79604:AAY81 RS02300
gene id: 79604:AAY81_RS02300
uniprot id: A0A172RWS0
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

79604:AAY81 RS02490
gene id: 79604:AAY81_RS02490
uniprot id: A0A172RWV1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04475
gene id: 79604:AAY81_RS04475
uniprot id: A0A172RXS8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

79604:AAY81 RS07455
gene id: 79604:AAY81_RS07455
uniprot id: A0A172RZ76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS03295
gene id: 79604:AAY81_RS03295
uniprot id: A0A172RXD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

79604:AAY81 RS04120
gene id: 79604:AAY81_RS04120
uniprot id: A0A172RXJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

79604:AAY81 RS07340
gene id: 79604:AAY81_RS07340
uniprot id: A0A172RZC4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

79604:AAY81 RS01850
gene id: 79604:AAY81_RS01850
uniprot id: A0A172RWS6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

79604:AAY81 RS00010
gene id: 79604:AAY81_RS00010
uniprot id: A0A172RVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

79604:AAY81 RS07395
gene id: 79604:AAY81_RS07395
uniprot id: A0A172RZ07
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

79604:AAY81 RS06255
gene id: 79604:AAY81_RS06255
uniprot id: A0A172RYM8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

79604:AAY81 RS05310
gene id: 79604:AAY81_RS05310
uniprot id: A0A172RY46
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

79604:AAY81 RS02515
gene id: 79604:AAY81_RS02515
uniprot id: A0A172RX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

79604:AAY81 RS02150
gene id: 79604:AAY81_RS02150
uniprot id: A0A172RWP4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

79604:AAY81 RS08850
gene id: 79604:AAY81_RS08850
uniprot id: A0A172RZN6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05765
gene id: 79604:AAY81_RS05765
uniprot id: A0A172RYA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

79604:AAY81 RS09255
gene id: 79604:AAY81_RS09255
uniprot id: A0A172RZV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

79604:AAY81 RS02345
gene id: 79604:AAY81_RS02345
uniprot id: A0A172RWT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS06050
gene id: 79604:AAY81_RS06050
uniprot id: A0A172RYG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

79604:AAY81 RS04725
gene id: 79604:AAY81_RS04725
uniprot id: A0A172RXY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

79604:AAY81 RS09320
gene id: 79604:AAY81_RS09320
uniprot id: A0A1H8P9E2
names: Similarity
messages: Belongs to the cytochrome c-552 family.

79604:AAY81 RS09130
gene id: 79604:AAY81_RS09130
uniprot id: A0A172RZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

79604:AAY81 RS05615
gene id: 79604:AAY81_RS05615
uniprot id: A0A172RYB9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

79604:AAY81 RS03195
gene id: 79604:AAY81_RS03195
uniprot id: A0A172RX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

79604:AAY81 RS05455
gene id: 79604:AAY81_RS05455
uniprot id: A0A172RY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

79604:AAY81 RS08150
gene id: 79604:AAY81_RS08150
uniprot id: A0A172RZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

79604:AAY81 RS07425
gene id: 79604:AAY81_RS07425
uniprot id: A0A172RZ19
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01835
gene id: 79604:AAY81_RS01835
uniprot id: A0A172RWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

79604:AAY81 RS05795
gene id: 79604:AAY81_RS05795
uniprot id: A0A172RYF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

79604:AAY81 RS05980
gene id: 79604:AAY81_RS05980
uniprot id: A0A172RYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

79604:AAY81 RS02440
gene id: 79604:AAY81_RS02440
uniprot id: A0A172S0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

79604:AAY81 RS08175
gene id: 79604:AAY81_RS08175
uniprot id: A0A172RZC7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

79604:AAY81 RS05835
gene id: 79604:AAY81_RS05835
uniprot id: A0A172RYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

79604:AAY81 RS01135
gene id: 79604:AAY81_RS01135
uniprot id: A0A172RWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

79604:AAY81 RS05425
gene id: 79604:AAY81_RS05425
uniprot id: A0A172RY41
names: Similarity
messages: Belongs to the UPF0102 family.

79604:AAY81 RS07635
gene id: 79604:AAY81_RS07635
uniprot id: A0A172RZ44
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS00600
gene id: 79604:AAY81_RS00600
uniprot id: A0A172RW20
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

79604:AAY81 RS01500
gene id: 79604:AAY81_RS01500
uniprot id: A0A172RWE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS01790
gene id: 79604:AAY81_RS01790
uniprot id: A0A1H8TEV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

79604:AAY81 RS01735
gene id: 79604:AAY81_RS01735
uniprot id: A0A172RWI7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

79604:AAY81 RS08970
gene id: 79604:AAY81_RS08970
uniprot id: A0A172RZT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

79604:AAY81 RS01200
gene id: 79604:AAY81_RS01200
uniprot id: A0A172RWH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS08045
gene id: 79604:AAY81_RS08045
uniprot id: A0A172RZA6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01595
gene id: 79604:AAY81_RS01595
uniprot id: A0A172RWI2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

79604:AAY81 RS00660
gene id: 79604:AAY81_RS00660
uniprot id: A0A172RWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

79604:AAY81 RS01665
gene id: 79604:AAY81_RS01665
uniprot id: A0A172RWH9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

79604:AAY81 RS09250
gene id: 79604:AAY81_RS09250
uniprot id: A0A1H8P8F6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01940
gene id: 79604:AAY81_RS01940
uniprot id: A0A172S0H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

79604:AAY81 RS08455
gene id: 79604:AAY81_RS08455
uniprot id: A0A172RZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

79604:AAY81 RS00160
gene id: 79604:AAY81_RS00160
uniprot id: A0A172RVT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

79604:AAY81 RS05910
gene id: 79604:AAY81_RS05910
uniprot id: A0A172RYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

79604:AAY81 RS00025
gene id: 79604:AAY81_RS00025
uniprot id: A0A172RVS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

79604:AAY81 RS05420
gene id: 79604:AAY81_RS05420
uniprot id: A0A172RY75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

79604:AAY81 RS00415
gene id: 79604:AAY81_RS00415
uniprot id: A0A172RVX9
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

79604:AAY81 RS09065
gene id: 79604:AAY81_RS09065
uniprot id: A0A172RZS7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

79604:AAY81 RS05975
gene id: 79604:AAY81_RS05975
uniprot id: A0A172RYD1
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

79604:AAY81 RS08610
gene id: 79604:AAY81_RS08610
uniprot id: A0A172RZX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

79604:AAY81 RS00200
gene id: 79604:AAY81_RS00200
uniprot id: A0A172RVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

79604:AAY81 RS01650
gene id: 79604:AAY81_RS01650
uniprot id: A0A172RWT5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

79604:AAY81 RS05120
gene id: 79604:AAY81_RS05120
uniprot id: A0A172RY04
names: Similarity
messages: Belongs to the PspA/IM30 family.

79604:AAY81 RS07210
gene id: 79604:AAY81_RS07210
uniprot id: A0A172RYZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

79604:AAY81 RS06950
gene id: 79604:AAY81_RS06950
uniprot id: A0A172RYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

79604:AAY81 RS07460
gene id: 79604:AAY81_RS07460
uniprot id: A0A172RZE5
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

79604:AAY81 RS04340
gene id: 79604:AAY81_RS04340
uniprot id: A0A1H8SNC8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

79604:AAY81 RS10060
gene id: 79604:AAY81_RS10060
uniprot id: A0A1H8U593
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

79604:AAY81 RS02445
gene id: 79604:AAY81_RS02445
uniprot id: A0A172RX55
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

79604:AAY81 RS05105
gene id: 79604:AAY81_RS05105
uniprot id: A0A172RXZ7
names: Similarity
messages: Belongs to the peptidase A31 family.

79604:AAY81 RS05645
gene id: 79604:AAY81_RS05645
uniprot id: A0A172RYA2
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

79604:AAY81 RS02730
gene id: 79604:AAY81_RS02730
uniprot id: A0A172RWZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS02945
gene id: 79604:AAY81_RS02945
uniprot id: A0A172RX17
names: Similarity
messages: Belongs to the ABC transporter superfamily.

79604:AAY81 RS08070
gene id: 79604:AAY81_RS08070
uniprot id: A0A172RZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

79604:AAY81 RS08280
gene id: 79604:AAY81_RS08280
uniprot id: A0A172RZM5
names: Similarity
messages: Belongs to the peptidase C40 family.

79604:AAY81 RS09190
gene id: 79604:AAY81_RS09190
uniprot id: A0A172RZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

79604:AAY81 RS07130
gene id: 79604:AAY81_RS07130
uniprot id: A0A172RYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

79604:AAY81 RS05700
gene id: 79604:AAY81_RS05700
uniprot id: A0A172RY81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

79604:AAY81 RS03700
gene id: 79604:AAY81_RS03700
uniprot id: A0A172RXD6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

79604:AAY81 RS06375
gene id: 79604:AAY81_RS06375
uniprot id: A0A172RYK3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

79604:AAY81 RS07290
gene id: 79604:AAY81_RS07290
uniprot id: A0A172RZB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

79604:AAY81 RS05255
gene id: 79604:AAY81_RS05255
uniprot id: A0A172RY60
names: Similarity
messages: Belongs to the carbamate kinase family.

79604:AAY81 RS07275
gene id: 79604:AAY81_RS07275
uniprot id: A0A172RYZ3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06540
gene id: 79604:AAY81_RS06540
uniprot id: A0A172RYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

79604:AAY81 RS08255
gene id: 79604:AAY81_RS08255
uniprot id: A0A172RZR6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

79604:AAY81 RS07360
gene id: 79604:AAY81_RS07360
uniprot id: A0A172RZ08
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05565
gene id: 79604:AAY81_RS05565
uniprot id: A0A172RY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

79604:AAY81 RS07720
gene id: 79604:AAY81_RS07720
uniprot id: A0A172RZC0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

79604:AAY81 RS03605
gene id: 79604:AAY81_RS03605
uniprot id: A0A172RX98
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

79604:AAY81 RS08540
gene id: 79604:AAY81_RS08540
uniprot id: A0A172RZW7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

79604:AAY81 RS01475
gene id: 79604:AAY81_RS01475
uniprot id: A0A172RWL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

79604:AAY81 RS07530
gene id: 79604:AAY81_RS07530
uniprot id: A0A172RZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

79604:AAY81 RS01280
gene id: 79604:AAY81_RS01280
uniprot id: A0A172RWB7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

79604:AAY81 RS03730
gene id: 79604:AAY81_RS03730
uniprot id: A0A172RXE4
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS00420
gene id: 79604:AAY81_RS00420
uniprot id: A0A172RW05
names: Similarity
messages: Belongs to the HupF/HypC family.

79604:AAY81 RS04115
gene id: 79604:AAY81_RS04115
uniprot id: A0A172RXR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

79604:AAY81 RS00655
gene id: 79604:AAY81_RS00655
uniprot id: A0A172RWC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS04255
gene id: 79604:AAY81_RS04255
uniprot id: A0A172RXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

79604:AAY81 RS08820
gene id: 79604:AAY81_RS08820
uniprot id: A0A172RZU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

79604:AAY81 RS07960
gene id: 79604:AAY81_RS07960
uniprot id: A0A172RZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS02850
gene id: 79604:AAY81_RS02850
uniprot id: A0A172RWX8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

79604:AAY81 RS07525
gene id: 79604:AAY81_RS07525
uniprot id: A0A172RZF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

79604:AAY81 RS05815
gene id: 79604:AAY81_RS05815
uniprot id: A0A172RYC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

79604:AAY81 RS01805
gene id: 79604:AAY81_RS01805
uniprot id: A0A172RWJ4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

79604:AAY81 RS00520
gene id: 79604:AAY81_RS00520
uniprot id: A0A172RW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

79604:AAY81 RS02530
gene id: 79604:AAY81_RS02530
uniprot id: A0A172RWV5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

79604:AAY81 RS01230
gene id: 79604:AAY81_RS01230
uniprot id: A0A172RWA5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

79604:AAY81 RS00145
gene id: 79604:AAY81_RS00145
uniprot id: A0A172RVU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

79604:AAY81 RS06140
gene id: 79604:AAY81_RS06140
uniprot id: A0A172RYL5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

79604:AAY81 RS07115
gene id: 79604:AAY81_RS07115
uniprot id: A0A172RZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

79604:AAY81 RS01930
gene id: 79604:AAY81_RS01930
uniprot id: A0A172RWL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

79604:AAY81 RS09910
gene id: 79604:AAY81_RS09910
uniprot id: A0A172S037
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

79604:AAY81 RS05715
gene id: 79604:AAY81_RS05715
uniprot id: A0A172RY99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

79604:AAY81 RS09195
gene id: 79604:AAY81_RS09195
uniprot id: A0A172RZU8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

79604:AAY81 RS02140
gene id: 79604:AAY81_RS02140
uniprot id: A0A172RWP5
names: Similarity
messages: Belongs to the universal stress protein A family.

79604:AAY81 RS05950
gene id: 79604:AAY81_RS05950
uniprot id: A0A172RYP3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

79604:AAY81 RS06425
gene id: 79604:AAY81_RS06425
uniprot id: A0A172RYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

79604:AAY81 RS08545
gene id: 79604:AAY81_RS08545
uniprot id: A0A172RZP3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

79604:AAY81 RS01530
gene id: 79604:AAY81_RS01530
uniprot id: A0A172RWM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

79604:AAY81 RS02100
gene id: 79604:AAY81_RS02100
uniprot id: A0A172RWL7
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01780
gene id: 79604:AAY81_RS01780
uniprot id: A0A172RWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

79604:AAY81 RS01660
gene id: 79604:AAY81_RS01660
uniprot id: A0A172RWP8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

79604:AAY81 RS01195
gene id: 79604:AAY81_RS01195
uniprot id: A0A172RWI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS05430
gene id: 79604:AAY81_RS05430
uniprot id: A0A172RY66
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

79604:AAY81 RS06265
gene id: 79604:AAY81_RS06265
uniprot id: A0A172RYN6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS02005
gene id: 79604:AAY81_RS02005
uniprot id: A0A172RWN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

79604:AAY81 RS03850
gene id: 79604:AAY81_RS03850
uniprot id: A0A172RXG9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

79604:AAY81 RS01655
gene id: 79604:AAY81_RS01655
uniprot id: A0A172RWQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

79604:AAY81 RS05200
gene id: 79604:AAY81_RS05200
uniprot id: A0A1H8TLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

79604:AAY81 RS00735
gene id: 79604:AAY81_RS00735
uniprot id: A0A172RW46
names: Similarity
messages: Belongs to the peptidase M18 family.

79604:AAY81 RS08095
gene id: 79604:AAY81_RS08095
uniprot id: A0A172RZC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

79604:AAY81 RS08585
gene id: 79604:AAY81_RS08585
uniprot id: A0A172RZJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS00005
gene id: 79604:AAY81_RS00005
uniprot id: A0A172RVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

79604:AAY81 RS09410
gene id: 79604:AAY81_RS09410
uniprot id: A0A172S035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

79604:AAY81 RS07825
gene id: 79604:AAY81_RS07825
uniprot id: A0A172RZF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS09090
gene id: 79604:AAY81_RS09090
uniprot id: A0A172RZY1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

79604:AAY81 RS01820
gene id: 79604:AAY81_RS01820
uniprot id: A0A172RWK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

79604:AAY81 RS04790
gene id: 79604:AAY81_RS04790
uniprot id: A0A172RXX0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

79604:AAY81 RS09050
gene id: 79604:AAY81_RS09050
uniprot id: A0A1H8P4B4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

79604:AAY81 RS06555
gene id: 79604:AAY81_RS06555
uniprot id: A0A172RYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

79604:AAY81 RS05385
gene id: 79604:AAY81_RS05385
uniprot id: A0A172RY49
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

79604:AAY81 RS00585
gene id: 79604:AAY81_RS00585
uniprot id: A0A172RWB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

79604:AAY81 RS02285
gene id: 79604:AAY81_RS02285
uniprot id: A0A172RWS5
names: Similarity
messages: Belongs to the RecJ family.

79604:AAY81 RS08635
gene id: 79604:AAY81_RS08635
uniprot id: A0A172RZM6
names: Similarity
messages: Belongs to the glutamine synthetase family.

79604:AAY81 RS03400
gene id: 79604:AAY81_RS03400
uniprot id: A0A1H8R2A3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05165
gene id: 79604:AAY81_RS05165
uniprot id: A0A172RY28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS09500
gene id: 79604:AAY81_RS09500
uniprot id: A0A172S011
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

79604:AAY81 RS04160
gene id: 79604:AAY81_RS04160
uniprot id: A0A172RXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

79604:AAY81 RS05880
gene id: 79604:AAY81_RS05880
uniprot id: A0A172RYD7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

79604:AAY81 RS08655
gene id: 79604:AAY81_RS08655
uniprot id: A0A172RZL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS07200
gene id: 79604:AAY81_RS07200
uniprot id: A0A172RYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

79604:AAY81 RS07640
gene id: 79604:AAY81_RS07640
uniprot id: A0A1H8S9A5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

79604:AAY81 RS04575
gene id: 79604:AAY81_RS04575
uniprot id: A0A172RXR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

79604:AAY81 RS04235
gene id: 79604:AAY81_RS04235
uniprot id: A0A172RXL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

79604:AAY81 RS06575
gene id: 79604:AAY81_RS06575
uniprot id: A0A172RZ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

79604:AAY81 RS00570
gene id: 79604:AAY81_RS00570
uniprot id: A0A172S0E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS07195
gene id: 79604:AAY81_RS07195
uniprot id: A0A172RYZ7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

79604:AAY81 RS09925
gene id: 79604:AAY81_RS09925
uniprot id: A0A172S0B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

79604:AAY81 RS01095
gene id: 79604:AAY81_RS01095
uniprot id: A0A1H8U608
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

79604:AAY81 RS04625
gene id: 79604:AAY81_RS04625
uniprot id: A0A172RXT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS05665
gene id: 79604:AAY81_RS05665
uniprot id: A0A172RY89
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

79604:AAY81 RS04155
gene id: 79604:AAY81_RS04155
uniprot id: A0A172RXV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

79604:AAY81 RS01755
gene id: 79604:AAY81_RS01755
uniprot id: A0A172RWI9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

79604:AAY81 RS07540
gene id: 79604:AAY81_RS07540
uniprot id: A0A172RZ55
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

79604:AAY81 RS06600
gene id: 79604:AAY81_RS06600
uniprot id: A0A172RYQ4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

79604:AAY81 RS07000
gene id: 79604:AAY81_RS07000
uniprot id: A0A172RYW9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS05725
gene id: 79604:AAY81_RS05725
uniprot id: A0A172RYD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

79604:AAY81 RS05475
gene id: 79604:AAY81_RS05475
uniprot id: A0A172RYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

79604:AAY81 RS04345
gene id: 79604:AAY81_RS04345
uniprot id: A0A172RXY8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

79604:AAY81 RS02255
gene id: 79604:AAY81_RS02255
uniprot id: A0A172RWR0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

79604:AAY81 RS01860
gene id: 79604:AAY81_RS01860
uniprot id: A0A172RWL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS05770
gene id: 79604:AAY81_RS05770
uniprot id: A0A172RYA4
names: Similarity
messages: Belongs to the UPF0234 family.

79604:AAY81 RS03690
gene id: 79604:AAY81_RS03690
uniprot id: A0A172RXJ6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

79604:AAY81 RS04615
gene id: 79604:AAY81_RS04615
uniprot id: A0A172RXS2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

79604:AAY81 RS04955
gene id: 79604:AAY81_RS04955
uniprot id: A0A1H8UJZ3
names: Similarity
messages: Belongs to the peptidase S14 family.

79604:AAY81 RS00255
gene id: 79604:AAY81_RS00255
uniprot id: A0A172RVW6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01540
gene id: 79604:AAY81_RS01540
uniprot id: A0A172RWH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

79604:AAY81 RS08650
gene id: 79604:AAY81_RS08650
uniprot id: A0A172RZM3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

79604:AAY81 RS00525
gene id: 79604:AAY81_RS00525
uniprot id: A0A172RW10
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

79604:AAY81 RS09060
gene id: 79604:AAY81_RS09060
uniprot id: A0A172RZR4
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS03650
gene id: 79604:AAY81_RS03650
uniprot id: A0A172RXD3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS03185
gene id: 79604:AAY81_RS03185
uniprot id: A0A172RX54
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

79604:AAY81 RS04240
gene id: 79604:AAY81_RS04240
uniprot id: A0A172RXM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

79604:AAY81 RS06935
gene id: 79604:AAY81_RS06935
uniprot id: A0A172RYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

79604:AAY81 RS07045
gene id: 79604:AAY81_RS07045
uniprot id: A0A172RZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

79604:AAY81 RS08160
gene id: 79604:AAY81_RS08160
uniprot id: A0A172RZD1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

79604:AAY81 RS01830
gene id: 79604:AAY81_RS01830
uniprot id: A0A172RWI1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

79604:AAY81 RS08740
gene id: 79604:AAY81_RS08740
uniprot id: A0A172RZL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

79604:AAY81 RS09905
gene id: 79604:AAY81_RS09905
uniprot id: A0A172S039
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

79604:AAY81 RS09230
gene id: 79604:AAY81_RS09230
uniprot id: A0A172RZZ5
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

79604:AAY81 RS04420
gene id: 79604:AAY81_RS04420
uniprot id: A0A172RXU0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

79604:AAY81 RS09515
gene id: 79604:AAY81_RS09515
uniprot id: A0A172S014
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

79604:AAY81 RS04740
gene id: 79604:AAY81_RS04740
uniprot id: A0A172RXT8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

79604:AAY81 RS07845
gene id: 79604:AAY81_RS07845
uniprot id: A0A172RZ88
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

79604:AAY81 RS06415
gene id: 79604:AAY81_RS06415
uniprot id: A0A172RYM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

79604:AAY81 RS01700
gene id: 79604:AAY81_RS01700
uniprot id: A0A172RWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

79604:AAY81 RS06165
gene id: 79604:AAY81_RS06165
uniprot id: A0A172RYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

79604:AAY81 RS01865
gene id: 79604:AAY81_RS01865
uniprot id: A0A172RWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

79604:AAY81 RS00500
gene id: 79604:AAY81_RS00500
uniprot id: A0A172RW14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

79604:AAY81 RS04720
gene id: 79604:AAY81_RS04720
uniprot id: A0A172RY44
names: Similarity
messages: Belongs to the NadC/ModD family.

79604:AAY81 RS06670
gene id: 79604:AAY81_RS06670
uniprot id: A0A172RYR8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

79604:AAY81 RS07100
gene id: 79604:AAY81_RS07100
uniprot id: A0A172RZ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

79604:AAY81 RS04470
gene id: 79604:AAY81_RS04470
uniprot id: A0A172RXP8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

79604:AAY81 RS06500
gene id: 79604:AAY81_RS06500
uniprot id: A0A172RYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

79604:AAY81 RS04580
gene id: 79604:AAY81_RS04580
uniprot id: A0A172S0E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

79604:AAY81 RS00110
gene id: 79604:AAY81_RS00110
uniprot id: A0A172RVT2
names: Similarity
messages: Belongs to the HypE family.

79604:AAY81 RS06900
gene id: 79604:AAY81_RS06900
uniprot id: A0A172RZ49
names: Similarity
messages: Belongs to the YggT family.

79604:AAY81 RS07405
gene id: 79604:AAY81_RS07405
uniprot id: A0A172RZD5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

79604:AAY81 RS08085
gene id: 79604:AAY81_RS08085
uniprot id: A0A172RZD4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

79604:AAY81 RS04550
gene id: 79604:AAY81_RS04550
uniprot id: A0A172RXY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

79604:AAY81 RS09855
gene id: 79604:AAY81_RS09855
uniprot id: A0A172S0A6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS00620
gene id: 79604:AAY81_RS00620
uniprot id: A0A1H8PV52
names: Similarity
messages: Belongs to the LOG family.

79604:AAY81 RS09100
gene id: 79604:AAY81_RS09100
uniprot id: A0A172RZX2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

79604:AAY81 RS01825
gene id: 79604:AAY81_RS01825
uniprot id: A0A172RWK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

79604:AAY81 RS04195
gene id: 79604:AAY81_RS04195
uniprot id: A0A172RXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

79604:AAY81 RS06630
gene id: 79604:AAY81_RS06630
uniprot id: A0A172RYT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04175
gene id: 79604:AAY81_RS04175
uniprot id: A0A172RXL0
names: Similarity
messages: Belongs to the asp23 family.

79604:AAY81 RS05380
gene id: 79604:AAY81_RS05380
uniprot id: A0A172RY48
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04265
gene id: 79604:AAY81_RS04265
uniprot id: A0A172RXX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

79604:AAY81 RS08210
gene id: 79604:AAY81_RS08210
uniprot id: A0A172RZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

79604:AAY81 RS08355
gene id: 79604:AAY81_RS08355
uniprot id: A0A172RZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS00210
gene id: 79604:AAY81_RS00210
uniprot id: A0A172RVV2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

79604:AAY81 RS08260
gene id: 79604:AAY81_RS08260
uniprot id: A0A1H8QG60
names: Similarity
messages: Belongs to the peptidase S8 family.

79604:AAY81 RS08250
gene id: 79604:AAY81_RS08250
uniprot id: A0A172RZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

79604:AAY81 RS03000
gene id: 79604:AAY81_RS03000
uniprot id: A0A172RX25
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05510
gene id: 79604:AAY81_RS05510
uniprot id: A0A172RY69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

79604:AAY81 RS08760
gene id: 79604:AAY81_RS08760
uniprot id: A0A172RZV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

79604:AAY81 RS02625
gene id: 79604:AAY81_RS02625
uniprot id: A0A172RWU1
names: Similarity
messages: Belongs to the peptidase M13 family.

79604:AAY81 RS09850
gene id: 79604:AAY81_RS09850
uniprot id: A0A172S028
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

79604:AAY81 RS02015
gene id: 79604:AAY81_RS02015
uniprot id: A0A172RWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

79604:AAY81 RS07105
gene id: 79604:AAY81_RS07105
uniprot id: A0A172RZ84
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

79604:AAY81 RS02910
gene id: 79604:AAY81_RS02910
uniprot id: A0A172RWY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS09840
gene id: 79604:AAY81_RS09840
uniprot id: A0A172S066
names: Similarity
messages: Belongs to the DDAH family.

79604:AAY81 RS03635
gene id: 79604:AAY81_RS03635
uniprot id: A0A172RXE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS02305
gene id: 79604:AAY81_RS02305
uniprot id: A0A172RX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

79604:AAY81 RS05930
gene id: 79604:AAY81_RS05930
uniprot id: A0A172RYE6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

79604:AAY81 RS00335
gene id: 79604:AAY81_RS00335
uniprot id: A0A172RVX2
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05780
gene id: 79604:AAY81_RS05780
uniprot id: A0A172RYE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

79604:AAY81 RS08575
gene id: 79604:AAY81_RS08575
uniprot id: A0A172RZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

79604:AAY81 RS03675
gene id: 79604:AAY81_RS03675
uniprot id: A0A172RXN2
names: Similarity
messages: Belongs to the XseB family.

79604:AAY81 RS01730
gene id: 79604:AAY81_RS01730
uniprot id: A0A172RWQ6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01495
gene id: 79604:AAY81_RS01495
uniprot id: A0A172RWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

79604:AAY81 RS06045
gene id: 79604:AAY81_RS06045
uniprot id: A0A172RYG7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

79604:AAY81 RS04215
gene id: 79604:AAY81_RS04215
uniprot id: A0A172RXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

79604:AAY81 RS06405
gene id: 79604:AAY81_RS06405
uniprot id: A0A172RYM9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

79604:AAY81 RS00590
gene id: 79604:AAY81_RS00590
uniprot id: A0A172RW90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

79604:AAY81 RS01090
gene id: 79604:AAY81_RS01090
uniprot id: A0A172RW83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

79604:AAY81 RS02755
gene id: 79604:AAY81_RS02755
uniprot id: A0A172RWZ2
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

79604:AAY81 RS02905
gene id: 79604:AAY81_RS02905
uniprot id: A0A172RX13
names: Similarity
messages: Belongs to the UDPGP type 2 family.

79604:AAY81 RS00700
gene id: 79604:AAY81_RS00700
uniprot id: A0A172RW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

79604:AAY81 RS07190
gene id: 79604:AAY81_RS07190
uniprot id: A0A172RZ50
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

79604:AAY81 RS00550
gene id: 79604:AAY81_RS00550
uniprot id: A0A172RW02
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

79604:AAY81 RS08205
gene id: 79604:AAY81_RS08205
uniprot id: A0A172RZQ6
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

79604:AAY81 RS00080
gene id: 79604:AAY81_RS00080
uniprot id: A0A172RVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS03555
gene id: 79604:AAY81_RS03555
uniprot id: A0A172RXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

79604:AAY81 RS08240
gene id: 79604:AAY81_RS08240
uniprot id: A0A172RZD7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

79604:AAY81 RS01990
gene id: 79604:AAY81_RS01990
uniprot id: A0A172RWV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS09180
gene id: 79604:AAY81_RS09180
uniprot id: A0A172S018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

79604:AAY81 RS05660
gene id: 79604:AAY81_RS05660
uniprot id: A0A172RY98
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS09275
gene id: 79604:AAY81_RS09275
uniprot id: A0A172S016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

79604:AAY81 RS01465
gene id: 79604:AAY81_RS01465
uniprot id: A0A172RWM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

79604:AAY81 RS05115
gene id: 79604:AAY81_RS05115
uniprot id: A0A172RY14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

79604:AAY81 RS01035
gene id: 79604:AAY81_RS01035
uniprot id: A0A172RW80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

79604:AAY81 RS00055
gene id: 79604:AAY81_RS00055
uniprot id: A0A172RW39
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06060
gene id: 79604:AAY81_RS06060
uniprot id: A0A172RYF7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

79604:AAY81 RS05970
gene id: 79604:AAY81_RS05970
uniprot id: A0A172RYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

79604:AAY81 RS09460
gene id: 79604:AAY81_RS09460
uniprot id: A0A172RZX6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

79604:AAY81 RS03335
gene id: 79604:AAY81_RS03335
uniprot id: A0A1H8R4S3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05925
gene id: 79604:AAY81_RS05925
uniprot id: A0A172RYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

79604:AAY81 RS04260
gene id: 79604:AAY81_RS04260
uniprot id: A0A172RXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

79604:AAY81 RS09505
gene id: 79604:AAY81_RS09505
uniprot id: A0A172RZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

79604:AAY81 RS07870
gene id: 79604:AAY81_RS07870
uniprot id: A0A172RZK4
names: Similarity
messages: Belongs to the UPF0145 family.

79604:AAY81 RS06515
gene id: 79604:AAY81_RS06515
uniprot id: A0A172RYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

79604:AAY81 RS08395
gene id: 79604:AAY81_RS08395
uniprot id: A0A172RZI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

79604:AAY81 RS04405
gene id: 79604:AAY81_RS04405
uniprot id: A0A172RXN9
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05095
gene id: 79604:AAY81_RS05095
uniprot id: A0A172RY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

79604:AAY81 RS09780
gene id: 79604:AAY81_RS09780
uniprot id: A0A172S019
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

79604:AAY81 RS09370
gene id: 79604:AAY81_RS09370
uniprot id: A0A172RZW5
names: Similarity
messages: Belongs to the Fur family.

79604:AAY81 RS04150
gene id: 79604:AAY81_RS04150
uniprot id: A0A172RXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

79604:AAY81 RS01785
gene id: 79604:AAY81_RS01785
uniprot id: A0A172RWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

79604:AAY81 RS05745
gene id: 79604:AAY81_RS05745
uniprot id: A0A172RYC2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

79604:AAY81 RS06560
gene id: 79604:AAY81_RS06560
uniprot id: A0A172RYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

79604:AAY81 RS09135
gene id: 79604:AAY81_RS09135
uniprot id: A0A172RZV3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

79604:AAY81 RS07020
gene id: 79604:AAY81_RS07020
uniprot id: A0A172RYU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

79604:AAY81 RS05390
gene id: 79604:AAY81_RS05390
uniprot id: A0A172RY80
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

79604:AAY81 RS04170
gene id: 79604:AAY81_RS04170
uniprot id: A0A172RXM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

79604:AAY81 RS03005
gene id: 79604:AAY81_RS03005
uniprot id: A0A172RX35
names: Similarity
messages: Belongs to the agmatine deiminase family.

79604:AAY81 RS04525
gene id: 79604:AAY81_RS04525
uniprot id: A0A172RXQ9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

79604:AAY81 RS04565
gene id: 79604:AAY81_RS04565
uniprot id: A0A172RXS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS02575
gene id: 79604:AAY81_RS02575
uniprot id: A0A172RX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

79604:AAY81 RS01490
gene id: 79604:AAY81_RS01490
uniprot id: A0A172RWF0
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07220
gene id: 79604:AAY81_RS07220
uniprot id: A0A172RYY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

79604:AAY81 RS04540
gene id: 79604:AAY81_RS04540
uniprot id: A0A172RY19
names: Similarity
messages: Belongs to the thioredoxin family.

79604:AAY81 RS08645
gene id: 79604:AAY81_RS08645
uniprot id: A0A172RZM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

79604:AAY81 RS09055
gene id: 79604:AAY81_RS09055
uniprot id: A0A172RZT9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

79604:AAY81 RS02340
gene id: 79604:AAY81_RS02340
uniprot id: A0A1H8SWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

79604:AAY81 RS02065
gene id: 79604:AAY81_RS02065
uniprot id: A0A172RWV9
names: Similarity
messages: Belongs to the fabD family.

79604:AAY81 RS01395
gene id: 79604:AAY81_RS01395
uniprot id: A0A172RWL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS03010
gene id: 79604:AAY81_RS03010
uniprot id: A0A172RX20
names: Similarity
messages: Belongs to the carbamate kinase family.

79604:AAY81 RS06920
gene id: 79604:AAY81_RS06920
uniprot id: A0A172S0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

79604:AAY81 RS06910
gene id: 79604:AAY81_RS06910
uniprot id: A0A172RZ12
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

79604:AAY81 RS05720
gene id: 79604:AAY81_RS05720
uniprot id: A0A172RY95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS01945
gene id: 79604:AAY81_RS01945
uniprot id: A0A172RWM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

79604:AAY81 RS01575
gene id: 79604:AAY81_RS01575
uniprot id: A0A172RWP7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

79604:AAY81 RS05755
gene id: 79604:AAY81_RS05755
uniprot id: A0A172RYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

79604:AAY81 RS00755
gene id: 79604:AAY81_RS00755
uniprot id: A0A172RW35
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07950
gene id: 79604:AAY81_RS07950
uniprot id: A0A172RZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS05670
gene id: 79604:AAY81_RS05670
uniprot id: A0A172RY88
names: Similarity
messages: Belongs to the phosphohexose mutase family.

79604:AAY81 RS02475
gene id: 79604:AAY81_RS02475
uniprot id: A0A172RWU5
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06960
gene id: 79604:AAY81_RS06960
uniprot id: A0A1H8RYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

79604:AAY81 RS04595
gene id: 79604:AAY81_RS04595
uniprot id: A0A172RY27
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

79604:AAY81 RS07805
gene id: 79604:AAY81_RS07805
uniprot id: A0A172RZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

79604:AAY81 RS04635
gene id: 79604:AAY81_RS04635
uniprot id: A0A172RXT3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

79604:AAY81 RS06275
gene id: 79604:AAY81_RS06275
uniprot id: A0A172RYK9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

79604:AAY81 RS02770
gene id: 79604:AAY81_RS02770
uniprot id: A0A1H8RC67
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

79604:AAY81 RS08885
gene id: 79604:AAY81_RS08885
uniprot id: A0A172RZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS07175
gene id: 79604:AAY81_RS07175
uniprot id: A0A172RZ26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

79604:AAY81 RS01520
gene id: 79604:AAY81_RS01520
uniprot id: A0A172RWR4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

79604:AAY81 RS06130
gene id: 79604:AAY81_RS06130
uniprot id: A0A172RYK7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

79604:AAY81 RS00575
gene id: 79604:AAY81_RS00575
uniprot id: A0A172S0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

79604:AAY81 RS04270
gene id: 79604:AAY81_RS04270
uniprot id: A0A172RXS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

79604:AAY81 RS05450
gene id: 79604:AAY81_RS05450
uniprot id: A0A172RY58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

79604:AAY81 RS03820
gene id: 79604:AAY81_RS03820
uniprot id: A0A172RXG7
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS04095
gene id: 79604:AAY81_RS04095
uniprot id: A0A172RXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

79604:AAY81 RS07280
gene id: 79604:AAY81_RS07280
uniprot id: A0A172RYZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

79604:AAY81 RS07545
gene id: 79604:AAY81_RS07545
uniprot id: A0A172RZ41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

79604:AAY81 RS04225
gene id: 79604:AAY81_RS04225
uniprot id: A0A172RXM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

79604:AAY81 RS09935
gene id: 79604:AAY81_RS09935
uniprot id: A0A172S0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

79604:AAY81 RS03135
gene id: 79604:AAY81_RS03135
uniprot id: A0A172RX58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

79604:AAY81 RS08840
gene id: 79604:AAY81_RS08840
uniprot id: A0A172RZW8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

79604:AAY81 RS02510
gene id: 79604:AAY81_RS02510
uniprot id: A0A172RWV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04590
gene id: 79604:AAY81_RS04590
uniprot id: A0A172RXU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

79604:AAY81 RS06040
gene id: 79604:AAY81_RS06040
uniprot id: A0A172RYE4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS05110
gene id: 79604:AAY81_RS05110
uniprot id: A0A172RY17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

79604:AAY81 RS04490
gene id: 79604:AAY81_RS04490
uniprot id: A0A172RXV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

79604:AAY81 RS02980
gene id: 79604:AAY81_RS02980
uniprot id: A0A1H8R9J7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS05260
gene id: 79604:AAY81_RS05260
uniprot id: A0A172RYD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS01065
gene id: 79604:AAY81_RS01065
uniprot id: A0A172RWF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

79604:AAY81 RS04705
gene id: 79604:AAY81_RS04705
uniprot id: A0A172RXT4
names: Similarity
messages: Belongs to the UPF0047 family.

79604:AAY81 RS07410
gene id: 79604:AAY81_RS07410
uniprot id: A0A172RZ68
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

79604:AAY81 RS02390
gene id: 79604:AAY81_RS02390
uniprot id: A0A172RX11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS02740
gene id: 79604:AAY81_RS02740
uniprot id: A0A172RWY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

79604:AAY81 RS02580
gene id: 79604:AAY81_RS02580
uniprot id: A0A172RX30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

79604:AAY81 RS01105
gene id: 79604:AAY81_RS01105
uniprot id: A0A172RW89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

79604:AAY81 RS07830
gene id: 79604:AAY81_RS07830
uniprot id: A0A172RZ94
names: Subcellular Location Annotation
messages: Cytoplasm

79604:AAY81 RS02940
gene id: 79604:AAY81_RS02940
uniprot id: A0A172RX88
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS00385
gene id: 79604:AAY81_RS00385
uniprot id: A0A172RW48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

79604:AAY81 RS06985
gene id: 79604:AAY81_RS06985
uniprot id: A0A172RYU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

79604:AAY81 RS06940
gene id: 79604:AAY81_RS06940
uniprot id: A0A172RYU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS05500
gene id: 79604:AAY81_RS05500
uniprot id: A0A172RY77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS02210
gene id: 79604:AAY81_RS02210
uniprot id: A0A172RWR1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

79604:AAY81 RS07495
gene id: 79604:AAY81_RS07495
uniprot id: A0A172RZ33
names: Similarity
messages: Belongs to the citrate synthase family.

79604:AAY81 RS08640
gene id: 79604:AAY81_RS08640
uniprot id: A0A172RZK6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

79604:AAY81 RS07230
gene id: 79604:AAY81_RS07230
uniprot id: A0A172RZ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

79604:AAY81 RS07835
gene id: 79604:AAY81_RS07835
uniprot id: A0A1H8Q9M5
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

79604:AAY81 RS04370
gene id: 79604:AAY81_RS04370
uniprot id: A0A1H8SMT3
names: Similarity
messages: Belongs to the Ahb/Nir family.

79604:AAY81 RS06250
gene id: 79604:AAY81_RS06250
uniprot id: A0A172RYI6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06965
gene id: 79604:AAY81_RS06965
uniprot id: A0A172RZ60
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS06705
gene id: 79604:AAY81_RS06705
uniprot id: A0A172RYY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

79604:AAY81 RS10720
gene id: 79604:AAY81_RS10720
uniprot id: A0A172RZR3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS01545
gene id: 79604:AAY81_RS01545
uniprot id: A0A172RWG0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

79604:AAY81 RS06155
gene id: 79604:AAY81_RS06155
uniprot id: A0A172RYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

79604:AAY81 RS05085
gene id: 79604:AAY81_RS05085
uniprot id: A0A172RY45
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

79604:AAY81 RS01190
gene id: 79604:AAY81_RS01190
uniprot id: A0A172RWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS09340
gene id: 79604:AAY81_RS09340
uniprot id: A0A172S024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

79604:AAY81 RS05460
gene id: 79604:AAY81_RS05460
uniprot id: A0A172RY90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

79604:AAY81 RS04220
gene id: 79604:AAY81_RS04220
uniprot id: A0A172RXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

79604:AAY81 RS07705
gene id: 79604:AAY81_RS07705
uniprot id: A0A172RZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

79604:AAY81 RS00455
gene id: 79604:AAY81_RS00455
uniprot id: A0A172RW07
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

79604:AAY81 RS00395
gene id: 79604:AAY81_RS00395
uniprot id: A0A172RVZ8
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

79604:AAY81 RS01420
gene id: 79604:AAY81_RS01420
uniprot id: A0A172RWE0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS06510
gene id: 79604:AAY81_RS06510
uniprot id: A0A172RYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

79604:AAY81 RS08475
gene id: 79604:AAY81_RS08475
uniprot id: A0A172RZV6
names: Similarity
messages: Belongs to the AOR/FOR family.

79604:AAY81 RS01175
gene id: 79604:AAY81_RS01175
uniprot id: A0A172RW98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS07305
gene id: 79604:AAY81_RS07305
uniprot id: A0A172RZ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

79604:AAY81 RS01890
gene id: 79604:AAY81_RS01890
uniprot id: A0A172RWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS07735
gene id: 79604:AAY81_RS07735
uniprot id: A0A172RZE2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS06585
gene id: 79604:AAY81_RS06585
uniprot id: A0A172RYW2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS01225
gene id: 79604:AAY81_RS01225
uniprot id: A0A172RWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

79604:AAY81 RS03735
gene id: 79604:AAY81_RS03735
uniprot id: A0A172RXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

79604:AAY81 RS06300
gene id: 79604:AAY81_RS06300
uniprot id: A0A172S0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS06915
gene id: 79604:AAY81_RS06915
uniprot id: A0A172RYV9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

79604:AAY81 RS06460
gene id: 79604:AAY81_RS06460
uniprot id: A0A172RYN9
names: Similarity
messages: Belongs to the class-I fumarase family.

79604:AAY81 RS01605
gene id: 79604:AAY81_RS01605
uniprot id: A0A172RWH0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

79604:AAY81 RS05160
gene id: 79604:AAY81_RS05160
uniprot id: A0A172RY08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

79604:AAY81 RS05840
gene id: 79604:AAY81_RS05840
uniprot id: A0A172RYF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

79604:AAY81 RS02205
gene id: 79604:AAY81_RS02205
uniprot id: A0A172RWQ5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

79604:AAY81 RS06895
gene id: 79604:AAY81_RS06895
uniprot id: A0A172RYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

79604:AAY81 RS08810
gene id: 79604:AAY81_RS08810
uniprot id: A0A172RZM2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

79604:AAY81 RS07180
gene id: 79604:AAY81_RS07180
uniprot id: A0A172RZ95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

79604:AAY81 RS02645
gene id: 79604:AAY81_RS02645
uniprot id: A0A172RX50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

79604:AAY81 RS00205
gene id: 79604:AAY81_RS00205
uniprot id: A0A172RVV1
names: Similarity
messages: Belongs to the IMPACT family.

79604:AAY81 RS06245
gene id: 79604:AAY81_RS06245
uniprot id: A0A172RYI2
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06830
gene id: 79604:AAY81_RS06830
uniprot id: A0A172RZ02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS01160
gene id: 79604:AAY81_RS01160
uniprot id: A0A172RWA1
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

79604:AAY81 RS02955
gene id: 79604:AAY81_RS02955
uniprot id: A0A172RX10
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate.

79604:AAY81 RS01235
gene id: 79604:AAY81_RS01235
uniprot id: A0A172RW97
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS03040
gene id: 79604:AAY81_RS03040
uniprot id: A0A172RXD8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

79604:AAY81 RS04280
gene id: 79604:AAY81_RS04280
uniprot id: A0A172RXN7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

79604:AAY81 RS06605
gene id: 79604:AAY81_RS06605
uniprot id: A0A172RYQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

79604:AAY81 RS07550
gene id: 79604:AAY81_RS07550
uniprot id: A0A172RZ48
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

79604:AAY81 RS06170
gene id: 79604:AAY81_RS06170
uniprot id: A0A172RYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

79604:AAY81 RS06850
gene id: 79604:AAY81_RS06850
uniprot id: A0A172RYU4
names: Similarity
messages: Belongs to the ArsC family.

79604:AAY81 RS04560
gene id: 79604:AAY81_RS04560
uniprot id: A0A172RXR2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

79604:AAY81 RS06995
gene id: 79604:AAY81_RS06995
uniprot id: A0A172RYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

79604:AAY81 RS07260
gene id: 79604:AAY81_RS07260
uniprot id: A0A172RZ01
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

79604:AAY81 RS00235
gene id: 79604:AAY81_RS00235
uniprot id: A0A172RVX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

79604:AAY81 RS03490
gene id: 79604:AAY81_RS03490
uniprot id: A0A172RXH2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

79604:AAY81 RS06120
gene id: 79604:AAY81_RS06120
uniprot id: A0A172RYG1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

79604:AAY81 RS03610
gene id: 79604:AAY81_RS03610
uniprot id: A0A172RXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

79604:AAY81 RS00130
gene id: 79604:AAY81_RS00130
uniprot id: A0A172RW12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

79604:AAY81 RS01695
gene id: 79604:AAY81_RS01695
uniprot id: A0A172RWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

79604:AAY81 RS07420
gene id: 79604:AAY81_RS07420
uniprot id: A0A172RZ39
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

79604:AAY81 RS05825
gene id: 79604:AAY81_RS05825
uniprot id: A0A172RYC7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

79604:AAY81 RS01995
gene id: 79604:AAY81_RS01995
uniprot id: A0A172RWU8
names: Similarity
messages: Belongs to the TrpC family.

79604:AAY81 RS01855
gene id: 79604:AAY81_RS01855
uniprot id: A0A172RWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

79604:AAY81 RS07250
gene id: 79604:AAY81_RS07250
uniprot id: A0A172RZ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

79604:AAY81 RS08700
gene id: 79604:AAY81_RS08700
uniprot id: A0A172RZL8
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS04275
gene id: 79604:AAY81_RS04275
uniprot id: A0A172RXU6
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

79604:AAY81 RS03530
gene id: 79604:AAY81_RS03530
uniprot id: A0A172RX86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

79604:AAY81 RS08170
gene id: 79604:AAY81_RS08170
uniprot id: A0A172RZE6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

79604:AAY81 RS07155
gene id: 79604:AAY81_RS07155
uniprot id: A0A172RYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS02435
gene id: 79604:AAY81_RS02435
uniprot id: A0A172RWU3
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

79604:AAY81 RS07890
gene id: 79604:AAY81_RS07890
uniprot id: A0A172RZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

79604:AAY81 RS07320
gene id: 79604:AAY81_RS07320
uniprot id: A0A172RZ18
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07310
gene id: 79604:AAY81_RS07310
uniprot id: A0A172RYZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

79604:AAY81 RS05370
gene id: 79604:AAY81_RS05370
uniprot id: A0A172RY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

79604:AAY81 RS08825
gene id: 79604:AAY81_RS08825
uniprot id: A0A172S005
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

79604:AAY81 RS01840
gene id: 79604:AAY81_RS01840
uniprot id: A0A172RWW3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

79604:AAY81 RS09545
gene id: 79604:AAY81_RS09545
uniprot id: A0A172S0C0
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06525
gene id: 79604:AAY81_RS06525
uniprot id: A0A172RYV2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

79604:AAY81 RS06285
gene id: 79604:AAY81_RS06285
uniprot id: A0A172RYI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

79604:AAY81 RS05140
gene id: 79604:AAY81_RS05140
uniprot id: A0A172RYB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS02995
gene id: 79604:AAY81_RS02995
uniprot id: A0A172RX96
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

79604:AAY81 RS07255
gene id: 79604:AAY81_RS07255
uniprot id: A0A172RYY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

79604:AAY81 RS06455
gene id: 79604:AAY81_RS06455
uniprot id: A0A172RYU2
names: Similarity
messages: Belongs to the class-I fumarase family.

79604:AAY81 RS02935
gene id: 79604:AAY81_RS02935
uniprot id: A0A172RX87
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

79604:AAY81 RS07955
gene id: 79604:AAY81_RS07955
uniprot id: A0A172RZB5
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS08675
gene id: 79604:AAY81_RS08675
uniprot id: A0A172RZY6
names: Similarity
messages: Belongs to the peptidase S8 family.

79604:AAY81 RS04245
gene id: 79604:AAY81_RS04245
uniprot id: A0A172RXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

79604:AAY81 RS06685
gene id: 79604:AAY81_RS06685
uniprot id: A0A172RYU7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

79604:AAY81 RS07515
gene id: 79604:AAY81_RS07515
uniprot id: A0A172RZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

79604:AAY81 RS01770
gene id: 79604:AAY81_RS01770
uniprot id: A0A172RWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

79604:AAY81 RS01570
gene id: 79604:AAY81_RS01570
uniprot id: A0A172RWS8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

79604:AAY81 RS03600
gene id: 79604:AAY81_RS03600
uniprot id: A0A1H8TT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

79604:AAY81 RS10315
gene id: 79604:AAY81_RS10315
uniprot id: A0A1H8PJB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

79604:AAY81 RS05090
gene id: 79604:AAY81_RS05090
uniprot id: A0A172RY72
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

79604:AAY81 RS01120
gene id: 79604:AAY81_RS01120
uniprot id: A0A172RW99
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS06270
gene id: 79604:AAY81_RS06270
uniprot id: A0A172RYQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS02000
gene id: 79604:AAY81_RS02000
uniprot id: A0A172RWM8
names: Similarity
messages: Belongs to the TrpF family.

79604:AAY81 RS03645
gene id: 79604:AAY81_RS03645
uniprot id: A0A172RXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

79604:AAY81 RS07435
gene id: 79604:AAY81_RS07435
uniprot id: A0A172RZ29
names: Similarity
messages: Belongs to the NAD synthetase family.

79604:AAY81 RS05545
gene id: 79604:AAY81_RS05545
uniprot id: A0A172RYB8
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS09105
gene id: 79604:AAY81_RS09105
uniprot id: A0A172S008
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

79604:AAY81 RS01460
gene id: 79604:AAY81_RS01460
uniprot id: A0A172RWQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

79604:AAY81 RS01085
gene id: 79604:AAY81_RS01085
uniprot id: A0A172RW91
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07205
gene id: 79604:AAY81_RS07205
uniprot id: A0A172RYZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

79604:AAY81 RS02950
gene id: 79604:AAY81_RS02950
uniprot id: A0A172RX23
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
messages: Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04515
gene id: 79604:AAY81_RS04515
uniprot id: A0A172RXR0
names: Similarity
messages: Belongs to the glutamine synthetase family.

79604:AAY81 RS09450
gene id: 79604:AAY81_RS09450
uniprot id: A0A172RZY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS08385
gene id: 79604:AAY81_RS08385
uniprot id: A0A172RZG9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

79604:AAY81 RS00350
gene id: 79604:AAY81_RS00350
uniprot id: A0A172RVZ6
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05940
gene id: 79604:AAY81_RS05940
uniprot id: A0A172RYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

79604:AAY81 RS02225
gene id: 79604:AAY81_RS02225
uniprot id: A0A172RWR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

79604:AAY81 RS06125
gene id: 79604:AAY81_RS06125
uniprot id: A0A172RYG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

79604:AAY81 RS05485
gene id: 79604:AAY81_RS05485
uniprot id: A0A172RY86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

79604:AAY81 RS05155
gene id: 79604:AAY81_RS05155
uniprot id: A0A172RY31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

79604:AAY81 RS08780
gene id: 79604:AAY81_RS08780
uniprot id: A0A172RZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

79604:AAY81 RS07860
gene id: 79604:AAY81_RS07860
uniprot id: A0A172RZ69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS07730
gene id: 79604:AAY81_RS07730
uniprot id: A0A172RZB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

79604:AAY81 RS01390
gene id: 79604:AAY81_RS01390
uniprot id: A0A172RWP2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

79604:AAY81 RS01955
gene id: 79604:AAY81_RS01955
uniprot id: A0A1H8T2D3
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

79604:AAY81 RS09835
gene id: 79604:AAY81_RS09835
uniprot id: A0A172S041
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

79604:AAY81 RS07185
gene id: 79604:AAY81_RS07185
uniprot id: A0A172RZ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

79604:AAY81 RS03190
gene id: 79604:AAY81_RS03190
uniprot id: A0A172RX67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

79604:AAY81 RS05915
gene id: 79604:AAY81_RS05915
uniprot id: A0A172RYF0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

79604:AAY81 RS07245
gene id: 79604:AAY81_RS07245
uniprot id: A0A172RZ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

79604:AAY81 RS08065
gene id: 79604:AAY81_RS08065
uniprot id: A0A172RZN8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

79604:AAY81 RS07240
gene id: 79604:AAY81_RS07240
uniprot id: A0A172RZ36
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

79604:AAY81 RS07215
gene id: 79604:AAY81_RS07215
uniprot id: A0A172RYY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

79604:AAY81 RS02235
gene id: 79604:AAY81_RS02235
uniprot id: A0A172RWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

79604:AAY81 RS07110
gene id: 79604:AAY81_RS07110
uniprot id: A0A172RZ15
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

79604:AAY81 RS02070
gene id: 79604:AAY81_RS02070
uniprot id: A0A172RWN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

79604:AAY81 RS04600
gene id: 79604:AAY81_RS04600
uniprot id: A0A172RXW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

79604:AAY81 RS09660
gene id: 79604:AAY81_RS09660
uniprot id: A0A172S0E4
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07090
gene id: 79604:AAY81_RS07090
uniprot id: A0A172RYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS07390
gene id: 79604:AAY81_RS07390
uniprot id: A0A172RZ13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS08135
gene id: 79604:AAY81_RS08135
uniprot id: A0A172RZH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

79604:AAY81 RS08005
gene id: 79604:AAY81_RS08005
uniprot id: A0A172RZM4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS06930
gene id: 79604:AAY81_RS06930
uniprot id: A0A172RYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

79604:AAY81 RS00715
gene id: 79604:AAY81_RS00715
uniprot id: A0A172RWB3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

79604:AAY81 RS05785
gene id: 79604:AAY81_RS05785
uniprot id: A0A172RYL8
names: Similarity
messages: Belongs to the peptidase S8 family.

79604:AAY81 RS06150
gene id: 79604:AAY81_RS06150
uniprot id: A0A172RYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

79604:AAY81 RS00885
gene id: 79604:AAY81_RS00885
uniprot id: A0A1H8UJZ3
names: Similarity
messages: Belongs to the peptidase S14 family.

79604:AAY81 RS01400
gene id: 79604:AAY81_RS01400
uniprot id: A0A172RWK5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS01680
gene id: 79604:AAY81_RS01680
uniprot id: A0A172RWI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

79604:AAY81 RS01565
gene id: 79604:AAY81_RS01565
uniprot id: A0A172RWG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

79604:AAY81 RS01685
gene id: 79604:AAY81_RS01685
uniprot id: A0A172RWH4
names: Similarity
messages: Belongs to the GARS family.

79604:AAY81 RS07695
gene id: 79604:AAY81_RS07695
uniprot id: A0A172RZ62
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

79604:AAY81 RS10635
gene id: 79604:AAY81_RS10635
uniprot id: A0A172RZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

79604:AAY81 RS02385
gene id: 79604:AAY81_RS02385
uniprot id: A0A172RX45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS06610
gene id: 79604:AAY81_RS06610
uniprot id: A0A1H8RT70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

79604:AAY81 RS02895
gene id: 79604:AAY81_RS02895
uniprot id: A0A172RX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

79604:AAY81 RS07235
gene id: 79604:AAY81_RS07235
uniprot id: A0A172RZA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

79604:AAY81 RS10630
gene id: 79604:AAY81_RS10630
uniprot id: A0A172RZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

79604:AAY81 RS09205
gene id: 79604:AAY81_RS09205
uniprot id: A0A172RZT4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

79604:AAY81 RS02455
gene id: 79604:AAY81_RS02455
uniprot id: A0A172RX21
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

79604:AAY81 RS05920
gene id: 79604:AAY81_RS05920
uniprot id: A0A172RYC1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

79604:AAY81 RS07810
gene id: 79604:AAY81_RS07810
uniprot id: A0A172RZC8
names: Similarity
messages: Belongs to the asparagine synthetase family.

79604:AAY81 RS05495
gene id: 79604:AAY81_RS05495
uniprot id: A0A172RY73
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

79604:AAY81 RS05365
gene id: 79604:AAY81_RS05365
uniprot id: A0A172RY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

79604:AAY81 RS05675
gene id: 79604:AAY81_RS05675
uniprot id: A0A172RYC9
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS04555
gene id: 79604:AAY81_RS04555
uniprot id: A0A172RXS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

79604:AAY81 RS05360
gene id: 79604:AAY81_RS05360
uniprot id: A0A172RY65
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

79604:AAY81 RS05335
gene id: 79604:AAY81_RS05335
uniprot id: A0A172RY70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

79604:AAY81 RS04390
gene id: 79604:AAY81_RS04390
uniprot id: A0A172RXP6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

79604:AAY81 RS08115
gene id: 79604:AAY81_RS08115
uniprot id: A0A172RZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

79604:AAY81 RS02195
gene id: 79604:AAY81_RS02195
uniprot id: A0A172RWQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

79604:AAY81 RS08765
gene id: 79604:AAY81_RS08765
uniprot id: A0A172RZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

79604:AAY81 RS05490
gene id: 79604:AAY81_RS05490
uniprot id: A0A172RY51
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

79604:AAY81 RS04360
gene id: 79604:AAY81_RS04360
uniprot id: A0A172RXP9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

79604:AAY81 RS05350
gene id: 79604:AAY81_RS05350
uniprot id: A0A172RY84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

79604:AAY81 RS05230
gene id: 79604:AAY81_RS05230
uniprot id: A0A172RY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

79604:AAY81 RS03665
gene id: 79604:AAY81_RS03665
uniprot id: A0A172RXE3
names: Similarity
messages: Belongs to the asp23 family.

79604:AAY81 RS01645
gene id: 79604:AAY81_RS01645
uniprot id: A0A172RWH5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

79604:AAY81 RS05245
gene id: 79604:AAY81_RS05245
uniprot id: A0A172RY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

79604:AAY81 RS08060
gene id: 79604:AAY81_RS08060
uniprot id: A0A172RZG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS04145
gene id: 79604:AAY81_RS04145
uniprot id: A0A172RXJ7
names: Similarity
messages: Belongs to the peptidase S41A family.

79604:AAY81 RS04140
gene id: 79604:AAY81_RS04140
uniprot id: A0A172RXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

79604:AAY81 RS00120
gene id: 79604:AAY81_RS00120
uniprot id: A0A172RW51
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

79604:AAY81 RS06570
gene id: 79604:AAY81_RS06570
uniprot id: A0A172RYS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

79604:AAY81 RS04760
gene id: 79604:AAY81_RS04760
uniprot id: A0A172RXV1
names: Similarity
messages: Belongs to the ELP3 family.

79604:AAY81 RS04460
gene id: 79604:AAY81_RS04460
uniprot id: A0A172RXQ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

79604:AAY81 RS05415
gene id: 79604:AAY81_RS05415
uniprot id: A0A172RYC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

79604:AAY81 RS06135
gene id: 79604:AAY81_RS06135
uniprot id: A0A172RYS4
names: Similarity
messages: Belongs to the ribF family.

79604:AAY81 RS06035
gene id: 79604:AAY81_RS06035
uniprot id: A0A172RYH0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

79604:AAY81 RS06000
gene id: 79604:AAY81_RS06000
uniprot id: A0A172RYI5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

79604:AAY81 RS03625
gene id: 79604:AAY81_RS03625
uniprot id: A0A172RXJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

79604:AAY81 RS03045
gene id: 79604:AAY81_RS03045
uniprot id: A0A172RXA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

79604:AAY81 RS00240
gene id: 79604:AAY81_RS00240
uniprot id: A0A172RVX3
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05800
gene id: 79604:AAY81_RS05800
uniprot id: A0A172RYI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

79604:AAY81 RS09845
gene id: 79604:AAY81_RS09845
uniprot id: A0A172S031
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

79604:AAY81 RS06430
gene id: 79604:AAY81_RS06430
uniprot id: A0A172RYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

79604:AAY81 RS08165
gene id: 79604:AAY81_RS08165
uniprot id: A0A172RZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS03535
gene id: 79604:AAY81_RS03535
uniprot id: A0A172RXB9
names: Similarity
messages: Belongs to the UPF0045 family.

79604:AAY81 RS08775
gene id: 79604:AAY81_RS08775
uniprot id: A0A172RZM8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

79604:AAY81 RS06595
gene id: 79604:AAY81_RS06595
uniprot id: A0A172RYP0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

79604:AAY81 RS05730
gene id: 79604:AAY81_RS05730
uniprot id: A0A172RYK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS02880
gene id: 79604:AAY81_RS02880
uniprot id: A0A172RX79
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

79604:AAY81 RS00535
gene id: 79604:AAY81_RS00535
uniprot id: A0A172RW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS07795
gene id: 79604:AAY81_RS07795
uniprot id: A0A172RZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

79604:AAY81 RS08185
gene id: 79604:AAY81_RS08185
uniprot id: A0A172RZC3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

79604:AAY81 RS04480
gene id: 79604:AAY81_RS04480
uniprot id: A0A172RY10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

79604:AAY81 RS05220
gene id: 79604:AAY81_RS05220
uniprot id: A0A172RY43
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

79604:AAY81 RS03630
gene id: 79604:AAY81_RS03630
uniprot id: A0A172RXC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS05265
gene id: 79604:AAY81_RS05265
uniprot id: A0A1H8TKG8
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS03260
gene id: 79604:AAY81_RS03260
uniprot id: A0A172RX76
names: Similarity
messages: Belongs to the peptidase C59 family.

79604:AAY81 RS04035
gene id: 79604:AAY81_RS04035
uniprot id: A0A172RXI4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

79604:AAY81 RS02890
gene id: 79604:AAY81_RS02890
uniprot id: A0A172RX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

79604:AAY81 RS06955
gene id: 79604:AAY81_RS06955
uniprot id: A0A172RYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS01020
gene id: 79604:AAY81_RS01020
uniprot id: A0A172RW93
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

79604:AAY81 RS07315
gene id: 79604:AAY81_RS07315
uniprot id: A0A172RZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

79604:AAY81 RS02810
gene id: 79604:AAY81_RS02810
uniprot id: A0A172RX04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

79604:AAY81 RS09030
gene id: 79604:AAY81_RS09030
uniprot id: A0A172RZX1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

79604:AAY81 RS00245
gene id: 79604:AAY81_RS00245
uniprot id: A0A172RVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

79604:AAY81 RS09645
gene id: 79604:AAY81_RS09645
uniprot id: A0A172S003
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS00800
gene id: 79604:AAY81_RS00800
uniprot id: A0A172RW50
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

79604:AAY81 RS04085
gene id: 79604:AAY81_RS04085
uniprot id: A0A172RXK1
names: Similarity
messages: Belongs to the polypeptide deformylase family.

79604:AAY81 RS08375
gene id: 79604:AAY81_RS08375
uniprot id: A0A172RZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

79604:AAY81 RS06820
gene id: 79604:AAY81_RS06820
uniprot id: A0A172RYX5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

79604:AAY81 RS07165
gene id: 79604:AAY81_RS07165
uniprot id: A0A172RYX0
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

79604:AAY81 RS07300
gene id: 79604:AAY81_RS07300
uniprot id: A0A172RZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

79604:AAY81 RS08285
gene id: 79604:AAY81_RS08285
uniprot id: A0A172RZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

79604:AAY81 RS04295
gene id: 79604:AAY81_RS04295
uniprot id: A0A172RXN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

79604:AAY81 RS07125
gene id: 79604:AAY81_RS07125
uniprot id: A0A172RYY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

79604:AAY81 RS09870
gene id: 79604:AAY81_RS09870
uniprot id: A0A172S0H2
names: Similarity
messages: Belongs to the isochorismate synthase family.

79604:AAY81 RS05250
gene id: 79604:AAY81_RS05250
uniprot id: A0A172RY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

79604:AAY81 RS07075
gene id: 79604:AAY81_RS07075
uniprot id: A0A172RYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

79604:AAY81 RS02280
gene id: 79604:AAY81_RS02280
uniprot id: A0A172RWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

79604:AAY81 RS01125
gene id: 79604:AAY81_RS01125
uniprot id: A0A172RWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

79604:AAY81 RS05710
gene id: 79604:AAY81_RS05710
uniprot id: A0A172RYA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

79604:AAY81 RS05655
gene id: 79604:AAY81_RS05655
uniprot id: A0A172RY93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

79604:AAY81 RS02190
gene id: 79604:AAY81_RS02190
uniprot id: A0A172RWX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

79604:AAY81 RS08180
gene id: 79604:AAY81_RS08180
uniprot id: A0A1H8QEX0
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS08145
gene id: 79604:AAY81_RS08145
uniprot id: A0A172RZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

79604:AAY81 RS07285
gene id: 79604:AAY81_RS07285
uniprot id: A0A172RZ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

79604:AAY81 RS09555
gene id: 79604:AAY81_RS09555
uniprot id: A0A172S076
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS08245
gene id: 79604:AAY81_RS08245
uniprot id: A0A172RZD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS02075
gene id: 79604:AAY81_RS02075
uniprot id: A0A172RWP9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

79604:AAY81 RS02835
gene id: 79604:AAY81_RS02835
uniprot id: A0A172RX01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

79604:AAY81 RS03720
gene id: 79604:AAY81_RS03720
uniprot id: A0A172RXD9
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS07010
gene id: 79604:AAY81_RS07010
uniprot id: A0A172RYV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS07570
gene id: 79604:AAY81_RS07570
uniprot id: A0A172RZ43
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

79604:AAY81 RS06800
gene id: 79604:AAY81_RS06800
uniprot id: A0A172RYS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

79604:AAY81 RS01845
gene id: 79604:AAY81_RS01845
uniprot id: A0A172RWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

79604:AAY81 RS00150
gene id: 79604:AAY81_RS00150
uniprot id: A0A172RVU1
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05515
gene id: 79604:AAY81_RS05515
uniprot id: A0A172RYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

79604:AAY81 RS01740
gene id: 79604:AAY81_RS01740
uniprot id: A0A172RWK1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

79604:AAY81 RS07050
gene id: 79604:AAY81_RS07050
uniprot id: A0A1H8RZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

79604:AAY81 RS02745
gene id: 79604:AAY81_RS02745
uniprot id: A0A172RWZ9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

79604:AAY81 RS07535
gene id: 79604:AAY81_RS07535
uniprot id: A0A172RZB2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

79604:AAY81 RS01535
gene id: 79604:AAY81_RS01535
uniprot id: A0A172RWF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

79604:AAY81 RS04545
gene id: 79604:AAY81_RS04545
uniprot id: A0A172RXW0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

79604:AAY81 RS05990
gene id: 79604:AAY81_RS05990
uniprot id: A0A172RYE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

79604:AAY81 RS01775
gene id: 79604:AAY81_RS01775
uniprot id: A0A172RWJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

79604:AAY81 RS06115
gene id: 79604:AAY81_RS06115
uniprot id: A0A1H8SGK3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

79604:AAY81 RS03430
gene id: 79604:AAY81_RS03430
uniprot id: A0A172RXG2
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

79604:AAY81 RS05760
gene id: 79604:AAY81_RS05760
uniprot id: A0A172RYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

79604:AAY81 RS07295
gene id: 79604:AAY81_RS07295
uniprot id: A0A172RZ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

79604:AAY81 RS04415
gene id: 79604:AAY81_RS04415
uniprot id: A0A172RXZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

79604:AAY81 RS04465
gene id: 79604:AAY81_RS04465
uniprot id: A0A172RXQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS02050
gene id: 79604:AAY81_RS02050
uniprot id: A0A1H8T290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

79604:AAY81 RS07265
gene id: 79604:AAY81_RS07265
uniprot id: A0A172RZ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

79604:AAY81 RS02335
gene id: 79604:AAY81_RS02335
uniprot id: A0A172RWS7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

79604:AAY81 RS09520
gene id: 79604:AAY81_RS09520
uniprot id: A0A172RZY5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

79604:AAY81 RS00675
gene id: 79604:AAY81_RS00675
uniprot id: A0A172RW37
names: Similarity
messages: Belongs to the GSP E family.

79604:AAY81 RS00595
gene id: 79604:AAY81_RS00595
uniprot id: A0A172RW84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

79604:AAY81 RS04305
gene id: 79604:AAY81_RS04305
uniprot id: A0A172RXN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

79604:AAY81 RS06565
gene id: 79604:AAY81_RS06565
uniprot id: A0A172RYN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

79604:AAY81 RS06055
gene id: 79604:AAY81_RS06055
uniprot id: A0A172RYF1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

79604:AAY81 RS02265
gene id: 79604:AAY81_RS02265
uniprot id: A0A172RWS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

79604:AAY81 RS00345
gene id: 79604:AAY81_RS00345
uniprot id: A0A172RVW9
names: Subcellular Location Annotation
messages: Membrane

79604:AAY81 RS05340
gene id: 79604:AAY81_RS05340
uniprot id: A0A172RYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

79604:AAY81 RS08790
gene id: 79604:AAY81_RS08790
uniprot id: A0A172RZQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

79604:AAY81 RS04375
gene id: 79604:AAY81_RS04375
uniprot id: A0A172RXN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

79604:AAY81 RS05590
gene id: 79604:AAY81_RS05590
uniprot id: A0A172RY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

79604:AAY81 RS06440
gene id: 79604:AAY81_RS06440
uniprot id: A0A172RYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

79604:AAY81 RS05625
gene id: 79604:AAY81_RS05625
uniprot id: A0A172RYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

79604:AAY81 RS02160
gene id: 79604:AAY81_RS02160
uniprot id: A0A172RWQ1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

79604:AAY81 RS00105
gene id: 79604:AAY81_RS00105
uniprot id: A0A172RVT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

79604:AAY81 RS01615
gene id: 79604:AAY81_RS01615
uniprot id: A0A172RWG8
names: Similarity
messages: Belongs to the UPF0237 family.

79604:AAY81 RS04210
gene id: 79604:AAY81_RS04210
uniprot id: A0A172RXW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

79604:AAY81 RS00505
gene id: 79604:AAY81_RS00505
uniprot id: A0A172RWA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

79604:AAY81 RS05995
gene id: 79604:AAY81_RS05995
uniprot id: A0A172RYE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

79604:AAY81 RS04605
gene id: 79604:AAY81_RS04605
uniprot id: A0A172RXZ4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

79604:AAY81 RS02010
gene id: 79604:AAY81_RS02010
uniprot id: A0A172RWM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

79604:AAY81 RS05505
gene id: 79604:AAY81_RS05505
uniprot id: A0A172RY68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

79604:AAY81 RS08730
gene id: 79604:AAY81_RS08730
uniprot id: A0A172RZM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

79604:AAY81 RS00125
gene id: 79604:AAY81_RS00125
uniprot id: A0A172RW18
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

79604:AAY81 RS03660
gene id: 79604:AAY81_RS03660
uniprot id: A0A172RXB8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

79604:AAY81 RS02495
gene id: 79604:AAY81_RS02495
uniprot id: A0A172RWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

79604:AAY81 RS09315
gene id: 79604:AAY81_RS09315
uniprot id: A0A172RZW4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

79604:AAY81 RS05225
gene id: 79604:AAY81_RS05225
uniprot id: A0A172RY15
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

79604:AAY81 RS00430
gene id: 79604:AAY81_RS00430
uniprot id: A0A1H8PRR8
names: Subcellular Location Annotation
messages: Membrane