765177:DESMU RS00470
gene id: 765177:DESMU_RS00470
uniprot id: E8RAJ7
names: Similarity
messages: Belongs to the UPF0216 family.

765177:DESMU RS06890
gene id: 765177:DESMU_RS06890
uniprot id: E8R7I0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

765177:DESMU RS04280
gene id: 765177:DESMU_RS04280
uniprot id: E8R9H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

765177:DESMU RS06830
gene id: 765177:DESMU_RS06830
uniprot id: E8R7G8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.

765177:DESMU RS04845
gene id: 765177:DESMU_RS04845
uniprot id: E8R9T5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

765177:DESMU RS04155
gene id: 765177:DESMU_RS04155
uniprot id: E8R9E9
names: Similarity
messages: Belongs to the HypE family.

765177:DESMU RS00040
gene id: 765177:DESMU_RS00040
uniprot id: E8RA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS06110
gene id: 765177:DESMU_RS06110
uniprot id: E8RAR2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

765177:DESMU RS06655
gene id: 765177:DESMU_RS06655
uniprot id: E8R7D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

765177:DESMU RS05930
gene id: 765177:DESMU_RS05930
uniprot id: E8RAM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS01795
gene id: 765177:DESMU_RS01795
uniprot id: E8R839
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

765177:DESMU RS06945
gene id: 765177:DESMU_RS06945
uniprot id: E8R7R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

765177:DESMU RS00525
gene id: 765177:DESMU_RS00525
uniprot id: E8R6Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS01385
gene id: 765177:DESMU_RS01385
uniprot id: E8R7V7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

765177:DESMU RS00970
gene id: 765177:DESMU_RS00970
uniprot id: E8R7K9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

765177:DESMU RS05115
gene id: 765177:DESMU_RS05115
uniprot id: E8R9Y9
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS02925
gene id: 765177:DESMU_RS02925
uniprot id: E8R8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

765177:DESMU RS06290
gene id: 765177:DESMU_RS06290
uniprot id: E8R768
names: Similarity
messages: Belongs to the pyruvate kinase family.

765177:DESMU RS02770
gene id: 765177:DESMU_RS02770
uniprot id: E8R8M7
names: Similarity
messages: Belongs to the HypE family.

765177:DESMU RS01155
gene id: 765177:DESMU_RS01155
uniprot id: E8R7P4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS06065
gene id: 765177:DESMU_RS06065
uniprot id: E8RAQ3
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS06730
gene id: 765177:DESMU_RS06730
uniprot id: E8R7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

765177:DESMU RS04440
gene id: 765177:DESMU_RS04440
uniprot id: E8R9K5
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

765177:DESMU RS06080
gene id: 765177:DESMU_RS06080
uniprot id: E8RAQ7
names: Subcellular Location Annotation
messages: Nucleus

765177:DESMU RS04970
gene id: 765177:DESMU_RS04970
uniprot id: E8R9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

765177:DESMU RS04640
gene id: 765177:DESMU_RS04640
uniprot id: E8R9P3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

765177:DESMU RS06960
gene id: 765177:DESMU_RS06960
uniprot id: E8R7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

765177:DESMU RS01260
gene id: 765177:DESMU_RS01260
uniprot id: E8R7T3
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

765177:DESMU RS01405
gene id: 765177:DESMU_RS01405
uniprot id: E8R7W1
names: Similarity
messages: Belongs to the peptidase U62 family.

765177:DESMU RS06370
gene id: 765177:DESMU_RS06370
uniprot id: E8R783
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

765177:DESMU RS00780
gene id: 765177:DESMU_RS00780
uniprot id: E8R734
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

765177:DESMU RS06700
gene id: 765177:DESMU_RS06700
uniprot id: E8R7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

765177:DESMU RS05080
gene id: 765177:DESMU_RS05080
uniprot id: E8R9Y2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS06530
gene id: 765177:DESMU_RS06530
uniprot id: E8R7B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

765177:DESMU RS01555
gene id: 765177:DESMU_RS01555
uniprot id: E8R7Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS06515
gene id: 765177:DESMU_RS06515
uniprot id: E8R7B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

765177:DESMU RS04470
gene id: 765177:DESMU_RS04470
uniprot id: E8R9L2
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06495
gene id: 765177:DESMU_RS06495
uniprot id: E8R7A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS04755
gene id: 765177:DESMU_RS04755
uniprot id: E8R9R7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

765177:DESMU RS06920
gene id: 765177:DESMU_RS06920
uniprot id: E8R7Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

765177:DESMU RS00610
gene id: 765177:DESMU_RS00610
uniprot id: E8R700
names: Similarity
messages: Belongs to the AOR/FOR family.

765177:DESMU RS03135
gene id: 765177:DESMU_RS03135
uniprot id: E8R8U8
names: Similarity
messages: Belongs to the AOR/FOR family.

765177:DESMU RS01660
gene id: 765177:DESMU_RS01660
uniprot id: E8R812
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS06950
gene id: 765177:DESMU_RS06950
uniprot id: E8R7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

765177:DESMU RS00575
gene id: 765177:DESMU_RS00575
uniprot id: E8R6Z4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

765177:DESMU RS01535
gene id: 765177:DESMU_RS01535
uniprot id: E8R7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

765177:DESMU RS05670
gene id: 765177:DESMU_RS05670
uniprot id: E8RAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

765177:DESMU RS06705
gene id: 765177:DESMU_RS06705
uniprot id: E8R7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

765177:DESMU RS05600
gene id: 765177:DESMU_RS05600
uniprot id: E8RA97
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

765177:DESMU RS05975
gene id: 765177:DESMU_RS05975
uniprot id: E8RAN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

765177:DESMU RS02580
gene id: 765177:DESMU_RS02580
uniprot id: E8R8J0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

765177:DESMU RS02990
gene id: 765177:DESMU_RS02990
uniprot id: E8R8S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

765177:DESMU RS01900
gene id: 765177:DESMU_RS01900
uniprot id: E8R861
names: Similarity
messages: Belongs to the DtxR/MntR family.

765177:DESMU RS00165
gene id: 765177:DESMU_RS00165
uniprot id: E8RAE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

765177:DESMU RS01550
gene id: 765177:DESMU_RS01550
uniprot id: E8R7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

765177:DESMU RS00890
gene id: 765177:DESMU_RS00890
uniprot id: E8R7J3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

765177:DESMU RS01265
gene id: 765177:DESMU_RS01265
uniprot id: E8R7T4
names: Similarity
messages: Belongs to the UPF0273 family.

765177:DESMU RS00540
gene id: 765177:DESMU_RS00540
uniprot id: E8R6Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS04095
gene id: 765177:DESMU_RS04095
uniprot id: E8R9D7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS02815
gene id: 765177:DESMU_RS02815
uniprot id: E8R8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS03370
gene id: 765177:DESMU_RS03370
uniprot id: E8R8Z4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

765177:DESMU RS02375
gene id: 765177:DESMU_RS02375
uniprot id: E8R8E8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

765177:DESMU RS02900
gene id: 765177:DESMU_RS02900
uniprot id: E8R8Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

765177:DESMU RS03755
gene id: 765177:DESMU_RS03755
uniprot id: E8R972
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

765177:DESMU RS06600
gene id: 765177:DESMU_RS06600
uniprot id: E8R7C5
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00010
gene id: 765177:DESMU_RS00010
uniprot id: E8RA43
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

765177:DESMU RS01170
gene id: 765177:DESMU_RS01170
uniprot id: E8R7P6
names: Similarity
messages: Belongs to the BtpA family.

765177:DESMU RS06860
gene id: 765177:DESMU_RS06860
uniprot id: E8R7H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

765177:DESMU RS05360
gene id: 765177:DESMU_RS05360
uniprot id: E8RA31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

765177:DESMU RS01850
gene id: 765177:DESMU_RS01850
uniprot id: E8R850
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

765177:DESMU RS06745
gene id: 765177:DESMU_RS06745
uniprot id: E8R7F1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

765177:DESMU RS03085
gene id: 765177:DESMU_RS03085
uniprot id: E8R8T8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

765177:DESMU RS04720
gene id: 765177:DESMU_RS04720
uniprot id: E8R9R0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

765177:DESMU RS03000
gene id: 765177:DESMU_RS03000
uniprot id: E8R8S2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

765177:DESMU RS06795
gene id: 765177:DESMU_RS06795
uniprot id: E8R7G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

765177:DESMU RS04995
gene id: 765177:DESMU_RS04995
uniprot id: E8R9W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

765177:DESMU RS03355
gene id: 765177:DESMU_RS03355
uniprot id: E8R8Z1
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

765177:DESMU RS06140
gene id: 765177:DESMU_RS06140
uniprot id: E8RAR9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS03465
gene id: 765177:DESMU_RS03465
uniprot id: E8R913
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

765177:DESMU RS05020
gene id: 765177:DESMU_RS05020
uniprot id: E8R9X0
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

765177:DESMU RS06845
gene id: 765177:DESMU_RS06845
uniprot id: E8R7H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

765177:DESMU RS04425
gene id: 765177:DESMU_RS04425
uniprot id: E8R9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

765177:DESMU RS05915
gene id: 765177:DESMU_RS05915
uniprot id: E8RAM3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

765177:DESMU RS02780
gene id: 765177:DESMU_RS02780
uniprot id: E8R8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

765177:DESMU RS05620
gene id: 765177:DESMU_RS05620
uniprot id: E8RAA1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00030
gene id: 765177:DESMU_RS00030
uniprot id: E8RA46
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

765177:DESMU RS00110
gene id: 765177:DESMU_RS00110
uniprot id: E8RAD0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

765177:DESMU RS05940
gene id: 765177:DESMU_RS05940
uniprot id: E8RAM8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

765177:DESMU RS04060
gene id: 765177:DESMU_RS04060
uniprot id: E8R9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS01425
gene id: 765177:DESMU_RS01425
uniprot id: E8R7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

765177:DESMU RS03280
gene id: 765177:DESMU_RS03280
uniprot id: E8R8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

765177:DESMU RS01195
gene id: 765177:DESMU_RS01195
uniprot id: E8R7Q1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

765177:DESMU RS02935
gene id: 765177:DESMU_RS02935
uniprot id: E8R8R0
names: Subcellular Location Annotation
messages: Nucleus

765177:DESMU RS05950
gene id: 765177:DESMU_RS05950
uniprot id: E8RAN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

765177:DESMU RS06350
gene id: 765177:DESMU_RS06350
uniprot id: E8R779
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS00155
gene id: 765177:DESMU_RS00155
uniprot id: E8RAD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

765177:DESMU RS01225
gene id: 765177:DESMU_RS01225
uniprot id: E8R7S6
names: Similarity
messages: Belongs to the UPF0111 family.

765177:DESMU RS06230
gene id: 765177:DESMU_RS06230
uniprot id: E8R758
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

765177:DESMU RS03670
gene id: 765177:DESMU_RS03670
uniprot id: E8R955
names: Subunit
messages: Homodimer.

765177:DESMU RS06155
gene id: 765177:DESMU_RS06155
uniprot id: E8R743
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05585
gene id: 765177:DESMU_RS05585
uniprot id: E8RA94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

765177:DESMU RS05995
gene id: 765177:DESMU_RS05995
uniprot id: E8RAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

765177:DESMU RS02060
gene id: 765177:DESMU_RS02060
uniprot id: E8R894
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer composed of an alpha and a beta subunit.
messages: Heterodimer of the IorA and IorB subunits.

765177:DESMU RS01635
gene id: 765177:DESMU_RS01635
uniprot id: E8R807
names: Similarity
messages: Belongs to the phosphohexose mutase family.

765177:DESMU RS00645
gene id: 765177:DESMU_RS00645
uniprot id: E8R707
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

765177:DESMU RS05870
gene id: 765177:DESMU_RS05870
uniprot id: E8RAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

765177:DESMU RS04545
gene id: 765177:DESMU_RS04545
uniprot id: E8R9M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

765177:DESMU RS00685
gene id: 765177:DESMU_RS00685
uniprot id: E8R715
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS02645
gene id: 765177:DESMU_RS02645
uniprot id: E8R8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS05190
gene id: 765177:DESMU_RS05190
uniprot id: E8RA00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

765177:DESMU RS01655
gene id: 765177:DESMU_RS01655
uniprot id: E8R811
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS00690
gene id: 765177:DESMU_RS00690
uniprot id: E8R716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

765177:DESMU RS06870
gene id: 765177:DESMU_RS06870
uniprot id: E8R7H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS06765
gene id: 765177:DESMU_RS06765
uniprot id: E8R7F5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

765177:DESMU RS00090
gene id: 765177:DESMU_RS00090
uniprot id: E8RA58
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS01350
gene id: 765177:DESMU_RS01350
uniprot id: E8R7V0
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

765177:DESMU RS04855
gene id: 765177:DESMU_RS04855
uniprot id: E8R9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS05675
gene id: 765177:DESMU_RS05675
uniprot id: E8RAB1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

765177:DESMU RS03630
gene id: 765177:DESMU_RS03630
uniprot id: E8R946
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

765177:DESMU RS01355
gene id: 765177:DESMU_RS01355
uniprot id: E8R7V1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS02540
gene id: 765177:DESMU_RS02540
uniprot id: E8R8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS01530
gene id: 765177:DESMU_RS01530
uniprot id: E8R7Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

765177:DESMU RS03155
gene id: 765177:DESMU_RS03155
uniprot id: E8R8V2
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06420
gene id: 765177:DESMU_RS06420
uniprot id: E8R792
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

765177:DESMU RS06385
gene id: 765177:DESMU_RS06385
uniprot id: E8R786
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

765177:DESMU RS00435
gene id: 765177:DESMU_RS00435
uniprot id: E8RAJ0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

765177:DESMU RS06510
gene id: 765177:DESMU_RS06510
uniprot id: E8R7A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

765177:DESMU RS05810
gene id: 765177:DESMU_RS05810
uniprot id: E8RAK5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

765177:DESMU RS00735
gene id: 765177:DESMU_RS00735
uniprot id: E8R725
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

765177:DESMU RS06005
gene id: 765177:DESMU_RS06005
uniprot id: E8RAP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS02760
gene id: 765177:DESMU_RS02760
uniprot id: E8R8M5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

765177:DESMU RS04260
gene id: 765177:DESMU_RS04260
uniprot id: E8R9G9
names: Similarity
messages: Belongs to the AAA ATPase family.

765177:DESMU RS05120
gene id: 765177:DESMU_RS05120
uniprot id: E8R9Z0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

765177:DESMU RS00535
gene id: 765177:DESMU_RS00535
uniprot id: E8R6Y8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS06790
gene id: 765177:DESMU_RS06790
uniprot id: E8R7G0
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

765177:DESMU RS04735
gene id: 765177:DESMU_RS04735
uniprot id: E8R9R3
names: Similarity
messages: Belongs to the hemerythrin family.

765177:DESMU RS03825
gene id: 765177:DESMU_RS03825
uniprot id: E8R986
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

765177:DESMU RS05690
gene id: 765177:DESMU_RS05690
uniprot id: E8RAB4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

765177:DESMU RS02640
gene id: 765177:DESMU_RS02640
uniprot id: E8R8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS05895
gene id: 765177:DESMU_RS05895
uniprot id: E8RAL9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS04500
gene id: 765177:DESMU_RS04500
uniprot id: E8R9L8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765177:DESMU RS02610
gene id: 765177:DESMU_RS02610
uniprot id: E8R8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS03490
gene id: 765177:DESMU_RS03490
uniprot id: E8R918
names: Similarity
messages: Belongs to the band 7/mec-2 family.

765177:DESMU RS06260
gene id: 765177:DESMU_RS06260
uniprot id: E8R763
names: Similarity
messages: Belongs to the UPF0173 family.

765177:DESMU RS01880
gene id: 765177:DESMU_RS01880
uniprot id: E8R857
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06940
gene id: 765177:DESMU_RS06940
uniprot id: E8R7R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS06265
gene id: 765177:DESMU_RS06265
uniprot id: E8R764
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

765177:DESMU RS01490
gene id: 765177:DESMU_RS01490
uniprot id: E8R7X8
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05920
gene id: 765177:DESMU_RS05920
uniprot id: E8RAM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

765177:DESMU RS00235
gene id: 765177:DESMU_RS00235
uniprot id: E8RAF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

765177:DESMU RS02885
gene id: 765177:DESMU_RS02885
uniprot id: E8R8Q0
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

765177:DESMU RS00745
gene id: 765177:DESMU_RS00745
uniprot id: E8R727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

765177:DESMU RS06955
gene id: 765177:DESMU_RS06955
uniprot id: E8R7R3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

765177:DESMU RS00530
gene id: 765177:DESMU_RS00530
uniprot id: E8R6Y7
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05605
gene id: 765177:DESMU_RS05605
uniprot id: E8RA98
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

765177:DESMU RS02895
gene id: 765177:DESMU_RS02895
uniprot id: E8R8Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

765177:DESMU RS01190
gene id: 765177:DESMU_RS01190
uniprot id: E8R7Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS00255
gene id: 765177:DESMU_RS00255
uniprot id: E8RAF7
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

765177:DESMU RS04410
gene id: 765177:DESMU_RS04410
uniprot id: E8R9J9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

765177:DESMU RS05010
gene id: 765177:DESMU_RS05010
uniprot id: E8R9W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

765177:DESMU RS01820
gene id: 765177:DESMU_RS01820
uniprot id: E8R844
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

765177:DESMU RS03445
gene id: 765177:DESMU_RS03445
uniprot id: E8R909
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

765177:DESMU RS03645
gene id: 765177:DESMU_RS03645
uniprot id: E8R950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765177:DESMU RS00825
gene id: 765177:DESMU_RS00825
uniprot id: E8R7I1
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

765177:DESMU RS02870
gene id: 765177:DESMU_RS02870
uniprot id: E8R8P7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS05820
gene id: 765177:DESMU_RS05820
uniprot id: E8RAK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

765177:DESMU RS05550
gene id: 765177:DESMU_RS05550
uniprot id: E8RA87
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

765177:DESMU RS06800
gene id: 765177:DESMU_RS06800
uniprot id: E8R7G2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS05905
gene id: 765177:DESMU_RS05905
uniprot id: E8RAM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

765177:DESMU RS02600
gene id: 765177:DESMU_RS02600
uniprot id: E8R8J4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

765177:DESMU RS05100
gene id: 765177:DESMU_RS05100
uniprot id: E8R9Y6
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS04495
gene id: 765177:DESMU_RS04495
uniprot id: E8R9L7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

765177:DESMU RS06500
gene id: 765177:DESMU_RS06500
uniprot id: E8R7A7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

765177:DESMU RS06480
gene id: 765177:DESMU_RS06480
uniprot id: E8R7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

765177:DESMU RS04580
gene id: 765177:DESMU_RS04580
uniprot id: E8R9N3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

765177:DESMU RS05635
gene id: 765177:DESMU_RS05635
uniprot id: E8RAA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

765177:DESMU RS03130
gene id: 765177:DESMU_RS03130
uniprot id: E8R8U7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

765177:DESMU RS00600
gene id: 765177:DESMU_RS00600
uniprot id: E8R6Z8
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.

765177:DESMU RS05345
gene id: 765177:DESMU_RS05345
uniprot id: E8RA28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

765177:DESMU RS02940
gene id: 765177:DESMU_RS02940
uniprot id: E8R8R1
names: Similarity
messages: Belongs to the MCM family.

765177:DESMU RS05815
gene id: 765177:DESMU_RS05815
uniprot id: E8RAK6
names: Similarity
messages: Belongs to the peptidase S8 family.

765177:DESMU RS00145
gene id: 765177:DESMU_RS00145
uniprot id: E8RAD7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

765177:DESMU RS06055
gene id: 765177:DESMU_RS06055
uniprot id: E8RAQ1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

765177:DESMU RS02355
gene id: 765177:DESMU_RS02355
uniprot id: E8R8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

765177:DESMU RS05875
gene id: 765177:DESMU_RS05875
uniprot id: E8RAL5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

765177:DESMU RS03700
gene id: 765177:DESMU_RS03700
uniprot id: E8R961
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

765177:DESMU RS06425
gene id: 765177:DESMU_RS06425
uniprot id: E8R793
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

765177:DESMU RS02325
gene id: 765177:DESMU_RS02325
uniprot id: E8R8D9
names: Similarity
messages: Belongs to the acylphosphatase family.

765177:DESMU RS05665
gene id: 765177:DESMU_RS05665
uniprot id: E8RAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

765177:DESMU RS04505
gene id: 765177:DESMU_RS04505
uniprot id: E8R9L9
names: Similarity
messages: Belongs to the UPF0047 family.

765177:DESMU RS01740
gene id: 765177:DESMU_RS01740
uniprot id: E8R828
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

765177:DESMU RS06935
gene id: 765177:DESMU_RS06935
uniprot id: E8R7Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

765177:DESMU RS03685
gene id: 765177:DESMU_RS03685
uniprot id: E8R958
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

765177:DESMU RS04585
gene id: 765177:DESMU_RS04585
uniprot id: E8R9N4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

765177:DESMU RS01815
gene id: 765177:DESMU_RS01815
uniprot id: E8R843
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765177:DESMU RS00050
gene id: 765177:DESMU_RS00050
uniprot id: E8RA50
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

765177:DESMU RS02500
gene id: 765177:DESMU_RS02500
uniprot id: E8R8H4
names: Similarity
messages: Belongs to the HypD family.

765177:DESMU RS03330
gene id: 765177:DESMU_RS03330
uniprot id: E8R8Y6
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00205
gene id: 765177:DESMU_RS00205
uniprot id: E8RAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

765177:DESMU RS06120
gene id: 765177:DESMU_RS06120
uniprot id: E8RAR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

765177:DESMU RS00770
gene id: 765177:DESMU_RS00770
uniprot id: E8R732
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

765177:DESMU RS00595
gene id: 765177:DESMU_RS00595
uniprot id: E8R6Z7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

765177:DESMU RS01725
gene id: 765177:DESMU_RS01725
uniprot id: E8R825
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS05805
gene id: 765177:DESMU_RS05805
uniprot id: E8RAK4
names: Similarity
messages: Belongs to the archease family.

765177:DESMU RS00415
gene id: 765177:DESMU_RS00415
uniprot id: E8RAI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

765177:DESMU RS05740
gene id: 765177:DESMU_RS05740
uniprot id: E8RAC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS06805
gene id: 765177:DESMU_RS06805
uniprot id: E8R7G3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

765177:DESMU RS06720
gene id: 765177:DESMU_RS06720
uniprot id: E8R7E7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

765177:DESMU RS05495
gene id: 765177:DESMU_RS05495
uniprot id: E8RA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

765177:DESMU RS04730
gene id: 765177:DESMU_RS04730
uniprot id: E8R9R2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

765177:DESMU RS01885
gene id: 765177:DESMU_RS01885
uniprot id: E8R858
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS01000
gene id: 765177:DESMU_RS01000
uniprot id: E8R7L5
names: Similarity
messages: Belongs to the RuvB family.

765177:DESMU RS03220
gene id: 765177:DESMU_RS03220
uniprot id: E8R8W5
names: Similarity
messages: Belongs to the UPF0282 family.

765177:DESMU RS04860
gene id: 765177:DESMU_RS04860
uniprot id: E8R9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS05510
gene id: 765177:DESMU_RS05510
uniprot id: E8RA81
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

765177:DESMU RS01905
gene id: 765177:DESMU_RS01905
uniprot id: E8R862
names: Similarity
messages: Belongs to the glutaredoxin family.

765177:DESMU RS02730
gene id: 765177:DESMU_RS02730
uniprot id: E8R8L9
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

765177:DESMU RS04265
gene id: 765177:DESMU_RS04265
uniprot id: E8R9H0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

765177:DESMU RS00875
gene id: 765177:DESMU_RS00875
uniprot id: E8R7J0
names: Similarity
messages: Belongs to the glutamine synthetase family.

765177:DESMU RS05005
gene id: 765177:DESMU_RS05005
uniprot id: E8R9W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

765177:DESMU RS06325
gene id: 765177:DESMU_RS06325
uniprot id: E8R774
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

765177:DESMU RS01875
gene id: 765177:DESMU_RS01875
uniprot id: E8R856
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05355
gene id: 765177:DESMU_RS05355
uniprot id: E8RA30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

765177:DESMU RS04035
gene id: 765177:DESMU_RS04035
uniprot id: E8R9C5
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

765177:DESMU RS04385
gene id: 765177:DESMU_RS04385
uniprot id: E8R9J4
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

765177:DESMU RS00095
gene id: 765177:DESMU_RS00095
uniprot id: E8RA59
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS02200
gene id: 765177:DESMU_RS02200
uniprot id: E8R8C0
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00940
gene id: 765177:DESMU_RS00940
uniprot id: E8R7K3
names: Similarity
messages: Belongs to the HypE family.

765177:DESMU RS05520
gene id: 765177:DESMU_RS05520
uniprot id: E8RA83
names: Similarity
messages: Belongs to the UPF0251 family.

765177:DESMU RS04140
gene id: 765177:DESMU_RS04140
uniprot id: E8R9E6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

765177:DESMU RS04120
gene id: 765177:DESMU_RS04120
uniprot id: E8R9E2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS03180
gene id: 765177:DESMU_RS03180
uniprot id: E8R8V7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

765177:DESMU RS06010
gene id: 765177:DESMU_RS06010
uniprot id: E8RAP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

765177:DESMU RS02560
gene id: 765177:DESMU_RS02560
uniprot id: E8R8I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

765177:DESMU RS01715
gene id: 765177:DESMU_RS01715
uniprot id: E8R823
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

765177:DESMU RS03010
gene id: 765177:DESMU_RS03010
uniprot id: E8R8S4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

765177:DESMU RS04105
gene id: 765177:DESMU_RS04105
uniprot id: E8R9D9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS01345
gene id: 765177:DESMU_RS01345
uniprot id: E8R7U9
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05275
gene id: 765177:DESMU_RS05275
uniprot id: E8RA16
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

765177:DESMU RS06815
gene id: 765177:DESMU_RS06815
uniprot id: E8R7G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

765177:DESMU RS04170
gene id: 765177:DESMU_RS04170
uniprot id: E8R9F2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS03785
gene id: 765177:DESMU_RS03785
uniprot id: E8R978
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

765177:DESMU RS05680
gene id: 765177:DESMU_RS05680
uniprot id: E8RAB2
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

765177:DESMU RS05320
gene id: 765177:DESMU_RS05320
uniprot id: E8RA25
names: Similarity
messages: Belongs to the MoaB/Mog family.

765177:DESMU RS05105
gene id: 765177:DESMU_RS05105
uniprot id: E8R9Y7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS06075
gene id: 765177:DESMU_RS06075
uniprot id: E8RAQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

765177:DESMU RS01255
gene id: 765177:DESMU_RS01255
uniprot id: E8R7T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

765177:DESMU RS05250
gene id: 765177:DESMU_RS05250
uniprot id: E8RA11
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS01185
gene id: 765177:DESMU_RS01185
uniprot id: E8R7P9
names: Similarity
messages: Belongs to the SUI1 family.

765177:DESMU RS03320
gene id: 765177:DESMU_RS03320
uniprot id: E8R8Y4
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05890
gene id: 765177:DESMU_RS05890
uniprot id: E8RAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS05285
gene id: 765177:DESMU_RS05285
uniprot id: E8RA18
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

765177:DESMU RS06630
gene id: 765177:DESMU_RS06630
uniprot id: E8R7D1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05865
gene id: 765177:DESMU_RS05865
uniprot id: E8RAL3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

765177:DESMU RS06475
gene id: 765177:DESMU_RS06475
uniprot id: E8R7A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS03405
gene id: 765177:DESMU_RS03405
uniprot id: E8R901
names: Similarity
messages: Belongs to the UPF0252 family.

765177:DESMU RS04780
gene id: 765177:DESMU_RS04780
uniprot id: E8R9S2
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

765177:DESMU RS06060
gene id: 765177:DESMU_RS06060
uniprot id: E8RAQ2
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS00330
gene id: 765177:DESMU_RS00330
uniprot id: E8RAH2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

765177:DESMU RS06455
gene id: 765177:DESMU_RS06455
uniprot id: E8R799
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

765177:DESMU RS00085
gene id: 765177:DESMU_RS00085
uniprot id: E8RA57
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

765177:DESMU RS04110
gene id: 765177:DESMU_RS04110
uniprot id: E8R9E0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS02975
gene id: 765177:DESMU_RS02975
uniprot id: E8R8R7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

765177:DESMU RS05500
gene id: 765177:DESMU_RS05500
uniprot id: E8RA79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

765177:DESMU RS02290
gene id: 765177:DESMU_RS02290
uniprot id: E8R8D4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS04690
gene id: 765177:DESMU_RS04690
uniprot id: E8R9Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

765177:DESMU RS03090
gene id: 765177:DESMU_RS03090
uniprot id: E8R8T9
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS03935
gene id: 765177:DESMU_RS03935
uniprot id: E8R9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

765177:DESMU RS01935
gene id: 765177:DESMU_RS01935
uniprot id: E8R868
names: Similarity
messages: Belongs to the UPF0111 family.

765177:DESMU RS05925
gene id: 765177:DESMU_RS05925
uniprot id: E8RAM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS01115
gene id: 765177:DESMU_RS01115
uniprot id: E8R7N8
names: Similarity
messages: Belongs to the PstS family.

765177:DESMU RS04370
gene id: 765177:DESMU_RS04370
uniprot id: E8R9J1
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

765177:DESMU RS06985
gene id: 765177:DESMU_RS06985
uniprot id: E8R7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS03260
gene id: 765177:DESMU_RS03260
uniprot id: E8R8X3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

765177:DESMU RS05955
gene id: 765177:DESMU_RS05955
uniprot id: E8RAN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS06255
gene id: 765177:DESMU_RS06255
uniprot id: E8R762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

765177:DESMU RS01685
gene id: 765177:DESMU_RS01685
uniprot id: E8R817
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00175
gene id: 765177:DESMU_RS00175
uniprot id: E8RAE3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

765177:DESMU RS00460
gene id: 765177:DESMU_RS00460
uniprot id: E8RAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

765177:DESMU RS05935
gene id: 765177:DESMU_RS05935
uniprot id: E8RAM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

765177:DESMU RS00865
gene id: 765177:DESMU_RS00865
uniprot id: E8R7I8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

765177:DESMU RS00790
gene id: 765177:DESMU_RS00790
uniprot id: E8R736
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

765177:DESMU RS03690
gene id: 765177:DESMU_RS03690
uniprot id: E8R959
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

765177:DESMU RS06965
gene id: 765177:DESMU_RS06965
uniprot id: E8R7R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS01620
gene id: 765177:DESMU_RS01620
uniprot id: E8R804
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06710
gene id: 765177:DESMU_RS06710
uniprot id: E8R7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

765177:DESMU RS04630
gene id: 765177:DESMU_RS04630
uniprot id: E8R9P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS04080
gene id: 765177:DESMU_RS04080
uniprot id: E8R9D4
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05645
gene id: 765177:DESMU_RS05645
uniprot id: E8RAA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

765177:DESMU RS02415
gene id: 765177:DESMU_RS02415
uniprot id: E8R8F7
names: Similarity
messages: Belongs to the HerA family.

765177:DESMU RS04100
gene id: 765177:DESMU_RS04100
uniprot id: E8R9D8
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS02985
gene id: 765177:DESMU_RS02985
uniprot id: E8R8R9
names: Similarity
messages: Belongs to the UPF0201 family.

765177:DESMU RS06610
gene id: 765177:DESMU_RS06610
uniprot id: E8R7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS04055
gene id: 765177:DESMU_RS04055
uniprot id: E8R9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS03510
gene id: 765177:DESMU_RS03510
uniprot id: E8R921
names: Similarity
messages: Belongs to the UPF0147 family.

765177:DESMU RS01640
gene id: 765177:DESMU_RS01640
uniprot id: E8R808
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

765177:DESMU RS06715
gene id: 765177:DESMU_RS06715
uniprot id: E8R7E6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

765177:DESMU RS05535
gene id: 765177:DESMU_RS05535
uniprot id: E8RA85
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05640
gene id: 765177:DESMU_RS05640
uniprot id: E8RAA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

765177:DESMU RS02030
gene id: 765177:DESMU_RS02030
uniprot id: E8R888
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05970
gene id: 765177:DESMU_RS05970
uniprot id: E8RAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS00475
gene id: 765177:DESMU_RS00475
uniprot id: E8RAJ8
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

765177:DESMU RS06520
gene id: 765177:DESMU_RS06520
uniprot id: E8R7B1
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

765177:DESMU RS03375
gene id: 765177:DESMU_RS03375
uniprot id: E8R8Z5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

765177:DESMU RS04815
gene id: 765177:DESMU_RS04815
uniprot id: E8R9S9
names: Similarity
messages: Belongs to the ZPR1 family.

765177:DESMU RS06525
gene id: 765177:DESMU_RS06525
uniprot id: E8R7B2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

765177:DESMU RS05260
gene id: 765177:DESMU_RS05260
uniprot id: E8RA13
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

765177:DESMU RS06305
gene id: 765177:DESMU_RS06305
uniprot id: E8R770
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

765177:DESMU RS05885
gene id: 765177:DESMU_RS05885
uniprot id: E8RAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

765177:DESMU RS05650
gene id: 765177:DESMU_RS05650
uniprot id: E8RAA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

765177:DESMU RS06490
gene id: 765177:DESMU_RS06490
uniprot id: E8R7A5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

765177:DESMU RS05800
gene id: 765177:DESMU_RS05800
uniprot id: E8RAK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

765177:DESMU RS02810
gene id: 765177:DESMU_RS02810
uniprot id: E8R8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS04145
gene id: 765177:DESMU_RS04145
uniprot id: E8R9E7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

765177:DESMU RS03460
gene id: 765177:DESMU_RS03460
uniprot id: E8R912
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS03745
gene id: 765177:DESMU_RS03745
uniprot id: E8R970
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS00170
gene id: 765177:DESMU_RS00170
uniprot id: E8RAE2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

765177:DESMU RS05245
gene id: 765177:DESMU_RS05245
uniprot id: E8RA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS00975
gene id: 765177:DESMU_RS00975
uniprot id: E8R7L0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

765177:DESMU RS04805
gene id: 765177:DESMU_RS04805
uniprot id: E8R9S7
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

765177:DESMU RS06875
gene id: 765177:DESMU_RS06875
uniprot id: E8R7H7
names: Similarity
messages: Belongs to the MEMO1 family.

765177:DESMU RS04175
gene id: 765177:DESMU_RS04175
uniprot id: E8R9F3
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

765177:DESMU RS05980
gene id: 765177:DESMU_RS05980
uniprot id: E8RAN6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

765177:DESMU RS05475
gene id: 765177:DESMU_RS05475
uniprot id: E8RA73
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

765177:DESMU RS04740
gene id: 765177:DESMU_RS04740
uniprot id: E8R9R4
names: Similarity
messages: Belongs to the UPF0045 family.

765177:DESMU RS06885
gene id: 765177:DESMU_RS06885
uniprot id: E8R7H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS04220
gene id: 765177:DESMU_RS04220
uniprot id: E8R9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS03475
gene id: 765177:DESMU_RS03475
uniprot id: E8R915
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS01005
gene id: 765177:DESMU_RS01005
uniprot id: E8R7L6
names: Similarity
messages: Belongs to the group II decarboxylase family.

765177:DESMU RS00345
gene id: 765177:DESMU_RS00345
uniprot id: E8RAH3
names: Subcellular Location Annotation
messages: Cell membrane

765177:DESMU RS03520
gene id: 765177:DESMU_RS03520
uniprot id: E8R923
names: Similarity
messages: Belongs to the thymidylate kinase family.

765177:DESMU RS06225
gene id: 765177:DESMU_RS06225
uniprot id: E8R757
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

765177:DESMU RS05910
gene id: 765177:DESMU_RS05910
uniprot id: E8RAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS05140
gene id: 765177:DESMU_RS05140
uniprot id: E8R9Z1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS03345
gene id: 765177:DESMU_RS03345
uniprot id: E8R8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

765177:DESMU RS06105
gene id: 765177:DESMU_RS06105
uniprot id: E8RAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

765177:DESMU RS04275
gene id: 765177:DESMU_RS04275
uniprot id: E8R9H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

765177:DESMU RS02980
gene id: 765177:DESMU_RS02980
uniprot id: E8R8R8
names: Similarity
messages: Belongs to the UPF0200 family.

765177:DESMU RS06975
gene id: 765177:DESMU_RS06975
uniprot id: E8R7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS03505
gene id: 765177:DESMU_RS03505
uniprot id: E8R920
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

765177:DESMU RS04400
gene id: 765177:DESMU_RS04400
uniprot id: E8R9J7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

765177:DESMU RS06910
gene id: 765177:DESMU_RS06910
uniprot id: E8R7Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS04150
gene id: 765177:DESMU_RS04150
uniprot id: E8R9E8
names: Similarity
messages: Belongs to the HupF/HypC family.

765177:DESMU RS06915
gene id: 765177:DESMU_RS06915
uniprot id: E8R7Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

765177:DESMU RS05370
gene id: 765177:DESMU_RS05370
uniprot id: E8RA33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

765177:DESMU RS03470
gene id: 765177:DESMU_RS03470
uniprot id: E8R914
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

765177:DESMU RS03455
gene id: 765177:DESMU_RS03455
uniprot id: E8R911
names: Similarity
messages: Belongs to the GcvT family.

765177:DESMU RS00660
gene id: 765177:DESMU_RS00660
uniprot id: E8R710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS02865
gene id: 765177:DESMU_RS02865
uniprot id: E8R8P6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

765177:DESMU RS05095
gene id: 765177:DESMU_RS05095
uniprot id: E8R9Y5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS03485
gene id: 765177:DESMU_RS03485
uniprot id: E8R917
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05700
gene id: 765177:DESMU_RS05700
uniprot id: E8RAB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS06670
gene id: 765177:DESMU_RS06670
uniprot id: E8R7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

765177:DESMU RS03730
gene id: 765177:DESMU_RS03730
uniprot id: E8R967
names: Similarity
messages: Belongs to the Nth/MutY family.

765177:DESMU RS06970
gene id: 765177:DESMU_RS06970
uniprot id: E8R7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

765177:DESMU RS04715
gene id: 765177:DESMU_RS04715
uniprot id: E8R9Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS00370
gene id: 765177:DESMU_RS00370
uniprot id: E8RAH7
names: Similarity
messages: Belongs to the PGI/PMI family.

765177:DESMU RS04445
gene id: 765177:DESMU_RS04445
uniprot id: E8R9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

765177:DESMU RS05580
gene id: 765177:DESMU_RS05580
uniprot id: E8RA93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

765177:DESMU RS00680
gene id: 765177:DESMU_RS00680
uniprot id: E8R714
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

765177:DESMU RS06835
gene id: 765177:DESMU_RS06835
uniprot id: E8R7G9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

765177:DESMU RS06820
gene id: 765177:DESMU_RS06820
uniprot id: E8R7G6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

765177:DESMU RS00260
gene id: 765177:DESMU_RS00260
uniprot id: E8RAF8
names: Similarity
messages: Belongs to the eIF-2-alpha family.

765177:DESMU RS05555
gene id: 765177:DESMU_RS05555
uniprot id: E8RA88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

765177:DESMU RS04190
gene id: 765177:DESMU_RS04190
uniprot id: E8R9F6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

765177:DESMU RS00120
gene id: 765177:DESMU_RS00120
uniprot id: E8RAD2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

765177:DESMU RS02665
gene id: 765177:DESMU_RS02665
uniprot id: E8R8K7
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05070
gene id: 765177:DESMU_RS05070
uniprot id: E8R9Y0
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

765177:DESMU RS02920
gene id: 765177:DESMU_RS02920
uniprot id: E8R8Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS04850
gene id: 765177:DESMU_RS04850
uniprot id: E8R9T6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

765177:DESMU RS02015
gene id: 765177:DESMU_RS02015
uniprot id: E8R884
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

765177:DESMU RS00400
gene id: 765177:DESMU_RS00400
uniprot id: E8RAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

765177:DESMU RS06905
gene id: 765177:DESMU_RS06905
uniprot id: E8R7Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

765177:DESMU RS04300
gene id: 765177:DESMU_RS04300
uniprot id: E8R9H7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

765177:DESMU RS03610
gene id: 765177:DESMU_RS03610
uniprot id: E8R942
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

765177:DESMU RS01830
gene id: 765177:DESMU_RS01830
uniprot id: E8R846
names: Similarity
messages: Belongs to the HerA family.

765177:DESMU RS00430
gene id: 765177:DESMU_RS00430
uniprot id: E8RAI9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

765177:DESMU RS06855
gene id: 765177:DESMU_RS06855
uniprot id: E8R7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

765177:DESMU RS01720
gene id: 765177:DESMU_RS01720
uniprot id: E8R824
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

765177:DESMU RS05565
gene id: 765177:DESMU_RS05565
uniprot id: E8RA90
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

765177:DESMU RS00055
gene id: 765177:DESMU_RS00055
uniprot id: E8RA51
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

765177:DESMU RS01680
gene id: 765177:DESMU_RS01680
uniprot id: E8R816
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS05170
gene id: 765177:DESMU_RS05170
uniprot id: E8R9Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

765177:DESMU RS06880
gene id: 765177:DESMU_RS06880
uniprot id: E8R7H8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

765177:DESMU RS05695
gene id: 765177:DESMU_RS05695
uniprot id: E8RAB5
names: Similarity
messages: Belongs to the PDCD5 family.

765177:DESMU RS03570
gene id: 765177:DESMU_RS03570
uniprot id: E8R934
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

765177:DESMU RS06365
gene id: 765177:DESMU_RS06365
uniprot id: E8R782
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

765177:DESMU RS03835
gene id: 765177:DESMU_RS03835
uniprot id: E8R988
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

765177:DESMU RS02910
gene id: 765177:DESMU_RS02910
uniprot id: E8R8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

765177:DESMU RS05630
gene id: 765177:DESMU_RS05630
uniprot id: E8RAA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

765177:DESMU RS01845
gene id: 765177:DESMU_RS01845
uniprot id: E8R849
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

765177:DESMU RS05685
gene id: 765177:DESMU_RS05685
uniprot id: E8RAB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

765177:DESMU RS06115
gene id: 765177:DESMU_RS06115
uniprot id: E8RAR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

765177:DESMU RS05945
gene id: 765177:DESMU_RS05945
uniprot id: E8RAM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS00495
gene id: 765177:DESMU_RS00495
uniprot id: E8R6X9
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS01235
gene id: 765177:DESMU_RS01235
uniprot id: E8R7S8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS02000
gene id: 765177:DESMU_RS02000
uniprot id: E8R881
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

765177:DESMU RS00295
gene id: 765177:DESMU_RS00295
uniprot id: E8RAG5
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS02620
gene id: 765177:DESMU_RS02620
uniprot id: E8R8J8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

765177:DESMU RS00230
gene id: 765177:DESMU_RS00230
uniprot id: E8RAF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

765177:DESMU RS05240
gene id: 765177:DESMU_RS05240
uniprot id: E8RA09
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

765177:DESMU RS06395
gene id: 765177:DESMU_RS06395
uniprot id: E8R788
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

765177:DESMU RS00555
gene id: 765177:DESMU_RS00555
uniprot id: E8R6Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

765177:DESMU RS01125
gene id: 765177:DESMU_RS01125
uniprot id: E8R7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS04900
gene id: 765177:DESMU_RS04900
uniprot id: E8R9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

765177:DESMU RS00835
gene id: 765177:DESMU_RS00835
uniprot id: E8R7I3
names: Similarity
messages: Belongs to the carbamate kinase family.

765177:DESMU RS02510
gene id: 765177:DESMU_RS02510
uniprot id: E8R8H6
names: Similarity
messages: Belongs to the UPF0111 family.

765177:DESMU RS04215
gene id: 765177:DESMU_RS04215
uniprot id: E8R9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

765177:DESMU RS06850
gene id: 765177:DESMU_RS06850
uniprot id: E8R7H2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

765177:DESMU RS00500
gene id: 765177:DESMU_RS00500
uniprot id: E8R6Y0
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06780
gene id: 765177:DESMU_RS06780
uniprot id: E8R7F8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

765177:DESMU RS05785
gene id: 765177:DESMU_RS05785
uniprot id: E8RAK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

765177:DESMU RS03385
gene id: 765177:DESMU_RS03385
uniprot id: E8R8Z7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

765177:DESMU RS04325
gene id: 765177:DESMU_RS04325
uniprot id: E8R9I2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

765177:DESMU RS00515
gene id: 765177:DESMU_RS00515
uniprot id: E8R6Y4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

765177:DESMU RS03760
gene id: 765177:DESMU_RS03760
uniprot id: E8R973
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

765177:DESMU RS06000
gene id: 765177:DESMU_RS06000
uniprot id: E8RAP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

765177:DESMU RS02535
gene id: 765177:DESMU_RS02535
uniprot id: E8R8I1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06690
gene id: 765177:DESMU_RS06690
uniprot id: E8R7E1
names: Function
messages: Probably involved in the biogenesis of the ribosome.

765177:DESMU RS06695
gene id: 765177:DESMU_RS06695
uniprot id: E8R7E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

765177:DESMU RS02655
gene id: 765177:DESMU_RS02655
uniprot id: E8R8K5
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS00550
gene id: 765177:DESMU_RS00550
uniprot id: E8R6Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS01610
gene id: 765177:DESMU_RS01610
uniprot id: E8R802
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

765177:DESMU RS05325
gene id: 765177:DESMU_RS05325
uniprot id: E8RA26
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

765177:DESMU RS05090
gene id: 765177:DESMU_RS05090
uniprot id: E8R9Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

765177:DESMU RS00195
gene id: 765177:DESMU_RS00195
uniprot id: E8RAE6
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

765177:DESMU RS04405
gene id: 765177:DESMU_RS04405
uniprot id: E8R9J8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

765177:DESMU RS00845
gene id: 765177:DESMU_RS00845
uniprot id: E8R7I5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

765177:DESMU RS06300
gene id: 765177:DESMU_RS06300
uniprot id: E8R769
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

765177:DESMU RS02790
gene id: 765177:DESMU_RS02790
uniprot id: E8R8N1
names: Subcellular Location Annotation
messages: Membrane

765177:DESMU RS06680
gene id: 765177:DESMU_RS06680
uniprot id: E8R7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

765177:DESMU RS05960
gene id: 765177:DESMU_RS05960
uniprot id: E8RAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

765177:DESMU RS06440
gene id: 765177:DESMU_RS06440
uniprot id: E8R796
names: Similarity
messages: Belongs to the peptidase S8 family.

765177:DESMU RS00190
gene id: 765177:DESMU_RS00190
uniprot id: E8RAE5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

765177:DESMU RS03895
gene id: 765177:DESMU_RS03895
uniprot id: E8R997
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer composed of an alpha and a beta subunit.
messages: Heterodimer of the IorA and IorB subunits.

765177:DESMU RS04380
gene id: 765177:DESMU_RS04380
uniprot id: E8R9J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

765177:DESMU RS01855
gene id: 765177:DESMU_RS01855
uniprot id: E8R851
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

765177:DESMU RS06895
gene id: 765177:DESMU_RS06895
uniprot id: E8R7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

765177:DESMU RS03105
gene id: 765177:DESMU_RS03105
uniprot id: E8R8U2
names: Subcellular Location Annotation
messages: Membrane