765911:THIVI RS03885
gene id: 765911:THIVI_RS03885
uniprot id: I3Y772
names: Caution
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS14080
gene id: 765911:THIVI_RS14080
uniprot id: I3YCT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

765911:THIVI RS09480
gene id: 765911:THIVI_RS09480
uniprot id: I3YAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

765911:THIVI RS09715
gene id: 765911:THIVI_RS09715
uniprot id: I3YAF3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

765911:THIVI RS04470
gene id: 765911:THIVI_RS04470
uniprot id: I3Y7I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

765911:THIVI RS04765
gene id: 765911:THIVI_RS04765
uniprot id: I3Y7P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

765911:THIVI RS09225
gene id: 765911:THIVI_RS09225
uniprot id: I3YA55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS07215
gene id: 765911:THIVI_RS07215
uniprot id: I3Y923
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS12745
gene id: 765911:THIVI_RS12745
uniprot id: I3YC44
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

765911:THIVI RS19380
gene id: 765911:THIVI_RS19380
uniprot id: I3YFS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

765911:THIVI RS00445
gene id: 765911:THIVI_RS00445
uniprot id: I3Y5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

765911:THIVI RS06740
gene id: 765911:THIVI_RS06740
uniprot id: I3Y8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

765911:THIVI RS14460
gene id: 765911:THIVI_RS14460
uniprot id: I3YD01
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

765911:THIVI RS19170
gene id: 765911:THIVI_RS19170
uniprot id: I3YFN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

765911:THIVI RS04710
gene id: 765911:THIVI_RS04710
uniprot id: I3Y7N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

765911:THIVI RS22115
gene id: 765911:THIVI_RS22115
uniprot id: I3YH99
names: Similarity
messages: Belongs to the ClpA/ClpB family.

765911:THIVI RS22060
gene id: 765911:THIVI_RS22060
uniprot id: I3YH89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS04530
gene id: 765911:THIVI_RS04530
uniprot id: I3Y7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

765911:THIVI RS00040
gene id: 765911:THIVI_RS00040
uniprot id: I3Y528
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

765911:THIVI RS09005
gene id: 765911:THIVI_RS09005
uniprot id: I3YA12
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS08540
gene id: 765911:THIVI_RS08540
uniprot id: I3Y9S1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

765911:THIVI RS05115
gene id: 765911:THIVI_RS05115
uniprot id: I3Y7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS15260
gene id: 765911:THIVI_RS15260
uniprot id: I3YDF8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

765911:THIVI RS12335
gene id: 765911:THIVI_RS12335
uniprot id: I3YBW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

765911:THIVI RS12735
gene id: 765911:THIVI_RS12735
uniprot id: I3YC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

765911:THIVI RS09065
gene id: 765911:THIVI_RS09065
uniprot id: I3YA22
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS15655
gene id: 765911:THIVI_RS15655
uniprot id: I3YDN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS04815
gene id: 765911:THIVI_RS04815
uniprot id: I3Y7Q5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

765911:THIVI RS13625
gene id: 765911:THIVI_RS13625
uniprot id: I3YCK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS16480
gene id: 765911:THIVI_RS16480
uniprot id: I3YE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS15430
gene id: 765911:THIVI_RS15430
uniprot id: I3YDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS04475
gene id: 765911:THIVI_RS04475
uniprot id: I3Y7I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

765911:THIVI RS14235
gene id: 765911:THIVI_RS14235
uniprot id: I3YCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

765911:THIVI RS06315
gene id: 765911:THIVI_RS06315
uniprot id: I3Y8K1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS05055
gene id: 765911:THIVI_RS05055
uniprot id: I3Y7U9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

765911:THIVI RS09720
gene id: 765911:THIVI_RS09720
uniprot id: I3YAF4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

765911:THIVI RS02590
gene id: 765911:THIVI_RS02590
uniprot id: I3Y6H5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

765911:THIVI RS11215
gene id: 765911:THIVI_RS11215
uniprot id: I3YB98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

765911:THIVI RS19865
gene id: 765911:THIVI_RS19865
uniprot id: I3YG13
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS12645
gene id: 765911:THIVI_RS12645
uniprot id: I3YC25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

765911:THIVI RS02660
gene id: 765911:THIVI_RS02660
uniprot id: I3Y6I8
names: Similarity
messages: Belongs to the DsrF/TusC family.

765911:THIVI RS18425
gene id: 765911:THIVI_RS18425
uniprot id: I3YF81
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS16070
gene id: 765911:THIVI_RS16070
uniprot id: I3YDX1
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS18950
gene id: 765911:THIVI_RS18950
uniprot id: I3YFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS12465
gene id: 765911:THIVI_RS12465
uniprot id: I3YBY7
names: Similarity
messages: Belongs to the thioredoxin family.

765911:THIVI RS00345
gene id: 765911:THIVI_RS00345
uniprot id: I3Y587
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

765911:THIVI RS20680
gene id: 765911:THIVI_RS20680
uniprot id: I3YGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

765911:THIVI RS17740
gene id: 765911:THIVI_RS17740
uniprot id: I3YEU4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

765911:THIVI RS02715
gene id: 765911:THIVI_RS02715
uniprot id: I3Y6J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

765911:THIVI RS17220
gene id: 765911:THIVI_RS17220
uniprot id: I3YEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

765911:THIVI RS08150
gene id: 765911:THIVI_RS08150
uniprot id: I3Y9J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

765911:THIVI RS13720
gene id: 765911:THIVI_RS13720
uniprot id: I3YCM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS13385
gene id: 765911:THIVI_RS13385
uniprot id: I3YCF4
names: Similarity
messages: Belongs to the Skp family.

765911:THIVI RS13235
gene id: 765911:THIVI_RS13235
uniprot id: I3YCC4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

765911:THIVI RS09660
gene id: 765911:THIVI_RS09660
uniprot id: U3GJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

765911:THIVI RS02530
gene id: 765911:THIVI_RS02530
uniprot id: I3Y6G3
names: Similarity
messages: Belongs to the citrate synthase family.

765911:THIVI RS18480
gene id: 765911:THIVI_RS18480
uniprot id: I3YF92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

765911:THIVI RS08700
gene id: 765911:THIVI_RS08700
uniprot id: I3Y9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

765911:THIVI RS15265
gene id: 765911:THIVI_RS15265
uniprot id: I3YDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

765911:THIVI RS18375
gene id: 765911:THIVI_RS18375
uniprot id: I3YF72
names: Similarity
messages: Belongs to the fructosamine kinase family.

765911:THIVI RS00410
gene id: 765911:THIVI_RS00410
uniprot id: I3Y5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

765911:THIVI RS18920
gene id: 765911:THIVI_RS18920
uniprot id: I3YFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS03485
gene id: 765911:THIVI_RS03485
uniprot id: I3Y701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

765911:THIVI RS16110
gene id: 765911:THIVI_RS16110
uniprot id: I3YDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

765911:THIVI RS13495
gene id: 765911:THIVI_RS13495
uniprot id: I3YCH6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

765911:THIVI RS12270
gene id: 765911:THIVI_RS12270
uniprot id: I3YBV0
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS04175
gene id: 765911:THIVI_RS04175
uniprot id: I3Y7C2
names: Similarity
messages: Belongs to the UPF0225 family.

765911:THIVI RS15715
gene id: 765911:THIVI_RS15715
uniprot id: I3YDP8
names: Similarity
messages: Belongs to the citrate synthase family.

765911:THIVI RS03555
gene id: 765911:THIVI_RS03555
uniprot id: I3Y714
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

765911:THIVI RS14375
gene id: 765911:THIVI_RS14375
uniprot id: I3YCY3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS06590
gene id: 765911:THIVI_RS06590
uniprot id: I3Y8P8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

765911:THIVI RS02315
gene id: 765911:THIVI_RS02315
uniprot id: I3Y6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

765911:THIVI RS16380
gene id: 765911:THIVI_RS16380
uniprot id: I3YE30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

765911:THIVI RS06485
gene id: 765911:THIVI_RS06485
uniprot id: I3Y8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765911:THIVI RS18975
gene id: 765911:THIVI_RS18975
uniprot id: I3YFJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

765911:THIVI RS16505
gene id: 765911:THIVI_RS16505
uniprot id: I3YE56
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

765911:THIVI RS16980
gene id: 765911:THIVI_RS16980
uniprot id: I3YEF0
names: Similarity
messages: Belongs to the Vsr family.

765911:THIVI RS15360
gene id: 765911:THIVI_RS15360
uniprot id: I3YDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

765911:THIVI RS01795
gene id: 765911:THIVI_RS01795
uniprot id: I3Y623
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

765911:THIVI RS20395
gene id: 765911:THIVI_RS20395
uniprot id: I3YGB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

765911:THIVI RS14940
gene id: 765911:THIVI_RS14940
uniprot id: I3YD93
names: Similarity
messages: Belongs to the HesB/IscA family.

765911:THIVI RS14065
gene id: 765911:THIVI_RS14065
uniprot id: I3YCT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS05335
gene id: 765911:THIVI_RS05335
uniprot id: I3Y809
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

765911:THIVI RS02435
gene id: 765911:THIVI_RS02435
uniprot id: I3Y6E6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS20490
gene id: 765911:THIVI_RS20490
uniprot id: I3YGD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

765911:THIVI RS08480
gene id: 765911:THIVI_RS08480
uniprot id: I3Y9Q9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

765911:THIVI RS20340
gene id: 765911:THIVI_RS20340
uniprot id: I3YGA4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

765911:THIVI RS03760
gene id: 765911:THIVI_RS03760
uniprot id: I3Y752
names: Similarity
messages: Belongs to the BolA/IbaG family.

765911:THIVI RS02255
gene id: 765911:THIVI_RS02255
uniprot id: I3Y6B0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

765911:THIVI RS22140
gene id: 765911:THIVI_RS22140
uniprot id: I3YHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

765911:THIVI RS17515
gene id: 765911:THIVI_RS17515
uniprot id: I3YEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS02325
gene id: 765911:THIVI_RS02325
uniprot id: I3Y6C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

765911:THIVI RS18145
gene id: 765911:THIVI_RS18145
uniprot id: I3YF28
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

765911:THIVI RS14875
gene id: 765911:THIVI_RS14875
uniprot id: I3YD80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

765911:THIVI RS05855
gene id: 765911:THIVI_RS05855
uniprot id: I3Y8A7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

765911:THIVI RS05940
gene id: 765911:THIVI_RS05940
uniprot id: I3Y8C3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

765911:THIVI RS08895
gene id: 765911:THIVI_RS08895
uniprot id: I3Y9Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

765911:THIVI RS13210
gene id: 765911:THIVI_RS13210
uniprot id: I3YCB9
names: Similarity
messages: Belongs to the UPF0758 family.

765911:THIVI RS08610
gene id: 765911:THIVI_RS08610
uniprot id: I3Y9T5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

765911:THIVI RS18955
gene id: 765911:THIVI_RS18955
uniprot id: I3YFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS12955
gene id: 765911:THIVI_RS12955
uniprot id: I3YC69
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

765911:THIVI RS08240
gene id: 765911:THIVI_RS08240
uniprot id: I3Y9L0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

765911:THIVI RS20485
gene id: 765911:THIVI_RS20485
uniprot id: I3YGD4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS02340
gene id: 765911:THIVI_RS02340
uniprot id: I3Y6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

765911:THIVI RS10025
gene id: 765911:THIVI_RS10025
uniprot id: I3YAL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS04950
gene id: 765911:THIVI_RS04950
uniprot id: I3Y7S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS03470
gene id: 765911:THIVI_RS03470
uniprot id: I3Y6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

765911:THIVI RS20290
gene id: 765911:THIVI_RS20290
uniprot id: I3YG82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

765911:THIVI RS16530
gene id: 765911:THIVI_RS16530
uniprot id: I3YE62
names: Similarity
messages: Belongs to the peptidase S24 family.

765911:THIVI RS04310
gene id: 765911:THIVI_RS04310
uniprot id: I3Y7F1
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

765911:THIVI RS11260
gene id: 765911:THIVI_RS11260
uniprot id: I3YBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

765911:THIVI RS10440
gene id: 765911:THIVI_RS10440
uniprot id: I3YAU2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

765911:THIVI RS04720
gene id: 765911:THIVI_RS04720
uniprot id: I3Y7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS17835
gene id: 765911:THIVI_RS17835
uniprot id: I3YEW2
names: Similarity
messages: Belongs to the asparagine synthetase family.

765911:THIVI RS01720
gene id: 765911:THIVI_RS01720
uniprot id: I3Y608
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

765911:THIVI RS04985
gene id: 765911:THIVI_RS04985
uniprot id: I3Y7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS19655
gene id: 765911:THIVI_RS19655
uniprot id: I3YFX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

765911:THIVI RS03100
gene id: 765911:THIVI_RS03100
uniprot id: I3Y6S2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

765911:THIVI RS14135
gene id: 765911:THIVI_RS14135
uniprot id: I3YCU8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS09495
gene id: 765911:THIVI_RS09495
uniprot id: I3YAA4
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18150
gene id: 765911:THIVI_RS18150
uniprot id: I3YF29
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

765911:THIVI RS05675
gene id: 765911:THIVI_RS05675
uniprot id: I3Y876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

765911:THIVI RS21570
gene id: 765911:THIVI_RS21570
uniprot id: I3YGZ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS09640
gene id: 765911:THIVI_RS09640
uniprot id: I3YAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS19795
gene id: 765911:THIVI_RS19795
uniprot id: I3YFZ9
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02575
gene id: 765911:THIVI_RS02575
uniprot id: I3Y6H2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS10845
gene id: 765911:THIVI_RS10845
uniprot id: I3YB24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

765911:THIVI RS21695
gene id: 765911:THIVI_RS21695
uniprot id: I3YH17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

765911:THIVI RS09525
gene id: 765911:THIVI_RS09525
uniprot id: I3YAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

765911:THIVI RS02470
gene id: 765911:THIVI_RS02470
uniprot id: I3Y6F2
names: Similarity
messages: Belongs to the YkuD family.

765911:THIVI RS05585
gene id: 765911:THIVI_RS05585
uniprot id: I3Y858
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

765911:THIVI RS19210
gene id: 765911:THIVI_RS19210
uniprot id: I3YFP2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

765911:THIVI RS10150
gene id: 765911:THIVI_RS10150
uniprot id: I3YAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

765911:THIVI RS20160
gene id: 765911:THIVI_RS20160
uniprot id: I3YG73
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

765911:THIVI RS03320
gene id: 765911:THIVI_RS03320
uniprot id: I3Y6W7
names: Similarity
messages: Belongs to the DEAD box helicase family.

765911:THIVI RS07915
gene id: 765911:THIVI_RS07915
uniprot id: I3Y9E9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

765911:THIVI RS04560
gene id: 765911:THIVI_RS04560
uniprot id: I3Y7K1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

765911:THIVI RS09215
gene id: 765911:THIVI_RS09215
uniprot id: I3YA53
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

765911:THIVI RS15795
gene id: 765911:THIVI_RS15795
uniprot id: I3YDR5
names: Similarity
messages: Belongs to the hemerythrin family.

765911:THIVI RS03335
gene id: 765911:THIVI_RS03335
uniprot id: I3Y6X0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

765911:THIVI RS14540
gene id: 765911:THIVI_RS14540
uniprot id: I3YD16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

765911:THIVI RS06685
gene id: 765911:THIVI_RS06685
uniprot id: I3Y8R7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS14590
gene id: 765911:THIVI_RS14590
uniprot id: I3YD26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

765911:THIVI RS11945
gene id: 765911:THIVI_RS11945
uniprot id: I3YBN8
names: Subcellular Location Annotation
messages: Cell inner membrane

765911:THIVI RS09620
gene id: 765911:THIVI_RS09620
uniprot id: I3YAD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

765911:THIVI RS21685
gene id: 765911:THIVI_RS21685
uniprot id: I3YH15
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

765911:THIVI RS20360
gene id: 765911:THIVI_RS20360
uniprot id: I3YGA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

765911:THIVI RS12490
gene id: 765911:THIVI_RS12490
uniprot id: I3YBZ3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS20365
gene id: 765911:THIVI_RS20365
uniprot id: I3YGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

765911:THIVI RS16840
gene id: 765911:THIVI_RS16840
uniprot id: I3YEC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

765911:THIVI RS13390
gene id: 765911:THIVI_RS13390
uniprot id: I3YCF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

765911:THIVI RS15460
gene id: 765911:THIVI_RS15460
uniprot id: I3YDJ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

765911:THIVI RS14595
gene id: 765911:THIVI_RS14595
uniprot id: I3YD27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS04360
gene id: 765911:THIVI_RS04360
uniprot id: I3Y7G1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

765911:THIVI RS04745
gene id: 765911:THIVI_RS04745
uniprot id: I3Y7P1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

765911:THIVI RS19675
gene id: 765911:THIVI_RS19675
uniprot id: I3YFX8
names: Subcellular Location Annotation
messages: Mitochondrion

765911:THIVI RS02950
gene id: 765911:THIVI_RS02950
uniprot id: I3Y6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

765911:THIVI RS09790
gene id: 765911:THIVI_RS09790
uniprot id: I3YAG8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

765911:THIVI RS02860
gene id: 765911:THIVI_RS02860
uniprot id: I3Y6M7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS03455
gene id: 765911:THIVI_RS03455
uniprot id: I3Y6Z5
names: Similarity
messages: Belongs to the NadC/ModD family.

765911:THIVI RS07540
gene id: 765911:THIVI_RS07540
uniprot id: I3Y982
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

765911:THIVI RS17445
gene id: 765911:THIVI_RS17445
uniprot id: I3YEP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

765911:THIVI RS03275
gene id: 765911:THIVI_RS03275
uniprot id: I3Y6V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

765911:THIVI RS16460
gene id: 765911:THIVI_RS16460
uniprot id: I3YE47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS12590
gene id: 765911:THIVI_RS12590
uniprot id: I3YC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

765911:THIVI RS14070
gene id: 765911:THIVI_RS14070
uniprot id: I3YCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

765911:THIVI RS08135
gene id: 765911:THIVI_RS08135
uniprot id: I3Y9I9
names: Similarity
messages: Belongs to the CobH/CbiC family.

765911:THIVI RS00195
gene id: 765911:THIVI_RS00195
uniprot id: I3Y559
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS08285
gene id: 765911:THIVI_RS08285
uniprot id: I3Y9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

765911:THIVI RS22165
gene id: 765911:THIVI_RS22165
uniprot id: I3YHB0
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS21105
gene id: 765911:THIVI_RS21105
uniprot id: I3YGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

765911:THIVI RS20060
gene id: 765911:THIVI_RS20060
uniprot id: I3YG52
names: Similarity
messages: Belongs to the RutC family.

765911:THIVI RS12255
gene id: 765911:THIVI_RS12255
uniprot id: I3YBU7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS13075
gene id: 765911:THIVI_RS13075
uniprot id: I3YC92
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

765911:THIVI RS08145
gene id: 765911:THIVI_RS08145
uniprot id: I3Y9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

765911:THIVI RS03535
gene id: 765911:THIVI_RS03535
uniprot id: I3Y710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

765911:THIVI RS22240
gene id: 765911:THIVI_RS22240
uniprot id: I3YHC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

765911:THIVI RS01845
gene id: 765911:THIVI_RS01845
uniprot id: I3Y633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

765911:THIVI RS02565
gene id: 765911:THIVI_RS02565
uniprot id: I3Y6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

765911:THIVI RS01145
gene id: 765911:THIVI_RS01145
uniprot id: I3Y5N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

765911:THIVI RS20920
gene id: 765911:THIVI_RS20920
uniprot id: I3YGM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

765911:THIVI RS13940
gene id: 765911:THIVI_RS13940
uniprot id: I3YCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS00465
gene id: 765911:THIVI_RS00465
uniprot id: I3Y5B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

765911:THIVI RS09300
gene id: 765911:THIVI_RS09300
uniprot id: I3YA62
names: Similarity
messages: Belongs to the peptidase S13 family.

765911:THIVI RS01910
gene id: 765911:THIVI_RS01910
uniprot id: I3Y644
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

765911:THIVI RS18435
gene id: 765911:THIVI_RS18435
uniprot id: I3YF83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

765911:THIVI RS14920
gene id: 765911:THIVI_RS14920
uniprot id: I3YD89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

765911:THIVI RS20305
gene id: 765911:THIVI_RS20305
uniprot id: I3YG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

765911:THIVI RS02375
gene id: 765911:THIVI_RS02375
uniprot id: I3Y6D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

765911:THIVI RS01450
gene id: 765911:THIVI_RS01450
uniprot id: I3Y5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

765911:THIVI RS13125
gene id: 765911:THIVI_RS13125
uniprot id: I3YCA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS08470
gene id: 765911:THIVI_RS08470
uniprot id: I3Y9Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

765911:THIVI RS14805
gene id: 765911:THIVI_RS14805
uniprot id: I3YD65
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

765911:THIVI RS17450
gene id: 765911:THIVI_RS17450
uniprot id: I3YEP2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

765911:THIVI RS08565
gene id: 765911:THIVI_RS08565
uniprot id: I3Y9S6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

765911:THIVI RS00375
gene id: 765911:THIVI_RS00375
uniprot id: I3Y593
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS09095
gene id: 765911:THIVI_RS09095
uniprot id: I3YA28
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

765911:THIVI RS09360
gene id: 765911:THIVI_RS09360
uniprot id: I3YA74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS11165
gene id: 765911:THIVI_RS11165
uniprot id: I3YB88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

765911:THIVI RS13355
gene id: 765911:THIVI_RS13355
uniprot id: I3YCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

765911:THIVI RS08300
gene id: 765911:THIVI_RS08300
uniprot id: I3Y9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

765911:THIVI RS22010
gene id: 765911:THIVI_RS22010
uniprot id: I3YH80
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

765911:THIVI RS11210
gene id: 765911:THIVI_RS11210
uniprot id: I3YB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

765911:THIVI RS11520
gene id: 765911:THIVI_RS11520
uniprot id: I3YBF7
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

765911:THIVI RS22575
gene id: 765911:THIVI_RS22575
uniprot id: I3Y8K9
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS01060
gene id: 765911:THIVI_RS01060
uniprot id: I3Y5M0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

765911:THIVI RS13270
gene id: 765911:THIVI_RS13270
uniprot id: I3YCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

765911:THIVI RS17810
gene id: 765911:THIVI_RS17810
uniprot id: U3GKG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

765911:THIVI RS15005
gene id: 765911:THIVI_RS15005
uniprot id: I3YDA6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

765911:THIVI RS10245
gene id: 765911:THIVI_RS10245
uniprot id: I3YAQ6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

765911:THIVI RS13565
gene id: 765911:THIVI_RS13565
uniprot id: I3YCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

765911:THIVI RS10420
gene id: 765911:THIVI_RS10420
uniprot id: I3YAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS06720
gene id: 765911:THIVI_RS06720
uniprot id: I3Y8S6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03260
gene id: 765911:THIVI_RS03260
uniprot id: I3Y6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

765911:THIVI RS08695
gene id: 765911:THIVI_RS08695
uniprot id: I3Y9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

765911:THIVI RS10275
gene id: 765911:THIVI_RS10275
uniprot id: I3YAR2
names: Similarity
messages: Belongs to the ArsC family.

765911:THIVI RS13085
gene id: 765911:THIVI_RS13085
uniprot id: I3YC94
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

765911:THIVI RS09655
gene id: 765911:THIVI_RS09655
uniprot id: U3GJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

765911:THIVI RS06910
gene id: 765911:THIVI_RS06910
uniprot id: I3Y8W6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

765911:THIVI RS04415
gene id: 765911:THIVI_RS04415
uniprot id: I3Y7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS06325
gene id: 765911:THIVI_RS06325
uniprot id: I3Y8K3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03200
gene id: 765911:THIVI_RS03200
uniprot id: I3Y6U2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS11615
gene id: 765911:THIVI_RS11615
uniprot id: I3YBH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS00490
gene id: 765911:THIVI_RS00490
uniprot id: I3Y5B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

765911:THIVI RS20890
gene id: 765911:THIVI_RS20890
uniprot id: I3YGL5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

765911:THIVI RS22050
gene id: 765911:THIVI_RS22050
uniprot id: I3YH87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

765911:THIVI RS10030
gene id: 765911:THIVI_RS10030
uniprot id: I3YAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

765911:THIVI RS22910
gene id: 765911:THIVI_RS22910
uniprot id: I3YDN1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

765911:THIVI RS15640
gene id: 765911:THIVI_RS15640
uniprot id: I3YDN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

765911:THIVI RS16820
gene id: 765911:THIVI_RS16820
uniprot id: I3YEB9
names: Similarity
messages: Belongs to the P(II) protein family.

765911:THIVI RS06585
gene id: 765911:THIVI_RS06585
uniprot id: I3Y8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

765911:THIVI RS03780
gene id: 765911:THIVI_RS03780
uniprot id: I3Y757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

765911:THIVI RS00035
gene id: 765911:THIVI_RS00035
uniprot id: I3Y527
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

765911:THIVI RS18225
gene id: 765911:THIVI_RS18225
uniprot id: I3YF42
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

765911:THIVI RS12615
gene id: 765911:THIVI_RS12615
uniprot id: I3YC19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

765911:THIVI RS12470
gene id: 765911:THIVI_RS12470
uniprot id: I3YBY9
names: Subcellular Location Annotation
messages: Cell inner membrane

765911:THIVI RS02505
gene id: 765911:THIVI_RS02505
uniprot id: I3Y6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

765911:THIVI RS15710
gene id: 765911:THIVI_RS15710
uniprot id: I3YDP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

765911:THIVI RS16200
gene id: 765911:THIVI_RS16200
uniprot id: I3YDZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS15120
gene id: 765911:THIVI_RS15120
uniprot id: I3YDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

765911:THIVI RS15890
gene id: 765911:THIVI_RS15890
uniprot id: I3YDT3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

765911:THIVI RS17435
gene id: 765911:THIVI_RS17435
uniprot id: I3YEN9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

765911:THIVI RS03625
gene id: 765911:THIVI_RS03625
uniprot id: I3Y727
names: Similarity
messages: Belongs to the aspartokinase family.

765911:THIVI RS18420
gene id: 765911:THIVI_RS18420
uniprot id: I3YF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

765911:THIVI RS16865
gene id: 765911:THIVI_RS16865
uniprot id: I3YEC8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

765911:THIVI RS18460
gene id: 765911:THIVI_RS18460
uniprot id: I3YF88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS11185
gene id: 765911:THIVI_RS11185
uniprot id: I3YB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

765911:THIVI RS15145
gene id: 765911:THIVI_RS15145
uniprot id: I3YDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

765911:THIVI RS19715
gene id: 765911:THIVI_RS19715
uniprot id: I3YFY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

765911:THIVI RS06660
gene id: 765911:THIVI_RS06660
uniprot id: I3Y8R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

765911:THIVI RS09650
gene id: 765911:THIVI_RS09650
uniprot id: U3GJZ3
names: Function
names: PTM
messages: Binds 4 heme groups per subunit.
messages: The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

765911:THIVI RS15765
gene id: 765911:THIVI_RS15765
uniprot id: I3YDQ8
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

765911:THIVI RS16340
gene id: 765911:THIVI_RS16340
uniprot id: I3YE22
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

765911:THIVI RS05480
gene id: 765911:THIVI_RS05480
uniprot id: I3Y837
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

765911:THIVI RS01935
gene id: 765911:THIVI_RS01935
uniprot id: I3Y650
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

765911:THIVI RS15635
gene id: 765911:THIVI_RS15635
uniprot id: I3YDN4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

765911:THIVI RS00365
gene id: 765911:THIVI_RS00365
uniprot id: I3Y591
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS00390
gene id: 765911:THIVI_RS00390
uniprot id: I3Y596
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS04605
gene id: 765911:THIVI_RS04605
uniprot id: I3Y7L0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

765911:THIVI RS18845
gene id: 765911:THIVI_RS18845
uniprot id: I3YFH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

765911:THIVI RS17915
gene id: 765911:THIVI_RS17915
uniprot id: I3YEX9
names: Similarity
messages: Belongs to the HupF/HypC family.

765911:THIVI RS00900
gene id: 765911:THIVI_RS00900
uniprot id: I3Y5I9
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS22075
gene id: 765911:THIVI_RS22075
uniprot id: I3YH92
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS09630
gene id: 765911:THIVI_RS09630
uniprot id: I3YAD3
names: Similarity
messages: Belongs to the UPF0047 family.

765911:THIVI RS13005
gene id: 765911:THIVI_RS13005
uniprot id: I3YC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS09350
gene id: 765911:THIVI_RS09350
uniprot id: I3YA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS12285
gene id: 765911:THIVI_RS12285
uniprot id: I3YBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

765911:THIVI RS14835
gene id: 765911:THIVI_RS14835
uniprot id: I3YD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

765911:THIVI RS04090
gene id: 765911:THIVI_RS04090
uniprot id: I3Y7A6
names: Similarity
messages: Belongs to the thioredoxin family.

765911:THIVI RS16660
gene id: 765911:THIVI_RS16660
uniprot id: I3YE87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

765911:THIVI RS12175
gene id: 765911:THIVI_RS12175
uniprot id: I3YBT1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS08465
gene id: 765911:THIVI_RS08465
uniprot id: I3Y9Q6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS10055
gene id: 765911:THIVI_RS10055
uniprot id: I3YAM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

765911:THIVI RS21990
gene id: 765911:THIVI_RS21990
uniprot id: I3YH76
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

765911:THIVI RS05485
gene id: 765911:THIVI_RS05485
uniprot id: I3Y838
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

765911:THIVI RS12300
gene id: 765911:THIVI_RS12300
uniprot id: I3YBV6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS09325
gene id: 765911:THIVI_RS09325
uniprot id: I3YA67
names: Similarity
messages: Belongs to the phosphoribulokinase family.

765911:THIVI RS07615
gene id: 765911:THIVI_RS07615
uniprot id: I3Y996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

765911:THIVI RS10095
gene id: 765911:THIVI_RS10095
uniprot id: I3YAM8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

765911:THIVI RS07580
gene id: 765911:THIVI_RS07580
uniprot id: I3Y989
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

765911:THIVI RS04800
gene id: 765911:THIVI_RS04800
uniprot id: I3Y7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

765911:THIVI RS19830
gene id: 765911:THIVI_RS19830
uniprot id: I3YG06
names: Similarity
messages: Belongs to the peptidase U62 family.

765911:THIVI RS18045
gene id: 765911:THIVI_RS18045
uniprot id: I3YF03
names: Similarity
messages: Belongs to the UPF0234 family.

765911:THIVI RS01965
gene id: 765911:THIVI_RS01965
uniprot id: I3Y656
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

765911:THIVI RS20385
gene id: 765911:THIVI_RS20385
uniprot id: I3YGB3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

765911:THIVI RS18415
gene id: 765911:THIVI_RS18415
uniprot id: I3YF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

765911:THIVI RS19420
gene id: 765911:THIVI_RS19420
uniprot id: I3YFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

765911:THIVI RS20915
gene id: 765911:THIVI_RS20915
uniprot id: I3YGL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS08495
gene id: 765911:THIVI_RS08495
uniprot id: I3Y9R2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765911:THIVI RS01725
gene id: 765911:THIVI_RS01725
uniprot id: I3Y609
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

765911:THIVI RS14430
gene id: 765911:THIVI_RS14430
uniprot id: I3YCZ4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

765911:THIVI RS04690
gene id: 765911:THIVI_RS04690
uniprot id: I3Y7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

765911:THIVI RS16255
gene id: 765911:THIVI_RS16255
uniprot id: I3YE05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

765911:THIVI RS03220
gene id: 765911:THIVI_RS03220
uniprot id: I3Y6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

765911:THIVI RS04420
gene id: 765911:THIVI_RS04420
uniprot id: I3Y7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765911:THIVI RS10425
gene id: 765911:THIVI_RS10425
uniprot id: I3YAT9
names: Similarity
messages: Belongs to the YjdM family.

765911:THIVI RS12115
gene id: 765911:THIVI_RS12115
uniprot id: I3YBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

765911:THIVI RS12560
gene id: 765911:THIVI_RS12560
uniprot id: I3YC08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

765911:THIVI RS09575
gene id: 765911:THIVI_RS09575
uniprot id: I3YAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS04460
gene id: 765911:THIVI_RS04460
uniprot id: I3Y7I1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

765911:THIVI RS22215
gene id: 765911:THIVI_RS22215
uniprot id: I3YHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

765911:THIVI RS15235
gene id: 765911:THIVI_RS15235
uniprot id: I3YDF3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS16320
gene id: 765911:THIVI_RS16320
uniprot id: I3YE18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

765911:THIVI RS19030
gene id: 765911:THIVI_RS19030
uniprot id: I3YFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

765911:THIVI RS20225
gene id: 765911:THIVI_RS20225
uniprot id: I3YG82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

765911:THIVI RS18300
gene id: 765911:THIVI_RS18300
uniprot id: I3YF57
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765911:THIVI RS04620
gene id: 765911:THIVI_RS04620
uniprot id: I3Y7L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

765911:THIVI RS20870
gene id: 765911:THIVI_RS20870
uniprot id: I3YGL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

765911:THIVI RS22200
gene id: 765911:THIVI_RS22200
uniprot id: I3YHB7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

765911:THIVI RS08675
gene id: 765911:THIVI_RS08675
uniprot id: I3Y9U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

765911:THIVI RS19065
gene id: 765911:THIVI_RS19065
uniprot id: I3YFL2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

765911:THIVI RS19350
gene id: 765911:THIVI_RS19350
uniprot id: I3YFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

765911:THIVI RS20415
gene id: 765911:THIVI_RS20415
uniprot id: I3YGC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

765911:THIVI RS01065
gene id: 765911:THIVI_RS01065
uniprot id: I3Y5M1
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

765911:THIVI RS13160
gene id: 765911:THIVI_RS13160
uniprot id: I3YCA9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

765911:THIVI RS03640
gene id: 765911:THIVI_RS03640
uniprot id: I3Y730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

765911:THIVI RS16030
gene id: 765911:THIVI_RS16030
uniprot id: I3YDW3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

765911:THIVI RS04615
gene id: 765911:THIVI_RS04615
uniprot id: I3Y7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

765911:THIVI RS06190
gene id: 765911:THIVI_RS06190
uniprot id: I3Y8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

765911:THIVI RS20420
gene id: 765911:THIVI_RS20420
uniprot id: I3YGC1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

765911:THIVI RS19320
gene id: 765911:THIVI_RS19320
uniprot id: I3YFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

765911:THIVI RS22380
gene id: 765911:THIVI_RS22380
uniprot id: I3Y537
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

765911:THIVI RS15350
gene id: 765911:THIVI_RS15350
uniprot id: I3YDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

765911:THIVI RS21010
gene id: 765911:THIVI_RS21010
uniprot id: I3YGN8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

765911:THIVI RS06210
gene id: 765911:THIVI_RS06210
uniprot id: I3Y8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

765911:THIVI RS05850
gene id: 765911:THIVI_RS05850
uniprot id: I3Y8A6
names: Similarity
messages: Belongs to the PhoH family.

765911:THIVI RS03765
gene id: 765911:THIVI_RS03765
uniprot id: I3Y754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS10720
gene id: 765911:THIVI_RS10720
uniprot id: I3YAZ9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

765911:THIVI RS02765
gene id: 765911:THIVI_RS02765
uniprot id: I3Y6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

765911:THIVI RS01930
gene id: 765911:THIVI_RS01930
uniprot id: I3Y649
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

765911:THIVI RS00105
gene id: 765911:THIVI_RS00105
uniprot id: I3Y541
names: Similarity
messages: Belongs to the fabD family.

765911:THIVI RS08375
gene id: 765911:THIVI_RS08375
uniprot id: I3Y9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

765911:THIVI RS10850
gene id: 765911:THIVI_RS10850
uniprot id: I3YB25
names: Similarity
messages: Belongs to the MipA/OmpV family.

765911:THIVI RS09675
gene id: 765911:THIVI_RS09675
uniprot id: I3YAE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

765911:THIVI RS05650
gene id: 765911:THIVI_RS05650
uniprot id: I3Y871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

765911:THIVI RS03435
gene id: 765911:THIVI_RS03435
uniprot id: I3Y6Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS21755
gene id: 765911:THIVI_RS21755
uniprot id: I3YH28
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

765911:THIVI RS20270
gene id: 765911:THIVI_RS20270
uniprot id: I3YG90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

765911:THIVI RS09540
gene id: 765911:THIVI_RS09540
uniprot id: I3YAB2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

765911:THIVI RS12145
gene id: 765911:THIVI_RS12145
uniprot id: I3YBS5
names: Similarity
messages: Belongs to the thioredoxin family.

765911:THIVI RS15605
gene id: 765911:THIVI_RS15605
uniprot id: I3YDM8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

765911:THIVI RS15325
gene id: 765911:THIVI_RS15325
uniprot id: I3YDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

765911:THIVI RS15355
gene id: 765911:THIVI_RS15355
uniprot id: I3YDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

765911:THIVI RS12580
gene id: 765911:THIVI_RS12580
uniprot id: I3YC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

765911:THIVI RS10835
gene id: 765911:THIVI_RS10835
uniprot id: I3YB22
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS21740
gene id: 765911:THIVI_RS21740
uniprot id: I3YH25
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

765911:THIVI RS14530
gene id: 765911:THIVI_RS14530
uniprot id: I3YD14
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

765911:THIVI RS05350
gene id: 765911:THIVI_RS05350
uniprot id: I3Y812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

765911:THIVI RS20265
gene id: 765911:THIVI_RS20265
uniprot id: I3YG89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

765911:THIVI RS22055
gene id: 765911:THIVI_RS22055
uniprot id: I3YH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

765911:THIVI RS17345
gene id: 765911:THIVI_RS17345
uniprot id: I3YEM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

765911:THIVI RS01755
gene id: 765911:THIVI_RS01755
uniprot id: I3Y615
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

765911:THIVI RS19360
gene id: 765911:THIVI_RS19360
uniprot id: I3YFS2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

765911:THIVI RS05110
gene id: 765911:THIVI_RS05110
uniprot id: I3Y7W0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

765911:THIVI RS15230
gene id: 765911:THIVI_RS15230
uniprot id: I3YDF2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

765911:THIVI RS14730
gene id: 765911:THIVI_RS14730
uniprot id: I3YD49
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS07565
gene id: 765911:THIVI_RS07565
uniprot id: I3Y987
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS04805
gene id: 765911:THIVI_RS04805
uniprot id: I3Y7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

765911:THIVI RS25745
gene id: 765911:THIVI_RS25745
uniprot id: I3YAT2
names: Subcellular Location Annotation
messages: Cell inner membrane

765911:THIVI RS02015
gene id: 765911:THIVI_RS02015
uniprot id: I3Y666
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

765911:THIVI RS20285
gene id: 765911:THIVI_RS20285
uniprot id: I3YG93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

765911:THIVI RS05165
gene id: 765911:THIVI_RS05165
uniprot id: I3Y7X1
names: Function
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS13375
gene id: 765911:THIVI_RS13375
uniprot id: I3YCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

765911:THIVI RS03605
gene id: 765911:THIVI_RS03605
uniprot id: I3Y724
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

765911:THIVI RS16755
gene id: 765911:THIVI_RS16755
uniprot id: I3YEA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

765911:THIVI RS01150
gene id: 765911:THIVI_RS01150
uniprot id: I3Y5N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS19995
gene id: 765911:THIVI_RS19995
uniprot id: I3YG40
names: Similarity
messages: Belongs to the peptidase U62 family.

765911:THIVI RS18285
gene id: 765911:THIVI_RS18285
uniprot id: I3YF54
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18620
gene id: 765911:THIVI_RS18620
uniprot id: I3YFC0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

765911:THIVI RS06455
gene id: 765911:THIVI_RS06455
uniprot id: I3Y8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

765911:THIVI RS19385
gene id: 765911:THIVI_RS19385
uniprot id: I3YFS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

765911:THIVI RS04455
gene id: 765911:THIVI_RS04455
uniprot id: I3Y7I0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS06780
gene id: 765911:THIVI_RS06780
uniprot id: I3Y8T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

765911:THIVI RS04545
gene id: 765911:THIVI_RS04545
uniprot id: I3Y7J8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS15720
gene id: 765911:THIVI_RS15720
uniprot id: I3YDP9
names: Similarity
messages: Belongs to the PrpD family.

765911:THIVI RS10995
gene id: 765911:THIVI_RS10995
uniprot id: I3YB55
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

765911:THIVI RS08370
gene id: 765911:THIVI_RS08370
uniprot id: I3Y9N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS01050
gene id: 765911:THIVI_RS01050
uniprot id: I3Y5L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

765911:THIVI RS12610
gene id: 765911:THIVI_RS12610
uniprot id: I3YC18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

765911:THIVI RS17885
gene id: 765911:THIVI_RS17885
uniprot id: I3YEX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS08745
gene id: 765911:THIVI_RS08745
uniprot id: I3Y9W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

765911:THIVI RS01325
gene id: 765911:THIVI_RS01325
uniprot id: I3Y5S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

765911:THIVI RS07200
gene id: 765911:THIVI_RS07200
uniprot id: I3Y920
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

765911:THIVI RS01165
gene id: 765911:THIVI_RS01165
uniprot id: I3Y5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

765911:THIVI RS10530
gene id: 765911:THIVI_RS10530
uniprot id: I3YAW0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

765911:THIVI RS02360
gene id: 765911:THIVI_RS02360
uniprot id: I3Y6D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

765911:THIVI RS14790
gene id: 765911:THIVI_RS14790
uniprot id: I3YD61
names: Similarity
messages: Belongs to the PhoU family.

765911:THIVI RS13310
gene id: 765911:THIVI_RS13310
uniprot id: I3YCD9
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

765911:THIVI RS02345
gene id: 765911:THIVI_RS02345
uniprot id: I3Y6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

765911:THIVI RS14780
gene id: 765911:THIVI_RS14780
uniprot id: I3YD59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS08530
gene id: 765911:THIVI_RS08530
uniprot id: I3Y9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

765911:THIVI RS12950
gene id: 765911:THIVI_RS12950
uniprot id: I3YC68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

765911:THIVI RS05515
gene id: 765911:THIVI_RS05515
uniprot id: I3Y844
names: Similarity
messages: Belongs to the peptidase A31 family.

765911:THIVI RS14490
gene id: 765911:THIVI_RS14490
uniprot id: I3YD06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

765911:THIVI RS00525
gene id: 765911:THIVI_RS00525
uniprot id: I3Y5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

765911:THIVI RS09615
gene id: 765911:THIVI_RS09615
uniprot id: I3YAD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

765911:THIVI RS01105
gene id: 765911:THIVI_RS01105
uniprot id: I3Y5N0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

765911:THIVI RS12340
gene id: 765911:THIVI_RS12340
uniprot id: I3YBW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

765911:THIVI RS03025
gene id: 765911:THIVI_RS03025
uniprot id: I3Y6Q9
names: Similarity
messages: Belongs to the thioredoxin family.

765911:THIVI RS16485
gene id: 765911:THIVI_RS16485
uniprot id: I3YE52
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

765911:THIVI RS16835
gene id: 765911:THIVI_RS16835
uniprot id: I3YEC2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03560
gene id: 765911:THIVI_RS03560
uniprot id: I3Y715
names: Similarity
messages: Belongs to the HSP15 family.

765911:THIVI RS05130
gene id: 765911:THIVI_RS05130
uniprot id: I3Y7W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765911:THIVI RS01870
gene id: 765911:THIVI_RS01870
uniprot id: I3Y637
names: Similarity
messages: Belongs to the type III secretion exporter family.

765911:THIVI RS04565
gene id: 765911:THIVI_RS04565
uniprot id: I3Y7K2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

765911:THIVI RS11655
gene id: 765911:THIVI_RS11655
uniprot id: I3YBI5
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

765911:THIVI RS18510
gene id: 765911:THIVI_RS18510
uniprot id: I3YF98
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

765911:THIVI RS17815
gene id: 765911:THIVI_RS17815
uniprot id: I3YEV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

765911:THIVI RS10240
gene id: 765911:THIVI_RS10240
uniprot id: I3YAQ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

765911:THIVI RS00100
gene id: 765911:THIVI_RS00100
uniprot id: I3Y540
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

765911:THIVI RS18695
gene id: 765911:THIVI_RS18695
uniprot id: I3YFD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

765911:THIVI RS16135
gene id: 765911:THIVI_RS16135
uniprot id: I3YDY4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

765911:THIVI RS02135
gene id: 765911:THIVI_RS02135
uniprot id: I3Y692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

765911:THIVI RS17930
gene id: 765911:THIVI_RS17930
uniprot id: I3YEY2
names: Similarity
messages: Belongs to the HypE family.

765911:THIVI RS08915
gene id: 765911:THIVI_RS08915
uniprot id: I3Y9Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

765911:THIVI RS12565
gene id: 765911:THIVI_RS12565
uniprot id: I3YC09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

765911:THIVI RS10395
gene id: 765911:THIVI_RS10395
uniprot id: I3YAT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS20345
gene id: 765911:THIVI_RS20345
uniprot id: I3YGA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

765911:THIVI RS16130
gene id: 765911:THIVI_RS16130
uniprot id: I3YDY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

765911:THIVI RS06845
gene id: 765911:THIVI_RS06845
uniprot id: I3Y8V2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS15420
gene id: 765911:THIVI_RS15420
uniprot id: I3YDI9
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

765911:THIVI RS06215
gene id: 765911:THIVI_RS06215
uniprot id: I3Y8I4
names: Similarity
messages: Belongs to the YciI family.

765911:THIVI RS15445
gene id: 765911:THIVI_RS15445
uniprot id: I3YDJ4
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS20700
gene id: 765911:THIVI_RS20700
uniprot id: I3YGH8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

765911:THIVI RS13315
gene id: 765911:THIVI_RS13315
uniprot id: I3YCE0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

765911:THIVI RS13745
gene id: 765911:THIVI_RS13745
uniprot id: I3YCM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

765911:THIVI RS21895
gene id: 765911:THIVI_RS21895
uniprot id: I3YH56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

765911:THIVI RS16150
gene id: 765911:THIVI_RS16150
uniprot id: I3YDY7
names: Similarity
messages: Belongs to the UPF0235 family.

765911:THIVI RS02200
gene id: 765911:THIVI_RS02200
uniprot id: I3Y6A0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

765911:THIVI RS05545
gene id: 765911:THIVI_RS05545
uniprot id: I3Y850
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01740
gene id: 765911:THIVI_RS01740
uniprot id: I3Y612
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS16205
gene id: 765911:THIVI_RS16205
uniprot id: I3YDZ5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

765911:THIVI RS06425
gene id: 765911:THIVI_RS06425
uniprot id: I3Y8M2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

765911:THIVI RS05030
gene id: 765911:THIVI_RS05030
uniprot id: I3Y7U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

765911:THIVI RS18970
gene id: 765911:THIVI_RS18970
uniprot id: I3YFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS20500
gene id: 765911:THIVI_RS20500
uniprot id: I3YGD7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

765911:THIVI RS00130
gene id: 765911:THIVI_RS00130
uniprot id: I3Y546
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

765911:THIVI RS21985
gene id: 765911:THIVI_RS21985
uniprot id: I3YH75
names: Similarity
messages: Belongs to the MEMO1 family.

765911:THIVI RS19725
gene id: 765911:THIVI_RS19725
uniprot id: I3YFY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

765911:THIVI RS11565
gene id: 765911:THIVI_RS11565
uniprot id: I3YBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

765911:THIVI RS19330
gene id: 765911:THIVI_RS19330
uniprot id: I3YFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

765911:THIVI RS20275
gene id: 765911:THIVI_RS20275
uniprot id: I3YG91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

765911:THIVI RS20895
gene id: 765911:THIVI_RS20895
uniprot id: I3YGL6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

765911:THIVI RS10450
gene id: 765911:THIVI_RS10450
uniprot id: I3YAU4
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

765911:THIVI RS13010
gene id: 765911:THIVI_RS13010
uniprot id: I3YC79
names: Similarity
messages: Belongs to the ABC transporter superfamily.

765911:THIVI RS03540
gene id: 765911:THIVI_RS03540
uniprot id: I3Y711
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

765911:THIVI RS20530
gene id: 765911:THIVI_RS20530
uniprot id: I3YGE3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS09050
gene id: 765911:THIVI_RS09050
uniprot id: I3YA19
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

765911:THIVI RS19220
gene id: 765911:THIVI_RS19220
uniprot id: I3YFP4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

765911:THIVI RS16385
gene id: 765911:THIVI_RS16385
uniprot id: I3YE31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

765911:THIVI RS06330
gene id: 765911:THIVI_RS06330
uniprot id: I3Y8K4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS00350
gene id: 765911:THIVI_RS00350
uniprot id: I3Y588
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS19270
gene id: 765911:THIVI_RS19270
uniprot id: I3YFQ4
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01405
gene id: 765911:THIVI_RS01405
uniprot id: I3Y5U4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

765911:THIVI RS21000
gene id: 765911:THIVI_RS21000
uniprot id: I3YGN7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

765911:THIVI RS18785
gene id: 765911:THIVI_RS18785
uniprot id: I3YFF6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

765911:THIVI RS04725
gene id: 765911:THIVI_RS04725
uniprot id: I3Y7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

765911:THIVI RS14865
gene id: 765911:THIVI_RS14865
uniprot id: I3YD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

765911:THIVI RS20780
gene id: 765911:THIVI_RS20780
uniprot id: I3YGJ3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

765911:THIVI RS08060
gene id: 765911:THIVI_RS08060
uniprot id: I3Y9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS08545
gene id: 765911:THIVI_RS08545
uniprot id: I3Y9S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS00515
gene id: 765911:THIVI_RS00515
uniprot id: I3Y5C0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS20380
gene id: 765911:THIVI_RS20380
uniprot id: I3YGB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

765911:THIVI RS12200
gene id: 765911:THIVI_RS12200
uniprot id: I3YBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS25795
gene id: 765911:THIVI_RS25795
uniprot id: I3YCB6
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS08945
gene id: 765911:THIVI_RS08945
uniprot id: I3YA01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

765911:THIVI RS03360
gene id: 765911:THIVI_RS03360
uniprot id: I3Y6X5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

765911:THIVI RS21035
gene id: 765911:THIVI_RS21035
uniprot id: I3YGP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765911:THIVI RS19040
gene id: 765911:THIVI_RS19040
uniprot id: I3YFK8
names: Similarity
messages: Belongs to the peptidase A31 family.

765911:THIVI RS12105
gene id: 765911:THIVI_RS12105
uniprot id: I3YBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

765911:THIVI RS17320
gene id: 765911:THIVI_RS17320
uniprot id: I3YEL8
names: Similarity
messages: Belongs to the GppA/Ppx family.

765911:THIVI RS10945
gene id: 765911:THIVI_RS10945
uniprot id: I3YB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

765911:THIVI RS05765
gene id: 765911:THIVI_RS05765
uniprot id: I3Y892
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

765911:THIVI RS18230
gene id: 765911:THIVI_RS18230
uniprot id: I3YF43
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

765911:THIVI RS13790
gene id: 765911:THIVI_RS13790
uniprot id: I3YCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

765911:THIVI RS20330
gene id: 765911:THIVI_RS20330
uniprot id: I3YGA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

765911:THIVI RS20280
gene id: 765911:THIVI_RS20280
uniprot id: I3YG92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

765911:THIVI RS02350
gene id: 765911:THIVI_RS02350
uniprot id: I3Y6C9
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

765911:THIVI RS10200
gene id: 765911:THIVI_RS10200
uniprot id: I3YAP8
names: Similarity
messages: Belongs to the XFP family.

765911:THIVI RS22110
gene id: 765911:THIVI_RS22110
uniprot id: I3YH98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

765911:THIVI RS20430
gene id: 765911:THIVI_RS20430
uniprot id: I3YGC3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

765911:THIVI RS00370
gene id: 765911:THIVI_RS00370
uniprot id: I3Y592
names: Cofactor
messages: Binds 3 [4Fe-4S] clusters.

765911:THIVI RS05950
gene id: 765911:THIVI_RS05950
uniprot id: I3Y8C5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

765911:THIVI RS19910
gene id: 765911:THIVI_RS19910
uniprot id: I3YG22
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

765911:THIVI RS17950
gene id: 765911:THIVI_RS17950
uniprot id: I3YEY6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

765911:THIVI RS06625
gene id: 765911:THIVI_RS06625
uniprot id: I3Y8Q5
names: Similarity
messages: Belongs to the UPF0260 family.

765911:THIVI RS15095
gene id: 765911:THIVI_RS15095
uniprot id: I3YDC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

765911:THIVI RS17230
gene id: 765911:THIVI_RS17230
uniprot id: I3YEK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

765911:THIVI RS01925
gene id: 765911:THIVI_RS01925
uniprot id: I3Y648
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

765911:THIVI RS05095
gene id: 765911:THIVI_RS05095
uniprot id: I3Y7V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

765911:THIVI RS07855
gene id: 765911:THIVI_RS07855
uniprot id: I3Y9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

765911:THIVI RS08600
gene id: 765911:THIVI_RS08600
uniprot id: I3Y9T3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

765911:THIVI RS08865
gene id: 765911:THIVI_RS08865
uniprot id: I3Y9Y4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS22685
gene id: 765911:THIVI_RS22685
uniprot id: I3Y9M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS20070
gene id: 765911:THIVI_RS20070
uniprot id: I3YG54
names: Similarity
messages: Belongs to the UPF0047 family.

765911:THIVI RS17965
gene id: 765911:THIVI_RS17965
uniprot id: I3YEY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

765911:THIVI RS13870
gene id: 765911:THIVI_RS13870
uniprot id: I3YCQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS09195
gene id: 765911:THIVI_RS09195
uniprot id: I3YA49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS13620
gene id: 765911:THIVI_RS13620
uniprot id: I3YCK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS10035
gene id: 765911:THIVI_RS10035
uniprot id: I3YAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

765911:THIVI RS13155
gene id: 765911:THIVI_RS13155
uniprot id: I3YCA8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

765911:THIVI RS10085
gene id: 765911:THIVI_RS10085
uniprot id: I3YAM6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS02705
gene id: 765911:THIVI_RS02705
uniprot id: I3Y6J7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

765911:THIVI RS10955
gene id: 765911:THIVI_RS10955
uniprot id: I3YB46
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

765911:THIVI RS20785
gene id: 765911:THIVI_RS20785
uniprot id: I3YGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

765911:THIVI RS12235
gene id: 765911:THIVI_RS12235
uniprot id: I3YBU3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

765911:THIVI RS01505
gene id: 765911:THIVI_RS01505
uniprot id: I3Y5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS09165
gene id: 765911:THIVI_RS09165
uniprot id: I3YA43
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

765911:THIVI RS21495
gene id: 765911:THIVI_RS21495
uniprot id: I3YGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS03500
gene id: 765911:THIVI_RS03500
uniprot id: I3Y703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

765911:THIVI RS11585
gene id: 765911:THIVI_RS11585
uniprot id: I3YBH1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

765911:THIVI RS21885
gene id: 765911:THIVI_RS21885
uniprot id: I3YH53
names: Similarity
messages: Belongs to the UPF0502 family.

765911:THIVI RS03075
gene id: 765911:THIVI_RS03075
uniprot id: I3Y6R9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

765911:THIVI RS16035
gene id: 765911:THIVI_RS16035
uniprot id: I3YDW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

765911:THIVI RS13925
gene id: 765911:THIVI_RS13925
uniprot id: I3YCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS21815
gene id: 765911:THIVI_RS21815
uniprot id: I3YH41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

765911:THIVI RS13410
gene id: 765911:THIVI_RS13410
uniprot id: I3YCF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

765911:THIVI RS11250
gene id: 765911:THIVI_RS11250
uniprot id: I3YBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

765911:THIVI RS19305
gene id: 765911:THIVI_RS19305
uniprot id: I3YFR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

765911:THIVI RS17535
gene id: 765911:THIVI_RS17535
uniprot id: I3YEQ5
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18550
gene id: 765911:THIVI_RS18550
uniprot id: I3YFA6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

765911:THIVI RS08445
gene id: 765911:THIVI_RS08445
uniprot id: I3Y9Q1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS10635
gene id: 765911:THIVI_RS10635
uniprot id: I3YAY2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

765911:THIVI RS08710
gene id: 765911:THIVI_RS08710
uniprot id: I3Y9V2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS17430
gene id: 765911:THIVI_RS17430
uniprot id: I3YEN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

765911:THIVI RS02970
gene id: 765911:THIVI_RS02970
uniprot id: I3Y6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS01765
gene id: 765911:THIVI_RS01765
uniprot id: I3Y617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

765911:THIVI RS11270
gene id: 765911:THIVI_RS11270
uniprot id: I3YBA9
names: Similarity
messages: Belongs to the UPF0102 family.

765911:THIVI RS14880
gene id: 765911:THIVI_RS14880
uniprot id: I3YD81
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

765911:THIVI RS20865
gene id: 765911:THIVI_RS20865
uniprot id: I3YGL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

765911:THIVI RS17300
gene id: 765911:THIVI_RS17300
uniprot id: I3YEL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

765911:THIVI RS13560
gene id: 765911:THIVI_RS13560
uniprot id: I3YCI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

765911:THIVI RS17675
gene id: 765911:THIVI_RS17675
uniprot id: I3YET2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

765911:THIVI RS11495
gene id: 765911:THIVI_RS11495
uniprot id: I3YBF2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

765911:THIVI RS04695
gene id: 765911:THIVI_RS04695
uniprot id: I3Y7N0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

765911:THIVI RS21100
gene id: 765911:THIVI_RS21100
uniprot id: I3YGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

765911:THIVI RS04355
gene id: 765911:THIVI_RS04355
uniprot id: I3Y7G0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

765911:THIVI RS09585
gene id: 765911:THIVI_RS09585
uniprot id: I3YAC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS15425
gene id: 765911:THIVI_RS15425
uniprot id: I3YDJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS09045
gene id: 765911:THIVI_RS09045
uniprot id: I3YA18
names: Similarity
messages: Belongs to the asparagine synthetase family.

765911:THIVI RS02380
gene id: 765911:THIVI_RS02380
uniprot id: I3Y6D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

765911:THIVI RS04380
gene id: 765911:THIVI_RS04380
uniprot id: I3Y7G5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

765911:THIVI RS18940
gene id: 765911:THIVI_RS18940
uniprot id: I3YFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

765911:THIVI RS18960
gene id: 765911:THIVI_RS18960
uniprot id: I3YFJ1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03015
gene id: 765911:THIVI_RS03015
uniprot id: I3Y6Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

765911:THIVI RS05980
gene id: 765911:THIVI_RS05980
uniprot id: I3Y8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

765911:THIVI RS14980
gene id: 765911:THIVI_RS14980
uniprot id: I3YDA1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

765911:THIVI RS11225
gene id: 765911:THIVI_RS11225
uniprot id: I3YBA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

765911:THIVI RS18255
gene id: 765911:THIVI_RS18255
uniprot id: I3YF48
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

765911:THIVI RS01175
gene id: 765911:THIVI_RS01175
uniprot id: I3Y5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

765911:THIVI RS01225
gene id: 765911:THIVI_RS01225
uniprot id: I3Y5Q3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS13110
gene id: 765911:THIVI_RS13110
uniprot id: I3YC99
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS03940
gene id: 765911:THIVI_RS03940
uniprot id: I3Y780
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

765911:THIVI RS15255
gene id: 765911:THIVI_RS15255
uniprot id: I3YDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS20075
gene id: 765911:THIVI_RS20075
uniprot id: I3YG55
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

765911:THIVI RS05035
gene id: 765911:THIVI_RS05035
uniprot id: I3Y7U5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

765911:THIVI RS22020
gene id: 765911:THIVI_RS22020
uniprot id: I3YH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS16125
gene id: 765911:THIVI_RS16125
uniprot id: I3YDY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

765911:THIVI RS11240
gene id: 765911:THIVI_RS11240
uniprot id: I3YBA3
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

765911:THIVI RS01995
gene id: 765911:THIVI_RS01995
uniprot id: I3Y662
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

765911:THIVI RS20410
gene id: 765911:THIVI_RS20410
uniprot id: I3YGB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

765911:THIVI RS13305
gene id: 765911:THIVI_RS13305
uniprot id: I3YCD8
names: Similarity
messages: Belongs to the NifX/NifY family.

765911:THIVI RS10670
gene id: 765911:THIVI_RS10670
uniprot id: I3YAY9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

765911:THIVI RS15115
gene id: 765911:THIVI_RS15115
uniprot id: I3YDC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS13900
gene id: 765911:THIVI_RS13900
uniprot id: I3YCQ7
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS11020
gene id: 765911:THIVI_RS11020
uniprot id: I3YB60
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

765911:THIVI RS04515
gene id: 765911:THIVI_RS04515
uniprot id: I3Y7J2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS15675
gene id: 765911:THIVI_RS15675
uniprot id: I3YDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

765911:THIVI RS10560
gene id: 765911:THIVI_RS10560
uniprot id: I3YAW6
names: Similarity
messages: Belongs to the BolA/IbaG family.

765911:THIVI RS21025
gene id: 765911:THIVI_RS21025
uniprot id: I3YGP1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

765911:THIVI RS16275
gene id: 765911:THIVI_RS16275
uniprot id: I3YE09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

765911:THIVI RS06690
gene id: 765911:THIVI_RS06690
uniprot id: I3Y8R8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02925
gene id: 765911:THIVI_RS02925
uniprot id: I3Y6N9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

765911:THIVI RS17475
gene id: 765911:THIVI_RS17475
uniprot id: I3YEP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

765911:THIVI RS04155
gene id: 765911:THIVI_RS04155
uniprot id: I3Y7B8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS04595
gene id: 765911:THIVI_RS04595
uniprot id: I3Y7K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

765911:THIVI RS05285
gene id: 765911:THIVI_RS05285
uniprot id: I3Y7Z8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

765911:THIVI RS14700
gene id: 765911:THIVI_RS14700
uniprot id: I3YD43
names: Similarity
messages: Belongs to the pirin family.

765911:THIVI RS12690
gene id: 765911:THIVI_RS12690
uniprot id: I3YC34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

765911:THIVI RS19440
gene id: 765911:THIVI_RS19440
uniprot id: I3YFT6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

765911:THIVI RS20575
gene id: 765911:THIVI_RS20575
uniprot id: I3YGF2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18590
gene id: 765911:THIVI_RS18590
uniprot id: I3YFB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS20760
gene id: 765911:THIVI_RS20760
uniprot id: I3YGJ0
names: Similarity
messages: Belongs to the ClpX chaperone family.

765911:THIVI RS14050
gene id: 765911:THIVI_RS14050
uniprot id: I3YCT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS11680
gene id: 765911:THIVI_RS11680
uniprot id: I3YBJ0
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS19155
gene id: 765911:THIVI_RS19155
uniprot id: I3YFN0
names: Similarity
messages: Belongs to the YkuD family.

765911:THIVI RS03960
gene id: 765911:THIVI_RS03960
uniprot id: I3Y784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

765911:THIVI RS13750
gene id: 765911:THIVI_RS13750
uniprot id: I3YCN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

765911:THIVI RS09670
gene id: 765911:THIVI_RS09670
uniprot id: I3YAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS04750
gene id: 765911:THIVI_RS04750
uniprot id: I3Y7P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

765911:THIVI RS06435
gene id: 765911:THIVI_RS06435
uniprot id: I3Y8M4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

765911:THIVI RS16145
gene id: 765911:THIVI_RS16145
uniprot id: I3YDY6
names: Similarity
messages: Belongs to the YggT family.

765911:THIVI RS01455
gene id: 765911:THIVI_RS01455
uniprot id: I3Y5V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS09220
gene id: 765911:THIVI_RS09220
uniprot id: I3YA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

765911:THIVI RS17405
gene id: 765911:THIVI_RS17405
uniprot id: I3YEN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS13875
gene id: 765911:THIVI_RS13875
uniprot id: I3YCQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

765911:THIVI RS14830
gene id: 765911:THIVI_RS14830
uniprot id: I3YD70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

765911:THIVI RS19730
gene id: 765911:THIVI_RS19730
uniprot id: I3YFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

765911:THIVI RS04400
gene id: 765911:THIVI_RS04400
uniprot id: I3Y7G9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

765911:THIVI RS03120
gene id: 765911:THIVI_RS03120
uniprot id: I3Y6S6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS18890
gene id: 765911:THIVI_RS18890
uniprot id: I3YFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

765911:THIVI RS06830
gene id: 765911:THIVI_RS06830
uniprot id: I3Y8U9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

765911:THIVI RS08095
gene id: 765911:THIVI_RS08095
uniprot id: I3Y9I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS05430
gene id: 765911:THIVI_RS05430
uniprot id: I3Y827
names: Similarity
messages: Belongs to the GARS family.

765911:THIVI RS19700
gene id: 765911:THIVI_RS19700
uniprot id: I3YFY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

765911:THIVI RS18405
gene id: 765911:THIVI_RS18405
uniprot id: I3YF77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 1 heme group per subunit.
messages: Binds 2 heme groups per subunit.
messages: C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

765911:THIVI RS19255
gene id: 765911:THIVI_RS19255
uniprot id: I3YFQ1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

765911:THIVI RS16050
gene id: 765911:THIVI_RS16050
uniprot id: I3YDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

765911:THIVI RS16075
gene id: 765911:THIVI_RS16075
uniprot id: I3YDX2
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS15525
gene id: 765911:THIVI_RS15525
uniprot id: I3YDL0
names: Similarity
messages: Belongs to the Smg family.

765911:THIVI RS13630
gene id: 765911:THIVI_RS13630
uniprot id: I3YCK3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

765911:THIVI RS02410
gene id: 765911:THIVI_RS02410
uniprot id: I3Y6E1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS22125
gene id: 765911:THIVI_RS22125
uniprot id: I3YHA2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

765911:THIVI RS22525
gene id: 765911:THIVI_RS22525
uniprot id: I3Y7E9
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

765911:THIVI RS09785
gene id: 765911:THIVI_RS09785
uniprot id: I3YAG7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

765911:THIVI RS13350
gene id: 765911:THIVI_RS13350
uniprot id: I3YCE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS22040
gene id: 765911:THIVI_RS22040
uniprot id: I3YH85
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS14890
gene id: 765911:THIVI_RS14890
uniprot id: I3YD83
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

765911:THIVI RS08735
gene id: 765911:THIVI_RS08735
uniprot id: I3Y9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

765911:THIVI RS10645
gene id: 765911:THIVI_RS10645
uniprot id: I3YAY4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS22365
gene id: 765911:THIVI_RS22365
uniprot id: I3YHF3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

765911:THIVI RS19760
gene id: 765911:THIVI_RS19760
uniprot id: I3YFZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS08460
gene id: 765911:THIVI_RS08460
uniprot id: I3Y9Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

765911:THIVI RS07475
gene id: 765911:THIVI_RS07475
uniprot id: I3Y970
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS20400
gene id: 765911:THIVI_RS20400
uniprot id: I3YGB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

765911:THIVI RS09355
gene id: 765911:THIVI_RS09355
uniprot id: I3YA73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS12740
gene id: 765911:THIVI_RS12740
uniprot id: I3YC43
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

765911:THIVI RS11370
gene id: 765911:THIVI_RS11370
uniprot id: I3YBC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

765911:THIVI RS20025
gene id: 765911:THIVI_RS20025
uniprot id: I3YG45
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS12230
gene id: 765911:THIVI_RS12230
uniprot id: I3YBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

765911:THIVI RS01555
gene id: 765911:THIVI_RS01555
uniprot id: I3Y5X4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

765911:THIVI RS20720
gene id: 765911:THIVI_RS20720
uniprot id: I3YGI2
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

765911:THIVI RS07470
gene id: 765911:THIVI_RS07470
uniprot id: I3Y969
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

765911:THIVI RS01285
gene id: 765911:THIVI_RS01285
uniprot id: I3Y5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

765911:THIVI RS03585
gene id: 765911:THIVI_RS03585
uniprot id: I3Y720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

765911:THIVI RS02020
gene id: 765911:THIVI_RS02020
uniprot id: I3Y667
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

765911:THIVI RS10080
gene id: 765911:THIVI_RS10080
uniprot id: I3YAM5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS07780
gene id: 765911:THIVI_RS07780
uniprot id: I3Y9C8
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

765911:THIVI RS20880
gene id: 765911:THIVI_RS20880
uniprot id: I3YGL3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

765911:THIVI RS01270
gene id: 765911:THIVI_RS01270
uniprot id: I3Y5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

765911:THIVI RS14580
gene id: 765911:THIVI_RS14580
uniprot id: I3YD23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

765911:THIVI RS06420
gene id: 765911:THIVI_RS06420
uniprot id: I3Y8M1
names: Similarity
messages: Belongs to the peptidase S49 family.

765911:THIVI RS16690
gene id: 765911:THIVI_RS16690
uniprot id: I3YE95
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01415
gene id: 765911:THIVI_RS01415
uniprot id: I3Y5U6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

765911:THIVI RS16785
gene id: 765911:THIVI_RS16785
uniprot id: I3YEB2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

765911:THIVI RS15935
gene id: 765911:THIVI_RS15935
uniprot id: U3GJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

765911:THIVI RS08835
gene id: 765911:THIVI_RS08835
uniprot id: I3Y9X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

765911:THIVI RS18175
gene id: 765911:THIVI_RS18175
uniprot id: I3YF33
names: Similarity
messages: Belongs to the HupH/HyaF family.

765911:THIVI RS20085
gene id: 765911:THIVI_RS20085
uniprot id: I3YG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

765911:THIVI RS18905
gene id: 765911:THIVI_RS18905
uniprot id: I3YFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS05125
gene id: 765911:THIVI_RS05125
uniprot id: I3Y7W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765911:THIVI RS00450
gene id: 765911:THIVI_RS00450
uniprot id: I3Y5A8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS10360
gene id: 765911:THIVI_RS10360
uniprot id: I3YAS6
names: Similarity
messages: Belongs to the hemerythrin family.

765911:THIVI RS00615
gene id: 765911:THIVI_RS00615
uniprot id: I3Y5D2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

765911:THIVI RS02105
gene id: 765911:THIVI_RS02105
uniprot id: I3Y687
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

765911:THIVI RS11160
gene id: 765911:THIVI_RS11160
uniprot id: I3YB87
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

765911:THIVI RS06665
gene id: 765911:THIVI_RS06665
uniprot id: I3Y8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS13475
gene id: 765911:THIVI_RS13475
uniprot id: I3YCH2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

765911:THIVI RS19900
gene id: 765911:THIVI_RS19900
uniprot id: I3YG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

765911:THIVI RS01335
gene id: 765911:THIVI_RS01335
uniprot id: I3Y5S6
names: Function
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

765911:THIVI RS18685
gene id: 765911:THIVI_RS18685
uniprot id: I3YFD6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

765911:THIVI RS05025
gene id: 765911:THIVI_RS05025
uniprot id: I3Y7U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS11180
gene id: 765911:THIVI_RS11180
uniprot id: I3YB91
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

765911:THIVI RS10900
gene id: 765911:THIVI_RS10900
uniprot id: I3YB35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

765911:THIVI RS14750
gene id: 765911:THIVI_RS14750
uniprot id: I3YD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

765911:THIVI RS15825
gene id: 765911:THIVI_RS15825
uniprot id: I3YDS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS06135
gene id: 765911:THIVI_RS06135
uniprot id: I3Y8G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

765911:THIVI RS08420
gene id: 765911:THIVI_RS08420
uniprot id: I3Y9P6
names: Similarity
messages: Belongs to the asparagine synthetase family.

765911:THIVI RS17285
gene id: 765911:THIVI_RS17285
uniprot id: I3YEL2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

765911:THIVI RS01770
gene id: 765911:THIVI_RS01770
uniprot id: U3GJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

765911:THIVI RS05190
gene id: 765911:THIVI_RS05190
uniprot id: I3Y7X7
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS18530
gene id: 765911:THIVI_RS18530
uniprot id: I3YFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

765911:THIVI RS19395
gene id: 765911:THIVI_RS19395
uniprot id: I3YFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS13265
gene id: 765911:THIVI_RS13265
uniprot id: I3YCD0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

765911:THIVI RS15415
gene id: 765911:THIVI_RS15415
uniprot id: I3YDI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS22345
gene id: 765911:THIVI_RS22345
uniprot id: I3YHE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

765911:THIVI RS16810
gene id: 765911:THIVI_RS16810
uniprot id: I3YEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

765911:THIVI RS03405
gene id: 765911:THIVI_RS03405
uniprot id: I3Y6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

765911:THIVI RS17850
gene id: 765911:THIVI_RS17850
uniprot id: I3YEW5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

765911:THIVI RS17425
gene id: 765911:THIVI_RS17425
uniprot id: I3YEN7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

765911:THIVI RS16675
gene id: 765911:THIVI_RS16675
uniprot id: I3YE91
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

765911:THIVI RS06355
gene id: 765911:THIVI_RS06355
uniprot id: I3Y8K8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS13335
gene id: 765911:THIVI_RS13335
uniprot id: I3YCE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

765911:THIVI RS08970
gene id: 765911:THIVI_RS08970
uniprot id: I3YA06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS05375
gene id: 765911:THIVI_RS05375
uniprot id: I3Y817
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS17270
gene id: 765911:THIVI_RS17270
uniprot id: I3YEK9
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS17565
gene id: 765911:THIVI_RS17565
uniprot id: I3YER1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

765911:THIVI RS09545
gene id: 765911:THIVI_RS09545
uniprot id: I3YAB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

765911:THIVI RS16140
gene id: 765911:THIVI_RS16140
uniprot id: I3YDY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

765911:THIVI RS18645
gene id: 765911:THIVI_RS18645
uniprot id: I3YFC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

765911:THIVI RS16395
gene id: 765911:THIVI_RS16395
uniprot id: I3YE33
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

765911:THIVI RS19945
gene id: 765911:THIVI_RS19945
uniprot id: I3YG29
names: Similarity
messages: Belongs to the CFA/CMAS family.

765911:THIVI RS11820
gene id: 765911:THIVI_RS11820
uniprot id: I3YBL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

765911:THIVI RS02595
gene id: 765911:THIVI_RS02595
uniprot id: I3Y6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

765911:THIVI RS10825
gene id: 765911:THIVI_RS10825
uniprot id: I3YB20
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

765911:THIVI RS18600
gene id: 765911:THIVI_RS18600
uniprot id: I3YFB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

765911:THIVI RS14365
gene id: 765911:THIVI_RS14365
uniprot id: I3YCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS00805
gene id: 765911:THIVI_RS00805
uniprot id: I3Y5H2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

765911:THIVI RS05290
gene id: 765911:THIVI_RS05290
uniprot id: I3Y7Z9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

765911:THIVI RS20310
gene id: 765911:THIVI_RS20310
uniprot id: I3YG98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

765911:THIVI RS02420
gene id: 765911:THIVI_RS02420
uniprot id: I3Y6E3
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

765911:THIVI RS08935
gene id: 765911:THIVI_RS08935
uniprot id: I3Y9Z9
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

765911:THIVI RS22220
gene id: 765911:THIVI_RS22220
uniprot id: I3YHC1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

765911:THIVI RS03595
gene id: 765911:THIVI_RS03595
uniprot id: I3Y722
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

765911:THIVI RS16330
gene id: 765911:THIVI_RS16330
uniprot id: I3YE20
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

765911:THIVI RS22445
gene id: 765911:THIVI_RS22445
uniprot id: I3Y655
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

765911:THIVI RS20935
gene id: 765911:THIVI_RS20935
uniprot id: I3YGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS03600
gene id: 765911:THIVI_RS03600
uniprot id: I3Y723
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

765911:THIVI RS03050
gene id: 765911:THIVI_RS03050
uniprot id: I3Y6R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

765911:THIVI RS04835
gene id: 765911:THIVI_RS04835
uniprot id: I3Y7Q7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS11320
gene id: 765911:THIVI_RS11320
uniprot id: I3YBB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

765911:THIVI RS02100
gene id: 765911:THIVI_RS02100
uniprot id: I3Y686
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

765911:THIVI RS14510
gene id: 765911:THIVI_RS14510
uniprot id: I3YD10
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS05265
gene id: 765911:THIVI_RS05265
uniprot id: I3Y7Z2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

765911:THIVI RS08595
gene id: 765911:THIVI_RS08595
uniprot id: I3Y9T2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02500
gene id: 765911:THIVI_RS02500
uniprot id: I3Y6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

765911:THIVI RS10675
gene id: 765911:THIVI_RS10675
uniprot id: I3YAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

765911:THIVI RS01530
gene id: 765911:THIVI_RS01530
uniprot id: I3Y5W9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

765911:THIVI RS09070
gene id: 765911:THIVI_RS09070
uniprot id: I3YA23
names: Similarity
messages: Belongs to the UPF0175 family.

765911:THIVI RS20245
gene id: 765911:THIVI_RS20245
uniprot id: I3YG85
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

765911:THIVI RS10800
gene id: 765911:THIVI_RS10800
uniprot id: I3YB14
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

765911:THIVI RS02355
gene id: 765911:THIVI_RS02355
uniprot id: I3Y6D0
names: Similarity
messages: Belongs to the NifZ family.

765911:THIVI RS14950
gene id: 765911:THIVI_RS14950
uniprot id: I3YD95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

765911:THIVI RS20350
gene id: 765911:THIVI_RS20350
uniprot id: I3YGA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

765911:THIVI RS16310
gene id: 765911:THIVI_RS16310
uniprot id: I3YE16
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

765911:THIVI RS07295
gene id: 765911:THIVI_RS07295
uniprot id: I3Y939
names: Similarity
messages: Belongs to the heat shock protein 90 family.

765911:THIVI RS18880
gene id: 765911:THIVI_RS18880
uniprot id: I3YFH6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS19215
gene id: 765911:THIVI_RS19215
uniprot id: I3YFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

765911:THIVI RS03065
gene id: 765911:THIVI_RS03065
uniprot id: I3Y6R7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

765911:THIVI RS16710
gene id: 765911:THIVI_RS16710
uniprot id: I3YE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

765911:THIVI RS04890
gene id: 765911:THIVI_RS04890
uniprot id: I3Y7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

765911:THIVI RS01790
gene id: 765911:THIVI_RS01790
uniprot id: U3GJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

765911:THIVI RS08455
gene id: 765911:THIVI_RS08455
uniprot id: I3Y9Q4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

765911:THIVI RS12265
gene id: 765911:THIVI_RS12265
uniprot id: I3YBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

765911:THIVI RS01160
gene id: 765911:THIVI_RS01160
uniprot id: I3Y5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

765911:THIVI RS05360
gene id: 765911:THIVI_RS05360
uniprot id: I3Y814
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

765911:THIVI RS20295
gene id: 765911:THIVI_RS20295
uniprot id: I3YG95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

765911:THIVI RS13060
gene id: 765911:THIVI_RS13060
uniprot id: I3YC89
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

765911:THIVI RS05775
gene id: 765911:THIVI_RS05775
uniprot id: I3Y894
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

765911:THIVI RS15375
gene id: 765911:THIVI_RS15375
uniprot id: I3YDI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

765911:THIVI RS11940
gene id: 765911:THIVI_RS11940
uniprot id: I3YBN7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03495
gene id: 765911:THIVI_RS03495
uniprot id: I3Y702
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

765911:THIVI RS05535
gene id: 765911:THIVI_RS05535
uniprot id: I3Y848
names: Similarity
messages: Belongs to the WrbA family.

765911:THIVI RS16470
gene id: 765911:THIVI_RS16470
uniprot id: I3YE49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS13585
gene id: 765911:THIVI_RS13585
uniprot id: I3YCJ4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

765911:THIVI RS10405
gene id: 765911:THIVI_RS10405
uniprot id: I3YAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

765911:THIVI RS15405
gene id: 765911:THIVI_RS15405
uniprot id: I3YDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

765911:THIVI RS05135
gene id: 765911:THIVI_RS05135
uniprot id: I3Y7W5
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01985
gene id: 765911:THIVI_RS01985
uniprot id: I3Y660
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

765911:THIVI RS05330
gene id: 765911:THIVI_RS05330
uniprot id: I3Y808
names: Similarity
messages: Belongs to the CutA family.

765911:THIVI RS02905
gene id: 765911:THIVI_RS02905
uniprot id: I3Y6N6
names: Similarity
messages: Belongs to the histone deacetylase family.

765911:THIVI RS06890
gene id: 765911:THIVI_RS06890
uniprot id: I3Y8W1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765911:THIVI RS03020
gene id: 765911:THIVI_RS03020
uniprot id: I3Y6Q8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS20620
gene id: 765911:THIVI_RS20620
uniprot id: I3YGG2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS12280
gene id: 765911:THIVI_RS12280
uniprot id: I3YBV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS14425
gene id: 765911:THIVI_RS14425
uniprot id: I3YCZ3
names: Similarity
messages: Belongs to the YkuD family.

765911:THIVI RS18130
gene id: 765911:THIVI_RS18130
uniprot id: I3YF25
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

765911:THIVI RS13670
gene id: 765911:THIVI_RS13670
uniprot id: I3YCL3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS00245
gene id: 765911:THIVI_RS00245
uniprot id: I3Y569
names: Similarity
messages: Belongs to the CapA family.

765911:THIVI RS11660
gene id: 765911:THIVI_RS11660
uniprot id: I3YBI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

765911:THIVI RS00495
gene id: 765911:THIVI_RS00495
uniprot id: I3Y5B6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

765911:THIVI RS21640
gene id: 765911:THIVI_RS21640
uniprot id: I3YH06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

765911:THIVI RS11570
gene id: 765911:THIVI_RS11570
uniprot id: I3YBG8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

765911:THIVI RS05045
gene id: 765911:THIVI_RS05045
uniprot id: I3Y7U7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

765911:THIVI RS13250
gene id: 765911:THIVI_RS13250
uniprot id: I3YCC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS15885
gene id: 765911:THIVI_RS15885
uniprot id: I3YDT2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

765911:THIVI RS20795
gene id: 765911:THIVI_RS20795
uniprot id: I3YGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

765911:THIVI RS08105
gene id: 765911:THIVI_RS08105
uniprot id: I3Y9I3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

765911:THIVI RS21190
gene id: 765911:THIVI_RS21190
uniprot id: I3YGS3
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

765911:THIVI RS12595
gene id: 765911:THIVI_RS12595
uniprot id: I3YC15
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS06145
gene id: 765911:THIVI_RS06145
uniprot id: I3Y8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS19250
gene id: 765911:THIVI_RS19250
uniprot id: I3YFQ0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

765911:THIVI RS09285
gene id: 765911:THIVI_RS09285
uniprot id: I3YA60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

765911:THIVI RS14450
gene id: 765911:THIVI_RS14450
uniprot id: U3GJL6
names: Similarity
messages: Belongs to the SCO1/2 family.

765911:THIVI RS10195
gene id: 765911:THIVI_RS10195
uniprot id: I3YAP7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

765911:THIVI RS05605
gene id: 765911:THIVI_RS05605
uniprot id: I3Y862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS16295
gene id: 765911:THIVI_RS16295
uniprot id: I3YE13
names: Similarity
messages: Belongs to the P(II) protein family.

765911:THIVI RS07920
gene id: 765911:THIVI_RS07920
uniprot id: I3Y9F0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

765911:THIVI RS18515
gene id: 765911:THIVI_RS18515
uniprot id: I3YF99
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

765911:THIVI RS14870
gene id: 765911:THIVI_RS14870
uniprot id: I3YD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS22205
gene id: 765911:THIVI_RS22205
uniprot id: I3YHB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS21690
gene id: 765911:THIVI_RS21690
uniprot id: I3YH16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

765911:THIVI RS18195
gene id: 765911:THIVI_RS18195
uniprot id: I3YF37
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS16000
gene id: 765911:THIVI_RS16000
uniprot id: I3YDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

765911:THIVI RS14085
gene id: 765911:THIVI_RS14085
uniprot id: I3YCT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

765911:THIVI RS18525
gene id: 765911:THIVI_RS18525
uniprot id: I3YFA1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

765911:THIVI RS11770
gene id: 765911:THIVI_RS11770
uniprot id: I3YBK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS17700
gene id: 765911:THIVI_RS17700
uniprot id: I3YET7
names: Similarity
messages: Belongs to the NifX/NifY family.

765911:THIVI RS21070
gene id: 765911:THIVI_RS21070
uniprot id: I3YGQ0
names: Similarity
messages: Belongs to the HupF/HypC family.

765911:THIVI RS19345
gene id: 765911:THIVI_RS19345
uniprot id: I3YFR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

765911:THIVI RS11545
gene id: 765911:THIVI_RS11545
uniprot id: I3YBG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

765911:THIVI RS13345
gene id: 765911:THIVI_RS13345
uniprot id: I3YCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

765911:THIVI RS06440
gene id: 765911:THIVI_RS06440
uniprot id: I3Y8M5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

765911:THIVI RS19035
gene id: 765911:THIVI_RS19035
uniprot id: I3YFK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS20815
gene id: 765911:THIVI_RS20815
uniprot id: I3YGK1
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

765911:THIVI RS04905
gene id: 765911:THIVI_RS04905
uniprot id: I3Y7R9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS14960
gene id: 765911:THIVI_RS14960
uniprot id: I3YD97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS04295
gene id: 765911:THIVI_RS04295
uniprot id: I3Y7E8
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

765911:THIVI RS07590
gene id: 765911:THIVI_RS07590
uniprot id: I3Y991
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

765911:THIVI RS04095
gene id: 765911:THIVI_RS04095
uniprot id: I3Y7A7
names: Similarity
messages: Belongs to the thioredoxin family.

765911:THIVI RS16160
gene id: 765911:THIVI_RS16160
uniprot id: I3YDY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

765911:THIVI RS02245
gene id: 765911:THIVI_RS02245
uniprot id: I3Y6A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

765911:THIVI RS16085
gene id: 765911:THIVI_RS16085
uniprot id: I3YDX4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

765911:THIVI RS14110
gene id: 765911:THIVI_RS14110
uniprot id: I3YCU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

765911:THIVI RS00500
gene id: 765911:THIVI_RS00500
uniprot id: I3Y5B7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

765911:THIVI RS00470
gene id: 765911:THIVI_RS00470
uniprot id: I3Y5B2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

765911:THIVI RS00440
gene id: 765911:THIVI_RS00440
uniprot id: I3Y5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

765911:THIVI RS01805
gene id: 765911:THIVI_RS01805
uniprot id: I3Y625
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

765911:THIVI RS06840
gene id: 765911:THIVI_RS06840
uniprot id: I3Y8V1
names: Subcellular Location Annotation
messages: Cell outer membrane

765911:THIVI RS20480
gene id: 765911:THIVI_RS20480
uniprot id: I3YGD3
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

765911:THIVI RS09270
gene id: 765911:THIVI_RS09270
uniprot id: I3YA58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

765911:THIVI RS12570
gene id: 765911:THIVI_RS12570
uniprot id: I3YC10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

765911:THIVI RS16705
gene id: 765911:THIVI_RS16705
uniprot id: I3YE98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

765911:THIVI RS19505
gene id: 765911:THIVI_RS19505
uniprot id: I3YFU1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS00890
gene id: 765911:THIVI_RS00890
uniprot id: I3Y5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS13735
gene id: 765911:THIVI_RS13735
uniprot id: I3YCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

765911:THIVI RS13860
gene id: 765911:THIVI_RS13860
uniprot id: I3YCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS12330
gene id: 765911:THIVI_RS12330
uniprot id: I3YBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS18885
gene id: 765911:THIVI_RS18885
uniprot id: I3YFH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

765911:THIVI RS22925
gene id: 765911:THIVI_RS22925
uniprot id: I3YDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

765911:THIVI RS00430
gene id: 765911:THIVI_RS00430
uniprot id: I3Y5A4
names: Similarity
messages: Belongs to the universal stress protein A family.

765911:THIVI RS20190
gene id: 765911:THIVI_RS20190
uniprot id: I3YG78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

765911:THIVI RS14735
gene id: 765911:THIVI_RS14735
uniprot id: I3YD50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

765911:THIVI RS13185
gene id: 765911:THIVI_RS13185
uniprot id: I3YCB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

765911:THIVI RS09800
gene id: 765911:THIVI_RS09800
uniprot id: I3YAH0
names: Similarity
messages: Belongs to the DEAD box helicase family.

765911:THIVI RS15055
gene id: 765911:THIVI_RS15055
uniprot id: I3YDB7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

765911:THIVI RS13880
gene id: 765911:THIVI_RS13880
uniprot id: I3YCQ3
names: Similarity
messages: Belongs to the glutamate synthase family.

765911:THIVI RS22155
gene id: 765911:THIVI_RS22155
uniprot id: I3YHA8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01210
gene id: 765911:THIVI_RS01210
uniprot id: I3Y5Q0
names: Similarity
messages: Belongs to the threonine synthase family.

765911:THIVI RS16240
gene id: 765911:THIVI_RS16240
uniprot id: I3YE02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

765911:THIVI RS20255
gene id: 765911:THIVI_RS20255
uniprot id: I3YG87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

765911:THIVI RS12150
gene id: 765911:THIVI_RS12150
uniprot id: I3YBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

765911:THIVI RS14515
gene id: 765911:THIVI_RS14515
uniprot id: I3YD11
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18850
gene id: 765911:THIVI_RS18850
uniprot id: I3YFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

765911:THIVI RS13200
gene id: 765911:THIVI_RS13200
uniprot id: I3YCB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

765911:THIVI RS08790
gene id: 765911:THIVI_RS08790
uniprot id: I3Y9X0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

765911:THIVI RS15585
gene id: 765911:THIVI_RS15585
uniprot id: I3YDM3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02460
gene id: 765911:THIVI_RS02460
uniprot id: I3Y6F0
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS07575
gene id: 765911:THIVI_RS07575
uniprot id: I3Y988
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

765911:THIVI RS05555
gene id: 765911:THIVI_RS05555
uniprot id: I3Y852
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

765911:THIVI RS20205
gene id: 765911:THIVI_RS20205
uniprot id: I3YG81
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

765911:THIVI RS19280
gene id: 765911:THIVI_RS19280
uniprot id: I3YFQ6
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

765911:THIVI RS03255
gene id: 765911:THIVI_RS03255
uniprot id: I3Y6V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

765911:THIVI RS10060
gene id: 765911:THIVI_RS10060
uniprot id: I3YAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

765911:THIVI RS18910
gene id: 765911:THIVI_RS18910
uniprot id: I3YFI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS20200
gene id: 765911:THIVI_RS20200
uniprot id: I3YG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS14155
gene id: 765911:THIVI_RS14155
uniprot id: I3YCV2
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

765911:THIVI RS07535
gene id: 765911:THIVI_RS07535
uniprot id: I3Y981
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

765911:THIVI RS13805
gene id: 765911:THIVI_RS13805
uniprot id: I3YCP0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

765911:THIVI RS22030
gene id: 765911:THIVI_RS22030
uniprot id: I3YH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS09985
gene id: 765911:THIVI_RS09985
uniprot id: I3YAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS18915
gene id: 765911:THIVI_RS18915
uniprot id: I3YFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS19710
gene id: 765911:THIVI_RS19710
uniprot id: I3YFY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

765911:THIVI RS02655
gene id: 765911:THIVI_RS02655
uniprot id: I3Y6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

765911:THIVI RS17960
gene id: 765911:THIVI_RS17960
uniprot id: I3YEY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

765911:THIVI RS10370
gene id: 765911:THIVI_RS10370
uniprot id: I3YAS8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

765911:THIVI RS20845
gene id: 765911:THIVI_RS20845
uniprot id: I3YGK5
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS06605
gene id: 765911:THIVI_RS06605
uniprot id: I3Y8Q1
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

765911:THIVI RS05465
gene id: 765911:THIVI_RS05465
uniprot id: I3Y834
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

765911:THIVI RS20300
gene id: 765911:THIVI_RS20300
uniprot id: I3YG96
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

765911:THIVI RS01695
gene id: 765911:THIVI_RS01695
uniprot id: I3Y603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

765911:THIVI RS01760
gene id: 765911:THIVI_RS01760
uniprot id: I3Y616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

765911:THIVI RS14915
gene id: 765911:THIVI_RS14915
uniprot id: I3YD88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS15380
gene id: 765911:THIVI_RS15380
uniprot id: I3YDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

765911:THIVI RS01185
gene id: 765911:THIVI_RS01185
uniprot id: I3Y5P5
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

765911:THIVI RS04585
gene id: 765911:THIVI_RS04585
uniprot id: I3Y7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

765911:THIVI RS08905
gene id: 765911:THIVI_RS08905
uniprot id: I3Y9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

765911:THIVI RS19105
gene id: 765911:THIVI_RS19105
uniprot id: I3YFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

765911:THIVI RS06790
gene id: 765911:THIVI_RS06790
uniprot id: I3Y8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

765911:THIVI RS08805
gene id: 765911:THIVI_RS08805
uniprot id: I3Y9X2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS06775
gene id: 765911:THIVI_RS06775
uniprot id: I3Y8T8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS14745
gene id: 765911:THIVI_RS14745
uniprot id: I3YD52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS19510
gene id: 765911:THIVI_RS19510
uniprot id: I3YFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS10595
gene id: 765911:THIVI_RS10595
uniprot id: I3YAX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

765911:THIVI RS08705
gene id: 765911:THIVI_RS08705
uniprot id: I3Y9V0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

765911:THIVI RS19010
gene id: 765911:THIVI_RS19010
uniprot id: I3YFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

765911:THIVI RS06815
gene id: 765911:THIVI_RS06815
uniprot id: I3Y8U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

765911:THIVI RS10135
gene id: 765911:THIVI_RS10135
uniprot id: I3YAN5
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS08490
gene id: 765911:THIVI_RS08490
uniprot id: I3Y9R1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

765911:THIVI RS01075
gene id: 765911:THIVI_RS01075
uniprot id: I3Y5M3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

765911:THIVI RS05910
gene id: 765911:THIVI_RS05910
uniprot id: I3Y8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

765911:THIVI RS11335
gene id: 765911:THIVI_RS11335
uniprot id: I3YBC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765911:THIVI RS14575
gene id: 765911:THIVI_RS14575
uniprot id: I3YD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

765911:THIVI RS08410
gene id: 765911:THIVI_RS08410
uniprot id: I3Y9P4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

765911:THIVI RS17545
gene id: 765911:THIVI_RS17545
uniprot id: I3YEQ7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

765911:THIVI RS05150
gene id: 765911:THIVI_RS05150
uniprot id: I3Y7W8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02600
gene id: 765911:THIVI_RS02600
uniprot id: I3Y6H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

765911:THIVI RS02620
gene id: 765911:THIVI_RS02620
uniprot id: I3Y6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

765911:THIVI RS03135
gene id: 765911:THIVI_RS03135
uniprot id: I3Y6S9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS02395
gene id: 765911:THIVI_RS02395
uniprot id: I3Y6D8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS19915
gene id: 765911:THIVI_RS19915
uniprot id: I3YG23
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

765911:THIVI RS05060
gene id: 765911:THIVI_RS05060
uniprot id: I3Y7V0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

765911:THIVI RS08685
gene id: 765911:THIVI_RS08685
uniprot id: I3Y9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

765911:THIVI RS10970
gene id: 765911:THIVI_RS10970
uniprot id: I3YB49
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

765911:THIVI RS05145
gene id: 765911:THIVI_RS05145
uniprot id: I3Y7W7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS19315
gene id: 765911:THIVI_RS19315
uniprot id: I3YFR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

765911:THIVI RS14370
gene id: 765911:THIVI_RS14370
uniprot id: I3YCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS15820
gene id: 765911:THIVI_RS15820
uniprot id: I3YDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS08900
gene id: 765911:THIVI_RS08900
uniprot id: I3Y9Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

765911:THIVI RS19400
gene id: 765911:THIVI_RS19400
uniprot id: I3YFS9
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

765911:THIVI RS07080
gene id: 765911:THIVI_RS07080
uniprot id: I3Y900
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

765911:THIVI RS08065
gene id: 765911:THIVI_RS08065
uniprot id: I3Y9H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

765911:THIVI RS15855
gene id: 765911:THIVI_RS15855
uniprot id: I3YDS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

765911:THIVI RS14895
gene id: 765911:THIVI_RS14895
uniprot id: I3YD84
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

765911:THIVI RS12550
gene id: 765911:THIVI_RS12550
uniprot id: I3YC06
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

765911:THIVI RS03770
gene id: 765911:THIVI_RS03770
uniprot id: U3GKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

765911:THIVI RS14975
gene id: 765911:THIVI_RS14975
uniprot id: I3YDA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS20315
gene id: 765911:THIVI_RS20315
uniprot id: I3YG99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

765911:THIVI RS10895
gene id: 765911:THIVI_RS10895
uniprot id: I3YB34
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01635
gene id: 765911:THIVI_RS01635
uniprot id: I3Y5Z0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS12535
gene id: 765911:THIVI_RS12535
uniprot id: I3YC03
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

765911:THIVI RS11200
gene id: 765911:THIVI_RS11200
uniprot id: I3YB95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

765911:THIVI RS16735
gene id: 765911:THIVI_RS16735
uniprot id: I3YEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765911:THIVI RS17725
gene id: 765911:THIVI_RS17725
uniprot id: I3YEU1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

765911:THIVI RS00150
gene id: 765911:THIVI_RS00150
uniprot id: I3Y550
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

765911:THIVI RS10230
gene id: 765911:THIVI_RS10230
uniprot id: I3YAQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

765911:THIVI RS18170
gene id: 765911:THIVI_RS18170
uniprot id: I3YF32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

765911:THIVI RS07560
gene id: 765911:THIVI_RS07560
uniprot id: I3Y986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

765911:THIVI RS08730
gene id: 765911:THIVI_RS08730
uniprot id: I3Y9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

765911:THIVI RS18965
gene id: 765911:THIVI_RS18965
uniprot id: I3YFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

765911:THIVI RS16895
gene id: 765911:THIVI_RS16895
uniprot id: I3YED3
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS02955
gene id: 765911:THIVI_RS02955
uniprot id: I3Y6P5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS04740
gene id: 765911:THIVI_RS04740
uniprot id: I3Y7P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

765911:THIVI RS15365
gene id: 765911:THIVI_RS15365
uniprot id: I3YDH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

765911:THIVI RS02990
gene id: 765911:THIVI_RS02990
uniprot id: I3Y6Q2
names: Similarity
messages: Belongs to the peptidase S8 family.

765911:THIVI RS13785
gene id: 765911:THIVI_RS13785
uniprot id: I3YCN6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS08655
gene id: 765911:THIVI_RS08655
uniprot id: I3Y9U2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

765911:THIVI RS12540
gene id: 765911:THIVI_RS12540
uniprot id: I3YC04
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

765911:THIVI RS17735
gene id: 765911:THIVI_RS17735
uniprot id: I3YEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS04105
gene id: 765911:THIVI_RS04105
uniprot id: I3Y7A9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

765911:THIVI RS01305
gene id: 765911:THIVI_RS01305
uniprot id: I3Y5S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

765911:THIVI RS12575
gene id: 765911:THIVI_RS12575
uniprot id: I3YC11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

765911:THIVI RS04730
gene id: 765911:THIVI_RS04730
uniprot id: I3Y7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

765911:THIVI RS16730
gene id: 765911:THIVI_RS16730
uniprot id: I3YEA1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

765911:THIVI RS20165
gene id: 765911:THIVI_RS20165
uniprot id: I3YG74
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

765911:THIVI RS13105
gene id: 765911:THIVI_RS13105
uniprot id: I3YC98
names: Similarity
messages: Belongs to the HupH/HyaF family.

765911:THIVI RS18780
gene id: 765911:THIVI_RS18780
uniprot id: I3YFF5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

765911:THIVI RS03390
gene id: 765911:THIVI_RS03390
uniprot id: I3Y6Y2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

765911:THIVI RS13605
gene id: 765911:THIVI_RS13605
uniprot id: I3YCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS14055
gene id: 765911:THIVI_RS14055
uniprot id: I3YCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

765911:THIVI RS08335
gene id: 765911:THIVI_RS08335
uniprot id: I3Y9M9
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS21810
gene id: 765911:THIVI_RS21810
uniprot id: I3YH40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

765911:THIVI RS08365
gene id: 765911:THIVI_RS08365
uniprot id: I3Y9N5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS02755
gene id: 765911:THIVI_RS02755
uniprot id: I3Y6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

765911:THIVI RS05010
gene id: 765911:THIVI_RS05010
uniprot id: I3Y7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS17305
gene id: 765911:THIVI_RS17305
uniprot id: I3YEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

765911:THIVI RS01055
gene id: 765911:THIVI_RS01055
uniprot id: I3Y5L9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

765911:THIVI RS15930
gene id: 765911:THIVI_RS15930
uniprot id: I3YDU2
names: Similarity
messages: Belongs to the SufE family.

765911:THIVI RS14190
gene id: 765911:THIVI_RS14190
uniprot id: I3YCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

765911:THIVI RS15385
gene id: 765911:THIVI_RS15385
uniprot id: I3YDI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765911:THIVI RS21820
gene id: 765911:THIVI_RS21820
uniprot id: I3YH42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

765911:THIVI RS11190
gene id: 765911:THIVI_RS11190
uniprot id: I3YB93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

765911:THIVI RS14145
gene id: 765911:THIVI_RS14145
uniprot id: I3YCV0
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01540
gene id: 765911:THIVI_RS01540
uniprot id: I3Y5X1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

765911:THIVI RS03550
gene id: 765911:THIVI_RS03550
uniprot id: I3Y713
names: Similarity
messages: Belongs to the peptidase M1 family.

765911:THIVI RS15395
gene id: 765911:THIVI_RS15395
uniprot id: I3YDI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

765911:THIVI RS12180
gene id: 765911:THIVI_RS12180
uniprot id: I3YBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

765911:THIVI RS03070
gene id: 765911:THIVI_RS03070
uniprot id: I3Y6R8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

765911:THIVI RS05005
gene id: 765911:THIVI_RS05005
uniprot id: I3Y7T9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

765911:THIVI RS10770
gene id: 765911:THIVI_RS10770
uniprot id: I3YB08
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

765911:THIVI RS08555
gene id: 765911:THIVI_RS08555
uniprot id: I3Y9S4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

765911:THIVI RS05470
gene id: 765911:THIVI_RS05470
uniprot id: I3Y835
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

765911:THIVI RS20260
gene id: 765911:THIVI_RS20260
uniprot id: I3YG88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

765911:THIVI RS21060
gene id: 765911:THIVI_RS21060
uniprot id: I3YGP8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

765911:THIVI RS03240
gene id: 765911:THIVI_RS03240
uniprot id: I3Y6V0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765911:THIVI RS03710
gene id: 765911:THIVI_RS03710
uniprot id: I3Y744
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS05510
gene id: 765911:THIVI_RS05510
uniprot id: I3Y843
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS15860
gene id: 765911:THIVI_RS15860
uniprot id: I3YDS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

765911:THIVI RS05180
gene id: 765911:THIVI_RS05180
uniprot id: I3Y7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS18455
gene id: 765911:THIVI_RS18455
uniprot id: I3YF87
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

765911:THIVI RS00310
gene id: 765911:THIVI_RS00310
uniprot id: I3Y580
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

765911:THIVI RS01445
gene id: 765911:THIVI_RS01445
uniprot id: I3Y5V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

765911:THIVI RS15100
gene id: 765911:THIVI_RS15100
uniprot id: I3YDC6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

765911:THIVI RS01430
gene id: 765911:THIVI_RS01430
uniprot id: I3Y5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

765911:THIVI RS03105
gene id: 765911:THIVI_RS03105
uniprot id: I3Y6S3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

765911:THIVI RS20355
gene id: 765911:THIVI_RS20355
uniprot id: I3YGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

765911:THIVI RS03225
gene id: 765911:THIVI_RS03225
uniprot id: I3Y6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

765911:THIVI RS03515
gene id: 765911:THIVI_RS03515
uniprot id: I3Y706
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS05475
gene id: 765911:THIVI_RS05475
uniprot id: I3Y836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

765911:THIVI RS03465
gene id: 765911:THIVI_RS03465
uniprot id: I3Y6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

765911:THIVI RS16405
gene id: 765911:THIVI_RS16405
uniprot id: I3YE35
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

765911:THIVI RS02995
gene id: 765911:THIVI_RS02995
uniprot id: I3Y6Q3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

765911:THIVI RS08605
gene id: 765911:THIVI_RS08605
uniprot id: I3Y9T4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

765911:THIVI RS19745
gene id: 765911:THIVI_RS19745
uniprot id: I3YFZ1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS12585
gene id: 765911:THIVI_RS12585
uniprot id: I3YC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

765911:THIVI RS14705
gene id: 765911:THIVI_RS14705
uniprot id: I3YD44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

765911:THIVI RS12345
gene id: 765911:THIVI_RS12345
uniprot id: I3YBW6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

765911:THIVI RS15150
gene id: 765911:THIVI_RS15150
uniprot id: I3YDD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

765911:THIVI RS22340
gene id: 765911:THIVI_RS22340
uniprot id: I3YHE8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

765911:THIVI RS22225
gene id: 765911:THIVI_RS22225
uniprot id: I3YHC2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

765911:THIVI RS18215
gene id: 765911:THIVI_RS18215
uniprot id: I3YF40
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

765911:THIVI RS01280
gene id: 765911:THIVI_RS01280
uniprot id: I3Y5R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

765911:THIVI RS13610
gene id: 765911:THIVI_RS13610
uniprot id: I3YCJ9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS19275
gene id: 765911:THIVI_RS19275
uniprot id: I3YFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

765911:THIVI RS01410
gene id: 765911:THIVI_RS01410
uniprot id: I3Y5U5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

765911:THIVI RS20475
gene id: 765911:THIVI_RS20475
uniprot id: I3YGD2
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

765911:THIVI RS00320
gene id: 765911:THIVI_RS00320
uniprot id: I3Y582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Belongs to the universal stress protein A family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS02935
gene id: 765911:THIVI_RS02935
uniprot id: I3Y6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

765911:THIVI RS08840
gene id: 765911:THIVI_RS08840
uniprot id: I3Y9X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

765911:THIVI RS16215
gene id: 765911:THIVI_RS16215
uniprot id: I3YDZ7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

765911:THIVI RS18115
gene id: 765911:THIVI_RS18115
uniprot id: I3YF22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

765911:THIVI RS16870
gene id: 765911:THIVI_RS16870
uniprot id: I3YEC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

765911:THIVI RS16700
gene id: 765911:THIVI_RS16700
uniprot id: I3YE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

765911:THIVI RS08590
gene id: 765911:THIVI_RS08590
uniprot id: I3Y9T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

765911:THIVI RS05050
gene id: 765911:THIVI_RS05050
uniprot id: I3Y7U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

765911:THIVI RS13245
gene id: 765911:THIVI_RS13245
uniprot id: I3YCC6
names: Similarity
messages: Belongs to the YfgM family.

765911:THIVI RS05550
gene id: 765911:THIVI_RS05550
uniprot id: I3Y851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

765911:THIVI RS20825
gene id: 765911:THIVI_RS20825
uniprot id: I3YGK3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

765911:THIVI RS11010
gene id: 765911:THIVI_RS11010
uniprot id: I3YB58
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

765911:THIVI RS21660
gene id: 765911:THIVI_RS21660
uniprot id: I3YH10
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

765911:THIVI RS08560
gene id: 765911:THIVI_RS08560
uniprot id: I3Y9S5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS06820
gene id: 765911:THIVI_RS06820
uniprot id: I3Y8U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS11710
gene id: 765911:THIVI_RS11710
uniprot id: I3YBJ6
names: Similarity
messages: Belongs to the pyruvate kinase family.

765911:THIVI RS00120
gene id: 765911:THIVI_RS00120
uniprot id: I3Y544
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

765911:THIVI RS07220
gene id: 765911:THIVI_RS07220
uniprot id: I3Y924
names: Similarity
messages: Belongs to the CIA30 family.

765911:THIVI RS08535
gene id: 765911:THIVI_RS08535
uniprot id: I3Y9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

765911:THIVI RS14385
gene id: 765911:THIVI_RS14385
uniprot id: I3YCY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765911:THIVI RS18930
gene id: 765911:THIVI_RS18930
uniprot id: I3YFI5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

765911:THIVI RS16655
gene id: 765911:THIVI_RS16655
uniprot id: I3YE86
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

765911:THIVI RS03790
gene id: 765911:THIVI_RS03790
uniprot id: I3Y759
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

765911:THIVI RS05780
gene id: 765911:THIVI_RS05780
uniprot id: I3Y895
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

765911:THIVI RS16090
gene id: 765911:THIVI_RS16090
uniprot id: I3YDX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS20875
gene id: 765911:THIVI_RS20875
uniprot id: I3YGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

765911:THIVI RS06080
gene id: 765911:THIVI_RS06080
uniprot id: I3Y8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

765911:THIVI RS00115
gene id: 765911:THIVI_RS00115
uniprot id: I3Y543
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

765911:THIVI RS11905
gene id: 765911:THIVI_RS11905
uniprot id: I3YBN0
names: Similarity
messages: Belongs to the PspA/IM30 family.

765911:THIVI RS10840
gene id: 765911:THIVI_RS10840
uniprot id: I3YB23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

765911:THIVI RS08585
gene id: 765911:THIVI_RS08585
uniprot id: I3Y9T0
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

765911:THIVI RS22260
gene id: 765911:THIVI_RS22260
uniprot id: I3YHC8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

765911:THIVI RS05645
gene id: 765911:THIVI_RS05645
uniprot id: I3Y870
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

765911:THIVI RS09160
gene id: 765911:THIVI_RS09160
uniprot id: I3YA42
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

765911:THIVI RS16300
gene id: 765911:THIVI_RS16300
uniprot id: I3YE14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

765911:THIVI RS08965
gene id: 765911:THIVI_RS08965
uniprot id: I3YA05
names: Similarity
messages: Belongs to the PhoH family.

765911:THIVI RS03270
gene id: 765911:THIVI_RS03270
uniprot id: I3Y6V7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

765911:THIVI RS20195
gene id: 765911:THIVI_RS20195
uniprot id: I3YG79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

765911:THIVI RS10565
gene id: 765911:THIVI_RS10565
uniprot id: I3YAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

765911:THIVI RS19665
gene id: 765911:THIVI_RS19665
uniprot id: I3YFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

765911:THIVI RS03290
gene id: 765911:THIVI_RS03290
uniprot id: I3Y6W1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

765911:THIVI RS17680
gene id: 765911:THIVI_RS17680
uniprot id: I3YET3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

765911:THIVI RS16610
gene id: 765911:THIVI_RS16610
uniprot id: I3YE77
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS21045
gene id: 765911:THIVI_RS21045
uniprot id: I3YGP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

765911:THIVI RS11330
gene id: 765911:THIVI_RS11330
uniprot id: I3YBC1
names: Similarity
messages: Belongs to the pyruvate kinase family.

765911:THIVI RS07545
gene id: 765911:THIVI_RS07545
uniprot id: I3Y983
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

765911:THIVI RS06885
gene id: 765911:THIVI_RS06885
uniprot id: I3Y8W0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

765911:THIVI RS04500
gene id: 765911:THIVI_RS04500
uniprot id: I3Y7I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS13600
gene id: 765911:THIVI_RS13600
uniprot id: I3YCJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

765911:THIVI RS18110
gene id: 765911:THIVI_RS18110
uniprot id: I3YF21
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

765911:THIVI RS00135
gene id: 765911:THIVI_RS00135
uniprot id: I3Y547
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

765911:THIVI RS12260
gene id: 765911:THIVI_RS12260
uniprot id: I3YBU8
names: Similarity
messages: Belongs to the UPF0166 family.

765911:THIVI RS06940
gene id: 765911:THIVI_RS06940
uniprot id: I3Y8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

765911:THIVI RS20375
gene id: 765911:THIVI_RS20375
uniprot id: I3YGB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

765911:THIVI RS20860
gene id: 765911:THIVI_RS20860
uniprot id: I3YGK9
names: Similarity
messages: Belongs to the TelA family.

765911:THIVI RS19930
gene id: 765911:THIVI_RS19930
uniprot id: I3YG26
names: Similarity
messages: Belongs to the peptidase U62 family.

765911:THIVI RS12545
gene id: 765911:THIVI_RS12545
uniprot id: I3YC05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

765911:THIVI RS01920
gene id: 765911:THIVI_RS01920
uniprot id: I3Y647
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

765911:THIVI RS01730
gene id: 765911:THIVI_RS01730
uniprot id: I3Y610
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

765911:THIVI RS04330
gene id: 765911:THIVI_RS04330
uniprot id: I3Y7F5
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

765911:THIVI RS12275
gene id: 765911:THIVI_RS12275
uniprot id: I3YBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

765911:THIVI RS11230
gene id: 765911:THIVI_RS11230
uniprot id: I3YBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS03180
gene id: 765911:THIVI_RS03180
uniprot id: I3Y6T8
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS14095
gene id: 765911:THIVI_RS14095
uniprot id: I3YCU0
names: Similarity
messages: Belongs to the UPF0178 family.

765911:THIVI RS19020
gene id: 765911:THIVI_RS19020
uniprot id: I3YFK4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS20745
gene id: 765911:THIVI_RS20745
uniprot id: I3YGI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

765911:THIVI RS01780
gene id: 765911:THIVI_RS01780
uniprot id: U3GKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

765911:THIVI RS10175
gene id: 765911:THIVI_RS10175
uniprot id: I3YAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765911:THIVI RS12530
gene id: 765911:THIVI_RS12530
uniprot id: I3YC02
names: Similarity
messages: Belongs to the MoaD family.

765911:THIVI RS08260
gene id: 765911:THIVI_RS08260
uniprot id: I3Y9L4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

765911:THIVI RS18560
gene id: 765911:THIVI_RS18560
uniprot id: I3YFA8
names: Similarity
messages: Belongs to the UPF0250 family.

765911:THIVI RS02720
gene id: 765911:THIVI_RS02720
uniprot id: I3Y6K0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS16325
gene id: 765911:THIVI_RS16325
uniprot id: I3YE19
names: Similarity
messages: Belongs to the peptidase S41A family.

765911:THIVI RS12650
gene id: 765911:THIVI_RS12650
uniprot id: I3YC26
names: Similarity
messages: Belongs to the ArsC family.

765911:THIVI RS01690
gene id: 765911:THIVI_RS01690
uniprot id: I3Y602
names: Similarity
messages: Belongs to the MotB family.

765911:THIVI RS05575
gene id: 765911:THIVI_RS05575
uniprot id: I3Y856
names: Similarity
messages: Belongs to the UPF0045 family.

765911:THIVI RS18120
gene id: 765911:THIVI_RS18120
uniprot id: I3YF23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

765911:THIVI RS03010
gene id: 765911:THIVI_RS03010
uniprot id: I3Y6Q6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

765911:THIVI RS15790
gene id: 765911:THIVI_RS15790
uniprot id: I3YDR4
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

765911:THIVI RS01400
gene id: 765911:THIVI_RS01400
uniprot id: I3Y5U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

765911:THIVI RS20000
gene id: 765911:THIVI_RS20000
uniprot id: I3YG41
names: Similarity
messages: Belongs to the peptidase U62 family.

765911:THIVI RS17360
gene id: 765911:THIVI_RS17360
uniprot id: I3YEM6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

765911:THIVI RS06640
gene id: 765911:THIVI_RS06640
uniprot id: I3Y8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

765911:THIVI RS11795
gene id: 765911:THIVI_RS11795
uniprot id: I3YBK8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

765911:THIVI RS16860
gene id: 765911:THIVI_RS16860
uniprot id: I3YEC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

765911:THIVI RS08960
gene id: 765911:THIVI_RS08960
uniprot id: I3YA04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

765911:THIVI RS06595
gene id: 765911:THIVI_RS06595
uniprot id: I3Y8P9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

765911:THIVI RS16945
gene id: 765911:THIVI_RS16945
uniprot id: I3YEE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

765911:THIVI RS02560
gene id: 765911:THIVI_RS02560
uniprot id: I3Y6G9
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS17225
gene id: 765911:THIVI_RS17225
uniprot id: I3YEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

765911:THIVI RS10280
gene id: 765911:THIVI_RS10280
uniprot id: I3YAR3
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

765911:THIVI RS08485
gene id: 765911:THIVI_RS08485
uniprot id: I3Y9R0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

765911:THIVI RS06670
gene id: 765911:THIVI_RS06670
uniprot id: I3Y8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS01080
gene id: 765911:THIVI_RS01080
uniprot id: I3Y5M4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

765911:THIVI RS01940
gene id: 765911:THIVI_RS01940
uniprot id: I3Y651
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

765911:THIVI RS18360
gene id: 765911:THIVI_RS18360
uniprot id: I3YF69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

765911:THIVI RS06800
gene id: 765911:THIVI_RS06800
uniprot id: I3Y8U3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

765911:THIVI RS05660
gene id: 765911:THIVI_RS05660
uniprot id: I3Y873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

765911:THIVI RS01275
gene id: 765911:THIVI_RS01275
uniprot id: I3Y5R4
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS17785
gene id: 765911:THIVI_RS17785
uniprot id: I3YEV3
names: Subunit
messages: Monomer.

765911:THIVI RS07370
gene id: 765911:THIVI_RS07370
uniprot id: I3Y951
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

765911:THIVI RS08380
gene id: 765911:THIVI_RS08380
uniprot id: I3Y9N8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

765911:THIVI RS15540
gene id: 765911:THIVI_RS15540
uniprot id: I3YDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

765911:THIVI RS21965
gene id: 765911:THIVI_RS21965
uniprot id: I3YH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

765911:THIVI RS05840
gene id: 765911:THIVI_RS05840
uniprot id: I3Y8A4
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS10805
gene id: 765911:THIVI_RS10805
uniprot id: I3YB15
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

765911:THIVI RS01220
gene id: 765911:THIVI_RS01220
uniprot id: I3Y5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

765911:THIVI RS17955
gene id: 765911:THIVI_RS17955
uniprot id: I3YEY7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

765911:THIVI RS16100
gene id: 765911:THIVI_RS16100
uniprot id: I3YDX7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

765911:THIVI RS09570
gene id: 765911:THIVI_RS09570
uniprot id: I3YAB8
names: Similarity
messages: Belongs to the PucC family.

765911:THIVI RS17685
gene id: 765911:THIVI_RS17685
uniprot id: I3YET4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

765911:THIVI RS08305
gene id: 765911:THIVI_RS08305
uniprot id: I3Y9M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

765911:THIVI RS20765
gene id: 765911:THIVI_RS20765
uniprot id: I3YGJ1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

765911:THIVI RS16475
gene id: 765911:THIVI_RS16475
uniprot id: I3YE50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS09590
gene id: 765911:THIVI_RS09590
uniprot id: I3YAC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS09060
gene id: 765911:THIVI_RS09060
uniprot id: I3YA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

765911:THIVI RS11970
gene id: 765911:THIVI_RS11970
uniprot id: I3YBP2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

765911:THIVI RS17330
gene id: 765911:THIVI_RS17330
uniprot id: I3YEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

765911:THIVI RS18570
gene id: 765911:THIVI_RS18570
uniprot id: I3YFB0
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

765911:THIVI RS07380
gene id: 765911:THIVI_RS07380
uniprot id: I3Y953
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS13400
gene id: 765911:THIVI_RS13400
uniprot id: I3YCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

765911:THIVI RS06600
gene id: 765911:THIVI_RS06600
uniprot id: I3Y8Q0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

765911:THIVI RS05370
gene id: 765911:THIVI_RS05370
uniprot id: I3Y816
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

765911:THIVI RS18935
gene id: 765911:THIVI_RS18935
uniprot id: I3YFI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

765911:THIVI RS20325
gene id: 765911:THIVI_RS20325
uniprot id: I3YGA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

765911:THIVI RS01125
gene id: 765911:THIVI_RS01125
uniprot id: I3Y5N3
names: Similarity
messages: Belongs to the UPF0229 family.

765911:THIVI RS08770
gene id: 765911:THIVI_RS08770
uniprot id: I3Y9W5
names: Similarity
messages: Belongs to the Skp family.

765911:THIVI RS02605
gene id: 765911:THIVI_RS02605
uniprot id: I3Y6H8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

765911:THIVI RS16365
gene id: 765911:THIVI_RS16365
uniprot id: I3YE27
names: Similarity
messages: Belongs to the phosphohexose mutase family.

765911:THIVI RS01840
gene id: 765911:THIVI_RS01840
uniprot id: I3Y632
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

765911:THIVI RS15340
gene id: 765911:THIVI_RS15340
uniprot id: I3YDH3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS13180
gene id: 765911:THIVI_RS13180
uniprot id: I3YCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

765911:THIVI RS04910
gene id: 765911:THIVI_RS04910
uniprot id: I3Y7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

765911:THIVI RS20925
gene id: 765911:THIVI_RS20925
uniprot id: I3YGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS02880
gene id: 765911:THIVI_RS02880
uniprot id: I3Y6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

765911:THIVI RS15735
gene id: 765911:THIVI_RS15735
uniprot id: I3YDQ2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

765911:THIVI RS12310
gene id: 765911:THIVI_RS12310
uniprot id: I3YBV9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

765911:THIVI RS03345
gene id: 765911:THIVI_RS03345
uniprot id: I3Y6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS14440
gene id: 765911:THIVI_RS14440
uniprot id: I3YCZ7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

765911:THIVI RS08910
gene id: 765911:THIVI_RS08910
uniprot id: I3Y9Z4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

765911:THIVI RS24225
gene id: 765911:THIVI_RS24225
uniprot id: I3Y7K4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

765911:THIVI RS08525
gene id: 765911:THIVI_RS08525
uniprot id: I3Y9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

765911:THIVI RS15015
gene id: 765911:THIVI_RS15015
uniprot id: I3YDA8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS08040
gene id: 765911:THIVI_RS08040
uniprot id: I3Y9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS20405
gene id: 765911:THIVI_RS20405
uniprot id: I3YGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

765911:THIVI RS01785
gene id: 765911:THIVI_RS01785
uniprot id: U3GJY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

765911:THIVI RS11685
gene id: 765911:THIVI_RS11685
uniprot id: I3YBJ1
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

765911:THIVI RS13950
gene id: 765911:THIVI_RS13950
uniprot id: I3YCR7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS06270
gene id: 765911:THIVI_RS06270
uniprot id: I3Y8J4
names: Similarity
messages: Belongs to the UPF0751 family.

765911:THIVI RS16105
gene id: 765911:THIVI_RS16105
uniprot id: I3YDX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

765911:THIVI RS03095
gene id: 765911:THIVI_RS03095
uniprot id: I3Y6S1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

765911:THIVI RS14860
gene id: 765911:THIVI_RS14860
uniprot id: I3YD77
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

765911:THIVI RS11035
gene id: 765911:THIVI_RS11035
uniprot id: I3YB62
names: Similarity
messages: Belongs to the ClpA/ClpB family.

765911:THIVI RS20235
gene id: 765911:THIVI_RS20235
uniprot id: I3YG83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS05020
gene id: 765911:THIVI_RS05020
uniprot id: I3Y7U2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

765911:THIVI RS14845
gene id: 765911:THIVI_RS14845
uniprot id: I3YD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

765911:THIVI RS20335
gene id: 765911:THIVI_RS20335
uniprot id: I3YGA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

765911:THIVI RS08155
gene id: 765911:THIVI_RS08155
uniprot id: I3Y9J3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

765911:THIVI RS14930
gene id: 765911:THIVI_RS14930
uniprot id: I3YD91
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

765911:THIVI RS03400
gene id: 765911:THIVI_RS03400
uniprot id: I3Y6Y4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

765911:THIVI RS16045
gene id: 765911:THIVI_RS16045
uniprot id: I3YDW6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

765911:THIVI RS14040
gene id: 765911:THIVI_RS14040
uniprot id: I3YCS9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

765911:THIVI RS22150
gene id: 765911:THIVI_RS22150
uniprot id: I3YHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

765911:THIVI RS10260
gene id: 765911:THIVI_RS10260
uniprot id: I3YAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

765911:THIVI RS18875
gene id: 765911:THIVI_RS18875
uniprot id: I3YFH5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

765911:THIVI RS09600
gene id: 765911:THIVI_RS09600
uniprot id: I3YAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS04210
gene id: 765911:THIVI_RS04210
uniprot id: I3Y7C9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

765911:THIVI RS10265
gene id: 765911:THIVI_RS10265
uniprot id: I3YAR0
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

765911:THIVI RS13330
gene id: 765911:THIVI_RS13330
uniprot id: I3YCE3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

765911:THIVI RS06160
gene id: 765911:THIVI_RS06160
uniprot id: I3Y8H3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

765911:THIVI RS01330
gene id: 765911:THIVI_RS01330
uniprot id: I3Y5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS01200
gene id: 765911:THIVI_RS01200
uniprot id: I3Y5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765911:THIVI RS09595
gene id: 765911:THIVI_RS09595
uniprot id: I3YAC6
names: Function
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

765911:THIVI RS00755
gene id: 765911:THIVI_RS00755
uniprot id: I3Y5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

765911:THIVI RS14380
gene id: 765911:THIVI_RS14380
uniprot id: I3YCY4
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS09465
gene id: 765911:THIVI_RS09465
uniprot id: I3YA98
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

765911:THIVI RS18050
gene id: 765911:THIVI_RS18050
uniprot id: I3YF04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

765911:THIVI RS11105
gene id: 765911:THIVI_RS11105
uniprot id: I3YB76
names: Similarity
messages: Belongs to the VgrG protein family.

765911:THIVI RS18895
gene id: 765911:THIVI_RS18895
uniprot id: I3YFH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS17410
gene id: 765911:THIVI_RS17410
uniprot id: I3YEN4
names: Similarity
messages: Belongs to the TrpC family.

765911:THIVI RS16060
gene id: 765911:THIVI_RS16060
uniprot id: I3YDW9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

765911:THIVI RS20240
gene id: 765911:THIVI_RS20240
uniprot id: I3YG84
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

765911:THIVI RS09310
gene id: 765911:THIVI_RS09310
uniprot id: I3YA64
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

765911:THIVI RS04495
gene id: 765911:THIVI_RS04495
uniprot id: I3Y7I8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS02000
gene id: 765911:THIVI_RS02000
uniprot id: I3Y663
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

765911:THIVI RS18085
gene id: 765911:THIVI_RS18085
uniprot id: I3YF16
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

765911:THIVI RS16515
gene id: 765911:THIVI_RS16515
uniprot id: I3YE58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

765911:THIVI RS10050
gene id: 765911:THIVI_RS10050
uniprot id: I3YAL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

765911:THIVI RS11530
gene id: 765911:THIVI_RS11530
uniprot id: I3YBF9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

765911:THIVI RS17745
gene id: 765911:THIVI_RS17745
uniprot id: I3YEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

765911:THIVI RS00360
gene id: 765911:THIVI_RS00360
uniprot id: I3Y590
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS16830
gene id: 765911:THIVI_RS16830
uniprot id: I3YEC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

765911:THIVI RS13515
gene id: 765911:THIVI_RS13515
uniprot id: I3YCI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

765911:THIVI RS20520
gene id: 765911:THIVI_RS20520
uniprot id: I3YGE1
names: Subcellular Location Annotation
messages: Cytoplasm

765911:THIVI RS07265
gene id: 765911:THIVI_RS07265
uniprot id: I3Y933
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS05525
gene id: 765911:THIVI_RS05525
uniprot id: I3Y846
names: Similarity
messages: Belongs to the acylphosphatase family.

765911:THIVI RS01250
gene id: 765911:THIVI_RS01250
uniprot id: I3Y5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS02440
gene id: 765911:THIVI_RS02440
uniprot id: I3Y6E7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

765911:THIVI RS00880
gene id: 765911:THIVI_RS00880
uniprot id: I3Y5I5
names: Similarity
messages: Belongs to the bacterial secretin family.

765911:THIVI RS15440
gene id: 765911:THIVI_RS15440
uniprot id: I3YDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS01440
gene id: 765911:THIVI_RS01440
uniprot id: I3Y5V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

765911:THIVI RS16805
gene id: 765911:THIVI_RS16805
uniprot id: I3YEB6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

765911:THIVI RS20425
gene id: 765911:THIVI_RS20425
uniprot id: I3YGC2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

765911:THIVI RS14230
gene id: 765911:THIVI_RS14230
uniprot id: I3YCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

765911:THIVI RS17035
gene id: 765911:THIVI_RS17035
uniprot id: I3YEG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

765911:THIVI RS15925
gene id: 765911:THIVI_RS15925
uniprot id: I3YDU1
names: Similarity
messages: Belongs to the HesB/IscA family.

765911:THIVI RS20540
gene id: 765911:THIVI_RS20540
uniprot id: I3YGE5
names: Similarity
messages: Belongs to the asparagine synthetase family.

765911:THIVI RS05985
gene id: 765911:THIVI_RS05985
uniprot id: I3Y8D2
names: Similarity
messages: Belongs to the UPF0175 family.

765911:THIVI RS02125
gene id: 765911:THIVI_RS02125
uniprot id: I3Y690
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS20320
gene id: 765911:THIVI_RS20320
uniprot id: I3YGA0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

765911:THIVI RS15625
gene id: 765911:THIVI_RS15625
uniprot id: I3YDN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

765911:THIVI RS00275
gene id: 765911:THIVI_RS00275
uniprot id: I3Y575
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS10250
gene id: 765911:THIVI_RS10250
uniprot id: I3YAQ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

765911:THIVI RS04370
gene id: 765911:THIVI_RS04370
uniprot id: I3Y7G3
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

765911:THIVI RS15560
gene id: 765911:THIVI_RS15560
uniprot id: I3YDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

765911:THIVI RS16555
gene id: 765911:THIVI_RS16555
uniprot id: I3YE67
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS05200
gene id: 765911:THIVI_RS05200
uniprot id: I3Y7X9
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS13285
gene id: 765911:THIVI_RS13285
uniprot id: I3YCD4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

765911:THIVI RS07995
gene id: 765911:THIVI_RS07995
uniprot id: I3Y9G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

765911:THIVI RS22185
gene id: 765911:THIVI_RS22185
uniprot id: I3YHB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

765911:THIVI RS01340
gene id: 765911:THIVI_RS01340
uniprot id: I3Y5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS00110
gene id: 765911:THIVI_RS00110
uniprot id: I3Y542
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

765911:THIVI RS16495
gene id: 765911:THIVI_RS16495
uniprot id: I3YE54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

765911:THIVI RS20050
gene id: 765911:THIVI_RS20050
uniprot id: I3YG50
names: Similarity
messages: Belongs to the SAICAR synthetase family.

765911:THIVI RS10725
gene id: 765911:THIVI_RS10725
uniprot id: I3YB00
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS08220
gene id: 765911:THIVI_RS08220
uniprot id: I3Y9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

765911:THIVI RS10145
gene id: 765911:THIVI_RS10145
uniprot id: I3YAN7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS18180
gene id: 765911:THIVI_RS18180
uniprot id: I3YF34
names: Similarity
messages: Belongs to the peptidase A31 family.

765911:THIVI RS20455
gene id: 765911:THIVI_RS20455
uniprot id: I3YGC8
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

765911:THIVI RS21635
gene id: 765911:THIVI_RS21635
uniprot id: I3YH05
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

765911:THIVI RS12655
gene id: 765911:THIVI_RS12655
uniprot id: I3YC27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

765911:THIVI RS01140
gene id: 765911:THIVI_RS01140
uniprot id: I3Y5N6
names: Similarity
messages: Belongs to the YkuD family.

765911:THIVI RS19310
gene id: 765911:THIVI_RS19310
uniprot id: I3YFR2
names: Cofactor
messages: Can also use Mn(2+) ion.

765911:THIVI RS04505
gene id: 765911:THIVI_RS04505
uniprot id: I3Y7J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

765911:THIVI RS17750
gene id: 765911:THIVI_RS17750
uniprot id: I3YEU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

765911:THIVI RS09645
gene id: 765911:THIVI_RS09645
uniprot id: I3YAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS17085
gene id: 765911:THIVI_RS17085
uniprot id: I3YEH5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765911:THIVI RS12120
gene id: 765911:THIVI_RS12120
uniprot id: I3YBS0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

765911:THIVI RS19805
gene id: 765911:THIVI_RS19805
uniprot id: I3YG01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

765911:THIVI RS12555
gene id: 765911:THIVI_RS12555
uniprot id: I3YC07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

765911:THIVI RS08740
gene id: 765911:THIVI_RS08740
uniprot id: I3Y9V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

765911:THIVI RS08130
gene id: 765911:THIVI_RS08130
uniprot id: I3Y9I8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

765911:THIVI RS12325
gene id: 765911:THIVI_RS12325
uniprot id: I3YBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

765911:THIVI RS10680
gene id: 765911:THIVI_RS10680
uniprot id: I3YAZ1
names: Similarity
messages: Belongs to the MotB family.

765911:THIVI RS13525
gene id: 765911:THIVI_RS13525
uniprot id: I3YCI2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

765911:THIVI RS12140
gene id: 765911:THIVI_RS12140
uniprot id: I3YBS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS05140
gene id: 765911:THIVI_RS05140
uniprot id: I3Y7W6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS01535
gene id: 765911:THIVI_RS01535
uniprot id: I3Y5X0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

765911:THIVI RS16825
gene id: 765911:THIVI_RS16825
uniprot id: I3YEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS08920
gene id: 765911:THIVI_RS08920
uniprot id: I3Y9Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

765911:THIVI RS21030
gene id: 765911:THIVI_RS21030
uniprot id: I3YGP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

765911:THIVI RS01850
gene id: 765911:THIVI_RS01850
uniprot id: I3Y634
names: Similarity
messages: Belongs to the MotB family.

765911:THIVI RS02445
gene id: 765911:THIVI_RS02445
uniprot id: I3Y6E8
names: Similarity
messages: Belongs to the peptidase U62 family.

765911:THIVI RS10695
gene id: 765911:THIVI_RS10695
uniprot id: I3YAZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

765911:THIVI RS01745
gene id: 765911:THIVI_RS01745
uniprot id: I3Y613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS00895
gene id: 765911:THIVI_RS00895
uniprot id: I3Y5I8
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS07555
gene id: 765911:THIVI_RS07555
uniprot id: I3Y985
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

765911:THIVI RS20990
gene id: 765911:THIVI_RS20990
uniprot id: I3YGN5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

765911:THIVI RS02700
gene id: 765911:THIVI_RS02700
uniprot id: I3Y6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

765911:THIVI RS18440
gene id: 765911:THIVI_RS18440
uniprot id: I3YF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765911:THIVI RS13190
gene id: 765911:THIVI_RS13190
uniprot id: I3YCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

765911:THIVI RS08715
gene id: 765911:THIVI_RS08715
uniprot id: I3Y9V3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

765911:THIVI RS03365
gene id: 765911:THIVI_RS03365
uniprot id: U3GKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

765911:THIVI RS00455
gene id: 765911:THIVI_RS00455
uniprot id: I3Y5A9
names: PTM
messages: Binds 1 heme group per subunit.

765911:THIVI RS12290
gene id: 765911:THIVI_RS12290
uniprot id: I3YBV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

765911:THIVI RS02670
gene id: 765911:THIVI_RS02670
uniprot id: I3Y6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

765911:THIVI RS14555
gene id: 765911:THIVI_RS14555
uniprot id: I3YD18
names: Similarity
messages: Belongs to the peptidase M16 family.

765911:THIVI RS13500
gene id: 765911:THIVI_RS13500
uniprot id: I3YCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS06745
gene id: 765911:THIVI_RS06745
uniprot id: I3Y8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

765911:THIVI RS02030
gene id: 765911:THIVI_RS02030
uniprot id: I3Y669
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS00420
gene id: 765911:THIVI_RS00420
uniprot id: I3Y5A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

765911:THIVI RS09780
gene id: 765911:THIVI_RS09780
uniprot id: I3YAG6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

765911:THIVI RS01900
gene id: 765911:THIVI_RS01900
uniprot id: I3Y642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

765911:THIVI RS00090
gene id: 765911:THIVI_RS00090
uniprot id: I3Y538
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

765911:THIVI RS03040
gene id: 765911:THIVI_RS03040
uniprot id: I3Y6R2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

765911:THIVI RS22230
gene id: 765911:THIVI_RS22230
uniprot id: I3YHC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

765911:THIVI RS09380
gene id: 765911:THIVI_RS09380
uniprot id: I3YA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

765911:THIVI RS09365
gene id: 765911:THIVI_RS09365
uniprot id: I3YA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS14775
gene id: 765911:THIVI_RS14775
uniprot id: I3YD58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

765911:THIVI RS11360
gene id: 765911:THIVI_RS11360
uniprot id: I3YBC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

765911:THIVI RS15650
gene id: 765911:THIVI_RS15650
uniprot id: I3YDN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

765911:THIVI RS03975
gene id: 765911:THIVI_RS03975
uniprot id: I3Y787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

765911:THIVI RS02920
gene id: 765911:THIVI_RS02920
uniprot id: I3Y6N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

765911:THIVI RS12510
gene id: 765911:THIVI_RS12510
uniprot id: I3YBZ8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

765911:THIVI RS07550
gene id: 765911:THIVI_RS07550
uniprot id: I3Y984
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

765911:THIVI RS20130
gene id: 765911:THIVI_RS20130
uniprot id: I3YG67
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS13175
gene id: 765911:THIVI_RS13175
uniprot id: I3YCB2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

765911:THIVI RS09340
gene id: 765911:THIVI_RS09340
uniprot id: I3YA70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS13570
gene id: 765911:THIVI_RS13570
uniprot id: I3YCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

765911:THIVI RS14550
gene id: 765911:THIVI_RS14550
uniprot id: I3YD17
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

765911:THIVI RS19770
gene id: 765911:THIVI_RS19770
uniprot id: I3YFZ4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

765911:THIVI RS08995
gene id: 765911:THIVI_RS08995
uniprot id: I3YA10
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

765911:THIVI RS00025
gene id: 765911:THIVI_RS00025
uniprot id: I3Y525
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

765911:THIVI RS18750
gene id: 765911:THIVI_RS18750
uniprot id: I3YFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

765911:THIVI RS06130
gene id: 765911:THIVI_RS06130
uniprot id: I3Y8G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

765911:THIVI RS13095
gene id: 765911:THIVI_RS13095
uniprot id: I3YC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

765911:THIVI RS22330
gene id: 765911:THIVI_RS22330
uniprot id: I3YHE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

765911:THIVI RS15370
gene id: 765911:THIVI_RS15370
uniprot id: I3YDH9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

765911:THIVI RS05580
gene id: 765911:THIVI_RS05580
uniprot id: I3Y857
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

765911:THIVI RS10415
gene id: 765911:THIVI_RS10415
uniprot id: I3YAT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

765911:THIVI RS05685
gene id: 765911:THIVI_RS05685
uniprot id: I3Y878
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS20750
gene id: 765911:THIVI_RS20750
uniprot id: I3YGI8
names: Similarity
messages: Belongs to the NifZ family.

765911:THIVI RS17525
gene id: 765911:THIVI_RS17525
uniprot id: I3YEQ2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

765911:THIVI RS18535
gene id: 765911:THIVI_RS18535
uniprot id: I3YFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

765911:THIVI RS17920
gene id: 765911:THIVI_RS17920
uniprot id: I3YEY0
names: Similarity
messages: Belongs to the HypD family.

765911:THIVI RS14105
gene id: 765911:THIVI_RS14105
uniprot id: I3YCU2
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

765911:THIVI RS21040
gene id: 765911:THIVI_RS21040
uniprot id: I3YGP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

765911:THIVI RS10040
gene id: 765911:THIVI_RS10040
uniprot id: I3YAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

765911:THIVI RS00765
gene id: 765911:THIVI_RS00765
uniprot id: I3Y5G6
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS07595
gene id: 765911:THIVI_RS07595
uniprot id: I3Y992
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

765911:THIVI RS15320
gene id: 765911:THIVI_RS15320
uniprot id: I3YDG9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

765911:THIVI RS02295
gene id: 765911:THIVI_RS02295
uniprot id: I3Y6B8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

765911:THIVI RS09040
gene id: 765911:THIVI_RS09040
uniprot id: I3YA17
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

765911:THIVI RS01565
gene id: 765911:THIVI_RS01565
uniprot id: I3Y5X6
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

765911:THIVI RS16845
gene id: 765911:THIVI_RS16845
uniprot id: I3YEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

765911:THIVI RS03680
gene id: 765911:THIVI_RS03680
uniprot id: I3Y738
names: Caution
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

765911:THIVI RS08930
gene id: 765911:THIVI_RS08930
uniprot id: I3Y9Z8
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

765911:THIVI RS18040
gene id: 765911:THIVI_RS18040
uniprot id: I3YF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

765911:THIVI RS04510
gene id: 765911:THIVI_RS04510
uniprot id: I3Y7J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

765911:THIVI RS15510
gene id: 765911:THIVI_RS15510
uniprot id: I3YDK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

765911:THIVI RS10785
gene id: 765911:THIVI_RS10785
uniprot id: I3YB11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

765911:THIVI RS11980
gene id: 765911:THIVI_RS11980
uniprot id: I3YBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

765911:THIVI RS02965
gene id: 765911:THIVI_RS02965
uniprot id: I3Y6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

765911:THIVI RS16465
gene id: 765911:THIVI_RS16465
uniprot id: I3YE48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

765911:THIVI RS12250
gene id: 765911:THIVI_RS12250
uniprot id: I3YBU6
names: Similarity
messages: Belongs to the ModE family.

765911:THIVI RS11555
gene id: 765911:THIVI_RS11555
uniprot id: I3YBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS18185
gene id: 765911:THIVI_RS18185
uniprot id: I3YF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

765911:THIVI RS10730
gene id: 765911:THIVI_RS10730
uniprot id: I3YB01
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS03055
gene id: 765911:THIVI_RS03055
uniprot id: I3Y6R5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

765911:THIVI RS19920
gene id: 765911:THIVI_RS19920
uniprot id: I3YG24
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

765911:THIVI RS11205
gene id: 765911:THIVI_RS11205
uniprot id: I3YB96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

765911:THIVI RS20370
gene id: 765911:THIVI_RS20370
uniprot id: I3YGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

765911:THIVI RS09100
gene id: 765911:THIVI_RS09100
uniprot id: I3YA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765911:THIVI RS13830
gene id: 765911:THIVI_RS13830
uniprot id: I3YCP4
names: Similarity
messages: Belongs to the citrate synthase family.

765911:THIVI RS15530
gene id: 765911:THIVI_RS15530
uniprot id: I3YDL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

765911:THIVI RS11195
gene id: 765911:THIVI_RS11195
uniprot id: I3YB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

765911:THIVI RS04625
gene id: 765911:THIVI_RS04625
uniprot id: I3Y7L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

765911:THIVI RS20250
gene id: 765911:THIVI_RS20250
uniprot id: I3YG86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

765911:THIVI RS19800
gene id: 765911:THIVI_RS19800
uniprot id: I3YG00
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

765911:THIVI RS19530
gene id: 765911:THIVI_RS19530
uniprot id: I3YFU4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

765911:THIVI RS14130
gene id: 765911:THIVI_RS14130
uniprot id: I3YCU7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS15155
gene id: 765911:THIVI_RS15155
uniprot id: I3YDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

765911:THIVI RS06810
gene id: 765911:THIVI_RS06810
uniprot id: I3Y8U5
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

765911:THIVI RS04535
gene id: 765911:THIVI_RS04535
uniprot id: I3Y7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

765911:THIVI RS15295
gene id: 765911:THIVI_RS15295
uniprot id: I3YDG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

765911:THIVI RS18555
gene id: 765911:THIVI_RS18555
uniprot id: I3YFA7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

765911:THIVI RS20390
gene id: 765911:THIVI_RS20390
uniprot id: I3YGB4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

765911:THIVI RS02130
gene id: 765911:THIVI_RS02130
uniprot id: I3Y691
names: Similarity
messages: Belongs to the peptidase S11 family.

765911:THIVI RS08670
gene id: 765911:THIVI_RS08670
uniprot id: I3Y9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

765911:THIVI RS19015
gene id: 765911:THIVI_RS19015
uniprot id: I3YFK3
names: Similarity
messages: Belongs to the cytochrome c-552 family.

765911:THIVI RS13895
gene id: 765911:THIVI_RS13895
uniprot id: I3YCQ6
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS05295
gene id: 765911:THIVI_RS05295
uniprot id: I3Y800
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

765911:THIVI RS09995
gene id: 765911:THIVI_RS09995
uniprot id: I3YAL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

765911:THIVI RS05670
gene id: 765911:THIVI_RS05670
uniprot id: I3Y875
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

765911:THIVI RS17870
gene id: 765911:THIVI_RS17870
uniprot id: I3YEW9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

765911:THIVI RS10235
gene id: 765911:THIVI_RS10235
uniprot id: I3YAQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765911:THIVI RS02390
gene id: 765911:THIVI_RS02390
uniprot id: I3Y6D7
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS18925
gene id: 765911:THIVI_RS18925
uniprot id: I3YFI4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

765911:THIVI RS09700
gene id: 765911:THIVI_RS09700
uniprot id: I3YAF0
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

765911:THIVI RS18250
gene id: 765911:THIVI_RS18250
uniprot id: I3YF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

765911:THIVI RS12695
gene id: 765911:THIVI_RS12695
uniprot id: I3YC35
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

765911:THIVI RS20885
gene id: 765911:THIVI_RS20885
uniprot id: I3YGL4
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

765911:THIVI RS19175
gene id: 765911:THIVI_RS19175
uniprot id: I3YFN4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

765911:THIVI RS02975
gene id: 765911:THIVI_RS02975
uniprot id: I3Y6P9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

765911:THIVI RS16280
gene id: 765911:THIVI_RS16280
uniprot id: I3YE10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

765911:THIVI RS18190
gene id: 765911:THIVI_RS18190
uniprot id: I3YF36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

765911:THIVI RS08645
gene id: 765911:THIVI_RS08645
uniprot id: I3Y9U0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

765911:THIVI RS19825
gene id: 765911:THIVI_RS19825
uniprot id: I3YG05
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

765911:THIVI RS10780
gene id: 765911:THIVI_RS10780
uniprot id: I3YB10
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

765911:THIVI RS07450
gene id: 765911:THIVI_RS07450
uniprot id: I3Y966
names: Similarity
messages: Belongs to the HsdR family.

765911:THIVI RS16430
gene id: 765911:THIVI_RS16430
uniprot id: I3YE40
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

765911:THIVI RS13380
gene id: 765911:THIVI_RS13380
uniprot id: I3YCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

765911:THIVI RS08080
gene id: 765911:THIVI_RS08080
uniprot id: I3Y9H8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

765911:THIVI RS13420
gene id: 765911:THIVI_RS13420
uniprot id: I3YCG1
names: Similarity
messages: Belongs to the GSP E family.

765911:THIVI RS05695
gene id: 765911:THIVI_RS05695
uniprot id: I3Y880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

765911:THIVI RS09080
gene id: 765911:THIVI_RS09080
uniprot id: I3YA25
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

765911:THIVI RS01915
gene id: 765911:THIVI_RS01915
uniprot id: I3Y646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

765911:THIVI RS11500
gene id: 765911:THIVI_RS11500
uniprot id: I3YBF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

765911:THIVI RS11355
gene id: 765911:THIVI_RS11355
uniprot id: I3YBC5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

765911:THIVI RS15180
gene id: 765911:THIVI_RS15180
uniprot id: I3YDE2
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS10045
gene id: 765911:THIVI_RS10045
uniprot id: I3YAL8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

765911:THIVI RS04790
gene id: 765911:THIVI_RS04790
uniprot id: I3Y7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

765911:THIVI RS21020
gene id: 765911:THIVI_RS21020
uniprot id: I3YGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

765911:THIVI RS10570
gene id: 765911:THIVI_RS10570
uniprot id: I3YAW9
names: Similarity
messages: Belongs to the group II decarboxylase family.

765911:THIVI RS08235
gene id: 765911:THIVI_RS08235
uniprot id: I3Y9K9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

765911:THIVI RS16305
gene id: 765911:THIVI_RS16305
uniprot id: I3YE15
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

765911:THIVI RS01215
gene id: 765911:THIVI_RS01215
uniprot id: I3Y5Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

765911:THIVI RS02675
gene id: 765911:THIVI_RS02675
uniprot id: I3Y6J1
names: Subcellular Location Annotation
messages: Membrane

765911:THIVI RS24220
gene id: 765911:THIVI_RS24220
uniprot id: I3Y7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

765911:THIVI RS16520
gene id: 765911:THIVI_RS16520
uniprot id: I3YE59
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

765911:THIVI RS04760
gene id: 765911:THIVI_RS04760
uniprot id: I3Y7P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

765911:THIVI RS20080
gene id: 765911:THIVI_RS20080
uniprot id: I3YG56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

765911:THIVI RS10820
gene id: 765911:THIVI_RS10820
uniprot id: I3YB19
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

765911:THIVI RS18840
gene id: 765911:THIVI_RS18840
uniprot id: I3YFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

765911:THIVI RS13395
gene id: 765911:THIVI_RS13395
uniprot id: I3YCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.