768679:TTX RS02585
gene id: 768679:TTX_RS02585
uniprot id: G4RNQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

768679:TTX RS04260
gene id: 768679:TTX_RS04260
uniprot id: G4RPP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

768679:TTX RS05975
gene id: 768679:TTX_RS05975
uniprot id: G4RJY8
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated protein Csa1 family.
messages: Binds 1 [4Fe-4S] cluster per subunit. May not be required for nuclease activity.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). A ssDNA exonuclease with 5' to 3' and perhaps 3' to 5' activity.
messages: Can form a Cascis complex with Cas4 and Csa1.
messages: Mn(2+) required for nuclease activity.
messages: Slightly induced by 20 J/m2 ultraviolet light. Member of the csa1-cas1/2-cas4 operon.

768679:TTX RS06770
gene id: 768679:TTX_RS06770
uniprot id: G4RKF1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

768679:TTX RS02315
gene id: 768679:TTX_RS02315
uniprot id: G4RNJ1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

768679:TTX RS01090
gene id: 768679:TTX_RS01090
uniprot id: G4RMU7
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS05250
gene id: 768679:TTX_RS05250
uniprot id: G4RJI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

768679:TTX RS00680
gene id: 768679:TTX_RS00680
uniprot id: G4RMH8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS09660
gene id: 768679:TTX_RS09660
uniprot id: G4RM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

768679:TTX RS08730
gene id: 768679:TTX_RS08730
uniprot id: G4RLI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

768679:TTX RS02725
gene id: 768679:TTX_RS02725
uniprot id: G4RNT1
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02540
gene id: 768679:TTX_RS02540
uniprot id: G4RNP2
names: Similarity
messages: Belongs to the NOP10 family.

768679:TTX RS03240
gene id: 768679:TTX_RS03240
uniprot id: G4RP35
names: Similarity
messages: Belongs to the DMRL synthase family.

768679:TTX RS00040
gene id: 768679:TTX_RS00040
uniprot id: G4RQ48
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS01795
gene id: 768679:TTX_RS01795
uniprot id: G4RN87
names: Similarity
messages: Belongs to the thioesterase PaaI family.

768679:TTX RS05410
gene id: 768679:TTX_RS05410
uniprot id: G4RJL8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS05470
gene id: 768679:TTX_RS05470
uniprot id: G4RJN0
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS01465
gene id: 768679:TTX_RS01465
uniprot id: G4RN21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

768679:TTX RS02420
gene id: 768679:TTX_RS02420
uniprot id: G4RNL6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

768679:TTX RS02400
gene id: 768679:TTX_RS02400
uniprot id: G4RNL2
names: Similarity
messages: Belongs to the HypE family.

768679:TTX RS00145
gene id: 768679:TTX_RS00145
uniprot id: G4RQ66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

768679:TTX RS01310
gene id: 768679:TTX_RS01310
uniprot id: G4RMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

768679:TTX RS03115
gene id: 768679:TTX_RS03115
uniprot id: G4RP10
names: Similarity
messages: Belongs to the SfsA family.

768679:TTX RS05270
gene id: 768679:TTX_RS05270
uniprot id: G4RJJ0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
messages: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

768679:TTX RS06820
gene id: 768679:TTX_RS06820
uniprot id: G4RKG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

768679:TTX RS08450
gene id: 768679:TTX_RS08450
uniprot id: G4RLC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS07280
gene id: 768679:TTX_RS07280
uniprot id: G4RKP8
names: Similarity
messages: Belongs to the malic enzymes family.

768679:TTX RS09665
gene id: 768679:TTX_RS09665
uniprot id: G4RM19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

768679:TTX RS06750
gene id: 768679:TTX_RS06750
uniprot id: G4RKE6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS01060
gene id: 768679:TTX_RS01060
uniprot id: G4RMU1
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS08035
gene id: 768679:TTX_RS08035
uniprot id: G4RL43
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

768679:TTX RS03300
gene id: 768679:TTX_RS03300
uniprot id: G4RP47
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

768679:TTX RS05025
gene id: 768679:TTX_RS05025
uniprot id: G4RQ41
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768679:TTX RS04870
gene id: 768679:TTX_RS04870
uniprot id: G4RQ12
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

768679:TTX RS10105
gene id: 768679:TTX_RS10105
uniprot id: G4RMM5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

768679:TTX RS00370
gene id: 768679:TTX_RS00370
uniprot id: G4RMB6
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS03270
gene id: 768679:TTX_RS03270
uniprot id: G4RP41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS01075
gene id: 768679:TTX_RS01075
uniprot id: G4RMU4
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS04450
gene id: 768679:TTX_RS04450
uniprot id: G4RPT1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

768679:TTX RS07430
gene id: 768679:TTX_RS07430
uniprot id: G4RKS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

768679:TTX RS08245
gene id: 768679:TTX_RS08245
uniprot id: G4RL86
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

768679:TTX RS09620
gene id: 768679:TTX_RS09620
uniprot id: G4RM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

768679:TTX RS06075
gene id: 768679:TTX_RS06075
uniprot id: G4RK10
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS09165
gene id: 768679:TTX_RS09165
uniprot id: G4RLR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS00340
gene id: 768679:TTX_RS00340
uniprot id: G4RMA9
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

768679:TTX RS06425
gene id: 768679:TTX_RS06425
uniprot id: G4RK83
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS08880
gene id: 768679:TTX_RS08880
uniprot id: G4RLL2
names: Similarity
messages: Belongs to the UPF0045 family.

768679:TTX RS08915
gene id: 768679:TTX_RS08915
uniprot id: G4RLL9
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04545
gene id: 768679:TTX_RS04545
uniprot id: G4RPV0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

768679:TTX RS09330
gene id: 768679:TTX_RS09330
uniprot id: G4RLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

768679:TTX RS06730
gene id: 768679:TTX_RS06730
uniprot id: G4RKE2
names: Similarity
messages: Belongs to the TrpF family.

768679:TTX RS06140
gene id: 768679:TTX_RS06140
uniprot id: G4RK23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08015
gene id: 768679:TTX_RS08015
uniprot id: G4RL39
names: Similarity
messages: Belongs to the UPF0179 family.

768679:TTX RS01145
gene id: 768679:TTX_RS01145
uniprot id: G4RMV8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS07465
gene id: 768679:TTX_RS07465
uniprot id: G4RKT6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

768679:TTX RS05435
gene id: 768679:TTX_RS05435
uniprot id: G4RJM3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

768679:TTX RS03165
gene id: 768679:TTX_RS03165
uniprot id: G4RP20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

768679:TTX RS02775
gene id: 768679:TTX_RS02775
uniprot id: G4RNU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768679:TTX RS00730
gene id: 768679:TTX_RS00730
uniprot id: G4RMI8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS05775
gene id: 768679:TTX_RS05775
uniprot id: G4RJU7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

768679:TTX RS00970
gene id: 768679:TTX_RS00970
uniprot id: G4RMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS09920
gene id: 768679:TTX_RS09920
uniprot id: G4RM68
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

768679:TTX RS02340
gene id: 768679:TTX_RS02340
uniprot id: G4RNJ8
names: Subcellular Location Annotation
messages: Encapsulin nanocompartment

768679:TTX RS09270
gene id: 768679:TTX_RS09270
uniprot id: G4RLU3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

768679:TTX RS10125
gene id: 768679:TTX_RS10125
uniprot id: G4RMM9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

768679:TTX RS02070
gene id: 768679:TTX_RS02070
uniprot id: G4RNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

768679:TTX RS08800
gene id: 768679:TTX_RS08800
uniprot id: G4RLJ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

768679:TTX RS02535
gene id: 768679:TTX_RS02535
uniprot id: G4RNP1
names: Similarity
messages: Belongs to the eIF-2-alpha family.

768679:TTX RS02255
gene id: 768679:TTX_RS02255
uniprot id: G4RNH9
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

768679:TTX RS02655
gene id: 768679:TTX_RS02655
uniprot id: G4RNR7
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

768679:TTX RS02335
gene id: 768679:TTX_RS02335
uniprot id: G4RNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

768679:TTX RS02375
gene id: 768679:TTX_RS02375
uniprot id: G4RNK7
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS09230
gene id: 768679:TTX_RS09230
uniprot id: G4RLT3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08215
gene id: 768679:TTX_RS08215
uniprot id: G4RL81
names: Similarity
messages: Belongs to the peptidase M24B family.

768679:TTX RS02835
gene id: 768679:TTX_RS02835
uniprot id: G4RNV3
names: Similarity
messages: Belongs to the PDCD5 family.

768679:TTX RS06995
gene id: 768679:TTX_RS06995
uniprot id: G4RKJ5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

768679:TTX RS09605
gene id: 768679:TTX_RS09605
uniprot id: G4RM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

768679:TTX RS04410
gene id: 768679:TTX_RS04410
uniprot id: G4RPS2
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04390
gene id: 768679:TTX_RS04390
uniprot id: G4RPR8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

768679:TTX RS05980
gene id: 768679:TTX_RS05980
uniprot id: G4RJY9
names: Function
names: Induction
names: Similarity
messages: Belongs to the CRISPR-associated Csa3 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). A putative DNA-binding protein it may regulate either or both of the Cas protein operons encoded on either side of it.
messages: Not significantly induced by ultraviolet light or by NaCl. A monocistronic operon.

768679:TTX RS00420
gene id: 768679:TTX_RS00420
uniprot id: G4RMC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

768679:TTX RS07860
gene id: 768679:TTX_RS07860
uniprot id: G4RL08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

768679:TTX RS04280
gene id: 768679:TTX_RS04280
uniprot id: G4RPP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

768679:TTX RS06145
gene id: 768679:TTX_RS06145
uniprot id: G4RK24
names: Similarity
messages: Belongs to the P(II) protein family.

768679:TTX RS04985
gene id: 768679:TTX_RS04985
uniprot id: G4RQ33
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04575
gene id: 768679:TTX_RS04575
uniprot id: G4RPV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS08270
gene id: 768679:TTX_RS08270
uniprot id: G4RL90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

768679:TTX RS00055
gene id: 768679:TTX_RS00055
uniprot id: G4RQ51
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

768679:TTX RS02310
gene id: 768679:TTX_RS02310
uniprot id: G4RNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

768679:TTX RS05595
gene id: 768679:TTX_RS05595
uniprot id: G4RJQ6
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

768679:TTX RS03715
gene id: 768679:TTX_RS03715
uniprot id: G4RPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

768679:TTX RS02515
gene id: 768679:TTX_RS02515
uniprot id: G4RNN6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

768679:TTX RS01945
gene id: 768679:TTX_RS01945
uniprot id: G4RNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

768679:TTX RS03710
gene id: 768679:TTX_RS03710
uniprot id: G4RPD1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

768679:TTX RS10025
gene id: 768679:TTX_RS10025
uniprot id: G4RM90
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS01475
gene id: 768679:TTX_RS01475
uniprot id: G4RN23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08590
gene id: 768679:TTX_RS08590
uniprot id: G4RLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS07910
gene id: 768679:TTX_RS07910
uniprot id: G4RL18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

768679:TTX RS08585
gene id: 768679:TTX_RS08585
uniprot id: G4RLF2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

768679:TTX RS08745
gene id: 768679:TTX_RS08745
uniprot id: G4RLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

768679:TTX RS05285
gene id: 768679:TTX_RS05285
uniprot id: G4RJJ3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

768679:TTX RS08550
gene id: 768679:TTX_RS08550
uniprot id: G4RLE5
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS02435
gene id: 768679:TTX_RS02435
uniprot id: G4RNL9
names: Similarity
messages: Belongs to the citrate synthase family.

768679:TTX RS08845
gene id: 768679:TTX_RS08845
uniprot id: G4RLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

768679:TTX RS05245
gene id: 768679:TTX_RS05245
uniprot id: G4RJI5
names: Similarity
messages: Belongs to the diphthine synthase family.

768679:TTX RS10075
gene id: 768679:TTX_RS10075
uniprot id: G4RML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

768679:TTX RS06320
gene id: 768679:TTX_RS06320
uniprot id: G4RK62
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00505
gene id: 768679:TTX_RS00505
uniprot id: G4RME3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

768679:TTX RS08520
gene id: 768679:TTX_RS08520
uniprot id: G4RLD9
names: Similarity
messages: Belongs to the class-I fumarase family.

768679:TTX RS09210
gene id: 768679:TTX_RS09210
uniprot id: G4RLS9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

768679:TTX RS01800
gene id: 768679:TTX_RS01800
uniprot id: G4RN88
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS05280
gene id: 768679:TTX_RS05280
uniprot id: G4RJJ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

768679:TTX RS04605
gene id: 768679:TTX_RS04605
uniprot id: G4RPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

768679:TTX RS04085
gene id: 768679:TTX_RS04085
uniprot id: G4RPK7
names: Similarity
messages: Belongs to the UPF0282 family.

768679:TTX RS00860
gene id: 768679:TTX_RS00860
uniprot id: G4RML5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

768679:TTX RS09065
gene id: 768679:TTX_RS09065
uniprot id: G4RLP8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

768679:TTX RS01095
gene id: 768679:TTX_RS01095
uniprot id: G4RMU8
names: Similarity
messages: Belongs to the complex I subunit 3 family.

768679:TTX RS02600
gene id: 768679:TTX_RS02600
uniprot id: G4RNQ4
names: Subcellular Location Annotation
messages: Nucleus

768679:TTX RS05330
gene id: 768679:TTX_RS05330
uniprot id: G4RJK2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

768679:TTX RS08970
gene id: 768679:TTX_RS08970
uniprot id: G4RLN0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

768679:TTX RS07410
gene id: 768679:TTX_RS07410
uniprot id: G4RKS4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

768679:TTX RS03735
gene id: 768679:TTX_RS03735
uniprot id: G4RPD7
names: Similarity
messages: Belongs to the thymidylate kinase family.

768679:TTX RS08870
gene id: 768679:TTX_RS08870
uniprot id: G4RLL0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

768679:TTX RS07680
gene id: 768679:TTX_RS07680
uniprot id: G4RKX6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

768679:TTX RS06755
gene id: 768679:TTX_RS06755
uniprot id: G4RKE7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

768679:TTX RS09785
gene id: 768679:TTX_RS09785
uniprot id: G4RM42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS09100
gene id: 768679:TTX_RS09100
uniprot id: G4RLQ5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

768679:TTX RS03795
gene id: 768679:TTX_RS03795
uniprot id: G4RPF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS09670
gene id: 768679:TTX_RS09670
uniprot id: G4RM20
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

768679:TTX RS06155
gene id: 768679:TTX_RS06155
uniprot id: G4RK26
names: Similarity
messages: Belongs to the HerA family.

768679:TTX RS00925
gene id: 768679:TTX_RS00925
uniprot id: G4RMR5
names: Similarity
messages: Belongs to the UPF0173 family.

768679:TTX RS09960
gene id: 768679:TTX_RS09960
uniprot id: G4RM76
names: Similarity
messages: Belongs to the phosphohexose mutase family.

768679:TTX RS02980
gene id: 768679:TTX_RS02980
uniprot id: G4RNY3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

768679:TTX RS07495
gene id: 768679:TTX_RS07495
uniprot id: G4RKU2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

768679:TTX RS08615
gene id: 768679:TTX_RS08615
uniprot id: G4RLF9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

768679:TTX RS08750
gene id: 768679:TTX_RS08750
uniprot id: G4RLI7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

768679:TTX RS06845
gene id: 768679:TTX_RS06845
uniprot id: G4RKG5
names: Similarity
messages: Belongs to the glutaredoxin family.

768679:TTX RS08725
gene id: 768679:TTX_RS08725
uniprot id: G4RLI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

768679:TTX RS02830
gene id: 768679:TTX_RS02830
uniprot id: G4RNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS08755
gene id: 768679:TTX_RS08755
uniprot id: G4RLI8
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

768679:TTX RS08775
gene id: 768679:TTX_RS08775
uniprot id: G4RLJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS02425
gene id: 768679:TTX_RS02425
uniprot id: Q8NKN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

768679:TTX RS02500
gene id: 768679:TTX_RS02500
uniprot id: G4RNN3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

768679:TTX RS04400
gene id: 768679:TTX_RS04400
uniprot id: G4RPS0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS03245
gene id: 768679:TTX_RS03245
uniprot id: G4RP36
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

768679:TTX RS08490
gene id: 768679:TTX_RS08490
uniprot id: G4RLD3
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS02630
gene id: 768679:TTX_RS02630
uniprot id: G4RNR1
names: Similarity
messages: Belongs to the UPF0237 family.

768679:TTX RS08595
gene id: 768679:TTX_RS08595
uniprot id: G4RLF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS01675
gene id: 768679:TTX_RS01675
uniprot id: Q703W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. To a lesser extent, is also active with xylose as substrate, but mannose, arabinose, galactose, fructose 6-phosphate, glucose 6-phosphate, glycerinaldehyde 3-phosphate, ribose, sorbitol, ethanol, erythritol, or lactose are not oxidized by the enzyme. Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+). Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
messages: Homodimer.

768679:TTX RS04395
gene id: 768679:TTX_RS04395
uniprot id: G4RPR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

768679:TTX RS03910
gene id: 768679:TTX_RS03910
uniprot id: G4RPH4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

768679:TTX RS02240
gene id: 768679:TTX_RS02240
uniprot id: G4RNH6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

768679:TTX RS06150
gene id: 768679:TTX_RS06150
uniprot id: G4RK25
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS08465
gene id: 768679:TTX_RS08465
uniprot id: G4RLC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS06720
gene id: 768679:TTX_RS06720
uniprot id: G4RKE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

768679:TTX RS00390
gene id: 768679:TTX_RS00390
uniprot id: G4RMC0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

768679:TTX RS09025
gene id: 768679:TTX_RS09025
uniprot id: G4RLP1
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

768679:TTX RS02030
gene id: 768679:TTX_RS02030
uniprot id: G4RND4
names: Similarity
messages: Belongs to the acylphosphatase family.

768679:TTX RS06375
gene id: 768679:TTX_RS06375
uniprot id: G4RK75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

768679:TTX RS00665
gene id: 768679:TTX_RS00665
uniprot id: G4RMH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

768679:TTX RS10065
gene id: 768679:TTX_RS10065
uniprot id: G4RML7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

768679:TTX RS09995
gene id: 768679:TTX_RS09995
uniprot id: G4RM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

768679:TTX RS09855
gene id: 768679:TTX_RS09855
uniprot id: G4RM55
names: Similarity
messages: Belongs to the AOR/FOR family.

768679:TTX RS07990
gene id: 768679:TTX_RS07990
uniprot id: G4RL34
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

768679:TTX RS00610
gene id: 768679:TTX_RS00610
uniprot id: G4RMG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

768679:TTX RS09465
gene id: 768679:TTX_RS09465
uniprot id: G4RLY1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

768679:TTX RS09685
gene id: 768679:TTX_RS09685
uniprot id: G4RM23
names: Similarity
messages: Belongs to the thioesterase PaaI family.

768679:TTX RS01460
gene id: 768679:TTX_RS01460
uniprot id: G4RN20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

768679:TTX RS00870
gene id: 768679:TTX_RS00870
uniprot id: G4RMQ4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

768679:TTX RS04480
gene id: 768679:TTX_RS04480
uniprot id: G4RPT7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

768679:TTX RS07950
gene id: 768679:TTX_RS07950
uniprot id: G4RL26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS05960
gene id: 768679:TTX_RS05960
uniprot id: G4RJY5
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: Binds 1 [4Fe-4S] cluster per subunit. It may be important for protein stability, since mutation of the Cys that bind the cofactor leads to a colorless, insoluble protein.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This may be a 5' to 3' ssDNA exonuclease (By similarity).
messages: Can form a Cascis complex with Cas1/2 and Csa1.
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity. Can also utilise Cu(2+).
messages: Slightly induced by 20 J/m2 ultraviolet light. Member of the csa1-cas1/2-cas4 operon.

768679:TTX RS01970
gene id: 768679:TTX_RS01970
uniprot id: G4RNC0
names: Similarity
messages: Belongs to the leucine-binding protein family.

768679:TTX RS04105
gene id: 768679:TTX_RS04105
uniprot id: G4RPL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

768679:TTX RS05115
gene id: 768679:TTX_RS05115
uniprot id: G4RJG0
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02970
gene id: 768679:TTX_RS02970
uniprot id: G4RNY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

768679:TTX RS10120
gene id: 768679:TTX_RS10120
uniprot id: G4RMM8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

768679:TTX RS04585
gene id: 768679:TTX_RS04585
uniprot id: G4RPV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS06065
gene id: 768679:TTX_RS06065
uniprot id: G4RK08
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

768679:TTX RS08080
gene id: 768679:TTX_RS08080
uniprot id: G4RL53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

768679:TTX RS06110
gene id: 768679:TTX_RS06110
uniprot id: P58315
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by citrate.
messages: Belongs to the DeoC/FbaB aldolase family.
messages: Catalyzes the reversible cleavage of fructose 1,6-bisphosphate (FBP) to glyceraldehyde 3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
messages: Cytoplasm
messages: Homodecamer (dimer of pentamers).

768679:TTX RS07365
gene id: 768679:TTX_RS07365
uniprot id: G4RKR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

768679:TTX RS01070
gene id: 768679:TTX_RS01070
uniprot id: G4RMU3
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

768679:TTX RS08050
gene id: 768679:TTX_RS08050
uniprot id: G4RL47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

768679:TTX RS09510
gene id: 768679:TTX_RS09510
uniprot id: G4RLZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

768679:TTX RS09720
gene id: 768679:TTX_RS09720
uniprot id: G4RM30
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

768679:TTX RS08105
gene id: 768679:TTX_RS08105
uniprot id: G4RL58
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

768679:TTX RS03700
gene id: 768679:TTX_RS03700
uniprot id: G4RPC9
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02945
gene id: 768679:TTX_RS02945
uniprot id: G4RNX6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

768679:TTX RS08085
gene id: 768679:TTX_RS08085
uniprot id: G4RL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

768679:TTX RS08620
gene id: 768679:TTX_RS08620
uniprot id: G4RLG0
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS07985
gene id: 768679:TTX_RS07985
uniprot id: G4RL33
names: Similarity
messages: Belongs to the UPF0111 family.

768679:TTX RS08255
gene id: 768679:TTX_RS08255
uniprot id: G4RL88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

768679:TTX RS09590
gene id: 768679:TTX_RS09590
uniprot id: G4RM04
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

768679:TTX RS03590
gene id: 768679:TTX_RS03590
uniprot id: G4RPA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

768679:TTX RS00485
gene id: 768679:TTX_RS00485
uniprot id: G4RMD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

768679:TTX RS03740
gene id: 768679:TTX_RS03740
uniprot id: G4RPD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

768679:TTX RS03985
gene id: 768679:TTX_RS03985
uniprot id: G4RPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

768679:TTX RS00220
gene id: 768679:TTX_RS00220
uniprot id: G4RQ82
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08715
gene id: 768679:TTX_RS08715
uniprot id: G4RLI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

768679:TTX RS01485
gene id: 768679:TTX_RS01485
uniprot id: G4RN25
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

768679:TTX RS09925
gene id: 768679:TTX_RS09925
uniprot id: G4RM69
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

768679:TTX RS09175
gene id: 768679:TTX_RS09175
uniprot id: G4RLS0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

768679:TTX RS09525
gene id: 768679:TTX_RS09525
uniprot id: G4RLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS04130
gene id: 768679:TTX_RS04130
uniprot id: G4RPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS01015
gene id: 768679:TTX_RS01015
uniprot id: G4RMT2
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00900
gene id: 768679:TTX_RS00900
uniprot id: G4RMR0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

768679:TTX RS09250
gene id: 768679:TTX_RS09250
uniprot id: G4RLT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

768679:TTX RS08890
gene id: 768679:TTX_RS08890
uniprot id: G4RLL4
names: Similarity
messages: Belongs to the TrpC family.

768679:TTX RS09980
gene id: 768679:TTX_RS09980
uniprot id: G4RM80
names: Similarity
messages: Belongs to the CutA family.

768679:TTX RS03340
gene id: 768679:TTX_RS03340
uniprot id: G4RP54
names: Subcellular Location Annotation
messages: Cell membrane

768679:TTX RS09195
gene id: 768679:TTX_RS09195
uniprot id: G4RLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS00940
gene id: 768679:TTX_RS00940
uniprot id: G4RMR8
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

768679:TTX RS08860
gene id: 768679:TTX_RS08860
uniprot id: G4RLK8
names: Similarity
messages: Belongs to the UPF0284 family.

768679:TTX RS06355
gene id: 768679:TTX_RS06355
uniprot id: G4RK71
names: Similarity
messages: Belongs to the archaeal ATPase family.

768679:TTX RS03705
gene id: 768679:TTX_RS03705
uniprot id: G4RPD0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

768679:TTX RS09185
gene id: 768679:TTX_RS09185
uniprot id: G4RLS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

768679:TTX RS07205
gene id: 768679:TTX_RS07205
uniprot id: G4RKN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

768679:TTX RS04425
gene id: 768679:TTX_RS04425
uniprot id: G4RPS5
names: Similarity
messages: Belongs to the DtxR/MntR family.

768679:TTX RS08540
gene id: 768679:TTX_RS08540
uniprot id: G4RLE3
names: Similarity
messages: Belongs to the AOR/FOR family.

768679:TTX RS08440
gene id: 768679:TTX_RS08440
uniprot id: G4RLC3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

768679:TTX RS03945
gene id: 768679:TTX_RS03945
uniprot id: G4RPI1
names: Function
messages: Probably involved in the biogenesis of the ribosome.

768679:TTX RS05215
gene id: 768679:TTX_RS05215
uniprot id: G4RJH9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

768679:TTX RS06010
gene id: 768679:TTX_RS06010
uniprot id: G4RJZ5
names: Function
names: Induction
names: Subunit
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
messages: Monomer (By similarity). Can form a Cascade complex with Csa5, Cas7, Cas5a, Cas3 and Cas3'.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS03510
gene id: 768679:TTX_RS03510
uniprot id: G4RP88
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

768679:TTX RS07440
gene id: 768679:TTX_RS07440
uniprot id: G4RKT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

768679:TTX RS02510
gene id: 768679:TTX_RS02510
uniprot id: G4RNN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

768679:TTX RS02415
gene id: 768679:TTX_RS02415
uniprot id: G4RNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

768679:TTX RS09645
gene id: 768679:TTX_RS09645
uniprot id: G4RM15
names: Similarity
messages: Belongs to the SUI1 family.

768679:TTX RS03760
gene id: 768679:TTX_RS03760
uniprot id: G4RPE3
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.

768679:TTX RS06850
gene id: 768679:TTX_RS06850
uniprot id: G4RKG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

768679:TTX RS07240
gene id: 768679:TTX_RS07240
uniprot id: G4RKP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

768679:TTX RS07110
gene id: 768679:TTX_RS07110
uniprot id: G4RKL5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

768679:TTX RS00945
gene id: 768679:TTX_RS00945
uniprot id: G4RMR9
names: Similarity
messages: Belongs to the HerA family.

768679:TTX RS06105
gene id: 768679:TTX_RS06105
uniprot id: G4RK16
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotrimer.
messages: Non-allosteric.

768679:TTX RS09255
gene id: 768679:TTX_RS09255
uniprot id: G4RLT8
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

768679:TTX RS04960
gene id: 768679:TTX_RS04960
uniprot id: G4RQ28
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

768679:TTX RS05185
gene id: 768679:TTX_RS05185
uniprot id: G4RJH3
names: Similarity
messages: Belongs to the acylphosphatase family.

768679:TTX RS08415
gene id: 768679:TTX_RS08415
uniprot id: G4RLB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

768679:TTX RS00385
gene id: 768679:TTX_RS00385
uniprot id: G4RMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

768679:TTX RS08560
gene id: 768679:TTX_RS08560
uniprot id: G4RLE7
names: Similarity
messages: Belongs to the Nth/MutY family.

768679:TTX RS09155
gene id: 768679:TTX_RS09155
uniprot id: G4RLR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

768679:TTX RS00620
gene id: 768679:TTX_RS00620
uniprot id: G4RMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.

768679:TTX RS04980
gene id: 768679:TTX_RS04980
uniprot id: G4RQ32
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

768679:TTX RS04830
gene id: 768679:TTX_RS04830
uniprot id: G4RQ04
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

768679:TTX RS01280
gene id: 768679:TTX_RS01280
uniprot id: G4RMY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

768679:TTX RS06690
gene id: 768679:TTX_RS06690
uniprot id: G4RKD4
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

768679:TTX RS04365
gene id: 768679:TTX_RS04365
uniprot id: G4RPR2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

768679:TTX RS06780
gene id: 768679:TTX_RS06780
uniprot id: G4RKF3
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

768679:TTX RS05415
gene id: 768679:TTX_RS05415
uniprot id: G4RJL9
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00565
gene id: 768679:TTX_RS00565
uniprot id: G4RMF5
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS09845
gene id: 768679:TTX_RS09845
uniprot id: G4RM53
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

768679:TTX RS03285
gene id: 768679:TTX_RS03285
uniprot id: G4RP44
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

768679:TTX RS03775
gene id: 768679:TTX_RS03775
uniprot id: G4RPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

768679:TTX RS05695
gene id: 768679:TTX_RS05695
uniprot id: G4RJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

768679:TTX RS05590
gene id: 768679:TTX_RS05590
uniprot id: G4RJQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

768679:TTX RS09450
gene id: 768679:TTX_RS09450
uniprot id: G4RLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

768679:TTX RS09390
gene id: 768679:TTX_RS09390
uniprot id: G4RLW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS02060
gene id: 768679:TTX_RS02060
uniprot id: G4RNE0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

768679:TTX RS00905
gene id: 768679:TTX_RS00905
uniprot id: G4RMR1
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

768679:TTX RS08295
gene id: 768679:TTX_RS08295
uniprot id: G4RL96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

768679:TTX RS01515
gene id: 768679:TTX_RS01515
uniprot id: G4RN30
names: Similarity
messages: Belongs to the peptidase U62 family.

768679:TTX RS02925
gene id: 768679:TTX_RS02925
uniprot id: G4RNX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

768679:TTX RS07695
gene id: 768679:TTX_RS07695
uniprot id: G4RKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

768679:TTX RS08900
gene id: 768679:TTX_RS08900
uniprot id: G4RLL6
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

768679:TTX RS06925
gene id: 768679:TTX_RS06925
uniprot id: G4RKI1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

768679:TTX RS02805
gene id: 768679:TTX_RS02805
uniprot id: G4RNU7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

768679:TTX RS04740
gene id: 768679:TTX_RS04740
uniprot id: G4RPY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

768679:TTX RS10195
gene id: 768679:TTX_RS10195
uniprot id: G4RMP4
names: Similarity
messages: Belongs to the MoaB/Mog family.

768679:TTX RS08955
gene id: 768679:TTX_RS08955
uniprot id: G4RLM7
names: Similarity
messages: Belongs to the UPF0215 family.

768679:TTX RS08060
gene id: 768679:TTX_RS08060
uniprot id: G4RL49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

768679:TTX RS07795
gene id: 768679:TTX_RS07795
uniprot id: G4RKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

768679:TTX RS08430
gene id: 768679:TTX_RS08430
uniprot id: G4RLC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

768679:TTX RS00990
gene id: 768679:TTX_RS00990
uniprot id: G4RMS7
names: Similarity
messages: Belongs to the HupF/HypC family.

768679:TTX RS01125
gene id: 768679:TTX_RS01125
uniprot id: G4RMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

768679:TTX RS01395
gene id: 768679:TTX_RS01395
uniprot id: G4RN07
names: Similarity
messages: Belongs to the glutaredoxin family.

768679:TTX RS08495
gene id: 768679:TTX_RS08495
uniprot id: G4RLD4
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS06070
gene id: 768679:TTX_RS06070
uniprot id: G4RK09
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

768679:TTX RS05050
gene id: 768679:TTX_RS05050
uniprot id: G4RJE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08095
gene id: 768679:TTX_RS08095
uniprot id: G4RL56
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

768679:TTX RS07265
gene id: 768679:TTX_RS07265
uniprot id: G4RKP5
names: Similarity
messages: Belongs to the RuvB family.

768679:TTX RS09385
gene id: 768679:TTX_RS09385
uniprot id: G4RLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

768679:TTX RS04695
gene id: 768679:TTX_RS04695
uniprot id: G4RPY0
names: Similarity
messages: Belongs to the peptidase M1 family.

768679:TTX RS08355
gene id: 768679:TTX_RS08355
uniprot id: G4RLA6
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

768679:TTX RS03475
gene id: 768679:TTX_RS03475
uniprot id: G4RP81
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS00465
gene id: 768679:TTX_RS00465
uniprot id: G4RMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

768679:TTX RS04950
gene id: 768679:TTX_RS04950
uniprot id: G4RQ26
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

768679:TTX RS05265
gene id: 768679:TTX_RS05265
uniprot id: G4RJI9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

768679:TTX RS04715
gene id: 768679:TTX_RS04715
uniprot id: G4RPY4
names: Similarity
messages: Belongs to the PGI/PMI family.

768679:TTX RS03920
gene id: 768679:TTX_RS03920
uniprot id: G4RPH6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

768679:TTX RS00540
gene id: 768679:TTX_RS00540
uniprot id: G4RMF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

768679:TTX RS08305
gene id: 768679:TTX_RS08305
uniprot id: G4RL98
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

768679:TTX RS03195
gene id: 768679:TTX_RS03195
uniprot id: G4RP27
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

768679:TTX RS02670
gene id: 768679:TTX_RS02670
uniprot id: G4RNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS08685
gene id: 768679:TTX_RS08685
uniprot id: G4RLH4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768679:TTX RS07355
gene id: 768679:TTX_RS07355
uniprot id: G4RKR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

768679:TTX RS03075
gene id: 768679:TTX_RS03075
uniprot id: G4RP02
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

768679:TTX RS05230
gene id: 768679:TTX_RS05230
uniprot id: G4RJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

768679:TTX RS04150
gene id: 768679:TTX_RS04150
uniprot id: G4RPL8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

768679:TTX RS05715
gene id: 768679:TTX_RS05715
uniprot id: G4RJT4
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02140
gene id: 768679:TTX_RS02140
uniprot id: G4RNF6
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04965
gene id: 768679:TTX_RS04965
uniprot id: G4RQ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

768679:TTX RS10060
gene id: 768679:TTX_RS10060
uniprot id: G4RM97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

768679:TTX RS05205
gene id: 768679:TTX_RS05205
uniprot id: G4RJH7
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS07455
gene id: 768679:TTX_RS07455
uniprot id: G4RKT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

768679:TTX RS00660
gene id: 768679:TTX_RS00660
uniprot id: G4RMH4
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

768679:TTX RS08360
gene id: 768679:TTX_RS08360
uniprot id: G4RLA7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

768679:TTX RS04070
gene id: 768679:TTX_RS04070
uniprot id: G4RPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

768679:TTX RS06660
gene id: 768679:TTX_RS06660
uniprot id: G4RKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

768679:TTX RS08045
gene id: 768679:TTX_RS08045
uniprot id: G4RL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

768679:TTX RS00700
gene id: 768679:TTX_RS00700
uniprot id: G4RMI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

768679:TTX RS06005
gene id: 768679:TTX_RS06005
uniprot id: G4RJZ4
names: Domain
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. Acts as a ssDNA and ssRNA nuclease, probably with both exo- and endonuclease activities. Activity is higher for DNA than RNA (By similarity).
messages: Monomer (By similarity). Can form a Cascade complex with Csa5, Cas7, Cas5a, Cas3 and Cas8a2.
messages: Proteins of this family have an N-terminal nuclease domain and a C-terminal helicase/ATPase domain. In some CRISPR/Cas systems the domains are swapped, in others they are encoded separately.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS09840
gene id: 768679:TTX_RS09840
uniprot id: G4RM52
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS03345
gene id: 768679:TTX_RS03345
uniprot id: G4RP55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

768679:TTX RS08740
gene id: 768679:TTX_RS08740
uniprot id: G4RLI5
names: Subcellular Location Annotation
messages: Cell membrane

768679:TTX RS03830
gene id: 768679:TTX_RS03830
uniprot id: G4RPF7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS00355
gene id: 768679:TTX_RS00355
uniprot id: G4RMB2
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

768679:TTX RS05740
gene id: 768679:TTX_RS05740
uniprot id: G4RJU0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

768679:TTX RS01390
gene id: 768679:TTX_RS01390
uniprot id: G4RN06
names: Similarity
messages: Belongs to the MCM family.

768679:TTX RS00080
gene id: 768679:TTX_RS00080
uniprot id: G4RQ55
names: Similarity
messages: Belongs to the RutC family.

768679:TTX RS01920
gene id: 768679:TTX_RS01920
uniprot id: G4RNB0
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00800
gene id: 768679:TTX_RS00800
uniprot id: G4RMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS00275
gene id: 768679:TTX_RS00275
uniprot id: G4RM98
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS03785
gene id: 768679:TTX_RS03785
uniprot id: G4RPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

768679:TTX RS08720
gene id: 768679:TTX_RS08720
uniprot id: G4RLI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

768679:TTX RS00885
gene id: 768679:TTX_RS00885
uniprot id: G4RMQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

768679:TTX RS08810
gene id: 768679:TTX_RS08810
uniprot id: G4RLJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

768679:TTX RS02285
gene id: 768679:TTX_RS02285
uniprot id: G4RNI5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

768679:TTX RS04155
gene id: 768679:TTX_RS04155
uniprot id: G4RPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

768679:TTX RS09500
gene id: 768679:TTX_RS09500
uniprot id: G4RLY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS04245
gene id: 768679:TTX_RS04245
uniprot id: G4RPN9
names: Similarity
messages: Belongs to the Nth/MutY family.

768679:TTX RS00850
gene id: 768679:TTX_RS00850
uniprot id: G4RML2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

768679:TTX RS01590
gene id: 768679:TTX_RS01590
uniprot id: G4RN43
names: Similarity
messages: Belongs to the BtpA family.

768679:TTX RS03175
gene id: 768679:TTX_RS03175
uniprot id: G4RP22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS03675
gene id: 768679:TTX_RS03675
uniprot id: G4RPC3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

768679:TTX RS08940
gene id: 768679:TTX_RS08940
uniprot id: G4RLM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

768679:TTX RS03610
gene id: 768679:TTX_RS03610
uniprot id: G4RPB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

768679:TTX RS04855
gene id: 768679:TTX_RS04855
uniprot id: G4RQ09
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

768679:TTX RS00985
gene id: 768679:TTX_RS00985
uniprot id: G4RMS6
names: Similarity
messages: Belongs to the HypD family.

768679:TTX RS10150
gene id: 768679:TTX_RS10150
uniprot id: G4RMN4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

768679:TTX RS04705
gene id: 768679:TTX_RS04705
uniprot id: G4RPY2
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS09170
gene id: 768679:TTX_RS09170
uniprot id: G4RLR9
names: Similarity
messages: Belongs to the MEMO1 family.

768679:TTX RS04370
gene id: 768679:TTX_RS04370
uniprot id: G4RPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS03020
gene id: 768679:TTX_RS03020
uniprot id: G4RNZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

768679:TTX RS01825
gene id: 768679:TTX_RS01825
uniprot id: G4RN93
names: Similarity
messages: Belongs to the UPF0047 family.

768679:TTX RS02570
gene id: 768679:TTX_RS02570
uniprot id: G4RNP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08480
gene id: 768679:TTX_RS08480
uniprot id: G4RLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

768679:TTX RS06645
gene id: 768679:TTX_RS06645
uniprot id: G4RKC5
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02605
gene id: 768679:TTX_RS02605
uniprot id: G4RNQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

768679:TTX RS04915
gene id: 768679:TTX_RS04915
uniprot id: G4RQ19
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

768679:TTX RS02840
gene id: 768679:TTX_RS02840
uniprot id: G4RNV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

768679:TTX RS07135
gene id: 768679:TTX_RS07135
uniprot id: G4RKM0
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

768679:TTX RS08020
gene id: 768679:TTX_RS08020
uniprot id: G4RL40
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

768679:TTX RS01520
gene id: 768679:TTX_RS01520
uniprot id: G4RN31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

768679:TTX RS05375
gene id: 768679:TTX_RS05375
uniprot id: G4RJL1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768679:TTX RS06835
gene id: 768679:TTX_RS06835
uniprot id: Q704B2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

768679:TTX RS05125
gene id: 768679:TTX_RS05125
uniprot id: G4RJG2
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS07190
gene id: 768679:TTX_RS07190
uniprot id: G4RKN1
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

768679:TTX RS01215
gene id: 768679:TTX_RS01215
uniprot id: G4RMX1
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

768679:TTX RS08250
gene id: 768679:TTX_RS08250
uniprot id: G4RL87
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

768679:TTX RS07485
gene id: 768679:TTX_RS07485
uniprot id: G4RKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

768679:TTX RS04820
gene id: 768679:TTX_RS04820
uniprot id: G4RQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

768679:TTX RS00915
gene id: 768679:TTX_RS00915
uniprot id: G4RMR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

768679:TTX RS03835
gene id: 768679:TTX_RS03835
uniprot id: G4RPF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

768679:TTX RS00245
gene id: 768679:TTX_RS00245
uniprot id: G4RQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

768679:TTX RS03925
gene id: 768679:TTX_RS03925
uniprot id: G4RPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

768679:TTX RS09275
gene id: 768679:TTX_RS09275
uniprot id: G4RLU4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

768679:TTX RS10050
gene id: 768679:TTX_RS10050
uniprot id: G4RM95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

768679:TTX RS09585
gene id: 768679:TTX_RS09585
uniprot id: G4RM03
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

768679:TTX RS07185
gene id: 768679:TTX_RS07185
uniprot id: G4RKN0
names: Similarity
messages: Belongs to the PrpD family.

768679:TTX RS09130
gene id: 768679:TTX_RS09130
uniprot id: G4RLR1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

768679:TTX RS08445
gene id: 768679:TTX_RS08445
uniprot id: G4RLC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS02960
gene id: 768679:TTX_RS02960
uniprot id: G4RNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

768679:TTX RS01105
gene id: 768679:TTX_RS01105
uniprot id: G4RMV0
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

768679:TTX RS04685
gene id: 768679:TTX_RS04685
uniprot id: G4RPX8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

768679:TTX RS03940
gene id: 768679:TTX_RS03940
uniprot id: G4RPI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS00405
gene id: 768679:TTX_RS00405
uniprot id: G4RMC3
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS05065
gene id: 768679:TTX_RS05065
uniprot id: G4RJF0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

768679:TTX RS07290
gene id: 768679:TTX_RS07290
uniprot id: G4RKQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

768679:TTX RS02265
gene id: 768679:TTX_RS02265
uniprot id: G4RNI1
names: Similarity
messages: Belongs to the peptidase S9C family.

768679:TTX RS01960
gene id: 768679:TTX_RS01960
uniprot id: G4RNB8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS09325
gene id: 768679:TTX_RS09325
uniprot id: G4RLV5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

768679:TTX RS07390
gene id: 768679:TTX_RS07390
uniprot id: G4RKS0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

768679:TTX RS09365
gene id: 768679:TTX_RS09365
uniprot id: G4RLW2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-63 and Arg-66) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

768679:TTX RS05190
gene id: 768679:TTX_RS05190
uniprot id: G4RJH4
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04550
gene id: 768679:TTX_RS04550
uniprot id: G4RPV1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

768679:TTX RS02815
gene id: 768679:TTX_RS02815
uniprot id: G4RNU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

768679:TTX RS03880
gene id: 768679:TTX_RS03880
uniprot id: G4RPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

768679:TTX RS00210
gene id: 768679:TTX_RS00210
uniprot id: G4RQ80
names: Similarity
messages: Belongs to the peptidase C56 family.

768679:TTX RS00280
gene id: 768679:TTX_RS00280
uniprot id: G4RM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS01340
gene id: 768679:TTX_RS01340
uniprot id: G4RMZ6
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

768679:TTX RS02825
gene id: 768679:TTX_RS02825
uniprot id: G4RNV1
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

768679:TTX RS01025
gene id: 768679:TTX_RS01025
uniprot id: G4RMT4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

768679:TTX RS07460
gene id: 768679:TTX_RS07460
uniprot id: G4RKT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS07975
gene id: 768679:TTX_RS07975
uniprot id: G4RL31
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

768679:TTX RS07445
gene id: 768679:TTX_RS07445
uniprot id: G4RKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

768679:TTX RS08070
gene id: 768679:TTX_RS08070
uniprot id: G4RL51
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

768679:TTX RS07345
gene id: 768679:TTX_RS07345
uniprot id: G4RKR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS00490
gene id: 768679:TTX_RS00490
uniprot id: G4RME0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

768679:TTX RS09835
gene id: 768679:TTX_RS09835
uniprot id: G4RM51
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS07300
gene id: 768679:TTX_RS07300
uniprot id: G4RKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

768679:TTX RS04500
gene id: 768679:TTX_RS04500
uniprot id: G4RPU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS06985
gene id: 768679:TTX_RS06985
uniprot id: G4RKJ3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

768679:TTX RS06630
gene id: 768679:TTX_RS06630
uniprot id: G4RKC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

768679:TTX RS08525
gene id: 768679:TTX_RS08525
uniprot id: G4RLE0
names: Similarity
messages: Belongs to the class-I fumarase family.

768679:TTX RS10100
gene id: 768679:TTX_RS10100
uniprot id: G4RMM4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

768679:TTX RS06195
gene id: 768679:TTX_RS06195
uniprot id: G4RK35
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

768679:TTX RS09260
gene id: 768679:TTX_RS09260
uniprot id: G4RLU0
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

768679:TTX RS02295
gene id: 768679:TTX_RS02295
uniprot id: G4RNI7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

768679:TTX RS02530
gene id: 768679:TTX_RS02530
uniprot id: G4RNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

768679:TTX RS06955
gene id: 768679:TTX_RS06955
uniprot id: G4RKI8
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

768679:TTX RS04405
gene id: 768679:TTX_RS04405
uniprot id: G4RPS1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

768679:TTX RS07210
gene id: 768679:TTX_RS07210
uniprot id: G4RKN5
names: Subcellular Location Annotation
messages: Cell membrane

768679:TTX RS05100
gene id: 768679:TTX_RS05100
uniprot id: G4RJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

768679:TTX RS00425
gene id: 768679:TTX_RS00425
uniprot id: G4RMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS02820
gene id: 768679:TTX_RS02820
uniprot id: G4RNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

768679:TTX RS08460
gene id: 768679:TTX_RS08460
uniprot id: G4RLC7
names: Similarity
messages: Belongs to the EPSP synthase family.

768679:TTX RS09425
gene id: 768679:TTX_RS09425
uniprot id: G4RLX3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

768679:TTX RS07385
gene id: 768679:TTX_RS07385
uniprot id: G4RKR9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS03765
gene id: 768679:TTX_RS03765
uniprot id: G4RPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

768679:TTX RS07840
gene id: 768679:TTX_RS07840
uniprot id: G4RL04
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

768679:TTX RS04440
gene id: 768679:TTX_RS04440
uniprot id: G4RPS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

768679:TTX RS03065
gene id: 768679:TTX_RS03065
uniprot id: G4RP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

768679:TTX RS02735
gene id: 768679:TTX_RS02735
uniprot id: G4RNT3
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00835
gene id: 768679:TTX_RS00835
uniprot id: G4RMK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

768679:TTX RS01775
gene id: 768679:TTX_RS01775
uniprot id: G4RN83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

768679:TTX RS00735
gene id: 768679:TTX_RS00735
uniprot id: G4RMI9
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS02025
gene id: 768679:TTX_RS02025
uniprot id: G4RND3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

768679:TTX RS07400
gene id: 768679:TTX_RS07400
uniprot id: G4RKS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

768679:TTX RS03780
gene id: 768679:TTX_RS03780
uniprot id: G4RPE7
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

768679:TTX RS02800
gene id: 768679:TTX_RS02800
uniprot id: G4RNU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS06210
gene id: 768679:TTX_RS06210
uniprot id: G4RK39
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

768679:TTX RS08945
gene id: 768679:TTX_RS08945
uniprot id: G4RLM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS07275
gene id: 768679:TTX_RS07275
uniprot id: G4RKP7
names: Similarity
messages: Belongs to the citrate synthase family.

768679:TTX RS09610
gene id: 768679:TTX_RS09610
uniprot id: G4RM08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

768679:TTX RS03755
gene id: 768679:TTX_RS03755
uniprot id: G4RPE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

768679:TTX RS03460
gene id: 768679:TTX_RS03460
uniprot id: G4RP78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

768679:TTX RS02845
gene id: 768679:TTX_RS02845
uniprot id: G4RNV5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

768679:TTX RS07085
gene id: 768679:TTX_RS07085
uniprot id: G4RKL0
names: Similarity
messages: Belongs to the UPF0201 family.

768679:TTX RS09755
gene id: 768679:TTX_RS09755
uniprot id: G4RM37
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

768679:TTX RS00070
gene id: 768679:TTX_RS00070
uniprot id: G4RQ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

768679:TTX RS09635
gene id: 768679:TTX_RS09635
uniprot id: G4RM13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

768679:TTX RS00685
gene id: 768679:TTX_RS00685
uniprot id: G4RMH9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

768679:TTX RS07075
gene id: 768679:TTX_RS07075
uniprot id: G4RKK8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

768679:TTX RS04875
gene id: 768679:TTX_RS04875
uniprot id: G4RQ13
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

768679:TTX RS00175
gene id: 768679:TTX_RS00175
uniprot id: G4RQ73
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

768679:TTX RS01480
gene id: 768679:TTX_RS01480
uniprot id: G4RN24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

768679:TTX RS08030
gene id: 768679:TTX_RS08030
uniprot id: G4RL42
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

768679:TTX RS08410
gene id: 768679:TTX_RS08410
uniprot id: G4RLB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS05995
gene id: 768679:TTX_RS05995
uniprot id: G4RJZ2
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-A/Apern subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
messages: Can form a Cascade complex with Csa5, Cas7, Cas3, Cas3' and Cas8a2.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS05920
gene id: 768679:TTX_RS05920
uniprot id: G4RJX6
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

768679:TTX RS04935
gene id: 768679:TTX_RS04935
uniprot id: G4RQ23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768679:TTX RS07515
gene id: 768679:TTX_RS07515
uniprot id: G4RKU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

768679:TTX RS03935
gene id: 768679:TTX_RS03935
uniprot id: G4RPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

768679:TTX RS05035
gene id: 768679:TTX_RS05035
uniprot id: G4RJE4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

768679:TTX RS03670
gene id: 768679:TTX_RS03670
uniprot id: G4RPC2
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS05060
gene id: 768679:TTX_RS05060
uniprot id: G4RJE9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

768679:TTX RS05985
gene id: 768679:TTX_RS05985
uniprot id: G4RJZ0
names: Function
names: Induction
names: Subunit
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
messages: Can form a Cascade complex with Cas7, Cas5a, Cas3, Cas3' and Cas8a2.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS03485
gene id: 768679:TTX_RS03485
uniprot id: G4RP83
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

768679:TTX RS07130
gene id: 768679:TTX_RS07130
uniprot id: G4RKL9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

768679:TTX RS07995
gene id: 768679:TTX_RS07995
uniprot id: G4RL35
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

768679:TTX RS06775
gene id: 768679:TTX_RS06775
uniprot id: G4RKF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS02345
gene id: 768679:TTX_RS02345
uniprot id: G4RNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

768679:TTX RS07625
gene id: 768679:TTX_RS07625
uniprot id: G4RKW5
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

768679:TTX RS08275
gene id: 768679:TTX_RS08275
uniprot id: G4RL91
names: Subcellular Location Annotation
messages: Nucleus

768679:TTX RS06000
gene id: 768679:TTX_RS06000
uniprot id: G4RJZ3
names: Domain
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated helicase Cas3 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. Probably unwinds dsDNA templates, thus providing substrates for CRISPR-associated endonuclease Cas3-HD. Unwinding is strongly increased in the presence of ATP, implying the helicase uses ATP to unwind substrate (By similarity).
messages: Can form a Cascade complex with Csa5, Cas7, Cas5a, Cas3' and Cas8a2.
messages: Proteins of this family have an N-terminal nuclease domain and a C-terminal helicase/ATPase domain. In some CRISPR/Cas systems the domains are swapped, in others they are encoded separately.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS04195
gene id: 768679:TTX_RS04195
uniprot id: G4RPM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

768679:TTX RS09975
gene id: 768679:TTX_RS09975
uniprot id: G4RM79
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

768679:TTX RS06685
gene id: 768679:TTX_RS06685
uniprot id: G4RKD3
names: Similarity
messages: Belongs to the AOR/FOR family.

768679:TTX RS00805
gene id: 768679:TTX_RS00805
uniprot id: G4RMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768679:TTX RS07340
gene id: 768679:TTX_RS07340
uniprot id: G4RKR0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

768679:TTX RS09285
gene id: 768679:TTX_RS09285
uniprot id: G4RLU6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

768679:TTX RS06950
gene id: 768679:TTX_RS06950
uniprot id: G4RKI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

768679:TTX RS05460
gene id: 768679:TTX_RS05460
uniprot id: G4RJM8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS00745
gene id: 768679:TTX_RS00745
uniprot id: G4RMJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

768679:TTX RS08760
gene id: 768679:TTX_RS08760
uniprot id: G4RLI9
names: Similarity
messages: Belongs to the complex I subunit 3 family.

768679:TTX RS03010
gene id: 768679:TTX_RS03010
uniprot id: G4RNY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

768679:TTX RS09490
gene id: 768679:TTX_RS09490
uniprot id: G4RLY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS06190
gene id: 768679:TTX_RS06190
uniprot id: G4RK34
names: Similarity
messages: Belongs to the AOR/FOR family.

768679:TTX RS08770
gene id: 768679:TTX_RS08770
uniprot id: G4RLJ1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS04800
gene id: 768679:TTX_RS04800
uniprot id: G4RPZ8
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

768679:TTX RS00185
gene id: 768679:TTX_RS00185
uniprot id: G4RQ75
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

768679:TTX RS00075
gene id: 768679:TTX_RS00075
uniprot id: G4RQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

768679:TTX RS07670
gene id: 768679:TTX_RS07670
uniprot id: G4RKX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

768679:TTX RS07965
gene id: 768679:TTX_RS07965
uniprot id: G4RL29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS02475
gene id: 768679:TTX_RS02475
uniprot id: G4RNM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

768679:TTX RS07895
gene id: 768679:TTX_RS07895
uniprot id: G4RL15
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

768679:TTX RS08710
gene id: 768679:TTX_RS08710
uniprot id: G4RLH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS08925
gene id: 768679:TTX_RS08925
uniprot id: G4RLM1
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

768679:TTX RS07665
gene id: 768679:TTX_RS07665
uniprot id: G4RKX3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768679:TTX RS05430
gene id: 768679:TTX_RS05430
uniprot id: G4RJM2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

768679:TTX RS09730
gene id: 768679:TTX_RS09730
uniprot id: G4RM32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

768679:TTX RS07310
gene id: 768679:TTX_RS07310
uniprot id: G4RKQ4
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

768679:TTX RS03845
gene id: 768679:TTX_RS03845
uniprot id: G4RPG0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

768679:TTX RS01100
gene id: 768679:TTX_RS01100
uniprot id: G4RMU9
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

768679:TTX RS08110
gene id: 768679:TTX_RS08110
uniprot id: G4RL59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

768679:TTX RS01785
gene id: 768679:TTX_RS01785
uniprot id: G4RN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

768679:TTX RS08100
gene id: 768679:TTX_RS08100
uniprot id: G4RL57
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

768679:TTX RS05990
gene id: 768679:TTX_RS05990
uniprot id: G4RJZ1
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated protein Cas7/Cst2/DevR family. Subtype I-a/Apern subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
messages: Can form a Cascade complex with Csa5, Cas5a, Cas3, Cas3' and Cas8a2.
messages: Repressed by 5 J/m2 ultraviolet light and 50 mM NaCl, slightly induced by 20 J/m2 ultraviolet light, 100 and 150 mM Nacl. Member of the csa5-cas7-cas5a-cas3-cas3'-cas8a2 operon.

768679:TTX RS03875
gene id: 768679:TTX_RS03875
uniprot id: G4RPG6
names: Similarity
messages: Belongs to the carbamate kinase family.

768679:TTX RS09315
gene id: 768679:TTX_RS09315
uniprot id: G4RLV3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768679:TTX RS09035
gene id: 768679:TTX_RS09035
uniprot id: G4RLP3
names: Similarity
messages: Belongs to the HypE family.

768679:TTX RS06035
gene id: 768679:TTX_RS06035
uniprot id: G4RK02
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

768679:TTX RS09090
gene id: 768679:TTX_RS09090
uniprot id: G4RLQ3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

768679:TTX RS03030
gene id: 768679:TTX_RS03030
uniprot id: G4RNZ3
names: Similarity
messages: Belongs to the glutamine synthetase family.

768679:TTX RS01695
gene id: 768679:TTX_RS01695
uniprot id: G4RN65
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

768679:TTX RS08000
gene id: 768679:TTX_RS08000
uniprot id: G4RL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

768679:TTX RS05030
gene id: 768679:TTX_RS05030
uniprot id: G4RJE3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

768679:TTX RS05370
gene id: 768679:TTX_RS05370
uniprot id: G4RJL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768679:TTX RS09795
gene id: 768679:TTX_RS09795
uniprot id: G4RM44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

768679:TTX RS03930
gene id: 768679:TTX_RS03930
uniprot id: G4RPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

768679:TTX RS02250
gene id: 768679:TTX_RS02250
uniprot id: G4RNH8
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

768679:TTX RS04850
gene id: 768679:TTX_RS04850
uniprot id: G4RQ08
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

768679:TTX RS04180
gene id: 768679:TTX_RS04180
uniprot id: G4RPM4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

768679:TTX RS00975
gene id: 768679:TTX_RS00975
uniprot id: G4RMS4
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS06230
gene id: 768679:TTX_RS06230
uniprot id: G4RK44
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Bifunctional enzyme which catalyzes the transfer of glucose from UDP-alpha-D-glucose to glucose-6-phosphate to form trehalose-6-phosphate (Tre6P) and removes the phosphate from Tre6P to produce free trehalose.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.
messages: May interact with the putative glycosyltransferase (GT) TTX_1305. TTX_1305 is required for the trehalose-6-phosphate synthase activity of tpsp.
messages: Part of an operon with putative glycosyltransferase TTX_1305 and putative membrane protein TTX_1304.1.

768679:TTX RS08510
gene id: 768679:TTX_RS08510
uniprot id: G4RLD7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

768679:TTX RS01965
gene id: 768679:TTX_RS01965
uniprot id: G4RNB9
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS04510
gene id: 768679:TTX_RS04510
uniprot id: G4RPU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

768679:TTX RS02550
gene id: 768679:TTX_RS02550
uniprot id: G4RNP4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

768679:TTX RS07765
gene id: 768679:TTX_RS07765
uniprot id: G4RKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

768679:TTX RS03170
gene id: 768679:TTX_RS03170
uniprot id: G4RP21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

768679:TTX RS08875
gene id: 768679:TTX_RS08875
uniprot id: G4RLL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

768679:TTX RS04910
gene id: 768679:TTX_RS04910
uniprot id: G4RQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

768679:TTX RS01505
gene id: 768679:TTX_RS01505
uniprot id: G4RN28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

768679:TTX RS03450
gene id: 768679:TTX_RS03450
uniprot id: G4RP76
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

768679:TTX RS07480
gene id: 768679:TTX_RS07480
uniprot id: G4RKT9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

768679:TTX RS05225
gene id: 768679:TTX_RS05225
uniprot id: G4RJI1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

768679:TTX RS03035
gene id: 768679:TTX_RS03035
uniprot id: G4RNZ4
names: Similarity
messages: Belongs to the glutamate synthase family.

768679:TTX RS02710
gene id: 768679:TTX_RS02710
uniprot id: G4RNS8
names: Subcellular Location Annotation
messages: Membrane

768679:TTX RS09280
gene id: 768679:TTX_RS09280
uniprot id: G4RLU5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

768679:TTX RS08065
gene id: 768679:TTX_RS08065
uniprot id: G4RL50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

768679:TTX RS03955
gene id: 768679:TTX_RS03955
uniprot id: G4RPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

768679:TTX RS08975
gene id: 768679:TTX_RS08975
uniprot id: G4RLN2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

768679:TTX RS08805
gene id: 768679:TTX_RS08805
uniprot id: G4RLJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

768679:TTX RS08055
gene id: 768679:TTX_RS08055
uniprot id: G4RL48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

768679:TTX RS07330
gene id: 768679:TTX_RS07330
uniprot id: G4RKQ8
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.