797299:HALLA RS00290
gene id: 797299:HALLA_RS00290
uniprot id: W0JMF1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

797299:HALLA RS13810
gene id: 797299:HALLA_RS13810
uniprot id: W0JTL0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797299:HALLA RS16325
gene id: 797299:HALLA_RS16325
uniprot id: W0JWJ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

797299:HALLA RS10295
gene id: 797299:HALLA_RS10295
uniprot id: W0JRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

797299:HALLA RS14120
gene id: 797299:HALLA_RS14120
uniprot id: W0JVW8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS07350
gene id: 797299:HALLA_RS07350
uniprot id: W0JR90
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

797299:HALLA RS00485
gene id: 797299:HALLA_RS00485
uniprot id: W0JM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

797299:HALLA RS00115
gene id: 797299:HALLA_RS00115
uniprot id: W0JMB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02875
gene id: 797299:HALLA_RS02875
uniprot id: W0JNB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797299:HALLA RS18095
gene id: 797299:HALLA_RS18095
uniprot id: W0JXQ9
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS19560
gene id: 797299:HALLA_RS19560
uniprot id: W0JZM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS11045
gene id: 797299:HALLA_RS11045
uniprot id: W0JS97
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

797299:HALLA RS11455
gene id: 797299:HALLA_RS11455
uniprot id: W0JSI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797299:HALLA RS09530
gene id: 797299:HALLA_RS09530
uniprot id: W0JRU0
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

797299:HALLA RS17925
gene id: 797299:HALLA_RS17925
uniprot id: W0JXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS04120
gene id: 797299:HALLA_RS04120
uniprot id: W0JK85
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS00470
gene id: 797299:HALLA_RS00470
uniprot id: W0JIE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

797299:HALLA RS17395
gene id: 797299:HALLA_RS17395
uniprot id: W0JY46
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS02190
gene id: 797299:HALLA_RS02190
uniprot id: W0JNR7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

797299:HALLA RS04280
gene id: 797299:HALLA_RS04280
uniprot id: W0JPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797299:HALLA RS02850
gene id: 797299:HALLA_RS02850
uniprot id: W0JNA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797299:HALLA RS10275
gene id: 797299:HALLA_RS10275
uniprot id: W0JSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

797299:HALLA RS11315
gene id: 797299:HALLA_RS11315
uniprot id: W0JSF3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS01420
gene id: 797299:HALLA_RS01420
uniprot id: W0JMV9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS05095
gene id: 797299:HALLA_RS05095
uniprot id: W0JPD9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

797299:HALLA RS13850
gene id: 797299:HALLA_RS13850
uniprot id: W0JPX3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

797299:HALLA RS12770
gene id: 797299:HALLA_RS12770
uniprot id: W0JTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

797299:HALLA RS09890
gene id: 797299:HALLA_RS09890
uniprot id: W0JMZ0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797299:HALLA RS15180
gene id: 797299:HALLA_RS15180
uniprot id: W0JWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797299:HALLA RS06060
gene id: 797299:HALLA_RS06060
uniprot id: W0JKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

797299:HALLA RS17630
gene id: 797299:HALLA_RS17630
uniprot id: W0JY99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS13110
gene id: 797299:HALLA_RS13110
uniprot id: W0JT87
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

797299:HALLA RS01030
gene id: 797299:HALLA_RS01030
uniprot id: W0JIM4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797299:HALLA RS07385
gene id: 797299:HALLA_RS07385
uniprot id: W0JQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

797299:HALLA RS03635
gene id: 797299:HALLA_RS03635
uniprot id: W0JP24
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797299:HALLA RS09240
gene id: 797299:HALLA_RS09240
uniprot id: W0JMM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS07525
gene id: 797299:HALLA_RS07525
uniprot id: W0JQH7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

797299:HALLA RS18455
gene id: 797299:HALLA_RS18455
uniprot id: W0JU82
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

797299:HALLA RS13890
gene id: 797299:HALLA_RS13890
uniprot id: W0JPL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS12825
gene id: 797299:HALLA_RS12825
uniprot id: W0JTX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

797299:HALLA RS16285
gene id: 797299:HALLA_RS16285
uniprot id: W0JSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS09560
gene id: 797299:HALLA_RS09560
uniprot id: W0JRU5
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

797299:HALLA RS09830
gene id: 797299:HALLA_RS09830
uniprot id: W0JRN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS04075
gene id: 797299:HALLA_RS04075
uniprot id: W0JJT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS11350
gene id: 797299:HALLA_RS11350
uniprot id: W0JNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797299:HALLA RS00195
gene id: 797299:HALLA_RS00195
uniprot id: W0JHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS00795
gene id: 797299:HALLA_RS00795
uniprot id: W0JMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

797299:HALLA RS15745
gene id: 797299:HALLA_RS15745
uniprot id: W0JWX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

797299:HALLA RS15825
gene id: 797299:HALLA_RS15825
uniprot id: W0JW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797299:HALLA RS15060
gene id: 797299:HALLA_RS15060
uniprot id: W0JWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS13125
gene id: 797299:HALLA_RS13125
uniprot id: W0JPK4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

797299:HALLA RS07175
gene id: 797299:HALLA_RS07175
uniprot id: W0JQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS06275
gene id: 797299:HALLA_RS06275
uniprot id: W0JQE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797299:HALLA RS03825
gene id: 797299:HALLA_RS03825
uniprot id: W0JP56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

797299:HALLA RS13910
gene id: 797299:HALLA_RS13910
uniprot id: W0JUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797299:HALLA RS04085
gene id: 797299:HALLA_RS04085
uniprot id: W0JPT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS03595
gene id: 797299:HALLA_RS03595
uniprot id: W0JNN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

797299:HALLA RS03845
gene id: 797299:HALLA_RS03845
uniprot id: W0JK32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

797299:HALLA RS00850
gene id: 797299:HALLA_RS00850
uniprot id: W0JMA3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02000
gene id: 797299:HALLA_RS02000
uniprot id: W0JNN1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

797299:HALLA RS18125
gene id: 797299:HALLA_RS18125
uniprot id: W0JU26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797299:HALLA RS11930
gene id: 797299:HALLA_RS11930
uniprot id: W0JP21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797299:HALLA RS08275
gene id: 797299:HALLA_RS08275
uniprot id: W0JR62
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS18140
gene id: 797299:HALLA_RS18140
uniprot id: W0JXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS09625
gene id: 797299:HALLA_RS09625
uniprot id: W0JSF7
names: Similarity
messages: Belongs to the archease family.

797299:HALLA RS02100
gene id: 797299:HALLA_RS02100
uniprot id: W0JMT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS08400
gene id: 797299:HALLA_RS08400
uniprot id: W0JRQ7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS03625
gene id: 797299:HALLA_RS03625
uniprot id: W0JPK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

797299:HALLA RS16605
gene id: 797299:HALLA_RS16605
uniprot id: W0JXI7
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS10450
gene id: 797299:HALLA_RS10450
uniprot id: W0JMW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797299:HALLA RS10280
gene id: 797299:HALLA_RS10280
uniprot id: W0JN57
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02985
gene id: 797299:HALLA_RS02985
uniprot id: W0JJ99
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

797299:HALLA RS05730
gene id: 797299:HALLA_RS05730
uniprot id: W0JQN4
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

797299:HALLA RS09000
gene id: 797299:HALLA_RS09000
uniprot id: W0JMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

797299:HALLA RS12945
gene id: 797299:HALLA_RS12945
uniprot id: W0JT66
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797299:HALLA RS07100
gene id: 797299:HALLA_RS07100
uniprot id: W0JQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797299:HALLA RS14880
gene id: 797299:HALLA_RS14880
uniprot id: W0JT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS11755
gene id: 797299:HALLA_RS11755
uniprot id: W0JSX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

797299:HALLA RS03805
gene id: 797299:HALLA_RS03805
uniprot id: W0JJM8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

797299:HALLA RS09550
gene id: 797299:HALLA_RS09550
uniprot id: W0JSE5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

797299:HALLA RS08840
gene id: 797299:HALLA_RS08840
uniprot id: W0JMD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS05070
gene id: 797299:HALLA_RS05070
uniprot id: W0JPD3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

797299:HALLA RS15500
gene id: 797299:HALLA_RS15500
uniprot id: W0JW68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02570
gene id: 797299:HALLA_RS02570
uniprot id: W0JN32
names: Similarity
messages: Belongs to the UPF0173 family.

797299:HALLA RS08540
gene id: 797299:HALLA_RS08540
uniprot id: W0JM82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

797299:HALLA RS09800
gene id: 797299:HALLA_RS09800
uniprot id: W0JRM8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS03140
gene id: 797299:HALLA_RS03140
uniprot id: W0JPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

797299:HALLA RS10865
gene id: 797299:HALLA_RS10865
uniprot id: W0JSF1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10690
gene id: 797299:HALLA_RS10690
uniprot id: W0JNC3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS11790
gene id: 797299:HALLA_RS11790
uniprot id: W0JNM9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS12990
gene id: 797299:HALLA_RS12990
uniprot id: W0JTD6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

797299:HALLA RS11475
gene id: 797299:HALLA_RS11475
uniprot id: W0JNF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

797299:HALLA RS15175
gene id: 797299:HALLA_RS15175
uniprot id: W0JVT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS06490
gene id: 797299:HALLA_RS06490
uniprot id: W0JL06
names: Similarity
messages: Belongs to the RutC family.

797299:HALLA RS19455
gene id: 797299:HALLA_RS19455
uniprot id: W0JV10
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS18150
gene id: 797299:HALLA_RS18150
uniprot id: W0JU31
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS11450
gene id: 797299:HALLA_RS11450
uniprot id: W0JNF0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14955
gene id: 797299:HALLA_RS14955
uniprot id: W0JVX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS11640
gene id: 797299:HALLA_RS11640
uniprot id: W0JNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

797299:HALLA RS19565
gene id: 797299:HALLA_RS19565
uniprot id: W0JV40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10085
gene id: 797299:HALLA_RS10085
uniprot id: W0JN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS14150
gene id: 797299:HALLA_RS14150
uniprot id: W0JRH7
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS00505
gene id: 797299:HALLA_RS00505
uniprot id: W0JI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797299:HALLA RS00780
gene id: 797299:HALLA_RS00780
uniprot id: W0JM94
names: Similarity
messages: Belongs to the TFIIB family.

797299:HALLA RS17680
gene id: 797299:HALLA_RS17680
uniprot id: W0JTT4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS15970
gene id: 797299:HALLA_RS15970
uniprot id: W0JWI7
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS14045
gene id: 797299:HALLA_RS14045
uniprot id: W0JUG6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS07170
gene id: 797299:HALLA_RS07170
uniprot id: W0JL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS00050
gene id: 797299:HALLA_RS00050
uniprot id: W0JHW6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS08605
gene id: 797299:HALLA_RS08605
uniprot id: W0JR14
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797299:HALLA RS07780
gene id: 797299:HALLA_RS07780
uniprot id: W0JQY1
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

797299:HALLA RS00445
gene id: 797299:HALLA_RS00445
uniprot id: W0JID6
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

797299:HALLA RS10230
gene id: 797299:HALLA_RS10230
uniprot id: W0JS49
names: Similarity
messages: Belongs to the arginase family.

797299:HALLA RS00520
gene id: 797299:HALLA_RS00520
uniprot id: W0JIF0
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

797299:HALLA RS09280
gene id: 797299:HALLA_RS09280
uniprot id: W0JMP0
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

797299:HALLA RS10965
gene id: 797299:HALLA_RS10965
uniprot id: W0JT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

797299:HALLA RS13290
gene id: 797299:HALLA_RS13290
uniprot id: W0JPM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

797299:HALLA RS07900
gene id: 797299:HALLA_RS07900
uniprot id: W0JRH8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00215
gene id: 797299:HALLA_RS00215
uniprot id: W0JMD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

797299:HALLA RS00760
gene id: 797299:HALLA_RS00760
uniprot id: W0JII8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

797299:HALLA RS17800
gene id: 797299:HALLA_RS17800
uniprot id: W0JYD4
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS19585
gene id: 797299:HALLA_RS19585
uniprot id: W0JZN3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797299:HALLA RS07140
gene id: 797299:HALLA_RS07140
uniprot id: W0JQL3
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

797299:HALLA RS12005
gene id: 797299:HALLA_RS12005
uniprot id: W0JNQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS04185
gene id: 797299:HALLA_RS04185
uniprot id: W0JNZ4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

797299:HALLA RS02845
gene id: 797299:HALLA_RS02845
uniprot id: W0JJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

797299:HALLA RS09610
gene id: 797299:HALLA_RS09610
uniprot id: W0JRV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

797299:HALLA RS09445
gene id: 797299:HALLA_RS09445
uniprot id: W0JRS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS07360
gene id: 797299:HALLA_RS07360
uniprot id: W0JQQ4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

797299:HALLA RS09485
gene id: 797299:HALLA_RS09485
uniprot id: W0JRH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

797299:HALLA RS09450
gene id: 797299:HALLA_RS09450
uniprot id: W0JME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS03945
gene id: 797299:HALLA_RS03945
uniprot id: W0JP77
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797299:HALLA RS10040
gene id: 797299:HALLA_RS10040
uniprot id: W0JS23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

797299:HALLA RS04745
gene id: 797299:HALLA_RS04745
uniprot id: W0JPJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS09385
gene id: 797299:HALLA_RS09385
uniprot id: W0JRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797299:HALLA RS12545
gene id: 797299:HALLA_RS12545
uniprot id: W0JNY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

797299:HALLA RS18105
gene id: 797299:HALLA_RS18105
uniprot id: W0JU19
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS09250
gene id: 797299:HALLA_RS09250
uniprot id: W0JMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

797299:HALLA RS05210
gene id: 797299:HALLA_RS05210
uniprot id: W0JQA7
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797299:HALLA RS11145
gene id: 797299:HALLA_RS11145
uniprot id: W0JSJ8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10210
gene id: 797299:HALLA_RS10210
uniprot id: W0JMS5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797299:HALLA RS18165
gene id: 797299:HALLA_RS18165
uniprot id: W0JXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS15535
gene id: 797299:HALLA_RS15535
uniprot id: W0JW13
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03455
gene id: 797299:HALLA_RS03455
uniprot id: W0JPI0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797299:HALLA RS18225
gene id: 797299:HALLA_RS18225
uniprot id: W0JU48
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

797299:HALLA RS09735
gene id: 797299:HALLA_RS09735
uniprot id: W0JRX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797299:HALLA RS03740
gene id: 797299:HALLA_RS03740
uniprot id: W0JP43
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

797299:HALLA RS01680
gene id: 797299:HALLA_RS01680
uniprot id: W0JNH8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

797299:HALLA RS05115
gene id: 797299:HALLA_RS05115
uniprot id: W0JPR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS09500
gene id: 797299:HALLA_RS09500
uniprot id: W0JRT5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797299:HALLA RS10800
gene id: 797299:HALLA_RS10800
uniprot id: W0JSY2
names: Similarity
messages: Belongs to the TPP enzyme family.

797299:HALLA RS10145
gene id: 797299:HALLA_RS10145
uniprot id: W0JMR6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS10500
gene id: 797299:HALLA_RS10500
uniprot id: W0JMX8
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797299:HALLA RS10320
gene id: 797299:HALLA_RS10320
uniprot id: W0JRW2
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS13895
gene id: 797299:HALLA_RS13895
uniprot id: W0JVV2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02715
gene id: 797299:HALLA_RS02715
uniprot id: W0JP13
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

797299:HALLA RS03575
gene id: 797299:HALLA_RS03575
uniprot id: W0JPJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

797299:HALLA RS13560
gene id: 797299:HALLA_RS13560
uniprot id: W0JPE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797299:HALLA RS15735
gene id: 797299:HALLA_RS15735
uniprot id: W0JSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

797299:HALLA RS10520
gene id: 797299:HALLA_RS10520
uniprot id: W0JMY3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

797299:HALLA RS09930
gene id: 797299:HALLA_RS09930
uniprot id: W0JRP9
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

797299:HALLA RS12060
gene id: 797299:HALLA_RS12060
uniprot id: W0JNR3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10135
gene id: 797299:HALLA_RS10135
uniprot id: W0JN36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

797299:HALLA RS09245
gene id: 797299:HALLA_RS09245
uniprot id: W0JRP7
names: Similarity
messages: Belongs to the TrpF family.

797299:HALLA RS00750
gene id: 797299:HALLA_RS00750
uniprot id: W0JM91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS08205
gene id: 797299:HALLA_RS08205
uniprot id: W0JQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

797299:HALLA RS07720
gene id: 797299:HALLA_RS07720
uniprot id: W0JRE5
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS06075
gene id: 797299:HALLA_RS06075
uniprot id: W0JL94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797299:HALLA RS06095
gene id: 797299:HALLA_RS06095
uniprot id: W0JQV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

797299:HALLA RS02200
gene id: 797299:HALLA_RS02200
uniprot id: W0JNA1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

797299:HALLA RS03240
gene id: 797299:HALLA_RS03240
uniprot id: W0JNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797299:HALLA RS14885
gene id: 797299:HALLA_RS14885
uniprot id: W0JX26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS04050
gene id: 797299:HALLA_RS04050
uniprot id: W0JJT0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS17120
gene id: 797299:HALLA_RS17120
uniprot id: W0JX56
names: Similarity
messages: Belongs to the asparaginase 1 family.

797299:HALLA RS13460
gene id: 797299:HALLA_RS13460
uniprot id: W0JTE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

797299:HALLA RS11505
gene id: 797299:HALLA_RS11505
uniprot id: W0JSR1
names: Similarity
messages: Belongs to the Ahb/Nir family.

797299:HALLA RS11180
gene id: 797299:HALLA_RS11180
uniprot id: W0JNA0
names: Similarity
messages: Belongs to the citrate synthase family.

797299:HALLA RS06000
gene id: 797299:HALLA_RS06000
uniprot id: W0JQ94
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

797299:HALLA RS04315
gene id: 797299:HALLA_RS04315
uniprot id: W0JP18
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

797299:HALLA RS06380
gene id: 797299:HALLA_RS06380
uniprot id: W0JQ47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

797299:HALLA RS13360
gene id: 797299:HALLA_RS13360
uniprot id: W0JTC4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03710
gene id: 797299:HALLA_RS03710
uniprot id: W0JK01
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS16620
gene id: 797299:HALLA_RS16620
uniprot id: W0JSW6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

797299:HALLA RS02990
gene id: 797299:HALLA_RS02990
uniprot id: W0JNE3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

797299:HALLA RS03665
gene id: 797299:HALLA_RS03665
uniprot id: W0JJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS07910
gene id: 797299:HALLA_RS07910
uniprot id: W0JR06
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14840
gene id: 797299:HALLA_RS14840
uniprot id: W0JVV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797299:HALLA RS08870
gene id: 797299:HALLA_RS08870
uniprot id: W0JRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

797299:HALLA RS05015
gene id: 797299:HALLA_RS05015
uniprot id: W0JPP1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797299:HALLA RS18810
gene id: 797299:HALLA_RS18810
uniprot id: W0JYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797299:HALLA RS00770
gene id: 797299:HALLA_RS00770
uniprot id: W0JI71
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

797299:HALLA RS13450
gene id: 797299:HALLA_RS13450
uniprot id: W0JTK7
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

797299:HALLA RS03850
gene id: 797299:HALLA_RS03850
uniprot id: W0JP61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

797299:HALLA RS00755
gene id: 797299:HALLA_RS00755
uniprot id: W0JN63
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS09970
gene id: 797299:HALLA_RS09970
uniprot id: W0JRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

797299:HALLA RS15245
gene id: 797299:HALLA_RS15245
uniprot id: W0JS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

797299:HALLA RS01285
gene id: 797299:HALLA_RS01285
uniprot id: W0JMT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02975
gene id: 797299:HALLA_RS02975
uniprot id: W0JJN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS03430
gene id: 797299:HALLA_RS03430
uniprot id: W0JPH6
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

797299:HALLA RS07765
gene id: 797299:HALLA_RS07765
uniprot id: W0JQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS05520
gene id: 797299:HALLA_RS05520
uniprot id: W0JPY0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02955
gene id: 797299:HALLA_RS02955
uniprot id: W0JJ93
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

797299:HALLA RS12650
gene id: 797299:HALLA_RS12650
uniprot id: W0JTV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797299:HALLA RS02355
gene id: 797299:HALLA_RS02355
uniprot id: W0JNC4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS12520
gene id: 797299:HALLA_RS12520
uniprot id: W0JSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797299:HALLA RS00650
gene id: 797299:HALLA_RS00650
uniprot id: W0JM75
names: Similarity
messages: Belongs to the UPF0201 family.

797299:HALLA RS05835
gene id: 797299:HALLA_RS05835
uniprot id: W0JL52
names: Similarity
messages: Belongs to the SDO1/SBDS family.

797299:HALLA RS11650
gene id: 797299:HALLA_RS11650
uniprot id: W0JNL1
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797299:HALLA RS14125
gene id: 797299:HALLA_RS14125
uniprot id: W0JRH2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14495
gene id: 797299:HALLA_RS14495
uniprot id: W0JRT2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05750
gene id: 797299:HALLA_RS05750
uniprot id: W0JPU9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS15075
gene id: 797299:HALLA_RS15075
uniprot id: W0JRS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10150
gene id: 797299:HALLA_RS10150
uniprot id: W0JRT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS06370
gene id: 797299:HALLA_RS06370
uniprot id: W0JQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

797299:HALLA RS13265
gene id: 797299:HALLA_RS13265
uniprot id: W0JPM4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

797299:HALLA RS03065
gene id: 797299:HALLA_RS03065
uniprot id: W0JNT4
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS15990
gene id: 797299:HALLA_RS15990
uniprot id: W0JSN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS06085
gene id: 797299:HALLA_RS06085
uniprot id: W0JKT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

797299:HALLA RS09975
gene id: 797299:HALLA_RS09975
uniprot id: W0JSL0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797299:HALLA RS13405
gene id: 797299:HALLA_RS13405
uniprot id: W0JPB9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS01345
gene id: 797299:HALLA_RS01345
uniprot id: W0JMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

797299:HALLA RS08375
gene id: 797299:HALLA_RS08375
uniprot id: W0JRQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

797299:HALLA RS00160
gene id: 797299:HALLA_RS00160
uniprot id: W0JI90
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

797299:HALLA RS12755
gene id: 797299:HALLA_RS12755
uniprot id: W0JT97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

797299:HALLA RS05385
gene id: 797299:HALLA_RS05385
uniprot id: W0JKT4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

797299:HALLA RS19570
gene id: 797299:HALLA_RS19570
uniprot id: W0JYX4
names: Similarity
messages: Belongs to the cytochrome P450 family.

797299:HALLA RS18145
gene id: 797299:HALLA_RS18145
uniprot id: W0JYL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS08965
gene id: 797299:HALLA_RS08965
uniprot id: W0JRA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

797299:HALLA RS05080
gene id: 797299:HALLA_RS05080
uniprot id: W0JKM4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

797299:HALLA RS07635
gene id: 797299:HALLA_RS07635
uniprot id: W0JLD5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

797299:HALLA RS14380
gene id: 797299:HALLA_RS14380
uniprot id: W0JVH5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797299:HALLA RS09070
gene id: 797299:HALLA_RS09070
uniprot id: W0JRC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

797299:HALLA RS01650
gene id: 797299:HALLA_RS01650
uniprot id: W0JMK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

797299:HALLA RS04350
gene id: 797299:HALLA_RS04350
uniprot id: W0JJX7
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS12410
gene id: 797299:HALLA_RS12410
uniprot id: W0JNW7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS18285
gene id: 797299:HALLA_RS18285
uniprot id: W0JXV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797299:HALLA RS10090
gene id: 797299:HALLA_RS10090
uniprot id: W0JS29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

797299:HALLA RS00690
gene id: 797299:HALLA_RS00690
uniprot id: W0JIH3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797299:HALLA RS10740
gene id: 797299:HALLA_RS10740
uniprot id: W0JS36
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS07145
gene id: 797299:HALLA_RS07145
uniprot id: W0JL43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797299:HALLA RS07845
gene id: 797299:HALLA_RS07845
uniprot id: W0JQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

797299:HALLA RS14105
gene id: 797299:HALLA_RS14105
uniprot id: W0JVA9
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797299:HALLA RS19000
gene id: 797299:HALLA_RS19000
uniprot id: W0JZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797299:HALLA RS10580
gene id: 797299:HALLA_RS10580
uniprot id: W0JSA5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

797299:HALLA RS12240
gene id: 797299:HALLA_RS12240
uniprot id: W0JNU2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

797299:HALLA RS12565
gene id: 797299:HALLA_RS12565
uniprot id: W0JT77
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

797299:HALLA RS11470
gene id: 797299:HALLA_RS11470
uniprot id: W0JSQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

797299:HALLA RS07365
gene id: 797299:HALLA_RS07365
uniprot id: W0JL86
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

797299:HALLA RS06240
gene id: 797299:HALLA_RS06240
uniprot id: W0JQY2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS01900
gene id: 797299:HALLA_RS01900
uniprot id: W0JNL3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

797299:HALLA RS09790
gene id: 797299:HALLA_RS09790
uniprot id: W0JRY5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS11170
gene id: 797299:HALLA_RS11170
uniprot id: W0JNK6
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS00245
gene id: 797299:HALLA_RS00245
uniprot id: W0JHZ4
names: Similarity
messages: Belongs to the TPP enzyme family.

797299:HALLA RS13215
gene id: 797299:HALLA_RS13215
uniprot id: W0JU24
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

797299:HALLA RS06365
gene id: 797299:HALLA_RS06365
uniprot id: W0JLD7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

797299:HALLA RS12350
gene id: 797299:HALLA_RS12350
uniprot id: W0JNV8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797299:HALLA RS05690
gene id: 797299:HALLA_RS05690
uniprot id: W0JKL1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797299:HALLA RS13165
gene id: 797299:HALLA_RS13165
uniprot id: W0JPK9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

797299:HALLA RS08635
gene id: 797299:HALLA_RS08635
uniprot id: W0JMA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

797299:HALLA RS05065
gene id: 797299:HALLA_RS05065
uniprot id: W0JK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797299:HALLA RS01315
gene id: 797299:HALLA_RS01315
uniprot id: W0JID5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

797299:HALLA RS02180
gene id: 797299:HALLA_RS02180
uniprot id: W0JIT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

797299:HALLA RS09650
gene id: 797299:HALLA_RS09650
uniprot id: W0JSG2
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797299:HALLA RS00515
gene id: 797299:HALLA_RS00515
uniprot id: W0JN21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

797299:HALLA RS16535
gene id: 797299:HALLA_RS16535
uniprot id: W0JSU3
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS17690
gene id: 797299:HALLA_RS17690
uniprot id: W0JTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS13445
gene id: 797299:HALLA_RS13445
uniprot id: W0JPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

797299:HALLA RS03400
gene id: 797299:HALLA_RS03400
uniprot id: W0JNK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

797299:HALLA RS01320
gene id: 797299:HALLA_RS01320
uniprot id: W0JMF5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797299:HALLA RS09565
gene id: 797299:HALLA_RS09565
uniprot id: W0JMG1
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

797299:HALLA RS10650
gene id: 797299:HALLA_RS10650
uniprot id: W0JNC0
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS05920
gene id: 797299:HALLA_RS05920
uniprot id: W0JQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

797299:HALLA RS04925
gene id: 797299:HALLA_RS04925
uniprot id: W0JKJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797299:HALLA RS00285
gene id: 797299:HALLA_RS00285
uniprot id: W0JIB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

797299:HALLA RS17035
gene id: 797299:HALLA_RS17035
uniprot id: W0JX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS12130
gene id: 797299:HALLA_RS12130
uniprot id: W0JTM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797299:HALLA RS05350
gene id: 797299:HALLA_RS05350
uniprot id: W0JKD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797299:HALLA RS03365
gene id: 797299:HALLA_RS03365
uniprot id: W0JJF8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

797299:HALLA RS01240
gene id: 797299:HALLA_RS01240
uniprot id: W0JIP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS17835
gene id: 797299:HALLA_RS17835
uniprot id: W0JXT5
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS11770
gene id: 797299:HALLA_RS11770
uniprot id: W0JTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797299:HALLA RS13795
gene id: 797299:HALLA_RS13795
uniprot id: W0JPW6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797299:HALLA RS15170
gene id: 797299:HALLA_RS15170
uniprot id: W0JRU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

797299:HALLA RS02425
gene id: 797299:HALLA_RS02425
uniprot id: W0JNV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

797299:HALLA RS07665
gene id: 797299:HALLA_RS07665
uniprot id: W0JQW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797299:HALLA RS13430
gene id: 797299:HALLA_RS13430
uniprot id: W0JPC4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797299:HALLA RS19370
gene id: 797299:HALLA_RS19370
uniprot id: W0JUV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS15220
gene id: 797299:HALLA_RS15220
uniprot id: W0JRV9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS11205
gene id: 797299:HALLA_RS11205
uniprot id: W0JNA4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

797299:HALLA RS10780
gene id: 797299:HALLA_RS10780
uniprot id: W0JSD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797299:HALLA RS09810
gene id: 797299:HALLA_RS09810
uniprot id: W0JMX5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS09030
gene id: 797299:HALLA_RS09030
uniprot id: W0JRL9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

797299:HALLA RS18560
gene id: 797299:HALLA_RS18560
uniprot id: W0JYU9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

797299:HALLA RS04060
gene id: 797299:HALLA_RS04060
uniprot id: W0JPT1
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

797299:HALLA RS09110
gene id: 797299:HALLA_RS09110
uniprot id: W0JML1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

797299:HALLA RS09260
gene id: 797299:HALLA_RS09260
uniprot id: W0JMN5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

797299:HALLA RS00840
gene id: 797299:HALLA_RS00840
uniprot id: W0JI83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS05510
gene id: 797299:HALLA_RS05510
uniprot id: W0JQG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10950
gene id: 797299:HALLA_RS10950
uniprot id: W0JSG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

797299:HALLA RS08030
gene id: 797299:HALLA_RS08030
uniprot id: W0JQQ6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05915
gene id: 797299:HALLA_RS05915
uniprot id: W0JL68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS14725
gene id: 797299:HALLA_RS14725
uniprot id: W0JRX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS00880
gene id: 797299:HALLA_RS00880
uniprot id: W0JN83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS02475
gene id: 797299:HALLA_RS02475
uniprot id: W0JNW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS09695
gene id: 797299:HALLA_RS09695
uniprot id: W0JRL2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797299:HALLA RS19330
gene id: 797299:HALLA_RS19330
uniprot id: W0JYS7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

797299:HALLA RS08575
gene id: 797299:HALLA_RS08575
uniprot id: W0JRB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

797299:HALLA RS06225
gene id: 797299:HALLA_RS06225
uniprot id: W0JQD2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS02840
gene id: 797299:HALLA_RS02840
uniprot id: W0JNN3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

797299:HALLA RS01425
gene id: 797299:HALLA_RS01425
uniprot id: W0JIF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

797299:HALLA RS10285
gene id: 797299:HALLA_RS10285
uniprot id: W0JS58
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797299:HALLA RS08830
gene id: 797299:HALLA_RS08830
uniprot id: W0JR57
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05845
gene id: 797299:HALLA_RS05845
uniprot id: W0JKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797299:HALLA RS03085
gene id: 797299:HALLA_RS03085
uniprot id: W0JPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS11300
gene id: 797299:HALLA_RS11300
uniprot id: W0JNN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00540
gene id: 797299:HALLA_RS00540
uniprot id: W0JN25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797299:HALLA RS10020
gene id: 797299:HALLA_RS10020
uniprot id: W0JSL6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02900
gene id: 797299:HALLA_RS02900
uniprot id: W0JJ84
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS08450
gene id: 797299:HALLA_RS08450
uniprot id: W0JRR7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797299:HALLA RS10505
gene id: 797299:HALLA_RS10505
uniprot id: W0JSU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02440
gene id: 797299:HALLA_RS02440
uniprot id: W0JIY2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS04000
gene id: 797299:HALLA_RS04000
uniprot id: W0JJS0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

797299:HALLA RS01215
gene id: 797299:HALLA_RS01215
uniprot id: W0JIN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

797299:HALLA RS09100
gene id: 797299:HALLA_RS09100
uniprot id: W0JS74
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS13835
gene id: 797299:HALLA_RS13835
uniprot id: W0JPK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS17735
gene id: 797299:HALLA_RS17735
uniprot id: W0JYC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS10100
gene id: 797299:HALLA_RS10100
uniprot id: W0JRS4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

797299:HALLA RS04025
gene id: 797299:HALLA_RS04025
uniprot id: W0JJS6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS17695
gene id: 797299:HALLA_RS17695
uniprot id: W0JXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS11115
gene id: 797299:HALLA_RS11115
uniprot id: W0JNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

797299:HALLA RS05955
gene id: 797299:HALLA_RS05955
uniprot id: W0JKS1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS03435
gene id: 797299:HALLA_RS03435
uniprot id: W0JJV5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

797299:HALLA RS08695
gene id: 797299:HALLA_RS08695
uniprot id: W0JRW6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS19430
gene id: 797299:HALLA_RS19430
uniprot id: W0JZJ5
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05490
gene id: 797299:HALLA_RS05490
uniprot id: W0JQF6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797299:HALLA RS09175
gene id: 797299:HALLA_RS09175
uniprot id: W0JRP1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797299:HALLA RS05540
gene id: 797299:HALLA_RS05540
uniprot id: W0JKW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

797299:HALLA RS00345
gene id: 797299:HALLA_RS00345
uniprot id: W0JM32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797299:HALLA RS10760
gene id: 797299:HALLA_RS10760
uniprot id: W0JSD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

797299:HALLA RS03545
gene id: 797299:HALLA_RS03545
uniprot id: W0JPJ3
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

797299:HALLA RS10660
gene id: 797299:HALLA_RS10660
uniprot id: W0JQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

797299:HALLA RS07080
gene id: 797299:HALLA_RS07080
uniprot id: W0JR51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

797299:HALLA RS01330
gene id: 797299:HALLA_RS01330
uniprot id: W0JIQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

797299:HALLA RS10175
gene id: 797299:HALLA_RS10175
uniprot id: W0JRT8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02920
gene id: 797299:HALLA_RS02920
uniprot id: W0JNR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797299:HALLA RS03860
gene id: 797299:HALLA_RS03860
uniprot id: W0JNT6
names: Similarity
messages: Belongs to the peptidase S1C family.

797299:HALLA RS01940
gene id: 797299:HALLA_RS01940
uniprot id: W0JIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

797299:HALLA RS05275
gene id: 797299:HALLA_RS05275
uniprot id: W0JKC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00915
gene id: 797299:HALLA_RS00915
uniprot id: W0JIL2
names: Similarity
messages: Belongs to the peptidase S1C family.

797299:HALLA RS12110
gene id: 797299:HALLA_RS12110
uniprot id: W0JP47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

797299:HALLA RS06425
gene id: 797299:HALLA_RS06425
uniprot id: W0JKZ8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS08270
gene id: 797299:HALLA_RS08270
uniprot id: W0JM34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

797299:HALLA RS10635
gene id: 797299:HALLA_RS10635
uniprot id: W0JN03
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS08765
gene id: 797299:HALLA_RS08765
uniprot id: W0JLZ8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS06485
gene id: 797299:HALLA_RS06485
uniprot id: W0JQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

797299:HALLA RS05895
gene id: 797299:HALLA_RS05895
uniprot id: W0JKR2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10075
gene id: 797299:HALLA_RS10075
uniprot id: W0JRR8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

797299:HALLA RS14500
gene id: 797299:HALLA_RS14500
uniprot id: W0JVN2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS06245
gene id: 797299:HALLA_RS06245
uniprot id: W0JLC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS05780
gene id: 797299:HALLA_RS05780
uniprot id: W0JQP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797299:HALLA RS12165
gene id: 797299:HALLA_RS12165
uniprot id: W0JSU7
names: Similarity
messages: Belongs to the HypE family.

797299:HALLA RS08980
gene id: 797299:HALLA_RS08980
uniprot id: W0JRK9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

797299:HALLA RS16290
gene id: 797299:HALLA_RS16290
uniprot id: W0JWR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS02870
gene id: 797299:HALLA_RS02870
uniprot id: W0JJ82
names: Similarity
messages: Belongs to the TrpC family.

797299:HALLA RS05590
gene id: 797299:HALLA_RS05590
uniprot id: W0JQH9
names: Similarity
messages: Belongs to the peptidase S45 family.

797299:HALLA RS13310
gene id: 797299:HALLA_RS13310
uniprot id: W0JTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

797299:HALLA RS00745
gene id: 797299:HALLA_RS00745
uniprot id: W0JI67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS14075
gene id: 797299:HALLA_RS14075
uniprot id: W0JVV6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797299:HALLA RS11590
gene id: 797299:HALLA_RS11590
uniprot id: W0JSS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797299:HALLA RS03035
gene id: 797299:HALLA_RS03035
uniprot id: W0JJN8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

797299:HALLA RS00200
gene id: 797299:HALLA_RS00200
uniprot id: W0JM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS02495
gene id: 797299:HALLA_RS02495
uniprot id: W0JN17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS01780
gene id: 797299:HALLA_RS01780
uniprot id: W0JNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS03855
gene id: 797299:HALLA_RS03855
uniprot id: W0JJP0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

797299:HALLA RS13640
gene id: 797299:HALLA_RS13640
uniprot id: W0JPG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

797299:HALLA RS02370
gene id: 797299:HALLA_RS02370
uniprot id: W0JNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

797299:HALLA RS09525
gene id: 797299:HALLA_RS09525
uniprot id: W0JMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

797299:HALLA RS16430
gene id: 797299:HALLA_RS16430
uniprot id: W0JSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS13535
gene id: 797299:HALLA_RS13535
uniprot id: W0JTF5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797299:HALLA RS13605
gene id: 797299:HALLA_RS13605
uniprot id: W0JPT2
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

797299:HALLA RS06290
gene id: 797299:HALLA_RS06290
uniprot id: W0JQZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797299:HALLA RS14210
gene id: 797299:HALLA_RS14210
uniprot id: W0JR77
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS10215
gene id: 797299:HALLA_RS10215
uniprot id: W0JRU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797299:HALLA RS04235
gene id: 797299:HALLA_RS04235
uniprot id: W0JJW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

797299:HALLA RS19635
gene id: 797299:HALLA_RS19635
uniprot id: W0JV18
names: Similarity
messages: Belongs to the ComB family.

797299:HALLA RS03025
gene id: 797299:HALLA_RS03025
uniprot id: W0JNE8
names: Subunit
messages: Homodimer.

797299:HALLA RS03155
gene id: 797299:HALLA_RS03155
uniprot id: W0JJC6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

797299:HALLA RS18565
gene id: 797299:HALLA_RS18565
uniprot id: W0JUD2
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

797299:HALLA RS18080
gene id: 797299:HALLA_RS18080
uniprot id: W0JU15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797299:HALLA RS09275
gene id: 797299:HALLA_RS09275
uniprot id: W0JSA1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

797299:HALLA RS10875
gene id: 797299:HALLA_RS10875
uniprot id: W0JS63
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

797299:HALLA RS07260
gene id: 797299:HALLA_RS07260
uniprot id: W0JQN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

797299:HALLA RS00640
gene id: 797299:HALLA_RS00640
uniprot id: W0JMK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797299:HALLA RS18490
gene id: 797299:HALLA_RS18490
uniprot id: W0JYS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

797299:HALLA RS18060
gene id: 797299:HALLA_RS18060
uniprot id: W0JXZ4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

797299:HALLA RS04715
gene id: 797299:HALLA_RS04715
uniprot id: W0JKG6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

797299:HALLA RS01935
gene id: 797299:HALLA_RS01935
uniprot id: W0JN54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

797299:HALLA RS09300
gene id: 797299:HALLA_RS09300
uniprot id: W0JSA6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797299:HALLA RS08525
gene id: 797299:HALLA_RS08525
uniprot id: W0JLV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

797299:HALLA RS11585
gene id: 797299:HALLA_RS11585
uniprot id: W0JNT0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

797299:HALLA RS18170
gene id: 797299:HALLA_RS18170
uniprot id: W0JYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS19660
gene id: 797299:HALLA_RS19660
uniprot id: W0JYT3
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS03160
gene id: 797299:HALLA_RS03160
uniprot id: W0JNH0
names: Similarity
messages: Belongs to the eIF-2-alpha family.

797299:HALLA RS08530
gene id: 797299:HALLA_RS08530
uniprot id: W0JQZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

797299:HALLA RS01830
gene id: 797299:HALLA_RS01830
uniprot id: W0JIZ6
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS11665
gene id: 797299:HALLA_RS11665
uniprot id: W0JNX4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

797299:HALLA RS10805
gene id: 797299:HALLA_RS10805
uniprot id: W0JNE2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS08320
gene id: 797299:HALLA_RS08320
uniprot id: W0JRP3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05515
gene id: 797299:HALLA_RS05515
uniprot id: W0JKW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS00460
gene id: 797299:HALLA_RS00460
uniprot id: W0JM48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

797299:HALLA RS13520
gene id: 797299:HALLA_RS13520
uniprot id: W0JPR9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797299:HALLA RS12220
gene id: 797299:HALLA_RS12220
uniprot id: W0JSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797299:HALLA RS04295
gene id: 797299:HALLA_RS04295
uniprot id: W0JPW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

797299:HALLA RS10060
gene id: 797299:HALLA_RS10060
uniprot id: W0JN20
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

797299:HALLA RS01745
gene id: 797299:HALLA_RS01745
uniprot id: W0JIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797299:HALLA RS08570
gene id: 797299:HALLA_RS08570
uniprot id: W0JM86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS07685
gene id: 797299:HALLA_RS07685
uniprot id: W0JRE0
names: Similarity
messages: Belongs to the threonine synthase family.

797299:HALLA RS09120
gene id: 797299:HALLA_RS09120
uniprot id: W0JM89
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

797299:HALLA RS14140
gene id: 797299:HALLA_RS14140
uniprot id: W0JV39
names: Similarity
messages: Belongs to the RutC family.

797299:HALLA RS18715
gene id: 797299:HALLA_RS18715
uniprot id: W0JUH1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS13410
gene id: 797299:HALLA_RS13410
uniprot id: W0JTD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12495
gene id: 797299:HALLA_RS12495
uniprot id: W0JSZ4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14225
gene id: 797299:HALLA_RS14225
uniprot id: W0JRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

797299:HALLA RS01430
gene id: 797299:HALLA_RS01430
uniprot id: W0JMH0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS18615
gene id: 797299:HALLA_RS18615
uniprot id: W0JUE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS01340
gene id: 797299:HALLA_RS01340
uniprot id: W0JID9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797299:HALLA RS06450
gene id: 797299:HALLA_RS06450
uniprot id: W0JL02
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

797299:HALLA RS02450
gene id: 797299:HALLA_RS02450
uniprot id: W0JNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

797299:HALLA RS09520
gene id: 797299:HALLA_RS09520
uniprot id: W0JSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Vesicle
messages: gas vesicle

797299:HALLA RS11330
gene id: 797299:HALLA_RS11330
uniprot id: W0JSM9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS03870
gene id: 797299:HALLA_RS03870
uniprot id: W0JK38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS02640
gene id: 797299:HALLA_RS02640
uniprot id: W0JJD4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

797299:HALLA RS06020
gene id: 797299:HALLA_RS06020
uniprot id: W0JL85
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

797299:HALLA RS18340
gene id: 797299:HALLA_RS18340
uniprot id: W0JXW9
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797299:HALLA RS09705
gene id: 797299:HALLA_RS09705
uniprot id: W0JMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

797299:HALLA RS13100
gene id: 797299:HALLA_RS13100
uniprot id: W0JTF0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12340
gene id: 797299:HALLA_RS12340
uniprot id: W0JP80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

797299:HALLA RS01740
gene id: 797299:HALLA_RS01740
uniprot id: W0JN14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

797299:HALLA RS12820
gene id: 797299:HALLA_RS12820
uniprot id: W0JT45
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10420
gene id: 797299:HALLA_RS10420
uniprot id: W0JS77
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS01755
gene id: 797299:HALLA_RS01755
uniprot id: W0JNI9
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS17125
gene id: 797299:HALLA_RS17125
uniprot id: W0JXZ3
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

797299:HALLA RS09925
gene id: 797299:HALLA_RS09925
uniprot id: W0JMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797299:HALLA RS08790
gene id: 797299:HALLA_RS08790
uniprot id: W0JM03
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797299:HALLA RS08875
gene id: 797299:HALLA_RS08875
uniprot id: W0JM33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

797299:HALLA RS13870
gene id: 797299:HALLA_RS13870
uniprot id: W0JTM0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

797299:HALLA RS01660
gene id: 797299:HALLA_RS01660
uniprot id: W0JIW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

797299:HALLA RS17040
gene id: 797299:HALLA_RS17040
uniprot id: W0JXX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS05545
gene id: 797299:HALLA_RS05545
uniprot id: W0JPY5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

797299:HALLA RS08640
gene id: 797299:HALLA_RS08640
uniprot id: W0JRC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

797299:HALLA RS18950
gene id: 797299:HALLA_RS18950
uniprot id: W0JYC5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

797299:HALLA RS06110
gene id: 797299:HALLA_RS06110
uniprot id: W0JKU4
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

797299:HALLA RS06330
gene id: 797299:HALLA_RS06330
uniprot id: W0JQF0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

797299:HALLA RS17990
gene id: 797299:HALLA_RS17990
uniprot id: W0JTY6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

797299:HALLA RS09980
gene id: 797299:HALLA_RS09980
uniprot id: W0JN05
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS01855
gene id: 797299:HALLA_RS01855
uniprot id: W0JJ02
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797299:HALLA RS05075
gene id: 797299:HALLA_RS05075
uniprot id: W0JQ79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS08460
gene id: 797299:HALLA_RS08460
uniprot id: W0JR91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS11090
gene id: 797299:HALLA_RS11090
uniprot id: W0JNJ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797299:HALLA RS15165
gene id: 797299:HALLA_RS15165
uniprot id: W0JW15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

797299:HALLA RS03425
gene id: 797299:HALLA_RS03425
uniprot id: W0JNL2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS06325
gene id: 797299:HALLA_RS06325
uniprot id: W0JLD2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

797299:HALLA RS00155
gene id: 797299:HALLA_RS00155
uniprot id: W0JMV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS05880
gene id: 797299:HALLA_RS05880
uniprot id: W0JPX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

797299:HALLA RS11430
gene id: 797299:HALLA_RS11430
uniprot id: W0JSH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

797299:HALLA RS10985
gene id: 797299:HALLA_RS10985
uniprot id: W0JS87
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

797299:HALLA RS13815
gene id: 797299:HALLA_RS13815
uniprot id: W0JUC1
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

797299:HALLA RS10130
gene id: 797299:HALLA_RS10130
uniprot id: W0JSN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS04705
gene id: 797299:HALLA_RS04705
uniprot id: W0JP62
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

797299:HALLA RS01720
gene id: 797299:HALLA_RS01720
uniprot id: W0JIJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

797299:HALLA RS08260
gene id: 797299:HALLA_RS08260
uniprot id: W0JQU4
names: Subcellular Location Annotation
messages: Cell membrane

797299:HALLA RS16710
gene id: 797299:HALLA_RS16710
uniprot id: W0JT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797299:HALLA RS02525
gene id: 797299:HALLA_RS02525
uniprot id: W0JNX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00580
gene id: 797299:HALLA_RS00580
uniprot id: W0JMJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

797299:HALLA RS10945
gene id: 797299:HALLA_RS10945
uniprot id: W0JNG8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

797299:HALLA RS18825
gene id: 797299:HALLA_RS18825
uniprot id: W0JZ22
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS16435
gene id: 797299:HALLA_RS16435
uniprot id: W0JWM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS00830
gene id: 797299:HALLA_RS00830
uniprot id: W0JIJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

797299:HALLA RS08215
gene id: 797299:HALLA_RS08215
uniprot id: W0JM25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797299:HALLA RS05405
gene id: 797299:HALLA_RS05405
uniprot id: W0JQD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

797299:HALLA RS00440
gene id: 797299:HALLA_RS00440
uniprot id: W0JN07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS04070
gene id: 797299:HALLA_RS04070
uniprot id: W0JPA1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

797299:HALLA RS02915
gene id: 797299:HALLA_RS02915
uniprot id: W0JJM0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS08590
gene id: 797299:HALLA_RS08590
uniprot id: W0JM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS10235
gene id: 797299:HALLA_RS10235
uniprot id: W0JMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

797299:HALLA RS01955
gene id: 797299:HALLA_RS01955
uniprot id: W0JJ21
names: Similarity
messages: Belongs to the thymidylate kinase family.

797299:HALLA RS12330
gene id: 797299:HALLA_RS12330
uniprot id: W0JSX2
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

797299:HALLA RS09685
gene id: 797299:HALLA_RS09685
uniprot id: W0JRW8
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797299:HALLA RS11880
gene id: 797299:HALLA_RS11880
uniprot id: W0JNP0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

797299:HALLA RS10375
gene id: 797299:HALLA_RS10375
uniprot id: W0JRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797299:HALLA RS10700
gene id: 797299:HALLA_RS10700
uniprot id: W0JSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

797299:HALLA RS08500
gene id: 797299:HALLA_RS08500
uniprot id: W0JRS8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00475
gene id: 797299:HALLA_RS00475
uniprot id: W0JMI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS14175
gene id: 797299:HALLA_RS14175
uniprot id: W0JRI4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14050
gene id: 797299:HALLA_RS14050
uniprot id: W0JQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

797299:HALLA RS18630
gene id: 797299:HALLA_RS18630
uniprot id: W0JY44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10225
gene id: 797299:HALLA_RS10225
uniprot id: W0JN47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS09555
gene id: 797299:HALLA_RS09555
uniprot id: W0JMS7
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

797299:HALLA RS19715
gene id: 797299:HALLA_RS19715
uniprot id: W0JV74
names: Similarity
messages: Belongs to the HerA family.

797299:HALLA RS09145
gene id: 797299:HALLA_RS09145
uniprot id: W0JM90
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS03005
gene id: 797299:HALLA_RS03005
uniprot id: W0JJN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

797299:HALLA RS02290
gene id: 797299:HALLA_RS02290
uniprot id: W0JIV7
names: Similarity
messages: Belongs to the peptidase S49 family.

797299:HALLA RS09365
gene id: 797299:HALLA_RS09365
uniprot id: W0JMQ1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

797299:HALLA RS10625
gene id: 797299:HALLA_RS10625
uniprot id: W0JNB6
names: Similarity
messages: Belongs to the UPF0212 family.

797299:HALLA RS13085
gene id: 797299:HALLA_RS13085
uniprot id: W0JT82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS08625
gene id: 797299:HALLA_RS08625
uniprot id: W0JR19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

797299:HALLA RS05855
gene id: 797299:HALLA_RS05855
uniprot id: W0JQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797299:HALLA RS14035
gene id: 797299:HALLA_RS14035
uniprot id: W0JPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

797299:HALLA RS14525
gene id: 797299:HALLA_RS14525
uniprot id: W0JVN6
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.

797299:HALLA RS01595
gene id: 797299:HALLA_RS01595
uniprot id: W0JIV0
names: Similarity
messages: Belongs to the Ahb/Nir family.

797299:HALLA RS04885
gene id: 797299:HALLA_RS04885
uniprot id: W0JKJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

797299:HALLA RS10335
gene id: 797299:HALLA_RS10335
uniprot id: W0JS64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

797299:HALLA RS10655
gene id: 797299:HALLA_RS10655
uniprot id: W0JUZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

797299:HALLA RS07675
gene id: 797299:HALLA_RS07675
uniprot id: W0JQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

797299:HALLA RS15235
gene id: 797299:HALLA_RS15235
uniprot id: W0JVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797299:HALLA RS12710
gene id: 797299:HALLA_RS12710
uniprot id: W0JPE2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS06100
gene id: 797299:HALLA_RS06100
uniprot id: W0JL99
names: Similarity
messages: Belongs to the CutA family.

797299:HALLA RS08425
gene id: 797299:HALLA_RS08425
uniprot id: W0JRR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797299:HALLA RS00175
gene id: 797299:HALLA_RS00175
uniprot id: W0JM09
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797299:HALLA RS10820
gene id: 797299:HALLA_RS10820
uniprot id: W0JSY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

797299:HALLA RS12815
gene id: 797299:HALLA_RS12815
uniprot id: W0JP30
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797299:HALLA RS11240
gene id: 797299:HALLA_RS11240
uniprot id: W0JSD5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

797299:HALLA RS18605
gene id: 797299:HALLA_RS18605
uniprot id: W0JY36
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

797299:HALLA RS08265
gene id: 797299:HALLA_RS08265
uniprot id: W0JRN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

797299:HALLA RS03370
gene id: 797299:HALLA_RS03370
uniprot id: W0JNK3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS11280
gene id: 797299:HALLA_RS11280
uniprot id: W0JSM1
names: Similarity
messages: Belongs to the UPF0215 family.

797299:HALLA RS04815
gene id: 797299:HALLA_RS04815
uniprot id: W0JQ32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

797299:HALLA RS02105
gene id: 797299:HALLA_RS02105
uniprot id: W0JNQ0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

797299:HALLA RS15820
gene id: 797299:HALLA_RS15820
uniprot id: W0JWE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS00500
gene id: 797299:HALLA_RS00500
uniprot id: W0JMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797299:HALLA RS07310
gene id: 797299:HALLA_RS07310
uniprot id: W0JQP3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

797299:HALLA RS05870
gene id: 797299:HALLA_RS05870
uniprot id: W0JKQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS09490
gene id: 797299:HALLA_RS09490
uniprot id: W0JSD8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

797299:HALLA RS09390
gene id: 797299:HALLA_RS09390
uniprot id: W0JSC1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

797299:HALLA RS03525
gene id: 797299:HALLA_RS03525
uniprot id: W0JJI3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

797299:HALLA RS03310
gene id: 797299:HALLA_RS03310
uniprot id: W0JNW8
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

797299:HALLA RS13710
gene id: 797299:HALLA_RS13710
uniprot id: W0JPV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS06410
gene id: 797299:HALLA_RS06410
uniprot id: W0JR13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

797299:HALLA RS05620
gene id: 797299:HALLA_RS05620
uniprot id: W0JKY4
names: Similarity
messages: Belongs to the UPF0179 family.

797299:HALLA RS15355
gene id: 797299:HALLA_RS15355
uniprot id: W0JRZ3
names: Similarity
messages: Belongs to the group II decarboxylase family.

797299:HALLA RS13340
gene id: 797299:HALLA_RS13340
uniprot id: W0JU41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS05185
gene id: 797299:HALLA_RS05185
uniprot id: W0JKP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

797299:HALLA RS19695
gene id: 797299:HALLA_RS19695
uniprot id: W0JV70
names: Similarity
messages: Belongs to the group II decarboxylase family.

797299:HALLA RS05525
gene id: 797299:HALLA_RS05525
uniprot id: W0JKH2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS13055
gene id: 797299:HALLA_RS13055
uniprot id: W0JP63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

797299:HALLA RS04030
gene id: 797299:HALLA_RS04030
uniprot id: W0JNW5
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS00620
gene id: 797299:HALLA_RS00620
uniprot id: W0JN41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797299:HALLA RS19030
gene id: 797299:HALLA_RS19030
uniprot id: W0JUR9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

797299:HALLA RS14020
gene id: 797299:HALLA_RS14020
uniprot id: W0JPZ8
names: Similarity
messages: Belongs to the IMPACT family.

797299:HALLA RS08820
gene id: 797299:HALLA_RS08820
uniprot id: W0JRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

797299:HALLA RS12810
gene id: 797299:HALLA_RS12810
uniprot id: W0JTA6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797299:HALLA RS15455
gene id: 797299:HALLA_RS15455
uniprot id: W0JS15
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS09415
gene id: 797299:HALLA_RS09415
uniprot id: W0JSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

797299:HALLA RS05830
gene id: 797299:HALLA_RS05830
uniprot id: W0JQQ7
names: Similarity
messages: Belongs to the FUN14 family.

797299:HALLA RS09905
gene id: 797299:HALLA_RS09905
uniprot id: W0JRP5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

797299:HALLA RS11495
gene id: 797299:HALLA_RS11495
uniprot id: W0JT94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS10315
gene id: 797299:HALLA_RS10315
uniprot id: W0JMU2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797299:HALLA RS10425
gene id: 797299:HALLA_RS10425
uniprot id: W0JMW2
names: Similarity
messages: Belongs to the UPF0284 family.

797299:HALLA RS09180
gene id: 797299:HALLA_RS09180
uniprot id: W0JM95
names: Similarity
messages: Belongs to the LarC family.

797299:HALLA RS06155
gene id: 797299:HALLA_RS06155
uniprot id: W0JKV0
names: Similarity
messages: Belongs to the Dps family.

797299:HALLA RS13345
gene id: 797299:HALLA_RS13345
uniprot id: W0JPN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

797299:HALLA RS13765
gene id: 797299:HALLA_RS13765
uniprot id: W0JUA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS15230
gene id: 797299:HALLA_RS15230
uniprot id: W0JW25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS08610
gene id: 797299:HALLA_RS08610
uniprot id: W0JRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

797299:HALLA RS05825
gene id: 797299:HALLA_RS05825
uniprot id: W0JPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

797299:HALLA RS06385
gene id: 797299:HALLA_RS06385
uniprot id: W0JR07
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Belongs to the isochorismate synthase family.

797299:HALLA RS07510
gene id: 797299:HALLA_RS07510
uniprot id: W0JLR3
names: Subcellular Location Annotation
messages: Cell membrane

797299:HALLA RS14910
gene id: 797299:HALLA_RS14910
uniprot id: W0JRP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS05220
gene id: 797299:HALLA_RS05220
uniprot id: W0JPS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS09080
gene id: 797299:HALLA_RS09080
uniprot id: W0JMK9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

797299:HALLA RS12010
gene id: 797299:HALLA_RS12010
uniprot id: W0JST0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

797299:HALLA RS10110
gene id: 797299:HALLA_RS10110
uniprot id: W0JN30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS01525
gene id: 797299:HALLA_RS01525
uniprot id: W0JIG2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797299:HALLA RS19230
gene id: 797299:HALLA_RS19230
uniprot id: W0JYR0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS09760
gene id: 797299:HALLA_RS09760
uniprot id: W0JRY0
names: Similarity
messages: Belongs to the HypE family.

797299:HALLA RS03050
gene id: 797299:HALLA_RS03050
uniprot id: W0JNF4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

797299:HALLA RS13275
gene id: 797299:HALLA_RS13275
uniprot id: W0JP95
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS13285
gene id: 797299:HALLA_RS13285
uniprot id: W0JU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

797299:HALLA RS16990
gene id: 797299:HALLA_RS16990
uniprot id: W0JT80
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS15280
gene id: 797299:HALLA_RS15280
uniprot id: W0JRX7
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS01510
gene id: 797299:HALLA_RS01510
uniprot id: W0JIT7
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS18235
gene id: 797299:HALLA_RS18235
uniprot id: W0JU39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

797299:HALLA RS18050
gene id: 797299:HALLA_RS18050
uniprot id: W0JYJ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797299:HALLA RS17430
gene id: 797299:HALLA_RS17430
uniprot id: W0JTN1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02510
gene id: 797299:HALLA_RS02510
uniprot id: W0JNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797299:HALLA RS09205
gene id: 797299:HALLA_RS09205
uniprot id: W0JMM5
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

797299:HALLA RS03410
gene id: 797299:HALLA_RS03410
uniprot id: W0JJV1
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

797299:HALLA RS08000
gene id: 797299:HALLA_RS08000
uniprot id: W0JRI9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10980
gene id: 797299:HALLA_RS10980
uniprot id: W0JN64
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797299:HALLA RS03185
gene id: 797299:HALLA_RS03185
uniprot id: W0JNH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

797299:HALLA RS19405
gene id: 797299:HALLA_RS19405
uniprot id: W0JZJ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

797299:HALLA RS19540
gene id: 797299:HALLA_RS19540
uniprot id: W0JV33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS03840
gene id: 797299:HALLA_RS03840
uniprot id: W0JPP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

797299:HALLA RS02405
gene id: 797299:HALLA_RS02405
uniprot id: W0JJ90
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS14555
gene id: 797299:HALLA_RS14555
uniprot id: W0JVG3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS03780
gene id: 797299:HALLA_RS03780
uniprot id: W0JPN5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12995
gene id: 797299:HALLA_RS12995
uniprot id: W0JP59
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

797299:HALLA RS00725
gene id: 797299:HALLA_RS00725
uniprot id: W0JM87
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS18895
gene id: 797299:HALLA_RS18895
uniprot id: W0JUL5
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

797299:HALLA RS11265
gene id: 797299:HALLA_RS11265
uniprot id: W0JSE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS13070
gene id: 797299:HALLA_RS13070
uniprot id: W0JPJ6
names: Similarity
messages: Belongs to the SUI1 family.

797299:HALLA RS18990
gene id: 797299:HALLA_RS18990
uniprot id: W0JUN9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS12120
gene id: 797299:HALLA_RS12120
uniprot id: W0JNS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

797299:HALLA RS13300
gene id: 797299:HALLA_RS13300
uniprot id: W0JPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

797299:HALLA RS02400
gene id: 797299:HALLA_RS02400
uniprot id: W0JNV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

797299:HALLA RS07130
gene id: 797299:HALLA_RS07130
uniprot id: W0JR61
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797299:HALLA RS13475
gene id: 797299:HALLA_RS13475
uniprot id: W0JTL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

797299:HALLA RS08795
gene id: 797299:HALLA_RS08795
uniprot id: W0JR53
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

797299:HALLA RS04125
gene id: 797299:HALLA_RS04125
uniprot id: W0JPB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS12180
gene id: 797299:HALLA_RS12180
uniprot id: W0JT23
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797299:HALLA RS04145
gene id: 797299:HALLA_RS04145
uniprot id: W0JK87
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS19425
gene id: 797299:HALLA_RS19425
uniprot id: W0JYN5
names: Similarity
messages: Belongs to the NAD synthetase family.

797299:HALLA RS19685
gene id: 797299:HALLA_RS19685
uniprot id: W0JYT8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS04675
gene id: 797299:HALLA_RS04675
uniprot id: W0JK13
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797299:HALLA RS11010
gene id: 797299:HALLA_RS11010
uniprot id: W0JS92
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS17955
gene id: 797299:HALLA_RS17955
uniprot id: W0JTZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

797299:HALLA RS12950
gene id: 797299:HALLA_RS12950
uniprot id: W0JTZ6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797299:HALLA RS11695
gene id: 797299:HALLA_RS11695
uniprot id: W0JTF1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797299:HALLA RS10140
gene id: 797299:HALLA_RS10140
uniprot id: W0JS38
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

797299:HALLA RS09215
gene id: 797299:HALLA_RS09215
uniprot id: W0JM99
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS18400
gene id: 797299:HALLA_RS18400
uniprot id: W0JY69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS05380
gene id: 797299:HALLA_RS05380
uniprot id: W0JQD4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

797299:HALLA RS03120
gene id: 797299:HALLA_RS03120
uniprot id: W0JNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS07110
gene id: 797299:HALLA_RS07110
uniprot id: W0JLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797299:HALLA RS13985
gene id: 797299:HALLA_RS13985
uniprot id: W0JTP1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS18415
gene id: 797299:HALLA_RS18415
uniprot id: W0JYR5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797299:HALLA RS05055
gene id: 797299:HALLA_RS05055
uniprot id: W0JKL9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

797299:HALLA RS10005
gene id: 797299:HALLA_RS10005
uniprot id: W0JS20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797299:HALLA RS03220
gene id: 797299:HALLA_RS03220
uniprot id: W0JPD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

797299:HALLA RS18905
gene id: 797299:HALLA_RS18905
uniprot id: W0JUJ8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

797299:HALLA RS09455
gene id: 797299:HALLA_RS09455
uniprot id: W0JRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS10710
gene id: 797299:HALLA_RS10710
uniprot id: W0JS30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS04760
gene id: 797299:HALLA_RS04760
uniprot id: W0JQ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797299:HALLA RS11275
gene id: 797299:HALLA_RS11275
uniprot id: W0JNM5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

797299:HALLA RS16320
gene id: 797299:HALLA_RS16320
uniprot id: W0JSN3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02930
gene id: 797299:HALLA_RS02930
uniprot id: W0JND5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS08560
gene id: 797299:HALLA_RS08560
uniprot id: W0JR04
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

797299:HALLA RS07560
gene id: 797299:HALLA_RS07560
uniprot id: W0JLS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

797299:HALLA RS08335
gene id: 797299:HALLA_RS08335
uniprot id: W0JLR1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS00730
gene id: 797299:HALLA_RS00730
uniprot id: W0JN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

797299:HALLA RS09090
gene id: 797299:HALLA_RS09090
uniprot id: W0JM85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

797299:HALLA RS08580
gene id: 797299:HALLA_RS08580
uniprot id: W0JLW0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

797299:HALLA RS08485
gene id: 797299:HALLA_RS08485
uniprot id: W0JR95
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS05770
gene id: 797299:HALLA_RS05770
uniprot id: W0JKP2
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

797299:HALLA RS13090
gene id: 797299:HALLA_RS13090
uniprot id: W0JU10
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS14375
gene id: 797299:HALLA_RS14375
uniprot id: W0JRN0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797299:HALLA RS13010
gene id: 797299:HALLA_RS13010
uniprot id: W0JT73
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797299:HALLA RS11390
gene id: 797299:HALLA_RS11390
uniprot id: W0JSG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

797299:HALLA RS12690
gene id: 797299:HALLA_RS12690
uniprot id: W0JT92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

797299:HALLA RS12965
gene id: 797299:HALLA_RS12965
uniprot id: W0JP54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

797299:HALLA RS08535
gene id: 797299:HALLA_RS08535
uniprot id: W0JRT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS17670
gene id: 797299:HALLA_RS17670
uniprot id: W0JXG7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS15125
gene id: 797299:HALLA_RS15125
uniprot id: W0JVS6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10300
gene id: 797299:HALLA_RS10300
uniprot id: W0JSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797299:HALLA RS02520
gene id: 797299:HALLA_RS02520
uniprot id: W0JN22
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10080
gene id: 797299:HALLA_RS10080
uniprot id: W0JSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797299:HALLA RS08385
gene id: 797299:HALLA_RS08385
uniprot id: W0JR79
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03110
gene id: 797299:HALLA_RS03110
uniprot id: W0JPB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10765
gene id: 797299:HALLA_RS10765
uniprot id: W0JN24
names: Similarity
messages: Belongs to the peptidase S9C family.

797299:HALLA RS05370
gene id: 797299:HALLA_RS05370
uniprot id: W0JKE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797299:HALLA RS16305
gene id: 797299:HALLA_RS16305
uniprot id: W0JXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS04020
gene id: 797299:HALLA_RS04020
uniprot id: W0JP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

797299:HALLA RS18935
gene id: 797299:HALLA_RS18935
uniprot id: W0JZ59
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797299:HALLA RS01470
gene id: 797299:HALLA_RS01470
uniprot id: W0JIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

797299:HALLA RS11255
gene id: 797299:HALLA_RS11255
uniprot id: W0JSL5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

797299:HALLA RS04055
gene id: 797299:HALLA_RS04055
uniprot id: W0JNW9
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797299:HALLA RS06145
gene id: 797299:HALLA_RS06145
uniprot id: W0JQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

797299:HALLA RS19625
gene id: 797299:HALLA_RS19625
uniprot id: W0JV55
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

797299:HALLA RS10065
gene id: 797299:HALLA_RS10065
uniprot id: W0JS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

797299:HALLA RS18485
gene id: 797299:HALLA_RS18485
uniprot id: W0JY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

797299:HALLA RS11190
gene id: 797299:HALLA_RS11190
uniprot id: W0JT42
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797299:HALLA RS15770
gene id: 797299:HALLA_RS15770
uniprot id: W0JSI2
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS10960
gene id: 797299:HALLA_RS10960
uniprot id: W0JS81
names: Similarity
messages: Belongs to the arginase family.

797299:HALLA RS06775
gene id: 797299:HALLA_RS06775
uniprot id: W0JL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

797299:HALLA RS02430
gene id: 797299:HALLA_RS02430
uniprot id: W0JJ96
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS07165
gene id: 797299:HALLA_RS07165
uniprot id: W0JQL8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS13120
gene id: 797299:HALLA_RS13120
uniprot id: W0JU14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

797299:HALLA RS01970
gene id: 797299:HALLA_RS01970
uniprot id: W0JMR5
names: Function
messages: Part of a potassium transport system.

797299:HALLA RS19335
gene id: 797299:HALLA_RS19335
uniprot id: W0JYL9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS16335
gene id: 797299:HALLA_RS16335
uniprot id: W0JSW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797299:HALLA RS17915
gene id: 797299:HALLA_RS17915
uniprot id: W0JXW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS08565
gene id: 797299:HALLA_RS08565
uniprot id: W0JRT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS17210
gene id: 797299:HALLA_RS17210
uniprot id: W0JTI5
names: Similarity
messages: Belongs to the GbsR family.

797299:HALLA RS08600
gene id: 797299:HALLA_RS08600
uniprot id: W0JLW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS18195
gene id: 797299:HALLA_RS18195
uniprot id: W0JYL8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797299:HALLA RS10050
gene id: 797299:HALLA_RS10050
uniprot id: W0JRR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

797299:HALLA RS14425
gene id: 797299:HALLA_RS14425
uniprot id: W0JRQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS16635
gene id: 797299:HALLA_RS16635
uniprot id: W0JT52
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

797299:HALLA RS14480
gene id: 797299:HALLA_RS14480
uniprot id: W0JRG0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS08800
gene id: 797299:HALLA_RS08800
uniprot id: W0JRY8
names: Similarity
messages: Belongs to the PEPCase type 1 family.

797299:HALLA RS07630
gene id: 797299:HALLA_RS07630
uniprot id: W0JQV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

797299:HALLA RS12405
gene id: 797299:HALLA_RS12405
uniprot id: W0JT54
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10045
gene id: 797299:HALLA_RS10045
uniprot id: W0JMP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS08220
gene id: 797299:HALLA_RS08220
uniprot id: W0JR52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797299:HALLA RS00360
gene id: 797299:HALLA_RS00360
uniprot id: W0JMG4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

797299:HALLA RS10705
gene id: 797299:HALLA_RS10705
uniprot id: W0JN13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797299:HALLA RS01775
gene id: 797299:HALLA_RS01775
uniprot id: W0JMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS01945
gene id: 797299:HALLA_RS01945
uniprot id: W0JMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797299:HALLA RS01860
gene id: 797299:HALLA_RS01860
uniprot id: W0JN37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797299:HALLA RS05745
gene id: 797299:HALLA_RS05745
uniprot id: W0JKN8
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

797299:HALLA RS10270
gene id: 797299:HALLA_RS10270
uniprot id: W0JRV2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

797299:HALLA RS19200
gene id: 797299:HALLA_RS19200
uniprot id: W0JUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797299:HALLA RS05335
gene id: 797299:HALLA_RS05335
uniprot id: W0JKS6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

797299:HALLA RS00455
gene id: 797299:HALLA_RS00455
uniprot id: W0JI23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS02710
gene id: 797299:HALLA_RS02710
uniprot id: W0JN61
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

797299:HALLA RS04690
gene id: 797299:HALLA_RS04690
uniprot id: W0JKG1
names: Similarity
messages: Belongs to the DtxR/MntR family.

797299:HALLA RS06185
gene id: 797299:HALLA_RS06185
uniprot id: W0JQ19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS14735
gene id: 797299:HALLA_RS14735
uniprot id: W0JRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS10445
gene id: 797299:HALLA_RS10445
uniprot id: W0JS82
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS08825
gene id: 797299:HALLA_RS08825
uniprot id: W0JM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

797299:HALLA RS08705
gene id: 797299:HALLA_RS08705
uniprot id: W0JRD4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797299:HALLA RS07125
gene id: 797299:HALLA_RS07125
uniprot id: W0JQA3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

797299:HALLA RS16265
gene id: 797299:HALLA_RS16265
uniprot id: W0JWR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

797299:HALLA RS04650
gene id: 797299:HALLA_RS04650
uniprot id: W0JK07
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS12760
gene id: 797299:HALLA_RS12760
uniprot id: W0JP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

797299:HALLA RS03775
gene id: 797299:HALLA_RS03775
uniprot id: W0JNS0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797299:HALLA RS16850
gene id: 797299:HALLA_RS16850
uniprot id: W0JX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS15225
gene id: 797299:HALLA_RS15225
uniprot id: W0JVU8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797299:HALLA RS18610
gene id: 797299:HALLA_RS18610
uniprot id: W0JYW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS09270
gene id: 797299:HALLA_RS09270
uniprot id: W0JRE8
names: Similarity
messages: Belongs to the peptidase C56 family.

797299:HALLA RS05695
gene id: 797299:HALLA_RS05695
uniprot id: W0JPS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797299:HALLA RS08860
gene id: 797299:HALLA_RS08860
uniprot id: W0JS00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

797299:HALLA RS19350
gene id: 797299:HALLA_RS19350
uniprot id: W0JUU9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS02415
gene id: 797299:HALLA_RS02415
uniprot id: W0JIX6
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

797299:HALLA RS11225
gene id: 797299:HALLA_RS11225
uniprot id: W0JNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

797299:HALLA RS01170
gene id: 797299:HALLA_RS01170
uniprot id: W0JMD4
names: Similarity
messages: Belongs to the HerA family.

797299:HALLA RS07370
gene id: 797299:HALLA_RS07370
uniprot id: W0JQE7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797299:HALLA RS05555
gene id: 797299:HALLA_RS05555
uniprot id: W0JPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

797299:HALLA RS10070
gene id: 797299:HALLA_RS10070
uniprot id: W0JMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS08835
gene id: 797299:HALLA_RS08835
uniprot id: W0JRZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

797299:HALLA RS02505
gene id: 797299:HALLA_RS02505
uniprot id: W0JJB0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

797299:HALLA RS11660
gene id: 797299:HALLA_RS11660
uniprot id: W0JTE6
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797299:HALLA RS16965
gene id: 797299:HALLA_RS16965
uniprot id: W0JX99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS07605
gene id: 797299:HALLA_RS07605
uniprot id: W0JLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS00530
gene id: 797299:HALLA_RS00530
uniprot id: W0JI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS18675
gene id: 797299:HALLA_RS18675
uniprot id: W0JUE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS14765
gene id: 797299:HALLA_RS14765
uniprot id: W0JWB7
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS01765
gene id: 797299:HALLA_RS01765
uniprot id: W0JN19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS18625
gene id: 797299:HALLA_RS18625
uniprot id: W0JUC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS15940
gene id: 797299:HALLA_RS15940
uniprot id: W0JSM2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797299:HALLA RS16970
gene id: 797299:HALLA_RS16970
uniprot id: W0JT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS03295
gene id: 797299:HALLA_RS03295
uniprot id: W0JPF1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

797299:HALLA RS05390
gene id: 797299:HALLA_RS05390
uniprot id: W0JPV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS14965
gene id: 797299:HALLA_RS14965
uniprot id: W0JVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS06165
gene id: 797299:HALLA_RS06165
uniprot id: W0JQW8
names: Similarity
messages: Belongs to the GARS family.

797299:HALLA RS10305
gene id: 797299:HALLA_RS10305
uniprot id: W0JN62
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS01530
gene id: 797299:HALLA_RS01530
uniprot id: W0JMI6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797299:HALLA RS13365
gene id: 797299:HALLA_RS13365
uniprot id: W0JU44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

797299:HALLA RS02470
gene id: 797299:HALLA_RS02470
uniprot id: W0JN12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS03600
gene id: 797299:HALLA_RS03600
uniprot id: W0JPK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

797299:HALLA RS09920
gene id: 797299:HALLA_RS09920
uniprot id: W0JS09
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

797299:HALLA RS13515
gene id: 797299:HALLA_RS13515
uniprot id: W0JU69
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797299:HALLA RS04665
gene id: 797299:HALLA_RS04665
uniprot id: W0JKF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

797299:HALLA RS00105
gene id: 797299:HALLA_RS00105
uniprot id: W0JI79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

797299:HALLA RS01195
gene id: 797299:HALLA_RS01195
uniprot id: W0JMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

797299:HALLA RS17685
gene id: 797299:HALLA_RS17685
uniprot id: W0JXP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS05550
gene id: 797299:HALLA_RS05550
uniprot id: W0JKH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

797299:HALLA RS14645
gene id: 797299:HALLA_RS14645
uniprot id: W0JRI6
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS11655
gene id: 797299:HALLA_RS11655
uniprot id: W0JSN2
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797299:HALLA RS17375
gene id: 797299:HALLA_RS17375
uniprot id: W0JTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS13470
gene id: 797299:HALLA_RS13470
uniprot id: W0JPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

797299:HALLA RS01550
gene id: 797299:HALLA_RS01550
uniprot id: W0JMX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797299:HALLA RS09665
gene id: 797299:HALLA_RS09665
uniprot id: W0JMH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

797299:HALLA RS10155
gene id: 797299:HALLA_RS10155
uniprot id: W0JSN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

797299:HALLA RS11860
gene id: 797299:HALLA_RS11860
uniprot id: W0JP10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

797299:HALLA RS16450
gene id: 797299:HALLA_RS16450
uniprot id: W0JWV6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS04750
gene id: 797299:HALLA_RS04750
uniprot id: W0JK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797299:HALLA RS08995
gene id: 797299:HALLA_RS08995
uniprot id: W0JS57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

797299:HALLA RS15495
gene id: 797299:HALLA_RS15495
uniprot id: W0JSC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

797299:HALLA RS10605
gene id: 797299:HALLA_RS10605
uniprot id: W0JSB0
names: Similarity
messages: Belongs to the acylphosphatase family.

797299:HALLA RS10125
gene id: 797299:HALLA_RS10125
uniprot id: W0JRS9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

797299:HALLA RS09720
gene id: 797299:HALLA_RS09720
uniprot id: W0JRL6
names: Similarity
messages: Belongs to the UPF0045 family.

797299:HALLA RS16975
gene id: 797299:HALLA_RS16975
uniprot id: W0JX26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS02905
gene id: 797299:HALLA_RS02905
uniprot id: W0JND0
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

797299:HALLA RS14460
gene id: 797299:HALLA_RS14460
uniprot id: W0JVE1
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

797299:HALLA RS17640
gene id: 797299:HALLA_RS17640
uniprot id: W0JXN7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS18685
gene id: 797299:HALLA_RS18685
uniprot id: W0JYY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS18155
gene id: 797299:HALLA_RS18155
uniprot id: W0JY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS02075
gene id: 797299:HALLA_RS02075
uniprot id: W0JMT4
names: Similarity
messages: Belongs to the PspA/IM30 family.

797299:HALLA RS14630
gene id: 797299:HALLA_RS14630
uniprot id: W0JVH8
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03280
gene id: 797299:HALLA_RS03280
uniprot id: W0JNW6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797299:HALLA RS18495
gene id: 797299:HALLA_RS18495
uniprot id: W0JUB1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02725
gene id: 797299:HALLA_RS02725
uniprot id: W0JNJ5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS12380
gene id: 797299:HALLA_RS12380
uniprot id: W0JT51
names: Similarity
messages: Belongs to the AAA ATPase family.

797299:HALLA RS13730
gene id: 797299:HALLA_RS13730
uniprot id: W0JUA5
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS07690
gene id: 797299:HALLA_RS07690
uniprot id: W0JLU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

797299:HALLA RS07185
gene id: 797299:HALLA_RS07185
uniprot id: W0JLK8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS08440
gene id: 797299:HALLA_RS08440
uniprot id: W0JLT4
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

797299:HALLA RS18200
gene id: 797299:HALLA_RS18200
uniprot id: W0JU43
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797299:HALLA RS17185
gene id: 797299:HALLA_RS17185
uniprot id: W0JY06
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797299:HALLA RS13805
gene id: 797299:HALLA_RS13805
uniprot id: W0JPJ5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

797299:HALLA RS12865
gene id: 797299:HALLA_RS12865
uniprot id: W0JP41
names: Similarity
messages: Belongs to the SUI1 family.

797299:HALLA RS10055
gene id: 797299:HALLA_RS10055
uniprot id: W0JSL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

797299:HALLA RS17070
gene id: 797299:HALLA_RS17070
uniprot id: W0JXB9
names: Similarity
messages: Belongs to the TPP enzyme family.

797299:HALLA RS08620
gene id: 797299:HALLA_RS08620
uniprot id: W0JLX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

797299:HALLA RS18075
gene id: 797299:HALLA_RS18075
uniprot id: W0JYJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797299:HALLA RS13740
gene id: 797299:HALLA_RS13740
uniprot id: W0JTR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

797299:HALLA RS08850
gene id: 797299:HALLA_RS08850
uniprot id: W0JM14
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

797299:HALLA RS12260
gene id: 797299:HALLA_RS12260
uniprot id: W0JT34
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00585
gene id: 797299:HALLA_RS00585
uniprot id: W0JI43
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

797299:HALLA RS07120
gene id: 797299:HALLA_RS07120
uniprot id: W0JL37
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

797299:HALLA RS13510
gene id: 797299:HALLA_RS13510
uniprot id: W0JTF3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS10585
gene id: 797299:HALLA_RS10585
uniprot id: W0JMZ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS00450
gene id: 797299:HALLA_RS00450
uniprot id: W0JMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS10435
gene id: 797299:HALLA_RS10435
uniprot id: W0JSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

797299:HALLA RS07060
gene id: 797299:HALLA_RS07060
uniprot id: W0JLI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

797299:HALLA RS08550
gene id: 797299:HALLA_RS08550
uniprot id: W0JRA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

797299:HALLA RS00270
gene id: 797299:HALLA_RS00270
uniprot id: W0JHZ5
names: Similarity
messages: Belongs to the HMBS family.

797299:HALLA RS03720
gene id: 797299:HALLA_RS03720
uniprot id: W0JJL4
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

797299:HALLA RS04770
gene id: 797299:HALLA_RS04770
uniprot id: W0JKH4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS07340
gene id: 797299:HALLA_RS07340
uniprot id: W0JL79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS14960
gene id: 797299:HALLA_RS14960
uniprot id: W0JRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS07415
gene id: 797299:HALLA_RS07415
uniprot id: W0JL96
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797299:HALLA RS08330
gene id: 797299:HALLA_RS08330
uniprot id: W0JR70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

797299:HALLA RS12335
gene id: 797299:HALLA_RS12335
uniprot id: W0JTQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

797299:HALLA RS11555
gene id: 797299:HALLA_RS11555
uniprot id: W0JNS4
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS04080
gene id: 797299:HALLA_RS04080
uniprot id: W0JNX3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

797299:HALLA RS01570
gene id: 797299:HALLA_RS01570
uniprot id: W0JIU5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

797299:HALLA RS09125
gene id: 797299:HALLA_RS09125
uniprot id: W0JRC9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

797299:HALLA RS00415
gene id: 797299:HALLA_RS00415
uniprot id: W0JMH2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

797299:HALLA RS11740
gene id: 797299:HALLA_RS11740
uniprot id: W0JSP8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS08895
gene id: 797299:HALLA_RS08895
uniprot id: W0JRJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02435
gene id: 797299:HALLA_RS02435
uniprot id: W0JND8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

797299:HALLA RS19580
gene id: 797299:HALLA_RS19580
uniprot id: W0JYR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

797299:HALLA RS07465
gene id: 797299:HALLA_RS07465
uniprot id: W0JQS4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

797299:HALLA RS14205
gene id: 797299:HALLA_RS14205
uniprot id: W0JVD1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS08885
gene id: 797299:HALLA_RS08885
uniprot id: W0JS18
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

797299:HALLA RS00225
gene id: 797299:HALLA_RS00225
uniprot id: W0JM15
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

797299:HALLA RS16310
gene id: 797299:HALLA_RS16310
uniprot id: W0JSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS16540
gene id: 797299:HALLA_RS16540
uniprot id: W0JXH2
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS12675
gene id: 797299:HALLA_RS12675
uniprot id: W0JTV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS16100
gene id: 797299:HALLA_RS16100
uniprot id: W0JSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS09785
gene id: 797299:HALLA_RS09785
uniprot id: W0JMX0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

797299:HALLA RS03695
gene id: 797299:HALLA_RS03695
uniprot id: W0JJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

797299:HALLA RS12460
gene id: 797299:HALLA_RS12460
uniprot id: W0JUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

797299:HALLA RS16425
gene id: 797299:HALLA_RS16425
uniprot id: W0JWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS11710
gene id: 797299:HALLA_RS11710
uniprot id: W0JNL8
names: Similarity
messages: Belongs to the PdaD family.

797299:HALLA RS10000
gene id: 797299:HALLA_RS10000
uniprot id: W0JN10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797299:HALLA RS06160
gene id: 797299:HALLA_RS06160
uniprot id: W0JQ15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797299:HALLA RS19100
gene id: 797299:HALLA_RS19100
uniprot id: W0JZC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS19680
gene id: 797299:HALLA_RS19680
uniprot id: W0JV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797299:HALLA RS01850
gene id: 797299:HALLA_RS01850
uniprot id: W0JNK4
names: Similarity
messages: Belongs to the catalase family.

797299:HALLA RS11370
gene id: 797299:HALLA_RS11370
uniprot id: W0JT75
names: Subcellular Location Annotation
messages: Cytoplasm

797299:HALLA RS03415
gene id: 797299:HALLA_RS03415
uniprot id: W0JNY7
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

797299:HALLA RS11730
gene id: 797299:HALLA_RS11730
uniprot id: W0JSW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS09750
gene id: 797299:HALLA_RS09750
uniprot id: W0JSH8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS07835
gene id: 797299:HALLA_RS07835
uniprot id: W0JQZ1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

797299:HALLA RS12600
gene id: 797299:HALLA_RS12600
uniprot id: W0JPC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

797299:HALLA RS12655
gene id: 797299:HALLA_RS12655
uniprot id: W0JPD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

797299:HALLA RS13075
gene id: 797299:HALLA_RS13075
uniprot id: W0JTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

797299:HALLA RS00005
gene id: 797299:HALLA_RS00005
uniprot id: W0JI68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS09620
gene id: 797299:HALLA_RS09620
uniprot id: W0JRJ7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

797299:HALLA RS00765
gene id: 797299:HALLA_RS00765
uniprot id: W0JMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

797299:HALLA RS14015
gene id: 797299:HALLA_RS14015
uniprot id: W0JUG0
names: Similarity
messages: Belongs to the peptidase S9C family.

797299:HALLA RS02535
gene id: 797299:HALLA_RS02535
uniprot id: W0JNG0
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

797299:HALLA RS11670
gene id: 797299:HALLA_RS11670
uniprot id: W0JSV8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

797299:HALLA RS00300
gene id: 797299:HALLA_RS00300
uniprot id: W0JM27
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

797299:HALLA RS13190
gene id: 797299:HALLA_RS13190
uniprot id: W0JU21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

797299:HALLA RS11515
gene id: 797299:HALLA_RS11515
uniprot id: W0JSJ0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

797299:HALLA RS00465
gene id: 797299:HALLA_RS00465
uniprot id: W0JN11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

797299:HALLA RS08430
gene id: 797299:HALLA_RS08430
uniprot id: W0JM62
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

797299:HALLA RS00280
gene id: 797299:HALLA_RS00280
uniprot id: W0JMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

797299:HALLA RS07090
gene id: 797299:HALLA_RS07090
uniprot id: W0JQK6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03150
gene id: 797299:HALLA_RS03150
uniprot id: W0JNU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS07650
gene id: 797299:HALLA_RS07650
uniprot id: W0JQJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS10405
gene id: 797299:HALLA_RS10405
uniprot id: W0JRX8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

797299:HALLA RS14730
gene id: 797299:HALLA_RS14730
uniprot id: W0JVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS00025
gene id: 797299:HALLA_RS00025
uniprot id: W0JHW2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS18680
gene id: 797299:HALLA_RS18680
uniprot id: W0JY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS05280
gene id: 797299:HALLA_RS05280
uniprot id: W0JPH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

797299:HALLA RS15255
gene id: 797299:HALLA_RS15255
uniprot id: W0JRX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS11520
gene id: 797299:HALLA_RS11520
uniprot id: W0JT98
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

797299:HALLA RS10095
gene id: 797299:HALLA_RS10095
uniprot id: W0JMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

797299:HALLA RS04300
gene id: 797299:HALLA_RS04300
uniprot id: W0JKB8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

797299:HALLA RS09225
gene id: 797299:HALLA_RS09225
uniprot id: W0JS94
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05495
gene id: 797299:HALLA_RS05495
uniprot id: W0JPX6
names: Similarity
messages: Belongs to the UPF0212 family.

797299:HALLA RS18305
gene id: 797299:HALLA_RS18305
uniprot id: W0JU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797299:HALLA RS01825
gene id: 797299:HALLA_RS01825
uniprot id: W0JNK1
names: Similarity
messages: Belongs to the AOR/FOR family.

797299:HALLA RS15155
gene id: 797299:HALLA_RS15155
uniprot id: W0JWK3
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS06420
gene id: 797299:HALLA_RS06420
uniprot id: W0JQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797299:HALLA RS00400
gene id: 797299:HALLA_RS00400
uniprot id: W0JM41
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03090
gene id: 797299:HALLA_RS03090
uniprot id: W0JJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS01460
gene id: 797299:HALLA_RS01460
uniprot id: W0JMH7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

797299:HALLA RS12525
gene id: 797299:HALLA_RS12525
uniprot id: W0JTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797299:HALLA RS16825
gene id: 797299:HALLA_RS16825
uniprot id: W0JX68
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

797299:HALLA RS06030
gene id: 797299:HALLA_RS06030
uniprot id: W0JKT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12515
gene id: 797299:HALLA_RS12515
uniprot id: W0JNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797299:HALLA RS16855
gene id: 797299:HALLA_RS16855
uniprot id: W0JT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS00265
gene id: 797299:HALLA_RS00265
uniprot id: W0JME8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797299:HALLA RS18420
gene id: 797299:HALLA_RS18420
uniprot id: W0JU88
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797299:HALLA RS18250
gene id: 797299:HALLA_RS18250
uniprot id: W0JU52
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797299:HALLA RS12360
gene id: 797299:HALLA_RS12360
uniprot id: W0JV49
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10115
gene id: 797299:HALLA_RS10115
uniprot id: W0JS34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS06080
gene id: 797299:HALLA_RS06080
uniprot id: W0JQA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797299:HALLA RS11130
gene id: 797299:HALLA_RS11130
uniprot id: W0JSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797299:HALLA RS06375
gene id: 797299:HALLA_RS06375
uniprot id: W0JKY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12115
gene id: 797299:HALLA_RS12115
uniprot id: W0JT15
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS19740
gene id: 797299:HALLA_RS19740
uniprot id: W0JV42
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797299:HALLA RS15750
gene id: 797299:HALLA_RS15750
uniprot id: W0JSH7
names: Similarity
messages: Belongs to the Dps family.

797299:HALLA RS00030
gene id: 797299:HALLA_RS00030
uniprot id: W0JLY6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797299:HALLA RS14615
gene id: 797299:HALLA_RS14615
uniprot id: W0JRV6
names: Similarity
messages: Belongs to the BtpA family.

797299:HALLA RS08555
gene id: 797299:HALLA_RS08555
uniprot id: W0JLV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

797299:HALLA RS05145
gene id: 797299:HALLA_RS05145
uniprot id: W0JKA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS10720
gene id: 797299:HALLA_RS10720
uniprot id: W0JSW9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

797299:HALLA RS10120
gene id: 797299:HALLA_RS10120
uniprot id: W0JMR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

797299:HALLA RS09575
gene id: 797299:HALLA_RS09575
uniprot id: W0JSE9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS17155
gene id: 797299:HALLA_RS17155
uniprot id: W0JX65
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS04105
gene id: 797299:HALLA_RS04105
uniprot id: W0JJT8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797299:HALLA RS14465
gene id: 797299:HALLA_RS14465
uniprot id: W0JW57
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

797299:HALLA RS03360
gene id: 797299:HALLA_RS03360
uniprot id: W0JNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

797299:HALLA RS19375
gene id: 797299:HALLA_RS19375
uniprot id: W0JYM5
names: Similarity
messages: Belongs to the manganese catalase family.

797299:HALLA RS07550
gene id: 797299:HALLA_RS07550
uniprot id: W0JQI2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

797299:HALLA RS14875
gene id: 797299:HALLA_RS14875
uniprot id: W0JVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS14485
gene id: 797299:HALLA_RS14485
uniprot id: W0JVE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS13250
gene id: 797299:HALLA_RS13250
uniprot id: W0JTA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS00335
gene id: 797299:HALLA_RS00335
uniprot id: W0JMF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

797299:HALLA RS13425
gene id: 797299:HALLA_RS13425
uniprot id: W0JTK1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797299:HALLA RS12530
gene id: 797299:HALLA_RS12530
uniprot id: W0JPB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797299:HALLA RS00070
gene id: 797299:HALLA_RS00070
uniprot id: W0JI78
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS03490
gene id: 797299:HALLA_RS03490
uniprot id: W0JP01
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797299:HALLA RS18530
gene id: 797299:HALLA_RS18530
uniprot id: W0JUA2
names: Similarity
messages: Belongs to the pirin family.

797299:HALLA RS08630
gene id: 797299:HALLA_RS08630
uniprot id: W0JRV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

797299:HALLA RS06300
gene id: 797299:HALLA_RS06300
uniprot id: W0JQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797299:HALLA RS00490
gene id: 797299:HALLA_RS00490
uniprot id: W0JN15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

797299:HALLA RS00190
gene id: 797299:HALLA_RS00190
uniprot id: W0JMD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS15090
gene id: 797299:HALLA_RS15090
uniprot id: W0JS39
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

797299:HALLA RS05150
gene id: 797299:HALLA_RS05150
uniprot id: W0JPF0
names: Similarity
messages: Belongs to the glutaredoxin family.

797299:HALLA RS18445
gene id: 797299:HALLA_RS18445
uniprot id: W0JYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS13545
gene id: 797299:HALLA_RS13545
uniprot id: W0JPS3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

797299:HALLA RS09835
gene id: 797299:HALLA_RS09835
uniprot id: W0JSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

797299:HALLA RS15400
gene id: 797299:HALLA_RS15400
uniprot id: W0JW49
names: Similarity
messages: Belongs to the SCO1/2 family.

797299:HALLA RS03075
gene id: 797299:HALLA_RS03075
uniprot id: W0JNF7
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

797299:HALLA RS00510
gene id: 797299:HALLA_RS00510
uniprot id: W0JM55
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

797299:HALLA RS03055
gene id: 797299:HALLA_RS03055
uniprot id: W0JPA6
names: Function
messages: Part of a potassium transport system.

797299:HALLA RS18375
gene id: 797299:HALLA_RS18375
uniprot id: W0JU77
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

797299:HALLA RS05365
gene id: 797299:HALLA_RS05365
uniprot id: W0JKT0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797299:HALLA RS12230
gene id: 797299:HALLA_RS12230
uniprot id: W0JP64
names: Similarity
messages: Belongs to the PDCD5 family.

797299:HALLA RS14915
gene id: 797299:HALLA_RS14915
uniprot id: W0JVN1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS09880
gene id: 797299:HALLA_RS09880
uniprot id: W0JRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.

797299:HALLA RS01930
gene id: 797299:HALLA_RS01930
uniprot id: W0JJ16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS00130
gene id: 797299:HALLA_RS00130
uniprot id: W0JMV3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797299:HALLA RS19555
gene id: 797299:HALLA_RS19555
uniprot id: W0JYR2
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS15250
gene id: 797299:HALLA_RS15250
uniprot id: W0JW29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797299:HALLA RS02515
gene id: 797299:HALLA_RS02515
uniprot id: W0JIZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

797299:HALLA RS02865
gene id: 797299:HALLA_RS02865
uniprot id: W0JNQ2
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

797299:HALLA RS09635
gene id: 797299:HALLA_RS09635
uniprot id: W0JRV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

797299:HALLA RS08890
gene id: 797299:HALLA_RS08890
uniprot id: W0JMF9
names: Function
messages: Part of a potassium transport system.

797299:HALLA RS06510
gene id: 797299:HALLA_RS06510
uniprot id: W0JL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

797299:HALLA RS00420
gene id: 797299:HALLA_RS00420
uniprot id: W0JI19
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

797299:HALLA RS13420
gene id: 797299:HALLA_RS13420
uniprot id: W0JPQ0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS00740
gene id: 797299:HALLA_RS00740
uniprot id: W0JMM7
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

797299:HALLA RS00545
gene id: 797299:HALLA_RS00545
uniprot id: W0JIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

797299:HALLA RS12200
gene id: 797299:HALLA_RS12200
uniprot id: W0JP60
names: Similarity
messages: Belongs to the proline racemase family.

797299:HALLA RS16545
gene id: 797299:HALLA_RS16545
uniprot id: W0JWY1
names: Similarity
messages: Belongs to the AHA1 family.

797299:HALLA RS18850
gene id: 797299:HALLA_RS18850
uniprot id: W0JZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

797299:HALLA RS16230
gene id: 797299:HALLA_RS16230
uniprot id: W0JWH4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797299:HALLA RS03925
gene id: 797299:HALLA_RS03925
uniprot id: W0JP73
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

797299:HALLA RS01790
gene id: 797299:HALLA_RS01790
uniprot id: W0JN23
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS12100
gene id: 797299:HALLA_RS12100
uniprot id: W0JSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

797299:HALLA RS02480
gene id: 797299:HALLA_RS02480
uniprot id: W0JJA6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS16295
gene id: 797299:HALLA_RS16295
uniprot id: W0JSM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS11445
gene id: 797299:HALLA_RS11445
uniprot id: W0JSP9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS10955
gene id: 797299:HALLA_RS10955
uniprot id: W0JN58
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

797299:HALLA RS17285
gene id: 797299:HALLA_RS17285
uniprot id: W0JTF4
names: Similarity
messages: Belongs to the RutC family.

797299:HALLA RS15505
gene id: 797299:HALLA_RS15505
uniprot id: W0JS25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

797299:HALLA RS02010
gene id: 797299:HALLA_RS02010
uniprot id: W0JN70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

797299:HALLA RS18790
gene id: 797299:HALLA_RS18790
uniprot id: W0JUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS14980
gene id: 797299:HALLA_RS14980
uniprot id: W0JVY1
names: Subcellular Location Annotation
messages: Cell membrane

797299:HALLA RS03070
gene id: 797299:HALLA_RS03070
uniprot id: W0JJB4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797299:HALLA RS02280
gene id: 797299:HALLA_RS02280
uniprot id: W0JJ72
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

797299:HALLA RS02885
gene id: 797299:HALLA_RS02885
uniprot id: W0JJL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

797299:HALLA RS02145
gene id: 797299:HALLA_RS02145
uniprot id: W0JN93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

797299:HALLA RS13995
gene id: 797299:HALLA_RS13995
uniprot id: W0JPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797299:HALLA RS08390
gene id: 797299:HALLA_RS08390
uniprot id: W0JLS0
names: Similarity
messages: Belongs to the Nth/MutY family.

797299:HALLA RS00275
gene id: 797299:HALLA_RS00275
uniprot id: W0JM23
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

797299:HALLA RS09675
gene id: 797299:HALLA_RS09675
uniprot id: W0JSG7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797299:HALLA RS12235
gene id: 797299:HALLA_RS12235
uniprot id: W0JT30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

797299:HALLA RS12245
gene id: 797299:HALLA_RS12245
uniprot id: W0JSV9
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS05030
gene id: 797299:HALLA_RS05030
uniprot id: W0JQ68
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

797299:HALLA RS15370
gene id: 797299:HALLA_RS15370
uniprot id: W0JS93
names: Similarity
messages: Belongs to the glutamine synthetase family.

797299:HALLA RS03605
gene id: 797299:HALLA_RS03605
uniprot id: W0JJY0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797299:HALLA RS12805
gene id: 797299:HALLA_RS12805
uniprot id: W0JPF7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

797299:HALLA RS15980
gene id: 797299:HALLA_RS15980
uniprot id: W0JWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS08960
gene id: 797299:HALLA_RS08960
uniprot id: W0JM68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797299:HALLA RS16055
gene id: 797299:HALLA_RS16055
uniprot id: W0JSP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

797299:HALLA RS11645
gene id: 797299:HALLA_RS11645
uniprot id: W0JSV5
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02285
gene id: 797299:HALLA_RS02285
uniprot id: W0JNB5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797299:HALLA RS00535
gene id: 797299:HALLA_RS00535
uniprot id: W0JM59
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

797299:HALLA RS13630
gene id: 797299:HALLA_RS13630
uniprot id: W0JPT6
names: Similarity
messages: Belongs to the aspartokinase family.

797299:HALLA RS17415
gene id: 797299:HALLA_RS17415
uniprot id: W0JXJ0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797299:HALLA RS19630
gene id: 797299:HALLA_RS19630
uniprot id: W0JYZ0
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS02660
gene id: 797299:HALLA_RS02660
uniprot id: W0JN49
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

797299:HALLA RS00865
gene id: 797299:HALLA_RS00865
uniprot id: W0JMP6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

797299:HALLA RS08120
gene id: 797299:HALLA_RS08120
uniprot id: W0JRK6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS15065
gene id: 797299:HALLA_RS15065
uniprot id: W0JS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS05345
gene id: 797299:HALLA_RS05345
uniprot id: W0JPU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797299:HALLA RS10105
gene id: 797299:HALLA_RS10105
uniprot id: W0JSM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

797299:HALLA RS11400
gene id: 797299:HALLA_RS11400
uniprot id: W0JT79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

797299:HALLA RS11715
gene id: 797299:HALLA_RS11715
uniprot id: W0JSP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797299:HALLA RS14345
gene id: 797299:HALLA_RS14345
uniprot id: W0JW16
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS08650
gene id: 797299:HALLA_RS08650
uniprot id: W0JR24
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

797299:HALLA RS13325
gene id: 797299:HALLA_RS13325
uniprot id: W0JTI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

797299:HALLA RS10485
gene id: 797299:HALLA_RS10485
uniprot id: W0JST6
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS09700
gene id: 797299:HALLA_RS09700
uniprot id: W0JSH2
names: Function
messages: Part of a potassium transport system.

797299:HALLA RS01520
gene id: 797299:HALLA_RS01520
uniprot id: W0JMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

797299:HALLA RS10170
gene id: 797299:HALLA_RS10170
uniprot id: W0JMS2
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

797299:HALLA RS04740
gene id: 797299:HALLA_RS04740
uniprot id: W0JKG9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797299:HALLA RS15725
gene id: 797299:HALLA_RS15725
uniprot id: W0JW45
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

797299:HALLA RS13855
gene id: 797299:HALLA_RS13855
uniprot id: W0JTT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

797299:HALLA RS05840
gene id: 797299:HALLA_RS05840
uniprot id: W0JQ70
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797299:HALLA RS01565
gene id: 797299:HALLA_RS01565
uniprot id: W0JNF9
names: Similarity
messages: Belongs to the MoaB/Mog family.

797299:HALLA RS18450
gene id: 797299:HALLA_RS18450
uniprot id: W0JY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS04015
gene id: 797299:HALLA_RS04015
uniprot id: W0JK63
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS09395
gene id: 797299:HALLA_RS09395
uniprot id: W0JMQ5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797299:HALLA RS03985
gene id: 797299:HALLA_RS03985
uniprot id: W0JPS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

797299:HALLA RS14005
gene id: 797299:HALLA_RS14005
uniprot id: W0JPN1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

797299:HALLA RS08410
gene id: 797299:HALLA_RS08410
uniprot id: W0JR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

797299:HALLA RS15985
gene id: 797299:HALLA_RS15985
uniprot id: W0JX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797299:HALLA RS04065
gene id: 797299:HALLA_RS04065
uniprot id: W0JK75
names: Similarity
messages: Belongs to the complex I subunit 3 family.

797299:HALLA RS17380
gene id: 797299:HALLA_RS17380
uniprot id: W0JXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797299:HALLA RS11230
gene id: 797299:HALLA_RS11230
uniprot id: W0JSL1
names: Subcellular Location Annotation
messages: Membrane

797299:HALLA RS11295
gene id: 797299:HALLA_RS11295
uniprot id: W0JT61
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

797299:HALLA RS05665
gene id: 797299:HALLA_RS05665
uniprot id: W0JPQ8
names: Similarity
messages: Belongs to the UPF0047 family.

797299:HALLA RS14145
gene id: 797299:HALLA_RS14145
uniprot id: W0JVX5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797299:HALLA RS07610
gene id: 797299:HALLA_RS07610
uniprot id: W0JQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane