8XCL7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

8010:tlcd3bb
gene id: 8010:tlcd3bb
uniprot id: A0A3P8Z4Q6
names: Subcellular Location Annotation
messages: Membrane

8010:ptk2bb
gene id: 8010:ptk2bb
uniprot id: A0A3P8XJZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8010:ppih
gene id: 8010:ppih
uniprot id: A0A3P8ZKQ4
uniprot id: A0A6Q2WZI8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:esrrb
gene id: 8010:esrrb
uniprot id: A0A3P8XNJ1
uniprot id: A0A3P8ZMK3
uniprot id: A0A3P8ZMU8
uniprot id: A0A3P8ZMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8010:cers2b
gene id: 8010:cers2b
uniprot id: A0A3P9A1Y3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:slc2a13b
gene id: 8010:slc2a13b
uniprot id: A0A3P8ZVW1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:mau2
gene id: 8010:mau2
uniprot id: A0A3P8XYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

8010:dynlrb1
gene id: 8010:dynlrb1
uniprot id: C1BY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

8010:fabp1a
gene id: 8010:fabp1a
uniprot id: A0A3P8YGN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8010:def8
gene id: 8010:def8
uniprot id: A0A3P8Y221
names: Similarity
messages: Belongs to the DEF8 family.

8010:sox4b
gene id: 8010:sox4b
uniprot id: A0A3P8XDR8
names: Subcellular Location Annotation
messages: Nucleus

8010:kalrna
gene id: 8010:kalrna
uniprot id: A0A3P9A3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

8010:LOC105013791
gene id: 8010:LOC105013791
uniprot id: A0A3P8Z2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

8010:LOC105029999
gene id: 8010:LOC105029999
uniprot id: A0A3P9A159
names: Similarity
messages: Belongs to the synapsin family.

8010:ppp3ca
gene id: 8010:ppp3ca
uniprot id: A0A3P8Z4U4
uniprot id: A0A3P8Z5P1
uniprot id: A0A3P9AL38
uniprot id: A0A6Q2YVY4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8010:crb1
gene id: 8010:crb1
uniprot id: A0A3P9AF39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:dlx3b
gene id: 8010:dlx3b
uniprot id: A0A3P8Y747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8010:nop53
gene id: 8010:nop53
uniprot id: A0A3P9AFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

8010:slco2b1
gene id: 8010:slco2b1
uniprot id: A0A3P8XJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8010:phactr1
gene id: 8010:phactr1
uniprot id: A0A3P8XBD1
uniprot id: A0A3P8ZBW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

8010:pdcl3
gene id: 8010:pdcl3
uniprot id: A0A3P8XVS6
names: Similarity
messages: Belongs to the phosducin family.

8010:slc43a1a
gene id: 8010:slc43a1a
uniprot id: A0A3P8ZBL7
names: Subcellular Location Annotation
messages: Membrane

8010:cops5
gene id: 8010:cops5
uniprot id: A0A3P8YFD8
uniprot id: A0A3P9A627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8010:neurl2
gene id: 8010:neurl2
uniprot id: A0A3P8YRT8
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105026739
gene id: 8010:LOC105026739
uniprot id: A0A3P8XTK3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:crebbpa
gene id: 8010:crebbpa
uniprot id: A0A3P9AK19
names: Subcellular Location Annotation
messages: Cytoplasm

8010:avpr2l
gene id: 8010:avpr2l
uniprot id: A0A3P8ZUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:ezh2
gene id: 8010:ezh2
uniprot id: A0A3P8ZW43
names: Subcellular Location Annotation
messages: Nucleus

8010:hbegfa
gene id: 8010:hbegfa
uniprot id: A0A3P8ZMS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105020329
gene id: 8010:LOC105020329
uniprot id: A0A3P9ALR2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8010:atp5f1c
gene id: 8010:atp5f1c
uniprot id: A0A3P8ZK03
uniprot id: C1BX87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

8010:kcnk1b
gene id: 8010:kcnk1b
uniprot id: A0A3P8Y4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8010:hk2
gene id: 8010:hk2
uniprot id: A0A3P8XJZ1
names: Similarity
messages: Belongs to the hexokinase family.

8010:sar1ab
gene id: 8010:sar1ab
uniprot id: A0A3P9AP42
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

8010:mdfic
gene id: 8010:mdfic
uniprot id: A0A3P8YCJ0
uniprot id: A0A3P8YCN6
names: Similarity
messages: Belongs to the MDFI family.

8010:tmem258
gene id: 8010:tmem258
uniprot id: A0A6Q2XLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8010:snrpa
gene id: 8010:snrpa
uniprot id: A0A3P8YDA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

8010:foxi3a
gene id: 8010:foxi3a
uniprot id: A0A3P9AKN1
names: Subcellular Location Annotation
messages: Nucleus

8010:orc6
gene id: 8010:orc6
uniprot id: A0A3P9AFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

8010:LOC105026796
gene id: 8010:LOC105026796
uniprot id: C1BY18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

8010:zgc:154093
gene id: 8010:zgc:154093
uniprot id: A0A3P8YPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8010:LOC105024194
gene id: 8010:LOC105024194
uniprot id: A0A6Q2YD59
names: Similarity
messages: Belongs to the DDA1 family.

8010:tbx5a
gene id: 8010:tbx5a
uniprot id: A0A3P8ZZP4
uniprot id: A0A3P9A1Z6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105021804
gene id: 8010:LOC105021804
uniprot id: A0A3P8ZPF4
names: Similarity
messages: Belongs to the filamin family.

8010:LOC105005877
gene id: 8010:LOC105005877
uniprot id: A0A3P8YRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:rps6ka3b
gene id: 8010:rps6ka3b
uniprot id: A0A3P8Y6E1
uniprot id: A0A3P8Y6F9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8010:gpr183b
gene id: 8010:gpr183b
uniprot id: A0A3P8ZDS5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:sgk1
gene id: 8010:sgk1
uniprot id: A0A3P8ZL27
uniprot id: A0A3P8ZM47
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:olfml2a
gene id: 8010:olfml2a
uniprot id: A0A3P8X7R6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:lamtor4
gene id: 8010:lamtor4
uniprot id: A0A3P8Y5S6
names: Similarity
messages: Belongs to the LAMTOR4 family.

8010:LOC105011262
gene id: 8010:LOC105011262
uniprot id: A0A3P8Z5S3
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8010:rbm8a
gene id: 8010:rbm8a
uniprot id: C1BXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

8010:shroom1
gene id: 8010:shroom1
uniprot id: A0A3P8Z8U1
uniprot id: A0A3P8Z9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8010:kcnab1b
gene id: 8010:kcnab1b
uniprot id: A0A3P8Y2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8010:nucb2a
gene id: 8010:nucb2a
uniprot id: A0A3P8ZTF0
names: Similarity
messages: Belongs to the nucleobindin family.

8010:pola2
gene id: 8010:pola2
uniprot id: A0A3P8ZKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

8010:epb41a
gene id: 8010:epb41a
uniprot id: A0A3P8YN44
uniprot id: A0A3P8YN58
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex

8010:c3h5orf22
gene id: 8010:c3h5orf22
uniprot id: A0A3P8Y9Z2
uniprot id: A0A3P9A0I2
names: Similarity
messages: Belongs to the UPF0489 family.

8010:LOC105016395
gene id: 8010:LOC105016395
uniprot id: A0A3P8XPV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105021626
gene id: 8010:LOC105021626
uniprot id: A0A3P8ZNY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8010:tnfrsf19
gene id: 8010:tnfrsf19
uniprot id: A0A3P9ABR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:arpin
gene id: 8010:arpin
uniprot id: A0A3P8YNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arpin family.
messages: lamellipodium

8010:atp2c1
gene id: 8010:atp2c1
uniprot id: A0A3P8XCK2
uniprot id: A0A3P8XCK6
uniprot id: A0A3P8ZGL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

8010:alpl
gene id: 8010:alpl
uniprot id: A0A3P8ZUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

8010:yme1l1b
gene id: 8010:yme1l1b
uniprot id: A0A3P8YHY8
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8010:LOC105023833
gene id: 8010:LOC105023833
uniprot id: A0A3P8Y0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8010:inhbaa
gene id: 8010:inhbaa
uniprot id: A0A3P8XFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8010:LOC105020686
gene id: 8010:LOC105020686
uniprot id: A0A3P8YDZ6
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8010:LOC105008781
gene id: 8010:LOC105008781
uniprot id: A0A3P8YPD1
names: Subcellular Location Annotation
messages: Membrane

8010:sirt4
gene id: 8010:sirt4
uniprot id: A0A3P8ZC82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

8010:gabrr2a
gene id: 8010:gabrr2a
uniprot id: A0A3P8Z9C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:mrpl2
gene id: 8010:mrpl2
uniprot id: A0A3P8XRY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8010:slc35a3a
gene id: 8010:slc35a3a
uniprot id: A0A3P8YFG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

8010:snrpd3
gene id: 8010:snrpd3
uniprot id: C1BY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8010:rab27b
gene id: 8010:rab27b
uniprot id: A0A3P8YEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8010:lpcat2
gene id: 8010:lpcat2
uniprot id: A0A3P8XJ22
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:LOC105024741
gene id: 8010:LOC105024741
uniprot id: A0A3P8ZF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8010:dynlrb2
gene id: 8010:dynlrb2
uniprot id: A0A6Q2WR60
uniprot id: C1BWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

8010:katna1
gene id: 8010:katna1
uniprot id: A0A3P8YTL8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8010:cmc1
gene id: 8010:cmc1
uniprot id: C1BXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8010:atxn2
gene id: 8010:atxn2
uniprot id: A0A3P9ADZ4
names: Similarity
messages: Belongs to the ataxin-2 family.

8010:lhfpl3
gene id: 8010:lhfpl3
uniprot id: A0A3P8X8H6
names: Subcellular Location Annotation
messages: Membrane

8010:zgc:101569
gene id: 8010:zgc:101569
uniprot id: A0A3P9AHH6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8010:LOC105012086
gene id: 8010:LOC105012086
uniprot id: A0A3P8Z1C2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8010:cisd2
gene id: 8010:cisd2
uniprot id: A0A3P8XHC3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

8010:LOC105018693
gene id: 8010:LOC105018693
uniprot id: A0A3P9APA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

8010:fam163ba
gene id: 8010:fam163ba
uniprot id: A0A6Q2YKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8010:atp5pf
gene id: 8010:atp5pf
uniprot id: C1BWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8010:adcy8
gene id: 8010:adcy8
uniprot id: A0A3P8YPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8010:b3gnt2b
gene id: 8010:b3gnt2b
uniprot id: A0A3P8YE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:cdh4
gene id: 8010:cdh4
uniprot id: A0A6Q2Y6K5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:shc1
gene id: 8010:shc1
uniprot id: A0A3P8Y6J2
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105026511
gene id: 8010:LOC105026511
uniprot id: A0A3P8YV57
names: Similarity
messages: Belongs to the KHDC4 family.

8010:LOC105022074
gene id: 8010:LOC105022074
uniprot id: A0A3P8YY27
names: Subcellular Location Annotation
messages: Membrane

8010:fam135b
gene id: 8010:fam135b
uniprot id: A0A3P8ZYH3
names: Similarity
messages: Belongs to the FAM135 family.

8010:mtmr10
gene id: 8010:mtmr10
uniprot id: A0A3P8YC74
uniprot id: A0A3P9A1I8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8010:erlec1
gene id: 8010:erlec1
uniprot id: A0A3P8ZWP9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

8010:mfap5
gene id: 8010:mfap5
uniprot id: A0A3P9A7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

8010:hikeshi
gene id: 8010:hikeshi
uniprot id: A0A3P8ZCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

8010:puf60b
gene id: 8010:puf60b
uniprot id: A0A3P8XLK5
uniprot id: A0A3P8XLM6
uniprot id: A0A3P8XQA7
uniprot id: A0A3P8ZME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8010:LOC105013532
gene id: 8010:LOC105013532
uniprot id: A0A3P8ZS44
names: Similarity
messages: Belongs to the TMEM9 family.

8010:LOC105019471
gene id: 8010:LOC105019471
uniprot id: A0A3P8ZAC1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105017137
gene id: 8010:LOC105017137
uniprot id: A0A3P9A4C6
names: Similarity
messages: Belongs to the RRM Spen family.

8010:zgc:101100
gene id: 8010:zgc:101100
uniprot id: A0A3P9A2C1
names: Subcellular Location Annotation
messages: Nucleus

8010:abcg1
gene id: 8010:abcg1
uniprot id: A0A3P8YKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8010:sh3gl3a
gene id: 8010:sh3gl3a
uniprot id: A0A3P8ZCS1
uniprot id: A0A6Q2XSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8010:LOC105021929
gene id: 8010:LOC105021929
uniprot id: A0A3P8ZG85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8010:esco2
gene id: 8010:esco2
uniprot id: A0A3P8Z6U0
names: Subcellular Location Annotation
messages: Nucleus

8010:arf2a
gene id: 8010:arf2a
uniprot id: A0A3P8YVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8010:gabpa
gene id: 8010:gabpa
uniprot id: A0A3P8YSQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105006329
gene id: 8010:LOC105006329
uniprot id: A0A3P8XZ24
uniprot id: A0A3P8ZTY9
names: Similarity
messages: Belongs to the serpin family.

8010:nid1a
gene id: 8010:nid1a
uniprot id: A0A3P8YSK3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8010:dnmbp
gene id: 8010:dnmbp
uniprot id: A0A3P8XDJ7
uniprot id: A0A3P8XGB3
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

8010:xrcc1
gene id: 8010:xrcc1
uniprot id: A0A3P8YKF6
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105024416
gene id: 8010:LOC105024416
uniprot id: A0A3P8ZJ11
names: Subcellular Location Annotation
messages: Membrane

8010:tatdn1
gene id: 8010:tatdn1
uniprot id: A0A3P9AB44
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8010:tollip
gene id: 8010:tollip
uniprot id: C1BZR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tollip family.
messages: Both ATG8-interaction motifs (AIM1 and AIM2) are required for the association with ATG8 family proteins.
messages: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity). In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity). Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P) (By similarity).
messages: Cytoplasm
messages: Early endosome
messages: Endosome
messages: Interacts with ATG8 family proteins (via AIM motifs), and ubiquitin (via CUE domain). Found in a complex with TOM1; interacts (via N-terminus) with TOM1 (via GAT domain); the interactions leads to TOM1-recruitment to endosomes and inhibition of TOLLIP binding to PtdIns(3)P (By similarity).
messages: The N-terminal TOM1-binding domain (residues 1-53) is a disordered domain that partially folds when bound to the GAT domain of TOM1.

8010:tpmt
gene id: 8010:tpmt
uniprot id: A0A3P8ZJA4
uniprot id: C1BXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

8010:anapc13
gene id: 8010:anapc13
uniprot id: C1BVZ6
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

8010:kif14
gene id: 8010:kif14
uniprot id: A0A3P8XIS0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:zgc:153031
gene id: 8010:zgc:153031
uniprot id: A0A3P9AG09
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

8010:gtf2f2b
gene id: 8010:gtf2f2b
uniprot id: A0A3P8XUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

8010:pigx
gene id: 8010:pigx
uniprot id: A0A3P8Y8U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:psmc6
gene id: 8010:psmc6
uniprot id: C1BZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8010:ogdhb
gene id: 8010:ogdhb
uniprot id: A0A3P8Z837
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8010:mpp2a
gene id: 8010:mpp2a
uniprot id: A0A3P9A2K5
names: Similarity
messages: Belongs to the MAGUK family.

8010:otx2b
gene id: 8010:otx2b
uniprot id: A0A3P8XT78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8010:bmp2b
gene id: 8010:bmp2b
uniprot id: A0A3P8Y8U4
names: Similarity
messages: Belongs to the TGF-beta family.

8010:LOC105027805
gene id: 8010:LOC105027805
uniprot id: A0A3P8Z581
uniprot id: A0A6Q2Y5R0
names: Similarity
messages: Belongs to the globin family.

8010:arpc1a
gene id: 8010:arpc1a
uniprot id: A0A3P8ZVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

8010:LOC105023145
gene id: 8010:LOC105023145
uniprot id: A0A3P8X8Q3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC109615981
gene id: 8010:LOC109615981
uniprot id: A0A3P8XSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

8010:LOC105026321
gene id: 8010:LOC105026321
uniprot id: A0A3P8YDX8
names: Similarity
messages: Belongs to the glutaminase family.

8010:LOC105019203
gene id: 8010:LOC105019203
uniprot id: A0A3P8XHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

8010:LOC105023762
gene id: 8010:LOC105023762
uniprot id: A0A6Q2ZER9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

8010:neto1l
gene id: 8010:neto1l
uniprot id: A0A3P8XBS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:stum
gene id: 8010:stum
uniprot id: A0A3P9APQ8
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105011466
gene id: 8010:LOC105011466
uniprot id: A0A3P8Z457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8010:sec63
gene id: 8010:sec63
uniprot id: A0A3P8XP42
names: Subcellular Location Annotation
messages: Membrane

8010:cdc42
gene id: 8010:cdc42
uniprot id: A0A3P8ZYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8010:acox3
gene id: 8010:acox3
uniprot id: A0A3P8ZU63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

8010:krr1
gene id: 8010:krr1
uniprot id: A0A3P8Z6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

8010:coro2bb
gene id: 8010:coro2bb
uniprot id: A0A3P8XDS6
names: Similarity
messages: Belongs to the WD repeat coronin family.

8010:LOC105025806
gene id: 8010:LOC105025806
uniprot id: C1BXA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

8010:LOC105014802
gene id: 8010:LOC105014802
uniprot id: A0A6Q2YI28
uniprot id: C1BW27
names: Similarity
messages: Belongs to the CDK2AP family.

8010:cmbl
gene id: 8010:cmbl
uniprot id: C1BWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8010:tlx1
gene id: 8010:tlx1
uniprot id: A0A3P8YH32
uniprot id: A0A6Q2YC09
names: Subcellular Location Annotation
messages: Nucleus

8010:dmrt1
gene id: 8010:dmrt1
uniprot id: A0A6Q2ZG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8010:LOC105010452
gene id: 8010:LOC105010452
uniprot id: A0A3P8XEN5
uniprot id: A0A3P8ZHM1
names: Similarity
messages: Belongs to the spectrin family.

8010:dio3b
gene id: 8010:dio3b
uniprot id: A0A224MMI4
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

8010:LOC105016297
gene id: 8010:LOC105016297
uniprot id: A0A3P8XLH0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:gorab
gene id: 8010:gorab
uniprot id: A0A3P9AGZ0
names: Similarity
messages: Belongs to the GORAB family.

8010:LOC105013373
gene id: 8010:LOC105013373
uniprot id: C1BYD3
names: Similarity
messages: Belongs to the globin family.

8010:ubr1
gene id: 8010:ubr1
uniprot id: A0A3P8XW72
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8010:tmcc2
gene id: 8010:tmcc2
uniprot id: A0A3P9A3L5
names: Similarity
messages: Belongs to the TEX28 family.

8010:arhgap32b
gene id: 8010:arhgap32b
uniprot id: A0A3P8YFB4
uniprot id: A0A3P8YGU3
uniprot id: A0A3P8YH88
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

8010:cyc
gene id: 8010:cyc
uniprot id: C1BYU9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8010:ppm1aa
gene id: 8010:ppm1aa
uniprot id: A0A3P8Y260
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8010:usp48
gene id: 8010:usp48
uniprot id: A0A3P8XP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

8010:plppr2b
gene id: 8010:plppr2b
uniprot id: A0A3P9AP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8010:LOC105010548
gene id: 8010:LOC105010548
uniprot id: A0A3P8ZJC5
names: Similarity
messages: Belongs to the BicC family.

8010:pdk1
gene id: 8010:pdk1
uniprot id: A0A3P9AKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8010:ccdc86
gene id: 8010:ccdc86
uniprot id: A0A3P9AKV0
names: Subcellular Location Annotation
messages: Nucleus

8010:bcat1
gene id: 8010:bcat1
uniprot id: A0A3P8YT18
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

8010:adrm1
gene id: 8010:adrm1
uniprot id: A0A3P9A9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105016383
gene id: 8010:LOC105016383
uniprot id: A0A3P8ZQG2
names: Similarity
messages: Belongs to the TCTP family.

8010:cadm2b
gene id: 8010:cadm2b
uniprot id: A0A3P9APZ6
uniprot id: A0A3P9AQL7
names: Similarity
messages: Belongs to the nectin family.

8010:znf592
gene id: 8010:znf592
uniprot id: A0A3P8YSG0
uniprot id: A0A3P9ADS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

8010:entpd8
gene id: 8010:entpd8
uniprot id: A0A3P8XCS1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8010:si:ch211-246m6.5
gene id: 8010:si:ch211-246m6.5
uniprot id: A0A3P9A555
uniprot id: A0A3P9A674
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:en1a
gene id: 8010:en1a
uniprot id: A0A3P8XNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8010:ccnb2
gene id: 8010:ccnb2
uniprot id: A0A3P8Y9P2
names: Similarity
messages: Belongs to the cyclin family.

8010:LOC105029553
gene id: 8010:LOC105029553
uniprot id: A0A6Q2ZME9
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:si:dkey-264d12.4
gene id: 8010:si:dkey-264d12.4
uniprot id: A0A3P8Z7K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:gale
gene id: 8010:gale
uniprot id: A0A3P8XAG2
uniprot id: C1BWV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

8010:LOC105012755
gene id: 8010:LOC105012755
uniprot id: A0A3P8Y6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:LOC105024100
gene id: 8010:LOC105024100
uniprot id: A0A3P8YW52
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

8010:nav1a
gene id: 8010:nav1a
uniprot id: A0A3P8YGZ6
names: Similarity
messages: Belongs to the Nav/unc-53 family.

8010:LOC105010141
gene id: 8010:LOC105010141
uniprot id: A0A3P8Y4H5
uniprot id: A0A3P8Y4M4
uniprot id: A0A3P8Y518
uniprot id: A0A3P8ZY83
uniprot id: A0A6Q2X6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

8010:epha7
gene id: 8010:epha7
uniprot id: A0A3P9AB13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:sardh
gene id: 8010:sardh
uniprot id: A0A3P8ZM94
names: Similarity
messages: Belongs to the GcvT family.

8010:LOC105030381
gene id: 8010:LOC105030381
uniprot id: A0A3P8Z7B3
uniprot id: A0A6Q2WSW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8010:polb
gene id: 8010:polb
uniprot id: A0A3P8ZSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

8010:rpa2
gene id: 8010:rpa2
uniprot id: A0A3P9AD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

8010:cdc42bpb
gene id: 8010:cdc42bpb
uniprot id: A0A3P8YRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

8010:LOC105015522
gene id: 8010:LOC105015522
uniprot id: C1BX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8010:usp16
gene id: 8010:usp16
uniprot id: A0A3P8ZAS8
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:mc4r
gene id: 8010:mc4r
uniprot id: A0A3P8ZZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

8010:LOC105020468
gene id: 8010:LOC105020468
uniprot id: A0A3P9AB88
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8010:LOC105018310
gene id: 8010:LOC105018310
uniprot id: A0A6Q2XJE5
names: Similarity
messages: Belongs to the pyruvate kinase family.

8010:cenpl
gene id: 8010:cenpl
uniprot id: A0A6Q2Z8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

8010:cmtm7
gene id: 8010:cmtm7
uniprot id: C1BYX2
names: Subcellular Location Annotation
messages: Membrane

8010:angptl4
gene id: 8010:angptl4
uniprot id: A0A3P9AFQ4
names: Subcellular Location Annotation
messages: Secreted

8010:mcur1
gene id: 8010:mcur1
uniprot id: A0A3P8YJR5
names: Similarity
messages: Belongs to the CCDC90 family.

8010:gtpbp10
gene id: 8010:gtpbp10
uniprot id: A0A3P8Y395
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

8010:casq1a
gene id: 8010:casq1a
uniprot id: A0A3P8ZHL8
uniprot id: A0A6Q2X5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8010:LOC105010717
gene id: 8010:LOC105010717
uniprot id: A0A3P8YRF7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105029303
gene id: 8010:LOC105029303
uniprot id: A0A3P8ZV27
names: Subcellular Location Annotation
messages: Secreted

8010:LOC105031192
gene id: 8010:LOC105031192
uniprot id: A0A3P9AGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8010:rec8b
gene id: 8010:rec8b
uniprot id: A0A3P8YZ98
names: Subcellular Location Annotation
messages: Nucleus

8010:hspb11
gene id: 8010:hspb11
uniprot id: C1BXD1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8010:shroom2b
gene id: 8010:shroom2b
uniprot id: A0A3P8YNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8010:LOC105028446
gene id: 8010:LOC105028446
uniprot id: C1BY22
names: Similarity
messages: Belongs to the globin family.

8010:lin7b
gene id: 8010:lin7b
uniprot id: A0A3P8XM77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8010:LOC105019354
gene id: 8010:LOC105019354
uniprot id: A0A3P8ZL43
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:ctsc
gene id: 8010:ctsc
uniprot id: A0A3P8ZX66
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

8010:rnf13
gene id: 8010:rnf13
uniprot id: A0A3P8ZIC6
names: Subcellular Location Annotation
messages: Membrane

8010:akap8l
gene id: 8010:akap8l
uniprot id: A0A3P8ZZI5
names: Similarity
messages: Belongs to the AKAP95 family.

8010:LOC105026671
gene id: 8010:LOC105026671
uniprot id: A0A3P9A2K4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:myo1ea
gene id: 8010:myo1ea
uniprot id: A0A3P8YAE8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8010:mmp20a
gene id: 8010:mmp20a
uniprot id: A0A3P8YM85
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:LOC105018644
gene id: 8010:LOC105018644
uniprot id: A0A3P8ZH29
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:cldn1
gene id: 8010:cldn1
uniprot id: A0A3P8Z6E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:mboat7
gene id: 8010:mboat7
uniprot id: A0A3P9A530
names: Subcellular Location Annotation
messages: Membrane

8010:enkur
gene id: 8010:enkur
uniprot id: A0A3P8Z2F9
names: Subcellular Location Annotation
messages: cilium axoneme

8010:bace1
gene id: 8010:bace1
uniprot id: A0A3P8XV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

8010:LOC105018735
gene id: 8010:LOC105018735
uniprot id: A0A3P9A8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

8010:sephs1
gene id: 8010:sephs1
uniprot id: A0A3P9AK05
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

8010:LOC105013074
gene id: 8010:LOC105013074
uniprot id: A0A3P9ALX2
uniprot id: A0A3P9AN08
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:cndp2
gene id: 8010:cndp2
uniprot id: A0A3P8YGV0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8010:csf3a
gene id: 8010:csf3a
uniprot id: A0A3P8ZXD8
names: Similarity
messages: Belongs to the IL-6 superfamily.

8010:dll4
gene id: 8010:dll4
uniprot id: A0A3P8YZM0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:jak2b
gene id: 8010:jak2b
uniprot id: A0A6Q2Y1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Endomembrane system
messages: Nucleus

8010:ezrb
gene id: 8010:ezrb
uniprot id: A0A6Q2Z756
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8010:tshz3b
gene id: 8010:tshz3b
uniprot id: A0A3P9AGC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8010:si:dkey-112m2.1
gene id: 8010:si:dkey-112m2.1
uniprot id: A0A3P8Y230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8010:elovl7b
gene id: 8010:elovl7b
uniprot id: A0A3P9AB20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:dyrk1b
gene id: 8010:dyrk1b
uniprot id: A0A3P9AKK2
uniprot id: A0A6Q2YXD3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8010:tbcc
gene id: 8010:tbcc
uniprot id: C1BYH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

8010:LOC105009168
gene id: 8010:LOC105009168
uniprot id: A0A3P9AND3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8010:nr1d1
gene id: 8010:nr1d1
uniprot id: A0A3P8YEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:atp2a2b
gene id: 8010:atp2a2b
uniprot id: A0A3P8XZI2
uniprot id: A0A3P8ZU55
uniprot id: A0A6Q2X0M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8010:LOC105017334
gene id: 8010:LOC105017334
uniprot id: A0A3P8XJJ4
names: Similarity
messages: Belongs to the TGF-beta family.

8010:vdac2
gene id: 8010:vdac2
uniprot id: A0A3P8Z6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

8010:LOC105025533
gene id: 8010:LOC105025533
uniprot id: A0A3P8YXJ5
names: Similarity
messages: Belongs to the DeSI family.

8010:LOC105015080
gene id: 8010:LOC105015080
uniprot id: A0A3P8Y910
uniprot id: A0A6Q2Y1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8010:creb3l3b
gene id: 8010:creb3l3b
uniprot id: A0A3P8XRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105024786
gene id: 8010:LOC105024786
uniprot id: A0A3P8Y8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:ppm1db
gene id: 8010:ppm1db
uniprot id: A0A3P9AI93
names: Similarity
messages: Belongs to the PP2C family.

8010:pdx1
gene id: 8010:pdx1
uniprot id: A0A6Q2XUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8010:sema6bb
gene id: 8010:sema6bb
uniprot id: A0A3P8YGV9
uniprot id: A0A3P9A5X6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:dapk2b
gene id: 8010:dapk2b
uniprot id: A0A3P8XCM4
uniprot id: A0A3P8XGW6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:atp5mc3b
gene id: 8010:atp5mc3b
uniprot id: A0A6Q2WS98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8010:LOC105018284
gene id: 8010:LOC105018284
uniprot id: A0A3P8ZUA6
names: Subcellular Location Annotation
messages: Nucleus

8010:si:cabz01007807.1
gene id: 8010:si:cabz01007807.1
uniprot id: A0A3P8XUR5
names: Similarity
messages: Belongs to the apolipoprotein L family.

8010:abcc4
gene id: 8010:abcc4
uniprot id: A0A3P8Z657
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8010:fabp7b
gene id: 8010:fabp7b
uniprot id: C1BYI1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:foxj1b
gene id: 8010:foxj1b
uniprot id: A0A3P8YT40
names: Subcellular Location Annotation
messages: Nucleus

8010:hoxb8a
gene id: 8010:hoxb8a
uniprot id: A0A3P8YF94
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105007222
gene id: 8010:LOC105007222
uniprot id: A0A3P8ZJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8010:smim8
gene id: 8010:smim8
uniprot id: C1BW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

8010:sept5a
gene id: 8010:sept5a
uniprot id: A0A3P8XV47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: cytoskeleton

8010:LOC105029938
gene id: 8010:LOC105029938
uniprot id: A0A3P8YRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:kcnj16
gene id: 8010:kcnj16
uniprot id: A0A6Q2Z0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8010:psme3
gene id: 8010:psme3
uniprot id: A0A3P8XQE2
names: Similarity
messages: Belongs to the PA28 family.

8010:cstf2
gene id: 8010:cstf2
uniprot id: A0A3P8XDQ1
uniprot id: A0A3P8XGH0
names: Subcellular Location Annotation
messages: Nucleus

8010:dyrk4
gene id: 8010:dyrk4
uniprot id: A0A3P8YBL5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8010:avl9
gene id: 8010:avl9
uniprot id: A0A3P8ZPQ2
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

8010:wwox
gene id: 8010:wwox
uniprot id: A0A3P9AME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm

8010:LOC105009887
gene id: 8010:LOC105009887
uniprot id: A0A3P8XI81
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8010:fgf13b
gene id: 8010:fgf13b
uniprot id: A0A3P8Z9F7
uniprot id: A0A3P8ZAD0
uniprot id: A0A3P8ZAX1
uniprot id: A0A3P8ZAY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

8010:LOC105027987
gene id: 8010:LOC105027987
uniprot id: A0A3P9AM57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC109616314
gene id: 8010:LOC109616314
uniprot id: A0A3P9AIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

8010:snx8a
gene id: 8010:snx8a
uniprot id: A0A3P8YWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8010:ndufb2
gene id: 8010:ndufb2
uniprot id: A0A3P8XAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:loxl5b
gene id: 8010:loxl5b
uniprot id: A0A3P9A2U1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8010:uncx
gene id: 8010:uncx
uniprot id: A0A3P9AH74
names: Subcellular Location Annotation
messages: Nucleus

8010:pusl1
gene id: 8010:pusl1
uniprot id: A0A3P8YJK7
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8010:qtrt2
gene id: 8010:qtrt2
uniprot id: A0A3P8YB96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

8010:hapln3
gene id: 8010:hapln3
uniprot id: A0A3P8XDH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:pcyt1bb
gene id: 8010:pcyt1bb
uniprot id: A0A3P9AHS8
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8010:hspb1
gene id: 8010:hspb1
uniprot id: A0A3P8YY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

8010:LOC105027304
gene id: 8010:LOC105027304
uniprot id: C1BXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8010:LOC105020905
gene id: 8010:LOC105020905
uniprot id: A0A3P9A0T7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:mpl
gene id: 8010:mpl
uniprot id: A0A3P8Z216
uniprot id: A0A3P9AI04
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

8010:crot
gene id: 8010:crot
uniprot id: A0A3P8XZ63
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8010:dhcr7
gene id: 8010:dhcr7
uniprot id: A0A3P9AHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8010:LOC105029521
gene id: 8010:LOC105029521
uniprot id: A0A3P8ZZ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8010:pyroxd1
gene id: 8010:pyroxd1
uniprot id: A0A3P8ZX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

8010:LOC105011942
gene id: 8010:LOC105011942
uniprot id: A0A3P8XBE8
names: Subcellular Location Annotation
messages: cytoskeleton

8010:stx3a
gene id: 8010:stx3a
uniprot id: A0A3P8X8K8
uniprot id: A0A3P8XCK5
names: Similarity
messages: Belongs to the syntaxin family.

8010:LOC105024558
gene id: 8010:LOC105024558
uniprot id: A0A3P8Y4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8010:mmp11a
gene id: 8010:mmp11a
uniprot id: A0A3P8X7Q5
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:cct4
gene id: 8010:cct4
uniprot id: A0A3P9A0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8010:hsd17b12a
gene id: 8010:hsd17b12a
uniprot id: A0A3P8XFK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:lim2.5
gene id: 8010:lim2.5
uniprot id: A0A3P8YJD0
uniprot id: A0A3P9A8M6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:qars1
gene id: 8010:qars1
uniprot id: A0A3P9APW1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8010:frem1a
gene id: 8010:frem1a
uniprot id: A0A3P8YK11
names: Similarity
messages: Belongs to the FRAS1 family.

8010:mapk8b
gene id: 8010:mapk8b
uniprot id: A0A3P8ZL54
uniprot id: A0A6Q2WYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8010:LOC105020242
gene id: 8010:LOC105020242
uniprot id: A0A3P8XQK9
uniprot id: A0A3P8ZMT7
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8010:fgf13a
gene id: 8010:fgf13a
uniprot id: A0A3P8XBT7
uniprot id: A0A3P8XBW4
uniprot id: A0A3P8XEQ3
uniprot id: A0A3P8XES9
uniprot id: A0A3P8XG81
uniprot id: A0A3P8ZEU6
uniprot id: A0A6Q2YJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

8010:oxsm
gene id: 8010:oxsm
uniprot id: A0A3P8XWN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

8010:fgf7
gene id: 8010:fgf7
uniprot id: A0A3P8ZG03
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:si:cabz01101003.1
gene id: 8010:si:cabz01101003.1
uniprot id: A0A3P8XUJ6
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8010:LOC105022408
gene id: 8010:LOC105022408
uniprot id: A0A3P8Z082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8010:LOC109615161
gene id: 8010:LOC109615161
uniprot id: A0A3P8ZWA7
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:LOC105025774
gene id: 8010:LOC105025774
uniprot id: A0A3P8XVY8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:snx33
gene id: 8010:snx33
uniprot id: A0A3P8Z705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8010:LOC105030787
gene id: 8010:LOC105030787
uniprot id: A0A3P8Z3E0
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

8010:pitx1
gene id: 8010:pitx1
uniprot id: A0A6Q2YBS0
uniprot id: A0A6Q2YX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8010:LOC105027041
gene id: 8010:LOC105027041
uniprot id: A0A3P9AIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:brinp3a.1
gene id: 8010:brinp3a.1
uniprot id: A0A3P8XBJ4
names: Similarity
messages: Belongs to the BRINP family.

8010:kiaa2013
gene id: 8010:kiaa2013
uniprot id: A0A3P8XUV6
uniprot id: A0A3P8ZSG3
uniprot id: A0A6Q2X4P2
names: Subcellular Location Annotation
messages: Membrane

8010:syngr2b
gene id: 8010:syngr2b
uniprot id: A0A3P8YRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8010:rom1a
gene id: 8010:rom1a
uniprot id: A0A3P9A8X0
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

8010:kdm5a
gene id: 8010:kdm5a
uniprot id: A0A3P8ZRN3
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8010:smx5
gene id: 8010:smx5
uniprot id: A0A3P8XUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

8010:LOC105023857
gene id: 8010:LOC105023857
uniprot id: A0A3P8Y5P7
uniprot id: A0A3P8ZX65
uniprot id: A0A3P8ZX84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8010:sparc
gene id: 8010:sparc
uniprot id: A0A3P9AL32
names: Similarity
messages: Belongs to the SPARC family.

8010:atp11c
gene id: 8010:atp11c
uniprot id: A0A3P8XAY2
uniprot id: A0A3P8XF81
uniprot id: A0A3P8ZFR2
uniprot id: A0A6Q2XPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8010:chmp6b
gene id: 8010:chmp6b
uniprot id: C1BWA5
names: Similarity
messages: Belongs to the SNF7 family.

8010:rpl12
gene id: 8010:rpl12
uniprot id: A0A3P8YXS9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8010:pknox1.2
gene id: 8010:pknox1.2
uniprot id: A0A3P8Z033
uniprot id: A0A3P9AHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:apaf1
gene id: 8010:apaf1
uniprot id: A0A3P8ZBQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

8010:si:ch211-112c15.8
gene id: 8010:si:ch211-112c15.8
uniprot id: A0A3P8ZQE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105012897
gene id: 8010:LOC105012897
uniprot id: A0A3P8Z003
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:chrna5
gene id: 8010:chrna5
uniprot id: A0A3P8YK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:ddx61
gene id: 8010:ddx61
uniprot id: A0A3P9AGE8
uniprot id: A0A3P9AHG7
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:c17h1orf74
gene id: 8010:c17h1orf74
uniprot id: A0A3P8X8E4
names: Similarity
messages: Belongs to the UPF0739 family.

8010:ppp2r5a
gene id: 8010:ppp2r5a
uniprot id: A0A3P9A378
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8010:med8
gene id: 8010:med8
uniprot id: A0A3P8X996
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

8010:si:ch211-217a12.1
gene id: 8010:si:ch211-217a12.1
uniprot id: A0A3P8YHL3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8010:dolpp1
gene id: 8010:dolpp1
uniprot id: A0A3P8Z4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

8010:prkcdb
gene id: 8010:prkcdb
uniprot id: A0A3P8ZM85
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8010:LOC105026348
gene id: 8010:LOC105026348
uniprot id: A0A3P8YBB4
names: Similarity
messages: Belongs to the CATSPERD family.

8010:LOC105028918
gene id: 8010:LOC105028918
uniprot id: A0A3P9ANT2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8010:atp1b1a
gene id: 8010:atp1b1a
uniprot id: A0A3P8ZQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8010:csad
gene id: 8010:csad
uniprot id: A0A3P8YRR1
uniprot id: A0A3P9ADB2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8010:LOC105024740
gene id: 8010:LOC105024740
uniprot id: A0A3P8XCG0
uniprot id: A0A3P8ZG73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8010:LOC105016698
gene id: 8010:LOC105016698
uniprot id: A0A3P9A6V4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8010:grm3
gene id: 8010:grm3
uniprot id: A0A3P8YXV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

8010:avpr1aa
gene id: 8010:avpr1aa
uniprot id: A0A3P8XRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:LOC105018113
gene id: 8010:LOC105018113
uniprot id: A0A3P9A456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:rps4x
gene id: 8010:rps4x
uniprot id: C1BZ31
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

8010:LOC105022750
gene id: 8010:LOC105022750
uniprot id: A0A3P8YV51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

8010:suox
gene id: 8010:suox
uniprot id: A0A3P8YYT8
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

8010:LOC105030081
gene id: 8010:LOC105030081
uniprot id: A0A3P8XX47
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:slc7a10b
gene id: 8010:slc7a10b
uniprot id: A0A3P9AAK1
names: Subcellular Location Annotation
messages: Membrane

8010:rnf34b
gene id: 8010:rnf34b
uniprot id: A0A3P8YYH6
uniprot id: A0A3P8Z069
names: Subcellular Location Annotation
messages: Cell membrane

8010:galnt3
gene id: 8010:galnt3
uniprot id: A0A3P8YWB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:nup98
gene id: 8010:nup98
uniprot id: A0A3P8XIX9
uniprot id: A0A3P8XJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

8010:slc30a4
gene id: 8010:slc30a4
uniprot id: A0A3P8XED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8010:pdgfrb
gene id: 8010:pdgfrb
uniprot id: A0A3P8YJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:prdx6
gene id: 8010:prdx6
uniprot id: A0A3P8XSQ9
uniprot id: A0A6Q2XEQ3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8010:mmp24
gene id: 8010:mmp24
uniprot id: A0A6Q2Y3E3
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:chrnb4
gene id: 8010:chrnb4
uniprot id: A0A3P8YMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:gls2b
gene id: 8010:gls2b
uniprot id: A0A3P9AEK8
names: Similarity
messages: Belongs to the glutaminase family.

8010:lpl
gene id: 8010:lpl
uniprot id: A0A3P8Z4R7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8010:pld3
gene id: 8010:pld3
uniprot id: A0A3P9A0A5
names: Similarity
messages: Belongs to the phospholipase D family.

8010:otud7b
gene id: 8010:otud7b
uniprot id: A0A3P8Y667
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:trap1
gene id: 8010:trap1
uniprot id: A0A3P8YJ65
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8010:pmvk
gene id: 8010:pmvk
uniprot id: A0A3P8XVI5
names: Subcellular Location Annotation
messages: cytosol

8010:mogs
gene id: 8010:mogs
uniprot id: A0A3P9AQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

8010:LOC105020115
gene id: 8010:LOC105020115
uniprot id: A0A3P8ZEG1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:pbx1b
gene id: 8010:pbx1b
uniprot id: A0A3P8X993
uniprot id: A0A3P8ZD26
uniprot id: A0A3P8ZD36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8010:prim2
gene id: 8010:prim2
uniprot id: A0A3P8YYZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

8010:exosc9
gene id: 8010:exosc9
uniprot id: A0A3P8Y256
names: Subcellular Location Annotation
messages: Cytoplasm

8010:tmem30b
gene id: 8010:tmem30b
uniprot id: A0A3P9A4W5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8010:drd4a
gene id: 8010:drd4a
uniprot id: A0A3P8XKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:prss16
gene id: 8010:prss16
uniprot id: A0A3P9A5L3
names: Similarity
messages: Belongs to the peptidase S28 family.

8010:lrrfip1a
gene id: 8010:lrrfip1a
uniprot id: A0A3P8XYL9
uniprot id: A0A3P8ZTH0
names: Similarity
messages: Belongs to the LRRFIP family.

8010:cct8
gene id: 8010:cct8
uniprot id: A0A3P8ZTX3
uniprot id: A0A3P8ZUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8010:tnfrsf1a
gene id: 8010:tnfrsf1a
uniprot id: A0A3P8YPL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:gtf2h5
gene id: 8010:gtf2h5
uniprot id: C1BY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

8010:rnf8
gene id: 8010:rnf8
uniprot id: A0A3P8Y8T8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.
messages: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins. In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
messages: Homodimer. Forms a E2-E3 ubiquitin ligase complex composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2.
messages: Nucleus
messages: The FHA domain specifically recognizes and binds ATM-phosphorylated MDC1.

8010:slc35c1
gene id: 8010:slc35c1
uniprot id: A0A3P9AIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

8010:kif11
gene id: 8010:kif11
uniprot id: A0A3P8XK68
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:mat2ab
gene id: 8010:mat2ab
uniprot id: A0A3P8YDQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8010:mtg2
gene id: 8010:mtg2
uniprot id: A0A3P8YL84
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

8010:prdm6
gene id: 8010:prdm6
uniprot id: A0A3P8ZPP3
uniprot id: A0A3P8ZPQ3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105028967
gene id: 8010:LOC105028967
uniprot id: A0A3P8YI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:cldn11a
gene id: 8010:cldn11a
uniprot id: A0A3P8XMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:hcar1-3
gene id: 8010:hcar1-3
uniprot id: A0A3P9A7D1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:tada2a
gene id: 8010:tada2a
uniprot id: A0A3P8Z493
names: Subcellular Location Annotation
messages: Nucleus

8010:ndrg1a
gene id: 8010:ndrg1a
uniprot id: A0A3P8Z2P2
uniprot id: A0A3P9AK15
uniprot id: A0A6Q2XP75
names: Similarity
messages: Belongs to the NDRG family.

8010:zgc:162612
gene id: 8010:zgc:162612
uniprot id: A0A3P8XYJ6
names: Subcellular Location Annotation
messages: Nucleus

8010:aspa
gene id: 8010:aspa
uniprot id: A0A3P8Z4W5
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8010:six4a
gene id: 8010:six4a
uniprot id: A0A3P8Y2C1
names: Subcellular Location Annotation
messages: Nucleus

8010:cfl1
gene id: 8010:cfl1
uniprot id: C1BXW2
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8010:LOC105012656
gene id: 8010:LOC105012656
uniprot id: A0A3P8YEA1
names: Similarity
messages: Belongs to the mTERF family.

8010:cacng7a
gene id: 8010:cacng7a
uniprot id: A0A3P9AKL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8010:tagln
gene id: 8010:tagln
uniprot id: A0A3P8ZRK8
uniprot id: C1BXJ5
uniprot id: C1BYA5
names: Similarity
messages: Belongs to the calponin family.

8010:LOC105006659
gene id: 8010:LOC105006659
uniprot id: A0A3P8ZKJ5
uniprot id: A0A3P8ZLM4
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105015695
gene id: 8010:LOC105015695
uniprot id: A0A6Q2X1Q4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:osbpl7
gene id: 8010:osbpl7
uniprot id: A0A3P8ZRH2
uniprot id: A0A3P8ZRI5
names: Similarity
messages: Belongs to the OSBP family.

8010:tlr2
gene id: 8010:tlr2
uniprot id: A0A3P8XUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

8010:LOC105013729
gene id: 8010:LOC105013729
uniprot id: A0A3P9AG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8010:zgc:113425
gene id: 8010:zgc:113425
uniprot id: A0A3P8ZD75
names: Similarity
messages: Belongs to the MS4A family.

8010:rhot2
gene id: 8010:rhot2
uniprot id: A0A3P8ZT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8010:uchl5
gene id: 8010:uchl5
uniprot id: A0A3P8XB75
uniprot id: A0A3P8ZFF2
names: Similarity
messages: Belongs to the peptidase C12 family.

8010:anpepa
gene id: 8010:anpepa
uniprot id: A0A3P8YMG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8010:LOC105018278
gene id: 8010:LOC105018278
uniprot id: A0A3P8ZV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

8010:zpd
gene id: 8010:zpd
uniprot id: A0A3P9A438
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:htr2aa
gene id: 8010:htr2aa
uniprot id: A0A3P8ZRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

8010:coq7
gene id: 8010:coq7
uniprot id: C1BWP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

8010:ro60
gene id: 8010:ro60
uniprot id: A0A3P8XJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

8010:mrpl3
gene id: 8010:mrpl3
uniprot id: C1BYK9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8010:stx1b
gene id: 8010:stx1b
uniprot id: A0A3P8YG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

8010:LOC105010888
gene id: 8010:LOC105010888
uniprot id: A0A3P8Z301
names: Similarity
messages: Belongs to the GDNFR family.

8010:acp5a
gene id: 8010:acp5a
uniprot id: A0A3P9AQ38
names: Cofactor
messages: Binds 2 iron ions per subunit.

8010:gpr61
gene id: 8010:gpr61
uniprot id: A0A3P8YJC7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:ripply1
gene id: 8010:ripply1
uniprot id: A0A3P8XRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

8010:slc47a3
gene id: 8010:slc47a3
uniprot id: A0A3P9AIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8010:gpd1c
gene id: 8010:gpd1c
uniprot id: A0A3P8YXQ0
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8010:tnc
gene id: 8010:tnc
uniprot id: A0A3P8XE65
uniprot id: A0A3P8ZGM5
uniprot id: A0A3P8ZGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

8010:hs3st2
gene id: 8010:hs3st2
uniprot id: A0A3P8YZB0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:prr15la
gene id: 8010:prr15la
uniprot id: A0A3P8YCW0
names: Similarity
messages: Belongs to the PRR15 family.

8010:LOC105007752
gene id: 8010:LOC105007752
uniprot id: A0A3P8XQQ3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:rps14
gene id: 8010:rps14
uniprot id: C1BW23
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8010:chst3a
gene id: 8010:chst3a
uniprot id: A0A3P9A0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8010:cxcr2
gene id: 8010:cxcr2
uniprot id: A0A3P8YMX4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:dlb
gene id: 8010:dlb
uniprot id: A0A3P8YLV6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:LOC105019970
gene id: 8010:LOC105019970
uniprot id: A0A6Q2XFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8010:LOC105019845
gene id: 8010:LOC105019845
uniprot id: A0A3P8XFY1
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:zhx3
gene id: 8010:zhx3
uniprot id: A0A3P8XBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8010:tmem161b
gene id: 8010:tmem161b
uniprot id: A0A3P9A7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8010:cenpj
gene id: 8010:cenpj
uniprot id: A0A3P8ZJG5
names: Similarity
messages: Belongs to the TCP10 family.

8010:tbx22
gene id: 8010:tbx22
uniprot id: A0A3P8XHI0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:nfs1
gene id: 8010:nfs1
uniprot id: A0A3P8YXH1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

8010:lft1
gene id: 8010:lft1
uniprot id: A0A3P8Y3E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8010:cdk5r2b
gene id: 8010:cdk5r2b
uniprot id: A0A3P9A4T1
names: Similarity
messages: Belongs to the cyclin-dependent kinase 5 activator family.

8010:LOC105007210
gene id: 8010:LOC105007210
uniprot id: A0A3P8XWQ7
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:LOC105021666
gene id: 8010:LOC105021666
uniprot id: A0A3P8Z239
names: Similarity
messages: Belongs to the FAM214 family.

8010:mmp13b
gene id: 8010:mmp13b
uniprot id: A0A3P8YLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Secreted

8010:si:ch73-141c7.1
gene id: 8010:si:ch73-141c7.1
uniprot id: A0A3P8YU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8010:LOC105009247
gene id: 8010:LOC105009247
uniprot id: A0A3P8YDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8010:snw1
gene id: 8010:snw1
uniprot id: A0A3P8ZN79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8010:prtfdc1a
gene id: 8010:prtfdc1a
uniprot id: A0A3P8Z290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8010:LOC105029205
gene id: 8010:LOC105029205
uniprot id: A0A3P8YWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8010:LOC105014543
gene id: 8010:LOC105014543
uniprot id: A0A3P8Z481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8010:pdhb
gene id: 8010:pdhb
uniprot id: C1BXA8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

8010:LOC105007420
gene id: 8010:LOC105007420
uniprot id: A0A3P8ZE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:timp2a
gene id: 8010:timp2a
uniprot id: A0A3P8YRW3
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8010:ss18
gene id: 8010:ss18
uniprot id: A0A3P8YQ60
uniprot id: A0A3P8YQ65
names: Similarity
messages: Belongs to the SS18 family.

8010:zgc:113363
gene id: 8010:zgc:113363
uniprot id: A0A3P8YV90
names: Similarity
messages: Belongs to the MDFI family.

8010:twsg1a
gene id: 8010:twsg1a
uniprot id: A0A3P8ZM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

8010:mtrf1l
gene id: 8010:mtrf1l
uniprot id: A0A3P8XDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8010:zgc:152830
gene id: 8010:zgc:152830
uniprot id: A0A3P8XT58
names: Similarity
messages: Belongs to the peptidase M17 family.

8010:prpf4ba
gene id: 8010:prpf4ba
uniprot id: A0A3P9A9Q0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

8010:si:dkey-91m11.5
gene id: 8010:si:dkey-91m11.5
uniprot id: A0A3P8X7C7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8010:pan2
gene id: 8010:pan2
uniprot id: A0A3P8ZAC7
uniprot id: A0A3P8ZAI1
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

8010:rae1
gene id: 8010:rae1
uniprot id: A0A3P8ZJM9
uniprot id: A0A6Q2X5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

8010:pold1
gene id: 8010:pold1
uniprot id: A0A3P8Y8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8010:adrb2a
gene id: 8010:adrb2a
uniprot id: A0A3P8ZNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:celf3a
gene id: 8010:celf3a
uniprot id: A0A3P8XPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105026811
gene id: 8010:LOC105026811
uniprot id: A0A3P8YMI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ppp1r9a
gene id: 8010:ppp1r9a
uniprot id: A0A3P8YVH2
uniprot id: A0A3P8YVK3
uniprot id: A0A3P9AFS9
names: Subcellular Location Annotation
messages: cytoskeleton

8010:tango6
gene id: 8010:tango6
uniprot id: A0A3P9A420
names: Similarity
messages: Belongs to the Tango6 family.

8010:themis
gene id: 8010:themis
uniprot id: A0A3P9AFI0
names: Similarity
messages: Belongs to the themis family.

8010:rpl13
gene id: 8010:rpl13
uniprot id: A0A3P8YD11
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

8010:hoxb13a
gene id: 8010:hoxb13a
uniprot id: A0A3P8YFD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:naxd
gene id: 8010:naxd
uniprot id: A0A6Q2WR02
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

8010:agt
gene id: 8010:agt
uniprot id: A0A3P8YCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

8010:ppef1
gene id: 8010:ppef1
uniprot id: A0A3P8Y5D6
names: Similarity
messages: Belongs to the PPP phosphatase family.

8010:taf6l
gene id: 8010:taf6l
uniprot id: A0A3P9A047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8010:acsf3
gene id: 8010:acsf3
uniprot id: A0A3P8YQG1
uniprot id: A0A3P8YQI2
uniprot id: A0A3P8YRR5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:LOC105012177
gene id: 8010:LOC105012177
uniprot id: A0A3P9APW6
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:grm8b
gene id: 8010:grm8b
uniprot id: A0A6Q2YU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8010:hgfa
gene id: 8010:hgfa
uniprot id: A0A3P8ZCM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

8010:bzw1a
gene id: 8010:bzw1a
uniprot id: A0A3P8YI63
names: Similarity
messages: Belongs to the BZW family.

8010:ywhag1
gene id: 8010:ywhag1
uniprot id: A0A3P9AGD2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8010:praf2
gene id: 8010:praf2
uniprot id: C1BYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8010:serinc2l
gene id: 8010:serinc2l
uniprot id: A0A3P9A626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8010:aarsd1
gene id: 8010:aarsd1
uniprot id: A0A3P8XTS7
uniprot id: A0A3P8ZP72
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

8010:porb
gene id: 8010:porb
uniprot id: A0A3P8YI54
uniprot id: A0A3P8YJH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

8010:LOC105024595
gene id: 8010:LOC105024595
uniprot id: A0A3P8YE51
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:gdf11
gene id: 8010:gdf11
uniprot id: A0A3P9AIC2
names: Similarity
messages: Belongs to the TGF-beta family.

8010:LOC105026473
gene id: 8010:LOC105026473
uniprot id: A0A3P8ZDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:wnt16
gene id: 8010:wnt16
uniprot id: A0A3P8XZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:LOC105005972
gene id: 8010:LOC105005972
uniprot id: A0A3P8ZLX9
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:twf1a
gene id: 8010:twf1a
uniprot id: A0A3P8ZS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8010:sh3bp4
gene id: 8010:sh3bp4
uniprot id: A0A3P8XEQ0
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

8010:LOC105006832
gene id: 8010:LOC105006832
uniprot id: A0A3P8XRI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:LOC105017692
gene id: 8010:LOC105017692
uniprot id: A0A3P8ZNH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8010:smug1
gene id: 8010:smug1
uniprot id: A0A3P9AF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

8010:magi1b
gene id: 8010:magi1b
uniprot id: A0A3P8XPH5
uniprot id: A0A3P8XRP9
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105007495
gene id: 8010:LOC105007495
uniprot id: A0A3P8ZX83
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

8010:LOC105006002
gene id: 8010:LOC105006002
uniprot id: A0A3P9AJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8010:trmt2b
gene id: 8010:trmt2b
uniprot id: A0A3P9APX6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105021604
gene id: 8010:LOC105021604
uniprot id: A0A3P8ZRU7
names: Similarity
messages: Belongs to the Rho GDI family.

8010:prr5a
gene id: 8010:prr5a
uniprot id: A0A3P8Z942
names: Similarity
messages: Belongs to the PROTOR family.

8010:f3a
gene id: 8010:f3a
uniprot id: A0A3P8ZCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8010:glra4a
gene id: 8010:glra4a
uniprot id: A0A3P8YI46
uniprot id: A0A3P8YJU2
uniprot id: A0A3P8YJV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8010:gpd1l
gene id: 8010:gpd1l
uniprot id: A0A3P8X9P1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8010:fbxo45
gene id: 8010:fbxo45
uniprot id: A0A3P8X873
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

8010:LOC105015131
gene id: 8010:LOC105015131
uniprot id: A0A3P8ZN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

8010:cdh7a
gene id: 8010:cdh7a
uniprot id: A0A3P8ZK64
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:agpat9l
gene id: 8010:agpat9l
uniprot id: A0A3P8ZGU2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:LOC105015619
gene id: 8010:LOC105015619
uniprot id: A0A3P8XGX5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8010:ing5a
gene id: 8010:ing5a
uniprot id: C1BXW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8010:cenpn
gene id: 8010:cenpn
uniprot id: A0A3P8Y1Y0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

8010:LOC105030023
gene id: 8010:LOC105030023
uniprot id: A0A3P8XXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:LOC105013835
gene id: 8010:LOC105013835
uniprot id: A0A3P8XMQ9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:scn5lab
gene id: 8010:scn5lab
uniprot id: A0A3P8YQ59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

8010:xpr1a
gene id: 8010:xpr1a
uniprot id: A0A3P8XUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

8010:cfdp1
gene id: 8010:cfdp1
uniprot id: A0A3P9A6V1
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

8010:slc17a9b
gene id: 8010:slc17a9b
uniprot id: A0A3P8X7G6
names: Subcellular Location Annotation
messages: Membrane

8010:eif4e2rs1
gene id: 8010:eif4e2rs1
uniprot id: C1BW58
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8010:LOC105015058
gene id: 8010:LOC105015058
uniprot id: A0A6Q2XUY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:atp6v1h
gene id: 8010:atp6v1h
uniprot id: A0A3P8ZR24
uniprot id: A0A3P8ZRZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8010:ppox
gene id: 8010:ppox
uniprot id: A0A3P9ALM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

8010:sdr42e2
gene id: 8010:sdr42e2
uniprot id: A0A3P8XH20
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8010:LOC105025223
gene id: 8010:LOC105025223
uniprot id: A0A3P8YLP5
names: Subcellular Location Annotation
messages: Nucleus

8010:si:ch211-63o20.7
gene id: 8010:si:ch211-63o20.7
uniprot id: A0A3P8ZRI6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:b3gnt5b
gene id: 8010:b3gnt5b
uniprot id: A0A3P9APG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:ehd2a
gene id: 8010:ehd2a
uniprot id: A0A3P9AEZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8010:LOC105020073
gene id: 8010:LOC105020073
uniprot id: A0A6Q2Z6R9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

8010:tafa5a
gene id: 8010:tafa5a
uniprot id: A0A3P8XUW8
uniprot id: A0A3P8XV04
names: Similarity
messages: Belongs to the TAFA family.

8010:LOC105025773
gene id: 8010:LOC105025773
uniprot id: A0A3P8XSS4
uniprot id: A0A3P8XUS8
names: Subcellular Location Annotation
messages: Membrane

8010:agpat2
gene id: 8010:agpat2
uniprot id: A0A3P8XAW1
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

8010:polr1f
gene id: 8010:polr1f
uniprot id: A0A3P8XEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

8010:zmpste24
gene id: 8010:zmpste24
uniprot id: A0A3P8YCY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

8010:sema4ab
gene id: 8010:sema4ab
uniprot id: A0A3P8YHQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ddah1
gene id: 8010:ddah1
uniprot id: A0A3P9ALQ7
uniprot id: A0A3P9AMN9
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8010:eny2
gene id: 8010:eny2
uniprot id: C1BWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8010:spns3
gene id: 8010:spns3
uniprot id: A0A3P9AHR0
uniprot id: A0A6Q2XZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8010:cdk5
gene id: 8010:cdk5
uniprot id: A0A3P9AK11
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:tspan7
gene id: 8010:tspan7
uniprot id: A0A3P8XDZ3
uniprot id: C1BZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:ppt1
gene id: 8010:ppt1
uniprot id: C1BYI2
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

8010:carm1
gene id: 8010:carm1
uniprot id: A0A3P8Z8R9
uniprot id: A0A6Q2ZHM7
names: Subcellular Location Annotation
messages: Nucleus

8010:mmp23ba
gene id: 8010:mmp23ba
uniprot id: A0A3P8YJV5
uniprot id: A0A6Q2WYI5
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:atad2b
gene id: 8010:atad2b
uniprot id: A0A3P8YAL4
names: Similarity
messages: Belongs to the AAA ATPase family.

8010:parp2
gene id: 8010:parp2
uniprot id: A0A3P8XDR0
uniprot id: A0A3P8XGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8010:LOC105007163
gene id: 8010:LOC105007163
uniprot id: A0A3P8Z647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8010:tmem126a
gene id: 8010:tmem126a
uniprot id: C1BWW6
names: Subcellular Location Annotation
messages: Membrane

8010:efna1b
gene id: 8010:efna1b
uniprot id: A0A3P8Y497
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:cpox
gene id: 8010:cpox
uniprot id: A0A3P9A3V3
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

8010:orc1
gene id: 8010:orc1
uniprot id: A0A3P8Z029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

8010:cryba1b
gene id: 8010:cryba1b
uniprot id: A0A3P8XN40
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:LOC105022573
gene id: 8010:LOC105022573
uniprot id: A0A6Q2YT03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:ngfrb
gene id: 8010:ngfrb
uniprot id: A0A3P8Z949
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:miga2
gene id: 8010:miga2
uniprot id: A0A3P9ALP5
names: Similarity
messages: Belongs to the mitoguardin family.

8010:LOC105031446
gene id: 8010:LOC105031446
uniprot id: A0A3P9APD3
names: Similarity
messages: Belongs to the Bcl-2 family.

8010:onecutl
gene id: 8010:onecutl
uniprot id: A0A3P8ZX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8010:cd79a
gene id: 8010:cd79a
uniprot id: C1BZC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:areg
gene id: 8010:areg
uniprot id: A0A3P9AN69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:lpcat3
gene id: 8010:lpcat3
uniprot id: A0A3P8YTB9
names: Subcellular Location Annotation
messages: Membrane

8010:pde4ba
gene id: 8010:pde4ba
uniprot id: A0A3P9ALN3
uniprot id: A0A3P9ALQ0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:LOC105021421
gene id: 8010:LOC105021421
uniprot id: A0A3P8XJC0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:LOC105010709
gene id: 8010:LOC105010709
uniprot id: A0A3P8YL29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:c20h8orf37
gene id: 8010:c20h8orf37
uniprot id: A0A3P8XXF2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

8010:slc24a5
gene id: 8010:slc24a5
uniprot id: A0A3P8ZFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:LOC105015142
gene id: 8010:LOC105015142
uniprot id: A0A3P8XR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8010:LOC105020257
gene id: 8010:LOC105020257
uniprot id: A0A3P8XTN8
uniprot id: A0A3P8ZRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

8010:jmy
gene id: 8010:jmy
uniprot id: A0A3P8XQA1
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105021496
gene id: 8010:LOC105021496
uniprot id: A0A3P8Y0X9
names: Similarity
messages: Belongs to the hexokinase family.

8010:LOC105027628
gene id: 8010:LOC105027628
uniprot id: A0A3P8Y044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8010:dyrk1ab
gene id: 8010:dyrk1ab
uniprot id: A0A3P9AFB1
uniprot id: A0A6Q2ZKZ6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8010:pdia4
gene id: 8010:pdia4
uniprot id: A0A3P8Y0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8010:rock1
gene id: 8010:rock1
uniprot id: A0A3P8Z788
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

8010:prkg1b
gene id: 8010:prkg1b
uniprot id: A0A3P8XAL9
uniprot id: A0A3P8ZF33
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8010:LOC106024600
gene id: 8010:LOC106024600
uniprot id: A0A3P8XAC6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:c1galt1a
gene id: 8010:c1galt1a
uniprot id: A0A3P8XVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

8010:elapor1
gene id: 8010:elapor1
uniprot id: A0A3P8ZXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8010:LOC105019402
gene id: 8010:LOC105019402
uniprot id: A0A3P8ZH60
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:sh3bgr
gene id: 8010:sh3bgr
uniprot id: A0A3P8YRE8
uniprot id: A0A3P8YRF9
uniprot id: A0A3P8YRH1
uniprot id: A0A3P8YRK8
uniprot id: A0A3P8YSQ4
uniprot id: A0A3P9ABN6
uniprot id: A0A3P9AD07
uniprot id: A0A3P9AD37
uniprot id: A0A3P9AD41
names: Similarity
messages: Belongs to the SH3BGR family.

8010:foxd5
gene id: 8010:foxd5
uniprot id: A0A3P8ZCG4
names: Subcellular Location Annotation
messages: Nucleus

8010:fuca2
gene id: 8010:fuca2
uniprot id: A0A3P9AC93
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

8010:sv2bb
gene id: 8010:sv2bb
uniprot id: A0A3P8Y215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8010:pax7a
gene id: 8010:pax7a
uniprot id: A0A3P8Y611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8010:slc1a3a
gene id: 8010:slc1a3a
uniprot id: A0A3P8YZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:sucla2
gene id: 8010:sucla2
uniprot id: A0A3P8ZSU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

8010:mgat1b
gene id: 8010:mgat1b
uniprot id: A0A3P9AA39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8010:mical2b
gene id: 8010:mical2b
uniprot id: A0A3P8YEX9
uniprot id: A0A3P8YFK0
uniprot id: A0A3P8YGF1
uniprot id: A0A3P8YH04
uniprot id: A0A3P8YH74
uniprot id: A0A3P9A4F3
uniprot id: A0A3P9A5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8010:LOC105012327
gene id: 8010:LOC105012327
uniprot id: A0A3P9AB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

8010:nup205
gene id: 8010:nup205
uniprot id: A0A3P8YR83
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

8010:LOC105006891
gene id: 8010:LOC105006891
uniprot id: A0A6Q2X4V6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8010:stxbp1a
gene id: 8010:stxbp1a
uniprot id: A0A3P8XVZ2
uniprot id: A0A3P8ZSZ3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8010:nadka
gene id: 8010:nadka
uniprot id: A0A3P8YKE2
uniprot id: A0A3P8YMQ2
names: Similarity
messages: Belongs to the NAD kinase family.

8010:tle5
gene id: 8010:tle5
uniprot id: A0A3P8YKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8010:triqk
gene id: 8010:triqk
uniprot id: A0A6Q2YXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:hoxb7a
gene id: 8010:hoxb7a
uniprot id: C1BZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:ube4a
gene id: 8010:ube4a
uniprot id: A0A3P8YFX4
uniprot id: A0A6Q2YXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8010:LOC105014505
gene id: 8010:LOC105014505
uniprot id: A0A3P9AQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105016363
gene id: 8010:LOC105016363
uniprot id: A0A3P8XST9
names: Similarity
messages: Belongs to the SH3RF family.

8010:ybey
gene id: 8010:ybey
uniprot id: C1BXD7
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

8010:lars2
gene id: 8010:lars2
uniprot id: A0A3P9AQD0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8010:crata
gene id: 8010:crata
uniprot id: A0A3P9AEP2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8010:pnrc2
gene id: 8010:pnrc2
uniprot id: A0A3P8YLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

8010:vps16
gene id: 8010:vps16
uniprot id: A0A3P8XE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

8010:gabrd
gene id: 8010:gabrd
uniprot id: A0A3P8YNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:tmem59l
gene id: 8010:tmem59l
uniprot id: A0A3P8YQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:czib
gene id: 8010:czib
uniprot id: A0A6Q2X1Z7
names: Similarity
messages: Belongs to the UPF0587 family.

8010:mtnr1ba
gene id: 8010:mtnr1ba
uniprot id: Q9DG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8010:si:ch211-191a24.4
gene id: 8010:si:ch211-191a24.4
uniprot id: A0A3P9APV9
names: Subcellular Location Annotation
messages: Membrane

8010:slc7a6os
gene id: 8010:slc7a6os
uniprot id: A0A3P9AFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

8010:lpcat4
gene id: 8010:lpcat4
uniprot id: A0A3P8XXM6
uniprot id: A0A6Q2ZAL7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:pdcl
gene id: 8010:pdcl
uniprot id: A0A3P8XAR9
names: Similarity
messages: Belongs to the phosducin family.

8010:cryl1
gene id: 8010:cryl1
uniprot id: A0A3P8XM52
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8010:cldn15lb
gene id: 8010:cldn15lb
uniprot id: A0A3P9AI90
uniprot id: A0A3P9AJA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:ndufa7
gene id: 8010:ndufa7
uniprot id: A0A3P8X9K3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

8010:cdca5
gene id: 8010:cdca5
uniprot id: A0A3P8YK18
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8010:mical1
gene id: 8010:mical1
uniprot id: A0A3P8XNY6
uniprot id: A0A3P8ZKB9
uniprot id: A0A3P8ZKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8010:ptger1a
gene id: 8010:ptger1a
uniprot id: A0A3P8ZA67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105023863
gene id: 8010:LOC105023863
uniprot id: A0A3P8Y4M0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:bdkrb1
gene id: 8010:bdkrb1
uniprot id: A0A3P8ZLD2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105010646
gene id: 8010:LOC105010646
uniprot id: A0A3P8ZPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8010:aldh6a1
gene id: 8010:aldh6a1
uniprot id: A0A3P8XRQ6
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8010:cdkn1ca
gene id: 8010:cdkn1ca
uniprot id: A0A3P9AHL5
names: Similarity
messages: Belongs to the CDI family.

8010:slc44a2
gene id: 8010:slc44a2
uniprot id: A0A3P8ZAF3
uniprot id: A0A3P8ZAF8
uniprot id: A0A6Q2XQJ7
uniprot id: A0A6Q2ZDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8010:plod1a
gene id: 8010:plod1a
uniprot id: A0A3P8XHN5
uniprot id: A0A3P8XLV4
uniprot id: A0A3P8ZJL6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8010:slc35b2
gene id: 8010:slc35b2
uniprot id: A0A3P8YAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8010:nup93
gene id: 8010:nup93
uniprot id: A0A3P9A7C1
uniprot id: A0A6Q2YGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

8010:nipal3
gene id: 8010:nipal3
uniprot id: A0A3P8YG74
uniprot id: A0A3P9A5E6
uniprot id: A0A6Q2XFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8010:fam49al
gene id: 8010:fam49al
uniprot id: A0A3P8YSQ5
uniprot id: A0A3P8YTV4
uniprot id: A0A3P9ACK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8010:olah
gene id: 8010:olah
uniprot id: C1BWG6
names: Similarity
messages: Belongs to the thioesterase family.

8010:rars1
gene id: 8010:rars1
uniprot id: A0A3P8ZVL3
uniprot id: A0A6Q2X6R0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8010:plekha8
gene id: 8010:plekha8
uniprot id: A0A3P8XPY9
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

8010:srrt
gene id: 8010:srrt
uniprot id: A0A3P8XQW3
names: Similarity
messages: Belongs to the ARS2 family.

8010:ptger2a
gene id: 8010:ptger2a
uniprot id: A0A3P9A5Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:mst1
gene id: 8010:mst1
uniprot id: A0A3P8XUT0
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105021680
gene id: 8010:LOC105021680
uniprot id: A0A3P9A6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

8010:gch2
gene id: 8010:gch2
uniprot id: A0A3P8ZD59
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8010:prkcea
gene id: 8010:prkcea
uniprot id: A0A3P8ZD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8010:ipmkb
gene id: 8010:ipmkb
uniprot id: A0A3P8XA77
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:zgc:85777
gene id: 8010:zgc:85777
uniprot id: A0A3P9AFF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:gadd45ab
gene id: 8010:gadd45ab
uniprot id: A0A3P8X9S1
uniprot id: A0A6Q2X2U1
names: Similarity
messages: Belongs to the GADD45 family.

8010:six3a
gene id: 8010:six3a
uniprot id: A0A3P8ZZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8010:kcns3a
gene id: 8010:kcns3a
uniprot id: A0A3P9A9X1
names: Subcellular Location Annotation
messages: Membrane

8010:stx11a
gene id: 8010:stx11a
uniprot id: A0A3P8YTV9
names: Similarity
messages: Belongs to the syntaxin family.

8010:gtpbp1
gene id: 8010:gtpbp1
uniprot id: A0A3P8XI39
uniprot id: A0A3P8ZGZ3
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

8010:LOC105016359
gene id: 8010:LOC105016359
uniprot id: A0A3P8XWG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:LOC105019692
gene id: 8010:LOC105019692
uniprot id: A0A3P9APK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105016035
gene id: 8010:LOC105016035
uniprot id: A0A3P8YCQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8010:ccnyl1
gene id: 8010:ccnyl1
uniprot id: A0A3P8ZK53
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8010:sox19b
gene id: 8010:sox19b
uniprot id: A0A3P8XYK2
uniprot id: A0A3P8Y1H6
names: Subcellular Location Annotation
messages: Nucleus

8010:tmeff1b
gene id: 8010:tmeff1b
uniprot id: A0A3P9AAK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105030780
gene id: 8010:LOC105030780
uniprot id: A0A3P8ZMA5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:slc25a6
gene id: 8010:slc25a6
uniprot id: A0A3P8Y495
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8010:flvcr2a
gene id: 8010:flvcr2a
uniprot id: A0A3P8ZMV4
names: Subcellular Location Annotation
messages: Membrane

8010:ptges
gene id: 8010:ptges
uniprot id: C1BYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8010:srsf2a
gene id: 8010:srsf2a
uniprot id: A0A3P8Z8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

8010:LOC105018873
gene id: 8010:LOC105018873
uniprot id: A0A3P8XDV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:lrrfip1b
gene id: 8010:lrrfip1b
uniprot id: A0A3P8X9H8
uniprot id: A0A3P8X9L4
uniprot id: A0A3P8ZD24
names: Similarity
messages: Belongs to the LRRFIP family.

8010:penkb
gene id: 8010:penkb
uniprot id: A0A3P9AI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

8010:LOC105010060
gene id: 8010:LOC105010060
uniprot id: A0A3P8YSC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:chst11
gene id: 8010:chst11
uniprot id: A0A3P8XL28
uniprot id: A0A3P8ZIY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:brinp3a.2
gene id: 8010:brinp3a.2
uniprot id: A0A3P8XBI2
names: Similarity
messages: Belongs to the BRINP family.

8010:chrnb5a
gene id: 8010:chrnb5a
uniprot id: A0A3P8Y3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:LOC105029721
gene id: 8010:LOC105029721
uniprot id: A0A3P8ZMJ4
uniprot id: A0A6Q2X890
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8010:c20h1orf43
gene id: 8010:c20h1orf43
uniprot id: A0A3P8Y2D4
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

8010:LOC105009375
gene id: 8010:LOC105009375
uniprot id: A0A3P9A470
names: Similarity
messages: Belongs to the peptidase C64 family.

8010:LOC105009716
gene id: 8010:LOC105009716
uniprot id: A0A3P8ZPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

8010:hpgd
gene id: 8010:hpgd
uniprot id: A0A3P9A1F4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:nkx2.1
gene id: 8010:nkx2.1
uniprot id: A0A3P8Z0U1
names: Subcellular Location Annotation
messages: Nucleus

8010:rffl
gene id: 8010:rffl
uniprot id: A0A3P8YL65
uniprot id: A0A3P9A8P2
names: Subcellular Location Annotation
messages: Cell membrane

8010:irf7
gene id: 8010:irf7
uniprot id: A0A3P8ZH33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:ccn5
gene id: 8010:ccn5
uniprot id: A0A3P8XLG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:aasdh
gene id: 8010:aasdh
uniprot id: A0A3P8ZH08
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:cnot8
gene id: 8010:cnot8
uniprot id: A0A3P8Y176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8010:senp6b
gene id: 8010:senp6b
uniprot id: A0A3P9A250
names: Similarity
messages: Belongs to the peptidase C48 family.

8010:pik3r2
gene id: 8010:pik3r2
uniprot id: A0A3P8YXY6
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8010:LOC105023875
gene id: 8010:LOC105023875
uniprot id: A0A3P8ZYZ4
uniprot id: A0A6Q2XME0
names: Similarity
messages: Belongs to the intermediate filament family.

8010:gphnb
gene id: 8010:gphnb
uniprot id: A0A3P8XUW0
uniprot id: A0A3P8ZQY0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

8010:pdia3
gene id: 8010:pdia3
uniprot id: A0A3P8XF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8010:gbp
gene id: 8010:gbp
uniprot id: C1BY60
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

8010:mrps33
gene id: 8010:mrps33
uniprot id: C1BYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

8010:LOC105026922
gene id: 8010:LOC105026922
uniprot id: A0A3P8Y7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8010:LOC105010732
gene id: 8010:LOC105010732
uniprot id: A0A3P8YD90
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8010:echdc2
gene id: 8010:echdc2
uniprot id: A0A3P8XQC8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8010:LOC105018179
gene id: 8010:LOC105018179
uniprot id: A0A3P9AHF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:abcg2d
gene id: 8010:abcg2d
uniprot id: A0A3P8YG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8010:ttc1
gene id: 8010:ttc1
uniprot id: A0A3P8Z389
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:marveld2b
gene id: 8010:marveld2b
uniprot id: A0A3P8XR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:cks2
gene id: 8010:cks2
uniprot id: A0A3P8YMN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8010:LOC105022870
gene id: 8010:LOC105022870
uniprot id: A0A3P8YZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8010:psmd9
gene id: 8010:psmd9
uniprot id: C1BW95
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8010:atg13
gene id: 8010:atg13
uniprot id: A0A3P8Z3Y0
uniprot id: A0A3P8Z469
uniprot id: A0A3P9ALD8
uniprot id: A0A6Q2XG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

8010:mical3b
gene id: 8010:mical3b
uniprot id: A0A3P8Y6N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Nucleus
messages: cytoskeleton

8010:LOC105016048
gene id: 8010:LOC105016048
uniprot id: A0A3P9A270
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105014807
gene id: 8010:LOC105014807
uniprot id: A0A3P8XAN0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:man2b1
gene id: 8010:man2b1
uniprot id: A0A3P9AJY0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8010:scin
gene id: 8010:scin
uniprot id: A0A3P9AMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: cytoskeleton
messages: podosome

8010:pnpla8
gene id: 8010:pnpla8
uniprot id: A0A3P8ZUG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105016545
gene id: 8010:LOC105016545
uniprot id: A0A6Q2YNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8010:eif1ad
gene id: 8010:eif1ad
uniprot id: A0A6Q2ZK18
names: Similarity
messages: Belongs to the EIF1AD family.

8010:edil3a
gene id: 8010:edil3a
uniprot id: A0A3P8YKG8
uniprot id: A0A3P8YKH8
uniprot id: A0A3P8YKI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:asrgl1
gene id: 8010:asrgl1
uniprot id: A0A3P8Y6E8
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8010:ap1m2
gene id: 8010:ap1m2
uniprot id: A0A3P9AM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8010:agtrap
gene id: 8010:agtrap
uniprot id: A0A3P8Y0X8
names: Subcellular Location Annotation
messages: Membrane

8010:gng13b
gene id: 8010:gng13b
uniprot id: A0A6Q2WPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:LOC105026423
gene id: 8010:LOC105026423
uniprot id: A0A3P8ZPE3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

8010:tmem9b
gene id: 8010:tmem9b
uniprot id: A0A3P8ZRB4
names: Similarity
messages: Belongs to the TMEM9 family.

8010:LOC105017038
gene id: 8010:LOC105017038
uniprot id: A0A3P9ACL7
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

8010:LOC105012286
gene id: 8010:LOC105012286
uniprot id: A0A3P8ZJS5
names: Similarity
messages: Belongs to the IFT56 family.

8010:rab9a
gene id: 8010:rab9a
uniprot id: A0A3P9A7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8010:sumo3b
gene id: 8010:sumo3b
uniprot id: A0A3P8Y1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8010:LOC105016288
gene id: 8010:LOC105016288
uniprot id: A0A3P8XL71
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:ric3b
gene id: 8010:ric3b
uniprot id: A0A3P8ZHJ8
names: Similarity
messages: Belongs to the ric-3 family.

8010:ecsit
gene id: 8010:ecsit
uniprot id: A0A3P8Y9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

8010:kxd1
gene id: 8010:kxd1
uniprot id: A0A3P8ZIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

8010:hoga1
gene id: 8010:hoga1
uniprot id: A0A3P9AE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

8010:eif4h
gene id: 8010:eif4h
uniprot id: A0A3P8YL05
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

8010:litaf
gene id: 8010:litaf
uniprot id: A0A3P9AGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

8010:LOC105012483
gene id: 8010:LOC105012483
uniprot id: A0A3P8ZF54
names: Similarity
messages: Belongs to the aerolysin family.

8010:hapln1a
gene id: 8010:hapln1a
uniprot id: A0A3P9A9C7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:fgf10a
gene id: 8010:fgf10a
uniprot id: A0A3P8ZDA9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:g6pc3
gene id: 8010:g6pc3
uniprot id: A0A3P9A6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8010:LOC105008572
gene id: 8010:LOC105008572
uniprot id: A0A3P8YC35
uniprot id: A0A3P9A1Z7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:stac3
gene id: 8010:stac3
uniprot id: A0A3P9A3B2
names: Subcellular Location Annotation
messages: sarcolemma

8010:fam189a2
gene id: 8010:fam189a2
uniprot id: A0A6Q2YXS7
names: Similarity
messages: Belongs to the ENTREP family.

8010:LOC105018056
gene id: 8010:LOC105018056
uniprot id: A0A6Q2Z226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8010:st8sia6
gene id: 8010:st8sia6
uniprot id: A0A3P9A8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:zgc:162989
gene id: 8010:zgc:162989
uniprot id: C1BWF8
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8010:LOC105012881
gene id: 8010:LOC105012881
uniprot id: A0A6Q2XBC6
names: Subcellular Location Annotation
messages: Membrane

8010:plaub
gene id: 8010:plaub
uniprot id: A0A3P8Y4X8
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

8010:LOC105029796
gene id: 8010:LOC105029796
uniprot id: A0A3P8Z5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8010:pdss1
gene id: 8010:pdss1
uniprot id: A0A3P8XRZ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8010:LOC105024384
gene id: 8010:LOC105024384
uniprot id: A0A3P8Z7D5
uniprot id: A0A3P9AMY7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:LOC105021464
gene id: 8010:LOC105021464
uniprot id: A0A3P8XWI3
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105017806
gene id: 8010:LOC105017806
uniprot id: A0A3P8XRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8010:adamts13
gene id: 8010:adamts13
uniprot id: A0A3P8YWS9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105014280
gene id: 8010:LOC105014280
uniprot id: A0A3P8Y297
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8010:minpp1b
gene id: 8010:minpp1b
uniprot id: A0A3P8XE08
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8010:tbca
gene id: 8010:tbca
uniprot id: C1BWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

8010:pde9a
gene id: 8010:pde9a
uniprot id: A0A3P8YHW0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:nfybb
gene id: 8010:nfybb
uniprot id: A0A3P8XSG2
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8010:LOC105016928
gene id: 8010:LOC105016928
uniprot id: A0A3P8XER4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8010:arl6ip4
gene id: 8010:arl6ip4
uniprot id: A0A3P8YFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

8010:gstt1b
gene id: 8010:gstt1b
uniprot id: C1BZD9
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8010:LOC105013381
gene id: 8010:LOC105013381
uniprot id: A0A3P8Z1V7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105025816
gene id: 8010:LOC105025816
uniprot id: A0A3P8YH10
uniprot id: A0A3P8YI97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8010:LOC105007783
gene id: 8010:LOC105007783
uniprot id: A0A3P8XI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8010:palm1b
gene id: 8010:palm1b
uniprot id: A0A3P8ZML8
names: Similarity
messages: Belongs to the paralemmin family.

8010:LOC105018431
gene id: 8010:LOC105018431
uniprot id: A0A3P8YY57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

8010:LOC105029791
gene id: 8010:LOC105029791
uniprot id: A0A3P8Z5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

8010:bpnt2
gene id: 8010:bpnt2
uniprot id: A0A3P8YX56
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8010:LOC105019908
gene id: 8010:LOC105019908
uniprot id: A0A3P8ZVK0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

8010:sema3e
gene id: 8010:sema3e
uniprot id: A0A3P9AH21
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:myf6
gene id: 8010:myf6
uniprot id: A0A3P8X8U9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8010:rad52
gene id: 8010:rad52
uniprot id: A0A3P9AP92
names: Similarity
messages: Belongs to the RAD52 family.

8010:tes
gene id: 8010:tes
uniprot id: A0A3P8Y5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

8010:snx5
gene id: 8010:snx5
uniprot id: A0A3P9A045
uniprot id: A0A6Q2X3Q4
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8010:LOC105007265
gene id: 8010:LOC105007265
uniprot id: A0A3P8XPM3
names: Similarity
messages: Belongs to the GAB family.

8010:gdap1
gene id: 8010:gdap1
uniprot id: A0A3P8XQ22
names: Similarity
messages: Belongs to the GST superfamily.

8010:rxfp3.2a
gene id: 8010:rxfp3.2a
uniprot id: A0A3P8XS15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105013293
gene id: 8010:LOC105013293
uniprot id: A0A3P9A410
names: Similarity
messages: Belongs to the DNase I family.

8010:sptlc2b
gene id: 8010:sptlc2b
uniprot id: A0A3P8XNZ5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8010:casp3a
gene id: 8010:casp3a
uniprot id: A0A6Q2YWF3
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:spx
gene id: 8010:spx
uniprot id: A0A3P8Y641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

8010:zmp:0000000951
gene id: 8010:zmp:0000000951
uniprot id: A0A3P8Z4G9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8010:zgc:66447
gene id: 8010:zgc:66447
uniprot id: A0A3P8ZIP5
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8010:usp3
gene id: 8010:usp3
uniprot id: A0A3P8ZF75
uniprot id: A0A3P8ZFD2
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:pcnp
gene id: 8010:pcnp
uniprot id: A0A3P8Y5D9
uniprot id: A0A3P8Y785
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

8010:vax1
gene id: 8010:vax1
uniprot id: A0A3P8YDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

8010:mpv17
gene id: 8010:mpv17
uniprot id: A0A3P9AQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8010:pou3f2a
gene id: 8010:pou3f2a
uniprot id: A0A3P8ZJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8010:tfdp1a
gene id: 8010:tfdp1a
uniprot id: A0A3P8YYZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:mafba
gene id: 8010:mafba
uniprot id: A0A3P8XBH0
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8010:map2k2b
gene id: 8010:map2k2b
uniprot id: A0A3P8ZQ23
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105018053
gene id: 8010:LOC105018053
uniprot id: A0A3P8ZM30
uniprot id: A0A3P8ZMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8010:oprk1
gene id: 8010:oprk1
uniprot id: A0A6Q2XXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:uts1
gene id: 8010:uts1
uniprot id: A0A6Q2Z1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8010:celsr1a
gene id: 8010:celsr1a
uniprot id: A0A3P8XWC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

8010:LOC105010711
gene id: 8010:LOC105010711
uniprot id: A0A3P8YS38
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8010:pex5
gene id: 8010:pex5
uniprot id: A0A3P8YUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

8010:LOC105023779
gene id: 8010:LOC105023779
uniprot id: A0A3P8YBY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8010:LOC105017536
gene id: 8010:LOC105017536
uniprot id: A0A3P8Y5S1
uniprot id: A0A3P8Y5V2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8010:LOC105019388
gene id: 8010:LOC105019388
uniprot id: A0A3P8XQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

8010:asah1b
gene id: 8010:asah1b
uniprot id: A0A3P9AK58
names: Similarity
messages: Belongs to the acid ceramidase family.

8010:p2rx3b
gene id: 8010:p2rx3b
uniprot id: A0A3P9AGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8010:jpt1a
gene id: 8010:jpt1a
uniprot id: A0A3P8XL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8010:tsn
gene id: 8010:tsn
uniprot id: A0A3P8XST7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

8010:LOC105028584
gene id: 8010:LOC105028584
uniprot id: A0A3P9AFZ4
names: Similarity
messages: Belongs to the MHC class I family.

8010:gucy1a2
gene id: 8010:gucy1a2
uniprot id: A0A3P8Y555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8010:LOC105022945
gene id: 8010:LOC105022945
uniprot id: A0A3P8YSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8010:eva1c
gene id: 8010:eva1c
uniprot id: A0A3P8XXR3
names: Similarity
messages: Belongs to the EVA1 family.

8010:LOC105009756
gene id: 8010:LOC105009756
uniprot id: A0A3P8YE00
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:ccna2
gene id: 8010:ccna2
uniprot id: A0A3P8X9Y5
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

8010:uhrf1
gene id: 8010:uhrf1
uniprot id: A0A3P9A3R2
names: Subcellular Location Annotation
messages: Nucleus

8010:cnih4
gene id: 8010:cnih4
uniprot id: C1BWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8010:dcps
gene id: 8010:dcps
uniprot id: A0A3P8YXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

8010:LOC105025750
gene id: 8010:LOC105025750
uniprot id: A0A3P8XVW6
uniprot id: A0A3P8ZTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

8010:xrn1
gene id: 8010:xrn1
uniprot id: A0A3P8ZKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

8010:yipf2
gene id: 8010:yipf2
uniprot id: A0A3P9ANZ5
uniprot id: C1BYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8010:ptgesl
gene id: 8010:ptgesl
uniprot id: A0A3P8X7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

8010:wnt2
gene id: 8010:wnt2
uniprot id: A0A3P9A069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:upp1
gene id: 8010:upp1
uniprot id: A0A6Q2Y3W7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8010:LOC105020060
gene id: 8010:LOC105020060
uniprot id: A0A3P9AQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8010:trappc4
gene id: 8010:trappc4
uniprot id: C1BY72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

8010:podxl
gene id: 8010:podxl
uniprot id: A0A3P8XI46
uniprot id: A0A3P8ZJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

8010:LOC105029903
gene id: 8010:LOC105029903
uniprot id: A0A3P8ZGX3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8010:LOC105015675
gene id: 8010:LOC105015675
uniprot id: A0A3P8XJD3
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:adora2ab
gene id: 8010:adora2ab
uniprot id: A0A3P8ZTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8010:LOC105015564
gene id: 8010:LOC105015564
uniprot id: A0A3P8Y2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105022372
gene id: 8010:LOC105022372
uniprot id: A0A3P9AIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

8010:LOC105016481
gene id: 8010:LOC105016481
uniprot id: A0A3P8XFH3
uniprot id: A0A3P8ZGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

8010:osgep
gene id: 8010:osgep
uniprot id: A0A3P9AJ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus

8010:LOC105031645
gene id: 8010:LOC105031645
uniprot id: A0A3P8YLW8
uniprot id: A0A3P9AAA7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:avp
gene id: 8010:avp
uniprot id: A0A3P8XBX4
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8010:cpne3
gene id: 8010:cpne3
uniprot id: A0A3P8XAS3
uniprot id: A0A3P8XAT8
uniprot id: A0A6Q2ZCL7
names: Similarity
messages: Belongs to the copine family.

8010:rbbp5
gene id: 8010:rbbp5
uniprot id: A0A3P8ZFJ1
uniprot id: A0A6Q2WYA7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105025314
gene id: 8010:LOC105025314
uniprot id: A0A3P9AHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8010:telo2
gene id: 8010:telo2
uniprot id: A0A3P8XW68
names: Similarity
messages: Belongs to the TEL2 family.

8010:tmem199
gene id: 8010:tmem199
uniprot id: A0A3P8Y1C3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:abhd3
gene id: 8010:abhd3
uniprot id: A0A3P8Z8C8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8010:ppt2b
gene id: 8010:ppt2b
uniprot id: A0A3P8ZP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

8010:eogt
gene id: 8010:eogt
uniprot id: A0A3P8XQD9
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

8010:cplane2
gene id: 8010:cplane2
uniprot id: A0A6Q2Z584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

8010:slitrk2
gene id: 8010:slitrk2
uniprot id: A0A3P9A245
names: Similarity
messages: Belongs to the SLITRK family.

8010:psmc2
gene id: 8010:psmc2
uniprot id: A0A3P9ALL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8010:otulina
gene id: 8010:otulina
uniprot id: A0A3P8XQB8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:sox21b
gene id: 8010:sox21b
uniprot id: A0A3P8XF66
names: Subcellular Location Annotation
messages: Nucleus

8010:mfsd1l
gene id: 8010:mfsd1l
uniprot id: A0A3P8ZS45
names: Subcellular Location Annotation
messages: Membrane

8010:eif4g1a
gene id: 8010:eif4g1a
uniprot id: A0A3P8XJP4
uniprot id: A0A3P8XMB7
uniprot id: A0A3P8XMT5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8010:LOC105015964
gene id: 8010:LOC105015964
uniprot id: A0A3P8YN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8010:cryz
gene id: 8010:cryz
uniprot id: A0A3P8Z5Y7
uniprot id: A0A3P8Z5Z8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8010:sppl3
gene id: 8010:sppl3
uniprot id: A0A3P8YUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8010:slc39a13
gene id: 8010:slc39a13
uniprot id: A0A3P8ZTA2
names: Subcellular Location Annotation
messages: Membrane

8010:coq4
gene id: 8010:coq4
uniprot id: A0A3P8Y7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

8010:LOC105011343
gene id: 8010:LOC105011343
uniprot id: A0A3P8YIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8010:nfe2l1b
gene id: 8010:nfe2l1b
uniprot id: A0A3P8ZRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:vopp1
gene id: 8010:vopp1
uniprot id: A0A6Q2YSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8010:fkbp6
gene id: 8010:fkbp6
uniprot id: A0A3P9A2T1
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

8010:LOC105020792
gene id: 8010:LOC105020792
uniprot id: A0A3P8XXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8010:txnl4a
gene id: 8010:txnl4a
uniprot id: C1BY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8010:ccnp
gene id: 8010:ccnp
uniprot id: A0A3P8ZZZ6
names: Similarity
messages: Belongs to the cyclin family.

8010:LOC105027272
gene id: 8010:LOC105027272
uniprot id: A0A3P8ZED1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8010:hpcal4
gene id: 8010:hpcal4
uniprot id: A0A3P9ACH3
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

8010:eftud2
gene id: 8010:eftud2
uniprot id: A0A3P9A9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

8010:dhx29
gene id: 8010:dhx29
uniprot id: A0A3P8XGQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

8010:gucy2c
gene id: 8010:gucy2c
uniprot id: A0A3P8XTV7
uniprot id: A0A3P8XV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8010:LOC105018281
gene id: 8010:LOC105018281
uniprot id: A0A3P8XXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:LOC105024994
gene id: 8010:LOC105024994
uniprot id: A0A6Q2X1F7
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8010:mastl
gene id: 8010:mastl
uniprot id: A0A3P8ZR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

8010:mmp15a
gene id: 8010:mmp15a
uniprot id: A0A3P9A411
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:vamp3
gene id: 8010:vamp3
uniprot id: A0A6Q2XN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8010:lsm7
gene id: 8010:lsm7
uniprot id: C1BZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

8010:kcnk6
gene id: 8010:kcnk6
uniprot id: A0A3P8Y811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:hyou1
gene id: 8010:hyou1
uniprot id: A0A3P8YJB7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8010:ppp5c
gene id: 8010:ppp5c
uniprot id: A0A3P9AIU8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

8010:arsk
gene id: 8010:arsk
uniprot id: A0A3P9ABF1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:LOC105025304
gene id: 8010:LOC105025304
uniprot id: A0A3P8YZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:atp6v0a1b
gene id: 8010:atp6v0a1b
uniprot id: A0A3P8XFH9
uniprot id: A0A3P8ZI51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8010:LOC105021807
gene id: 8010:LOC105021807
uniprot id: A0A3P8XQJ1
names: Similarity
messages: Belongs to the TEX28 family.

8010:lsm5
gene id: 8010:lsm5
uniprot id: A0A3P8ZPH6
uniprot id: C1BWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

8010:adgra3
gene id: 8010:adgra3
uniprot id: A0A3P8YML2
uniprot id: A0A3P8YNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

8010:LOC105019862
gene id: 8010:LOC105019862
uniprot id: A0A3P8XTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

8010:spinb
gene id: 8010:spinb
uniprot id: A0A3P8ZPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

8010:bmp1b
gene id: 8010:bmp1b
uniprot id: A0A6Q2YZE7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:sept8a
gene id: 8010:sept8a
uniprot id: A0A3P8Z8X3
uniprot id: A0A3P9ANK1
uniprot id: A0A6Q2XSP4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8010:tpst1
gene id: 8010:tpst1
uniprot id: A0A3P8XYA8
uniprot id: A0A3P8ZSA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8010:slc1a7b
gene id: 8010:slc1a7b
uniprot id: A0A3P9APX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:abcg4a
gene id: 8010:abcg4a
uniprot id: A0A3P8XV66
uniprot id: A0A3P8ZQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8010:eif5a
gene id: 8010:eif5a
uniprot id: C1BYX5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

8010:epha4b
gene id: 8010:epha4b
uniprot id: A0A3P8XL81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:anxa3a
gene id: 8010:anxa3a
uniprot id: A0A3P8YA23
uniprot id: A0A3P8YBG8
uniprot id: C1BZS7
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8010:cplx4c
gene id: 8010:cplx4c
uniprot id: A0A3P9A2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8010:sf3b1
gene id: 8010:sf3b1
uniprot id: A0A3P8ZLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

8010:sfmbt1
gene id: 8010:sfmbt1
uniprot id: A0A3P8XMH2
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105008693
gene id: 8010:LOC105008693
uniprot id: A0A3P9A0R9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8010:lhx3
gene id: 8010:lhx3
uniprot id: A0A3P8YGT8
uniprot id: A0A3P9A4I4
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105005787
gene id: 8010:LOC105005787
uniprot id: A0A3P8YV18
uniprot id: A0A3P9AFQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

8010:vti1a
gene id: 8010:vti1a
uniprot id: A0A3P8XMJ8
uniprot id: A0A3P8XMK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8010:nr2f6b
gene id: 8010:nr2f6b
uniprot id: A0A3P9AFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:aipl1
gene id: 8010:aipl1
uniprot id: A0A3P8ZN87
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be important in protein trafficking and/or protein folding and stabilization.
messages: Nucleus

8010:mrpl30
gene id: 8010:mrpl30
uniprot id: C1BWC5
uniprot id: C1BWY0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8010:c7b
gene id: 8010:c7b
uniprot id: A0A3P8Y6E4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105011433
gene id: 8010:LOC105011433
uniprot id: A0A3P8ZEK3
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105022369
gene id: 8010:LOC105022369
uniprot id: A0A3P8Z215
names: Subcellular Location Annotation
messages: Membrane

8010:dnajc16
gene id: 8010:dnajc16
uniprot id: A0A3P8ZI46
names: Subcellular Location Annotation
messages: Membrane

8010:ptpn11a
gene id: 8010:ptpn11a
uniprot id: A0A3P8X915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8010:dipk1c
gene id: 8010:dipk1c
uniprot id: A0A3P8XK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

8010:irf3
gene id: 8010:irf3
uniprot id: A0A3P8ZH68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:kat2a
gene id: 8010:kat2a
uniprot id: A0A3P9ACY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

8010:cstf3
gene id: 8010:cstf3
uniprot id: A0A3P9ANC3
names: Subcellular Location Annotation
messages: Nucleus

8010:plat
gene id: 8010:plat
uniprot id: A0A3P8XZY5
uniprot id: A0A3P8ZSK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:u2af2a
gene id: 8010:u2af2a
uniprot id: A0A3P8YH99
uniprot id: A0A3P8YJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8010:elovl6
gene id: 8010:elovl6
uniprot id: A0A6Q2YLG7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8010:hoxc13a
gene id: 8010:hoxc13a
uniprot id: A0A3P8XTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:nrn1lb
gene id: 8010:nrn1lb
uniprot id: A0A6Q2XYP3
names: Similarity
messages: Belongs to the neuritin family.

8010:rgs8
gene id: 8010:rgs8
uniprot id: A0A3P8XBV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

8010:sec13
gene id: 8010:sec13
uniprot id: A0A3P9ADL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

8010:fgf2
gene id: 8010:fgf2
uniprot id: A0A6Q2ZAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

8010:LOC105018205
gene id: 8010:LOC105018205
uniprot id: A0A3P9AI43
uniprot id: A0A3P9AI49
names: Similarity
messages: Belongs to the beta-catenin family.

8010:tbcb
gene id: 8010:tbcb
uniprot id: A0A3P9A3W4
uniprot id: C1BW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCB family.
messages: Cytoplasm

8010:galr1b
gene id: 8010:galr1b
uniprot id: A0A3P9AA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:rnd3a
gene id: 8010:rnd3a
uniprot id: A0A3P8YCT3
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8010:arid1aa
gene id: 8010:arid1aa
uniprot id: A0A3P9AKT8
names: Subcellular Location Annotation
messages: Nucleus

8010:tspan31
gene id: 8010:tspan31
uniprot id: A0A3P8ZMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:lig1
gene id: 8010:lig1
uniprot id: A0A3P8ZYX5
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

8010:hmx4
gene id: 8010:hmx4
uniprot id: A0A3P8XVC2
names: Subcellular Location Annotation
messages: Nucleus

8010:dpagt1
gene id: 8010:dpagt1
uniprot id: A0A3P8ZQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:hoxc1a
gene id: 8010:hoxc1a
uniprot id: A0A3P8XPW8
names: Subcellular Location Annotation
messages: Nucleus

8010:uckl1b
gene id: 8010:uckl1b
uniprot id: A0A3P8ZCI2
names: Similarity
messages: Belongs to the uridine kinase family.

8010:adck5
gene id: 8010:adck5
uniprot id: A0A3P8Y5W7
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8010:chaf1b
gene id: 8010:chaf1b
uniprot id: A0A3P8ZJ99
names: Subcellular Location Annotation
messages: Nucleus

8010:zgc:92907
gene id: 8010:zgc:92907
uniprot id: A0A6Q2Z530
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

8010:tlr9
gene id: 8010:tlr9
uniprot id: A0A3P8Y0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:LOC105029403
gene id: 8010:LOC105029403
uniprot id: A0A3P8XUI7
names: Subcellular Location Annotation
messages: Nucleus

8010:ube4b
gene id: 8010:ube4b
uniprot id: A0A3P8YC20
uniprot id: A0A3P9A179
uniprot id: A0A6Q2XGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8010:LOC105013819
gene id: 8010:LOC105013819
uniprot id: A0A3P8ZNF8
uniprot id: A0A6Q2ZKE6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:itga3b
gene id: 8010:itga3b
uniprot id: A0A3P8ZYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:sgsm1a
gene id: 8010:sgsm1a
uniprot id: A0A3P8XCQ6
names: Similarity
messages: Belongs to the RUTBC family.

8010:sema3b
gene id: 8010:sema3b
uniprot id: A0A3P8ZZ84
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cacng6b
gene id: 8010:cacng6b
uniprot id: A0A3P9A751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

8010:LOC105022430
gene id: 8010:LOC105022430
uniprot id: A0A3P8YS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:si:ch73-63e15.2
gene id: 8010:si:ch73-63e15.2
uniprot id: A0A3P8YXF3
uniprot id: A0A3P9AFX5
uniprot id: A0A3P9AH77
names: Similarity
messages: Belongs to the SBNO family.

8010:il17c
gene id: 8010:il17c
uniprot id: A0A3P8YE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8010:LOC105026424
gene id: 8010:LOC105026424
uniprot id: C1BZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:cdt1
gene id: 8010:cdt1
uniprot id: A0A3P8YSM1
names: Similarity
messages: Belongs to the Cdt1 family.

8010:vps37a
gene id: 8010:vps37a
uniprot id: A0A3P9AB53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8010:gde1
gene id: 8010:gde1
uniprot id: A0A3P8Z4H1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:mstna
gene id: 8010:mstna
uniprot id: A0A3P8YK15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8010:fgf14
gene id: 8010:fgf14
uniprot id: A0A3P8ZWD6
uniprot id: A0A3P8ZXJ2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8010:LOC105023172
gene id: 8010:LOC105023172
uniprot id: A0A6Q2XD08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8010:cntf
gene id: 8010:cntf
uniprot id: A0A3P8ZTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8010:ddr1
gene id: 8010:ddr1
uniprot id: A0A3P8XL72
uniprot id: A0A3P8ZM03
names: Subcellular Location Annotation
messages: Membrane

8010:rpl14
gene id: 8010:rpl14
uniprot id: A0A3P9APR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

8010:inpp5d
gene id: 8010:inpp5d
uniprot id: A0A3P8XSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8010:LOC105010660
gene id: 8010:LOC105010660
uniprot id: A0A3P8XR25
names: Similarity
messages: Belongs to the dickkopf family.

8010:brf1b
gene id: 8010:brf1b
uniprot id: A0A3P8XPA5
names: Similarity
messages: Belongs to the TFIIB family.

8010:irf2bp1
gene id: 8010:irf2bp1
uniprot id: A0A3P8Y7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8010:masp1
gene id: 8010:masp1
uniprot id: A0A3P8ZB87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:rab38a
gene id: 8010:rab38a
uniprot id: A0A3P8ZXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8010:LOC105007753
gene id: 8010:LOC105007753
uniprot id: A0A3P8Y0S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8010:cacng2a
gene id: 8010:cacng2a
uniprot id: A0A3P8YU25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8010:sbf2
gene id: 8010:sbf2
uniprot id: A0A6Q2YP89
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8010:eloa
gene id: 8010:eloa
uniprot id: A0A3P8Z6Q6
names: Subcellular Location Annotation
messages: Nucleus

8010:pgm2l1
gene id: 8010:pgm2l1
uniprot id: A0A3P8YLI0
uniprot id: A0A6Q2WSV0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8010:lmna
gene id: 8010:lmna
uniprot id: A0A3P8Y4N9
uniprot id: A0A3P8Y799
names: Similarity
messages: Belongs to the intermediate filament family.

8010:cry2
gene id: 8010:cry2
uniprot id: A0A3P8XZG0
uniprot id: A0A3P8ZU93
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8010:LOC105031585
gene id: 8010:LOC105031585
uniprot id: A0A3P8Z118
names: Similarity
messages: Belongs to the FAM110 family.

8010:auh
gene id: 8010:auh
uniprot id: A0A3P8YLY9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8010:wnt10b
gene id: 8010:wnt10b
uniprot id: A0A3P8XT64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:tlcd1
gene id: 8010:tlcd1
uniprot id: A0A3P8Z453
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105007400
gene id: 8010:LOC105007400
uniprot id: A0A3P8Y0L8
uniprot id: A0A3P8ZU58
uniprot id: A0A6Q2ZNI4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:golm2
gene id: 8010:golm2
uniprot id: A0A3P8YPJ2
uniprot id: A0A3P9AAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8010:myo3b
gene id: 8010:myo3b
uniprot id: A0A3P8Z114
uniprot id: A0A3P9AIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

8010:fam49a
gene id: 8010:fam49a
uniprot id: A0A3P8XZQ4
uniprot id: A0A3P8Y1F1
uniprot id: A0A6Q2XGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8010:homeza
gene id: 8010:homeza
uniprot id: A0A6Q2X0W3
names: Subcellular Location Annotation
messages: Nucleus

8010:mepce
gene id: 8010:mepce
uniprot id: A0A3P9ABR9
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8010:tlr1
gene id: 8010:tlr1
uniprot id: A0A3P9AD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:LOC105022382
gene id: 8010:LOC105022382
uniprot id: A0A3P8Z1H6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8010:LOC105030618
gene id: 8010:LOC105030618
uniprot id: A0A3P8YNJ7
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

8010:pgm3
gene id: 8010:pgm3
uniprot id: A0A3P8XIH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

8010:slc39a9
gene id: 8010:slc39a9
uniprot id: A0A3P9AJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

8010:LOC105019275
gene id: 8010:LOC105019275
uniprot id: A0A3P8ZT92
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8010:si:ch211-79m20.1
gene id: 8010:si:ch211-79m20.1
uniprot id: A0A3P8Z125
uniprot id: A0A3P8Z132
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8010:si:dkey-120c6.5
gene id: 8010:si:dkey-120c6.5
uniprot id: A0A6Q2YLJ3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:fgfr4
gene id: 8010:fgfr4
uniprot id: A0A3P8Y2X7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105027861
gene id: 8010:LOC105027861
uniprot id: A0A3P8XLE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8010:trarg1a
gene id: 8010:trarg1a
uniprot id: A0A3P8ZPG2
uniprot id: A0A3P8ZPI0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:LOC105012717
gene id: 8010:LOC105012717
uniprot id: A0A3P8YBQ2
names: Similarity
messages: Belongs to the MS4A family.

8010:LOC105025858
gene id: 8010:LOC105025858
uniprot id: A0A3P9AIR7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8010:akr1b1.2
gene id: 8010:akr1b1.2
uniprot id: A0A3P9A5S3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8010:kcnc1b
gene id: 8010:kcnc1b
uniprot id: A0A3P8Z0P1
uniprot id: A0A3P9AI88
names: Subcellular Location Annotation
messages: Membrane

8010:gpr143
gene id: 8010:gpr143
uniprot id: A0A3P8ZIP6
uniprot id: A0A6Q2ZGI1
names: Subcellular Location Annotation
messages: Membrane

8010:nptx1l
gene id: 8010:nptx1l
uniprot id: A0A3P9A873
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:npm1a
gene id: 8010:npm1a
uniprot id: A0A3P8YBY9
names: Similarity
messages: Belongs to the nucleoplasmin family.

8010:LOC105010799
gene id: 8010:LOC105010799
uniprot id: A0A3P8XQZ0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8010:LOC109616089
gene id: 8010:LOC109616089
uniprot id: A0A3P9AKL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8010:hs6st1b
gene id: 8010:hs6st1b
uniprot id: A0A3P8YM35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8010:sh3rf2
gene id: 8010:sh3rf2
uniprot id: A0A3P8Z903
names: Similarity
messages: Belongs to the SH3RF family.

8010:marcksl1a
gene id: 8010:marcksl1a
uniprot id: A0A3P8XCC3
names: Similarity
messages: Belongs to the MARCKS family.

8010:LOC105030519
gene id: 8010:LOC105030519
uniprot id: A0A3P8Y613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:irf4a
gene id: 8010:irf4a
uniprot id: A0A3P8YU54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105014920
gene id: 8010:LOC105014920
uniprot id: A0A3P8Z123
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:peli2
gene id: 8010:peli2
uniprot id: A0A3P8XT91
names: Similarity
messages: Belongs to the pellino family.

8010:ip6k1
gene id: 8010:ip6k1
uniprot id: A0A3P8YR80
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:LOC105016692
gene id: 8010:LOC105016692
uniprot id: A0A3P8YI53
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

8010:rem1
gene id: 8010:rem1
uniprot id: A0A3P8Z5X8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8010:meis2a
gene id: 8010:meis2a
uniprot id: A0A3P8ZM19
uniprot id: A0A3P8ZM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:LOC105015777
gene id: 8010:LOC105015777
uniprot id: A0A3P8X9I2
uniprot id: A0A3P8ZEK7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105020246
gene id: 8010:LOC105020246
uniprot id: A0A3P8XD69
uniprot id: A0A6Q2ZBT1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8010:snrpe
gene id: 8010:snrpe
uniprot id: C1BXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8010:spic
gene id: 8010:spic
uniprot id: A0A3P8ZFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:LOC105011087
gene id: 8010:LOC105011087
uniprot id: A0A3P8Y7X6
uniprot id: A0A6Q2Z1R6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8010:irf6
gene id: 8010:irf6
uniprot id: A0A3P9A4Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105006748
gene id: 8010:LOC105006748
uniprot id: A0A3P8ZQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8010:gucy1b1
gene id: 8010:gucy1b1
uniprot id: A0A3P8XFG8
uniprot id: A0A3P8XI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8010:jagn1b
gene id: 8010:jagn1b
uniprot id: A0A3P8Z7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:cwf19l1
gene id: 8010:cwf19l1
uniprot id: A0A3P8Y0H5
names: Similarity
messages: Belongs to the CWF19 family.

8010:kcng1
gene id: 8010:kcng1
uniprot id: A0A3P8ZJY8
names: Subcellular Location Annotation
messages: Membrane

8010:tfcp2
gene id: 8010:tfcp2
uniprot id: A0A3P8XGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8010:LOC105022412
gene id: 8010:LOC105022412
uniprot id: A0A3P8YG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8010:ptgdsa
gene id: 8010:ptgdsa
uniprot id: A0A3P8XNH9
uniprot id: A0A6Q2Y7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Nucleus

8010:LOC105013569
gene id: 8010:LOC105013569
uniprot id: A0A3P8ZJG0
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8010:trim45
gene id: 8010:trim45
uniprot id: A0A3P8XJ99
uniprot id: A0A3P8ZKT4
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8010:ap3m2
gene id: 8010:ap3m2
uniprot id: A0A3P8ZL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

8010:si:ch211-149k23.9
gene id: 8010:si:ch211-149k23.9
uniprot id: A0A3P8YHR8
uniprot id: A0A3P8YHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8010:LOC105021565
gene id: 8010:LOC105021565
uniprot id: A0A3P8YC49
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:acot8
gene id: 8010:acot8
uniprot id: A0A6Q2X694
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8010:gphb5
gene id: 8010:gphb5
uniprot id: A0A3P8Y6R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8010:tgs1
gene id: 8010:tgs1
uniprot id: A0A3P8Y882
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

8010:acvr1l
gene id: 8010:acvr1l
uniprot id: A0A3P9ANE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:sv2ba
gene id: 8010:sv2ba
uniprot id: A0A3P9A7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8010:prkd1
gene id: 8010:prkd1
uniprot id: A0A3P8ZGG4
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8010:rab33a
gene id: 8010:rab33a
uniprot id: A0A3P9A0B3
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8010:fbxo25
gene id: 8010:fbxo25
uniprot id: A0A3P9A339
uniprot id: A0A3P9A4A7
names: Subcellular Location Annotation
messages: Nucleus

8010:lamtor5
gene id: 8010:lamtor5
uniprot id: C1BW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

8010:phax
gene id: 8010:phax
uniprot id: A0A3P8YRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

8010:LOC105021743
gene id: 8010:LOC105021743
uniprot id: A0A3P8YQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8010:lmf2b
gene id: 8010:lmf2b
uniprot id: A0A3P8YWA2
uniprot id: A0A3P8YXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

8010:LOC105029515
gene id: 8010:LOC105029515
uniprot id: A0A3P8Y7M3
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105019928
gene id: 8010:LOC105019928
uniprot id: A0A3P8Y4U7
uniprot id: A0A3P8Y6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8010:naa10
gene id: 8010:naa10
uniprot id: C1BZD2
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

8010:adck2
gene id: 8010:adck2
uniprot id: A0A3P8XTD7
uniprot id: A0A3P8XWJ4
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8010:rgs2
gene id: 8010:rgs2
uniprot id: A0A3P8XB98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

8010:enpep
gene id: 8010:enpep
uniprot id: A0A3P8YBP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

8010:tmtc3
gene id: 8010:tmtc3
uniprot id: A0A3P8Y4D7
uniprot id: A0A3P8ZYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8010:tmem231
gene id: 8010:tmem231
uniprot id: A0A3P9A030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

8010:txnrd3
gene id: 8010:txnrd3
uniprot id: A0A3P8Y689
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

8010:pax1b
gene id: 8010:pax1b
uniprot id: A0A3P8YEZ9
uniprot id: A0A3P9A5I9
names: Subcellular Location Annotation
messages: Nucleus

8010:ano10a
gene id: 8010:ano10a
uniprot id: A0A3P8XED7
uniprot id: A0A3P8ZHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8010:lsm3
gene id: 8010:lsm3
uniprot id: C1BZD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8010:gpm6ab
gene id: 8010:gpm6ab
uniprot id: A0A3P8YR49
uniprot id: A0A3P9ACR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8010:LOC105031173
gene id: 8010:LOC105031173
uniprot id: A0A3P8YNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8010:ogfod1
gene id: 8010:ogfod1
uniprot id: A0A3P8ZYV7
names: Similarity
messages: Belongs to the TPA1 family.

8010:adamts2
gene id: 8010:adamts2
uniprot id: A0A3P9APH2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:dlx1a
gene id: 8010:dlx1a
uniprot id: A0A3P9AJY3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105011369
gene id: 8010:LOC105011369
uniprot id: A0A3P8XFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8010:LOC105022536
gene id: 8010:LOC105022536
uniprot id: A0A3P8YGZ8
uniprot id: A0A6Q2XL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8010:LOC105020261
gene id: 8010:LOC105020261
uniprot id: A0A6Q2Z3D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:brpf3b
gene id: 8010:brpf3b
uniprot id: A0A3P8ZJN8
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105028801
gene id: 8010:LOC105028801
uniprot id: A0A3P8Z3R5
uniprot id: A0A3P8Z3T5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

8010:LOC105021745
gene id: 8010:LOC105021745
uniprot id: A0A3P8YQU4
uniprot id: A0A3P8YQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

8010:slc19a3a
gene id: 8010:slc19a3a
uniprot id: A0A3P8YTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8010:plrg1
gene id: 8010:plrg1
uniprot id: A0A3P8YZB9
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

8010:LOC105025973
gene id: 8010:LOC105025973
uniprot id: A0A3P8Z8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:ppm1nb
gene id: 8010:ppm1nb
uniprot id: A0A3P8ZS92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8010:LOC105018413
gene id: 8010:LOC105018413
uniprot id: A0A3P8XEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8010:LOC105010937
gene id: 8010:LOC105010937
uniprot id: C1BZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

8010:si:dkey-72l14.3
gene id: 8010:si:dkey-72l14.3
uniprot id: A0A3P8ZXK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8010:hnf1ba
gene id: 8010:hnf1ba
uniprot id: A0A3P8Z1Z7
uniprot id: A0A3P9AK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8010:eif6
gene id: 8010:eif6
uniprot id: A0A6Q2X928
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

8010:ebpl
gene id: 8010:ebpl
uniprot id: A0A3P8XL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:cxcr4b
gene id: 8010:cxcr4b
uniprot id: A0A3P8YEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8010:kcnk5a
gene id: 8010:kcnk5a
uniprot id: A0A3P8Y8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:barhl1b
gene id: 8010:barhl1b
uniprot id: A0A3P8YKX7
names: Subcellular Location Annotation
messages: Nucleus

8010:ska2
gene id: 8010:ska2
uniprot id: A0A3P9A0C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

8010:dmgdh
gene id: 8010:dmgdh
uniprot id: A0A3P8ZLL3
names: Similarity
messages: Belongs to the GcvT family.

8010:LOC105013723
gene id: 8010:LOC105013723
uniprot id: A0A3P8YV27
uniprot id: A0A3P8YW96
names: Similarity
messages: Belongs to the PPP4R2 family.

8010:dydc2
gene id: 8010:dydc2
uniprot id: A0A3P8ZU82
names: Similarity
messages: Belongs to the dpy-30 family.

8010:LOC105024893
gene id: 8010:LOC105024893
uniprot id: A0A3P8Y0M2
uniprot id: A0A3P8Y0P2
uniprot id: A0A3P8Y0Q5
names: Subcellular Location Annotation
messages: Membrane

8010:psma1
gene id: 8010:psma1
uniprot id: C1BW00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:htr2cl1
gene id: 8010:htr2cl1
uniprot id: A0A6Q2Z7A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

8010:slc6a6a
gene id: 8010:slc6a6a
uniprot id: A0A3P8ZB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

8010:cfap126
gene id: 8010:cfap126
uniprot id: A0A3P9AH87
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

8010:LOC105014034
gene id: 8010:LOC105014034
uniprot id: A0A3P9AMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:LOC105029954
gene id: 8010:LOC105029954
uniprot id: A0A6Q2WSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

8010:mms22l
gene id: 8010:mms22l
uniprot id: A0A3P8Z3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

8010:mettl11b
gene id: 8010:mettl11b
uniprot id: A0A3P8YZV0
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8010:timp2b
gene id: 8010:timp2b
uniprot id: A0A3P8YDM1
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8010:LOC105027114
gene id: 8010:LOC105027114
uniprot id: A0A3P8XAF1
uniprot id: A0A3P8XAF3
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:fbln5
gene id: 8010:fbln5
uniprot id: A0A3P8Z0T6
uniprot id: A0A3P9AJ99
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105008641
gene id: 8010:LOC105008641
uniprot id: A0A3P8Z7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105021040
gene id: 8010:LOC105021040
uniprot id: A0A3P8YPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8010:tnfsf11
gene id: 8010:tnfsf11
uniprot id: A0A3P8XVB2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8010:itgb5
gene id: 8010:itgb5
uniprot id: A0A3P8XMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8010:slc34a2b
gene id: 8010:slc34a2b
uniprot id: A0A3P8XNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

8010:gpr182
gene id: 8010:gpr182
uniprot id: A0A3P8XSG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:uba2
gene id: 8010:uba2
uniprot id: A0A3P8Y107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

8010:ccnh
gene id: 8010:ccnh
uniprot id: A0A3P9A7T2
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

8010:olfml3b
gene id: 8010:olfml3b
uniprot id: A0A3P8Z2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Secreted

8010:parvab
gene id: 8010:parvab
uniprot id: A0A3P9A623
uniprot id: A0A6Q2WS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8010:si:dkeyp-67f1.2
gene id: 8010:si:dkeyp-67f1.2
uniprot id: A0A3P8XDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8010:stx2b
gene id: 8010:stx2b
uniprot id: A0A3P8YY99
uniprot id: A0A6Q2WQU0
uniprot id: A0A6Q2XIX6
names: Similarity
messages: Belongs to the syntaxin family.

8010:topaz1
gene id: 8010:topaz1
uniprot id: A0A3P9AQ09
names: Function
names: Subcellular Location Annotation
messages: Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
messages: cytosol

8010:fam219ab
gene id: 8010:fam219ab
uniprot id: A0A3P8XAJ2
names: Similarity
messages: Belongs to the FAM219 family.

8010:LOC105011030
gene id: 8010:LOC105011030
uniprot id: A0A3P8YXT5
uniprot id: A0A3P9AH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8010:gpd2
gene id: 8010:gpd2
uniprot id: A0A3P8X7G7
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

8010:prorp
gene id: 8010:prorp
uniprot id: A0A3P8XIR8
names: Similarity
messages: Belongs to the PPR family. P subfamily.

8010:klhl3
gene id: 8010:klhl3
uniprot id: A0A3P9A2R9
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

8010:tk2
gene id: 8010:tk2
uniprot id: A0A3P8YTK1
names: Similarity
messages: Belongs to the DCK/DGK family.

8010:LOC105014584
gene id: 8010:LOC105014584
uniprot id: A0A3P9AH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8010:nt5dc3
gene id: 8010:nt5dc3
uniprot id: A0A3P8XRF3
uniprot id: A0A6Q2XNU1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8010:camk1db
gene id: 8010:camk1db
uniprot id: A0A3P8ZP81
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105028783
gene id: 8010:LOC105028783
uniprot id: A0A3P8ZMC1
uniprot id: A0A6Q2XXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8010:nell2a
gene id: 8010:nell2a
uniprot id: A0A6Q2XEK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:echdc1
gene id: 8010:echdc1
uniprot id: A0A3P8ZG02
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8010:LOC105023692
gene id: 8010:LOC105023692
uniprot id: A0A3P8YDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8010:taf13
gene id: 8010:taf13
uniprot id: C1BXV8
names: Subcellular Location Annotation
messages: Nucleus

8010:fam120b
gene id: 8010:fam120b
uniprot id: A0A3P8YEJ1
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8010:zgc:172145
gene id: 8010:zgc:172145
uniprot id: A0A3P8XMI0
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:dpysl2a
gene id: 8010:dpysl2a
uniprot id: A0A3P9ACI9
uniprot id: A0A6Q2WVQ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8010:chrna6
gene id: 8010:chrna6
uniprot id: A0A3P8ZYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:chrna11
gene id: 8010:chrna11
uniprot id: A0A3P8XS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:nubp2
gene id: 8010:nubp2
uniprot id: C1BW41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8010:limk1a
gene id: 8010:limk1a
uniprot id: A0A3P8XRY5
uniprot id: A0A3P8XTZ8
uniprot id: A0A3P8ZQ08
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8010:tram2
gene id: 8010:tram2
uniprot id: A0A3P9A7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8010:nek8
gene id: 8010:nek8
uniprot id: A0A3P8Z335
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8010:agbl4
gene id: 8010:agbl4
uniprot id: A0A3P8ZQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

8010:ribc2
gene id: 8010:ribc2
uniprot id: A0A3P9ABZ2
names: Similarity
messages: Belongs to the RIB43A family.

8010:ido1
gene id: 8010:ido1
uniprot id: A0A3P8YP32
uniprot id: A0A6Q2XK12
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8010:inpp4ab
gene id: 8010:inpp4ab
uniprot id: A0A3P8ZKQ7
uniprot id: A0A6Q2YQ96
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8010:LOC105028341
gene id: 8010:LOC105028341
uniprot id: A0A3P8ZWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8010:ncln
gene id: 8010:ncln
uniprot id: A0A3P9ANV7
names: Similarity
messages: Belongs to the nicastrin family.

8010:slc35b3
gene id: 8010:slc35b3
uniprot id: A0A3P8YYH0
uniprot id: A0A3P8YYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8010:pim2
gene id: 8010:pim2
uniprot id: A0A3P8XFW9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8010:itpkcb
gene id: 8010:itpkcb
uniprot id: A0A3P9A4I8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8010:mcu
gene id: 8010:mcu
uniprot id: A0A3P9A6H7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

8010:LOC105020007
gene id: 8010:LOC105020007
uniprot id: A0A3P8Z2V2
names: Subcellular Location Annotation
messages: Cell membrane
messages: invadopodium membrane
messages: lamellipodium membrane

8010:nkx2.4a
gene id: 8010:nkx2.4a
uniprot id: A0A3P8XA39
names: Subcellular Location Annotation
messages: Nucleus

8010:nagpa
gene id: 8010:nagpa
uniprot id: A0A3P8XX13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cartl
gene id: 8010:cartl
uniprot id: A0A3P8XA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8010:LOC105015380
gene id: 8010:LOC105015380
uniprot id: A0A3P9AH79
names: Similarity
messages: Belongs to the fl(2)d family.

8010:btk
gene id: 8010:btk
uniprot id: A0A3P8YIM7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:atp2a2a
gene id: 8010:atp2a2a
uniprot id: A0A3P8X788
uniprot id: A0A3P8ZBM4
uniprot id: A0A3P8ZCP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8010:slc46a1
gene id: 8010:slc46a1
uniprot id: A0A3P8ZP55
names: Subcellular Location Annotation
messages: Membrane

8010:opn8b
gene id: 8010:opn8b
uniprot id: A0A3P8YDK6
names: Subcellular Location Annotation
messages: Membrane

8010:tymp
gene id: 8010:tymp
uniprot id: A0A3P8ZUG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

8010:zgc:66484
gene id: 8010:zgc:66484
uniprot id: A0A3P9A1P8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8010:atp6ap1b
gene id: 8010:atp6ap1b
uniprot id: A0A3P8XKP2
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8010:gipc1
gene id: 8010:gipc1
uniprot id: A0A3P9ALL7
names: Similarity
messages: Belongs to the GIPC family.

8010:LOC105013108
gene id: 8010:LOC105013108
uniprot id: A0A3P8Y9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:cnrip1a
gene id: 8010:cnrip1a
uniprot id: A0A6Q2XXQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8010:zfhx3
gene id: 8010:zfhx3
uniprot id: A0A3P8YCD8
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105029556
gene id: 8010:LOC105029556
uniprot id: A0A3P8Y5V4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:LOC105025528
gene id: 8010:LOC105025528
uniprot id: C1BXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

8010:LOC105013695
gene id: 8010:LOC105013695
uniprot id: A0A3P8Z1D6
uniprot id: A0A3P8Z1L9
uniprot id: A0A3P8Z359
uniprot id: A0A3P9AIN4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:galnt2
gene id: 8010:galnt2
uniprot id: A0A3P8YD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:farsa
gene id: 8010:farsa
uniprot id: A0A3P8XYU8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

8010:phkb
gene id: 8010:phkb
uniprot id: A0A3P8YT59
uniprot id: A0A3P9AD08
uniprot id: A0A3P9ADJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

8010:LOC105015836
gene id: 8010:LOC105015836
uniprot id: A0A3P8X879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8010:nt5c3a
gene id: 8010:nt5c3a
uniprot id: A0A3P8Y285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8010:wnt1
gene id: 8010:wnt1
uniprot id: A0A3P8XVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:ddr2l
gene id: 8010:ddr2l
uniprot id: A0A3P9AIY9
names: Subcellular Location Annotation
messages: Membrane

8010:fam49ba
gene id: 8010:fam49ba
uniprot id: A0A6Q2Y9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8010:slc37a1
gene id: 8010:slc37a1
uniprot id: A0A3P9A7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8010:s1pr5a
gene id: 8010:s1pr5a
uniprot id: A0A3P8ZTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:snrpb
gene id: 8010:snrpb
uniprot id: A0A3P9A479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

8010:flcn
gene id: 8010:flcn
uniprot id: A0A3P8YFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

8010:gdpd2
gene id: 8010:gdpd2
uniprot id: A0A3P8ZDL2
uniprot id: A0A3P8ZDL8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:decr2
gene id: 8010:decr2
uniprot id: A0A3P8XW86
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

8010:enpp2
gene id: 8010:enpp2
uniprot id: A0A3P9AMX2
uniprot id: A0A6Q2YAS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Secreted

8010:plaa
gene id: 8010:plaa
uniprot id: A0A3P8YG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

8010:LOC105027351
gene id: 8010:LOC105027351
uniprot id: A0A3P8YJX0
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105030868
gene id: 8010:LOC105030868
uniprot id: C1BWW7
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8010:ttc4
gene id: 8010:ttc4
uniprot id: A0A3P9AMI0
names: Similarity
messages: Belongs to the TTC4 family.

8010:gpam
gene id: 8010:gpam
uniprot id: A0A3P8XNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

8010:LOC105016946
gene id: 8010:LOC105016946
uniprot id: A0A3P9AJ74
uniprot id: A0A6Q2Y1U3
names: Similarity
messages: Belongs to the NRAMP family.

8010:pigp
gene id: 8010:pigp
uniprot id: C1BX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

8010:ncanb
gene id: 8010:ncanb
uniprot id: A0A3P8YWP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105026630
gene id: 8010:LOC105026630
uniprot id: A0A6Q2XS48
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:inaa
gene id: 8010:inaa
uniprot id: A0A3P8YG16
names: Similarity
messages: Belongs to the intermediate filament family.

8010:snx6
gene id: 8010:snx6
uniprot id: A0A6Q2YK49
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8010:psmb1
gene id: 8010:psmb1
uniprot id: C1BXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8010:ptp4a3b
gene id: 8010:ptp4a3b
uniprot id: A0A3P8Z135
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8010:rnf168
gene id: 8010:rnf168
uniprot id: A0A3P8YM64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

8010:slc6a1l
gene id: 8010:slc6a1l
uniprot id: A0A3P9AQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:pax8
gene id: 8010:pax8
uniprot id: A0A3P8Y824
uniprot id: A0A3P9A0C3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105023753
gene id: 8010:LOC105023753
uniprot id: A0A3P8YGQ8
names: Similarity
messages: Belongs to the peptidase A1 family.

8010:sgo1
gene id: 8010:sgo1
uniprot id: A0A3P8XLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

8010:dbx1a
gene id: 8010:dbx1a
uniprot id: A0A3P8ZBW6
names: Subcellular Location Annotation
messages: Nucleus

8010:sar1b
gene id: 8010:sar1b
uniprot id: C1BX10
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

8010:epha2b
gene id: 8010:epha2b
uniprot id: A0A3P8YJC5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:mul1b
gene id: 8010:mul1b
uniprot id: A0A3P8ZHA9
names: Subcellular Location Annotation
messages: Membrane

8010:utp18
gene id: 8010:utp18
uniprot id: A0A3P9A5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

8010:rhbdf1a
gene id: 8010:rhbdf1a
uniprot id: A0A3P8Z3T9
uniprot id: A0A3P9AJ30
uniprot id: A0A6Q2YCU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8010:pex12
gene id: 8010:pex12
uniprot id: A0A3P8Y717
uniprot id: A0A3P8ZZN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

8010:mtnr1c
gene id: 8010:mtnr1c
uniprot id: A0A3P8YTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8010:ptgs2b
gene id: 8010:ptgs2b
uniprot id: A0A3P9AGT2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

8010:cmpk
gene id: 8010:cmpk
uniprot id: C1BYB2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8010:plbd1
gene id: 8010:plbd1
uniprot id: A0A3P8ZQX5
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8010:parvg
gene id: 8010:parvg
uniprot id: A0A3P8XU82
uniprot id: A0A3P8XWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8010:vclb
gene id: 8010:vclb
uniprot id: A0A3P8Y3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

8010:LOC105023858
gene id: 8010:LOC105023858
uniprot id: A0A3P8ZXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105024911
gene id: 8010:LOC105024911
uniprot id: A0A3P8ZBI9
uniprot id: A0A6Q2WYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8010:itgb7
gene id: 8010:itgb7
uniprot id: A0A3P9A5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8010:ppip5k1a
gene id: 8010:ppip5k1a
uniprot id: A0A3P8XB29
uniprot id: A0A3P8ZEJ2
uniprot id: A0A3P8ZF66
uniprot id: A0A3P8ZF90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

8010:arid1b
gene id: 8010:arid1b
uniprot id: A0A3P8YCQ5
uniprot id: A0A3P8YCS6
names: Subcellular Location Annotation
messages: Nucleus

8010:alkal2b
gene id: 8010:alkal2b
uniprot id: A0A3P9AC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8010:LOC105016509
gene id: 8010:LOC105016509
uniprot id: A0A3P8ZGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8010:men1
gene id: 8010:men1
uniprot id: A0A3P9A1M7
names: Subcellular Location Annotation
messages: Nucleus

8010:rspo1
gene id: 8010:rspo1
uniprot id: A0A3P8YMC9
names: Similarity
messages: Belongs to the R-spondin family.

8010:mlst8
gene id: 8010:mlst8
uniprot id: C1BWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

8010:gpat3
gene id: 8010:gpat3
uniprot id: A0A3P8ZAI2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:lum
gene id: 8010:lum
uniprot id: A0A3P8X9Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

8010:egr1
gene id: 8010:egr1
uniprot id: A0A3P8YFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8010:LOC105031290
gene id: 8010:LOC105031290
uniprot id: A0A3P8YA92
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8010:gdf10a
gene id: 8010:gdf10a
uniprot id: A0A3P8XZG7
names: Similarity
messages: Belongs to the TGF-beta family.

8010:dbpa
gene id: 8010:dbpa
uniprot id: A0A6Q2YED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8010:asphd2
gene id: 8010:asphd2
uniprot id: A0A3P8Z7X1
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

8010:LOC105013784
gene id: 8010:LOC105013784
uniprot id: A0A3P9AKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

8010:osbpl1a
gene id: 8010:osbpl1a
uniprot id: A0A3P9A1F6
uniprot id: A0A3P9A2N9
names: Similarity
messages: Belongs to the OSBP family.

8010:slc35f6
gene id: 8010:slc35f6
uniprot id: A0A3P8YBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

8010:ttc19
gene id: 8010:ttc19
uniprot id: A0A6Q2WV09
names: Similarity
messages: Belongs to the TTC19 family.

8010:LOC105024543
gene id: 8010:LOC105024543
uniprot id: A0A3P8Y1Y7
names: Similarity
messages: Belongs to the EPS8 family.

8010:edem2
gene id: 8010:edem2
uniprot id: A0A3P8ZXL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8010:zer1
gene id: 8010:zer1
uniprot id: A0A3P9AHR2
names: Similarity
messages: Belongs to the zyg-11 family.

8010:ldlrad4a
gene id: 8010:ldlrad4a
uniprot id: A0A3P8YDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8010:rft1
gene id: 8010:rft1
uniprot id: A0A3P9A7Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

8010:gask1a
gene id: 8010:gask1a
uniprot id: A0A3P8ZP21
names: Similarity
messages: Belongs to the GASK family.

8010:LOC105029555
gene id: 8010:LOC105029555
uniprot id: A0A3P8ZYW4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8010:rps6kb1a
gene id: 8010:rps6kb1a
uniprot id: A0A3P9ALS0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8010:rpgrip1l
gene id: 8010:rpgrip1l
uniprot id: A0A3P9AB54
uniprot id: A0A3P9ABB2
names: Similarity
messages: Belongs to the RPGRIP1 family.

8010:bsk146
gene id: 8010:bsk146
uniprot id: A0A3P8Z115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

8010:mtfr1l
gene id: 8010:mtfr1l
uniprot id: A0A3P9A2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8010:LOC105009430
gene id: 8010:LOC105009430
uniprot id: A0A3P9AGU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:zgc:103625
gene id: 8010:zgc:103625
uniprot id: A0A3P8ZU37
names: Similarity
messages: Belongs to the UPF0585 family.

8010:exoc3l1
gene id: 8010:exoc3l1
uniprot id: A0A3P8Y4K0
uniprot id: A0A3P8Y4M8
names: Similarity
messages: Belongs to the SEC6 family.

8010:psmb7
gene id: 8010:psmb7
uniprot id: A0A3P8YTL7
uniprot id: C1BYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8010:rab38b
gene id: 8010:rab38b
uniprot id: A0A3P9AI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8010:LOC105016696
gene id: 8010:LOC105016696
uniprot id: C1BX50
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

8010:sv2a
gene id: 8010:sv2a
uniprot id: A0A3P9A009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8010:slc8a1b
gene id: 8010:slc8a1b
uniprot id: A0A3P8ZF51
uniprot id: A0A3P8ZF55
uniprot id: A0A3P8ZH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8010:bbs5
gene id: 8010:bbs5
uniprot id: A0A3P8YYM9
uniprot id: A0A6Q2XG34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8010:rab3ip
gene id: 8010:rab3ip
uniprot id: A0A3P8Y5U6
uniprot id: A0A3P8ZY27
names: Similarity
messages: Belongs to the SEC2 family.

8010:cacna1sa
gene id: 8010:cacna1sa
uniprot id: A0A3P8XR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

8010:snx21
gene id: 8010:snx21
uniprot id: A0A3P8Y416
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8010:LOC105017245
gene id: 8010:LOC105017245
uniprot id: A0A3P8ZQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8010:LOC105022386
gene id: 8010:LOC105022386
uniprot id: A0A3P8Z025
uniprot id: A0A3P8Z1K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:smarcad1b
gene id: 8010:smarcad1b
uniprot id: A0A3P8YV94
names: Subcellular Location Annotation
messages: Chromosome

8010:tnfsf10l3
gene id: 8010:tnfsf10l3
uniprot id: A0A3P8XJG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8010:cadm3
gene id: 8010:cadm3
uniprot id: A0A3P8Y8B1
uniprot id: A0A3P8ZYV6
names: Similarity
messages: Belongs to the nectin family.

8010:LOC105026094
gene id: 8010:LOC105026094
uniprot id: A0A6Q2Z926
uniprot id: A0A6Q2ZLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8010:tlx3b
gene id: 8010:tlx3b
uniprot id: A0A3P8YAL6
names: Subcellular Location Annotation
messages: Nucleus

8010:nop2
gene id: 8010:nop2
uniprot id: A0A3P8YNM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

8010:mrps12
gene id: 8010:mrps12
uniprot id: A0A6Q2Z781
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

8010:clp1
gene id: 8010:clp1
uniprot id: A0A3P8Z991
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

8010:pomgnt1
gene id: 8010:pomgnt1
uniprot id: A0A3P8Z186
uniprot id: A0A3P9AH94
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

8010:pex16
gene id: 8010:pex16
uniprot id: A0A3P9AGN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Peroxisome membrane

8010:LOC105008707
gene id: 8010:LOC105008707
uniprot id: A0A6Q2Z9W3
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

8010:LOC105006827
gene id: 8010:LOC105006827
uniprot id: A0A3P9AE54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

8010:LOC105018217
gene id: 8010:LOC105018217
uniprot id: A0A3P8YE27
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:usp13
gene id: 8010:usp13
uniprot id: A0A3P8XIJ4
uniprot id: A0A3P8ZHC9
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:smim12
gene id: 8010:smim12
uniprot id: A0A6Q2ZI14
names: Similarity
messages: Belongs to the SMIM12 family.

8010:tmem229b
gene id: 8010:tmem229b
uniprot id: A0A3P9AIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

8010:tbx3a
gene id: 8010:tbx3a
uniprot id: A0A3P8Y9D5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:cd247
gene id: 8010:cd247
uniprot id: A0A3P8Z9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

8010:LOC105009418
gene id: 8010:LOC105009418
uniprot id: A0A3P8YEQ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:phb2b
gene id: 8010:phb2b
uniprot id: A0A3P9AE39
uniprot id: A0A6Q2WVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8010:chchd4a
gene id: 8010:chchd4a
uniprot id: A0A3P8XPH2
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8010:fgf8b
gene id: 8010:fgf8b
uniprot id: A0A3P8XJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

8010:pax9
gene id: 8010:pax9
uniprot id: A0A3P9AJD0
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105022228
gene id: 8010:LOC105022228
uniprot id: A0A3P8Z9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

8010:arf4
gene id: 8010:arf4
uniprot id: A0A6Q2XBG0
uniprot id: C1BXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8010:LOC105031402
gene id: 8010:LOC105031402
uniprot id: A0A3P8Z0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8010:cpsf4
gene id: 8010:cpsf4
uniprot id: A0A3P8Y330
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8010:mmab
gene id: 8010:mmab
uniprot id: C1BXH0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

8010:ptger4a
gene id: 8010:ptger4a
uniprot id: A0A3P8X8L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8010:eif1axb
gene id: 8010:eif1axb
uniprot id: C1BXX4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

8010:dna2
gene id: 8010:dna2
uniprot id: A0A3P8YSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

8010:zdhhc4
gene id: 8010:zdhhc4
uniprot id: A0A3P9ADQ4
uniprot id: C1BWC4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:si:dkey-243k1.3
gene id: 8010:si:dkey-243k1.3
uniprot id: A0A3P9ADW2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8010:gdf6b
gene id: 8010:gdf6b
uniprot id: A0A3P8Y0N7
names: Similarity
messages: Belongs to the TGF-beta family.

8010:elovl4b
gene id: 8010:elovl4b
uniprot id: A0A3P8XIU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8010:ggt5b
gene id: 8010:ggt5b
uniprot id: A0A3P9AGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8010:slc2a15b
gene id: 8010:slc2a15b
uniprot id: A0A3P8XFC5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:vwc2l
gene id: 8010:vwc2l
uniprot id: A0A3P8ZQL4
uniprot id: A0A3P8ZRX8
names: Subcellular Location Annotation
messages: Synapse

8010:actr5
gene id: 8010:actr5
uniprot id: A0A3P8YB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family. ARP5 subfamily.
messages: Nucleus

8010:sf3a1
gene id: 8010:sf3a1
uniprot id: A0A3P9ALP9
names: Subcellular Location Annotation
messages: Nucleus

8010:nifk
gene id: 8010:nifk
uniprot id: A0A3P8XQZ9
names: Subcellular Location Annotation
messages: nucleolus

8010:khdc4
gene id: 8010:khdc4
uniprot id: A0A3P8YC56
names: Similarity
messages: Belongs to the KHDC4 family.

8010:slc7a3b
gene id: 8010:slc7a3b
uniprot id: A0A3P8X9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8010:paqr8
gene id: 8010:paqr8
uniprot id: A0A3P8XWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:pmpca
gene id: 8010:pmpca
uniprot id: A0A3P8ZDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix
messages: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

8010:LOC105007988
gene id: 8010:LOC105007988
uniprot id: A0A3P8XP75
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:vat1l
gene id: 8010:vat1l
uniprot id: A0A3P9A553
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8010:LOC105013878
gene id: 8010:LOC105013878
uniprot id: A0A3P8ZDQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:casp2
gene id: 8010:casp2
uniprot id: A0A3P8YLL8
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:nkx2.9
gene id: 8010:nkx2.9
uniprot id: A0A3P9AIA3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105024737
gene id: 8010:LOC105024737
uniprot id: A0A3P8XGK3
uniprot id: A0A3P8XGL6
uniprot id: A0A3P8ZJ66
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:LOC105019815
gene id: 8010:LOC105019815
uniprot id: A0A3P8ZMN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:si:rp71-17i16.5
gene id: 8010:si:rp71-17i16.5
uniprot id: A0A3P8Y192
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8010:usp44
gene id: 8010:usp44
uniprot id: A0A3P8XAJ1
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:rin2
gene id: 8010:rin2
uniprot id: A0A3P8Y4Q4
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8010:stim1a
gene id: 8010:stim1a
uniprot id: A0A3P8Y7G4
uniprot id: A0A3P9A116
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:rdh14a
gene id: 8010:rdh14a
uniprot id: A0A3P8YL68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:LOC105020030
gene id: 8010:LOC105020030
uniprot id: A0A3P8Z5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8010:gle1
gene id: 8010:gle1
uniprot id: A0A3P8ZBE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

8010:syngr2a
gene id: 8010:syngr2a
uniprot id: A0A3P8YBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8010:gdi1
gene id: 8010:gdi1
uniprot id: A0A3P8XKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8010:trpc3
gene id: 8010:trpc3
uniprot id: A0A3P8YUS5
uniprot id: A0A3P8YUS9
names: Subcellular Location Annotation
messages: Membrane

8010:irf1b
gene id: 8010:irf1b
uniprot id: A0A3P8Z1A4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:LOC105028431
gene id: 8010:LOC105028431
uniprot id: A0A3P8Z415
uniprot id: A0A3P9AL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:slc6a16a
gene id: 8010:slc6a16a
uniprot id: A0A3P8YAU7
uniprot id: A0A6Q2ZLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:tmem218
gene id: 8010:tmem218
uniprot id: A0A6Q2YER7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8010:rhbdl3
gene id: 8010:rhbdl3
uniprot id: A0A3P8XNR4
uniprot id: A0A3P8ZMM1
uniprot id: A0A3P8ZMW8
uniprot id: A0A3P8ZNM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8010:mbpb
gene id: 8010:mbpb
uniprot id: A0A3P9AH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8010:nck1b
gene id: 8010:nck1b
uniprot id: A0A3P8XG57
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8010:zgc:136971
gene id: 8010:zgc:136971
uniprot id: A0A3P8ZYZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

8010:LOC105013785
gene id: 8010:LOC105013785
uniprot id: A0A3P8XTA3
names: Subcellular Location Annotation
messages: Nucleus

8010:notum1a
gene id: 8010:notum1a
uniprot id: A0A3P9A3J8
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8010:grk7b
gene id: 8010:grk7b
uniprot id: A0A3P9ADF5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8010:scrn2
gene id: 8010:scrn2
uniprot id: A0A3P8ZRY4
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8010:LOC105011516
gene id: 8010:LOC105011516
uniprot id: A0A3P8YWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:lin54
gene id: 8010:lin54
uniprot id: A0A3P8XBH7
uniprot id: A0A3P8ZEV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8010:mctp2a
gene id: 8010:mctp2a
uniprot id: A0A3P8YNB3
names: Subcellular Location Annotation
messages: Membrane

8010:mrps18c
gene id: 8010:mrps18c
uniprot id: A0A3P8ZCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

8010:chrne
gene id: 8010:chrne
uniprot id: A0A3P8XLS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:jakmip2
gene id: 8010:jakmip2
uniprot id: A0A3P8ZAA8
uniprot id: A0A3P8ZAB8
uniprot id: A0A3P8ZBC5
names: Similarity
messages: Belongs to the JAKMIP family.

8010:LOC105007746
gene id: 8010:LOC105007746
uniprot id: A0A3P8ZS56
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:sgsm2
gene id: 8010:sgsm2
uniprot id: A0A3P8ZTC2
uniprot id: A0A3P8ZTT6
names: Similarity
messages: Belongs to the RUTBC family.

8010:LOC105011885
gene id: 8010:LOC105011885
uniprot id: C1BXM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:LOC105031120
gene id: 8010:LOC105031120
uniprot id: A0A3P8YFZ4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:LOC105021494
gene id: 8010:LOC105021494
uniprot id: A0A3P8Y2F4
names: Similarity
messages: Belongs to the apolipoprotein L family.

8010:zdhhc7
gene id: 8010:zdhhc7
uniprot id: A0A6Q2XZD1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:grb7
gene id: 8010:grb7
uniprot id: A0A3P8XPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8010:cntnap2a
gene id: 8010:cntnap2a
uniprot id: A0A3P8ZV58
uniprot id: A0A3P8ZVJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

8010:LOC105016663
gene id: 8010:LOC105016663
uniprot id: A0A3P8YMY3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8010:LOC105013018
gene id: 8010:LOC105013018
uniprot id: A0A6Q2ZQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

8010:grk6
gene id: 8010:grk6
uniprot id: A0A3P8Y4R9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8010:kcnn4
gene id: 8010:kcnn4
uniprot id: A0A3P9AIQ4
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105029772
gene id: 8010:LOC105029772
uniprot id: A0A3P8XQB7
names: Similarity
messages: Belongs to the DSH family.

8010:dlc1
gene id: 8010:dlc1
uniprot id: A0A3P8YRE9
uniprot id: A0A3P9ABR4
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105021634
gene id: 8010:LOC105021634
uniprot id: A0A3P8XPQ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:LOC106023792
gene id: 8010:LOC106023792
uniprot id: A0A3P8ZQV6
names: Similarity
messages: Belongs to the apolipoprotein L family.

8010:lgi3
gene id: 8010:lgi3
uniprot id: A0A3P8YPP0
uniprot id: A0A6Q2Z585
names: Subcellular Location Annotation
messages: Secreted

8010:ppifb
gene id: 8010:ppifb
uniprot id: C1BZ83
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:masp2
gene id: 8010:masp2
uniprot id: A0A3P8Y7Y1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:tuba1c
gene id: 8010:tuba1c
uniprot id: A0A3P8XMB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8010:LOC105013608
gene id: 8010:LOC105013608
uniprot id: A0A3P8XQR7
names: Similarity
messages: Belongs to the NRAMP family.

8010:si:dkey-220k22.1
gene id: 8010:si:dkey-220k22.1
uniprot id: A0A3P9AG99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105016935
gene id: 8010:LOC105016935
uniprot id: A0A3P8Z3E1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8010:elac2
gene id: 8010:elac2
uniprot id: A0A3P8YQI0
uniprot id: A0A3P9ABL8
names: Similarity
messages: Belongs to the RNase Z family.

8010:LOC105016301
gene id: 8010:LOC105016301
uniprot id: A0A3P8XLR3
uniprot id: A0A3P8XM39
uniprot id: A0A3P8XPC0
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8010:LOC105011936
gene id: 8010:LOC105011936
uniprot id: A0A3P8ZBN1
uniprot id: A0A3P8ZBY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:rabep2
gene id: 8010:rabep2
uniprot id: A0A6Q2X360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Early endosome
messages: Endosome
messages: centrosome
messages: cilium basal body

8010:trmt10c
gene id: 8010:trmt10c
uniprot id: A0A3P8XD91
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8010:sat1a.2
gene id: 8010:sat1a.2
uniprot id: C1BWQ1
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

8010:LOC105022340
gene id: 8010:LOC105022340
uniprot id: A0A3P8XML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:susd6
gene id: 8010:susd6
uniprot id: A0A3P8YXA5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:sstr2a
gene id: 8010:sstr2a
uniprot id: A0A3P8ZKP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8010:tpx2
gene id: 8010:tpx2
uniprot id: A0A3P8ZMS4
uniprot id: A0A3P8ZNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

8010:LOC105030498
gene id: 8010:LOC105030498
uniprot id: A0A3P8XKV0
names: Similarity
messages: Belongs to the dickkopf family.

8010:cdc42ep1a
gene id: 8010:cdc42ep1a
uniprot id: A0A3P9AE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8010:mknk1
gene id: 8010:mknk1
uniprot id: A0A3P8YIM5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:cyldl
gene id: 8010:cyldl
uniprot id: A0A6Q2YGF9
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8010:ikbke
gene id: 8010:ikbke
uniprot id: A0A3P8Z9C4
uniprot id: A0A3P9ANR8
names: Subcellular Location Annotation
messages: Cytoplasm

8010:mdm2
gene id: 8010:mdm2
uniprot id: A0A3P8YA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

8010:pde8a
gene id: 8010:pde8a
uniprot id: A0A3P9AFW7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:lipia
gene id: 8010:lipia
uniprot id: A0A3P8Z0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8010:LOC105021142
gene id: 8010:LOC105021142
uniprot id: A0A3P8Z2J8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:LOC105023105
gene id: 8010:LOC105023105
uniprot id: A0A3P8Y3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8010:ndr2
gene id: 8010:ndr2
uniprot id: A0A3P8YAJ8
names: Similarity
messages: Belongs to the TGF-beta family.

8010:hsp90ab1
gene id: 8010:hsp90ab1
uniprot id: A0A3P8Y8B9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8010:tmem115
gene id: 8010:tmem115
uniprot id: A0A3P8Y520
names: Subcellular Location Annotation
messages: Membrane

8010:papss1
gene id: 8010:papss1
uniprot id: A0A3P8YLS8
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8010:gfm2
gene id: 8010:gfm2
uniprot id: A0A3P8XAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

8010:rpl18a
gene id: 8010:rpl18a
uniprot id: A0A3P8ZS64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

8010:gria4a
gene id: 8010:gria4a
uniprot id: A0A3P8Y4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:med29
gene id: 8010:med29
uniprot id: A0A3P9A644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

8010:paqr5b
gene id: 8010:paqr5b
uniprot id: A0A3P8Z1W5
uniprot id: A0A3P9AIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:cacng3b
gene id: 8010:cacng3b
uniprot id: A0A3P8YB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8010:kynu
gene id: 8010:kynu
uniprot id: A0A3P9A5A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105029632
gene id: 8010:LOC105029632
uniprot id: C1BW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

8010:htra1a
gene id: 8010:htra1a
uniprot id: A0A3P8XNC4
names: Similarity
messages: Belongs to the peptidase S1C family.

8010:utp25
gene id: 8010:utp25
uniprot id: A0A3P8YDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

8010:zgc:110410
gene id: 8010:zgc:110410
uniprot id: A0A3P8XA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8010:kcnh2b
gene id: 8010:kcnh2b
uniprot id: A0A3P8Z6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

8010:LOC105029723
gene id: 8010:LOC105029723
uniprot id: A0A3P8XRL4
uniprot id: A0A6Q2ZI44
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8010:c24h4orf48
gene id: 8010:c24h4orf48
uniprot id: A0A6Q2ZGT7
names: Subcellular Location Annotation
messages: Secreted

8010:parpbp
gene id: 8010:parpbp
uniprot id: A0A3P8XBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105011112
gene id: 8010:LOC105011112
uniprot id: A0A3P8Y7Q6
names: Similarity
messages: Belongs to the SH2B adapter family.

8010:kif2c
gene id: 8010:kif2c
uniprot id: A0A3P8Y643
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:LOC105030325
gene id: 8010:LOC105030325
uniprot id: A0A3P8YHA5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:cand2
gene id: 8010:cand2
uniprot id: A0A3P8YST0
uniprot id: A0A3P9AC95
names: Similarity
messages: Belongs to the CAND family.

8010:mfap3l
gene id: 8010:mfap3l
uniprot id: A0A3P8XEZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105025659
gene id: 8010:LOC105025659
uniprot id: A0A3P8YL10
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8010:LOC105006060
gene id: 8010:LOC105006060
uniprot id: A0A6Q2ZL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8010:mtrf1
gene id: 8010:mtrf1
uniprot id: A0A3P8XQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8010:gtf2h1
gene id: 8010:gtf2h1
uniprot id: A0A3P8Z4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8010:vamp4
gene id: 8010:vamp4
uniprot id: A0A3P8XNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8010:hoxb5a
gene id: 8010:hoxb5a
uniprot id: A0A3P9A3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:drd1b
gene id: 8010:drd1b
uniprot id: A0A3P9AMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:prdm1c
gene id: 8010:prdm1c
uniprot id: A0A3P8YIX5
uniprot id: A0A6Q2ZM33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8010:rraga
gene id: 8010:rraga
uniprot id: A0A3P8ZTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8010:LOC105018752
gene id: 8010:LOC105018752
uniprot id: A0A3P8YR44
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

8010:LOC105014695
gene id: 8010:LOC105014695
uniprot id: A0A3P9A2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:crhb
gene id: 8010:crhb
uniprot id: A0A3P9A576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8010:LOC105007181
gene id: 8010:LOC105007181
uniprot id: A0A3P8YCN2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8010:actr6
gene id: 8010:actr6
uniprot id: C1BW50
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

8010:hspb6
gene id: 8010:hspb6
uniprot id: A0A3P8Z1X9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8010:LOC105012469
gene id: 8010:LOC105012469
uniprot id: A0A3P8ZEE2
names: Similarity
messages: Belongs to the IL-6 superfamily.

8010:dock4b
gene id: 8010:dock4b
uniprot id: A0A3P8YIV1
names: Similarity
messages: Belongs to the DOCK family.

8010:prcp
gene id: 8010:prcp
uniprot id: A0A3P8Z5Z9
uniprot id: A0A6Q2WQU7
names: Similarity
messages: Belongs to the peptidase S28 family.

8010:desma
gene id: 8010:desma
uniprot id: A0A3P8Y8W1
uniprot id: A0A3P9A0V4
names: Similarity
messages: Belongs to the intermediate filament family.

8010:chrna2b
gene id: 8010:chrna2b
uniprot id: A0A3P8XLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:LOC105012702
gene id: 8010:LOC105012702
uniprot id: A0A3P8YLC1
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8010:p2ry2.1
gene id: 8010:p2ry2.1
uniprot id: A0A3P8ZVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:adra1ba
gene id: 8010:adra1ba
uniprot id: A0A3P9AJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8010:adam12
gene id: 8010:adam12
uniprot id: A0A3P8ZMX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:pfdn4
gene id: 8010:pfdn4
uniprot id: C1BZ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8010:nkiras2
gene id: 8010:nkiras2
uniprot id: A0A6Q2X3L7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8010:LOC105026079
gene id: 8010:LOC105026079
uniprot id: A0A3P8YPB3
names: Similarity
messages: Belongs to the PPP phosphatase family.

8010:calb1
gene id: 8010:calb1
uniprot id: A0A3P8XVM9
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

8010:emc1
gene id: 8010:emc1
uniprot id: A0A3P9A970
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:akirin2
gene id: 8010:akirin2
uniprot id: A0A3P9A9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8010:lyrm5a
gene id: 8010:lyrm5a
uniprot id: C1BW71
names: Similarity
messages: Belongs to the complex I LYR family.

8010:snx9b
gene id: 8010:snx9b
uniprot id: A0A3P8YEU4
uniprot id: A0A3P9A3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8010:nkx6.2
gene id: 8010:nkx6.2
uniprot id: A0A3P9AD97
names: Subcellular Location Annotation
messages: Nucleus

8010:ndufb11
gene id: 8010:ndufb11
uniprot id: A0A6Q2XN16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane

8010:foxo3b
gene id: 8010:foxo3b
uniprot id: A0A3P8YNF1
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105026202
gene id: 8010:LOC105026202
uniprot id: A0A3P8ZZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8010:LOC105029716
gene id: 8010:LOC105029716
uniprot id: A0A3P8XRX9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8010:zgc:152891
gene id: 8010:zgc:152891
uniprot id: A0A3P8ZLZ6
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:npc1l1
gene id: 8010:npc1l1
uniprot id: A0A3P8ZFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

8010:anapc15
gene id: 8010:anapc15
uniprot id: A0A6Q2ZLT9
uniprot id: C1BYM0
names: Similarity
messages: Belongs to the APC15 family.

8010:LOC105027986
gene id: 8010:LOC105027986
uniprot id: A0A3P8Z729
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105030704
gene id: 8010:LOC105030704
uniprot id: A0A3P8XCU5
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8010:eif2b2
gene id: 8010:eif2b2
uniprot id: A0A3P8XGM4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

8010:LOC105026591
gene id: 8010:LOC105026591
uniprot id: A0A3P8XDA5
names: Similarity
messages: Belongs to the GORASP family.

8010:meox2a
gene id: 8010:meox2a
uniprot id: A0A3P9A4M0
names: Subcellular Location Annotation
messages: Nucleus

8010:lars1b
gene id: 8010:lars1b
uniprot id: A0A3P9AM26
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8010:jag1b
gene id: 8010:jag1b
uniprot id: A0A3P9A9L9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:gdap1l1
gene id: 8010:gdap1l1
uniprot id: A0A3P8XM65
names: Similarity
messages: Belongs to the GST superfamily.

8010:pparg
gene id: 8010:pparg
uniprot id: A0A3P8YB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:ptpn21
gene id: 8010:ptpn21
uniprot id: A0A3P8XLZ9
uniprot id: A0A3P8ZLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8010:LOC105027784
gene id: 8010:LOC105027784
uniprot id: A0A3P8Z4D7
uniprot id: A0A3P9ALA6
names: Similarity
messages: Belongs to the globin family.

8010:ube2d1b
gene id: 8010:ube2d1b
uniprot id: A0A3P8YNR8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:LOC105026875
gene id: 8010:LOC105026875
uniprot id: A0A3P8YWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:si:dkey-221l4.11
gene id: 8010:si:dkey-221l4.11
uniprot id: A0A3P8YFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:fmoda
gene id: 8010:fmoda
uniprot id: A0A3P8XA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

8010:LOC105019719
gene id: 8010:LOC105019719
uniprot id: A0A3P8ZCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8010:mstnb
gene id: 8010:mstnb
uniprot id: A0A3P8YCQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8010:acbd4
gene id: 8010:acbd4
uniprot id: A0A3P8XHF8
uniprot id: A0A3P8XHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

8010:ogdha
gene id: 8010:ogdha
uniprot id: A0A3P8XTZ4
uniprot id: A0A3P8XU17
uniprot id: A0A3P8XXG8
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8010:trmt11
gene id: 8010:trmt11
uniprot id: A0A3P8XHL2
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

8010:polr3d
gene id: 8010:polr3d
uniprot id: A0A3P9A9D2
names: Subcellular Location Annotation
messages: Nucleus

8010:slc52a2
gene id: 8010:slc52a2
uniprot id: A0A3P8YRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8010:unc119a
gene id: 8010:unc119a
uniprot id: A0A3P8XPB7
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8010:b4galt5
gene id: 8010:b4galt5
uniprot id: A0A3P8X9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8010:tent5aa
gene id: 8010:tent5aa
uniprot id: A0A3P9AIC7
names: Similarity
messages: Belongs to the TENT family.

8010:parp10
gene id: 8010:parp10
uniprot id: A0A3P8ZZ13
names: Similarity
messages: Belongs to the ARTD/PARP family.

8010:slbp2
gene id: 8010:slbp2
uniprot id: A0A3P9AK80
names: Similarity
messages: Belongs to the SLBP family.

8010:fam32a
gene id: 8010:fam32a
uniprot id: C1BZ51
names: Similarity
messages: Belongs to the FAM32 family.

8010:LOC105017364
gene id: 8010:LOC105017364
uniprot id: A0A3P8XFS0
names: Similarity
messages: Belongs to the Bcl-2 family.

8010:LOC105023653
gene id: 8010:LOC105023653
uniprot id: A0A3P8ZJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:vps45
gene id: 8010:vps45
uniprot id: A0A3P8YLE9
uniprot id: A0A3P9A7J6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8010:pparaa
gene id: 8010:pparaa
uniprot id: A0A3P8XRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:galk2
gene id: 8010:galk2
uniprot id: A0A3P8XLZ0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

8010:adrb1
gene id: 8010:adrb1
uniprot id: A0A3P9AQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:pigs
gene id: 8010:pigs
uniprot id: A0A3P9ACS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:hdac8
gene id: 8010:hdac8
uniprot id: A0A3P9A210
uniprot id: A0A3P9A218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

8010:LOC105020997
gene id: 8010:LOC105020997
uniprot id: A0A3P8YMJ2
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:bves
gene id: 8010:bves
uniprot id: A0A3P9AM95
names: Similarity
messages: Belongs to the popeye family.

8010:LOC105023864
gene id: 8010:LOC105023864
uniprot id: A0A3P8ZYH8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:rnasekb
gene id: 8010:rnasekb
uniprot id: A0A6Q2XMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8010:LOC105005782
gene id: 8010:LOC105005782
uniprot id: A0A3P8YYC6
uniprot id: A0A6Q2XE35
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:si:ch211-253b8.5
gene id: 8010:si:ch211-253b8.5
uniprot id: A0A3P8XJH3
names: Similarity
messages: Belongs to the dysbindin family.

8010:LOC105021664
gene id: 8010:LOC105021664
uniprot id: A0A3P9AIV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8010:LOC105027502
gene id: 8010:LOC105027502
uniprot id: A0A3P8YFK2
names: Subcellular Location Annotation
messages: Nucleus

8010:nkain4
gene id: 8010:nkain4
uniprot id: A0A3P8XBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8010:LOC105014820
gene id: 8010:LOC105014820
uniprot id: A0A3P8Y1H8
uniprot id: A0A3P8ZWC3
names: Similarity
messages: Belongs to the syntaxin family.

8010:kpna5
gene id: 8010:kpna5
uniprot id: A0A3P8XH37
uniprot id: A0A6Q2XI70
names: Similarity
messages: Belongs to the importin alpha family.

8010:dlx2a
gene id: 8010:dlx2a
uniprot id: A0A3P9AIY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8010:ovca2
gene id: 8010:ovca2
uniprot id: A0A6Q2WWB1
names: Similarity
messages: Belongs to the LovG family.

8010:syt1a
gene id: 8010:syt1a
uniprot id: A0A3P8X949
uniprot id: A0A3P8ZCZ4
uniprot id: A0A3P8ZDE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8010:LOC105015114
gene id: 8010:LOC105015114
uniprot id: A0A3P8YFK1
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105015953
gene id: 8010:LOC105015953
uniprot id: A0A3P8YMF3
uniprot id: A0A3P9A9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8010:LOC105021012
gene id: 8010:LOC105021012
uniprot id: A0A3P8Y734
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8010:smu1a
gene id: 8010:smu1a
uniprot id: A0A3P9ALY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8010:fbl
gene id: 8010:fbl
uniprot id: A0A3P9ALP4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

8010:cers4a
gene id: 8010:cers4a
uniprot id: A0A3P8Z0W3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:ches1
gene id: 8010:ches1
uniprot id: A0A3P8ZPM7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105019666
gene id: 8010:LOC105019666
uniprot id: A0A3P8Z093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

8010:LOC105020203
gene id: 8010:LOC105020203
uniprot id: A0A3P8ZKD2
names: Similarity
messages: Belongs to the PAL/histidase family.

8010:arf2b
gene id: 8010:arf2b
uniprot id: A0A3P8ZMQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8010:LOC105031648
gene id: 8010:LOC105031648
uniprot id: A0A3P8ZZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105010520
gene id: 8010:LOC105010520
uniprot id: A0A3P8XGB9
names: Similarity
messages: Belongs to the SMEK family.

8010:ribc1
gene id: 8010:ribc1
uniprot id: A0A3P8XWR8
names: Similarity
messages: Belongs to the RIB43A family.

8010:LOC105026746
gene id: 8010:LOC105026746
uniprot id: A0A3P8Y5S4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8010:LOC105020091
gene id: 8010:LOC105020091
uniprot id: A0A3P8XA70
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:mre11a
gene id: 8010:mre11a
uniprot id: A0A3P8Y040
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

8010:inhbb
gene id: 8010:inhbb
uniprot id: A0A3P8XRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8010:fam114a2
gene id: 8010:fam114a2
uniprot id: A0A3P8Y3X4
names: Similarity
messages: Belongs to the FAM114 family.

8010:braf
gene id: 8010:braf
uniprot id: A0A3P8Y4P5
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8010:ube2d4
gene id: 8010:ube2d4
uniprot id: A0A6Q2YCR3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:rps15a
gene id: 8010:rps15a
uniprot id: C1BWB5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

8010:ndufaf2
gene id: 8010:ndufaf2
uniprot id: A0A6Q2XFT4
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

8010:c3h7orf25
gene id: 8010:c3h7orf25
uniprot id: A0A3P8ZJ94
names: Similarity
messages: Belongs to the UPF0415 family.

8010:nr2c1
gene id: 8010:nr2c1
uniprot id: A0A3P8ZPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:zgc:103586
gene id: 8010:zgc:103586
uniprot id: A0A3P9AEQ2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

8010:cdc5l
gene id: 8010:cdc5l
uniprot id: A0A3P9A2H0
uniprot id: A0A6Q2XDM5
names: Similarity
messages: Belongs to the CEF1 family.

8010:cry5
gene id: 8010:cry5
uniprot id: A0A3P8YSL1
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

8010:gal3st3
gene id: 8010:gal3st3
uniprot id: A0A6Q2YJA6
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8010:eve1
gene id: 8010:eve1
uniprot id: A0A3P8YFZ0
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105017586
gene id: 8010:LOC105017586
uniprot id: C1BXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8010:mttp
gene id: 8010:mttp
uniprot id: A0A3P9ACT0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:slc40a1
gene id: 8010:slc40a1
uniprot id: A0A3P8YCH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

8010:LOC105018631
gene id: 8010:LOC105018631
uniprot id: A0A3P8XDT6
uniprot id: A0A6Q2YL68
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8010:mvp
gene id: 8010:mvp
uniprot id: A0A3P9ANW7
uniprot id: A0A3P9ANX2
names: Subcellular Location Annotation
messages: Cytoplasm

8010:cops4
gene id: 8010:cops4
uniprot id: A0A3P8XBK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8010:LOC105007747
gene id: 8010:LOC105007747
uniprot id: A0A3P8XV92
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:ppiab
gene id: 8010:ppiab
uniprot id: A0A3P9ANT1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:raraa
gene id: 8010:raraa
uniprot id: A0A3P8Y5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:LOC105017544
gene id: 8010:LOC105017544
uniprot id: A0A3P8ZXX5
names: Subcellular Location Annotation
messages: Nucleus

8010:ska3
gene id: 8010:ska3
uniprot id: A0A3P8XPU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

8010:tpi1a
gene id: 8010:tpi1a
uniprot id: A0A3P9AIV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8010:LOC105022742
gene id: 8010:LOC105022742
uniprot id: A0A3P8YX69
names: Subcellular Location Annotation
messages: Membrane

8010:esrrd
gene id: 8010:esrrd
uniprot id: A0A3P9A0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8010:ireb2
gene id: 8010:ireb2
uniprot id: A0A3P8Z9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

8010:cdc14b
gene id: 8010:cdc14b
uniprot id: A0A3P8XD50
uniprot id: A0A3P8ZCL3
uniprot id: A0A3P8ZCM6
uniprot id: A0A6Q2WSY2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

8010:xrcc3
gene id: 8010:xrcc3
uniprot id: A0A3P8XPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

8010:LOC105012278
gene id: 8010:LOC105012278
uniprot id: A0A3P8ZLB1
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105028615
gene id: 8010:LOC105028615
uniprot id: A0A3P8YE68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

8010:gpx9
gene id: 8010:gpx9
uniprot id: A0A3P9A1R4
uniprot id: A0A6Q2YEP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Belongs to the glutathione peroxidase family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:tfpia
gene id: 8010:tfpia
uniprot id: A0A3P8YNJ0
uniprot id: A0A3P9ABF2
names: Subcellular Location Annotation
messages: Secreted

8010:lamb2l
gene id: 8010:lamb2l
uniprot id: A0A3P8Y1G7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8010:cmasa
gene id: 8010:cmasa
uniprot id: A0A3P8Z166
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

8010:sorcs2
gene id: 8010:sorcs2
uniprot id: A0A3P8Y4A4
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8010:LOC105020023
gene id: 8010:LOC105020023
uniprot id: A0A3P8Z0Q5
uniprot id: A0A3P9AIL4
names: Subcellular Location Annotation
messages: Nucleus

8010:nfil3
gene id: 8010:nfil3
uniprot id: A0A3P9A9F0
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8010:itga5
gene id: 8010:itga5
uniprot id: A0A3P8ZFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:LOC105022190
gene id: 8010:LOC105022190
uniprot id: A0A3P9AKL2
names: Similarity
messages: Belongs to the peptidase A1 family.

8010:dldh
gene id: 8010:dldh
uniprot id: A0A3P8ZLE3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

8010:LOC105025840
gene id: 8010:LOC105025840
uniprot id: A0A3P8YLC0
names: Subcellular Location Annotation
messages: Nucleus

8010:hs3st1l2
gene id: 8010:hs3st1l2
uniprot id: A0A3P8XJ94
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:megf10
gene id: 8010:megf10
uniprot id: A0A3P9ADP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:g6pca.1
gene id: 8010:g6pca.1
uniprot id: A0A3P8XQL3
uniprot id: A0A3P8XQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8010:acadvl
gene id: 8010:acadvl
uniprot id: A0A3P8XQP4
uniprot id: A0A6Q2ZC15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:etf1b
gene id: 8010:etf1b
uniprot id: A0A3P9A0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

8010:mogat3a
gene id: 8010:mogat3a
uniprot id: A0A3P8Z1K2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105014167
gene id: 8010:LOC105014167
uniprot id: A0A3P8X9Y2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8010:senp3b
gene id: 8010:senp3b
uniprot id: A0A3P8ZTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

8010:tbrg1
gene id: 8010:tbrg1
uniprot id: A0A3P8YMG3
uniprot id: A0A3P8YNQ9
uniprot id: A0A3P9AAH4
names: Subcellular Location Annotation
messages: Nucleus

8010:zgc:56095
gene id: 8010:zgc:56095
uniprot id: A0A3P8XPH3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:nxph1
gene id: 8010:nxph1
uniprot id: A0A3P8Z7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8010:mylk5
gene id: 8010:mylk5
uniprot id: A0A3P8YV03
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

8010:kif20bb
gene id: 8010:kif20bb
uniprot id: A0A3P8ZFB7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:isl1
gene id: 8010:isl1
uniprot id: A0A3P8Z5V2
names: Subcellular Location Annotation
messages: Nucleus

8010:igf1ra
gene id: 8010:igf1ra
uniprot id: A0A3P8YMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:slc7a14a
gene id: 8010:slc7a14a
uniprot id: A0A3P8XMW1
names: Subcellular Location Annotation
messages: Membrane

8010:elk1
gene id: 8010:elk1
uniprot id: A0A3P8ZJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:hrh1
gene id: 8010:hrh1
uniprot id: A0A3P8YIV5
uniprot id: A0A3P9A5K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8010:xylb
gene id: 8010:xylb
uniprot id: A0A3P8YRX4
uniprot id: A0A6Q2XIV6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

8010:prkar2aa
gene id: 8010:prkar2aa
uniprot id: A0A3P8Y609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8010:tiprl
gene id: 8010:tiprl
uniprot id: A0A3P9ABQ9
names: Similarity
messages: Belongs to the TIP41 family.

8010:cenpi
gene id: 8010:cenpi
uniprot id: A0A3P8ZH75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

8010:dkk1b
gene id: 8010:dkk1b
uniprot id: A0A3P8XAJ8
names: Similarity
messages: Belongs to the dickkopf family.

8010:gaa
gene id: 8010:gaa
uniprot id: A0A3P8XK16
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:si:dkey-202e22.2
gene id: 8010:si:dkey-202e22.2
uniprot id: A0A3P8ZLQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:csnk1a1
gene id: 8010:csnk1a1
uniprot id: A0A3P9A2U0
uniprot id: A0A6Q2WVW7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:zgc:153846
gene id: 8010:zgc:153846
uniprot id: A0A3P8XQ20
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:slc14a2
gene id: 8010:slc14a2
uniprot id: A0A3P8Y1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

8010:npnta
gene id: 8010:npnta
uniprot id: A0A6Q2XL27
uniprot id: A0A6Q2Y794
uniprot id: A0A6Q2ZE62
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:gtf2h4
gene id: 8010:gtf2h4
uniprot id: A0A3P8YPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

8010:ehf
gene id: 8010:ehf
uniprot id: A0A3P8XIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:zgc:92591
gene id: 8010:zgc:92591
uniprot id: A0A3P9AJQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:rbbp4
gene id: 8010:rbbp4
uniprot id: A0A3P9A9U0
names: Subcellular Location Annotation
messages: Nucleus

8010:nsmce2
gene id: 8010:nsmce2
uniprot id: A0A3P8ZFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

8010:alg14
gene id: 8010:alg14
uniprot id: A0A6Q2ZPV6
uniprot id: C1BWE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Membrane
messages: Nucleus membrane

8010:fzd7a
gene id: 8010:fzd7a
uniprot id: A0A3P8ZXJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:unc50
gene id: 8010:unc50
uniprot id: C1BXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

8010:LOC105005922
gene id: 8010:LOC105005922
uniprot id: A0A3P8YQ84
uniprot id: A0A3P9ACA0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8010:LOC105010568
gene id: 8010:LOC105010568
uniprot id: A0A3P8XLA7
uniprot id: A0A3P8XQ28
names: Similarity
messages: Belongs to the FAM53 family.

8010:mat2aa
gene id: 8010:mat2aa
uniprot id: A0A3P9AFF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8010:LOC106024317
gene id: 8010:LOC106024317
uniprot id: A0A3P9A4I2
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

8010:gata1a
gene id: 8010:gata1a
uniprot id: A0A3P8XFN9
names: Subcellular Location Annotation
messages: Nucleus

8010:tmeff2a
gene id: 8010:tmeff2a
uniprot id: A0A3P8XZW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:gys1
gene id: 8010:gys1
uniprot id: A0A3P8YBI9
uniprot id: A0A6Q2YPB1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8010:fgfr1op2
gene id: 8010:fgfr1op2
uniprot id: A0A3P8XAA4
names: Similarity
messages: Belongs to the SIKE family.

8010:dpy19l1l
gene id: 8010:dpy19l1l
uniprot id: A0A3P8Y005
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8010:ano3
gene id: 8010:ano3
uniprot id: A0A3P8YZ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8010:eif3i
gene id: 8010:eif3i
uniprot id: A0A3P8YRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8010:hpxb
gene id: 8010:hpxb
uniprot id: A0A3P8XVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8010:wars1
gene id: 8010:wars1
uniprot id: A0A3P8YHB2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8010:hmox2b
gene id: 8010:hmox2b
uniprot id: A0A3P9A5T4
names: Similarity
messages: Belongs to the heme oxygenase family.

8010:slc25a3a
gene id: 8010:slc25a3a
uniprot id: A0A3P8Y3X2
uniprot id: A0A3P8Y3X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

8010:clic5a
gene id: 8010:clic5a
uniprot id: A0A3P9A2R0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8010:bgnb
gene id: 8010:bgnb
uniprot id: A0A3P8Y296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

8010:LOC105014600
gene id: 8010:LOC105014600
uniprot id: A0A3P8YVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8010:ergic2
gene id: 8010:ergic2
uniprot id: C1BZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8010:osbpl5
gene id: 8010:osbpl5
uniprot id: A0A3P9AL60
uniprot id: A0A3P9AL81
names: Similarity
messages: Belongs to the OSBP family.

8010:washc3
gene id: 8010:washc3
uniprot id: A0A3P8XBP9
names: Similarity
messages: Belongs to the CCDC53 family.

8010:zgc:101783
gene id: 8010:zgc:101783
uniprot id: A0A3P8XBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8010:nedd8l
gene id: 8010:nedd8l
uniprot id: C1BWH3
names: Similarity
messages: Belongs to the ubiquitin family.

8010:dicer1
gene id: 8010:dicer1
uniprot id: A0A6Q2Z427
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

8010:slc24a4b
gene id: 8010:slc24a4b
uniprot id: A0A3P8XSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:cdv3
gene id: 8010:cdv3
uniprot id: A0A3P8XTD3
names: Similarity
messages: Belongs to the CDV3 family.

8010:otpa
gene id: 8010:otpa
uniprot id: A0A3P8ZMR3
names: Subcellular Location Annotation
messages: Nucleus

8010:eif3c
gene id: 8010:eif3c
uniprot id: A0A3P8Z380
uniprot id: A0A3P8Z449
uniprot id: A0A3P9AJW3
uniprot id: A0A3P9AKL5
uniprot id: A0A3P9AKX5
uniprot id: A0A6Q2XYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8010:LOC105016591
gene id: 8010:LOC105016591
uniprot id: A0A3P8Z5R5
names: Subcellular Location Annotation
messages: Nucleus

8010:aldh1a3
gene id: 8010:aldh1a3
uniprot id: A0A3P8Z9D8
uniprot id: A0A3P9APR1
uniprot id: A0A6Q2X4F8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:LOC105013914
gene id: 8010:LOC105013914
uniprot id: A0A3P8XFG2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105013248
gene id: 8010:LOC105013248
uniprot id: A0A3P9A4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:crygmxl2
gene id: 8010:crygmxl2
uniprot id: A0A3P8XNM3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:lamc1
gene id: 8010:lamc1
uniprot id: A0A3P8ZUS7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8010:smpd1
gene id: 8010:smpd1
uniprot id: A0A3P8YTY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.

8010:LOC105030515
gene id: 8010:LOC105030515
uniprot id: A0A3P8ZNE8
names: Similarity
messages: Belongs to the peptidase C1 family.

8010:LOC105020512
gene id: 8010:LOC105020512
uniprot id: A0A3P8YD95
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:LOC105005853
gene id: 8010:LOC105005853
uniprot id: A0A3P8XIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8010:mcm9
gene id: 8010:mcm9
uniprot id: A0A3P8YZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8010:pex2
gene id: 8010:pex2
uniprot id: A0A3P8XWW1
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

8010:elp4
gene id: 8010:elp4
uniprot id: A0A3P8Z714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

8010:dpm2
gene id: 8010:dpm2
uniprot id: A0A3P8Z331
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

8010:paqr3a
gene id: 8010:paqr3a
uniprot id: A0A3P8YAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:foxa1
gene id: 8010:foxa1
uniprot id: A0A3P8ZE73
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105011482
gene id: 8010:LOC105011482
uniprot id: A0A3P8Z407
uniprot id: A0A3P8Z412
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105008385
gene id: 8010:LOC105008385
uniprot id: A0A3P8X7A7
uniprot id: A0A3P8X9L7
uniprot id: A0A3P8ZB50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8010:ints12
gene id: 8010:ints12
uniprot id: A0A3P9A8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

8010:LOC105008384
gene id: 8010:LOC105008384
uniprot id: A0A3P8ZB92
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8010:LOC105020661
gene id: 8010:LOC105020661
uniprot id: A0A3P9A499
names: Subcellular Location Annotation
messages: Nucleus

8010:fam110a
gene id: 8010:fam110a
uniprot id: A0A3P8Z4B3
names: Similarity
messages: Belongs to the FAM110 family.

8010:LOC105013116
gene id: 8010:LOC105013116
uniprot id: A0A3P8ZNN9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

8010:dcp2
gene id: 8010:dcp2
uniprot id: A0A3P8YKM6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

8010:LOC105022957
gene id: 8010:LOC105022957
uniprot id: A0A3P8YTX6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:nr2f1a
gene id: 8010:nr2f1a
uniprot id: A0A3P9AA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:naaladl1
gene id: 8010:naaladl1
uniprot id: A0A3P8Z232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8010:txn
gene id: 8010:txn
uniprot id: C1BX46
names: Similarity
messages: Belongs to the thioredoxin family.

8010:slc25a25a
gene id: 8010:slc25a25a
uniprot id: A0A3P8ZBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:LOC105019157
gene id: 8010:LOC105019157
uniprot id: A0A3P8ZQX6
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105006826
gene id: 8010:LOC105006826
uniprot id: A0A3P8YWP5
uniprot id: A0A3P9AFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane
messages: Reversible hydration of carbon dioxide.

8010:sept4b
gene id: 8010:sept4b
uniprot id: A0A6Q2Y4W8
uniprot id: A0A6Q2YTC4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8010:ccr6a
gene id: 8010:ccr6a
uniprot id: A0A3P8ZU65
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:skap1
gene id: 8010:skap1
uniprot id: A0A3P8XW85
names: Similarity
messages: Belongs to the SKAP family.

8010:agxta
gene id: 8010:agxta
uniprot id: A0A3P8ZLW9
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8010:pnp4b
gene id: 8010:pnp4b
uniprot id: A0A3P8ZT31
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

8010:ppfibp1a
gene id: 8010:ppfibp1a
uniprot id: A0A3P8X8Z4
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8010:si:dkey-246g23.4
gene id: 8010:si:dkey-246g23.4
uniprot id: A0A3P8YF13
names: Subcellular Location Annotation
messages: Membrane

8010:recql5
gene id: 8010:recql5
uniprot id: A0A3P9AA42
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8010:loxa
gene id: 8010:loxa
uniprot id: A0A3P9AFE0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8010:ifrd2
gene id: 8010:ifrd2
uniprot id: A0A3P8ZXN6
uniprot id: A0A3P8ZXQ3
names: Similarity
messages: Belongs to the IFRD family.

8010:etsrp
gene id: 8010:etsrp
uniprot id: A0A3P9A782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:mbtps1
gene id: 8010:mbtps1
uniprot id: A0A3P9A9K1
names: Similarity
messages: Belongs to the peptidase S8 family.

8010:ddost
gene id: 8010:ddost
uniprot id: A0A3P8YJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

8010:ptcd3
gene id: 8010:ptcd3
uniprot id: A0A3P8Y8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

8010:zgc:165508
gene id: 8010:zgc:165508
uniprot id: A0A3P9A5Y4
uniprot id: A0A3P9A5Y8
names: Similarity
messages: Belongs to the FAM131 family.

8010:oprd1a
gene id: 8010:oprd1a
uniprot id: A0A3P8ZXG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:cacnb2a
gene id: 8010:cacnb2a
uniprot id: A0A3P8Z2Q6
uniprot id: A0A3P8Z3J1
uniprot id: A0A3P8Z3K7
uniprot id: A0A3P9AK83
names: Function
names: Similarity
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

8010:LOC105019950
gene id: 8010:LOC105019950
uniprot id: A0A3P9ACE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8010:gpkow
gene id: 8010:gpkow
uniprot id: A0A3P9AKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

8010:ovol1a
gene id: 8010:ovol1a
uniprot id: A0A3P8XW66
names: Subcellular Location Annotation
messages: Nucleus

8010:cryaa
gene id: 8010:cryaa
uniprot id: A0A3P8ZZ87
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Belongs to the small heat shock protein (HSP20) family.

8010:apex2
gene id: 8010:apex2
uniprot id: A0A3P8Z0Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

8010:LOC105024961
gene id: 8010:LOC105024961
uniprot id: A0A3P8YS28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:slc24a3
gene id: 8010:slc24a3
uniprot id: A0A3P8ZZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:tmx2a
gene id: 8010:tmx2a
uniprot id: C1BYN9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8010:eif4eb
gene id: 8010:eif4eb
uniprot id: A0A3P8YCK8
uniprot id: A0A6Q2ZJZ4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8010:fam3c
gene id: 8010:fam3c
uniprot id: A0A3P8X7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8010:LOC105020024
gene id: 8010:LOC105020024
uniprot id: A0A3P8YZ68
uniprot id: A0A3P9AI17
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

8010:LOC105014903
gene id: 8010:LOC105014903
uniprot id: A0A3P8Z0F0
uniprot id: A0A3P9AIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8010:mettl15
gene id: 8010:mettl15
uniprot id: A0A3P8XZD1
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8010:LOC105025850
gene id: 8010:LOC105025850
uniprot id: A0A3P8Z083
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8010:pym1
gene id: 8010:pym1
uniprot id: A0A3P9AQ35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

8010:nudt12
gene id: 8010:nudt12
uniprot id: A0A3P8XR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

8010:LOC105011864
gene id: 8010:LOC105011864
uniprot id: C1BXN1
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

8010:nkap
gene id: 8010:nkap
uniprot id: A0A3P8YZ43
names: Similarity
messages: Belongs to the NKAP family.

8010:mcoln3a
gene id: 8010:mcoln3a
uniprot id: A0A3P8ZAC5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8010:adss2
gene id: 8010:adss2
uniprot id: A0A3P8YBA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8010:ctnnd2b
gene id: 8010:ctnnd2b
uniprot id: A0A3P8YBS2
uniprot id: A0A3P8YE18
names: Similarity
messages: Belongs to the beta-catenin family.

8010:rtraf
gene id: 8010:rtraf
uniprot id: C1BZG5
names: Similarity
messages: Belongs to the RTRAF family.

8010:LOC105021027
gene id: 8010:LOC105021027
uniprot id: A0A3P8YNN2
uniprot id: A0A3P9AB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

8010:LOC105014804
gene id: 8010:LOC105014804
uniprot id: A0A3P8XEP5
uniprot id: A0A3P8ZDQ1
uniprot id: A0A3P8ZE29
uniprot id: A0A3P8ZFD0
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

8010:sema6a
gene id: 8010:sema6a
uniprot id: A0A3P8YT73
uniprot id: A0A3P8YT90
uniprot id: A0A3P8YTA0
uniprot id: A0A6Q2WQD2
uniprot id: A0A6Q2YK04
uniprot id: A0A6Q2Z607
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:parp16
gene id: 8010:parp16
uniprot id: A0A3P8ZJ74
names: Similarity
messages: Belongs to the ARTD/PARP family.

8010:LOC106024889
gene id: 8010:LOC106024889
uniprot id: A0A6Q2YSQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:serinc1
gene id: 8010:serinc1
uniprot id: A0A3P9AHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8010:aga
gene id: 8010:aga
uniprot id: A0A3P9AHU3
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8010:LOC105017253
gene id: 8010:LOC105017253
uniprot id: A0A3P8YZH2
names: Subcellular Location Annotation
messages: Membrane

8010:cldn15a
gene id: 8010:cldn15a
uniprot id: A0A3P8YU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:cfl2
gene id: 8010:cfl2
uniprot id: A0A3P8ZG71
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8010:LOC105018316
gene id: 8010:LOC105018316
uniprot id: A0A3P8XNE7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:acsl5
gene id: 8010:acsl5
uniprot id: A0A3P8XMM3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8010:LOC105018542
gene id: 8010:LOC105018542
uniprot id: C1BYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8010:LOC105023882
gene id: 8010:LOC105023882
uniprot id: C1BZK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ston2
gene id: 8010:ston2
uniprot id: A0A3P8YN02
uniprot id: A0A3P9A8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

8010:poll
gene id: 8010:poll
uniprot id: A0A3P8ZGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

8010:crcp
gene id: 8010:crcp
uniprot id: C1BY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

8010:irx2a
gene id: 8010:irx2a
uniprot id: A0A3P8ZGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8010:vgll1
gene id: 8010:vgll1
uniprot id: A0A3P8ZG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8010:irf2bp2a
gene id: 8010:irf2bp2a
uniprot id: A0A3P9ACH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8010:xylt2
gene id: 8010:xylt2
uniprot id: A0A3P8YM62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8010:eif3ja
gene id: 8010:eif3ja
uniprot id: A0A3P8XIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8010:LOC105019162
gene id: 8010:LOC105019162
uniprot id: A0A3P8ZRR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8010:trabd2b
gene id: 8010:trabd2b
uniprot id: A0A3P9A4R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8010:cav1
gene id: 8010:cav1
uniprot id: A0A6Q2XHP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: Membrane raft
messages: caveola

8010:dhrs9
gene id: 8010:dhrs9
uniprot id: C1BYZ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:uvssa
gene id: 8010:uvssa
uniprot id: A0A3P8Y7S7
names: Similarity
messages: Belongs to the UVSSA family.

8010:htr4
gene id: 8010:htr4
uniprot id: A0A3P8YF61
uniprot id: A0A3P8YGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8010:LOC105025910
gene id: 8010:LOC105025910
uniprot id: A0A3P8Y199
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:svbp
gene id: 8010:svbp
uniprot id: A0A3P8Y7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

8010:cmtm8b
gene id: 8010:cmtm8b
uniprot id: A0A3P8XG68
names: Subcellular Location Annotation
messages: Membrane

8010:glyr1
gene id: 8010:glyr1
uniprot id: A0A3P8ZWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

8010:sgms2a
gene id: 8010:sgms2a
uniprot id: A0A3P8YKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8010:LOC105005771
gene id: 8010:LOC105005771
uniprot id: A0A3P8ZT73
uniprot id: A0A6Q2YV26
names: Subcellular Location Annotation
messages: Membrane

8010:ctu2
gene id: 8010:ctu2
uniprot id: A0A3P9ADT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

8010:LOC109616147
gene id: 8010:LOC109616147
uniprot id: A0A3P8ZES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8010:riox1
gene id: 8010:riox1
uniprot id: A0A3P8ZQZ4
uniprot id: A0A6Q2YRN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8010:phf1
gene id: 8010:phf1
uniprot id: A0A3P8ZZF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

8010:usp4
gene id: 8010:usp4
uniprot id: A0A3P8YPZ9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:polm
gene id: 8010:polm
uniprot id: A0A3P9AQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

8010:ca14
gene id: 8010:ca14
uniprot id: A0A3P8YCR8
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8010:csrnp2
gene id: 8010:csrnp2
uniprot id: A0A3P8XCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8010:si:ch211-1i11.3
gene id: 8010:si:ch211-1i11.3
uniprot id: A0A3P9A9W0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8010:vgll4l
gene id: 8010:vgll4l
uniprot id: A0A3P8YT50
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8010:fam161b
gene id: 8010:fam161b
uniprot id: A0A3P8XUB3
names: Similarity
messages: Belongs to the FAM161 family.

8010:clns1a
gene id: 8010:clns1a
uniprot id: A0A3P8XLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

8010:LOC105016890
gene id: 8010:LOC105016890
uniprot id: C1BYX4
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8010:ppp3r1b
gene id: 8010:ppp3r1b
uniprot id: A0A3P8ZXY1
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

8010:cdkal1
gene id: 8010:cdkal1
uniprot id: A0A3P8ZEJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

8010:sec24a
gene id: 8010:sec24a
uniprot id: A0A3P8Z0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8010:pole2
gene id: 8010:pole2
uniprot id: A0A3P8YII0
uniprot id: A0A6Q2ZFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

8010:alx3
gene id: 8010:alx3
uniprot id: A0A3P9A7W3
names: Subcellular Location Annotation
messages: Nucleus

8010:polr3g
gene id: 8010:polr3g
uniprot id: A0A3P8YQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

8010:ilk
gene id: 8010:ilk
uniprot id: A0A3P8Y804
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

8010:LOC105005610
gene id: 8010:LOC105005610
uniprot id: A0A3P8YP66
uniprot id: A0A3P8YP85
names: Subcellular Location Annotation
messages: Membrane

8010:btbd10a
gene id: 8010:btbd10a
uniprot id: A0A3P8YDU2
uniprot id: A0A6Q2ZJ32
names: Subcellular Location Annotation
messages: Cytoplasm

8010:lyplal1
gene id: 8010:lyplal1
uniprot id: A0A3P8YZI4
uniprot id: A0A6Q2Y042
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8010:LOC105011275
gene id: 8010:LOC105011275
uniprot id: A0A3P8Z425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:mustn1a
gene id: 8010:mustn1a
uniprot id: A0A3P9A8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

8010:casq2
gene id: 8010:casq2
uniprot id: A0A3P8XL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8010:top3a
gene id: 8010:top3a
uniprot id: A0A3P8ZYF4
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8010:orai2
gene id: 8010:orai2
uniprot id: A0A6Q2Z4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8010:tapt1b
gene id: 8010:tapt1b
uniprot id: A0A3P8ZKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

8010:tarbp2
gene id: 8010:tarbp2
uniprot id: A0A3P8Y0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

8010:LOC105012173
gene id: 8010:LOC105012173
uniprot id: A0A3P9APQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8010:nos1
gene id: 8010:nos1
uniprot id: A0A3P8XJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: dendritic spine
messages: sarcolemma

8010:cmc2
gene id: 8010:cmc2
uniprot id: A0A3P8ZV45
uniprot id: A0A6Q2XMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8010:rpl32
gene id: 8010:rpl32
uniprot id: A0A6Q2XWB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

8010:LOC105029132
gene id: 8010:LOC105029132
uniprot id: A0A3P9A954
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8010:st7l
gene id: 8010:st7l
uniprot id: A0A3P9AKK9
uniprot id: A0A6Q2WXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

8010:LOC105024802
gene id: 8010:LOC105024802
uniprot id: A0A3P8XVT8
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8010:rexo4
gene id: 8010:rexo4
uniprot id: A0A3P8XC13
names: Similarity
messages: Belongs to the REXO4 family.

8010:csf1ra
gene id: 8010:csf1ra
uniprot id: A0A3P8YJM4
uniprot id: A0A3P9A7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:ubald2
gene id: 8010:ubald2
uniprot id: A0A3P8YND9
names: Similarity
messages: Belongs to the UBALD family.

8010:LOC109614567
gene id: 8010:LOC109614567
uniprot id: A0A3P8XCX0
names: Similarity
messages: Belongs to the serpin family.

8010:psmc5
gene id: 8010:psmc5
uniprot id: A0A3P8X7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8010:LOC105020699
gene id: 8010:LOC105020699
uniprot id: A0A3P9A5C0
uniprot id: A0A6Q2YF40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8010:vps18
gene id: 8010:vps18
uniprot id: A0A3P9AHF1
uniprot id: A0A3P9AHG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

8010:orc4
gene id: 8010:orc4
uniprot id: A0A3P8YDT7
uniprot id: A0A3P8YDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

8010:atpaf1
gene id: 8010:atpaf1
uniprot id: A0A3P8XA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

8010:dnajc25
gene id: 8010:dnajc25
uniprot id: A0A3P8YBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

8010:irx1a
gene id: 8010:irx1a
uniprot id: A0A3P8XD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8010:cdh19
gene id: 8010:cdh19
uniprot id: A0A3P8XWQ5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:cplx4b
gene id: 8010:cplx4b
uniprot id: A0A3P9A3T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8010:jupb
gene id: 8010:jupb
uniprot id: A0A3P9A4G8
uniprot id: A0A6Q2X431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome

8010:LOC105022964
gene id: 8010:LOC105022964
uniprot id: A0A3P8YJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8010:LOC105008256
gene id: 8010:LOC105008256
uniprot id: A0A3P9A293
uniprot id: A0A6Q2WQJ6
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

8010:tsr1
gene id: 8010:tsr1
uniprot id: A0A3P9AIJ5
names: Subcellular Location Annotation
messages: nucleolus

8010:stard5
gene id: 8010:stard5
uniprot id: A0A3P8XD27
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

8010:LOC105022133
gene id: 8010:LOC105022133
uniprot id: A0A3P8Y839
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8010:slc49a4
gene id: 8010:slc49a4
uniprot id: A0A3P8ZNT1
names: Subcellular Location Annotation
messages: Membrane

8010:traf4a
gene id: 8010:traf4a
uniprot id: A0A3P9AJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8010:ccr9a
gene id: 8010:ccr9a
uniprot id: A0A3P9AAA0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:syngr3b
gene id: 8010:syngr3b
uniprot id: A0A3P8YK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8010:acta1b
gene id: 8010:acta1b
uniprot id: A0A3P8XLX6
names: Similarity
messages: Belongs to the actin family.

8010:me1
gene id: 8010:me1
uniprot id: A0A3P9AJJ0
uniprot id: A0A6Q2X4A4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8010:si:ch211-107n13.1
gene id: 8010:si:ch211-107n13.1
uniprot id: A0A3P8YKL1
names: Similarity
messages: Belongs to the FAM110 family.

8010:lsm1
gene id: 8010:lsm1
uniprot id: A0A3P8ZDR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8010:lnpa
gene id: 8010:lnpa
uniprot id: A0A3P8Z548
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8010:erh
gene id: 8010:erh
uniprot id: C1BW66
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

8010:cpdp
gene id: 8010:cpdp
uniprot id: A0A3P8ZBM0
uniprot id: A0A3P9APF5
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

8010:nit1
gene id: 8010:nit1
uniprot id: A0A3P8ZH46
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

8010:mat2b
gene id: 8010:mat2b
uniprot id: A0A3P8Z0D8
uniprot id: A0A6Q2X0J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

8010:LOC105019163
gene id: 8010:LOC105019163
uniprot id: A0A3P8XUN9
uniprot id: A0A3P8XUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8010:LOC105015067
gene id: 8010:LOC105015067
uniprot id: A0A3P8ZES5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8010:tmem144a
gene id: 8010:tmem144a
uniprot id: A0A3P8XHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8010:rrm2b
gene id: 8010:rrm2b
uniprot id: A0A3P8YFP4
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

8010:arpc2
gene id: 8010:arpc2
uniprot id: A0A3P8Z485
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8010:ift122
gene id: 8010:ift122
uniprot id: A0A3P8YTG8
names: Subcellular Location Annotation
messages: cilium

8010:LOC105016799
gene id: 8010:LOC105016799
uniprot id: A0A3P8ZEH3
names: Similarity
messages: Belongs to the PPP1R15 family.

8010:slc26a2
gene id: 8010:slc26a2
uniprot id: A0A3P8YG49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

8010:noc4l
gene id: 8010:noc4l
uniprot id: A0A3P8Y1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

8010:b3gat2
gene id: 8010:b3gat2
uniprot id: A0A3P8Y6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105023047
gene id: 8010:LOC105023047
uniprot id: A0A3P8Z9X6
names: Similarity
messages: Belongs to the peptidase A1 family.

8010:LOC105006487
gene id: 8010:LOC105006487
uniprot id: A0A3P8ZEP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:txndc5
gene id: 8010:txndc5
uniprot id: A0A3P9AHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8010:serping1
gene id: 8010:serping1
uniprot id: A0A3P8Z6X4
names: Similarity
messages: Belongs to the serpin family.

8010:ubr2
gene id: 8010:ubr2
uniprot id: A0A3P8YKB7
uniprot id: A0A3P8YL72
uniprot id: A0A3P9A8C4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8010:htr2b
gene id: 8010:htr2b
uniprot id: A0A3P8ZIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

8010:b4galnt1a
gene id: 8010:b4galnt1a
uniprot id: A0A3P8XYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:dmrt2b
gene id: 8010:dmrt2b
uniprot id: A0A3P8Z1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8010:sntb2
gene id: 8010:sntb2
uniprot id: A0A3P8Y8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8010:LOC105026540
gene id: 8010:LOC105026540
uniprot id: A0A3P8ZVK3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:tomm20a
gene id: 8010:tomm20a
uniprot id: A0A3P8YSF2
uniprot id: A0A6Q2YMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:tagln3b
gene id: 8010:tagln3b
uniprot id: A0A3P9A505
names: Similarity
messages: Belongs to the calponin family.

8010:cep43
gene id: 8010:cep43
uniprot id: A0A3P8XZM9
uniprot id: A0A3P8Y0Z8
uniprot id: A0A3P8ZV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8010:KEF92 p08
gene id: 8010:KEF92_p08
uniprot id: Q85D54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

8010:txlnba
gene id: 8010:txlnba
uniprot id: A0A6Q2YB94
names: Similarity
messages: Belongs to the taxilin family.

8010:taf9
gene id: 8010:taf9
uniprot id: C1BXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

8010:mios
gene id: 8010:mios
uniprot id: A0A3P9A2V1
uniprot id: A0A3P9A3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

8010:tinagl1
gene id: 8010:tinagl1
uniprot id: A0A3P8XM98
names: Similarity
messages: Belongs to the peptidase C1 family.

8010:edem1
gene id: 8010:edem1
uniprot id: A0A3P8XYB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8010:mfsd5
gene id: 8010:mfsd5
uniprot id: A0A3P8ZNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8010:cpeb2
gene id: 8010:cpeb2
uniprot id: A0A3P8XJE6
uniprot id: A0A3P8XJF8
uniprot id: A0A3P8ZJM4
names: Similarity
messages: Belongs to the RRM CPEB family.

8010:pex10
gene id: 8010:pex10
uniprot id: A0A3P9A0U1
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

8010:LOC105014203
gene id: 8010:LOC105014203
uniprot id: A0A3P9ANJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8010:LOC105006531
gene id: 8010:LOC105006531
uniprot id: A0A3P8XB08
uniprot id: A0A3P8ZE92
uniprot id: A0A3P8ZFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

8010:efna3b
gene id: 8010:efna3b
uniprot id: A0A6Q2YYG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:sugct
gene id: 8010:sugct
uniprot id: A0A3P8XFP6
uniprot id: A0A3P8ZHF4
names: Similarity
messages: Belongs to the CoA-transferase III family.

8010:si:dkey-3h3.3
gene id: 8010:si:dkey-3h3.3
uniprot id: A0A3P9ALI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8010:LOC105009571
gene id: 8010:LOC105009571
uniprot id: A0A3P8XDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the noggin family.
messages: Secreted

8010:relt
gene id: 8010:relt
uniprot id: A0A3P8XZJ7
names: Similarity
messages: Belongs to the RELT family.

8010:LOC105028213
gene id: 8010:LOC105028213
uniprot id: A0A3P8YYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8010:LOC105023529
gene id: 8010:LOC105023529
uniprot id: C1BY38
names: Similarity
messages: Belongs to the UPF0729 family.

8010:wdr55
gene id: 8010:wdr55
uniprot id: A0A3P8Z2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

8010:LOC105027486
gene id: 8010:LOC105027486
uniprot id: A0A3P8Y266
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:sdhaf2
gene id: 8010:sdhaf2
uniprot id: A0A3P8XX81
uniprot id: A0A6Q2XXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

8010:abt1
gene id: 8010:abt1
uniprot id: A0A6Q2XQZ1
uniprot id: C1BYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

8010:LOC105019148
gene id: 8010:LOC105019148
uniprot id: A0A3P8Z4Y9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:cdh8
gene id: 8010:cdh8
uniprot id: A0A3P8YTW1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:sass6
gene id: 8010:sass6
uniprot id: A0A3P8ZFD7
names: Subcellular Location Annotation
messages: centrosome

8010:LOC105030252
gene id: 8010:LOC105030252
uniprot id: A0A3P8Y9Z0
uniprot id: A0A3P8YCA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

8010:vip
gene id: 8010:vip
uniprot id: A0A3P8XI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

8010:tyrp1b
gene id: 8010:tyrp1b
uniprot id: A0A3P8Y2J2
uniprot id: A0A3P8ZVH5
uniprot id: A0A3P8ZVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8010:il12rb2
gene id: 8010:il12rb2
uniprot id: A0A3P8Y4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8010:ntn2
gene id: 8010:ntn2
uniprot id: A0A3P8ZRA7
uniprot id: A0A3P8ZSK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cpb2
gene id: 8010:cpb2
uniprot id: A0A3P8Z0Q8
uniprot id: A0A3P9AI07
names: Similarity
messages: Belongs to the peptidase M14 family.

8010:supt4h1
gene id: 8010:supt4h1
uniprot id: C1BXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

8010:ube3d
gene id: 8010:ube3d
uniprot id: A0A3P9AHH1
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8010:scamp5a
gene id: 8010:scamp5a
uniprot id: A0A3P8XL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8010:naif1
gene id: 8010:naif1
uniprot id: A0A3P9AII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

8010:ap5m1
gene id: 8010:ap5m1
uniprot id: A0A3P8XW92
names: Subcellular Location Annotation
names: Subunit
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8010:prpf4bb
gene id: 8010:prpf4bb
uniprot id: A0A3P8ZI87
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

8010:pgm1
gene id: 8010:pgm1
uniprot id: A0A3P8Z3D1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8010:sept7b
gene id: 8010:sept7b
uniprot id: A0A6Q2XJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

8010:tppp3
gene id: 8010:tppp3
uniprot id: A0A3P9AAS0
names: Similarity
messages: Belongs to the TPPP family.

8010:LOC105017301
gene id: 8010:LOC105017301
uniprot id: A0A3P8ZNB6
names: Similarity
messages: Belongs to the TAFA family.

8010:il1b
gene id: 8010:il1b
uniprot id: A0A3P9AQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

8010:dpysl5a
gene id: 8010:dpysl5a
uniprot id: A0A3P9AHV1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8010:rrp7a
gene id: 8010:rrp7a
uniprot id: A0A3P8ZS69
names: Similarity
messages: Belongs to the RRP7 family.

8010:prdm8
gene id: 8010:prdm8
uniprot id: A0A3P8ZV12
names: Subcellular Location Annotation
messages: Nucleus

8010:furinb
gene id: 8010:furinb
uniprot id: A0A3P8ZH76
names: Similarity
messages: Belongs to the peptidase S8 family.

8010:fam102aa
gene id: 8010:fam102aa
uniprot id: A0A3P8X9Z3
names: Similarity
messages: Belongs to the FAM102 family.

8010:tsfm
gene id: 8010:tsfm
uniprot id: A0A3P8YG59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8010:dlc
gene id: 8010:dlc
uniprot id: A0A3P8ZYG1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8010:erbb3b
gene id: 8010:erbb3b
uniprot id: A0A3P8XW32
names: Subcellular Location Annotation
messages: Membrane

8010:pgap2
gene id: 8010:pgap2
uniprot id: A0A3P8ZU96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8010:gng3
gene id: 8010:gng3
uniprot id: A0A3P9AEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:tspo
gene id: 8010:tspo
uniprot id: C1BWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8010:tmem145
gene id: 8010:tmem145
uniprot id: A0A3P8YWJ9
names: Subcellular Location Annotation
messages: Membrane

8010:slc12a4
gene id: 8010:slc12a4
uniprot id: A0A3P8XIH4
uniprot id: A0A3P8ZK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8010:nab2
gene id: 8010:nab2
uniprot id: A0A3P8Z3V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8010:p2ry13
gene id: 8010:p2ry13
uniprot id: A0A3P8ZTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:timm22
gene id: 8010:timm22
uniprot id: C1BYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

8010:slx4
gene id: 8010:slx4
uniprot id: A0A3P9AKN6
uniprot id: A0A6Q2ZC36
names: Similarity
messages: Belongs to the SLX4 family.

8010:pigh
gene id: 8010:pigh
uniprot id: C1BXY9
names: Similarity
messages: Belongs to the PIGH family.

8010:LOC105025822
gene id: 8010:LOC105025822
uniprot id: A0A3P8YHW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

8010:smarcb1b
gene id: 8010:smarcb1b
uniprot id: A0A3P8Z0Z4
uniprot id: A0A3P9AI92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8010:papss2b
gene id: 8010:papss2b
uniprot id: A0A3P8XB86
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8010:b4galnt3b
gene id: 8010:b4galnt3b
uniprot id: A0A3P8Z1R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

8010:wnt6b
gene id: 8010:wnt6b
uniprot id: A0A3P9A4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:bida
gene id: 8010:bida
uniprot id: A0A6Q2Y7N1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

8010:tmem189
gene id: 8010:tmem189
uniprot id: A0A3P9ANC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8010:LOC105029432
gene id: 8010:LOC105029432
uniprot id: A0A3P8YNC9
uniprot id: A0A3P9A8U4
names: Similarity
messages: Belongs to the NHS family.

8010:fads6
gene id: 8010:fads6
uniprot id: A0A3P8Y4C3
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

8010:lonp2
gene id: 8010:lonp2
uniprot id: A0A3P8YFD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

8010:sec22bb
gene id: 8010:sec22bb
uniprot id: A0A3P9A4L4
uniprot id: C1BWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8010:samm50l
gene id: 8010:samm50l
uniprot id: A0A3P9ADH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

8010:LOC105022845
gene id: 8010:LOC105022845
uniprot id: A0A3P9AM03
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8010:LOC105022737
gene id: 8010:LOC105022737
uniprot id: A0A6Q2YCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8010:asah2
gene id: 8010:asah2
uniprot id: A0A3P8XAS2
names: Similarity
messages: Belongs to the neutral ceramidase family.

8010:c19h15orf40
gene id: 8010:c19h15orf40
uniprot id: A0A3P8XCR6
names: Similarity
messages: Belongs to the UPF0235 family.

8010:riox2
gene id: 8010:riox2
uniprot id: A0A3P9ADC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

8010:tlcd3ba
gene id: 8010:tlcd3ba
uniprot id: A0A3P8ZB75
names: Subcellular Location Annotation
messages: Membrane

8010:si:dkey-183j2.10
gene id: 8010:si:dkey-183j2.10
uniprot id: A0A3P8Z7Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:gnl2
gene id: 8010:gnl2
uniprot id: A0A3P9A9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8010:LOC105021141
gene id: 8010:LOC105021141
uniprot id: A0A3P9AJH0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:zdhhc9
gene id: 8010:zdhhc9
uniprot id: A0A3P8YV40
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:LOC105015299
gene id: 8010:LOC105015299
uniprot id: A0A3P8Z749
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8010:fundc1
gene id: 8010:fundc1
uniprot id: C1BYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8010:LOC105031152
gene id: 8010:LOC105031152
uniprot id: A0A3P8ZK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

8010:cdk19
gene id: 8010:cdk19
uniprot id: A0A3P9AD80
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105026337
gene id: 8010:LOC105026337
uniprot id: A0A3P9A2A0
names: Similarity
messages: Belongs to the SNF7 family.

8010:psma5
gene id: 8010:psma5
uniprot id: C1BY94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:gfra1a
gene id: 8010:gfra1a
uniprot id: A0A3P8XH05
uniprot id: A0A3P8ZJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

8010:LOC105006952
gene id: 8010:LOC105006952
uniprot id: A0A3P8Y4J7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:LOC105016703
gene id: 8010:LOC105016703
uniprot id: A0A3P8YGK9
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8010:stmn1b
gene id: 8010:stmn1b
uniprot id: A0A3P9A6F3
uniprot id: C1BXN5
names: Similarity
messages: Belongs to the stathmin family.

8010:fam219b
gene id: 8010:fam219b
uniprot id: A0A3P9A7A1
names: Similarity
messages: Belongs to the FAM219 family.

8010:laptm4b
gene id: 8010:laptm4b
uniprot id: A0A3P8YFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

8010:tmtc4
gene id: 8010:tmtc4
uniprot id: A0A3P8Y5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8010:LOC105006878
gene id: 8010:LOC105006878
uniprot id: A0A3P8YW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

8010:LOC105015510
gene id: 8010:LOC105015510
uniprot id: A0A3P8XNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8010:sec23a
gene id: 8010:sec23a
uniprot id: A0A3P8XBA5
uniprot id: A0A3P8ZER9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8010:rbl1
gene id: 8010:rbl1
uniprot id: A0A3P8ZZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8010:LOC105026199
gene id: 8010:LOC105026199
uniprot id: A0A3P8ZZW0
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

8010:lypla1
gene id: 8010:lypla1
uniprot id: A0A3P8XV67
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8010:LOC105020983
gene id: 8010:LOC105020983
uniprot id: A0A3P8YLP4
names: Similarity
messages: Belongs to the TTC39 family.

8010:pcolcea
gene id: 8010:pcolcea
uniprot id: A0A3P8YER4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:zgc:92912
gene id: 8010:zgc:92912
uniprot id: A0A3P9A9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8010:si:ch73-62b13.1
gene id: 8010:si:ch73-62b13.1
uniprot id: A0A3P9AGZ8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:tmem150c
gene id: 8010:tmem150c
uniprot id: A0A3P8XFL2
names: Subcellular Location Annotation
messages: Membrane

8010:f11r.1
gene id: 8010:f11r.1
uniprot id: A0A3P9AGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:LOC105018359
gene id: 8010:LOC105018359
uniprot id: A0A3P8XK95
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:cnih2
gene id: 8010:cnih2
uniprot id: A0A3P8YI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8010:zgc:154142
gene id: 8010:zgc:154142
uniprot id: A0A6Q2XQP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ing1
gene id: 8010:ing1
uniprot id: A0A6Q2X3I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8010:orai1b
gene id: 8010:orai1b
uniprot id: A0A3P9AI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8010:kdr
gene id: 8010:kdr
uniprot id: A0A3P8XEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:LOC105008019
gene id: 8010:LOC105008019
uniprot id: C1BW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Membrane

8010:naa40
gene id: 8010:naa40
uniprot id: A0A3P8X9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

8010:LOC105030302
gene id: 8010:LOC105030302
uniprot id: A0A3P9A7U8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:mtfp1
gene id: 8010:mtfp1
uniprot id: A0A3P9A209
names: Similarity
messages: Belongs to the MTFP1 family.

8010:ppp2r5d
gene id: 8010:ppp2r5d
uniprot id: A0A3P8YN19
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8010:aldoca
gene id: 8010:aldoca
uniprot id: A0A3P9AIT5
uniprot id: A0A6Q2XQG9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8010:LOC106024808
gene id: 8010:LOC106024808
uniprot id: A0A3P8ZFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8010:kctd13
gene id: 8010:kctd13
uniprot id: A0A3P8ZT28
names: Similarity
messages: Belongs to the BACURD family.

8010:adam9
gene id: 8010:adam9
uniprot id: A0A3P8XWL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:cart4
gene id: 8010:cart4
uniprot id: A0A3P9A8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8010:adcyap1r1b
gene id: 8010:adcyap1r1b
uniprot id: A0A3P8ZA21
names: Subcellular Location Annotation
messages: Membrane

8010:nrcama
gene id: 8010:nrcama
uniprot id: A0A3P8XX36
uniprot id: A0A3P8XX51
uniprot id: A0A3P8XXD3
uniprot id: A0A3P8Y009
uniprot id: A0A3P8ZTF8
uniprot id: A0A3P8ZUH4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8010:usp1
gene id: 8010:usp1
uniprot id: A0A3P8Z2W6
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:LOC105016715
gene id: 8010:LOC105016715
uniprot id: A0A3P9A3Z7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:tmem176
gene id: 8010:tmem176
uniprot id: C1BZT6
names: Similarity
messages: Belongs to the MS4A family.

8010:zgc:85843
gene id: 8010:zgc:85843
uniprot id: A0A3P8ZVM1
names: Subcellular Location Annotation
messages: Membrane

8010:pth4
gene id: 8010:pth4
uniprot id: A0A3P8ZGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8010:ramp2
gene id: 8010:ramp2
uniprot id: A0A3P8YV73
uniprot id: A0A3P9AF19
names: Similarity
messages: Belongs to the RAMP family.

8010:sf3a3
gene id: 8010:sf3a3
uniprot id: A0A3P8Y1B2
names: Similarity
messages: Belongs to the SF3A3 family.

8010:LOC105023556
gene id: 8010:LOC105023556
uniprot id: A0A3P8ZZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8010:rce1a
gene id: 8010:rce1a
uniprot id: A0A3P8Y612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:gkap1
gene id: 8010:gkap1
uniprot id: A0A3P8YSQ2
names: Similarity
messages: Belongs to the GKAP1 family.

8010:derl3
gene id: 8010:derl3
uniprot id: A0A3P8XB92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:lrrc32
gene id: 8010:lrrc32
uniprot id: A0A3P9AFR3
names: Similarity
messages: Belongs to the Toll-like receptor family.

8010:rrp36
gene id: 8010:rrp36
uniprot id: A0A3P9A9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

8010:llph
gene id: 8010:llph
uniprot id: C1BXE1
names: Similarity
messages: Belongs to the learning-associated protein family.

8010:clta
gene id: 8010:clta
uniprot id: A0A3P8YW32
uniprot id: A0A3P8YX29
uniprot id: A0A3P9AF22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

8010:polr2j
gene id: 8010:polr2j
uniprot id: C1BW67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

8010:wfikkn2a
gene id: 8010:wfikkn2a
uniprot id: A0A3P8ZHV5
names: Similarity
messages: Belongs to the WFIKKN family.

8010:LOC105006482
gene id: 8010:LOC105006482
uniprot id: A0A3P8ZSG1
names: Similarity
messages: Belongs to the peptidase C2 family.

8010:taf10
gene id: 8010:taf10
uniprot id: C1BY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus

8010:sec61b
gene id: 8010:sec61b
uniprot id: A0A3P8XXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

8010:gadd45ga
gene id: 8010:gadd45ga
uniprot id: C1BXC9
names: Similarity
messages: Belongs to the GADD45 family.

8010:pigg
gene id: 8010:pigg
uniprot id: A0A3P9AF43
uniprot id: A0A6Q2Z8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:mcm3
gene id: 8010:mcm3
uniprot id: A0A3P8ZRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

8010:map1lc3cl
gene id: 8010:map1lc3cl
uniprot id: A0A3P8XRW5
names: Similarity
messages: Belongs to the ATG8 family.

8010:podxl2
gene id: 8010:podxl2
uniprot id: A0A3P8YUR9
names: Subcellular Location Annotation
messages: Membrane

8010:foxh1
gene id: 8010:foxh1
uniprot id: A0A3P8YHT2
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105015860
gene id: 8010:LOC105015860
uniprot id: A0A3P8ZC62
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:tmpoa
gene id: 8010:tmpoa
uniprot id: A0A3P8Y3Y6
uniprot id: A0A3P8Y444
uniprot id: A0A3P8Y5V9
uniprot id: A0A3P8Y6M1
uniprot id: A0A3P8Y6S3
uniprot id: A0A3P8ZXE7
names: Similarity
messages: Belongs to the LEM family.

8010:flvcr2b
gene id: 8010:flvcr2b
uniprot id: A0A3P8ZHR7
names: Subcellular Location Annotation
messages: Membrane

8010:mtfmt
gene id: 8010:mtfmt
uniprot id: A0A3P8ZEI5
names: Similarity
messages: Belongs to the Fmt family.

8010:asip1
gene id: 8010:asip1
uniprot id: A0A6Q2X503
names: Subcellular Location Annotation
messages: Secreted

8010:top1l
gene id: 8010:top1l
uniprot id: A0A3P8XIT2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

8010:LOC105025772
gene id: 8010:LOC105025772
uniprot id: A0A3P8XSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8010:sema3aa
gene id: 8010:sema3aa
uniprot id: A0A3P8X9K2
uniprot id: A0A3P8ZCM0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:pnp4a
gene id: 8010:pnp4a
uniprot id: A0A3P9ALA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8010:perp
gene id: 8010:perp
uniprot id: A0A3P8YB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8010:fzd4
gene id: 8010:fzd4
uniprot id: A0A3P8ZXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8010:grm1b
gene id: 8010:grm1b
uniprot id: A0A3P9AEF2
uniprot id: A0A6Q2WSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8010:heatr1
gene id: 8010:heatr1
uniprot id: A0A3P8ZIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

8010:xylt1
gene id: 8010:xylt1
uniprot id: A0A3P8XCA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8010:LOC105020707
gene id: 8010:LOC105020707
uniprot id: A0A3P8Y8R9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8010:tac3b
gene id: 8010:tac3b
uniprot id: A0A3P8YIM9
names: Subcellular Location Annotation
messages: Secreted

8010:dmac2l
gene id: 8010:dmac2l
uniprot id: A0A3P9AGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

8010:mc2r
gene id: 8010:mc2r
uniprot id: A0A3P8XCZ9
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

8010:mmp9
gene id: 8010:mmp9
uniprot id: A0A3P9A308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

8010:bglapl
gene id: 8010:bglapl
uniprot id: A0A3P8ZE04
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

8010:LOC105019817
gene id: 8010:LOC105019817
uniprot id: A0A3P8ZLK9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8010:c9h19orf53
gene id: 8010:c9h19orf53
uniprot id: A0A3P8YJT8
names: Similarity
messages: Belongs to the UPF0390 family.

8010:ccser2a
gene id: 8010:ccser2a
uniprot id: A0A3P8ZK15
names: Similarity
messages: Belongs to the CCSER family.

8010:hopx
gene id: 8010:hopx
uniprot id: A0A3P8Z602
names: Subcellular Location Annotation
messages: Nucleus

8010:hoxd10a
gene id: 8010:hoxd10a
uniprot id: A0A3P9ALF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8010:clcn4
gene id: 8010:clcn4
uniprot id: A0A3P8YNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8010:LOC105015526
gene id: 8010:LOC105015526
uniprot id: A0A3P8XU59
names: Subcellular Location Annotation
messages: Membrane

8010:sptlc2a
gene id: 8010:sptlc2a
uniprot id: A0A3P9A8X4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8010:psmd7
gene id: 8010:psmd7
uniprot id: A0A3P8Z7R1
names: Similarity
messages: Belongs to the peptidase M67A family.

8010:fshb
gene id: 8010:fshb
uniprot id: A0A3P8Z8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

8010:LOC105013131
gene id: 8010:LOC105013131
uniprot id: A0A3P8XRF1
uniprot id: A0A3P8XV40
uniprot id: A0A3P8XV51
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8010:LOC105007241
gene id: 8010:LOC105007241
uniprot id: A0A3P8XK34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8010:ndufa2
gene id: 8010:ndufa2
uniprot id: C1BWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:si:ch73-265d7.2
gene id: 8010:si:ch73-265d7.2
uniprot id: A0A6Q2Z1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8010:actb1
gene id: 8010:actb1
uniprot id: A0A3P9A7A2
names: Similarity
messages: Belongs to the actin family.

8010:fbln1
gene id: 8010:fbln1
uniprot id: A0A3P8XR39
uniprot id: A0A3P8ZQ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:pfkfb1
gene id: 8010:pfkfb1
uniprot id: A0A3P8XL89
uniprot id: A0A3P8ZLA5
uniprot id: A0A6Q2XNC3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8010:agla
gene id: 8010:agla
uniprot id: A0A3P8XNT7
uniprot id: A0A3P8XNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

8010:tekt2
gene id: 8010:tekt2
uniprot id: A0A3P8ZBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8010:tardbp
gene id: 8010:tardbp
uniprot id: A0A3P8XYN8
names: Subcellular Location Annotation
messages: Nucleus

8010:zmynd10
gene id: 8010:zmynd10
uniprot id: A0A3P8ZKL6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: centriolar satellite

8010:vps37d
gene id: 8010:vps37d
uniprot id: A0A3P8Y955
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8010:LOC105015471
gene id: 8010:LOC105015471
uniprot id: A0A3P8ZK86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

8010:st6galnac5b
gene id: 8010:st6galnac5b
uniprot id: A0A3P8YHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:sem1
gene id: 8010:sem1
uniprot id: A0A3P8YUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

8010:tac1
gene id: 8010:tac1
uniprot id: A0A3P8XSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

8010:ifitm5
gene id: 8010:ifitm5
uniprot id: A0A3P8Z5Z2
uniprot id: A0A3P9AMW2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:LOC105024444
gene id: 8010:LOC105024444
uniprot id: A0A3P8YZJ7
uniprot id: A0A3P9AI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Postsynaptic density
messages: Synapse

8010:psmg2
gene id: 8010:psmg2
uniprot id: C1BZ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

8010:ywhah
gene id: 8010:ywhah
uniprot id: A0A3P8YRP6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8010:acbd5a
gene id: 8010:acbd5a
uniprot id: A0A3P8ZR26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

8010:camk1gb
gene id: 8010:camk1gb
uniprot id: A0A3P8XKC7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:ak4
gene id: 8010:ak4
uniprot id: A0A3P8Z4K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

8010:LOC105007422
gene id: 8010:LOC105007422
uniprot id: A0A3P8ZED2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

8010:LOC105028173
gene id: 8010:LOC105028173
uniprot id: A0A3P8XB28
uniprot id: A0A3P8XE13
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:stoml2
gene id: 8010:stoml2
uniprot id: A0A3P8YQB3
uniprot id: A0A6Q2YE69
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8010:kcnk15
gene id: 8010:kcnk15
uniprot id: A0A3P8YIA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:nf2b
gene id: 8010:nf2b
uniprot id: A0A3P8XLU9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8010:scpep1
gene id: 8010:scpep1
uniprot id: A0A3P8ZW18
names: Similarity
messages: Belongs to the peptidase S10 family.

8010:aurkb
gene id: 8010:aurkb
uniprot id: A0A3P8ZW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Chromosome

8010:pold2
gene id: 8010:pold2
uniprot id: A0A3P8XHJ7
uniprot id: A0A3P8ZFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

8010:dnajc18
gene id: 8010:dnajc18
uniprot id: A0A3P8Z4N9
names: Subcellular Location Annotation
messages: Membrane

8010:zic1
gene id: 8010:zic1
uniprot id: A0A3P8XDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8010:LOC105029498
gene id: 8010:LOC105029498
uniprot id: A0A3P8YHN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:opn4xb
gene id: 8010:opn4xb
uniprot id: A0A3P8YYB3
uniprot id: A0A3P8YZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:ei24
gene id: 8010:ei24
uniprot id: A0A3P9AQ58
uniprot id: A0A6Q2XGU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EI24 family.
messages: Membrane

8010:LOC105020133
gene id: 8010:LOC105020133
uniprot id: A0A3P8YQZ2
names: Similarity
messages: Belongs to the DENND11 family.

8010:pick1
gene id: 8010:pick1
uniprot id: A0A3P8XU69
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

8010:galnt18b
gene id: 8010:galnt18b
uniprot id: A0A3P8YGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105031638
gene id: 8010:LOC105031638
uniprot id: A0A3P8ZWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8010:si:ch211-39i2.2
gene id: 8010:si:ch211-39i2.2
uniprot id: A0A3P8ZSL3
names: Similarity
messages: Belongs to the DDIT4 family.

8010:p4ha3
gene id: 8010:p4ha3
uniprot id: A0A3P8Z5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

8010:hnrnpul1l
gene id: 8010:hnrnpul1l
uniprot id: A0A3P9ADY9
names: Subcellular Location Annotation
messages: Nucleus

8010:casc1
gene id: 8010:casc1
uniprot id: A0A3P8YS84
names: Similarity
messages: Belongs to the DNAI7 family.

8010:usp20
gene id: 8010:usp20
uniprot id: A0A3P8Z6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8010:mfn1a
gene id: 8010:mfn1a
uniprot id: A0A3P8YMC7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8010:march9
gene id: 8010:march9
uniprot id: A0A3P8XNI1
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105015488
gene id: 8010:LOC105015488
uniprot id: A0A3P8XNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8010:ube2f
gene id: 8010:ube2f
uniprot id: A0A3P8XHS9
uniprot id: A0A3P8XLR7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:prkab1b
gene id: 8010:prkab1b
uniprot id: A0A6Q2ZBK8
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8010:afmid
gene id: 8010:afmid
uniprot id: A0A3P8YRY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

8010:eno1a
gene id: 8010:eno1a
uniprot id: A0A3P8YKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8010:fdps
gene id: 8010:fdps
uniprot id: A0A3P8Y7M2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8010:LOC105010929
gene id: 8010:LOC105010929
uniprot id: A0A3P9A881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:ntng1a
gene id: 8010:ntng1a
uniprot id: A0A3P8X893
uniprot id: A0A3P8X897
uniprot id: A0A3P8X8D8
uniprot id: A0A3P8ZC22
uniprot id: A0A3P8ZD92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105020281
gene id: 8010:LOC105020281
uniprot id: A0A3P8XA57
uniprot id: A0A3P8ZE12
names: Similarity
messages: Belongs to the TEX28 family.

8010:cx55.5
gene id: 8010:cx55.5
uniprot id: A0A3P8YLU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:lmnb1
gene id: 8010:lmnb1
uniprot id: A0A3P9ADK2
names: Similarity
messages: Belongs to the intermediate filament family.

8010:eme1
gene id: 8010:eme1
uniprot id: A0A3P8Z895
names: Similarity
messages: Belongs to the EME1/MMS4 family.

8010:KEF92 p04
gene id: 8010:KEF92_p04
uniprot id: Q85D50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8010:zdhhc17
gene id: 8010:zdhhc17
uniprot id: A0A3P8Z3V3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:rpa1
gene id: 8010:rpa1
uniprot id: A0A3P8YZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

8010:grb14
gene id: 8010:grb14
uniprot id: A0A3P8YVK1
uniprot id: A0A3P9AFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8010:ociad1
gene id: 8010:ociad1
uniprot id: A0A3P8XGZ0
uniprot id: A0A3P8XJQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

8010:LOC109614642
gene id: 8010:LOC109614642
uniprot id: C1BYZ8
names: Similarity
messages: Belongs to the SH3BGR family.

8010:LOC105007542
gene id: 8010:LOC105007542
uniprot id: A0A3P9A9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:etv4
gene id: 8010:etv4
uniprot id: A0A3P8XRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:sec31a
gene id: 8010:sec31a
uniprot id: A0A3P8XB89
uniprot id: A0A3P8XE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

8010:actr3b
gene id: 8010:actr3b
uniprot id: A0A3P9A9N4
names: Similarity
messages: Belongs to the actin family.

8010:vipas39
gene id: 8010:vipas39
uniprot id: A0A3P8XNT9
uniprot id: A0A6Q2YGY3
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Vesicle

8010:plp1b
gene id: 8010:plp1b
uniprot id: A0A3P8ZPN9
uniprot id: A0A3P8ZPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8010:sumf2
gene id: 8010:sumf2
uniprot id: A0A3P8Z9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8010:itgb3a
gene id: 8010:itgb3a
uniprot id: A0A3P8YNF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8010:dzip1
gene id: 8010:dzip1
uniprot id: A0A3P8Z5G8
uniprot id: A0A3P8Z5N7
uniprot id: A0A3P8Z5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

8010:creld2
gene id: 8010:creld2
uniprot id: A0A3P8XUL4
uniprot id: A0A3P8ZSB6
uniprot id: A0A6Q2XC30
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:sema3fa
gene id: 8010:sema3fa
uniprot id: A0A3P8XWQ3
uniprot id: A0A3P8ZSF7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:epn3a
gene id: 8010:epn3a
uniprot id: A0A3P8ZYC3
names: Similarity
messages: Belongs to the epsin family.

8010:cckar
gene id: 8010:cckar
uniprot id: A0A3P8ZX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:sorcs3b
gene id: 8010:sorcs3b
uniprot id: A0A3P8XNJ2
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8010:kif18a
gene id: 8010:kif18a
uniprot id: A0A3P8ZTQ5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:gc2
gene id: 8010:gc2
uniprot id: A0A3P8Y9W8
uniprot id: A0A3P9A1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

8010:mterf2
gene id: 8010:mterf2
uniprot id: A0A3P9AG13
names: Similarity
messages: Belongs to the mTERF family.

8010:gramd1ba
gene id: 8010:gramd1ba
uniprot id: A0A3P8YXZ0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:ehd3
gene id: 8010:ehd3
uniprot id: A0A3P8Z9Z5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

8010:irx5a
gene id: 8010:irx5a
uniprot id: A0A3P8XLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8010:slc20a1a
gene id: 8010:slc20a1a
uniprot id: A0A3P9AEC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

8010:gnsa
gene id: 8010:gnsa
uniprot id: A0A3P8ZUE2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:LOC105023502
gene id: 8010:LOC105023502
uniprot id: A0A3P8XAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8010:mpp7a
gene id: 8010:mpp7a
uniprot id: A0A3P8XD88
uniprot id: A0A3P8XG47
names: Similarity
messages: Belongs to the MAGUK family.

8010:tagln3a
gene id: 8010:tagln3a
uniprot id: A0A3P8Z1I7
names: Similarity
messages: Belongs to the calponin family.

8010:nkain1
gene id: 8010:nkain1
uniprot id: A0A3P8X8N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8010:ubiad1
gene id: 8010:ubiad1
uniprot id: A0A3P8YJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

8010:ndufa5
gene id: 8010:ndufa5
uniprot id: A0A3P8YPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:shank2b
gene id: 8010:shank2b
uniprot id: A0A3P8Y0Q9
uniprot id: A0A3P8Y0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

8010:ache
gene id: 8010:ache
uniprot id: A0A3P8XZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

8010:scara5
gene id: 8010:scara5
uniprot id: A0A3P8Z5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

8010:tcp11l2
gene id: 8010:tcp11l2
uniprot id: A0A3P8X7F6
names: Similarity
messages: Belongs to the TCP11 family.

8010:LOC105011475
gene id: 8010:LOC105011475
uniprot id: C1BX69
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8010:gpr137ba
gene id: 8010:gpr137ba
uniprot id: A0A3P9ADV2
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8010:phb2a
gene id: 8010:phb2a
uniprot id: A0A3P8YM17
uniprot id: A0A3P8YM43
uniprot id: A0A6Q2ZA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8010:meig1
gene id: 8010:meig1
uniprot id: A0A3P8Y0S2
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

8010:psma6l
gene id: 8010:psma6l
uniprot id: A0A3P9AFF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:nit2
gene id: 8010:nit2
uniprot id: C1BZ04
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

8010:gpr156
gene id: 8010:gpr156
uniprot id: A0A3P8ZIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:klc2
gene id: 8010:klc2
uniprot id: A0A3P8ZJ63
uniprot id: A0A6Q2XEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8010:per1b
gene id: 8010:per1b
uniprot id: A0A3P8XZV2
uniprot id: A0A3P8ZUI2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:slc2a1b
gene id: 8010:slc2a1b
uniprot id: A0A3P8XUS0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:dkk3b
gene id: 8010:dkk3b
uniprot id: A0A3P9A6G9
names: Similarity
messages: Belongs to the dickkopf family.

8010:LOC105007755
gene id: 8010:LOC105007755
uniprot id: C1BWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8010:matk
gene id: 8010:matk
uniprot id: A0A3P8Z655
uniprot id: A0A3P8Z6G5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:lrrc8aa
gene id: 8010:lrrc8aa
uniprot id: A0A6Q2XUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8010:tvp23b
gene id: 8010:tvp23b
uniprot id: A0A3P8Y2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8010:tram1
gene id: 8010:tram1
uniprot id: A0A3P8XSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8010:fgfbp1a
gene id: 8010:fgfbp1a
uniprot id: A0A3P8ZE62
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8010:slc9a3.1
gene id: 8010:slc9a3.1
uniprot id: A0A3P8Z4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

8010:vps72a
gene id: 8010:vps72a
uniprot id: A0A3P8Y415
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

8010:dmrt3a
gene id: 8010:dmrt3a
uniprot id: A0A3P8Y197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8010:lgsn
gene id: 8010:lgsn
uniprot id: A0A3P8ZVJ2
names: Similarity
messages: Belongs to the glutamine synthetase family.

8010:rpl21
gene id: 8010:rpl21
uniprot id: A0A3P9A377
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8010:LOC105016750
gene id: 8010:LOC105016750
uniprot id: A0A3P8Y2V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:wfikkn2b
gene id: 8010:wfikkn2b
uniprot id: A0A3P9AHE0
names: Similarity
messages: Belongs to the WFIKKN family.

8010:tomm22
gene id: 8010:tomm22
uniprot id: A0A3P9AF50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

8010:cbsa
gene id: 8010:cbsa
uniprot id: A0A3P8ZYL2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

8010:med4
gene id: 8010:med4
uniprot id: C1BYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8010:ppm1la
gene id: 8010:ppm1la
uniprot id: A0A3P9AIR8
names: Similarity
messages: Belongs to the PP2C family.

8010:si:ch73-40a17.3
gene id: 8010:si:ch73-40a17.3
uniprot id: A0A3P9AEK3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:mc1r
gene id: 8010:mc1r
uniprot id: A0A3P8Y0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8010:snapc3
gene id: 8010:snapc3
uniprot id: A0A3P8YJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

8010:nol12
gene id: 8010:nol12
uniprot id: C1BWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

8010:gcshb
gene id: 8010:gcshb
uniprot id: A0A3P8YD45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8010:acsl1a
gene id: 8010:acsl1a
uniprot id: A0A3P8XFS1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8010:LOC105015707
gene id: 8010:LOC105015707
uniprot id: A0A3P8XSH2
names: Similarity
messages: Belongs to the IFT43 family.

8010:LOC105006131
gene id: 8010:LOC105006131
uniprot id: A0A3P9AKS5
uniprot id: A0A6Q2YYE4
names: Similarity
messages: Belongs to the spectrin family.

8010:LOC105009991
gene id: 8010:LOC105009991
uniprot id: C1BXA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

8010:purbb
gene id: 8010:purbb
uniprot id: A0A3P8Z9X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8010:unc5c
gene id: 8010:unc5c
uniprot id: A0A3P8Z6C5
uniprot id: A0A3P9AN22
uniprot id: A0A3P9AN33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8010:tmem53
gene id: 8010:tmem53
uniprot id: A0A3P8Y5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8010:LOC105016506
gene id: 8010:LOC105016506
uniprot id: A0A3P8XF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105012382
gene id: 8010:LOC105012382
uniprot id: A0A3P9A7Q4
names: Similarity
messages: Belongs to the FAM124 family.

8010:tomm20b
gene id: 8010:tomm20b
uniprot id: C1BZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:LOC105024419
gene id: 8010:LOC105024419
uniprot id: A0A3P9AI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

8010:LOC105008114
gene id: 8010:LOC105008114
uniprot id: A0A3P8YK44
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:LOC105005822
gene id: 8010:LOC105005822
uniprot id: A0A6Q2Y1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8010:gsx2
gene id: 8010:gsx2
uniprot id: A0A3P8XJB8
names: Subcellular Location Annotation
messages: Nucleus

8010:plpp3
gene id: 8010:plpp3
uniprot id: A0A3P8XL98
uniprot id: A0A3P8XQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8010:abcc8
gene id: 8010:abcc8
uniprot id: A0A3P9AB68
names: Subunit
messages: Interacts with KCNJ11.

8010:fam53b
gene id: 8010:fam53b
uniprot id: A0A3P9A4V6
names: Similarity
messages: Belongs to the FAM53 family.

8010:prkd4
gene id: 8010:prkd4
uniprot id: A0A3P8ZIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Membrane

8010:sae1
gene id: 8010:sae1
uniprot id: A0A3P8YPC3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8010:p3h3
gene id: 8010:p3h3
uniprot id: A0A3P8YV11
names: Similarity
messages: Belongs to the leprecan family.

8010:tmed10
gene id: 8010:tmed10
uniprot id: A0A3P8XKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:mdka
gene id: 8010:mdka
uniprot id: C1BYE0
names: Similarity
messages: Belongs to the pleiotrophin family.

8010:irak4
gene id: 8010:irak4
uniprot id: A0A3P8XYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

8010:nip7
gene id: 8010:nip7
uniprot id: A0A3P8YKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

8010:LOC105026428
gene id: 8010:LOC105026428
uniprot id: A0A3P8XPX4
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8010:park7
gene id: 8010:park7
uniprot id: C1BZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

8010:mafa
gene id: 8010:mafa
uniprot id: A0A3P8ZVG3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8010:naa25
gene id: 8010:naa25
uniprot id: A0A3P8ZE44
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

8010:jun
gene id: 8010:jun
uniprot id: A0A3P8XP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8010:haao
gene id: 8010:haao
uniprot id: A0A3P9A7P8
uniprot id: A0A6Q2WSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

8010:gabrg2
gene id: 8010:gabrg2
uniprot id: A0A3P8Z973
uniprot id: A0A3P8ZA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:syvn1
gene id: 8010:syvn1
uniprot id: A0A3P8Z2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:gcsha
gene id: 8010:gcsha
uniprot id: A0A3P8YYN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8010:hm13
gene id: 8010:hm13
uniprot id: A0A3P8Y1C6
uniprot id: A0A3P8Y1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8010:pard6gb
gene id: 8010:pard6gb
uniprot id: A0A3P8ZZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8010:clstn3
gene id: 8010:clstn3
uniprot id: A0A3P9AE11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105024560
gene id: 8010:LOC105024560
uniprot id: A0A3P8Y5N7
uniprot id: A0A3P8Y5Q8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:ntd5
gene id: 8010:ntd5
uniprot id: A0A3P8YHS4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105005790
gene id: 8010:LOC105005790
uniprot id: A0A3P9AE00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:fgg
gene id: 8010:fgg
uniprot id: A0A3P9AIB0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8010:alcama
gene id: 8010:alcama
uniprot id: A0A3P8ZMP8
uniprot id: A0A3P8ZN08
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

8010:atp13a2
gene id: 8010:atp13a2
uniprot id: A0A3P8YIV0
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

8010:ahcyl2b
gene id: 8010:ahcyl2b
uniprot id: A0A3P8YE69
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8010:ngfb
gene id: 8010:ngfb
uniprot id: A0A3P9ANU6
names: Similarity
messages: Belongs to the NGF-beta family.

8010:ppp2cab
gene id: 8010:ppp2cab
uniprot id: A0A3P8YZQ4
names: Similarity
messages: Belongs to the PPP phosphatase family.

8010:LOC105007234
gene id: 8010:LOC105007234
uniprot id: A0A3P8XWC3
names: Subcellular Location Annotation
messages: Nucleus

8010:jph1a
gene id: 8010:jph1a
uniprot id: A0A3P8ZMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8010:si:ch211-220m17.5
gene id: 8010:si:ch211-220m17.5
uniprot id: A0A3P8ZUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

8010:msx1b
gene id: 8010:msx1b
uniprot id: A0A3P8ZK37
names: Subcellular Location Annotation
messages: Nucleus

8010:si:ch211-195b15.7
gene id: 8010:si:ch211-195b15.7
uniprot id: A0A3P8ZJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8010:tmem87b
gene id: 8010:tmem87b
uniprot id: A0A3P8Y5Q5
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105028045
gene id: 8010:LOC105028045
uniprot id: A0A3P9AB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8010:mrpl49
gene id: 8010:mrpl49
uniprot id: C1BX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

8010:tomm5
gene id: 8010:tomm5
uniprot id: A0A3P9ACW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:ppa2
gene id: 8010:ppa2
uniprot id: A0A3P8YLQ0
names: Similarity
messages: Belongs to the PPase family.

8010:pknox1.1
gene id: 8010:pknox1.1
uniprot id: A0A3P8YIA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:LOC105025250
gene id: 8010:LOC105025250
uniprot id: A0A3P8Y284
uniprot id: A0A3P8ZW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8010:LOC105021564
gene id: 8010:LOC105021564
uniprot id: A0A3P8YCR3
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105012571
gene id: 8010:LOC105012571
uniprot id: A0A3P8ZP48
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:kcne4
gene id: 8010:kcne4
uniprot id: A0A3P9A501
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8010:ruvbl2
gene id: 8010:ruvbl2
uniprot id: A0A3P8XVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

8010:LOC105018046
gene id: 8010:LOC105018046
uniprot id: A0A6Q2ZL43
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:cd164
gene id: 8010:cd164
uniprot id: A0A3P8YKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

8010:LOC105022335
gene id: 8010:LOC105022335
uniprot id: A0A3P8Z7U6
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

8010:zdhhc12a
gene id: 8010:zdhhc12a
uniprot id: A0A3P8ZBE8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:LOC105017059
gene id: 8010:LOC105017059
uniprot id: A0A3P9AM86
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8010:prtfdc1b
gene id: 8010:prtfdc1b
uniprot id: A0A3P9A9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8010:LOC105019486
gene id: 8010:LOC105019486
uniprot id: A0A3P8Z5E5
uniprot id: A0A3P9ALA1
names: Subcellular Location Annotation
messages: cytoskeleton

8010:dnmt3ba
gene id: 8010:dnmt3ba
uniprot id: A0A3P8Z5V7
uniprot id: A0A3P8Z5Y9
uniprot id: A0A3P8Z6W9
uniprot id: A0A3P8Z7R6
uniprot id: A0A3P9ALP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8010:LOC105021129
gene id: 8010:LOC105021129
uniprot id: A0A3P8Z1P9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8010:naa38
gene id: 8010:naa38
uniprot id: A0A6Q2ZIP0
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

8010:LOC105020902
gene id: 8010:LOC105020902
uniprot id: A0A3P9A0J9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:dbndd1
gene id: 8010:dbndd1
uniprot id: A0A6Q2YYN9
names: Similarity
messages: Belongs to the dysbindin family.

8010:med27
gene id: 8010:med27
uniprot id: A0A3P8YJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

8010:LOC105018842
gene id: 8010:LOC105018842
uniprot id: A0A3P8XLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:tmem106bb
gene id: 8010:tmem106bb
uniprot id: A0A3P8Z816
names: Similarity
messages: Belongs to the TMEM106 family.

8010:LOC105017981
gene id: 8010:LOC105017981
uniprot id: A0A3P8XR20
uniprot id: A0A3P8ZQ02
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8010:LOC105019579
gene id: 8010:LOC105019579
uniprot id: A0A3P8YI21
names: Similarity
messages: Belongs to the RBR family.

8010:camkk1b
gene id: 8010:camkk1b
uniprot id: A0A3P8Z4V0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105018725
gene id: 8010:LOC105018725
uniprot id: A0A3P8YRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8010:armt1
gene id: 8010:armt1
uniprot id: A0A3P9A947
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

8010:fmnl1b
gene id: 8010:fmnl1b
uniprot id: A0A3P8XS13
uniprot id: A0A3P8XTC4
names: Similarity
messages: Belongs to the formin homology family.

8010:mrps30
gene id: 8010:mrps30
uniprot id: A0A3P8YDB7
names: Subcellular Location Annotation
messages: Mitochondrion

8010:pde1a
gene id: 8010:pde1a
uniprot id: A0A3P8Y243
uniprot id: A0A3P8ZUD2
uniprot id: A0A3P8ZUV0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8010:tert
gene id: 8010:tert
uniprot id: A0A3P8YGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

8010:noc2l
gene id: 8010:noc2l
uniprot id: A0A3P8XTX1
names: Similarity
messages: Belongs to the NOC2 family.

8010:LOC105023536
gene id: 8010:LOC105023536
uniprot id: C1BYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

8010:tcea3
gene id: 8010:tcea3
uniprot id: A0A3P8ZHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8010:ilf3a
gene id: 8010:ilf3a
uniprot id: A0A3P8ZA12
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:si:zfos-323e3.4
gene id: 8010:si:zfos-323e3.4
uniprot id: A0A3P8Z7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8010:bola3
gene id: 8010:bola3
uniprot id: A0A3P8YFC3
names: Similarity
messages: Belongs to the BolA/IbaG family.

8010:dync1i2a
gene id: 8010:dync1i2a
uniprot id: A0A3P8Z1K0
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8010:LOC105006661
gene id: 8010:LOC105006661
uniprot id: A0A3P8XUH1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:zgc:153675
gene id: 8010:zgc:153675
uniprot id: A0A3P8XDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

8010:pygma
gene id: 8010:pygma
uniprot id: A0A3P8Z5D2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8010:armc1
gene id: 8010:armc1
uniprot id: A0A3P9A458
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8010:LOC105025080
gene id: 8010:LOC105025080
uniprot id: A0A3P9ABC5
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

8010:atp5meb
gene id: 8010:atp5meb
uniprot id: A0A3P8XSH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

8010:pemt
gene id: 8010:pemt
uniprot id: A0A3P8XLN1
uniprot id: C1BXA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8010:pde6hb
gene id: 8010:pde6hb
uniprot id: A0A3P8XWK0
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8010:sptssb
gene id: 8010:sptssb
uniprot id: A0A3P9AP29
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105013281
gene id: 8010:LOC105013281
uniprot id: A0A3P8YGE4
names: Subcellular Location Annotation
messages: Nucleus

8010:jak2a
gene id: 8010:jak2a
uniprot id: A0A3P8XPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8010:cubn
gene id: 8010:cubn
uniprot id: A0A3P8XE81
uniprot id: A0A6Q2YVU0
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

8010:clcn3
gene id: 8010:clcn3
uniprot id: A0A3P8XF23
uniprot id: A0A3P8XF67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8010:LOC105010085
gene id: 8010:LOC105010085
uniprot id: A0A3P8ZYP6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8010:zic2a
gene id: 8010:zic2a
uniprot id: A0A3P8Y2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

8010:LOC105018861
gene id: 8010:LOC105018861
uniprot id: A0A3P8XKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8010:LOC105025818
gene id: 8010:LOC105025818
uniprot id: C1BXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8010:atp5if1b
gene id: 8010:atp5if1b
uniprot id: C1BWE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8010:kcnk12
gene id: 8010:kcnk12
uniprot id: A0A3P8ZYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:birc7
gene id: 8010:birc7
uniprot id: A0A3P8X7J9
uniprot id: A0A3P8X9V7
names: Similarity
messages: Belongs to the IAP family.

8010:xrn2
gene id: 8010:xrn2
uniprot id: A0A3P8YGQ7
uniprot id: A0A3P8YH78
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

8010:saga
gene id: 8010:saga
uniprot id: A0A3P8YL00
uniprot id: A0A3P8YL39
names: Similarity
messages: Belongs to the arrestin family.

8010:LOC105007341
gene id: 8010:LOC105007341
uniprot id: A0A3P8Z9J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:fam131a
gene id: 8010:fam131a
uniprot id: A0A3P8ZKF9
names: Similarity
messages: Belongs to the FAM131 family.

8010:npffr2a
gene id: 8010:npffr2a
uniprot id: A0A6Q2YW86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8010:drc1
gene id: 8010:drc1
uniprot id: A0A3P9ACG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

8010:ddx1
gene id: 8010:ddx1
uniprot id: A0A3P8ZLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

8010:LOC105006393
gene id: 8010:LOC105006393
uniprot id: A0A3P8YEU6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8010:LOC105030374
gene id: 8010:LOC105030374
uniprot id: A0A6Q2Z2G6
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8010:ppp1r14aa
gene id: 8010:ppp1r14aa
uniprot id: A0A3P8YNS0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8010:sfrp2
gene id: 8010:sfrp2
uniprot id: A0A3P8XDH9
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:f2
gene id: 8010:f2
uniprot id: A0A3P8Z3W8
uniprot id: A0A3P8Z4I8
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

8010:LOC105025196
gene id: 8010:LOC105025196
uniprot id: A0A3P8YVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8010:LOC105027683
gene id: 8010:LOC105027683
uniprot id: A0A3P8Z0Z8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8010:tmsb1
gene id: 8010:tmsb1
uniprot id: C1BXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

8010:dnase1l1l
gene id: 8010:dnase1l1l
uniprot id: A0A3P9A7H3
names: Similarity
messages: Belongs to the DNase I family.

8010:rogdi
gene id: 8010:rogdi
uniprot id: A0A3P8ZWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: synaptic vesicle

8010:ap1s3b
gene id: 8010:ap1s3b
uniprot id: A0A3P8Y5J8
uniprot id: A0A3P8YG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8010:dnaaf4
gene id: 8010:dnaaf4
uniprot id: A0A3P8Y624
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

8010:zgc:153284
gene id: 8010:zgc:153284
uniprot id: C1BZF1
names: Similarity
messages: Belongs to the SH3BGR family.

8010:zgc:100920
gene id: 8010:zgc:100920
uniprot id: A0A3P9AKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8010:LOC105031521
gene id: 8010:LOC105031521
uniprot id: A0A3P8ZQ33
names: Similarity
messages: Belongs to the ANP32 family.

8010:LOC105017080
gene id: 8010:LOC105017080
uniprot id: A0A3P9AKH1
names: Similarity
messages: Belongs to the neuritin family.

8010:LOC105021869
gene id: 8010:LOC105021869
uniprot id: A0A3P8YB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8010:LOC105006419
gene id: 8010:LOC105006419
uniprot id: A0A3P8ZQH8
names: Similarity
messages: Belongs to the apolipoprotein L family.

8010:LOC105029023
gene id: 8010:LOC105029023
uniprot id: A0A3P8ZAG7
names: Subcellular Location Annotation
messages: Membrane

8010:c8a
gene id: 8010:c8a
uniprot id: A0A3P8ZAG9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105025596
gene id: 8010:LOC105025596
uniprot id: A0A3P8Y7Q3
uniprot id: A0A3P8Y7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

8010:nppc
gene id: 8010:nppc
uniprot id: C1BXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8010:nr3c2
gene id: 8010:nr3c2
uniprot id: A0A3P8YBK1
names: Subcellular Location Annotation
messages: Nucleus

8010:aco1
gene id: 8010:aco1
uniprot id: A0A3P8YKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.
messages: cytosol

8010:si:ch211-71n6.4
gene id: 8010:si:ch211-71n6.4
uniprot id: A0A3P9AFZ7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8010:gnptab
gene id: 8010:gnptab
uniprot id: A0A3P8XBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

8010:pgam1b
gene id: 8010:pgam1b
uniprot id: A0A3P9AAE2
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8010:dpy30
gene id: 8010:dpy30
uniprot id: C1BWN2
names: Similarity
messages: Belongs to the dpy-30 family.

8010:fli1rs
gene id: 8010:fli1rs
uniprot id: A0A3P8YHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:slc17a7a
gene id: 8010:slc17a7a
uniprot id: A0A3P8Y8S1
names: Subcellular Location Annotation
messages: Membrane

8010:ccz1
gene id: 8010:ccz1
uniprot id: A0A3P9ABS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

8010:ankrd34c
gene id: 8010:ankrd34c
uniprot id: A0A3P8YTY4
names: Similarity
messages: Belongs to the ANKRD34 family.

8010:proza
gene id: 8010:proza
uniprot id: A0A3P8YK38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105025765
gene id: 8010:LOC105025765
uniprot id: A0A3P8XTP3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8010:atl2
gene id: 8010:atl2
uniprot id: A0A3P8XHT9
uniprot id: A0A3P8XHV3
uniprot id: A0A6Q2YRK2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8010:vps33a
gene id: 8010:vps33a
uniprot id: A0A3P8YKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8010:ist1
gene id: 8010:ist1
uniprot id: A0A3P8YPF7
uniprot id: A0A3P8YPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

8010:LOC105020363
gene id: 8010:LOC105020363
uniprot id: A0A3P8ZAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:nmbr
gene id: 8010:nmbr
uniprot id: A0A3P9AN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:gtf2a2
gene id: 8010:gtf2a2
uniprot id: C1BWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8010:nprl3
gene id: 8010:nprl3
uniprot id: A0A3P9AKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

8010:tmem150aa
gene id: 8010:tmem150aa
uniprot id: A0A3P8XIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

8010:LOC105006736
gene id: 8010:LOC105006736
uniprot id: A0A3P8XT15
uniprot id: A0A3P8ZQ31
names: Similarity
messages: Belongs to the peptidase M16 family.

8010:itm2cb
gene id: 8010:itm2cb
uniprot id: A0A3P8XQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8010:upp2
gene id: 8010:upp2
uniprot id: A0A3P9AD73
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8010:gsg1l
gene id: 8010:gsg1l
uniprot id: A0A3P9A0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8010:snx7
gene id: 8010:snx7
uniprot id: A0A3P8X953
names: Similarity
messages: Belongs to the sorting nexin family.

8010:kif21b
gene id: 8010:kif21b
uniprot id: A0A6Q2ZEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

8010:cenph
gene id: 8010:cenph
uniprot id: A0A3P8Y356
uniprot id: C1BYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

8010:LOC105005931
gene id: 8010:LOC105005931
uniprot id: A0A3P8X8T4
uniprot id: A0A3P8ZCR8
names: Subcellular Location Annotation
messages: Z line

8010:LOC105015851
gene id: 8010:LOC105015851
uniprot id: A0A3P8ZCN7
names: Similarity
messages: Belongs to the peptidase S1C family.

8010:ndufb8
gene id: 8010:ndufb8
uniprot id: C1BZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8010:atp5mc1
gene id: 8010:atp5mc1
uniprot id: C1BZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8010:nadkb
gene id: 8010:nadkb
uniprot id: A0A3P8YAF4
uniprot id: A0A3P8ZZU0
names: Similarity
messages: Belongs to the NAD kinase family.

8010:zgc:163057
gene id: 8010:zgc:163057
uniprot id: C1BYA0
names: Similarity
messages: Belongs to the globin family.

8010:LOC105007632
gene id: 8010:LOC105007632
uniprot id: A0A3P8YQG7
names: Similarity
messages: Belongs to the RRM Spen family.

8010:LOC105013041
gene id: 8010:LOC105013041
uniprot id: A0A3P9A3M2
names: Subcellular Location Annotation
messages: Membrane

8010:kif16bb
gene id: 8010:kif16bb
uniprot id: A0A3P9A137
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:cct5
gene id: 8010:cct5
uniprot id: A0A3P8X7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8010:rmi1
gene id: 8010:rmi1
uniprot id: A0A3P8ZD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8010:chl1b
gene id: 8010:chl1b
uniprot id: A0A3P8XEA2
uniprot id: A0A3P8XFQ6
uniprot id: A0A3P8XFT9
uniprot id: A0A3P8ZFW9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8010:kcnj5
gene id: 8010:kcnj5
uniprot id: A0A3P8YNC5
uniprot id: A0A3P8YNE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8010:hsd20b2
gene id: 8010:hsd20b2
uniprot id: A0A3P8XKU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:LOC105007051
gene id: 8010:LOC105007051
uniprot id: A0A3P8ZL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8010:LOC105017821
gene id: 8010:LOC105017821
uniprot id: A0A3P9A546
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8010:mmp11b
gene id: 8010:mmp11b
uniprot id: A0A3P8YZF1
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:gdi2
gene id: 8010:gdi2
uniprot id: A0A3P8ZJF7
uniprot id: A0A6Q2Z9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8010:pxmp4
gene id: 8010:pxmp4
uniprot id: A0A3P8YDI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

8010:lipf
gene id: 8010:lipf
uniprot id: A0A3P8XEC8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8010:LOC105022321
gene id: 8010:LOC105022321
uniprot id: C1BZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8010:cga
gene id: 8010:cga
uniprot id: A0A3P8YA19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

8010:trpc1
gene id: 8010:trpc1
uniprot id: A0A3P8X828
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

8010:tbl1xr1a
gene id: 8010:tbl1xr1a
uniprot id: A0A3P8XYJ2
uniprot id: A0A3P8XYP2
names: Similarity
messages: Belongs to the WD repeat EBI family.

8010:cdk18
gene id: 8010:cdk18
uniprot id: A0A3P8Y745
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:stxbp5a
gene id: 8010:stxbp5a
uniprot id: A0A3P8YIQ9
uniprot id: A0A3P8YKJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8010:LOC105012704
gene id: 8010:LOC105012704
uniprot id: A0A3P9A9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8010:LOC105029486
gene id: 8010:LOC105029486
uniprot id: A0A3P8ZSY2
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8010:LOC105012660
gene id: 8010:LOC105012660
uniprot id: A0A3P8YF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8010:LOC105020586
gene id: 8010:LOC105020586
uniprot id: A0A3P9AML0
names: Similarity
messages: Belongs to the cornifelin family.

8010:cd79b
gene id: 8010:cd79b
uniprot id: A0A3P8XKG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:LOC105026640
gene id: 8010:LOC105026640
uniprot id: A0A3P8Z0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8010:pdzk1ip1
gene id: 8010:pdzk1ip1
uniprot id: A0A6Q2ZEZ8
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105007052
gene id: 8010:LOC105007052
uniprot id: A0A3P8ZLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8010:LOC105021101
gene id: 8010:LOC105021101
uniprot id: A0A3P9A9V1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

8010:smc2
gene id: 8010:smc2
uniprot id: A0A3P8XXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

8010:LOC105029485
gene id: 8010:LOC105029485
uniprot id: A0A3P8ZSN3
uniprot id: A0A3P8ZTY5
names: Similarity
messages: Belongs to the OSBP family.

8010:prr5l
gene id: 8010:prr5l
uniprot id: A0A3P8Z651
names: Similarity
messages: Belongs to the PROTOR family.

8010:tsen15
gene id: 8010:tsen15
uniprot id: A0A3P9AN79
names: Similarity
messages: Belongs to the SEN15 family.

8010:ponzr1
gene id: 8010:ponzr1
uniprot id: C1BWP4
names: Similarity
messages: Belongs to the cornifelin family.

8010:arrb1
gene id: 8010:arrb1
uniprot id: A0A3P9AHD8
names: Similarity
messages: Belongs to the arrestin family.

8010:LOC105023112
gene id: 8010:LOC105023112
uniprot id: A0A3P8ZZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:pdlim1
gene id: 8010:pdlim1
uniprot id: A0A3P8YZK5
names: Subcellular Location Annotation
messages: Z line

8010:LOC105020367
gene id: 8010:LOC105020367
uniprot id: A0A3P9APR5
names: Similarity
messages: Belongs to the ARTD/PARP family.

8010:LOC105019393
gene id: 8010:LOC105019393
uniprot id: A0A3P8ZQD1
names: Subcellular Location Annotation
messages: Nucleus

8010:gstt2
gene id: 8010:gstt2
uniprot id: A0A3P8ZEJ7
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8010:rbp4
gene id: 8010:rbp4
uniprot id: C1BY52
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8010:rock2a
gene id: 8010:rock2a
uniprot id: A0A3P8ZQH5
uniprot id: A0A6Q2ZKC4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Homodimer.
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: centrosome

8010:pcxa
gene id: 8010:pcxa
uniprot id: A0A3P8YFJ6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

8010:LOC105028073
gene id: 8010:LOC105028073
uniprot id: A0A3P8YGL6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:rps3a
gene id: 8010:rps3a
uniprot id: C1BWY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

8010:otop1
gene id: 8010:otop1
uniprot id: A0A3P8ZW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8010:gck
gene id: 8010:gck
uniprot id: A0A3P8XD26
names: Similarity
messages: Belongs to the hexokinase family.

8010:cd40lg
gene id: 8010:cd40lg
uniprot id: A0A3P8ZGN4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8010:rsl24d1
gene id: 8010:rsl24d1
uniprot id: C1BXU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8010:LOC105030513
gene id: 8010:LOC105030513
uniprot id: A0A3P8ZNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8010:gnsb
gene id: 8010:gnsb
uniprot id: A0A3P8ZAH0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:ror2
gene id: 8010:ror2
uniprot id: A0A3P9A934
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105015764
gene id: 8010:LOC105015764
uniprot id: C1BXH5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8010:znf703
gene id: 8010:znf703
uniprot id: A0A3P8ZKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8010:flvcr1
gene id: 8010:flvcr1
uniprot id: A0A3P8ZA00
names: Subcellular Location Annotation
messages: Membrane

8010:ess2
gene id: 8010:ess2
uniprot id: A0A3P8YZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

8010:tspan11
gene id: 8010:tspan11
uniprot id: A0A3P8ZB32
uniprot id: A0A3P8ZBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:nat9
gene id: 8010:nat9
uniprot id: A0A3P8Z895
names: Similarity
messages: Belongs to the EME1/MMS4 family.

8010:ftsj3
gene id: 8010:ftsj3
uniprot id: A0A3P9A1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

8010:map3k10
gene id: 8010:map3k10
uniprot id: A0A3P9A4B7
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8010:khdrbs3
gene id: 8010:khdrbs3
uniprot id: A0A3P8Y6F2
names: Similarity
messages: Belongs to the KHDRBS family.

8010:oxa1l
gene id: 8010:oxa1l
uniprot id: A0A3P8ZCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8010:gata2a
gene id: 8010:gata2a
uniprot id: A0A3P8XQP0
names: Subcellular Location Annotation
messages: Nucleus

8010:actn2b
gene id: 8010:actn2b
uniprot id: A0A3P8ZL12
names: Similarity
messages: Belongs to the alpha-actinin family.

8010:sh3glb1a
gene id: 8010:sh3glb1a
uniprot id: A0A3P8ZD35
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

8010:ddx49
gene id: 8010:ddx49
uniprot id: A0A3P9A046
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:atp5po
gene id: 8010:atp5po
uniprot id: A0A3P8ZI83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8010:eef1b2
gene id: 8010:eef1b2
uniprot id: C1BX49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8010:cab39
gene id: 8010:cab39
uniprot id: A0A3P9A1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8010:LOC105016195
gene id: 8010:LOC105016195
uniprot id: A0A3P8ZZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8010:LOC105009118
gene id: 8010:LOC105009118
uniprot id: A0A3P8Y9L8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:LOC105015055
gene id: 8010:LOC105015055
uniprot id: A0A3P8ZG30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105024433
gene id: 8010:LOC105024433
uniprot id: A0A3P8XNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:nt5c2a
gene id: 8010:nt5c2a
uniprot id: A0A3P8YEU1
uniprot id: A0A3P9A5E0
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8010:vipr1b
gene id: 8010:vipr1b
uniprot id: A0A3P8XBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8010:LOC105026159
gene id: 8010:LOC105026159
uniprot id: A0A3P8YT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:ntrk3a
gene id: 8010:ntrk3a
uniprot id: A0A3P8Y324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:pmchl
gene id: 8010:pmchl
uniprot id: A0A3P8ZZW6
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8010:ppp2r5eb
gene id: 8010:ppp2r5eb
uniprot id: A0A3P8ZXR2
uniprot id: A0A3P8ZYL5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8010:fabp3
gene id: 8010:fabp3
uniprot id: A0A3P8X8R1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:fev
gene id: 8010:fev
uniprot id: A0A3P8YDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:meox1
gene id: 8010:meox1
uniprot id: A0A6Q2X894
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105030360
gene id: 8010:LOC105030360
uniprot id: A0A3P8XH16
names: Similarity
messages: Belongs to the CFAP97 family.

8010:mrps11
gene id: 8010:mrps11
uniprot id: C1BW94
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8010:phgdh
gene id: 8010:phgdh
uniprot id: A0A3P9AI33
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8010:nkx2.2b
gene id: 8010:nkx2.2b
uniprot id: A0A3P8YH05
names: Subcellular Location Annotation
messages: Nucleus

8010:ssr3
gene id: 8010:ssr3
uniprot id: C1BW87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8010:c16h2orf49
gene id: 8010:c16h2orf49
uniprot id: A0A3P9AHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

8010:LOC105027578
gene id: 8010:LOC105027578
uniprot id: A0A3P8YMU8
names: Similarity
messages: Belongs to the arrestin family.

8010:postnb
gene id: 8010:postnb
uniprot id: A0A3P8XLS9
names: Subcellular Location Annotation
messages: extracellular matrix

8010:cdc42ep3
gene id: 8010:cdc42ep3
uniprot id: A0A3P8YUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8010:LOC105028803
gene id: 8010:LOC105028803
uniprot id: A0A3P9AJT9
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

8010:LOC105017838
gene id: 8010:LOC105017838
uniprot id: A0A3P9A6D4
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8010:mettl1
gene id: 8010:mettl1
uniprot id: C1BXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8010:pla2g3
gene id: 8010:pla2g3
uniprot id: A0A3P8ZE90
names: Subcellular Location Annotation
messages: Secreted

8010:picalmb
gene id: 8010:picalmb
uniprot id: A0A3P9AFS0
uniprot id: A0A3P9AG36
uniprot id: A0A3P9AG58
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8010:zgc:172079
gene id: 8010:zgc:172079
uniprot id: A0A3P8ZU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8010:slc35a1
gene id: 8010:slc35a1
uniprot id: A0A3P8YKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

8010:sh3pxd2b
gene id: 8010:sh3pxd2b
uniprot id: A0A3P8Z9Q5
uniprot id: A0A3P8Z9R6
uniprot id: A0A3P9AP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

8010:e2f4
gene id: 8010:e2f4
uniprot id: A0A3P9A400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:cavin1b
gene id: 8010:cavin1b
uniprot id: A0A6Q2WU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8010:smc1b
gene id: 8010:smc1b
uniprot id: A0A3P8Y0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

8010:LOC105016299
gene id: 8010:LOC105016299
uniprot id: A0A3P8ZL92
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:LOC105012464
gene id: 8010:LOC105012464
uniprot id: A0A3P8YD41
names: Subcellular Location Annotation
messages: Membrane

8010:si:dkey-14o18.2
gene id: 8010:si:dkey-14o18.2
uniprot id: A0A3P9AJP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:polr2i
gene id: 8010:polr2i
uniprot id: A0A3P8YQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

8010:nmnat2
gene id: 8010:nmnat2
uniprot id: A0A3P8ZVU1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8010:dnajb12a
gene id: 8010:dnajb12a
uniprot id: A0A3P9APY0
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105019384
gene id: 8010:LOC105019384
uniprot id: A0A3P8Z0K6
names: Subcellular Location Annotation
messages: Membrane

8010:psmb9a
gene id: 8010:psmb9a
uniprot id: C1BY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8010:LOC105011741
gene id: 8010:LOC105011741
uniprot id: A0A6Q2ZKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

8010:apopt1
gene id: 8010:apopt1
uniprot id: C1BW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

8010:cdkn1a
gene id: 8010:cdkn1a
uniprot id: A0A3P9A2X1
uniprot id: A0A3P9A440
names: Similarity
messages: Belongs to the CDI family.

8010:tlcd5b
gene id: 8010:tlcd5b
uniprot id: A0A3P8YT52
names: Subcellular Location Annotation
messages: Membrane

8010:foxd3
gene id: 8010:foxd3
uniprot id: A0A3P8Z3D9
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105020247
gene id: 8010:LOC105020247
uniprot id: A0A3P8XCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:ascc3
gene id: 8010:ascc3
uniprot id: A0A3P8Z7K6
names: Similarity
messages: Belongs to the helicase family.

8010:hlx1
gene id: 8010:hlx1
uniprot id: A0A3P8YB37
uniprot id: A0A3P9A1V5
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105019629
gene id: 8010:LOC105019629
uniprot id: A0A3P8ZRC7
uniprot id: A0A6Q2X7S2
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105007466
gene id: 8010:LOC105007466
uniprot id: A0A3P8ZD97
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105022549
gene id: 8010:LOC105022549
uniprot id: A0A3P8YE98
uniprot id: A0A3P9A5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:cntnap1
gene id: 8010:cntnap1
uniprot id: A0A3P9AE43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

8010:LOC105019170
gene id: 8010:LOC105019170
uniprot id: A0A3P8XVA1
uniprot id: A0A3P8XVF5
uniprot id: A0A6Q2X9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton
messages: cytosol

8010:mark3a
gene id: 8010:mark3a
uniprot id: A0A3P8Y7D0
uniprot id: A0A3P8Y940
uniprot id: A0A3P8ZZT3
uniprot id: A0A3P8ZZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8010:LOC105031239
gene id: 8010:LOC105031239
uniprot id: A0A3P8ZPM6
names: Similarity
messages: Belongs to the TMEM14 family.

8010:zgc:64201
gene id: 8010:zgc:64201
uniprot id: A0A3P8XFC7
uniprot id: A0A6Q2XJQ7
names: Similarity
messages: Belongs to the PRORSD1 family.

8010:slc33a1
gene id: 8010:slc33a1
uniprot id: A0A3P8XUE9
uniprot id: A0A3P8XUG4
names: Subcellular Location Annotation
messages: Membrane

8010:barx2
gene id: 8010:barx2
uniprot id: A0A3P8YP28
names: Subcellular Location Annotation
messages: Nucleus

8010:aldoaa
gene id: 8010:aldoaa
uniprot id: A0A3P8Z6L9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8010:cog8
gene id: 8010:cog8
uniprot id: A0A3P9A6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:scrn3
gene id: 8010:scrn3
uniprot id: A0A3P8Z4K2
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8010:htr1fa
gene id: 8010:htr1fa
uniprot id: A0A3P8XUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

8010:LOC105028199
gene id: 8010:LOC105028199
uniprot id: A0A3P8Y2U1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:zdhhc23b
gene id: 8010:zdhhc23b
uniprot id: A0A3P9A280
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:ppp4cb
gene id: 8010:ppp4cb
uniprot id: A0A3P8Z309
names: Similarity
messages: Belongs to the PPP phosphatase family.

8010:sys1
gene id: 8010:sys1
uniprot id: A0A3P8Z475
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

8010:ndst1b
gene id: 8010:ndst1b
uniprot id: A0A3P8XGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8010:ppm1f
gene id: 8010:ppm1f
uniprot id: A0A3P9ALB1
names: Similarity
messages: Belongs to the PP2C family.

8010:lim2.2
gene id: 8010:lim2.2
uniprot id: A0A3P8Y9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8010:nle1
gene id: 8010:nle1
uniprot id: A0A3P9AAL9
names: Subcellular Location Annotation
messages: nucleolus

8010:LOC105019700
gene id: 8010:LOC105019700
uniprot id: A0A3P8ZAK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:allc
gene id: 8010:allc
uniprot id: A0A3P8XYZ4
names: Similarity
messages: Belongs to the allantoicase family.

8010:LOC105024400
gene id: 8010:LOC105024400
uniprot id: A0A3P8XGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:sybu
gene id: 8010:sybu
uniprot id: A0A3P8Z0Y4
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105029998
gene id: 8010:LOC105029998
uniprot id: A0A3P9A1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

8010:prmt7
gene id: 8010:prmt7
uniprot id: A0A3P8Y4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

8010:atxn7l3
gene id: 8010:atxn7l3
uniprot id: A0A3P8Z2Y5
uniprot id: A0A3P9AKS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

8010:cux2b
gene id: 8010:cux2b
uniprot id: A0A3P9AP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8010:LOC105008041
gene id: 8010:LOC105008041
uniprot id: A0A3P8XLP9
uniprot id: A0A3P8XP21
uniprot id: A0A3P8ZL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:hmx1
gene id: 8010:hmx1
uniprot id: A0A3P8XVH4
names: Subcellular Location Annotation
messages: Nucleus

8010:mst1rb
gene id: 8010:mst1rb
uniprot id: A0A3P8XE27
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:cdc25d
gene id: 8010:cdc25d
uniprot id: A0A3P9AAG5
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8010:tcirg1a
gene id: 8010:tcirg1a
uniprot id: A0A3P9AFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8010:ggh
gene id: 8010:ggh
uniprot id: A0A3P9A7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8010:fap
gene id: 8010:fap
uniprot id: A0A3P8YV71
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8010:cep57
gene id: 8010:cep57
uniprot id: A0A3P8Y0A5
names: Similarity
messages: Belongs to the translokin family.

8010:prom1a
gene id: 8010:prom1a
uniprot id: A0A3P8XF11
uniprot id: A0A3P8ZE87
uniprot id: A0A3P8ZF23
uniprot id: A0A3P8ZFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

8010:si:zfos-1056e6.1
gene id: 8010:si:zfos-1056e6.1
uniprot id: A0A3P8YG63
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:prkd2
gene id: 8010:prkd2
uniprot id: A0A3P8Y9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Membrane

8010:qrsl1
gene id: 8010:qrsl1
uniprot id: A0A3P8ZCP5
uniprot id: A0A6Q2WZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8010:mrps5
gene id: 8010:mrps5
uniprot id: A0A3P8XCH2
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

8010:zpr1
gene id: 8010:zpr1
uniprot id: A0A3P9A767
names: Similarity
messages: Belongs to the ZPR1 family.

8010:LOC105012208
gene id: 8010:LOC105012208
uniprot id: A0A3P8ZEE7
names: Similarity
messages: Belongs to the phospholipase D family.

8010:atg4da
gene id: 8010:atg4da
uniprot id: A0A3P9AMU9
uniprot id: A0A6Q2ZIK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8010:LOC105010721
gene id: 8010:LOC105010721
uniprot id: A0A3P8YTR1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8010:ell2
gene id: 8010:ell2
uniprot id: A0A3P8XZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8010:nt5c2l1
gene id: 8010:nt5c2l1
uniprot id: A0A3P8YT05
uniprot id: A0A6Q2X2I6
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8010:LOC105013211
gene id: 8010:LOC105013211
uniprot id: A0A3P9AFN3
names: Similarity
messages: Belongs to the Bcl-2 family.

8010:LOC105023309
gene id: 8010:LOC105023309
uniprot id: A0A3P9A350
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

8010:dpep2
gene id: 8010:dpep2
uniprot id: A0A3P8XM51
uniprot id: A0A3P8ZJB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8010:sept4a
gene id: 8010:sept4a
uniprot id: A0A3P8ZMF9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8010:anapc16
gene id: 8010:anapc16
uniprot id: A0A3P9A1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8010:en2b
gene id: 8010:en2b
uniprot id: A0A3P9A1S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8010:marcksa
gene id: 8010:marcksa
uniprot id: A0A6Q2X9H2
names: Similarity
messages: Belongs to the MARCKS family.

8010:ctso
gene id: 8010:ctso
uniprot id: A0A3P8YYF5
names: Similarity
messages: Belongs to the peptidase C1 family.

8010:runx1
gene id: 8010:runx1
uniprot id: A0A3P8XHK2
uniprot id: A0A3P8ZFX2
uniprot id: A0A3P8ZGR8
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105013740
gene id: 8010:LOC105013740
uniprot id: A0A3P8YXV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8010:epdl1
gene id: 8010:epdl1
uniprot id: A0A3P8Y9I2
names: Similarity
messages: Belongs to the ependymin family.

8010:lgmn
gene id: 8010:lgmn
uniprot id: A0A3P9AH53
uniprot id: A0A6Q2YYF7
names: Similarity
messages: Belongs to the peptidase C13 family.

8010:myorg
gene id: 8010:myorg
uniprot id: A0A3P8ZA86
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8010:psen1
gene id: 8010:psen1
uniprot id: A0A3P9AK36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8010:LOC105028424
gene id: 8010:LOC105028424
uniprot id: A0A3P9ALR7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105026142
gene id: 8010:LOC105026142
uniprot id: A0A3P8ZJ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:marcksl1b
gene id: 8010:marcksl1b
uniprot id: A0A3P9ACV8
names: Similarity
messages: Belongs to the MARCKS family.

8010:mrpl19
gene id: 8010:mrpl19
uniprot id: A0A3P9A7T9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8010:pmpcb
gene id: 8010:pmpcb
uniprot id: A0A3P8Z5G7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

8010:ddx59
gene id: 8010:ddx59
uniprot id: A0A3P8XL77
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

8010:LOC105021580
gene id: 8010:LOC105021580
uniprot id: A0A3P8YDR8
names: Similarity
messages: Belongs to the importin alpha family.

8010:tomm40l
gene id: 8010:tomm40l
uniprot id: A0A3P9AKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:LOC105015088
gene id: 8010:LOC105015088
uniprot id: A0A3P8YJH0
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8010:rusf1
gene id: 8010:rusf1
uniprot id: A0A3P8YWB7
names: Similarity
messages: Belongs to the RUS1 family.

8010:nagk
gene id: 8010:nagk
uniprot id: C1BZK0
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

8010:slc2a11b
gene id: 8010:slc2a11b
uniprot id: A0A3P8XBL6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:LOC105021271
gene id: 8010:LOC105021271
uniprot id: A0A3P8ZJA0
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:LOC105024647
gene id: 8010:LOC105024647
uniprot id: A0A3P8ZH93
uniprot id: A0A3P8ZH97
names: Subcellular Location Annotation
messages: Membrane

8010:map4l
gene id: 8010:map4l
uniprot id: A0A3P8YHJ4
uniprot id: A0A3P8YI14
uniprot id: A0A3P9A6A9
names: Subcellular Location Annotation
messages: cytoskeleton

8010:LOC105008560
gene id: 8010:LOC105008560
uniprot id: A0A3P8ZKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:cd9a
gene id: 8010:cd9a
uniprot id: A0A3P9AKX1
uniprot id: C1BWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8010:LOC105020531
gene id: 8010:LOC105020531
uniprot id: A0A3P8Y320
uniprot id: A0A3P8Y4U6
uniprot id: A0A3P8ZX13
names: Similarity
messages: Belongs to the PAIP2 family.

8010:cul3b
gene id: 8010:cul3b
uniprot id: A0A3P8YJ42
names: Similarity
messages: Belongs to the cullin family.

8010:LOC105006738
gene id: 8010:LOC105006738
uniprot id: A0A3P8Y0R6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:mrps17
gene id: 8010:mrps17
uniprot id: C1BWC6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8010:irx6a
gene id: 8010:irx6a
uniprot id: A0A3P8XJ87
names: Subcellular Location Annotation
messages: Nucleus

8010:suclg1
gene id: 8010:suclg1
uniprot id: A0A3P8ZGJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

8010:zgc:101583
gene id: 8010:zgc:101583
uniprot id: A0A6Q2WZ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8010:tbxas1
gene id: 8010:tbxas1
uniprot id: A0A3P9AF06
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:bbip1
gene id: 8010:bbip1
uniprot id: A0A3P8Z6S5
names: Similarity
messages: Belongs to the PDCD4 family.

8010:LOC105029697
gene id: 8010:LOC105029697
uniprot id: C1BZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:tctex1d2
gene id: 8010:tctex1d2
uniprot id: A0A3P8ZJ06
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8010:rorca
gene id: 8010:rorca
uniprot id: A0A3P9A5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8010:egfl6
gene id: 8010:egfl6
uniprot id: A0A3P8YK01
uniprot id: A0A3P9A8R3
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:chuk
gene id: 8010:chuk
uniprot id: A0A3P8XXB1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:dtymk
gene id: 8010:dtymk
uniprot id: A0A3P8ZLC1
uniprot id: C1BYB9
names: Similarity
messages: Belongs to the thymidylate kinase family.

8010:usp37
gene id: 8010:usp37
uniprot id: A0A3P8Y9G8
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:nr1d2a
gene id: 8010:nr1d2a
uniprot id: A0A3P8YBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:LOC105028202
gene id: 8010:LOC105028202
uniprot id: A0A3P8XXK3
uniprot id: A0A6Q2YAV4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:LOC105016974
gene id: 8010:LOC105016974
uniprot id: A0A3P9AHJ0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105029465
gene id: 8010:LOC105029465
uniprot id: A0A6Q2XIR6
uniprot id: C1BWG1
names: Subcellular Location Annotation
messages: Membrane

8010:si:cabz01093077.1
gene id: 8010:si:cabz01093077.1
uniprot id: A0A3P8XND6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:rpl18
gene id: 8010:rpl18
uniprot id: A0A3P9A4J8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

8010:ppp1r3b
gene id: 8010:ppp1r3b
uniprot id: A0A3P9AQ83
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

8010:rgs7bpb
gene id: 8010:rgs7bpb
uniprot id: A0A3P8Y3I7
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8010:gcgra
gene id: 8010:gcgra
uniprot id: A0A3P8XYF8
uniprot id: A0A3P8ZTU5
uniprot id: A0A6Q2WVX4
uniprot id: A0A6Q2Y0P3
names: Subcellular Location Annotation
messages: Membrane

8010:trarg1b
gene id: 8010:trarg1b
uniprot id: A0A3P8XPG9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:rbp1.1
gene id: 8010:rbp1.1
uniprot id: A0A3P8Z0S3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:pou4f2
gene id: 8010:pou4f2
uniprot id: A0A3P9A3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:pax6a
gene id: 8010:pax6a
uniprot id: A0A3P8YJR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:dnajb12b
gene id: 8010:dnajb12b
uniprot id: A0A3P9A1A1
names: Subcellular Location Annotation
messages: Membrane

8010:slc16a2
gene id: 8010:slc16a2
uniprot id: A0A3P8XJ90
uniprot id: A0A3P8XJA2
names: Subcellular Location Annotation
messages: Membrane

8010:exoc1
gene id: 8010:exoc1
uniprot id: A0A3P8XE91
uniprot id: A0A3P8ZG91
names: Similarity
messages: Belongs to the SEC3 family.

8010:vegfab
gene id: 8010:vegfab
uniprot id: A0A3P8ZIT2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8010:eif3d
gene id: 8010:eif3d
uniprot id: A0A3P8YRX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

8010:p2rx1
gene id: 8010:p2rx1
uniprot id: A0A3P8YXC4
uniprot id: A0A6Q2WSS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8010:alad
gene id: 8010:alad
uniprot id: A0A3P8Y7H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

8010:LOC105019780
gene id: 8010:LOC105019780
uniprot id: A0A3P8XGE4
uniprot id: A0A3P8ZFU5
names: Similarity
messages: Belongs to the RCAN family.

8010:LOC105028453
gene id: 8010:LOC105028453
uniprot id: A0A3P9AHY2
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

8010:LOC105023119
gene id: 8010:LOC105023119
uniprot id: A0A3P8Y7R2
uniprot id: A0A3P9A0I6
names: Similarity
messages: Belongs to the peptidase M1 family.

8010:LOC105025897
gene id: 8010:LOC105025897
uniprot id: A0A6Q2Y7B6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8010:LOC105015736
gene id: 8010:LOC105015736
uniprot id: C1BXV3
names: Subcellular Location Annotation
messages: Nucleus

8010:zgc:63972
gene id: 8010:zgc:63972
uniprot id: A0A6Q2X615
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8010:elof1
gene id: 8010:elof1
uniprot id: A0A3P9AP48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8010:hadhab
gene id: 8010:hadhab
uniprot id: A0A3P9AHI0
uniprot id: A0A6Q2ZJY0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

8010:rpl31
gene id: 8010:rpl31
uniprot id: A0A3P8XYM3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

8010:tjp3
gene id: 8010:tjp3
uniprot id: A0A3P8YZP0
names: Similarity
messages: Belongs to the MAGUK family.

8010:LOC105026027
gene id: 8010:LOC105026027
uniprot id: A0A3P8Z7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

8010:st6galnac
gene id: 8010:st6galnac
uniprot id: A0A3P8XYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:LOC105026006
gene id: 8010:LOC105026006
uniprot id: C1BWG9
names: Similarity
messages: Belongs to the calponin family.

8010:hexb
gene id: 8010:hexb
uniprot id: A0A3P8XAC0
uniprot id: A0A3P8XD85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8010:cdk14
gene id: 8010:cdk14
uniprot id: A0A3P8Z9R7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:LOC105007923
gene id: 8010:LOC105007923
uniprot id: A0A3P9AKN7
uniprot id: A0A6Q2X4F4
names: Similarity
messages: Belongs to the intermediate filament family.

8010:LOC105030261
gene id: 8010:LOC105030261
uniprot id: A0A3P8YVM4
uniprot id: A0A6Q2YTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:marco
gene id: 8010:marco
uniprot id: A0A3P8XN77
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105020703
gene id: 8010:LOC105020703
uniprot id: A0A3P8XWA1
names: Subcellular Location Annotation
messages: Nucleus

8010:itgav
gene id: 8010:itgav
uniprot id: A0A3P9A117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:pfdn1
gene id: 8010:pfdn1
uniprot id: C1BXF9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8010:igfbp3
gene id: 8010:igfbp3
uniprot id: A0A3P8X7L1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105008065
gene id: 8010:LOC105008065
uniprot id: A0A3P8YPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8010:ccdc153
gene id: 8010:ccdc153
uniprot id: A0A3P9A5X0
names: Similarity
messages: Belongs to the UPF0610 family.

8010:slc19a2
gene id: 8010:slc19a2
uniprot id: A0A3P8XAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8010:galnt9
gene id: 8010:galnt9
uniprot id: A0A3P8ZP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:gstz1
gene id: 8010:gstz1
uniprot id: A0A3P8XTK2
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

8010:foxe3
gene id: 8010:foxe3
uniprot id: A0A3P9A5N9
names: Subcellular Location Annotation
messages: Nucleus

8010:ces2b
gene id: 8010:ces2b
uniprot id: A0A3P8XF42
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8010:ptpn2b
gene id: 8010:ptpn2b
uniprot id: A0A3P8YDZ5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8010:trpc6b
gene id: 8010:trpc6b
uniprot id: A0A3P8Z8G9
uniprot id: A0A3P8Z9T6
names: Subcellular Location Annotation
messages: Membrane

8010:adam19b
gene id: 8010:adam19b
uniprot id: A0A3P8ZK74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:sypl2b
gene id: 8010:sypl2b
uniprot id: A0A3P8YJ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8010:pcsk2
gene id: 8010:pcsk2
uniprot id: A0A3P8XWL7
names: Similarity
messages: Belongs to the peptidase S8 family.

8010:scamp2l
gene id: 8010:scamp2l
uniprot id: A0A3P8Z327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8010:LOC105005863
gene id: 8010:LOC105005863
uniprot id: A0A3P8XTQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:tmem102
gene id: 8010:tmem102
uniprot id: A0A3P8Z7G2
names: Similarity
messages: Belongs to the mab-21 family.

8010:tmem88a
gene id: 8010:tmem88a
uniprot id: A0A3P8YCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

8010:lpar4
gene id: 8010:lpar4
uniprot id: A0A3P8XK00
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105012720
gene id: 8010:LOC105012720
uniprot id: A0A3P8YBD7
uniprot id: A0A6Q2YLY5
names: Similarity
messages: Belongs to the thrombospondin family.

8010:LOC105008812
gene id: 8010:LOC105008812
uniprot id: A0A3P8YYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8010:acp1
gene id: 8010:acp1
uniprot id: A0A6Q2XPE0
uniprot id: C1BYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

8010:slc26a6
gene id: 8010:slc26a6
uniprot id: A0A3P8Y3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8010:fam13c
gene id: 8010:fam13c
uniprot id: A0A3P9AAV0
names: Similarity
messages: Belongs to the FAM13 family.

8010:glula
gene id: 8010:glula
uniprot id: A0A3P8YKI3
names: Similarity
messages: Belongs to the glutamine synthetase family.

8010:e2f5
gene id: 8010:e2f5
uniprot id: A0A3P8Z2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:qpctla
gene id: 8010:qpctla
uniprot id: A0A3P8YC98
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8010:LOC105031580
gene id: 8010:LOC105031580
uniprot id: A0A6Q2X484
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8010:wfikkn1
gene id: 8010:wfikkn1
uniprot id: A0A3P8ZEM7
names: Similarity
messages: Belongs to the WFIKKN family.

8010:LOC105028835
gene id: 8010:LOC105028835
uniprot id: A0A3P9ALF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8010:smfn
gene id: 8010:smfn
uniprot id: A0A3P8YXH9
names: Similarity
messages: Belongs to the oligoribonuclease family.

8010:LOC105025336
gene id: 8010:LOC105025336
uniprot id: A0A3P8YWR2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:ywhae1
gene id: 8010:ywhae1
uniprot id: A0A3P8Y2I4
uniprot id: A0A3P8Y3R5
uniprot id: A0A3P8ZVL9
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8010:cdc45
gene id: 8010:cdc45
uniprot id: A0A3P8XVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

8010:LOC105012214
gene id: 8010:LOC105012214
uniprot id: A0A3P8ZEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

8010:gins1
gene id: 8010:gins1
uniprot id: A0A3P9A9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8010:st8sia3
gene id: 8010:st8sia3
uniprot id: A0A3P8YH43
uniprot id: A0A3P9A574
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8010:LOC105016240
gene id: 8010:LOC105016240
uniprot id: A0A3P8ZHN3
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8010:rnmt
gene id: 8010:rnmt
uniprot id: A0A3P9A4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

8010:cpt2
gene id: 8010:cpt2
uniprot id: A0A3P8Z9G9
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8010:itih2
gene id: 8010:itih2
uniprot id: A0A3P8ZL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8010:hkdc1
gene id: 8010:hkdc1
uniprot id: A0A3P9AD72
names: Similarity
messages: Belongs to the hexokinase family.

8010:piwil2
gene id: 8010:piwil2
uniprot id: A0A3P8XTX2
names: Similarity
messages: Belongs to the argonaute family.

8010:si:ch211-216b21.2
gene id: 8010:si:ch211-216b21.2
uniprot id: A0A3P8YJZ9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:dph6
gene id: 8010:dph6
uniprot id: A0A3P8ZMI7
uniprot id: A0A3P8ZN72
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

8010:rcl1
gene id: 8010:rcl1
uniprot id: C1BXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

8010:cspg4
gene id: 8010:cspg4
uniprot id: A0A3P8X6W6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:adprm
gene id: 8010:adprm
uniprot id: A0A3P9AJC3
names: Similarity
names: Subunit
messages: Belongs to the ADPRibase-Mn family.
messages: Monomer.

8010:lhfpl5a
gene id: 8010:lhfpl5a
uniprot id: A0A3P9AEU0
names: Subcellular Location Annotation
messages: Membrane

8010:gstp1
gene id: 8010:gstp1
uniprot id: C1BZ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

8010:ano6
gene id: 8010:ano6
uniprot id: A0A3P8X7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8010:LOC105021082
gene id: 8010:LOC105021082
uniprot id: A0A3P8YUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

8010:fbxl5
gene id: 8010:fbxl5
uniprot id: A0A3P8XMQ5
names: Subcellular Location Annotation
messages: perinuclear region

8010:mmp25a
gene id: 8010:mmp25a
uniprot id: A0A3P8ZKR3
names: Similarity
messages: Belongs to the peptidase M10A family.

8010:LOC105022217
gene id: 8010:LOC105022217
uniprot id: A0A3P9AGZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8010:znf706
gene id: 8010:znf706
uniprot id: A0A3P8YEK3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:ydjc
gene id: 8010:ydjc
uniprot id: A0A3P8Z3R8
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

8010:elk4
gene id: 8010:elk4
uniprot id: A0A3P8Y7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:oprl1
gene id: 8010:oprl1
uniprot id: A0A3P8YQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

8010:dpf2
gene id: 8010:dpf2
uniprot id: A0A3P8YLG8
names: Similarity
messages: Belongs to the requiem/DPF family.

8010:vps26a
gene id: 8010:vps26a
uniprot id: C1BYP3
names: Similarity
messages: Belongs to the VPS26 family.

8010:alox12
gene id: 8010:alox12
uniprot id: A0A3P8Y2V7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:sf3b5
gene id: 8010:sf3b5
uniprot id: C1BXH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8010:usp2a
gene id: 8010:usp2a
uniprot id: A0A3P8Y1Z3
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:vamp2
gene id: 8010:vamp2
uniprot id: A0A3P8YET3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane

8010:oxtr
gene id: 8010:oxtr
uniprot id: A0A3P9AC18
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105022483
gene id: 8010:LOC105022483
uniprot id: A0A3P9AJ44
names: Similarity
messages: Belongs to the GORASP family.

8010:rps6kb1b
gene id: 8010:rps6kb1b
uniprot id: A0A3P8YV78
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8010:dr1
gene id: 8010:dr1
uniprot id: A0A3P8ZDT4
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

8010:supt3h
gene id: 8010:supt3h
uniprot id: A0A3P9A1E0
names: Subcellular Location Annotation
messages: Nucleus

8010:calb2a
gene id: 8010:calb2a
uniprot id: A0A3P8YP27
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

8010:ipo4
gene id: 8010:ipo4
uniprot id: A0A3P9AGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

8010:nanos1
gene id: 8010:nanos1
uniprot id: A0A3P9AKN9
names: Similarity
messages: Belongs to the nanos family.

8010:LOC105016230
gene id: 8010:LOC105016230
uniprot id: A0A3P9AMI2
names: Subcellular Location Annotation
messages: Nucleus

8010:abcg8
gene id: 8010:abcg8
uniprot id: A0A3P9A162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8010:LOC105020288
gene id: 8010:LOC105020288
uniprot id: A0A3P8ZDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

8010:dtx3
gene id: 8010:dtx3
uniprot id: A0A3P8XZX7
uniprot id: A0A3P8Y1K2
uniprot id: A0A3P8ZW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8010:tmod1
gene id: 8010:tmod1
uniprot id: A0A3P8YVA8
uniprot id: A0A3P9AEV6
names: Subcellular Location Annotation
messages: cytoskeleton

8010:ankrd13a
gene id: 8010:ankrd13a
uniprot id: A0A3P8XA43
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8010:cdkn2aip
gene id: 8010:cdkn2aip
uniprot id: A0A3P8XA00
names: Similarity
messages: Belongs to the CARF family.

8010:lmod3
gene id: 8010:lmod3
uniprot id: A0A3P8YXS1
names: Subcellular Location Annotation
messages: cytoskeleton

8010:si:busm1-52i16.2
gene id: 8010:si:busm1-52i16.2
uniprot id: A0A3P9AMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8010:snx2
gene id: 8010:snx2
uniprot id: A0A3P8XPK5
uniprot id: A0A3P8XTA9
uniprot id: A0A3P8ZN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

8010:rnft2
gene id: 8010:rnft2
uniprot id: A0A3P8XEJ8
names: Subcellular Location Annotation
messages: Membrane

8010:dda1
gene id: 8010:dda1
uniprot id: A0A6Q2ZCG1
names: Similarity
messages: Belongs to the DDA1 family.

8010:ptges3l
gene id: 8010:ptges3l
uniprot id: C1BXL1
names: Similarity
messages: Belongs to the p23/wos2 family.

8010:LOC105026338
gene id: 8010:LOC105026338
uniprot id: A0A3P8YBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

8010:amd1
gene id: 8010:amd1
uniprot id: A0A3P9ABU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

8010:LOC105026122
gene id: 8010:LOC105026122
uniprot id: A0A3P9ALV3
names: Similarity
messages: Belongs to the cyclin family.

8010:LOC105010914
gene id: 8010:LOC105010914
uniprot id: A0A3P9A8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:rpia
gene id: 8010:rpia
uniprot id: A0A3P8ZB45
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

8010:eif4a1b
gene id: 8010:eif4a1b
uniprot id: A0A3P8ZU68
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

8010:LOC105030354
gene id: 8010:LOC105030354
uniprot id: C1BYD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8010:LOC105031141
gene id: 8010:LOC105031141
uniprot id: A0A3P8XMR1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8010:scp2a
gene id: 8010:scp2a
uniprot id: A0A3P9A0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Mitochondrion
messages: Peroxisome

8010:gpib
gene id: 8010:gpib
uniprot id: A0A3P8ZMC5
names: Similarity
messages: Belongs to the GPI family.

8010:LOC105021879
gene id: 8010:LOC105021879
uniprot id: A0A3P8YAG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8010:pdrg1
gene id: 8010:pdrg1
uniprot id: C1BY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

8010:LOC105028768
gene id: 8010:LOC105028768
uniprot id: A0A3P9AP23
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:ell
gene id: 8010:ell
uniprot id: A0A3P8YP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8010:camk4
gene id: 8010:camk4
uniprot id: A0A3P8ZGQ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:cnn2
gene id: 8010:cnn2
uniprot id: A0A3P8YX80
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8010:chata
gene id: 8010:chata
uniprot id: A0A3P8YAF9
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8010:LOC105011359
gene id: 8010:LOC105011359
uniprot id: A0A3P8ZGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8010:tm9sf2
gene id: 8010:tm9sf2
uniprot id: A0A3P8ZCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8010:atp6v0a1a
gene id: 8010:atp6v0a1a
uniprot id: A0A3P8YSS1
uniprot id: A0A3P8YTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8010:ube2na
gene id: 8010:ube2na
uniprot id: A0A6Q2YJZ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:psmd8
gene id: 8010:psmd8
uniprot id: A0A3P9AK56
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

8010:LOC105012565
gene id: 8010:LOC105012565
uniprot id: A0A3P8ZPH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8010:LOC105021085
gene id: 8010:LOC105021085
uniprot id: A0A3P8XQX0
uniprot id: A0A3P8ZQ51
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:gpia
gene id: 8010:gpia
uniprot id: A0A3P9AA96
names: Similarity
messages: Belongs to the GPI family.

8010:mblac1
gene id: 8010:mblac1
uniprot id: A0A3P8Y1L9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8010:eif2s1b
gene id: 8010:eif2s1b
uniprot id: A0A3P8ZQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

8010:LOC105012171
gene id: 8010:LOC105012171
uniprot id: A0A3P9AQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8010:notum1b
gene id: 8010:notum1b
uniprot id: A0A3P9AD66
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8010:zgc:172271
gene id: 8010:zgc:172271
uniprot id: A0A3P8X8B5
uniprot id: A0A3P8X8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8010:mpp6a
gene id: 8010:mpp6a
uniprot id: A0A3P8XAE7
names: Similarity
messages: Belongs to the MAGUK family.

8010:prrt1b
gene id: 8010:prrt1b
uniprot id: A0A3P8XA02
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:LOC105024398
gene id: 8010:LOC105024398
uniprot id: A0A3P8XJA1
uniprot id: A0A3P8ZJ76
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8010:thop1
gene id: 8010:thop1
uniprot id: A0A3P8XDC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8010:LOC105018272
gene id: 8010:LOC105018272
uniprot id: A0A3P8Y150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8010:ctsf
gene id: 8010:ctsf
uniprot id: A0A3P8XX16
names: Similarity
messages: Belongs to the peptidase C1 family.

8010:LOC105019035
gene id: 8010:LOC105019035
uniprot id: A0A3P8YIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8010:LOC105019404
gene id: 8010:LOC105019404
uniprot id: A0A3P8XFB0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:sh3bp5la
gene id: 8010:sh3bp5la
uniprot id: A0A3P8YGQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8010:satb2
gene id: 8010:satb2
uniprot id: A0A3P8XMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8010:traf3
gene id: 8010:traf3
uniprot id: A0A3P8XHK3
uniprot id: A0A6Q2Y625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8010:use1
gene id: 8010:use1
uniprot id: A0A3P9ADE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:tsg101a
gene id: 8010:tsg101a
uniprot id: A0A3P8Z4S6
uniprot id: A0A3P8Z5N4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

8010:LOC105024411
gene id: 8010:LOC105024411
uniprot id: A0A3P8YZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

8010:tlr3
gene id: 8010:tlr3
uniprot id: A0A3P9AIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:sypl2a
gene id: 8010:sypl2a
uniprot id: C1BYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8010:valopa
gene id: 8010:valopa
uniprot id: A0A3P9AC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8010:cx39.4
gene id: 8010:cx39.4
uniprot id: A0A3P8YIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:shtn3
gene id: 8010:shtn3
uniprot id: A0A3P9AKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8010:olfm3a
gene id: 8010:olfm3a
uniprot id: A0A3P8ZCB6
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8010:pex1
gene id: 8010:pex1
uniprot id: A0A3P8Z035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

8010:tubb2b
gene id: 8010:tubb2b
uniprot id: A0A3P8ZBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8010:bysl
gene id: 8010:bysl
uniprot id: A0A3P8YC32
names: Similarity
messages: Belongs to the bystin family.

8010:gria1a
gene id: 8010:gria1a
uniprot id: A0A3P8XK31
uniprot id: A0A3P8ZKH1
names: Subcellular Location Annotation
messages: Membrane

8010:rxrgb
gene id: 8010:rxrgb
uniprot id: A0A3P8Y3I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8010:hmox
gene id: 8010:hmox
uniprot id: C1BXT4
names: Similarity
messages: Belongs to the heme oxygenase family.

8010:armc1l
gene id: 8010:armc1l
uniprot id: A0A3P8ZL73
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8010:hoxc6a
gene id: 8010:hoxc6a
uniprot id: A0A3P8XTD4
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105022076
gene id: 8010:LOC105022076
uniprot id: A0A3P9AHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8010:cart1
gene id: 8010:cart1
uniprot id: A0A3P8ZGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8010:isoc2
gene id: 8010:isoc2
uniprot id: A0A3P9A6R1
names: Similarity
messages: Belongs to the isochorismatase family.

8010:grin1b
gene id: 8010:grin1b
uniprot id: A0A3P8ZRX5
uniprot id: A0A3P8ZSL8
uniprot id: A0A3P8ZT36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:dpcd
gene id: 8010:dpcd
uniprot id: C1BZG9
names: Similarity
messages: Belongs to the DPCD family.

8010:LOC105010677
gene id: 8010:LOC105010677
uniprot id: A0A3P8ZRN1
uniprot id: A0A6Q2WWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8010:bco2l
gene id: 8010:bco2l
uniprot id: A0A3P8ZBV1
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

8010:snap91a
gene id: 8010:snap91a
uniprot id: A0A3P8Z0Y7
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8010:LOC105017613
gene id: 8010:LOC105017613
uniprot id: A0A3P8XIS7
uniprot id: A0A3P8ZHL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8010:tspy
gene id: 8010:tspy
uniprot id: A0A3P8Z1H0
uniprot id: A0A3P9AJT2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8010:LOC105008543
gene id: 8010:LOC105008543
uniprot id: A0A3P9A466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

8010:LOC105021698
gene id: 8010:LOC105021698
uniprot id: A0A3P9A872
names: Similarity
messages: Belongs to the globin family.

8010:dhrs11a
gene id: 8010:dhrs11a
uniprot id: A0A3P8Z235
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:gbe1b
gene id: 8010:gbe1b
uniprot id: A0A3P9AQK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

8010:polr1h
gene id: 8010:polr1h
uniprot id: A0A3P8YP92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

8010:kifc1
gene id: 8010:kifc1
uniprot id: A0A3P9AH02
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:LOC105025512
gene id: 8010:LOC105025512
uniprot id: A0A3P8YLV1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:serpinh1a
gene id: 8010:serpinh1a
uniprot id: A0A3P8XLA5
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8010:LOC105023722
gene id: 8010:LOC105023722
uniprot id: A0A3P8Z3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:katnb1
gene id: 8010:katnb1
uniprot id: A0A3P8ZK09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

8010:LOC105010112
gene id: 8010:LOC105010112
uniprot id: C1BYK4
names: Similarity
messages: Belongs to the globin family.

8010:ppfibp2b
gene id: 8010:ppfibp2b
uniprot id: A0A3P8YJL7
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8010:dgkb
gene id: 8010:dgkb
uniprot id: A0A3P8YFU6
uniprot id: A0A3P8YGA2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8010:adora2aa
gene id: 8010:adora2aa
uniprot id: A0A3P8X7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8010:ufc1
gene id: 8010:ufc1
uniprot id: C1BZU2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

8010:znf277
gene id: 8010:znf277
uniprot id: A0A3P8YLH9
names: Similarity
messages: Belongs to the ZNF277 family.

8010:rell1
gene id: 8010:rell1
uniprot id: A0A3P8ZVT8
names: Similarity
messages: Belongs to the RELT family.

8010:dars2
gene id: 8010:dars2
uniprot id: A0A3P8Y0I5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

8010:LOC105023954
gene id: 8010:LOC105023954
uniprot id: A0A3P8XJR9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:lbx2
gene id: 8010:lbx2
uniprot id: A0A3P8Z2Y0
names: Subcellular Location Annotation
messages: Nucleus

8010:lias
gene id: 8010:lias
uniprot id: A0A6Q2Y6Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

8010:adam17b
gene id: 8010:adam17b
uniprot id: A0A3P9A384
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:arhgef9a
gene id: 8010:arhgef9a
uniprot id: A0A3P8Y1U9
uniprot id: A0A3P8ZV92
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

8010:copz1
gene id: 8010:copz1
uniprot id: C1BY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8010:ruvbl1
gene id: 8010:ruvbl1
uniprot id: A0A3P9A8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

8010:nexmif
gene id: 8010:nexmif
uniprot id: A0A3P8XSK3
names: Subcellular Location Annotation
messages: Nucleus

8010:ube2e2
gene id: 8010:ube2e2
uniprot id: C1BY82
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:LOC105025784
gene id: 8010:LOC105025784
uniprot id: A0A3P8ZQ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

8010:pla2g12a
gene id: 8010:pla2g12a
uniprot id: A0A6Q2WRM8
names: Subcellular Location Annotation
messages: Secreted

8010:rpl28
gene id: 8010:rpl28
uniprot id: A0A3P8X747
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

8010:LOC105017115
gene id: 8010:LOC105017115
uniprot id: A0A3P8YB65
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

8010:ripor1
gene id: 8010:ripor1
uniprot id: A0A3P8YKT8
uniprot id: A0A3P8YKW8
names: Similarity
messages: Belongs to the RIPOR family.

8010:LOC105026677
gene id: 8010:LOC105026677
uniprot id: A0A3P8XG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

8010:cfap97
gene id: 8010:cfap97
uniprot id: A0A3P8XG76
names: Similarity
messages: Belongs to the CFAP97 family.

8010:zfpm2a
gene id: 8010:zfpm2a
uniprot id: A0A3P8ZK22
names: Subcellular Location Annotation
messages: Nucleus

8010:mthfd1l
gene id: 8010:mthfd1l
uniprot id: A0A3P9AAF5
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

8010:rps16
gene id: 8010:rps16
uniprot id: C1BYC1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8010:LOC105021088
gene id: 8010:LOC105021088
uniprot id: A0A3P9AE02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8010:LOC105026904
gene id: 8010:LOC105026904
uniprot id: A0A6Q2XHL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:vegfd
gene id: 8010:vegfd
uniprot id: A0A3P8Y6D6
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8010:LOC105030754
gene id: 8010:LOC105030754
uniprot id: A0A3P9AFH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:si:dkey-71l1.1
gene id: 8010:si:dkey-71l1.1
uniprot id: A0A3P8Y213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:tyro3
gene id: 8010:tyro3
uniprot id: A0A3P8X9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8010:gig2o
gene id: 8010:gig2o
uniprot id: A0A3P9A9U7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8010:aqp8a.1
gene id: 8010:aqp8a.1
uniprot id: A0A3P8YSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8010:tmed9
gene id: 8010:tmed9
uniprot id: C1BZA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:slc25a27
gene id: 8010:slc25a27
uniprot id: A0A3P8XFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:kcnc3b
gene id: 8010:kcnc3b
uniprot id: A0A3P8XT93
uniprot id: A0A3P8ZN11
uniprot id: A0A3P8ZN28
uniprot id: A0A3P8ZNK6
names: Subcellular Location Annotation
messages: Membrane

8010:uggt2
gene id: 8010:uggt2
uniprot id: A0A3P8XFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

8010:sgsm3
gene id: 8010:sgsm3
uniprot id: A0A3P8ZHC4
uniprot id: A0A3P8ZHY0
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

8010:pnrc1
gene id: 8010:pnrc1
uniprot id: A0A6Q2YVD3
names: Subcellular Location Annotation
messages: Nucleus

8010:ihha
gene id: 8010:ihha
uniprot id: A0A3P9A203
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8010:slc5a11
gene id: 8010:slc5a11
uniprot id: A0A3P8ZLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8010:LOC105016995
gene id: 8010:LOC105016995
uniprot id: A0A3P8YXN0
uniprot id: A0A3P8YXN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8010:LOC105012257
gene id: 8010:LOC105012257
uniprot id: A0A3P8XMG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:mapk8a
gene id: 8010:mapk8a
uniprot id: A0A3P8XZ47
uniprot id: A0A3P8ZUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8010:hyal2a
gene id: 8010:hyal2a
uniprot id: A0A3P8XRN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8010:LOC105009611
gene id: 8010:LOC105009611
uniprot id: A0A3P8ZT56
names: Similarity
messages: Belongs to the globin family.

8010:LOC105007826
gene id: 8010:LOC105007826
uniprot id: A0A3P9AI98
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

8010:lamc2
gene id: 8010:lamc2
uniprot id: A0A3P8Y159
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8010:LOC105016832
gene id: 8010:LOC105016832
uniprot id: C1BYD7
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

8010:pop7
gene id: 8010:pop7
uniprot id: A0A3P8Z920
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

8010:LOC105008555
gene id: 8010:LOC105008555
uniprot id: A0A3P8XIC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

8010:LOC105024654
gene id: 8010:LOC105024654
uniprot id: A0A3P8XIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:fut7
gene id: 8010:fut7
uniprot id: A0A3P8X9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8010:ddx3xa
gene id: 8010:ddx3xa
uniprot id: A0A3P9AND2
uniprot id: A0A6Q2XN62
names: Similarity
messages: Belongs to the DEAD box helicase family.

8010:hyal1
gene id: 8010:hyal1
uniprot id: A0A3P8ZNA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8010:LOC105026099
gene id: 8010:LOC105026099
uniprot id: A0A3P8YJ92
names: Similarity
messages: Belongs to the BCL7 family.

8010:cnot6l
gene id: 8010:cnot6l
uniprot id: A0A3P8Y9C3
uniprot id: A0A6Q2Y9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105012099
gene id: 8010:LOC105012099
uniprot id: A0A3P8Z477
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8010:LOC105023713
gene id: 8010:LOC105023713
uniprot id: A0A3P8Z2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8010:grin3bb
gene id: 8010:grin3bb
uniprot id: A0A3P9A267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8010:phpt1
gene id: 8010:phpt1
uniprot id: C1BY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

8010:ndufs1
gene id: 8010:ndufs1
uniprot id: A0A3P8X7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8010:lhpp
gene id: 8010:lhpp
uniprot id: A0A3P8YFC9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8010:mks1
gene id: 8010:mks1
uniprot id: A0A3P8YBZ7
names: Subcellular Location Annotation
messages: cilium basal body

8010:thg1l
gene id: 8010:thg1l
uniprot id: C1BYC0
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

8010:nae1
gene id: 8010:nae1
uniprot id: A0A3P8XXK9
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

8010:tmem151ba
gene id: 8010:tmem151ba
uniprot id: A0A3P9A193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8010:c24h11orf68
gene id: 8010:c24h11orf68
uniprot id: A0A3P9A1R7
names: Similarity
messages: Belongs to the UPF0696 family.

8010:itga1
gene id: 8010:itga1
uniprot id: A0A3P8XK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:ormdl2
gene id: 8010:ormdl2
uniprot id: C1BWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8010:tecrb
gene id: 8010:tecrb
uniprot id: A0A3P8YCV8
uniprot id: A0A3P9A424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:mrpl16
gene id: 8010:mrpl16
uniprot id: A0A3P8ZDA7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8010:LOC105008816
gene id: 8010:LOC105008816
uniprot id: A0A3P8XTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8010:LOC105027024
gene id: 8010:LOC105027024
uniprot id: A0A3P9AI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8010:LOC105031602
gene id: 8010:LOC105031602
uniprot id: A0A3P8Y8Z5
uniprot id: A0A6Q2Y004
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:LOC105023155
gene id: 8010:LOC105023155
uniprot id: A0A3P8ZC90
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:smc5
gene id: 8010:smc5
uniprot id: A0A3P9A014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

8010:LOC105028426
gene id: 8010:LOC105028426
uniprot id: A0A3P8Z4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8010:snrpa1
gene id: 8010:snrpa1
uniprot id: A0A3P8Z910
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

8010:xkr5a
gene id: 8010:xkr5a
uniprot id: A0A3P8YJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8010:smarca1
gene id: 8010:smarca1
uniprot id: A0A3P8XZW1
uniprot id: A0A3P8XZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

8010:gtf2h2
gene id: 8010:gtf2h2
uniprot id: A0A3P8ZP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

8010:pkig
gene id: 8010:pkig
uniprot id: C1BXL6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8010:gtf2ird1
gene id: 8010:gtf2ird1
uniprot id: A0A3P8YVK9
names: Subcellular Location Annotation
messages: Nucleus

8010:cript
gene id: 8010:cript
uniprot id: C1BZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

8010:serf2
gene id: 8010:serf2
uniprot id: C1BX53
names: Similarity
messages: Belongs to the SERF family.

8010:slc25a24l
gene id: 8010:slc25a24l
uniprot id: A0A3P8XRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8010:mitfa
gene id: 8010:mitfa
uniprot id: A0A3P8ZFG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8010:dusp16
gene id: 8010:dusp16
uniprot id: A0A3P8XXM9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8010:hus1
gene id: 8010:hus1
uniprot id: A0A3P8YK30
names: Similarity
messages: Belongs to the HUS1 family.

8010:chdh
gene id: 8010:chdh
uniprot id: A0A3P8Y5L4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

8010:LOC105014946
gene id: 8010:LOC105014946
uniprot id: A0A3P8ZDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8010:camsap2a
gene id: 8010:camsap2a
uniprot id: A0A3P8XL09
uniprot id: A0A3P8XL19
uniprot id: A0A3P8ZIV6
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8010:spire2
gene id: 8010:spire2
uniprot id: A0A3P8Y8F0
uniprot id: A0A3P8ZZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8010:ago3b
gene id: 8010:ago3b
uniprot id: A0A3P8X786
uniprot id: A0A6Q2YVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

8010:c17h6orf89
gene id: 8010:c17h6orf89
uniprot id: A0A3P8XCU7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8010:si:ch211-30b16.2
gene id: 8010:si:ch211-30b16.2
uniprot id: A0A3P8ZUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:zc3hc1
gene id: 8010:zc3hc1
uniprot id: A0A3P9AM09
names: Subcellular Location Annotation
messages: Nucleus

8010:cltcl1
gene id: 8010:cltcl1
uniprot id: A0A3P8ZT29
uniprot id: A0A3P8ZT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8010:LOC105018616
gene id: 8010:LOC105018616
uniprot id: A0A6Q2Z2K4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105017826
gene id: 8010:LOC105017826
uniprot id: A0A3P9A5F9
names: Subcellular Location Annotation
messages: Nucleus

8010:glsa
gene id: 8010:glsa
uniprot id: A0A3P9A7T5
names: Similarity
messages: Belongs to the glutaminase family.

8010:lmnb2
gene id: 8010:lmnb2
uniprot id: A0A3P8ZXM3
names: Similarity
messages: Belongs to the intermediate filament family.

8010:vldlr
gene id: 8010:vldlr
uniprot id: A0A3P8X8A3
uniprot id: A0A6Q2Y064
uniprot id: A0A6Q2YKA2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: clathrin-coated pit

8010:anapc5
gene id: 8010:anapc5
uniprot id: A0A3P8Z5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

8010:s100z
gene id: 8010:s100z
uniprot id: A0A3P8XNB3
names: Similarity
messages: Belongs to the S-100 family.

8010:acsf2
gene id: 8010:acsf2
uniprot id: A0A3P8XYE6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:LOC105016321
gene id: 8010:LOC105016321
uniprot id: A0A3P8ZRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8010:ggps1
gene id: 8010:ggps1
uniprot id: A0A3P9ABJ5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8010:ap1g2
gene id: 8010:ap1g2
uniprot id: A0A3P8XFP5
uniprot id: A0A3P8XIJ9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8010:cinp
gene id: 8010:cinp
uniprot id: A0A3P8ZHB3
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8010:LOC105030120
gene id: 8010:LOC105030120
uniprot id: A0A3P8ZM76
names: Subcellular Location Annotation
messages: Membrane

8010:sdhb
gene id: 8010:sdhb
uniprot id: A0A3P9A130
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8010:LOC105012287
gene id: 8010:LOC105012287
uniprot id: A0A3P8ZKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

8010:ube2b
gene id: 8010:ube2b
uniprot id: C1BWA9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:LOC105028802
gene id: 8010:LOC105028802
uniprot id: A0A3P8Z504
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

8010:akt3a
gene id: 8010:akt3a
uniprot id: A0A3P8Y9H7
uniprot id: A0A3P8Y9Q5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8010:notum2
gene id: 8010:notum2
uniprot id: A0A3P8ZF45
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8010:slc27a6
gene id: 8010:slc27a6
uniprot id: A0A3P8YJ68
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:fut9a
gene id: 8010:fut9a
uniprot id: A0A3P9AFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8010:tdp1
gene id: 8010:tdp1
uniprot id: A0A3P8YPF4
uniprot id: A0A6Q2YCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

8010:si:ch211-156l18.8
gene id: 8010:si:ch211-156l18.8
uniprot id: A0A3P8XYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8010:LOC105005669
gene id: 8010:LOC105005669
uniprot id: A0A3P8XEK0
names: Similarity
messages: Belongs to the cornifelin family.

8010:pappa2
gene id: 8010:pappa2
uniprot id: A0A3P8Y104
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ptger4b
gene id: 8010:ptger4b
uniprot id: A0A3P8ZGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8010:syndig1l
gene id: 8010:syndig1l
uniprot id: A0A3P8YYL6
uniprot id: A0A3P8YYQ2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8010:gch1
gene id: 8010:gch1
uniprot id: A0A3P8YGR4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8010:LOC105005599
gene id: 8010:LOC105005599
uniprot id: A0A3P8ZTG8
names: Similarity
messages: Belongs to the SH2B adapter family.

8010:pitx2
gene id: 8010:pitx2
uniprot id: A0A3P8Z0X3
uniprot id: A0A3P9AHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8010:efnb1
gene id: 8010:efnb1
uniprot id: A0A6Q2WXX8
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:kcnv2a
gene id: 8010:kcnv2a
uniprot id: A0A3P8ZC68
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105014907
gene id: 8010:LOC105014907
uniprot id: A0A3P8Z2C6
uniprot id: A0A3P9AJ88
names: Similarity
messages: Belongs to the BACURD family.

8010:LOC105028200
gene id: 8010:LOC105028200
uniprot id: A0A3P8Y4D9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:csnk1da
gene id: 8010:csnk1da
uniprot id: A0A3P8ZX48
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:afap1l1b
gene id: 8010:afap1l1b
uniprot id: A0A3P8Z4L0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

8010:atg2b
gene id: 8010:atg2b
uniprot id: A0A6Q2X4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8010:hspd1
gene id: 8010:hspd1
uniprot id: A0A3P8ZJT1
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8010:itga2b
gene id: 8010:itga2b
uniprot id: A0A3P8Y5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8010:eaf1
gene id: 8010:eaf1
uniprot id: A0A3P8XYB6
names: Similarity
messages: Belongs to the EAF family.

8010:hoxb2a
gene id: 8010:hoxb2a
uniprot id: A0A3P9A500
names: Subcellular Location Annotation
messages: Nucleus

8010:nox1
gene id: 8010:nox1
uniprot id: A0A3P8ZHD0
names: Subcellular Location Annotation
messages: Membrane

8010:acss1
gene id: 8010:acss1
uniprot id: A0A3P9AAM4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8010:LOC105024424
gene id: 8010:LOC105024424
uniprot id: A0A3P8ZJD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8010:rimkla
gene id: 8010:rimkla
uniprot id: A0A3P8ZNI9
names: Similarity
messages: Belongs to the RimK family.

8010:ileu
gene id: 8010:ileu
uniprot id: C1BXP1
names: Similarity
messages: Belongs to the serpin family.

8010:pif1
gene id: 8010:pif1
uniprot id: A0A3P8YW61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

8010:rgmb
gene id: 8010:rgmb
uniprot id: A0A3P8Y4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

8010:ccdc65
gene id: 8010:ccdc65
uniprot id: A0A3P8YJS9
uniprot id: A0A3P8YKI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

8010:LOC105030729
gene id: 8010:LOC105030729
uniprot id: A0A3P8XQD5
uniprot id: A0A3P8ZN94
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8010:LOC105021374
gene id: 8010:LOC105021374
uniprot id: A0A3P9AIF3
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105029945
gene id: 8010:LOC105029945
uniprot id: A0A3P8XVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:slc25a47a
gene id: 8010:slc25a47a
uniprot id: A0A3P8ZXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:magt1
gene id: 8010:magt1
uniprot id: C1BXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105022933
gene id: 8010:LOC105022933
uniprot id: A0A3P8YRC9
names: Subcellular Location Annotation
messages: Nucleus

8010:vhll
gene id: 8010:vhll
uniprot id: A0A6Q2YGT2
names: Similarity
messages: Belongs to the VHL family.

8010:LOC105028206
gene id: 8010:LOC105028206
uniprot id: A0A3P8XYU6
names: Similarity
messages: Belongs to the copine family.

8010:eps8l3a
gene id: 8010:eps8l3a
uniprot id: A0A3P9A425
names: Similarity
messages: Belongs to the EPS8 family.

8010:elavl4
gene id: 8010:elavl4
uniprot id: A0A3P8XRP0
uniprot id: A0A3P8XU10
uniprot id: A0A3P8XU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

8010:LOC105017375
gene id: 8010:LOC105017375
uniprot id: C1BY89
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:nop16
gene id: 8010:nop16
uniprot id: A0A6Q2ZKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

8010:LOC105008840
gene id: 8010:LOC105008840
uniprot id: A0A3P9AAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8010:LOC105006836
gene id: 8010:LOC105006836
uniprot id: A0A3P8ZLX2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

8010:LOC105015986
gene id: 8010:LOC105015986
uniprot id: A0A3P8ZWW6
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

8010:wee2
gene id: 8010:wee2
uniprot id: A0A3P9ABU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

8010:fabp4a
gene id: 8010:fabp4a
uniprot id: C1BW31
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:tmem168a
gene id: 8010:tmem168a
uniprot id: A0A3P8YBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

8010:clul1
gene id: 8010:clul1
uniprot id: A0A3P8Y480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8010:pik3cg
gene id: 8010:pik3cg
uniprot id: A0A3P8YMV3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8010:LOC105031443
gene id: 8010:LOC105031443
uniprot id: A0A3P8ZAK2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:LOC105011813
gene id: 8010:LOC105011813
uniprot id: A0A3P9A3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8010:tbxtb
gene id: 8010:tbxtb
uniprot id: A0A3P8YG02
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:nhsl2
gene id: 8010:nhsl2
uniprot id: A0A3P8YA49
uniprot id: A0A3P8YBN1
uniprot id: A0A3P8YCC7
uniprot id: A0A3P9A281
uniprot id: A0A3P9A2B4
names: Similarity
messages: Belongs to the NHS family.

8010:lmod1b
gene id: 8010:lmod1b
uniprot id: A0A3P8Z4Z8
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

8010:impa1
gene id: 8010:impa1
uniprot id: A0A3P8XME1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8010:rnpc3
gene id: 8010:rnpc3
uniprot id: A0A3P8X8H1
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105020449
gene id: 8010:LOC105020449
uniprot id: A0A3P8XR45
uniprot id: A0A3P8XRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8010:gabrb4
gene id: 8010:gabrb4
uniprot id: A0A3P8YEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:enpp4
gene id: 8010:enpp4
uniprot id: A0A3P8YAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

8010:agxtb
gene id: 8010:agxtb
uniprot id: A0A3P9AK30
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8010:zdhhc6
gene id: 8010:zdhhc6
uniprot id: A0A3P8XIU3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:cth
gene id: 8010:cth
uniprot id: A0A3P8Z9H4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

8010:tmem98
gene id: 8010:tmem98
uniprot id: A0A3P8YIH1
uniprot id: A0A3P8YKI6
uniprot id: A0A3P9A7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

8010:pin4
gene id: 8010:pin4
uniprot id: C1BXI8
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

8010:tmem19
gene id: 8010:tmem19
uniprot id: A0A3P9A0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8010:atp9b
gene id: 8010:atp9b
uniprot id: A0A3P8ZSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8010:cd151
gene id: 8010:cd151
uniprot id: A0A3P9ANW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:cnot7
gene id: 8010:cnot7
uniprot id: A0A3P8ZU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8010:KEF92 p05
gene id: 8010:KEF92_p05
uniprot id: Q85D51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8010:slc16a12b
gene id: 8010:slc16a12b
uniprot id: A0A3P8XC86
names: Subcellular Location Annotation
messages: Membrane

8010:inka2
gene id: 8010:inka2
uniprot id: A0A3P9AJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8010:anxa6
gene id: 8010:anxa6
uniprot id: A0A3P8Z1I9
uniprot id: A0A3P8Z1N7
uniprot id: A0A3P8Z2B6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8010:LOC105022637
gene id: 8010:LOC105022637
uniprot id: A0A3P8YBJ9
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105028414
gene id: 8010:LOC105028414
uniprot id: A0A3P8ZW80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8010:anxa13l
gene id: 8010:anxa13l
uniprot id: A0A3P9A845
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8010:sumo1
gene id: 8010:sumo1
uniprot id: A0A3P8YU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8010:hsd17b4
gene id: 8010:hsd17b4
uniprot id: A0A3P8YVY2
names: Subcellular Location Annotation
messages: Peroxisome

8010:treh
gene id: 8010:treh
uniprot id: A0A3P9AM39
uniprot id: A0A6Q2Z0T9
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

8010:rdh1
gene id: 8010:rdh1
uniprot id: A0A3P9AH51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:tspan33a
gene id: 8010:tspan33a
uniprot id: A0A3P8Z7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:LOC105014044
gene id: 8010:LOC105014044
uniprot id: C1BZ78
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

8010:ska1
gene id: 8010:ska1
uniprot id: A0A3P8YT86
names: Similarity
messages: Belongs to the SKA1 family.

8010:fmnl1a
gene id: 8010:fmnl1a
uniprot id: A0A3P8YWG3
names: Similarity
messages: Belongs to the formin homology family.

8010:cacng8b
gene id: 8010:cacng8b
uniprot id: A0A3P9A5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8010:LOC105007952
gene id: 8010:LOC105007952
uniprot id: A0A3P9A6F7
uniprot id: A0A3P9A6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:hook1
gene id: 8010:hook1
uniprot id: A0A3P8ZXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

8010:vsx1
gene id: 8010:vsx1
uniprot id: A0A3P8YMX5
names: Subcellular Location Annotation
messages: Nucleus

8010:fam20b
gene id: 8010:fam20b
uniprot id: A0A3P8XRK4
names: Similarity
messages: Belongs to the FAM20 family.

8010:kcnk18
gene id: 8010:kcnk18
uniprot id: A0A3P8YBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:LOC105023774
gene id: 8010:LOC105023774
uniprot id: A0A3P8YCU8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8010:LOC105017118
gene id: 8010:LOC105017118
uniprot id: A0A6Q2YDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8010:stk17b
gene id: 8010:stk17b
uniprot id: A0A3P8XVN9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:zgc:153441
gene id: 8010:zgc:153441
uniprot id: A0A3P8YKM0
uniprot id: A0A3P9A7S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:tmx2b
gene id: 8010:tmx2b
uniprot id: A0A3P9AH05
uniprot id: A0A6Q2XGX1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8010:si:ch211-26b3.4
gene id: 8010:si:ch211-26b3.4
uniprot id: A0A3P8XYN2
uniprot id: A0A3P8ZUE0
names: Similarity
messages: Belongs to the CNKSR family.

8010:aldh4a1
gene id: 8010:aldh4a1
uniprot id: A0A3P8Y1J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:cds1
gene id: 8010:cds1
uniprot id: A0A3P9ANE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8010:dym
gene id: 8010:dym
uniprot id: A0A3P8XWX8
names: Similarity
messages: Belongs to the dymeclin family.

8010:LOC105016655
gene id: 8010:LOC105016655
uniprot id: A0A3P8YMP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8010:gcgb
gene id: 8010:gcgb
uniprot id: A0A3P9AFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8010:LOC105024761
gene id: 8010:LOC105024761
uniprot id: A0A3P8Z777
uniprot id: A0A3P9AMD9
uniprot id: A0A3P9ANJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105021446
gene id: 8010:LOC105021446
uniprot id: A0A3P8XGM3
names: Subcellular Location Annotation
messages: Membrane

8010:tut4
gene id: 8010:tut4
uniprot id: A0A3P8ZB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

8010:LOC105021390
gene id: 8010:LOC105021390
uniprot id: A0A3P8Z1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8010:stom
gene id: 8010:stom
uniprot id: A0A3P9A878
uniprot id: A0A6Q2Z3R9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8010:mapre3a
gene id: 8010:mapre3a
uniprot id: A0A3P8YYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8010:LOC105026491
gene id: 8010:LOC105026491
uniprot id: A0A3P9AE16
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8010:myca
gene id: 8010:myca
uniprot id: A0A3P8XSJ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

8010:idi1
gene id: 8010:idi1
uniprot id: A0A3P8ZFH0
uniprot id: C1BZP7
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

8010:snu13a
gene id: 8010:snu13a
uniprot id: C1BWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8010:adra2b
gene id: 8010:adra2b
uniprot id: A0A3P8ZQ95
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:ost4
gene id: 8010:ost4
uniprot id: A0A3P8ZPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:ldhd
gene id: 8010:ldhd
uniprot id: A0A3P8Y2G5
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

8010:psmd11b
gene id: 8010:psmd11b
uniprot id: A0A3P8ZPP4
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

8010:zranb2
gene id: 8010:zranb2
uniprot id: A0A3P9A0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

8010:psd3l
gene id: 8010:psd3l
uniprot id: A0A3P8YND5
names: Subcellular Location Annotation
messages: ruffle membrane

8010:glulb
gene id: 8010:glulb
uniprot id: A0A3P8X9B4
names: Similarity
messages: Belongs to the glutamine synthetase family.

8010:sult2st2
gene id: 8010:sult2st2
uniprot id: C1BZC2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:fzd3a
gene id: 8010:fzd3a
uniprot id: A0A3P8ZVR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:pou4f3
gene id: 8010:pou4f3
uniprot id: A0A3P8Z6B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:notch2
gene id: 8010:notch2
uniprot id: A0A3P8YFL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8010:erlin1
gene id: 8010:erlin1
uniprot id: A0A3P8ZS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

8010:faxcb
gene id: 8010:faxcb
uniprot id: A0A3P9AK09
names: Similarity
messages: Belongs to the FAX family.

8010:aptx
gene id: 8010:aptx
uniprot id: A0A6Q2YRE1
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

8010:si:ch211-57i17.1
gene id: 8010:si:ch211-57i17.1
uniprot id: A0A3P8XGU6
uniprot id: A0A3P8ZJF9
names: Similarity
messages: Belongs to the zygin family.

8010:LOC105030224
gene id: 8010:LOC105030224
uniprot id: A0A3P8Y8R3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

8010:LOC105006886
gene id: 8010:LOC105006886
uniprot id: A0A3P9A5K0
names: Subcellular Location Annotation
messages: Membrane

8010:si:dkey-178e17.1
gene id: 8010:si:dkey-178e17.1
uniprot id: A0A3P8ZTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:LOC105023682
gene id: 8010:LOC105023682
uniprot id: A0A3P8Z2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:gcgrb
gene id: 8010:gcgrb
uniprot id: A0A6Q2X3S1
names: Subcellular Location Annotation
messages: Membrane

8010:wrnip1
gene id: 8010:wrnip1
uniprot id: A0A3P8YVI5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

8010:c7a
gene id: 8010:c7a
uniprot id: A0A3P8ZDK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105006024
gene id: 8010:LOC105006024
uniprot id: A0A3P8ZWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:slc66a1
gene id: 8010:slc66a1
uniprot id: A0A3P9A4T4
uniprot id: C1BYL7
names: Subcellular Location Annotation
messages: Membrane

8010:ext2
gene id: 8010:ext2
uniprot id: A0A3P8XZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8010:mdh1ab
gene id: 8010:mdh1ab
uniprot id: A0A3P9A202
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8010:LOC105018945
gene id: 8010:LOC105018945
uniprot id: A0A3P8ZR22
uniprot id: A0A6Q2YS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8010:atp6v0b
gene id: 8010:atp6v0b
uniprot id: A0A3P8Y4H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

8010:LOC105021109
gene id: 8010:LOC105021109
uniprot id: A0A3P8YLJ2
uniprot id: A0A6Q2XXK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8010:plxnb2b
gene id: 8010:plxnb2b
uniprot id: A0A6Q2XRZ4
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:mdfi
gene id: 8010:mdfi
uniprot id: A0A3P8Y6G1
names: Similarity
messages: Belongs to the MDFI family.

8010:ndufs7
gene id: 8010:ndufs7
uniprot id: A0A3P8XZF0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

8010:tmod4
gene id: 8010:tmod4
uniprot id: A0A3P8Y1M6
uniprot id: C1BXA0
names: Subcellular Location Annotation
messages: cytoskeleton

8010:l3mbtl2
gene id: 8010:l3mbtl2
uniprot id: A0A3P8YW71
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

8010:strn3
gene id: 8010:strn3
uniprot id: A0A3P8ZFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8010:cebpd
gene id: 8010:cebpd
uniprot id: A0A3P8Z3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

8010:snx9a
gene id: 8010:snx9a
uniprot id: A0A3P8YS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8010:ercc4
gene id: 8010:ercc4
uniprot id: A0A3P8YT75
uniprot id: A0A6Q2WXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

8010:cenpv
gene id: 8010:cenpv
uniprot id: A0A3P9AJP0
names: Similarity
messages: Belongs to the Gfa family.

8010:clic2
gene id: 8010:clic2
uniprot id: A0A3P8YXI7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8010:mrpl37
gene id: 8010:mrpl37
uniprot id: A0A3P9AP15
names: Subcellular Location Annotation
messages: Mitochondrion

8010:utp15
gene id: 8010:utp15
uniprot id: A0A3P8ZHS2
uniprot id: A0A6Q2X094
names: Subcellular Location Annotation
messages: nucleolus

8010:hgh1
gene id: 8010:hgh1
uniprot id: A0A3P9AKP0
names: Similarity
messages: Belongs to the HGH1 family.

8010:LOC105016209
gene id: 8010:LOC105016209
uniprot id: A0A3P8Z4E4
uniprot id: A0A3P8Z5B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8010:LOC105031203
gene id: 8010:LOC105031203
uniprot id: A0A3P8XGY8
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8010:entr1
gene id: 8010:entr1
uniprot id: A0A3P8XBN7
names: Similarity
messages: Belongs to the ENTR1 family.

8010:gsr
gene id: 8010:gsr
uniprot id: A0A3P8YSX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

8010:zcchc8
gene id: 8010:zcchc8
uniprot id: A0A3P8YIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

8010:abi3a
gene id: 8010:abi3a
uniprot id: A0A3P8YCC4
uniprot id: A0A3P8YCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8010:smarcb1a
gene id: 8010:smarcb1a
uniprot id: A0A3P8X7K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8010:ncaph2
gene id: 8010:ncaph2
uniprot id: A0A3P8ZPL0
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

8010:pdgfd
gene id: 8010:pdgfd
uniprot id: A0A3P8Y6H8
names: Caution
names: Subunit
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:smim19
gene id: 8010:smim19
uniprot id: A0A3P8ZCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

8010:panx2
gene id: 8010:panx2
uniprot id: A0A3P8YYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8010:ppil3
gene id: 8010:ppil3
uniprot id: C1BXN0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8010:zgc:162331
gene id: 8010:zgc:162331
uniprot id: A0A3P9A903
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105031442
gene id: 8010:LOC105031442
uniprot id: A0A3P9AQB8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:polr2eb
gene id: 8010:polr2eb
uniprot id: C1BWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8010:LOC105018216
gene id: 8010:LOC105018216
uniprot id: A0A3P9A2A1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:LOC105013726
gene id: 8010:LOC105013726
uniprot id: A0A3P8YWU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8010:LOC105015825
gene id: 8010:LOC105015825
uniprot id: A0A3P8XC53
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105017138
gene id: 8010:LOC105017138
uniprot id: A0A3P8YDC4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

8010:maml1
gene id: 8010:maml1
uniprot id: A0A3P9AJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8010:LOC105005984
gene id: 8010:LOC105005984
uniprot id: A0A3P9AED7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8010:zmp:0000000846
gene id: 8010:zmp:0000000846
uniprot id: A0A3P8XUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

8010:hoxa1a
gene id: 8010:hoxa1a
uniprot id: A0A3P8XGP2
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105013091
gene id: 8010:LOC105013091
uniprot id: A0A3P9ALD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8010:ltk
gene id: 8010:ltk
uniprot id: A0A3P8ZDH6
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:rpl35
gene id: 8010:rpl35
uniprot id: C1BWT5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8010:pax6b
gene id: 8010:pax6b
uniprot id: A0A3P8Z636
uniprot id: A0A3P8Z736
uniprot id: A0A3P9AN06
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:dph3
gene id: 8010:dph3
uniprot id: C1BWV7
names: Similarity
messages: Belongs to the DPH3 family.

8010:LOC105020219
gene id: 8010:LOC105020219
uniprot id: A0A3P8XMZ1
names: Subcellular Location Annotation
messages: Nucleus

8010:dnmt1
gene id: 8010:dnmt1
uniprot id: A0A3P9ANX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8010:nf2a
gene id: 8010:nf2a
uniprot id: A0A3P8ZG60
uniprot id: A0A6Q2ZBF7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8010:LOC105021010
gene id: 8010:LOC105021010
uniprot id: A0A3P8Y9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8010:LOC105016459
gene id: 8010:LOC105016459
uniprot id: A0A3P8ZM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8010:LOC105026644
gene id: 8010:LOC105026644
uniprot id: A0A6Q2XHD3
names: Subcellular Location Annotation
messages: Nucleus

8010:dlx6a
gene id: 8010:dlx6a
uniprot id: A0A3P8YUE7
names: Subcellular Location Annotation
messages: Nucleus

8010:camk2a
gene id: 8010:camk2a
uniprot id: A0A3P8XDH2
uniprot id: A0A3P8XHR4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8010:drd2l
gene id: 8010:drd2l
uniprot id: A0A3P9A6U0
uniprot id: A0A3P9A856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105010774
gene id: 8010:LOC105010774
uniprot id: A0A3P8ZZT7
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105009204
gene id: 8010:LOC105009204
uniprot id: A0A3P9A316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:foxe1
gene id: 8010:foxe1
uniprot id: A0A6Q2XSB8
names: Subcellular Location Annotation
messages: Nucleus

8010:acer1
gene id: 8010:acer1
uniprot id: A0A3P9A2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

8010:phf10
gene id: 8010:phf10
uniprot id: A0A3P8YEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

8010:pah
gene id: 8010:pah
uniprot id: A0A3P8ZEA9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8010:slc5a3b
gene id: 8010:slc5a3b
uniprot id: A0A3P8XGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8010:eif2b5
gene id: 8010:eif2b5
uniprot id: A0A3P8YIP6
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

8010:s1pr4
gene id: 8010:s1pr4
uniprot id: A0A3P8Z843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:nsmce1
gene id: 8010:nsmce1
uniprot id: A0A3P8YZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

8010:rtn2b
gene id: 8010:rtn2b
uniprot id: A0A3P8ZTJ0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:pafah1b1a
gene id: 8010:pafah1b1a
uniprot id: A0A3P8XRI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

8010:spock2
gene id: 8010:spock2
uniprot id: A0A3P9AP04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:psmg1
gene id: 8010:psmg1
uniprot id: C1BX00
names: Similarity
messages: Belongs to the PSMG1 family.

8010:tcta
gene id: 8010:tcta
uniprot id: A0A3P9AML4
names: Similarity
messages: Belongs to the TCTA family.

8010:imp3
gene id: 8010:imp3
uniprot id: A0A3P8Z6R0
uniprot id: A0A6Q2X4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8010:cdkn1bb
gene id: 8010:cdkn1bb
uniprot id: A0A3P8ZQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

8010:nkd1
gene id: 8010:nkd1
uniprot id: A0A3P8XLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8010:dis3l
gene id: 8010:dis3l
uniprot id: A0A3P8YU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

8010:slc35b1
gene id: 8010:slc35b1
uniprot id: A0A3P8YYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8010:rpl22
gene id: 8010:rpl22
uniprot id: C1BY03
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8010:LOC105018412
gene id: 8010:LOC105018412
uniprot id: A0A3P8ZFL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8010:si:ch1073-396h14.1
gene id: 8010:si:ch1073-396h14.1
uniprot id: A0A3P9AKM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ctsh
gene id: 8010:ctsh
uniprot id: A0A3P9ADI7
names: Similarity
messages: Belongs to the peptidase C1 family.

8010:engase
gene id: 8010:engase
uniprot id: A0A3P8Y294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

8010:mark1
gene id: 8010:mark1
uniprot id: A0A3P8YLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8010:LOC105017173
gene id: 8010:LOC105017173
uniprot id: A0A3P9AB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

8010:fam199x
gene id: 8010:fam199x
uniprot id: A0A3P8YBP1
names: Similarity
messages: Belongs to the FAM199 family.

8010:LOC105018343
gene id: 8010:LOC105018343
uniprot id: A0A3P8YCQ9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:trappc6bl
gene id: 8010:trappc6bl
uniprot id: C1BXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8010:coq2
gene id: 8010:coq2
uniprot id: A0A3P8YE57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

8010:cntnap2b
gene id: 8010:cntnap2b
uniprot id: A0A3P8YCI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

8010:pgap3
gene id: 8010:pgap3
uniprot id: A0A3P8Z7K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:jph3
gene id: 8010:jph3
uniprot id: A0A3P8ZUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8010:sptssa
gene id: 8010:sptssa
uniprot id: C1BXF7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105020622
gene id: 8010:LOC105020622
uniprot id: A0A3P9AAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8010:LOC105007687
gene id: 8010:LOC105007687
uniprot id: A0A3P8Z0U5
names: Subcellular Location Annotation
messages: Membrane

8010:yy1b
gene id: 8010:yy1b
uniprot id: A0A3P8ZYK0
names: Similarity
messages: Belongs to the YY transcription factor family.

8010:slc29a1a
gene id: 8010:slc29a1a
uniprot id: A0A3P8XDS8
uniprot id: A0A3P8XI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8010:inka1b
gene id: 8010:inka1b
uniprot id: A0A3P8Z501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8010:kcnc4
gene id: 8010:kcnc4
uniprot id: A0A3P8YIN7
uniprot id: A0A3P8YIQ4
names: Subcellular Location Annotation
messages: Membrane

8010:pdgfrl
gene id: 8010:pdgfrl
uniprot id: A0A3P8Y1D4
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

8010:rps19bp1
gene id: 8010:rps19bp1
uniprot id: A0A6Q2YBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

8010:gatc
gene id: 8010:gatc
uniprot id: C1BZE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8010:arpc3
gene id: 8010:arpc3
uniprot id: C1BXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8010:si:ch73-335m24.2
gene id: 8010:si:ch73-335m24.2
uniprot id: A0A3P9AGD8
uniprot id: A0A6Q2XAR1
names: Similarity
messages: Belongs to the EVA1 family.

8010:srpx2
gene id: 8010:srpx2
uniprot id: A0A6Q2ZH57
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

8010:tma16
gene id: 8010:tma16
uniprot id: C1BWG2
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

8010:LOC105012027
gene id: 8010:LOC105012027
uniprot id: A0A3P8YQS0
names: Subcellular Location Annotation
messages: Membrane

8010:rrn3
gene id: 8010:rrn3
uniprot id: A0A3P8Z3Q6
names: Similarity
messages: Belongs to the RRN3 family.

8010:mfsd1
gene id: 8010:mfsd1
uniprot id: A0A3P8ZA05
uniprot id: A0A3P9AP73
names: Subcellular Location Annotation
messages: Membrane

8010:pcyox1
gene id: 8010:pcyox1
uniprot id: A0A3P9AF48
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8010:nsun6
gene id: 8010:nsun6
uniprot id: A0A3P8Z3Q4
uniprot id: A0A3P8Z4G8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8010:six6a
gene id: 8010:six6a
uniprot id: A0A3P8Y286
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

8010:edc4
gene id: 8010:edc4
uniprot id: A0A3P9A8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

8010:trnau1apb
gene id: 8010:trnau1apb
uniprot id: A0A3P8YK13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

8010:acad9
gene id: 8010:acad9
uniprot id: A0A3P8Y9W5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:LOC105019819
gene id: 8010:LOC105019819
uniprot id: A0A3P8XQD6
uniprot id: A0A3P8ZL08
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8010:LOC105010727
gene id: 8010:LOC105010727
uniprot id: A0A3P9A2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8010:wasf3b
gene id: 8010:wasf3b
uniprot id: A0A3P8YDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8010:sts
gene id: 8010:sts
uniprot id: A0A3P9A8V2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:arl1
gene id: 8010:arl1
uniprot id: C1BXG7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8010:nudt19
gene id: 8010:nudt19
uniprot id: A0A3P9AAY9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8010:serpinf1
gene id: 8010:serpinf1
uniprot id: A0A3P8XJK0
names: Similarity
messages: Belongs to the serpin family.

8010:mfsd9
gene id: 8010:mfsd9
uniprot id: A0A3P8YZ04
names: Subcellular Location Annotation
messages: Membrane

8010:tradd
gene id: 8010:tradd
uniprot id: A0A3P8ZZG2
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

8010:hsf5
gene id: 8010:hsf5
uniprot id: A0A3P8YVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8010:LOC105031199
gene id: 8010:LOC105031199
uniprot id: A0A3P8ZI37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8010:LOC105025935
gene id: 8010:LOC105025935
uniprot id: A0A3P8Z5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:arhgef6
gene id: 8010:arhgef6
uniprot id: A0A3P8XF85
uniprot id: A0A3P8XGP8
names: Subcellular Location Annotation
messages: lamellipodium

8010:gpc3
gene id: 8010:gpc3
uniprot id: A0A3P8XZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

8010:meis1b
gene id: 8010:meis1b
uniprot id: A0A3P8YFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8010:LOC105012603
gene id: 8010:LOC105012603
uniprot id: A0A3P8ZLF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:tlcd4a
gene id: 8010:tlcd4a
uniprot id: A0A3P8XBI1
names: Subcellular Location Annotation
messages: Membrane

8010:lrp10
gene id: 8010:lrp10
uniprot id: A0A3P8XBE2
uniprot id: A0A3P8XBG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:jph2
gene id: 8010:jph2
uniprot id: A0A3P8ZMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8010:narf
gene id: 8010:narf
uniprot id: A0A3P9AMR5
uniprot id: A0A6Q2WS61
names: Similarity
messages: Belongs to the NARF family.

8010:LOC105018675
gene id: 8010:LOC105018675
uniprot id: A0A6Q2X6Z6
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8010:LOC105015177
gene id: 8010:LOC105015177
uniprot id: A0A3P8XLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8010:evlb
gene id: 8010:evlb
uniprot id: A0A3P8Y8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

8010:LOC105007348
gene id: 8010:LOC105007348
uniprot id: A0A3P8YIT8
uniprot id: A0A3P8YJX8
names: Subcellular Location Annotation
messages: Cytoplasm

8010:LOC105016293
gene id: 8010:LOC105016293
uniprot id: A0A3P8XLD0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:LOC105015733
gene id: 8010:LOC105015733
uniprot id: A0A3P8X8B4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:lmx1a
gene id: 8010:lmx1a
uniprot id: A0A3P8Y3K5
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105015941
gene id: 8010:LOC105015941
uniprot id: A0A3P8Y0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8010:LOC105013747
gene id: 8010:LOC105013747
uniprot id: A0A3P9AFM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8010:LOC105029719
gene id: 8010:LOC105029719
uniprot id: A0A3P8ZMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8010:gcdhb
gene id: 8010:gcdhb
uniprot id: A0A3P8ZVE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:LOC105022979
gene id: 8010:LOC105022979
uniprot id: A0A3P8Y7E6
uniprot id: A0A3P9A0F0
uniprot id: A0A3P9A0H7
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8010:taz
gene id: 8010:taz
uniprot id: A0A6Q2X6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

8010:cfap36
gene id: 8010:cfap36
uniprot id: A0A3P8ZJ86
names: Similarity
messages: Belongs to the CFAP36 family.

8010:tubgcp3
gene id: 8010:tubgcp3
uniprot id: A0A3P8XIJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8010:LOC105020893
gene id: 8010:LOC105020893
uniprot id: A0A3P9A044
names: Subcellular Location Annotation
messages: Nucleus

8010:rpl7l1
gene id: 8010:rpl7l1
uniprot id: A0A3P8ZGP9
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8010:kdm2aa
gene id: 8010:kdm2aa
uniprot id: A0A3P8YXE8
uniprot id: A0A3P9AH73
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8010:wnt9a
gene id: 8010:wnt9a
uniprot id: A0A3P9ALL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8010:LOC105006510
gene id: 8010:LOC105006510
uniprot id: A0A3P8Y729
names: Similarity
messages: Belongs to the peptidase M67C family.

8010:LOC105029919
gene id: 8010:LOC105029919
uniprot id: A0A3P8XFB5
uniprot id: A0A3P8ZHZ9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:syf2
gene id: 8010:syf2
uniprot id: C1BXQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

8010:fut8a
gene id: 8010:fut8a
uniprot id: A0A3P8Z992
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

8010:LOC105023152
gene id: 8010:LOC105023152
uniprot id: A0A3P8X8I9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8010:tbpl1
gene id: 8010:tbpl1
uniprot id: A0A3P8ZM08
names: Similarity
messages: Belongs to the TBP family.

8010:psenen
gene id: 8010:psenen
uniprot id: C1BWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

8010:fam83b
gene id: 8010:fam83b
uniprot id: A0A3P8YWN8
names: Similarity
messages: Belongs to the FAM83 family.

8010:LOC105019315
gene id: 8010:LOC105019315
uniprot id: A0A3P8YWI7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8010:cabz01093075.1
gene id: 8010:cabz01093075.1
uniprot id: A0A3P8XQL4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:tafa4b
gene id: 8010:tafa4b
uniprot id: A0A3P8XN72
names: Similarity
messages: Belongs to the TAFA family.

8010:spats2
gene id: 8010:spats2
uniprot id: A0A3P8ZA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

8010:rab14
gene id: 8010:rab14
uniprot id: A0A3P8XXR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8010:runx3
gene id: 8010:runx3
uniprot id: A0A6Q2XM89
names: Subcellular Location Annotation
messages: Nucleus

8010:isca1
gene id: 8010:isca1
uniprot id: A0A3P8Y9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

f2
gene id: 8010:il17a/f2
uniprot id: A0A3P8XLB6
names: Similarity
messages: Belongs to the IL-17 family.

8010:LOC105030728
gene id: 8010:LOC105030728
uniprot id: A0A3P9A9E0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8010:sulf2b
gene id: 8010:sulf2b
uniprot id: A0A3P8Y3T2
uniprot id: A0A3P8Y4J4
uniprot id: A0A3P8ZVY6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:appl2
gene id: 8010:appl2
uniprot id: A0A3P8ZRZ9
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

8010:tph1a
gene id: 8010:tph1a
uniprot id: A0A3P8Z0U0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8010:kri1
gene id: 8010:kri1
uniprot id: A0A3P8XYR4
names: Similarity
messages: Belongs to the KRI1 family.

8010:im:7154036
gene id: 8010:im:7154036
uniprot id: A0A3P9A964
names: Similarity
messages: Belongs to the kindlin family.

8010:gtpbp3
gene id: 8010:gtpbp3
uniprot id: A0A3P9AEF5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

8010:fam155a
gene id: 8010:fam155a
uniprot id: A0A3P8XMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

8010:htatsf1
gene id: 8010:htatsf1
uniprot id: A0A3P8ZIW1
names: Similarity
messages: Belongs to the HTATSF1 family.

8010:cldn5a
gene id: 8010:cldn5a
uniprot id: A0A3P8ZT90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8010:pdcb
gene id: 8010:pdcb
uniprot id: A0A3P8YWP6
names: Similarity
messages: Belongs to the phosducin family.

8010:gpr180
gene id: 8010:gpr180
uniprot id: A0A3P8XF62
names: Subcellular Location Annotation
messages: Membrane

8010:f8
gene id: 8010:f8
uniprot id: A0A3P8ZKN1
names: Similarity
messages: Belongs to the multicopper oxidase family.

8010:glg1a
gene id: 8010:glg1a
uniprot id: A0A3P8ZMM5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

8010:zgc:114200
gene id: 8010:zgc:114200
uniprot id: A0A3P8YLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

8010:kif26ab
gene id: 8010:kif26ab
uniprot id: A0A3P8XVL3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8010:arglu1a
gene id: 8010:arglu1a
uniprot id: A0A3P8YDN3
names: Similarity
messages: Belongs to the UPF0430 family.

8010:rasgrp3
gene id: 8010:rasgrp3
uniprot id: A0A3P8YB19
uniprot id: A0A3P9A1B3
uniprot id: A0A6Q2XQE8
names: Similarity
messages: Belongs to the RASGRP family.

8010:penka
gene id: 8010:penka
uniprot id: A0A3P9AGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

8010:LOC105018354
gene id: 8010:LOC105018354
uniprot id: A0A3P8XGQ7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:yrdc
gene id: 8010:yrdc
uniprot id: A0A3P8YPT6
names: Similarity
messages: Belongs to the SUA5 family.

8010:mea1
gene id: 8010:mea1
uniprot id: A0A3P9A8G8
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

8010:dus4l
gene id: 8010:dus4l
uniprot id: A0A3P8YNJ2
uniprot id: A0A3P9AB69
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

8010:ltb4r
gene id: 8010:ltb4r
uniprot id: A0A3P8XQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105023132
gene id: 8010:LOC105023132
uniprot id: A0A3P8ZD57
names: Similarity
messages: Belongs to the sorting nexin family.

8010:traf6
gene id: 8010:traf6
uniprot id: A0A3P8YYH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

8010:nudt1
gene id: 8010:nudt1
uniprot id: A0A6Q2Z2T3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8010:hpse
gene id: 8010:hpse
uniprot id: A0A3P8ZD73
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

8010:aldh1l1
gene id: 8010:aldh1l1
uniprot id: A0A3P9A056
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8010:LOC105027164
gene id: 8010:LOC105027164
uniprot id: A0A3P9AC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:LOC105026415
gene id: 8010:LOC105026415
uniprot id: A0A6Q2X0U0
names: Similarity
messages: Belongs to the copine family.

8010:LOC105008817
gene id: 8010:LOC105008817
uniprot id: A0A3P8Z7J2
names: Similarity
messages: Belongs to the peptidase C2 family.

8010:cdk2
gene id: 8010:cdk2
uniprot id: A0A3P9AHD0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:tpd52l1
gene id: 8010:tpd52l1
uniprot id: A0A3P9AHK6
names: Similarity
messages: Belongs to the TPD52 family.

8010:dmbx1a
gene id: 8010:dmbx1a
uniprot id: A0A3P8YUB5
names: Subcellular Location Annotation
messages: Nucleus

8010:pabpc1a
gene id: 8010:pabpc1a
uniprot id: A0A3P8XC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8010:tm7sf3
gene id: 8010:tm7sf3
uniprot id: A0A3P8XBQ7
names: Subcellular Location Annotation
messages: Membrane

8010:dop1a
gene id: 8010:dop1a
uniprot id: A0A3P9AIQ9
uniprot id: A0A3P9AIY8
names: Similarity
messages: Belongs to the dopey family.

8010:LOC105007982
gene id: 8010:LOC105007982
uniprot id: A0A3P8ZLW3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8010:tmem70
gene id: 8010:tmem70
uniprot id: A0A3P8YCV5
names: Similarity
messages: Belongs to the TMEM70 family.

8010:rarga
gene id: 8010:rarga
uniprot id: A0A3P8XQP9
uniprot id: A0A3P8ZPZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8010:LOC105013840
gene id: 8010:LOC105013840
uniprot id: A0A3P8XM20
uniprot id: A0A3P8ZMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8010:tgfb5
gene id: 8010:tgfb5
uniprot id: A0A3P8XSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8010:si:ch211-195d17.2
gene id: 8010:si:ch211-195d17.2
uniprot id: A0A6Q2XLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8010:en1b
gene id: 8010:en1b
uniprot id: A0A3P8YZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8010:glrx2
gene id: 8010:glrx2
uniprot id: A0A3P8ZFE4
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8010:LOC105027901
gene id: 8010:LOC105027901
uniprot id: A0A3P8Z8F0
names: Subcellular Location Annotation
messages: Nucleus

8010:nop56
gene id: 8010:nop56
uniprot id: A0A3P8ZTR3
uniprot id: A0A6Q2XCZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

8010:uckl1a
gene id: 8010:uckl1a
uniprot id: A0A3P8Z4R5
uniprot id: A0A3P9AKX3
uniprot id: A0A6Q2X8K7
names: Similarity
messages: Belongs to the uridine kinase family.

8010:gadd45gip1
gene id: 8010:gadd45gip1
uniprot id: A0A3P8Y068
uniprot id: C1BW10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
messages: Belongs to the mitochondrion-specific ribosomal protein mL64 family.
messages: Mitochondrion
messages: Nucleus

8010:wasf3a
gene id: 8010:wasf3a
uniprot id: A0A3P8Z2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8010:pou4f1
gene id: 8010:pou4f1
uniprot id: A0A3P8ZE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8010:LOC105026826
gene id: 8010:LOC105026826
uniprot id: A0A3P8YQJ6
uniprot id: A0A3P8YQS1
uniprot id: A0A3P8YRQ1
uniprot id: A0A3P9ABS2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8010:pih1d2
gene id: 8010:pih1d2
uniprot id: A0A3P8Z0F3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:arsa
gene id: 8010:arsa
uniprot id: A0A3P8Z4E0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:tspan2a
gene id: 8010:tspan2a
uniprot id: A0A3P8Z7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:unc119b
gene id: 8010:unc119b
uniprot id: A0A3P8XKF7
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8010:cnfn
gene id: 8010:cnfn
uniprot id: A0A3P9ADA7
names: Similarity
messages: Belongs to the cornifelin family.

8010:LOC105021078
gene id: 8010:LOC105021078
uniprot id: A0A3P8XQH7
uniprot id: A0A3P8XTL5
uniprot id: A0A3P8ZNM2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

8010:frk
gene id: 8010:frk
uniprot id: A0A3P9AAK2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8010:LOC105021172
gene id: 8010:LOC105021172
uniprot id: A0A3P9A7I9
names: Subcellular Location Annotation
messages: Nucleus

8010:zgc:110789
gene id: 8010:zgc:110789
uniprot id: A0A3P9ACH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8010:LOC105025863
gene id: 8010:LOC105025863
uniprot id: A0A3P9AKH9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8010:LOC105019469
gene id: 8010:LOC105019469
uniprot id: A0A3P8Z9T5
uniprot id: A0A3P9APW3
names: Similarity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.

8010:slu7
gene id: 8010:slu7
uniprot id: A0A3P8Z4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8010:poc1bl
gene id: 8010:poc1bl
uniprot id: A0A3P8Z0F6
uniprot id: A0A6Q2Z2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8010:erg
gene id: 8010:erg
uniprot id: A0A3P9A1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:LOC105028411
gene id: 8010:LOC105028411
uniprot id: A0A3P8Y008
names: Subcellular Location Annotation
messages: Nucleus

8010:foxi1
gene id: 8010:foxi1
uniprot id: A0A3P8YDH9
names: Subcellular Location Annotation
messages: Nucleus

8010:hcn3
gene id: 8010:hcn3
uniprot id: A0A3P8XVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8010:stat3
gene id: 8010:stat3
uniprot id: A0A3P8YS89
uniprot id: A0A6Q2WXE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8010:b4gat1
gene id: 8010:b4gat1
uniprot id: A0A3P8ZH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

8010:myo1hb
gene id: 8010:myo1hb
uniprot id: A0A3P8Z1H2
uniprot id: A0A3P9AJ78
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8010:slc25a46
gene id: 8010:slc25a46
uniprot id: A0A3P8ZGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:ncbp2
gene id: 8010:ncbp2
uniprot id: C1BY64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By simi…
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Cytoplasm
messages: Nucleus

8010:LOC105006441
gene id: 8010:LOC105006441
uniprot id: A0A3P8YPG9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:LOC105016082
gene id: 8010:LOC105016082
uniprot id: A0A3P8YFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

8010:nkx3-1
gene id: 8010:nkx3-1
uniprot id: A0A3P9AA91
names: Subcellular Location Annotation
messages: Nucleus

8010:tpd52
gene id: 8010:tpd52
uniprot id: A0A3P8ZG42
names: Similarity
messages: Belongs to the TPD52 family.

8010:LOC105031415
gene id: 8010:LOC105031415
uniprot id: A0A3P8ZVA4
names: Similarity
messages: Belongs to the FAM168 family.

8010:paics
gene id: 8010:paics
uniprot id: A0A3P8XHI3
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

8010:gdpd5a
gene id: 8010:gdpd5a
uniprot id: A0A3P8XH67
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8010:LOC105027929
gene id: 8010:LOC105027929
uniprot id: A0A3P8ZFV6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8010:setdb2
gene id: 8010:setdb2
uniprot id: A0A3P8Z9V4
names: Subcellular Location Annotation
messages: Chromosome

8010:LOC109614623
gene id: 8010:LOC109614623
uniprot id: A0A3P8Y6U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:slc8a4b
gene id: 8010:slc8a4b
uniprot id: A0A3P8Y4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8010:mfap2
gene id: 8010:mfap2
uniprot id: A0A3P8YAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

8010:loxl2a
gene id: 8010:loxl2a
uniprot id: A0A3P9AMT0
uniprot id: A0A6Q2XIG6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8010:rps13
gene id: 8010:rps13
uniprot id: C1BWN9
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

8010:tmem230a
gene id: 8010:tmem230a
uniprot id: C1BX22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

8010:LOC105031142
gene id: 8010:LOC105031142
uniprot id: A0A6Q2WRG1
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

8010:parvaa
gene id: 8010:parvaa
uniprot id: A0A3P8YEP6
uniprot id: A0A3P8YEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

8010:slc41a2a
gene id: 8010:slc41a2a
uniprot id: A0A3P8XR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8010:ftsj1
gene id: 8010:ftsj1
uniprot id: A0A3P8Y5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

8010:LOC105027392
gene id: 8010:LOC105027392
uniprot id: A0A3P8ZUK2
names: Subcellular Location Annotation
messages: Nucleus

8010:cep55l
gene id: 8010:cep55l
uniprot id: A0A3P8XHS4
names: Subcellular Location Annotation
messages: Cytoplasm

8010:faxca
gene id: 8010:faxca
uniprot id: A0A3P8XI70
names: Similarity
messages: Belongs to the FAX family.

8010:scarb2a
gene id: 8010:scarb2a
uniprot id: A0A3P8YEY2
uniprot id: A0A3P9A414
names: Similarity
messages: Belongs to the CD36 family.

8010:pycr1a
gene id: 8010:pycr1a
uniprot id: A0A3P8YCE3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8010:mcm8
gene id: 8010:mcm8
uniprot id: A0A3P8YBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8010:slc39a4
gene id: 8010:slc39a4
uniprot id: A0A3P8Z3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

8010:smim7
gene id: 8010:smim7
uniprot id: A0A3P8ZZG1
names: Similarity
messages: Belongs to the SMIM7 family.

8010:lin28a
gene id: 8010:lin28a
uniprot id: A0A3P8ZVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

8010:si:ch211-45c16.2
gene id: 8010:si:ch211-45c16.2
uniprot id: A0A3P8Y0F3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8010:LOC105011204
gene id: 8010:LOC105011204
uniprot id: A0A3P8YT16
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8010:kitb
gene id: 8010:kitb
uniprot id: A0A3P8XZ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:LOC105012574
gene id: 8010:LOC105012574
uniprot id: A0A3P8ZPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8010:csdc2b
gene id: 8010:csdc2b
uniprot id: A0A3P8ZP19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8010:LOC105010699
gene id: 8010:LOC105010699
uniprot id: A0A3P8YP79
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8010:LOC105024259
gene id: 8010:LOC105024259
uniprot id: A0A3P8YGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8010:tmem63c
gene id: 8010:tmem63c
uniprot id: A0A3P8ZQB3
uniprot id: A0A3P8ZQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8010:aar2
gene id: 8010:aar2
uniprot id: A0A3P8XBE3
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

8010:nipa2
gene id: 8010:nipa2
uniprot id: A0A3P8XWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8010:LOC105012856
gene id: 8010:LOC105012856
uniprot id: A0A3P9A093
names: Similarity
messages: Belongs to the SNF7 family.

8010:casp7
gene id: 8010:casp7
uniprot id: A0A6Q2XUX8
names: Similarity
messages: Belongs to the peptidase C14A family.

8010:csrnp3
gene id: 8010:csrnp3
uniprot id: A0A3P9AGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8010:LOC105013973
gene id: 8010:LOC105013973
uniprot id: A0A3P8ZBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

8010:cdo1
gene id: 8010:cdo1
uniprot id: A0A3P9ACR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

8010:mtmr8
gene id: 8010:mtmr8
uniprot id: A0A3P8ZVD2
uniprot id: A0A6Q2Y0J3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8010:chrm2a
gene id: 8010:chrm2a
uniprot id: A0A3P8X862
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8010:cart2
gene id: 8010:cart2
uniprot id: A0A3P8XH23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8010:imp4
gene id: 8010:imp4
uniprot id: A0A3P8ZGV1
names: Subcellular Location Annotation
messages: nucleolus

8010:zgc:103482
gene id: 8010:zgc:103482
uniprot id: A0A3P8Y4E2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:stk17a
gene id: 8010:stk17a
uniprot id: A0A3P8Z7K0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:vps37bb
gene id: 8010:vps37bb
uniprot id: A0A3P8XFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8010:acox1
gene id: 8010:acox1
uniprot id: A0A3P8XR21
uniprot id: A0A3P8ZPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

8010:LOC105016972
gene id: 8010:LOC105016972
uniprot id: A0A3P8YXX6
uniprot id: A0A3P9AHL9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8010:LOC105026498
gene id: 8010:LOC105026498
uniprot id: A0A3P8YTI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:pms1
gene id: 8010:pms1
uniprot id: A0A3P8YAM6
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

8010:gabrp
gene id: 8010:gabrp
uniprot id: A0A3P8XMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:ndufs5
gene id: 8010:ndufs5
uniprot id: C1BWU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

8010:tceanc2
gene id: 8010:tceanc2
uniprot id: A0A3P8YEU3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105017437
gene id: 8010:LOC105017437
uniprot id: A0A3P8XC18
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8010:LOC105010739
gene id: 8010:LOC105010739
uniprot id: A0A3P8YRW7
names: Similarity
messages: Belongs to the peptidase C19 family.

8010:zgc:113223
gene id: 8010:zgc:113223
uniprot id: A0A3P8XGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8010:LOC105010391
gene id: 8010:LOC105010391
uniprot id: A0A3P9A073
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8010:LOC105010258
gene id: 8010:LOC105010258
uniprot id: A0A3P8XNX2
uniprot id: A0A3P8ZNQ8
uniprot id: A0A6Q2Y7L4
names: Similarity
messages: Belongs to the TOM1 family.

8010:taf12
gene id: 8010:taf12
uniprot id: A0A6Q2XTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

8010:gramd1c
gene id: 8010:gramd1c
uniprot id: A0A3P9A2Q0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:LOC105006790
gene id: 8010:LOC105006790
uniprot id: A0A3P8YLX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105013374
gene id: 8010:LOC105013374
uniprot id: A0A3P9AKJ0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:agpat5
gene id: 8010:agpat5
uniprot id: A0A3P9AFP6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:LOC105023037
gene id: 8010:LOC105023037
uniprot id: A0A3P9ANN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:slc9a8
gene id: 8010:slc9a8
uniprot id: A0A3P8X7L9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

8010:LOC105022025
gene id: 8010:LOC105022025
uniprot id: A0A3P8Y2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8010:LOC105025939
gene id: 8010:LOC105025939
uniprot id: A0A3P9AE21
uniprot id: A0A3P9AE26
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105014760
gene id: 8010:LOC105014760
uniprot id: A0A3P8ZDV6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:cmpk2
gene id: 8010:cmpk2
uniprot id: A0A3P8YAB9
names: Similarity
messages: Belongs to the thymidylate kinase family.

8010:med17
gene id: 8010:med17
uniprot id: A0A3P8YGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8010:tacr2
gene id: 8010:tacr2
uniprot id: A0A3P8YRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:p2rx2
gene id: 8010:p2rx2
uniprot id: A0A3P8ZEK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8010:hsd17b2
gene id: 8010:hsd17b2
uniprot id: A0A3P8YP19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:map4k6
gene id: 8010:map4k6
uniprot id: A0A3P8XEI0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8010:pih1d1
gene id: 8010:pih1d1
uniprot id: C1BYV8
names: Similarity
messages: Belongs to the PIH1 family.

8010:LOC105019960
gene id: 8010:LOC105019960
uniprot id: A0A3P8YSH1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:LOC105017094
gene id: 8010:LOC105017094
uniprot id: A0A3P8Z374
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

8010:taf1b
gene id: 8010:taf1b
uniprot id: A0A3P9A335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

8010:LOC105011698
gene id: 8010:LOC105011698
uniprot id: A0A3P9A080
uniprot id: A0A6Q2YW95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

8010:LOC105007540
gene id: 8010:LOC105007540
uniprot id: A0A3P9AMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8010:tmed3
gene id: 8010:tmed3
uniprot id: C1BYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8010:snupn
gene id: 8010:snupn
uniprot id: A0A3P9AN29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

8010:c14h9orf78
gene id: 8010:c14h9orf78
uniprot id: A0A3P9AMQ4
names: Similarity
messages: Belongs to the TLS1 family.

8010:dlx5a
gene id: 8010:dlx5a
uniprot id: A0A3P8YUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8010:si:dkey-283b1.7
gene id: 8010:si:dkey-283b1.7
uniprot id: A0A3P8XQM8
names: Subcellular Location Annotation
messages: Synapse

8010:suds3
gene id: 8010:suds3
uniprot id: A0A3P8XGM7
uniprot id: A0A3P8ZHU4
names: Subcellular Location Annotation
messages: Nucleus

8010:lbx1a
gene id: 8010:lbx1a
uniprot id: A0A3P8YFS6
names: Subcellular Location Annotation
messages: Nucleus

8010:rap2c
gene id: 8010:rap2c
uniprot id: A0A3P8ZD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8010:efna3a
gene id: 8010:efna3a
uniprot id: A0A3P8X9D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:tmem121b
gene id: 8010:tmem121b
uniprot id: A0A3P8Y594
names: Similarity
messages: Belongs to the TMEM121 family.

8010:cmc4
gene id: 8010:cmc4
uniprot id: A0A3P8YE38
names: Similarity
messages: Belongs to the CMC4 family.

8010:LOC105011350
gene id: 8010:LOC105011350
uniprot id: A0A3P8XJ95
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8010:LOC105025974
gene id: 8010:LOC105025974
uniprot id: A0A3P9AN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

8010:ppa1b
gene id: 8010:ppa1b
uniprot id: A0A6Q2Z469
names: Similarity
messages: Belongs to the PPase family.

8010:LOC105010649
gene id: 8010:LOC105010649
uniprot id: A0A3P8ZNS7
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8010:atf1
gene id: 8010:atf1
uniprot id: A0A3P8YSM0
names: Subcellular Location Annotation
messages: Nucleus

8010:serpina10a
gene id: 8010:serpina10a
uniprot id: A0A3P8ZMS3
names: Similarity
messages: Belongs to the serpin family.

8010:arl6ip5a
gene id: 8010:arl6ip5a
uniprot id: C1BXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8010:LOC105030602
gene id: 8010:LOC105030602
uniprot id: A0A3P8XS53
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

8010:rpl27a
gene id: 8010:rpl27a
uniprot id: C1BYP9
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

8010:fgf1a
gene id: 8010:fgf1a
uniprot id: A0A3P9ANH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8010:grpel1
gene id: 8010:grpel1
uniprot id: A0A3P8ZX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

8010:egr2b
gene id: 8010:egr2b
uniprot id: A0A3P8YLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8010:LOC105024412
gene id: 8010:LOC105024412
uniprot id: A0A3P8ZIT7
uniprot id: A0A6Q2Z4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105023177
gene id: 8010:LOC105023177
uniprot id: A0A3P8ZC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8010:blmh
gene id: 8010:blmh
uniprot id: A0A3P8ZU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

8010:eif1b
gene id: 8010:eif1b
uniprot id: A0A3P8XC87
names: Similarity
messages: Belongs to the SUI1 family.

8010:lamp1b
gene id: 8010:lamp1b
uniprot id: A0A3P8YZ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

8010:hmgcll1
gene id: 8010:hmgcll1
uniprot id: A0A3P8YX43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

8010:dlat
gene id: 8010:dlat
uniprot id: A0A3P8XAD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

8010:ngrn
gene id: 8010:ngrn
uniprot id: A0A6Q2YLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

8010:eloal
gene id: 8010:eloal
uniprot id: A0A3P8YXE0
uniprot id: A0A3P9AGE6
uniprot id: A0A3P9AGJ0
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105019766
gene id: 8010:LOC105019766
uniprot id: C1BZK3
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8010:LOC105012736
gene id: 8010:LOC105012736
uniprot id: A0A3P8Y800
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8010:plpp4
gene id: 8010:plpp4
uniprot id: A0A3P8Y3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8010:mvda
gene id: 8010:mvda
uniprot id: A0A3P8Y287
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8010:gpat4
gene id: 8010:gpat4
uniprot id: A0A3P9AGE4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8010:LOC105024679
gene id: 8010:LOC105024679
uniprot id: A0A3P8XRP7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8010:arsj
gene id: 8010:arsj
uniprot id: A0A3P8Y4S7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8010:coro1ca
gene id: 8010:coro1ca
uniprot id: A0A3P8Y9G9
names: Similarity
messages: Belongs to the WD repeat coronin family.

8010:msh6
gene id: 8010:msh6
uniprot id: A0A3P8XZJ5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

8010:LOC105031590
gene id: 8010:LOC105031590
uniprot id: A0A3P9AIW9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8010:LOC105024986
gene id: 8010:LOC105024986
uniprot id: A0A3P8YI66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

8010:parga
gene id: 8010:parga
uniprot id: A0A3P9A0W9
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8010:LOC105018077
gene id: 8010:LOC105018077
uniprot id: A0A3P9A7G8
uniprot id: A0A6Q2YWD5
names: Similarity
messages: Belongs to the UPF0046 family.

8010:actc1c
gene id: 8010:actc1c
uniprot id: A0A3P8ZUX3
names: Similarity
messages: Belongs to the actin family.

8010:LOC105010648
gene id: 8010:LOC105010648
uniprot id: A0A3P8ZQ24
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8010:LOC105010572
gene id: 8010:LOC105010572
uniprot id: A0A3P8XLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8010:zgc:55461
gene id: 8010:zgc:55461
uniprot id: A0A3P8YXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8010:mcm4
gene id: 8010:mcm4
uniprot id: A0A3P9AIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

8010:h3f3c
gene id: 8010:h3f3c
uniprot id: A0A3P9AEN1
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8010:LOC105031086
gene id: 8010:LOC105031086
uniprot id: A0A3P8ZLZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:foxa2
gene id: 8010:foxa2
uniprot id: A0A3P8ZEL3
names: Subcellular Location Annotation
messages: Nucleus

8010:si:ch211-234h8.7
gene id: 8010:si:ch211-234h8.7
uniprot id: A0A3P8Y226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8010:rab42a
gene id: 8010:rab42a
uniprot id: A0A3P8XZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8010:LOC105006931
gene id: 8010:LOC105006931
uniprot id: A0A3P8Z441
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

8010:cacybp
gene id: 8010:cacybp
uniprot id: C1BVY9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

8010:elf2b
gene id: 8010:elf2b
uniprot id: A0A3P8Y2S5
uniprot id: A0A3P8Y5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8010:LOC105009876
gene id: 8010:LOC105009876
uniprot id: A0A3P8Y5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:LOC105017864
gene id: 8010:LOC105017864
uniprot id: A0A3P8YN99
uniprot id: A0A6Q2XT18
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:tmem47
gene id: 8010:tmem47
uniprot id: A0A3P8YDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8010:mixl1
gene id: 8010:mixl1
uniprot id: A0A3P8YMI5
names: Subcellular Location Annotation
messages: Nucleus

8010:sap30l
gene id: 8010:sap30l
uniprot id: A0A3P8YVL3
names: Similarity
messages: Belongs to the SAP30 family.

8010:cers2a
gene id: 8010:cers2a
uniprot id: A0A3P8ZKK8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8010:emc3
gene id: 8010:emc3
uniprot id: A0A3P8YNC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8010:LOC105021889
gene id: 8010:LOC105021889
uniprot id: A0A6Q2Y2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8010:vps26c
gene id: 8010:vps26c
uniprot id: A0A3P9A141
names: Similarity
messages: Belongs to the VPS26 family.

8010:LOC105022623
gene id: 8010:LOC105022623
uniprot id: A0A3P9A185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8010:LOC105024045
gene id: 8010:LOC105024045
uniprot id: A0A3P8Z7I3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8010:flot2b
gene id: 8010:flot2b
uniprot id: A0A3P8XTM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8010:fam160a2
gene id: 8010:fam160a2
uniprot id: A0A3P8YEM7
uniprot id: A0A3P9A5B1
names: Similarity
messages: Belongs to the FHIP family.

8010:LOC105011093
gene id: 8010:LOC105011093
uniprot id: A0A3P8XWY9
names: Subcellular Location Annotation
messages: Membrane

8010:guk1b
gene id: 8010:guk1b
uniprot id: A0A3P8YGP6
uniprot id: A0A3P9A5Q5
names: Similarity
messages: Belongs to the guanylate kinase family.

8010:hoxa5a
gene id: 8010:hoxa5a
uniprot id: A0A3P8XGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8010:tbxta
gene id: 8010:tbxta
uniprot id: A0A3P8ZXD0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:si:ch211-260e23.9
gene id: 8010:si:ch211-260e23.9
uniprot id: A0A3P8YWW4
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8010:syngr1a
gene id: 8010:syngr1a
uniprot id: A0A3P8ZZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8010:LOC105010493
gene id: 8010:LOC105010493
uniprot id: A0A3P8XHU5
uniprot id: A0A3P8XJ62
uniprot id: A0A3P8ZGU7
uniprot id: A0A3P8ZH13
uniprot id: A0A3P8ZHV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8010:hsf1
gene id: 8010:hsf1
uniprot id: A0A3P8Z2S2
uniprot id: A0A3P8Z3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8010:ilvbl
gene id: 8010:ilvbl
uniprot id: A0A3P9AAU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane

8010:ddr2a
gene id: 8010:ddr2a
uniprot id: A0A6Q2ZK95
names: Subcellular Location Annotation
messages: Membrane

8010:gprin3
gene id: 8010:gprin3
uniprot id: A0A3P9A4M7
names: Function
messages: May be involved in neurite outgrowth.

8010:LOC105026264
gene id: 8010:LOC105026264
uniprot id: A0A3P9AB59
names: Similarity
messages: Belongs to the arrestin family.

8010:LOC105020441
gene id: 8010:LOC105020441
uniprot id: A0A3P8ZPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8010:chrnb1l
gene id: 8010:chrnb1l
uniprot id: A0A3P8Z780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8010:LOC105017884
gene id: 8010:LOC105017884
uniprot id: A0A3P9AA49
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8010:ppm1na
gene id: 8010:ppm1na
uniprot id: A0A3P9A2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8010:itpk1b
gene id: 8010:itpk1b
uniprot id: A0A3P8ZUT8
names: Similarity
messages: Belongs to the ITPK1 family.

8010:cdk2ap2
gene id: 8010:cdk2ap2
uniprot id: A0A6Q2ZE07
names: Similarity
messages: Belongs to the CDK2AP family.

8010:LOC105023790
gene id: 8010:LOC105023790
uniprot id: A0A3P9A0S8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:LOC105021620
gene id: 8010:LOC105021620
uniprot id: A0A3P8ZPH9
uniprot id: A0A3P8ZPR8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8010:cnn3a
gene id: 8010:cnn3a
uniprot id: A0A3P8ZDN3
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8010:gpr34l
gene id: 8010:gpr34l
uniprot id: A0A3P8YEQ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8010:rad23aa
gene id: 8010:rad23aa
uniprot id: A0A3P8XX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8010:cspg4b
gene id: 8010:cspg4b
uniprot id: A0A3P9AN57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ccna1
gene id: 8010:ccna1
uniprot id: A0A3P8XTB5
names: Similarity
messages: Belongs to the cyclin family.

8010:faslg
gene id: 8010:faslg
uniprot id: A0A3P8ZP09
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8010:fam228a
gene id: 8010:fam228a
uniprot id: A0A3P8ZP66
names: Similarity
messages: Belongs to the FAM228 family.

8010:slc17a6a
gene id: 8010:slc17a6a
uniprot id: A0A3P8YZN3
names: Subcellular Location Annotation
messages: Membrane

8010:ucp1
gene id: 8010:ucp1
uniprot id: A0A3P8YGQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:pot1
gene id: 8010:pot1
uniprot id: A0A3P8XHX4
uniprot id: A0A3P8ZJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

8010:LOC105013014
gene id: 8010:LOC105013014
uniprot id: A0A3P8ZLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

8010:mto1
gene id: 8010:mto1
uniprot id: A0A3P8Z601
names: Function
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

8010:golm1
gene id: 8010:golm1
uniprot id: A0A3P8X9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8010:cacna2d2b
gene id: 8010:cacna2d2b
uniprot id: A0A3P8XXF7
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8010:LOC105015264
gene id: 8010:LOC105015264
uniprot id: A0A3P8XF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8010:mief1
gene id: 8010:mief1
uniprot id: A0A3P8Y1S5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8010:LOC105017614
gene id: 8010:LOC105017614
uniprot id: A0A3P8XGA0
uniprot id: A0A6Q2XT55
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8010:LOC105022090
gene id: 8010:LOC105022090
uniprot id: A0A3P8YW45
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8010:ndufab1b
gene id: 8010:ndufab1b
uniprot id: C1BY11
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

8010:rhot1a
gene id: 8010:rhot1a
uniprot id: A0A3P8XSJ9
uniprot id: A0A3P8ZR57
uniprot id: A0A6Q2XYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8010:LOC105006879
gene id: 8010:LOC105006879
uniprot id: A0A3P8YV32
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8010:foxf1
gene id: 8010:foxf1
uniprot id: A0A3P8ZW76
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105022338
gene id: 8010:LOC105022338
uniprot id: A0A3P8Z798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

8010:LOC105024660
gene id: 8010:LOC105024660
uniprot id: A0A3P8ZIE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8010:acadsb
gene id: 8010:acadsb
uniprot id: A0A3P8YFW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8010:cnp
gene id: 8010:cnp
uniprot id: A0A3P9AB74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

8010:ptprz1b
gene id: 8010:ptprz1b
uniprot id: A0A3P8YL07
uniprot id: A0A3P9A9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8010:LOC105022376
gene id: 8010:LOC105022376
uniprot id: A0A3P8Z153
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105018391
gene id: 8010:LOC105018391
uniprot id: A0A3P8XWT7
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

8010:wdyhv1
gene id: 8010:wdyhv1
uniprot id: A0A3P9ALW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

8010:esr2a
gene id: 8010:esr2a
uniprot id: A0A3P8ZLM9
uniprot id: A0A6Q2X2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8010:ehd1a
gene id: 8010:ehd1a
uniprot id: A0A3P8XRT0
uniprot id: A0A3P8XRT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8010:gata3
gene id: 8010:gata3
uniprot id: A0A3P8XM97
names: Subcellular Location Annotation
messages: Nucleus

8010:med9
gene id: 8010:med9
uniprot id: A0A3P8YE20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8010:gpsm2
gene id: 8010:gpsm2
uniprot id: A0A3P8Y026
names: Similarity
messages: Belongs to the GPSM family.

8010:fam57a
gene id: 8010:fam57a
uniprot id: C1BWY7
names: Subcellular Location Annotation
messages: Membrane

8010:stx4
gene id: 8010:stx4
uniprot id: A0A3P8XVU3
names: Similarity
messages: Belongs to the syntaxin family.

8010:msto1
gene id: 8010:msto1
uniprot id: A0A3P8YGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

8010:rnf121
gene id: 8010:rnf121
uniprot id: A0A3P8XRH3
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105016900
gene id: 8010:LOC105016900
uniprot id: A0A3P8X8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8010:LOC105030384
gene id: 8010:LOC105030384
uniprot id: A0A6Q2ZL56
names: Subcellular Location Annotation
messages: Membrane

8010:slc1a9
gene id: 8010:slc1a9
uniprot id: A0A3P8YTU6
uniprot id: A0A3P8YV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:wdr35
gene id: 8010:wdr35
uniprot id: A0A3P9A931
uniprot id: A0A3P9AA16
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

8010:LOC105019405
gene id: 8010:LOC105019405
uniprot id: A0A3P8XHY3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:LOC105008768
gene id: 8010:LOC105008768
uniprot id: A0A3P8ZFD8
names: Similarity
messages: Belongs to the pyridoxine kinase family.

8010:atp6ap2
gene id: 8010:atp6ap2
uniprot id: A0A3P8YTR8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

8010:smarcal1
gene id: 8010:smarcal1
uniprot id: A0A3P8XZQ9
uniprot id: A0A3P8XZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

8010:coro2a
gene id: 8010:coro2a
uniprot id: A0A3P9A735
uniprot id: A0A6Q2WY16
names: Similarity
messages: Belongs to the WD repeat coronin family.

8010:taf5
gene id: 8010:taf5
uniprot id: A0A3P8ZHR6
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8010:leprotl1
gene id: 8010:leprotl1
uniprot id: A0A6Q2XYD7
uniprot id: C1BVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8010:vsnl1a
gene id: 8010:vsnl1a
uniprot id: A0A3P8XZK9
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

8010:lrp5
gene id: 8010:lrp5
uniprot id: A0A3P8XYM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:slco3a1
gene id: 8010:slco3a1
uniprot id: A0A3P8YRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8010:eral1
gene id: 8010:eral1
uniprot id: A0A3P8Z2J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

8010:LOC105018348
gene id: 8010:LOC105018348
uniprot id: C1BWN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8010:ccdc149a
gene id: 8010:ccdc149a
uniprot id: A0A3P9A9B6
names: Similarity
messages: Belongs to the CCDC149 family.

8010:LOC105026474
gene id: 8010:LOC105026474
uniprot id: A0A3P8ZCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

8010:lnpk
gene id: 8010:lnpk
uniprot id: A0A3P9AIR3
uniprot id: A0A3P9AJK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8010:cipca
gene id: 8010:cipca
uniprot id: A0A3P8ZPW7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8010:mrps16
gene id: 8010:mrps16
uniprot id: A0A6Q2WR11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

8010:tpra1
gene id: 8010:tpra1
uniprot id: A0A3P8Y387
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8010:eipr1
gene id: 8010:eipr1
uniprot id: A0A3P8ZDZ3
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

8010:kcnj3a
gene id: 8010:kcnj3a
uniprot id: A0A3P8YK41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8010:ap1b1
gene id: 8010:ap1b1
uniprot id: A0A3P8YAD8
uniprot id: A0A3P8YCG5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8010:fth1b
gene id: 8010:fth1b
uniprot id: A0A3P9AM97
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8010:spg7
gene id: 8010:spg7
uniprot id: A0A3P8YQC9
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8010:si:dkey-246g23.2
gene id: 8010:si:dkey-246g23.2
uniprot id: A0A3P8YDT6
names: Subcellular Location Annotation
messages: Membrane

8010:kcnk10a
gene id: 8010:kcnk10a
uniprot id: A0A3P8ZT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8010:LOC105027567
gene id: 8010:LOC105027567
uniprot id: A0A3P8Z630
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8010:LOC105027928
gene id: 8010:LOC105027928
uniprot id: A0A6Q2WS36
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8010:adcy5
gene id: 8010:adcy5
uniprot id: A0A6Q2X2K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8010:LOC105020313
gene id: 8010:LOC105020313
uniprot id: A0A3P8ZN09
names: Similarity
messages: Belongs to the GORASP family.

8010:LOC105027620
gene id: 8010:LOC105027620
uniprot id: A0A3P8ZLB5
names: Similarity
messages: Belongs to the PA28 family.

8010:s1pr5b
gene id: 8010:s1pr5b
uniprot id: A0A3P8Z7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8010:LOC105027027
gene id: 8010:LOC105027027
uniprot id: A0A3P8Z0I0
uniprot id: A0A3P8Z0N3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8010:bicc2
gene id: 8010:bicc2
uniprot id: A0A3P8YTC9
names: Similarity
messages: Belongs to the BicC family.

8010:LOC105012724
gene id: 8010:LOC105012724
uniprot id: A0A3P8YAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8010:mnx1
gene id: 8010:mnx1
uniprot id: A0A3P8ZL25
names: Subcellular Location Annotation
messages: Nucleus

8010:ercc2
gene id: 8010:ercc2
uniprot id: A0A3P9AAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

8010:rps11
gene id: 8010:rps11
uniprot id: A0A3P8YWI4
uniprot id: C1BYW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8010:mrpl32
gene id: 8010:mrpl32
uniprot id: C1BZQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8010:LOC105027111
gene id: 8010:LOC105027111
uniprot id: A0A3P8XAA6
names: Subcellular Location Annotation
messages: Membrane

8010:adam8a
gene id: 8010:adam8a
uniprot id: A0A3P8ZSV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:tmem35
gene id: 8010:tmem35
uniprot id: A0A6Q2YG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

8010:chmp2a
gene id: 8010:chmp2a
uniprot id: A0A3P8XYH0
names: Similarity
messages: Belongs to the SNF7 family.

8010:LOC105010549
gene id: 8010:LOC105010549
uniprot id: C1BWP7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:cfap299
gene id: 8010:cfap299
uniprot id: A0A3P9A182
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

8010:LOC105023043
gene id: 8010:LOC105023043
uniprot id: A0A3P8Z7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8010:LOC105009636
gene id: 8010:LOC105009636
uniprot id: A0A6Q2ZML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8010:cks1b
gene id: 8010:cks1b
uniprot id: A0A3P8ZRB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8010:sms
gene id: 8010:sms
uniprot id: A0A3P9AFP4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

8010:vps52
gene id: 8010:vps52
uniprot id: A0A3P9AE36
names: Similarity
messages: Belongs to the VPS52 family.

8010:LOC105015311
gene id: 8010:LOC105015311
uniprot id: A0A3P9A120
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8010:zfyve28
gene id: 8010:zfyve28
uniprot id: A0A3P8Y0H6
names: Similarity
messages: Belongs to the lst-2 family.

8010:sox12
gene id: 8010:sox12
uniprot id: A0A3P8Z5N5
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105012883
gene id: 8010:LOC105012883
uniprot id: A0A3P8YK92
names: Subcellular Location Annotation
messages: Membrane

8010:pfas
gene id: 8010:pfas
uniprot id: A0A3P8ZYC0
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

8010:slc1a8b
gene id: 8010:slc1a8b
uniprot id: A0A3P8XS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8010:LOC105025825
gene id: 8010:LOC105025825
uniprot id: A0A3P8YI76
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8010:qkia
gene id: 8010:qkia
uniprot id: A0A3P8YE34
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8010:tle2a
gene id: 8010:tle2a
uniprot id: A0A3P9A8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8010:hoxd3a
gene id: 8010:hoxd3a
uniprot id: A0A3P8Z660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8010:nkx3.3
gene id: 8010:nkx3.3
uniprot id: A0A3P8Z1K3
names: Subcellular Location Annotation
messages: Nucleus

8010:LOC105014643
gene id: 8010:LOC105014643
uniprot id: A0A3P8YKY6
uniprot id: A0A3P9A6U6
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8010:LOC105009572
gene id: 8010:LOC105009572
uniprot id: A0A3P8ZFL6
names: Similarity
messages: Belongs to the TOM1 family.

8010:pebp1
gene id: 8010:pebp1
uniprot id: A0A6Q2XWA1
uniprot id: C1BX85
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

8010:LOC105013758
gene id: 8010:LOC105013758
uniprot id: C1BYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8010:endog
gene id: 8010:endog
uniprot id: A0A3P9A6J2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8010:LOC105023796
gene id: 8010:LOC105023796
uniprot id: A0A3P9A171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8010:rpe65a
gene id: 8010:rpe65a
uniprot id: A0A3P8Z0I1
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

8010:pycard
gene id: 8010:pycard
uniprot id: C1BXR4
names: Subcellular Location Annotation
messages: Inflammasome

8010:gga1
gene id: 8010:gga1
uniprot id: A0A3P8ZDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

8010:gpsm1b
gene id: 8010:gpsm1b
uniprot id: A0A3P8YFH1
names: Similarity
messages: Belongs to the GPSM family.

8010:ak1
gene id: 8010:ak1
uniprot id: A0A3P8YFA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

8010:cdc37l1
gene id: 8010:cdc37l1
uniprot id: A0A3P8ZNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8010:mmp23bb
gene id: 8010:mmp23bb
uniprot id: A0A3P8XL65
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:alas1
gene id: 8010:alas1
uniprot id: A0A3P8YFW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8010:dgcr6
gene id: 8010:dgcr6
uniprot id: C1BZ19
names: Similarity
messages: Belongs to the gonadal family.

8010:atp23
gene id: 8010:atp23
uniprot id: A0A3P8XH19
names: Similarity
messages: Belongs to the peptidase M76 family.

8010:kcng2
gene id: 8010:kcng2
uniprot id: A0A3P9A0E8
names: Subcellular Location Annotation
messages: Membrane

8010:phka1a
gene id: 8010:phka1a
uniprot id: A0A6Q2XQY8
uniprot id: A0A6Q2ZP84
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

8010:rpl10a
gene id: 8010:rpl10a
uniprot id: A0A3P8ZWW8
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

8010:otulinb
gene id: 8010:otulinb
uniprot id: A0A3P8YNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

8010:LOC105016174
gene id: 8010:LOC105016174
uniprot id: A0A3P8Y950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

8010:adcyap1a
gene id: 8010:adcyap1a
uniprot id: A0A3P8XTF7
uniprot id: A0A3P8XVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8010:pfdn2
gene id: 8010:pfdn2
uniprot id: A0A3P8ZI20
uniprot id: A0A3P8ZIG4
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

8010:LOC105007772
gene id: 8010:LOC105007772
uniprot id: A0A3P8Y8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8010:epn1
gene id: 8010:epn1
uniprot id: A0A3P8YKG7
uniprot id: A0A3P9A831
names: Similarity
messages: Belongs to the epsin family.

8010:scg2b
gene id: 8010:scg2b
uniprot id: A0A3P8ZXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8010:dhrs7b
gene id: 8010:dhrs7b
uniprot id: A0A3P8XXD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8010:ndufv1
gene id: 8010:ndufv1
uniprot id: A0A3P8XVQ7
uniprot id: A0A3P8XVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

8010:LOC105007227
gene id: 8010:LOC105007227
uniprot id: A0A3P8ZKV7
names: Subcellular Location Annotation
messages: Membrane

8010:LOC105021584
gene id: 8010:LOC105021584
uniprot id: A0A3P9A552
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8010:tgfa
gene id: 8010:tgfa
uniprot id: A0A3P8X8I2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:gata6
gene id: 8010:gata6
uniprot id: A0A3P8ZAH9
names: Subcellular Location Annotation
messages: Nucleus

8010:alas2
gene id: 8010:alas2
uniprot id: A0A3P8XRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8010:igf1
gene id: 8010:igf1
uniprot id: A0A3P8XEJ4
uniprot id: A0A3P8ZG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8010:fam160a1a
gene id: 8010:fam160a1a
uniprot id: A0A3P8YAB6
uniprot id: A0A3P8YCH1
names: Similarity
messages: Belongs to the FHIP family.

8010:tsen2
gene id: 8010:tsen2
uniprot id: A0A3P8YAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8010:tyk2
gene id: 8010:tyk2
uniprot id: A0A3P9ANB0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

8010:zfhx4
gene id: 8010:zfhx4
uniprot id: A0A3P8ZU57
names: Subcellular Location Annotation
messages: Nucleus

8010:dennd6aa
gene id: 8010:dennd6aa
uniprot id: A0A3P9A4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

8010:ufd1l
gene id: 8010:ufd1l
uniprot id: C1BWN8
names: Similarity
messages: Belongs to the UFD1 family.

8010:si:ch211-183d21.3
gene id: 8010:si:ch211-183d21.3
uniprot id: A0A3P8ZSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

8010:abraxas2
gene id: 8010:abraxas2
uniprot id: A0A3P8XLG5
names: Subcellular Location Annotation
messages: Nucleus

8010:npr3
gene id: 8010:npr3
uniprot id: A0A3P8Z4T1
names: Subcellular Location Annotation
messages: Membrane

8010:mus81
gene id: 8010:mus81
uniprot id: A0A3P8ZSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

8010:pik3c3
gene id: 8010:pik3c3
uniprot id: A0A3P8XGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

8010:ddx11
gene id: 8010:ddx11
uniprot id: A0A3P8Z2V5
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

8010:cpt1cb
gene id: 8010:cpt1cb
uniprot id: A0A3P9AKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8010:LOC105023134
gene id: 8010:LOC105023134
uniprot id: A0A3P8ZCW3
names: Subcellular Location Annotation
messages: cytoskeleton

8010:LOC105013720
gene id: 8010:LOC105013720
uniprot id: A0A3P9AFH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

8010:gart
gene id: 8010:gart
uniprot id: A0A3P8X723
uniprot id: A0A3P8ZCI9
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

8010:toe1
gene id: 8010:toe1
uniprot id: A0A6Q2X6M8
names: Similarity
messages: Belongs to the CAF1 family.

8010:cdh31
gene id: 8010:cdh31
uniprot id: A0A3P8YTE7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

8010:crabp2b
gene id: 8010:crabp2b
uniprot id: C1BZ63
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8010:hdc
gene id: 8010:hdc
uniprot id: A0A6Q2XZH2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8010:cstf1
gene id: 8010:cstf1
uniprot id: A0A3P8YBK6
names: Subcellular Location Annotation
messages: Nucleus

8010:tmbim1a
gene id: 8010:tmbim1a
uniprot id: A0A3P8XK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8010:atp2b1a
gene id: 8010:atp2b1a
uniprot id: A0A3P8Z9M8
uniprot id: A0A3P8ZAJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8010:clic3
gene id: 8010:clic3
uniprot id: C1BX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

8010:fam20a
gene id: 8010:fam20a
uniprot id: A0A6Q2XU60
names: Similarity
messages: Belongs to the FAM20 family.

8010:LOC105030675
gene id: 8010:LOC105030675
uniprot id: A0A3P8Y2M4
uniprot id: A0A3P8Y5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8010:trpt1
gene id: 8010:trpt1
uniprot id: A0A3P8XT80
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8010:adhfe1
gene id: 8010:adhfe1
uniprot id: A0A3P8ZT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

8010:atf4a
gene id: 8010:atf4a
uniprot id: A0A3P8YZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

8010:clcn1b
gene id: 8010:clcn1b
uniprot id: A0A3P9A9W3
names: Subcellular Location Annotation
messages: Membrane

8010:arg1
gene id: 8010:arg1
uniprot id: A0A3P8ZIR7
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8010:hat1
gene id: 8010:hat1
uniprot id: A0A3P8Z229
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

8010:aldh7a1
gene id: 8010:aldh7a1
uniprot id: A0A3P8YRA9
uniprot id: A0A6Q2ZCN1
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

8010:bmp7b
gene id: 8010:bmp7b
uniprot id: A0A3P8YKT4
names: Similarity
messages: Belongs to the TGF-beta family.

8010:znf330
gene id: 8010:znf330
uniprot id: A0A3P8YFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

8010:trmt112
gene id: 8010:trmt112
uniprot id: C1BZ33
names: Similarity
messages: Belongs to the TRM112 family.

8010:wdr83os
gene id: 8010:wdr83os
uniprot id: C1BZN9
names: Similarity
messages: Belongs to the Asterix family.

8010:supt5h
gene id: 8010:supt5h
uniprot id: A0A3P8ZXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

8010:gh1
gene id: 8010:gh1
uniprot id: P34744
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation.
messages: Secreted

8010:pi4k2a
gene id: 8010:pi4k2a
uniprot id: A0A3P9AAI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8010:pi4k2b
gene id: 8010:pi4k2b
uniprot id: A0A3P8XUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8010:supt20
gene id: 8010:supt20
uniprot id: A0A3P8XTZ9
names: Similarity
messages: Belongs to the SPT20 family.

8010:slc6a3
gene id: 8010:slc6a3
uniprot id: A0A3P8X986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8010:LOC105018372
gene id: 8010:LOC105018372
uniprot id: A0A3P8XL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8010:LOC105021314
gene id: 8010:LOC105021314
uniprot id: A0A3P8XXL5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8010:klc4
gene id: 8010:klc4
uniprot id: A0A3P8YKV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8010:f5
gene id: 8010:f5
uniprot id: A0A3P8YQ91
names: Similarity
messages: Belongs to the multicopper oxidase family.

8010:atp6v1ab
gene id: 8010:atp6v1ab
uniprot id: A0A3P8YCB1
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8010:si:dkey-197c15.6
gene id: 8010:si:dkey-197c15.6
uniprot id: A0A3P8ZNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8010:scamp3
gene id: 8010:scamp3
uniprot id: A0A3P8ZPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8010:eomesb
gene id: 8010:eomesb
uniprot id: A0A3P8XD01
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8010:glra1
gene id: 8010:glra1
uniprot id: A0A3P8Z370
uniprot id: A0A3P8Z4X3
uniprot id: A0A3P8Z4Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

8010:ube2ia
gene id: 8010:ube2ia
uniprot id: A0A3P8Z133
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8010:actr3
gene id: 8010:actr3
uniprot id: C1BWF5
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

8010:LOC105029941
gene id: 8010:LOC105029941
uniprot id: A0A3P8XKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8010:hibadha
gene id: 8010:hibadha
uniprot id: A0A3P8XLJ0
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8010:LOC105027758
gene id: 8010:LOC105027758
uniprot id: A0A3P8Y162
names: Similarity
messages: Belongs to the DNase I family.

8010:LOC105016180
gene id: 8010:LOC105016180
uniprot id: A0A3P9A1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8010:smc4
gene id: 8010:smc4
uniprot id: A0A3P8Z946
uniprot id: A0A3P8Z9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

8010:bmp3
gene id: 8010:bmp3
uniprot id: A0A3P9A1D1
names: Similarity
messages: Belongs to the TGF-beta family.

8010:gba
gene id: 8010:gba
uniprot id: A0A3P9A0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

8010:tada1
gene id: 8010:tada1
uniprot id: A0A3P8XAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8010:nlgn1
gene id: 8010:nlgn1
uniprot id: A0A3P8XZX2
uniprot id: A0A3P8Y156
uniprot id: A0A3P8ZTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8010:homer1b
gene id: 8010:homer1b
uniprot id: A0A3P8XAI7
uniprot id: A0A3P8ZAV3
uniprot id: A0A6Q2WZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8010:LOC105010533
gene id: 8010:LOC105010533
uniprot id: A0A3P8ZIA0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8010:pamr1
gene id: 8010:pamr1
uniprot id: A0A3P8XF87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:rrad
gene id: 8010:rrad
uniprot id: A0A6Q2X879
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8010:aldh3b1
gene id: 8010:aldh3b1
uniprot id: A0A3P8Z922
uniprot id: A0A3P9ANE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8010:habp2
gene id: 8010:habp2
uniprot id: A0A3P8ZX64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8010:ubn2b
gene id: 8010:ubn2b
uniprot id: A0A3P8Y2N9
uniprot id: A0A3P8ZW37
names: Similarity
messages: Belongs to the ubinuclein family.

8010:osbpl3a
gene id: 8010:osbpl3a
uniprot id: A0A3P8XMD3
uniprot id: A0A3P8ZJA7
names: Similarity
messages: Belongs to the OSBP family.

8010:ephx1
gene id: 8010:ephx1
uniprot id: A0A3P8XDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8010:bnip3
gene id: 8010:bnip3
uniprot id: A0A3P9A3L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8010:cemip2
gene id: 8010:cemip2
uniprot id: A0A3P8X885
names: Similarity
messages: Belongs to the CEMIP family.

8010:LOC105022514
gene id: 8010:LOC105022514
uniprot id: A0A3P8YM71
names: Subcellular Location Annotation
messages: Nucleus

8010:serpine1
gene id: 8010:serpine1
uniprot id: A0A3P8XZA0
names: Similarity
messages: Belongs to the serpin family.

8010:LOC105017298
gene id: 8010:LOC105017298
uniprot id: A0A3P8ZMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8010:polr3b
gene id: 8010:polr3b
uniprot id: A0A3P8Z924
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.