76114:EB RS01455
gene id: 76114:EB_RS01455
uniprot id: Q5P8E7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

76114:EB RS13485
gene id: 76114:EB_RS13485
uniprot id: Q5P1E5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

76114:EB RS12125
gene id: 76114:EB_RS12125
uniprot id: Q5P266
names: Similarity
messages: Belongs to the CFA/CMAS family.

76114:EB RS03295
gene id: 76114:EB_RS03295
uniprot id: Q5P7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

76114:EB RS04495
gene id: 76114:EB_RS04495
uniprot id: Q5P6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

76114:EB RS07730
gene id: 76114:EB_RS07730
uniprot id: Q5P4T2
names: Subunit
messages: Homodimer.

76114:EB RS06185
gene id: 76114:EB_RS06185
uniprot id: Q5P5Q1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS00450
gene id: 76114:EB_RS00450
uniprot id: Q5P901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

76114:EB RS07870
gene id: 76114:EB_RS07870
uniprot id: Q5P4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

76114:EB RS13520
gene id: 76114:EB_RS13520
uniprot id: Q5P1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

76114:EB RS11525
gene id: 76114:EB_RS11525
uniprot id: Q5P2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

76114:EB RS00335
gene id: 76114:EB_RS00335
uniprot id: Q5P925
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

76114:EB RS02910
gene id: 76114:EB_RS02910
uniprot id: Q5P7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

76114:EB RS17335
gene id: 76114:EB_RS17335
uniprot id: Q5P8B0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS18680
gene id: 76114:EB_RS18680
uniprot id: Q5NYB7
names: Similarity
messages: Belongs to the citrate synthase family.

76114:EB RS07550
gene id: 76114:EB_RS07550
uniprot id: Q5P4X0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

76114:EB RS15505
gene id: 76114:EB_RS15505
uniprot id: Q5P081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

76114:EB RS02330
gene id: 76114:EB_RS02330
uniprot id: Q5P7X8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

76114:EB RS17270
gene id: 76114:EB_RS17270
uniprot id: Q5NZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

76114:EB RS16515
gene id: 76114:EB_RS16515
uniprot id: Q5NZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS06290
gene id: 76114:EB_RS06290
uniprot id: Q5P5N0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

76114:EB RS06475
gene id: 76114:EB_RS06475
uniprot id: Q5P5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

76114:EB RS06215
gene id: 76114:EB_RS06215
uniprot id: Q5P5P5
names: Similarity
messages: Belongs to the glutamate synthase family.

76114:EB RS15705
gene id: 76114:EB_RS15705
uniprot id: Q5P035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

76114:EB RS21050
gene id: 76114:EB_RS21050
uniprot id: Q5NWX1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

76114:EB RS05730
gene id: 76114:EB_RS05730
uniprot id: Q5P5Z9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS12715
gene id: 76114:EB_RS12715
uniprot id: Q5P1V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

76114:EB RS12020
gene id: 76114:EB_RS12020
uniprot id: Q5P288
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS12095
gene id: 76114:EB_RS12095
uniprot id: Q5P273
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

76114:EB RS08860
gene id: 76114:EB_RS08860
uniprot id: Q5P448
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

76114:EB RS09750
gene id: 76114:EB_RS09750
uniprot id: Q5P3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

76114:EB RS08975
gene id: 76114:EB_RS08975
uniprot id: Q5P413
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS10690
gene id: 76114:EB_RS10690
uniprot id: Q5P308
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

76114:EB RS10655
gene id: 76114:EB_RS10655
uniprot id: Q5P315
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

76114:EB RS13895
gene id: 76114:EB_RS13895
uniprot id: Q5P160
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

76114:EB RS10995
gene id: 76114:EB_RS10995
uniprot id: Q5P2U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

76114:EB RS04450
gene id: 76114:EB_RS04450
uniprot id: Q5P6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

76114:EB RS11155
gene id: 76114:EB_RS11155
uniprot id: Q5P2R3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

76114:EB RS19450
gene id: 76114:EB_RS19450
uniprot id: Q5NXV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

76114:EB RS11825
gene id: 76114:EB_RS11825
uniprot id: Q5P2D0
names: Similarity
messages: Belongs to the FemABX family.

76114:EB RS13200
gene id: 76114:EB_RS13200
uniprot id: Q5P1K2
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

76114:EB RS16960
gene id: 76114:EB_RS16960
uniprot id: Q5NZC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

76114:EB RS09030
gene id: 76114:EB_RS09030
uniprot id: Q5P409
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

76114:EB RS11815
gene id: 76114:EB_RS11815
uniprot id: Q5P2D2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

76114:EB RS06410
gene id: 76114:EB_RS06410
uniprot id: Q5P5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

76114:EB RS07420
gene id: 76114:EB_RS07420
uniprot id: Q5P4Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS02410
gene id: 76114:EB_RS02410
uniprot id: Q5P7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

76114:EB RS10505
gene id: 76114:EB_RS10505
uniprot id: Q5P345
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS08325
gene id: 76114:EB_RS08325
uniprot id: Q5P4F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS16690
gene id: 76114:EB_RS16690
uniprot id: Q5NZI4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS08790
gene id: 76114:EB_RS08790
uniprot id: Q5P463
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS10705
gene id: 76114:EB_RS10705
uniprot id: Q5P305
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

76114:EB RS04150
gene id: 76114:EB_RS04150
uniprot id: Q5P6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

76114:EB RS18465
gene id: 76114:EB_RS18465
uniprot id: Q5NYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

76114:EB RS03550
gene id: 76114:EB_RS03550
uniprot id: Q5P794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

76114:EB RS08445
gene id: 76114:EB_RS08445
uniprot id: Q5P4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

76114:EB RS14840
gene id: 76114:EB_RS14840
uniprot id: Q5P0L6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS03110
gene id: 76114:EB_RS03110
uniprot id: Q5P7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

76114:EB RS00435
gene id: 76114:EB_RS00435
uniprot id: Q5P903
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

76114:EB RS11730
gene id: 76114:EB_RS11730
uniprot id: Q5P2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

76114:EB RS19795
gene id: 76114:EB_RS19795
uniprot id: Q5NXP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

76114:EB RS12295
gene id: 76114:EB_RS12295
uniprot id: Q5P233
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS13665
gene id: 76114:EB_RS13665
uniprot id: Q5P1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

76114:EB RS07150
gene id: 76114:EB_RS07150
uniprot id: Q5P554
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

76114:EB RS07985
gene id: 76114:EB_RS07985
uniprot id: Q5P4M1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

76114:EB RS02830
gene id: 76114:EB_RS02830
uniprot id: Q5P7N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

76114:EB RS04690
gene id: 76114:EB_RS04690
uniprot id: Q5P6L8
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS00865
gene id: 76114:EB_RS00865
uniprot id: Q5P8S1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

76114:EB RS10535
gene id: 76114:EB_RS10535
uniprot id: Q5P339
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

76114:EB RS06430
gene id: 76114:EB_RS06430
uniprot id: Q5P5K1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS15490
gene id: 76114:EB_RS15490
uniprot id: Q5P084
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

76114:EB RS02915
gene id: 76114:EB_RS02915
uniprot id: Q5P7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

76114:EB RS09380
gene id: 76114:EB_RS09380
uniprot id: Q5P3S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

76114:EB RS02155
gene id: 76114:EB_RS02155
uniprot id: Q5P811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Monomer.

76114:EB RS13215
gene id: 76114:EB_RS13215
uniprot id: Q5P1J9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

76114:EB RS21280
gene id: 76114:EB_RS21280
uniprot id: Q5NWR4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

76114:EB RS07395
gene id: 76114:EB_RS07395
uniprot id: Q5P4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

76114:EB RS04425
gene id: 76114:EB_RS04425
uniprot id: Q5P6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS15240
gene id: 76114:EB_RS15240
uniprot id: Q5P0D3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

76114:EB RS05550
gene id: 76114:EB_RS05550
uniprot id: Q5P637
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS12930
gene id: 76114:EB_RS12930
uniprot id: Q5P1Q4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS10540
gene id: 76114:EB_RS10540
uniprot id: Q5P338
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

76114:EB RS05455
gene id: 76114:EB_RS05455
uniprot id: Q5P656
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS12345
gene id: 76114:EB_RS12345
uniprot id: Q5P228
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

76114:EB RS19120
gene id: 76114:EB_RS19120
uniprot id: Q5NY19
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

76114:EB RS05365
gene id: 76114:EB_RS05365
uniprot id: Q5P677
names: Similarity
messages: Belongs to the universal stress protein A family.

76114:EB RS07310
gene id: 76114:EB_RS07310
uniprot id: Q5P517
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS14795
gene id: 76114:EB_RS14795
uniprot id: Q5P0M5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS19050
gene id: 76114:EB_RS19050
uniprot id: Q5NY33
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

76114:EB RS02180
gene id: 76114:EB_RS02180
uniprot id: Q5P806
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

76114:EB RS04710
gene id: 76114:EB_RS04710
uniprot id: Q5P6L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

76114:EB RS17875
gene id: 76114:EB_RS17875
uniprot id: Q5NYT2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

76114:EB RS00350
gene id: 76114:EB_RS00350
uniprot id: Q5P922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

76114:EB RS18570
gene id: 76114:EB_RS18570
uniprot id: Q5NYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

76114:EB RS15720
gene id: 76114:EB_RS15720
uniprot id: Q5P031
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS08215
gene id: 76114:EB_RS08215
uniprot id: Q5P4H6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

76114:EB RS12380
gene id: 76114:EB_RS12380
uniprot id: Q5P221
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

76114:EB RS14520
gene id: 76114:EB_RS14520
uniprot id: Q5P0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

76114:EB RS16160
gene id: 76114:EB_RS16160
uniprot id: Q5NZT9
names: Similarity
messages: Belongs to the RecJ family.

76114:EB RS16780
gene id: 76114:EB_RS16780
uniprot id: Q5NZG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

76114:EB RS08120
gene id: 76114:EB_RS08120
uniprot id: Q5P4J5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS10555
gene id: 76114:EB_RS10555
uniprot id: Q5P335
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

76114:EB RS12220
gene id: 76114:EB_RS12220
uniprot id: Q5P248
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

76114:EB RS04090
gene id: 76114:EB_RS04090
uniprot id: Q5P6Y8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

76114:EB RS10990
gene id: 76114:EB_RS10990
uniprot id: Q5P2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

76114:EB RS10320
gene id: 76114:EB_RS10320
uniprot id: Q5P381
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

76114:EB RS16270
gene id: 76114:EB_RS16270
uniprot id: Q5NZR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

76114:EB RS09385
gene id: 76114:EB_RS09385
uniprot id: Q5P3S4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

76114:EB RS06635
gene id: 76114:EB_RS06635
uniprot id: Q5P5G4
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.
messages: Belongs to the HyuA family.
messages: By ethylbenzene, toluene and acetophenone.
messages: Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
messages: Cytoplasm
messages: Divalent metal cations. Magnesium or manganese are required for activity.
messages: Inhibited by zinc ions, carbamoylphosphate and beta,gamma-imido-ATP.

76114:EB RS13820
gene id: 76114:EB_RS13820
uniprot id: Q5P176
names: Similarity
messages: Belongs to the PhoH family.

76114:EB RS13175
gene id: 76114:EB_RS13175
uniprot id: Q5P1K8
names: Similarity
messages: Belongs to the thioredoxin family.

76114:EB RS13125
gene id: 76114:EB_RS13125
uniprot id: Q5P1L2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS12140
gene id: 76114:EB_RS12140
uniprot id: Q5P264
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

76114:EB RS14315
gene id: 76114:EB_RS14315
uniprot id: Q5P0X6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

76114:EB RS04535
gene id: 76114:EB_RS04535
uniprot id: Q5P6P6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS11650
gene id: 76114:EB_RS11650
uniprot id: Q5P2G6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS18030
gene id: 76114:EB_RS18030
uniprot id: Q5NYP8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

76114:EB RS08155
gene id: 76114:EB_RS08155
uniprot id: Q5P4I8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS09095
gene id: 76114:EB_RS09095
uniprot id: Q5P3Y6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

76114:EB RS09125
gene id: 76114:EB_RS09125
uniprot id: Q5P3X9
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

76114:EB RS16760
gene id: 76114:EB_RS16760
uniprot id: Q5NZG9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

76114:EB RS16090
gene id: 76114:EB_RS16090
uniprot id: Q5NZV6
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

76114:EB RS13090
gene id: 76114:EB_RS13090
uniprot id: Q5P1M0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

76114:EB RS12895
gene id: 76114:EB_RS12895
uniprot id: Q5P1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

76114:EB RS17790
gene id: 76114:EB_RS17790
uniprot id: Q5NYV0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

76114:EB RS11385
gene id: 76114:EB_RS11385
uniprot id: Q5P2L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

76114:EB RS13620
gene id: 76114:EB_RS13620
uniprot id: Q5P1B6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

76114:EB RS07425
gene id: 76114:EB_RS07425
uniprot id: Q5P4Z2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

76114:EB RS10710
gene id: 76114:EB_RS10710
uniprot id: Q5P304
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

76114:EB RS13425
gene id: 76114:EB_RS13425
uniprot id: Q5P1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

76114:EB RS02630
gene id: 76114:EB_RS02630
uniprot id: Q5P7S4
names: Similarity
messages: Belongs to the peptidase U62 family.

76114:EB RS16250
gene id: 76114:EB_RS16250
uniprot id: Q5NZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

76114:EB RS15130
gene id: 76114:EB_RS15130
uniprot id: Q5P0F5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

76114:EB RS13580
gene id: 76114:EB_RS13580
uniprot id: Q5P1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

76114:EB RS07375
gene id: 76114:EB_RS07375
uniprot id: Q5P502
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

76114:EB RS04880
gene id: 76114:EB_RS04880
uniprot id: Q5P6H9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

76114:EB RS21655
gene id: 76114:EB_RS21655
uniprot id: Q5NWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

76114:EB RS00155
gene id: 76114:EB_RS00155
uniprot id: Q5P968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

76114:EB RS21415
gene id: 76114:EB_RS21415
uniprot id: Q5NWN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS11220
gene id: 76114:EB_RS11220
uniprot id: Q5P2P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

76114:EB RS09045
gene id: 76114:EB_RS09045
uniprot id: Q5P8B0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS12560
gene id: 76114:EB_RS12560
uniprot id: Q5P1Y1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

76114:EB RS10670
gene id: 76114:EB_RS10670
uniprot id: Q5P312
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

76114:EB RS10600
gene id: 76114:EB_RS10600
uniprot id: Q5P326
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

76114:EB RS17730
gene id: 76114:EB_RS17730
uniprot id: Q5P070
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS01730
gene id: 76114:EB_RS01730
uniprot id: Q5P897
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS07580
gene id: 76114:EB_RS07580
uniprot id: Q5P4W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

76114:EB RS16260
gene id: 76114:EB_RS16260
uniprot id: Q5NZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

76114:EB RS09200
gene id: 76114:EB_RS09200
uniprot id: Q5P3W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

76114:EB RS04800
gene id: 76114:EB_RS04800
uniprot id: Q5P6J5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

76114:EB RS06055
gene id: 76114:EB_RS06055
uniprot id: Q5P5S9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

76114:EB RS08185
gene id: 76114:EB_RS08185
uniprot id: Q5P4I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

76114:EB RS14935
gene id: 76114:EB_RS14935
uniprot id: Q5P0J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS18035
gene id: 76114:EB_RS18035
uniprot id: Q5NYP7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

76114:EB RS18915
gene id: 76114:EB_RS18915
uniprot id: Q5NY59
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS13515
gene id: 76114:EB_RS13515
uniprot id: Q5P1D9
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS14105
gene id: 76114:EB_RS14105
uniprot id: Q5P119
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

76114:EB RS08140
gene id: 76114:EB_RS08140
uniprot id: Q5P4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

76114:EB RS17385
gene id: 76114:EB_RS17385
uniprot id: Q5NZ36
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

76114:EB RS13385
gene id: 76114:EB_RS13385
uniprot id: Q5P1G4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS14150
gene id: 76114:EB_RS14150
uniprot id: Q5P109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

76114:EB RS08330
gene id: 76114:EB_RS08330
uniprot id: Q5P4F1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS06670
gene id: 76114:EB_RS06670
uniprot id: Q5P5F4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

76114:EB RS15990
gene id: 76114:EB_RS15990
uniprot id: Q5NZX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

76114:EB RS10330
gene id: 76114:EB_RS10330
uniprot id: Q5P378
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS14155
gene id: 76114:EB_RS14155
uniprot id: Q5P108
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

76114:EB RS11860
gene id: 76114:EB_RS11860
uniprot id: Q5P2C3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

76114:EB RS04930
gene id: 76114:EB_RS04930
uniprot id: Q5P6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

76114:EB RS15135
gene id: 76114:EB_RS15135
uniprot id: Q5P0F4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

76114:EB RS05535
gene id: 76114:EB_RS05535
uniprot id: Q5P640
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS07595
gene id: 76114:EB_RS07595
uniprot id: Q5P4W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

76114:EB RS11710
gene id: 76114:EB_RS11710
uniprot id: Q5P2F4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

76114:EB RS04555
gene id: 76114:EB_RS04555
uniprot id: Q5P6P2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

76114:EB RS12050
gene id: 76114:EB_RS12050
uniprot id: Q5P282
names: Similarity
messages: Belongs to the barstar family.

76114:EB RS00640
gene id: 76114:EB_RS00640
uniprot id: Q5P8W5
names: Similarity
messages: Belongs to the universal stress protein A family.

76114:EB RS02315
gene id: 76114:EB_RS02315
uniprot id: Q5P7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

76114:EB RS17895
gene id: 76114:EB_RS17895
uniprot id: Q5NYS8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

76114:EB RS21260
gene id: 76114:EB_RS21260
uniprot id: Q5NWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

76114:EB RS16240
gene id: 76114:EB_RS16240
uniprot id: Q5NZS4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

76114:EB RS14850
gene id: 76114:EB_RS14850
uniprot id: Q5P0L4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS17355
gene id: 76114:EB_RS17355
uniprot id: Q5NZ43
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

76114:EB RS22035
gene id: 76114:EB_RS22035
uniprot id: Q5NWB7
names: Similarity
messages: Belongs to the ParB family.

76114:EB RS04020
gene id: 76114:EB_RS04020
uniprot id: Q5P701
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

76114:EB RS14280
gene id: 76114:EB_RS14280
uniprot id: Q5P0Y3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

76114:EB RS18950
gene id: 76114:EB_RS18950
uniprot id: Q5NY52
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

76114:EB RS15590
gene id: 76114:EB_RS15590
uniprot id: Q5P062
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

76114:EB RS04830
gene id: 76114:EB_RS04830
uniprot id: Q5P6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

76114:EB RS00385
gene id: 76114:EB_RS00385
uniprot id: Q5P915
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

76114:EB RS11020
gene id: 76114:EB_RS11020
uniprot id: Q5P2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

76114:EB RS11615
gene id: 76114:EB_RS11615
uniprot id: Q5P2H4
names: Similarity
messages: Belongs to the YjdM family.

76114:EB RS17890
gene id: 76114:EB_RS17890
uniprot id: Q5NYS9
names: Similarity
messages: Belongs to the HesB/IscA family.

76114:EB RS01735
gene id: 76114:EB_RS01735
uniprot id: Q5P896
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

76114:EB RS04520
gene id: 76114:EB_RS04520
uniprot id: Q5P6P9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

76114:EB RS10580
gene id: 76114:EB_RS10580
uniprot id: Q5P330
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

76114:EB RS16685
gene id: 76114:EB_RS16685
uniprot id: Q5NZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS10140
gene id: 76114:EB_RS10140
uniprot id: Q5P3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

76114:EB RS02960
gene id: 76114:EB_RS02960
uniprot id: Q5P7K9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

76114:EB RS14815
gene id: 76114:EB_RS14815
uniprot id: Q5P0M1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS19080
gene id: 76114:EB_RS19080
uniprot id: Q5NY25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

76114:EB RS03130
gene id: 76114:EB_RS03130
uniprot id: Q5P7H6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

76114:EB RS17260
gene id: 76114:EB_RS17260
uniprot id: Q5NZ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

76114:EB RS10605
gene id: 76114:EB_RS10605
uniprot id: Q5P325
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

76114:EB RS07285
gene id: 76114:EB_RS07285
uniprot id: Q5P524
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

76114:EB RS11100
gene id: 76114:EB_RS11100
uniprot id: Q5P2S5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

76114:EB RS03310
gene id: 76114:EB_RS03310
uniprot id: Q5P7D9
names: Similarity
messages: Belongs to the peptidase S8 family.

76114:EB RS13510
gene id: 76114:EB_RS13510
uniprot id: Q5P1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS13675
gene id: 76114:EB_RS13675
uniprot id: Q5P1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

76114:EB RS13725
gene id: 76114:EB_RS13725
uniprot id: Q5P196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS11340
gene id: 76114:EB_RS11340
uniprot id: Q5P2M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

76114:EB RS11610
gene id: 76114:EB_RS11610
uniprot id: Q5P2H5
names: Similarity
messages: Belongs to the thioredoxin family.

76114:EB RS02535
gene id: 76114:EB_RS02535
uniprot id: Q5P7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

76114:EB RS03865
gene id: 76114:EB_RS03865
uniprot id: Q5P730
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

76114:EB RS11675
gene id: 76114:EB_RS11675
uniprot id: Q5P2G1
names: Similarity
messages: Belongs to the TrpC family.

76114:EB RS17905
gene id: 76114:EB_RS17905
uniprot id: Q5NYS6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

76114:EB RS10570
gene id: 76114:EB_RS10570
uniprot id: Q5P332
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

76114:EB RS15820
gene id: 76114:EB_RS15820
uniprot id: Q5P011
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

76114:EB RS07670
gene id: 76114:EB_RS07670
uniprot id: Q5P4U4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS19750
gene id: 76114:EB_RS19750
uniprot id: Q5NXQ0
names: Similarity
messages: Belongs to the peptidase M1 family.

76114:EB RS14920
gene id: 76114:EB_RS14920
uniprot id: Q5P0J8
names: Similarity
messages: Belongs to the AOR/FOR family.

76114:EB RS13410
gene id: 76114:EB_RS13410
uniprot id: Q5P1F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

76114:EB RS15215
gene id: 76114:EB_RS15215
uniprot id: Q5P0D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

76114:EB RS12525
gene id: 76114:EB_RS12525
uniprot id: Q5P1Y8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

76114:EB RS01890
gene id: 76114:EB_RS01890
uniprot id: Q5P867
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS22370
gene id: 76114:EB_RS22370
uniprot id: Q5NW55
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS13230
gene id: 76114:EB_RS13230
uniprot id: Q5P1J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS08275
gene id: 76114:EB_RS08275
uniprot id: Q5P4G3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

76114:EB RS15260
gene id: 76114:EB_RS15260
uniprot id: Q5P0C9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

76114:EB RS17235
gene id: 76114:EB_RS17235
uniprot id: Q5NZ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

76114:EB RS18590
gene id: 76114:EB_RS18590
uniprot id: Q5NYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

76114:EB RS03415
gene id: 76114:EB_RS03415
uniprot id: Q5P7C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

76114:EB RS13360
gene id: 76114:EB_RS13360
uniprot id: Q5P1G8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

76114:EB RS02195
gene id: 76114:EB_RS02195
uniprot id: Q5P803
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

76114:EB RS01655
gene id: 76114:EB_RS01655
uniprot id: Q5P8B0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS03250
gene id: 76114:EB_RS03250
uniprot id: Q5P7F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

76114:EB RS06020
gene id: 76114:EB_RS06020
uniprot id: Q5P5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

76114:EB RS03470
gene id: 76114:EB_RS03470
uniprot id: Q5P7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

76114:EB RS03435
gene id: 76114:EB_RS03435
uniprot id: Q5P7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

76114:EB RS16425
gene id: 76114:EB_RS16425
uniprot id: Q5NZN7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

76114:EB RS10205
gene id: 76114:EB_RS10205
uniprot id: Q5P3A4
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS07250
gene id: 76114:EB_RS07250
uniprot id: Q5P532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

76114:EB RS15510
gene id: 76114:EB_RS15510
uniprot id: Q5P080
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

76114:EB RS08080
gene id: 76114:EB_RS08080
uniprot id: Q5P4K2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

76114:EB RS05030
gene id: 76114:EB_RS05030
uniprot id: Q5P6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

76114:EB RS00750
gene id: 76114:EB_RS00750
uniprot id: Q5P413
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS15995
gene id: 76114:EB_RS15995
uniprot id: Q5NZX8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

76114:EB RS18725
gene id: 76114:EB_RS18725
uniprot id: Q5NYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

76114:EB RS16830
gene id: 76114:EB_RS16830
uniprot id: Q5NZF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

76114:EB RS14350
gene id: 76114:EB_RS14350
uniprot id: Q5P0W9
names: Similarity
messages: Belongs to the universal stress protein A family.

76114:EB RS02015
gene id: 76114:EB_RS02015
uniprot id: Q5P838
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

76114:EB RS00210
gene id: 76114:EB_RS00210
uniprot id: Q5P952
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

76114:EB RS17850
gene id: 76114:EB_RS17850
uniprot id: Q5NYT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

76114:EB RS02485
gene id: 76114:EB_RS02485
uniprot id: Q5P7U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS12965
gene id: 76114:EB_RS12965
uniprot id: Q5P1P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

76114:EB RS01875
gene id: 76114:EB_RS01875
uniprot id: Q5P870
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS21645
gene id: 76114:EB_RS21645
uniprot id: Q5NWJ2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

76114:EB RS16945
gene id: 76114:EB_RS16945
uniprot id: Q5NZD0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

76114:EB RS09640
gene id: 76114:EB_RS09640
uniprot id: Q5P3M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

76114:EB RS15115
gene id: 76114:EB_RS15115
uniprot id: Q5P0F8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

76114:EB RS11685
gene id: 76114:EB_RS11685
uniprot id: Q5P2F9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

76114:EB RS06645
gene id: 76114:EB_RS06645
uniprot id: Q5P5G2
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.
messages: Belongs to the oxoprolinase family.
messages: By ethylbenzene, toluene and acetophenone.
messages: Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
messages: Cytoplasm
messages: Divalent metal cations. Magnesium or manganese are required for activity.
messages: Inhibited by zinc ions, carbamoylphosphate and beta,gamma-imido-ATP.

76114:EB RS15270
gene id: 76114:EB_RS15270
uniprot id: Q5P0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

76114:EB RS00215
gene id: 76114:EB_RS00215
uniprot id: Q5P951
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS22400
gene id: 76114:EB_RS22400
uniprot id: Q5NW49
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS05170
gene id: 76114:EB_RS05170
uniprot id: Q5P6B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

76114:EB RS10950
gene id: 76114:EB_RS10950
uniprot id: Q5P2V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

76114:EB RS18545
gene id: 76114:EB_RS18545
uniprot id: Q5NYE5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

76114:EB RS18280
gene id: 76114:EB_RS18280
uniprot id: Q5NYJ8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

76114:EB RS01685
gene id: 76114:EB_RS01685
uniprot id: Q5P8A6
names: Similarity
messages: Belongs to the aspartokinase family.

76114:EB RS04190
gene id: 76114:EB_RS04190
uniprot id: Q5P6W7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

76114:EB RS03995
gene id: 76114:EB_RS03995
uniprot id: Q5P706
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

76114:EB RS04120
gene id: 76114:EB_RS04120
uniprot id: Q5P6Y1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

76114:EB RS10625
gene id: 76114:EB_RS10625
uniprot id: Q5P321
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

76114:EB RS06525
gene id: 76114:EB_RS06525
uniprot id: Q5P5I5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

76114:EB RS11750
gene id: 76114:EB_RS11750
uniprot id: Q5P2E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS22030
gene id: 76114:EB_RS22030
uniprot id: Q5NWB8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

76114:EB RS17140
gene id: 76114:EB_RS17140
uniprot id: Q5NZ87
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

76114:EB RS14845
gene id: 76114:EB_RS14845
uniprot id: Q5P0L5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS03660
gene id: 76114:EB_RS03660
uniprot id: Q5P772
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS01710
gene id: 76114:EB_RS01710
uniprot id: Q5P8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

76114:EB RS19555
gene id: 76114:EB_RS19555
uniprot id: Q5NXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

76114:EB RS18850
gene id: 76114:EB_RS18850
uniprot id: Q5NY73
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

76114:EB RS00195
gene id: 76114:EB_RS00195
uniprot id: Q5P955
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

76114:EB RS00530
gene id: 76114:EB_RS00530
uniprot id: Q5P8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

76114:EB RS10575
gene id: 76114:EB_RS10575
uniprot id: Q5P331
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

76114:EB RS11280
gene id: 76114:EB_RS11280
uniprot id: Q5P2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

76114:EB RS18040
gene id: 76114:EB_RS18040
uniprot id: Q5NYP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

76114:EB RS17845
gene id: 76114:EB_RS17845
uniprot id: Q5NYT8
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS00660
gene id: 76114:EB_RS00660
uniprot id: Q5P8W1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

76114:EB RS08590
gene id: 76114:EB_RS08590
uniprot id: Q5P4A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

76114:EB RS18880
gene id: 76114:EB_RS18880
uniprot id: Q5NY68
names: Similarity
messages: Belongs to the cytochrome P450 family.

76114:EB RS14050
gene id: 76114:EB_RS14050
uniprot id: Q5P131
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

76114:EB RS19055
gene id: 76114:EB_RS19055
uniprot id: Q5NY31
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS08775
gene id: 76114:EB_RS08775
uniprot id: Q5P467
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

76114:EB RS08220
gene id: 76114:EB_RS08220
uniprot id: Q5P4H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

76114:EB RS01925
gene id: 76114:EB_RS01925
uniprot id: Q5P859
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

76114:EB RS12810
gene id: 76114:EB_RS12810
uniprot id: Q5P1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

76114:EB RS18705
gene id: 76114:EB_RS18705
uniprot id: Q5NYB2
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

76114:EB RS02400
gene id: 76114:EB_RS02400
uniprot id: Q5P7W5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

76114:EB RS04795
gene id: 76114:EB_RS04795
uniprot id: Q5P6J6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS06625
gene id: 76114:EB_RS06625
uniprot id: Q5P5G6
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.
messages: By ethylbenzene, toluene and acetophenone.
messages: Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
messages: Cytoplasm
messages: Divalent metal cations. Magnesium or manganese are required for activity.
messages: Inhibited by zinc ions, carbamoylphosphate and beta,gamma-imido-ATP.
messages: The epsilon subunit dissociates during enzyme purification. However, Apc5 is required for acetophenone carboxylation and the enzyme complex is reconstituted using recombinant Apc5.

76114:EB RS06530
gene id: 76114:EB_RS06530
uniprot id: Q5P5I4
names: Biotechnology
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NAD-dependent stereospecific oxidation of (S)-1-phenylethanol to acetophenone in the degradation of ethylbenzene.
messages: Homotetramer.
messages: The reverse reaction is of biotechnological interest for the specific production of chiral alcohols from ketones.

76114:EB RS10100
gene id: 76114:EB_RS10100
uniprot id: Q5P3C5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

76114:EB RS12880
gene id: 76114:EB_RS12880
uniprot id: Q5P1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

76114:EB RS12385
gene id: 76114:EB_RS12385
uniprot id: Q5P220
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

76114:EB RS07605
gene id: 76114:EB_RS07605
uniprot id: Q5P4V9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

76114:EB RS10250
gene id: 76114:EB_RS10250
uniprot id: Q5P395
names: Similarity
messages: Belongs to the peptidase A24 family.

76114:EB RS18625
gene id: 76114:EB_RS18625
uniprot id: Q5NYC8
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

76114:EB RS03025
gene id: 76114:EB_RS03025
uniprot id: Q5P7J5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

76114:EB RS15945
gene id: 76114:EB_RS15945
uniprot id: Q5NZY5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS03185
gene id: 76114:EB_RS03185
uniprot id: Q5P7G6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

76114:EB RS08240
gene id: 76114:EB_RS08240
uniprot id: Q5P4H1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

76114:EB RS18195
gene id: 76114:EB_RS18195
uniprot id: Q5NYL6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS19060
gene id: 76114:EB_RS19060
uniprot id: Q5NY30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

76114:EB RS15005
gene id: 76114:EB_RS15005
uniprot id: Q5P0I0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS19445
gene id: 76114:EB_RS19445
uniprot id: Q5NXV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

76114:EB RS08840
gene id: 76114:EB_RS08840
uniprot id: Q5P453
names: Similarity
messages: Belongs to the leucine-binding protein family.

76114:EB RS10680
gene id: 76114:EB_RS10680
uniprot id: Q5P310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

76114:EB RS17085
gene id: 76114:EB_RS17085
uniprot id: Q5NZ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS12030
gene id: 76114:EB_RS12030
uniprot id: Q5P286
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

76114:EB RS06395
gene id: 76114:EB_RS06395
uniprot id: Q5P5K8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS10585
gene id: 76114:EB_RS10585
uniprot id: Q5P329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

76114:EB RS08235
gene id: 76114:EB_RS08235
uniprot id: Q5P4H2
names: Similarity
messages: Belongs to the Smg family.

76114:EB RS02230
gene id: 76114:EB_RS02230
uniprot id: Q5P7Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

76114:EB RS19870
gene id: 76114:EB_RS19870
uniprot id: Q5NXM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

76114:EB RS17715
gene id: 76114:EB_RS17715
uniprot id: Q5NYW8
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

76114:EB RS05440
gene id: 76114:EB_RS05440
uniprot id: Q5P659
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS04735
gene id: 76114:EB_RS04735
uniprot id: Q5P6K8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS07405
gene id: 76114:EB_RS07405
uniprot id: Q5P4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

76114:EB RS02970
gene id: 76114:EB_RS02970
uniprot id: Q5P7K7
names: Similarity
messages: Belongs to the pyruvate kinase family.

76114:EB RS12580
gene id: 76114:EB_RS12580
uniprot id: Q5P1X9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

76114:EB RS18890
gene id: 76114:EB_RS18890
uniprot id: Q5NY65
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

76114:EB RS03820
gene id: 76114:EB_RS03820
uniprot id: Q5P739
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

76114:EB RS04995
gene id: 76114:EB_RS04995
uniprot id: Q5P6F5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

76114:EB RS05255
gene id: 76114:EB_RS05255
uniprot id: Q5P6A0
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

76114:EB RS04110
gene id: 76114:EB_RS04110
uniprot id: Q5P6Y3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

76114:EB RS12290
gene id: 76114:EB_RS12290
uniprot id: Q5P234
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

76114:EB RS11060
gene id: 76114:EB_RS11060
uniprot id: Q5P2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS13380
gene id: 76114:EB_RS13380
uniprot id: Q5P1G5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

76114:EB RS03145
gene id: 76114:EB_RS03145
uniprot id: Q5P7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

76114:EB RS11290
gene id: 76114:EB_RS11290
uniprot id: Q5P2N3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS17645
gene id: 76114:EB_RS17645
uniprot id: Q5NYY1
names: Similarity
messages: Belongs to the UPF0178 family.

76114:EB RS02140
gene id: 76114:EB_RS02140
uniprot id: Q5P814
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS22935
gene id: 76114:EB_RS22935
uniprot id: Q5P8G0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

76114:EB RS09100
gene id: 76114:EB_RS09100
uniprot id: Q5P3Y5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

76114:EB RS02215
gene id: 76114:EB_RS02215
uniprot id: Q5P7Z9
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

76114:EB RS10510
gene id: 76114:EB_RS10510
uniprot id: Q5P344
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

76114:EB RS16720
gene id: 76114:EB_RS16720
uniprot id: Q5NZH8
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

76114:EB RS04480
gene id: 76114:EB_RS04480
uniprot id: Q5P6Q8
names: Similarity
messages: Belongs to the GSP I family.

76114:EB RS11680
gene id: 76114:EB_RS11680
uniprot id: Q5P2G0
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS07385
gene id: 76114:EB_RS07385
uniprot id: Q5P500
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

76114:EB RS09065
gene id: 76114:EB_RS09065
uniprot id: Q5P3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

76114:EB RS22410
gene id: 76114:EB_RS22410
uniprot id: Q5NW46
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS19350
gene id: 76114:EB_RS19350
uniprot id: Q5NXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

76114:EB RS03265
gene id: 76114:EB_RS03265
uniprot id: Q5P7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

76114:EB RS17570
gene id: 76114:EB_RS17570
uniprot id: Q5NYZ7
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS06400
gene id: 76114:EB_RS06400
uniprot id: Q5P5K7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS10650
gene id: 76114:EB_RS10650
uniprot id: Q5P316
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

76114:EB RS16170
gene id: 76114:EB_RS16170
uniprot id: Q5NZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

76114:EB RS02780
gene id: 76114:EB_RS02780
uniprot id: Q5P7P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS19205
gene id: 76114:EB_RS19205
uniprot id: Q5NY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

76114:EB RS12115
gene id: 76114:EB_RS12115
uniprot id: Q5P269
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

76114:EB RS13500
gene id: 76114:EB_RS13500
uniprot id: Q5P1E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS06260
gene id: 76114:EB_RS06260
uniprot id: Q5P5N6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

76114:EB RS14880
gene id: 76114:EB_RS14880
uniprot id: Q5P0K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS18560
gene id: 76114:EB_RS18560
uniprot id: Q5NYE2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

76114:EB RS13890
gene id: 76114:EB_RS13890
uniprot id: Q5P161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

76114:EB RS11175
gene id: 76114:EB_RS11175
uniprot id: Q5P2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

76114:EB RS11305
gene id: 76114:EB_RS11305
uniprot id: Q5P2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

76114:EB RS01755
gene id: 76114:EB_RS01755
uniprot id: Q5P892
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

76114:EB RS16175
gene id: 76114:EB_RS16175
uniprot id: Q5NZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

76114:EB RS00540
gene id: 76114:EB_RS00540
uniprot id: Q5P8Y2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS07555
gene id: 76114:EB_RS07555
uniprot id: Q5P4W9
names: Similarity
messages: Belongs to the leucine-binding protein family.

76114:EB RS08830
gene id: 76114:EB_RS08830
uniprot id: Q5P455
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS06195
gene id: 76114:EB_RS06195
uniprot id: Q5P5P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

76114:EB RS13110
gene id: 76114:EB_RS13110
uniprot id: Q5P1L5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS13210
gene id: 76114:EB_RS13210
uniprot id: Q5P1K0
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS06910
gene id: 76114:EB_RS06910
uniprot id: Q5P5A5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

76114:EB RS13710
gene id: 76114:EB_RS13710
uniprot id: Q5P199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS09700
gene id: 76114:EB_RS09700
uniprot id: Q5P3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

76114:EB RS07415
gene id: 76114:EB_RS07415
uniprot id: Q5P4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

76114:EB RS18485
gene id: 76114:EB_RS18485
uniprot id: Q5NYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26C family.
messages: Periplasm

76114:EB RS00760
gene id: 76114:EB_RS00760
uniprot id: Q5P8U0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

76114:EB RS03170
gene id: 76114:EB_RS03170
uniprot id: Q5P7G9
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

76114:EB RS10015
gene id: 76114:EB_RS10015
uniprot id: Q5P3E2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

76114:EB RS08665
gene id: 76114:EB_RS08665
uniprot id: Q5P490
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

76114:EB RS21825
gene id: 76114:EB_RS21825
uniprot id: Q5NWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS04140
gene id: 76114:EB_RS04140
uniprot id: Q5P6X7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

76114:EB RS02590
gene id: 76114:EB_RS02590
uniprot id: Q5P7T2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

76114:EB RS19925
gene id: 76114:EB_RS19925
uniprot id: Q5NXL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

76114:EB RS16470
gene id: 76114:EB_RS16470
uniprot id: Q5NZM8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS10660
gene id: 76114:EB_RS10660
uniprot id: Q5P314
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

76114:EB RS21930
gene id: 76114:EB_RS21930
uniprot id: Q5NWF3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS11335
gene id: 76114:EB_RS11335
uniprot id: Q5P2M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

76114:EB RS04070
gene id: 76114:EB_RS04070
uniprot id: Q5P6Z1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS05195
gene id: 76114:EB_RS05195
uniprot id: Q5P6B2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS04055
gene id: 76114:EB_RS04055
uniprot id: Q5P6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

76114:EB RS05135
gene id: 76114:EB_RS05135
uniprot id: Q5P6C5
names: Similarity
messages: Belongs to the UPF0423 family.

76114:EB RS15000
gene id: 76114:EB_RS15000
uniprot id: Q5P0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

76114:EB RS08015
gene id: 76114:EB_RS08015
uniprot id: Q5P4L5
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

76114:EB RS07615
gene id: 76114:EB_RS07615
uniprot id: Q5P4V7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

76114:EB RS13105
gene id: 76114:EB_RS13105
uniprot id: Q5P1L7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS13495
gene id: 76114:EB_RS13495
uniprot id: Q5P1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

76114:EB RS00430
gene id: 76114:EB_RS00430
uniprot id: Q5P904
names: Similarity
messages: Belongs to the TPP enzyme family.

76114:EB RS15170
gene id: 76114:EB_RS15170
uniprot id: Q5P0E8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

76114:EB RS09985
gene id: 76114:EB_RS09985
uniprot id: Q5P3E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS03205
gene id: 76114:EB_RS03205
uniprot id: Q5P7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

76114:EB RS03270
gene id: 76114:EB_RS03270
uniprot id: Q5P7E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

76114:EB RS17115
gene id: 76114:EB_RS17115
uniprot id: Q5NZ92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

76114:EB RS17190
gene id: 76114:EB_RS17190
uniprot id: Q5NZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS03420
gene id: 76114:EB_RS03420
uniprot id: Q5P7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

76114:EB RS13645
gene id: 76114:EB_RS13645
uniprot id: Q5P1B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS02760
gene id: 76114:EB_RS02760
uniprot id: Q5P7P8
names: Similarity
messages: Belongs to the UPF0307 family.

76114:EB RS04045
gene id: 76114:EB_RS04045
uniprot id: Q5P6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

76114:EB RS02955
gene id: 76114:EB_RS02955
uniprot id: Q5P7L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

76114:EB RS12280
gene id: 76114:EB_RS12280
uniprot id: Q5P236
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

76114:EB RS16740
gene id: 76114:EB_RS16740
uniprot id: Q5NZH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

76114:EB RS16280
gene id: 76114:EB_RS16280
uniprot id: Q5NZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

76114:EB RS11850
gene id: 76114:EB_RS11850
uniprot id: Q5P2C5
names: Similarity
messages: Belongs to the asparagine synthetase family.

76114:EB RS03015
gene id: 76114:EB_RS03015
uniprot id: Q5P7J7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

76114:EB RS18345
gene id: 76114:EB_RS18345
uniprot id: Q5NYI5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS11000
gene id: 76114:EB_RS11000
uniprot id: Q5P2U5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS04935
gene id: 76114:EB_RS04935
uniprot id: Q5P6G8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

76114:EB RS17885
gene id: 76114:EB_RS17885
uniprot id: Q5NYT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

76114:EB RS12520
gene id: 76114:EB_RS12520
uniprot id: Q5P1Y9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

76114:EB RS02805
gene id: 76114:EB_RS02805
uniprot id: Q5P7N9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

76114:EB RS12480
gene id: 76114:EB_RS12480
uniprot id: Q5P1Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

76114:EB RS09595
gene id: 76114:EB_RS09595
uniprot id: Q5P3M9
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS16890
gene id: 76114:EB_RS16890
uniprot id: Q5NZE1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

76114:EB RS21460
gene id: 76114:EB_RS21460
uniprot id: Q5NWM6
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS00390
gene id: 76114:EB_RS00390
uniprot id: Q5P914
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

76114:EB RS16815
gene id: 76114:EB_RS16815
uniprot id: Q5NZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS16790
gene id: 76114:EB_RS16790
uniprot id: Q5NZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

76114:EB RS19680
gene id: 76114:EB_RS19680
uniprot id: Q5NXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

76114:EB RS13490
gene id: 76114:EB_RS13490
uniprot id: Q5P1E4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS15045
gene id: 76114:EB_RS15045
uniprot id: Q5P0H2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

76114:EB RS03565
gene id: 76114:EB_RS03565
uniprot id: Q5P791
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

76114:EB RS02505
gene id: 76114:EB_RS02505
uniprot id: Q5P7U3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

76114:EB RS08355
gene id: 76114:EB_RS08355
uniprot id: Q5P4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

76114:EB RS06285
gene id: 76114:EB_RS06285
uniprot id: Q5P5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

76114:EB RS01435
gene id: 76114:EB_RS01435
uniprot id: Q5P8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

76114:EB RS09370
gene id: 76114:EB_RS09370
uniprot id: Q5P3S7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

76114:EB RS13225
gene id: 76114:EB_RS13225
uniprot id: Q5P1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

76114:EB RS06010
gene id: 76114:EB_RS06010
uniprot id: Q5P5T8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

76114:EB RS19605
gene id: 76114:EB_RS19605
uniprot id: Q5NXS8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

76114:EB RS08320
gene id: 76114:EB_RS08320
uniprot id: Q5P4F3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS02435
gene id: 76114:EB_RS02435
uniprot id: Q5P7V7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

76114:EB RS22390
gene id: 76114:EB_RS22390
uniprot id: Q5NW51
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS09330
gene id: 76114:EB_RS09330
uniprot id: Q5P3T5
names: Subcellular Location Annotation
messages: Mitochondrion

76114:EB RS02480
gene id: 76114:EB_RS02480
uniprot id: Q5P7U8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

76114:EB RS19150
gene id: 76114:EB_RS19150
uniprot id: Q5NY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS06340
gene id: 76114:EB_RS06340
uniprot id: Q5P5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

76114:EB RS12950
gene id: 76114:EB_RS12950
uniprot id: Q5P1Q0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

76114:EB RS02020
gene id: 76114:EB_RS02020
uniprot id: Q5P837
names: Similarity
messages: Belongs to the histone deacetylase family.

76114:EB RS19875
gene id: 76114:EB_RS19875
uniprot id: Q5NXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

76114:EB RS10630
gene id: 76114:EB_RS10630
uniprot id: Q5P320
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

76114:EB RS11330
gene id: 76114:EB_RS11330
uniprot id: Q5P2M5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

76114:EB RS04085
gene id: 76114:EB_RS04085
uniprot id: Q5P6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

76114:EB RS10765
gene id: 76114:EB_RS10765
uniprot id: Q5P2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

76114:EB RS06425
gene id: 76114:EB_RS06425
uniprot id: Q5P5K2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS02850
gene id: 76114:EB_RS02850
uniprot id: Q5P7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

76114:EB RS19700
gene id: 76114:EB_RS19700
uniprot id: Q5NXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

76114:EB RS13315
gene id: 76114:EB_RS13315
uniprot id: Q5P1H8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

76114:EB RS10180
gene id: 76114:EB_RS10180
uniprot id: Q5P3A9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS03895
gene id: 76114:EB_RS03895
uniprot id: Q5P725
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

76114:EB RS03480
gene id: 76114:EB_RS03480
uniprot id: Q5P7A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

76114:EB RS12250
gene id: 76114:EB_RS12250
uniprot id: Q5P243
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

76114:EB RS08780
gene id: 76114:EB_RS08780
uniprot id: Q5P466
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

76114:EB RS07860
gene id: 76114:EB_RS07860
uniprot id: Q5P4Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

76114:EB RS15145
gene id: 76114:EB_RS15145
uniprot id: Q5P0F1
names: Similarity
messages: Belongs to the peptidase S16 family.

76114:EB RS18335
gene id: 76114:EB_RS18335
uniprot id: Q5NYI8
names: Similarity
messages: Belongs to the fructosamine kinase family.

76114:EB RS05495
gene id: 76114:EB_RS05495
uniprot id: Q5P648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

76114:EB RS16820
gene id: 76114:EB_RS16820
uniprot id: Q5NZF7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

76114:EB RS05565
gene id: 76114:EB_RS05565
uniprot id: Q5P634
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

76114:EB RS09525
gene id: 76114:EB_RS09525
uniprot id: Q5P3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

76114:EB RS04160
gene id: 76114:EB_RS04160
uniprot id: Q5P6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

76114:EB RS19235
gene id: 76114:EB_RS19235
uniprot id: Q5NXZ7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

76114:EB RS09705
gene id: 76114:EB_RS09705
uniprot id: Q5P3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

76114:EB RS14200
gene id: 76114:EB_RS14200
uniprot id: Q5P0Z9
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

76114:EB RS00890
gene id: 76114:EB_RS00890
uniprot id: Q5P8R5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03845
gene id: 76114:EB_RS03845
uniprot id: Q5P734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

76114:EB RS06465
gene id: 76114:EB_RS06465
uniprot id: Q5P5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

76114:EB RS12155
gene id: 76114:EB_RS12155
uniprot id: Q5P261
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

76114:EB RS10620
gene id: 76114:EB_RS10620
uniprot id: Q5P322
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

76114:EB RS09645
gene id: 76114:EB_RS09645
uniprot id: Q5P3L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

76114:EB RS02635
gene id: 76114:EB_RS02635
uniprot id: Q5P7S3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

76114:EB RS03525
gene id: 76114:EB_RS03525
uniprot id: Q5P799
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

76114:EB RS17980
gene id: 76114:EB_RS17980
uniprot id: Q5NYR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

76114:EB RS17550
gene id: 76114:EB_RS17550
uniprot id: Q5NZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

76114:EB RS09735
gene id: 76114:EB_RS09735
uniprot id: Q5P3K0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

76114:EB RS20030
gene id: 76114:EB_RS20030
uniprot id: Q5NXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

76114:EB RS16745
gene id: 76114:EB_RS16745
uniprot id: Q5NZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

76114:EB RS15785
gene id: 76114:EB_RS15785
uniprot id: Q5P018
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS08455
gene id: 76114:EB_RS08455
uniprot id: Q5P4C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

76114:EB RS13345
gene id: 76114:EB_RS13345
uniprot id: Q5P1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

76114:EB RS16210
gene id: 76114:EB_RS16210
uniprot id: Q5NZS9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

76114:EB RS11230
gene id: 76114:EB_RS11230
uniprot id: Q5P2P5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS03570
gene id: 76114:EB_RS03570
uniprot id: Q5P790
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

76114:EB RS08685
gene id: 76114:EB_RS08685
uniprot id: Q5P485
names: Similarity
messages: Belongs to the Nudix hydrolase family.

76114:EB RS02235
gene id: 76114:EB_RS02235
uniprot id: Q5P7Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

76114:EB RS04500
gene id: 76114:EB_RS04500
uniprot id: Q5P6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

76114:EB RS08270
gene id: 76114:EB_RS08270
uniprot id: Q5P4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

76114:EB RS08695
gene id: 76114:EB_RS08695
uniprot id: Q5P483
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS11655
gene id: 76114:EB_RS11655
uniprot id: Q5P2G5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

76114:EB RS06205
gene id: 76114:EB_RS06205
uniprot id: Q5P5P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

76114:EB RS02905
gene id: 76114:EB_RS02905
uniprot id: Q5P7M0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

76114:EB RS11350
gene id: 76114:EB_RS11350
uniprot id: Q5P2M1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

76114:EB RS18150
gene id: 76114:EB_RS18150
uniprot id: Q5NYM5
names: Similarity
messages: Belongs to the YciI family.

76114:EB RS01445
gene id: 76114:EB_RS01445
uniprot id: Q5P8E9
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS13940
gene id: 76114:EB_RS13940
uniprot id: Q5P152
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS01440
gene id: 76114:EB_RS01440
uniprot id: Q5P8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

76114:EB RS05845
gene id: 76114:EB_RS05845
uniprot id: Q5P5X6
names: Similarity
messages: Belongs to the catalase family.

76114:EB RS23250
gene id: 76114:EB_RS23250
uniprot id: Q5P4P1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

76114:EB RS12690
gene id: 76114:EB_RS12690
uniprot id: Q5P1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

76114:EB RS17480
gene id: 76114:EB_RS17480
uniprot id: Q5NZ16
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS15555
gene id: 76114:EB_RS15555
uniprot id: Q5P070
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS16805
gene id: 76114:EB_RS16805
uniprot id: Q5NZG0
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS08370
gene id: 76114:EB_RS08370
uniprot id: Q5P4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

76114:EB RS07240
gene id: 76114:EB_RS07240
uniprot id: Q5P534
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS09785
gene id: 76114:EB_RS09785
uniprot id: Q5P3J0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

76114:EB RS00345
gene id: 76114:EB_RS00345
uniprot id: Q5P923
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

76114:EB RS14685
gene id: 76114:EB_RS14685
uniprot id: Q5P0P7
names: Similarity
messages: Belongs to the asparagine synthetase family.

76114:EB RS19620
gene id: 76114:EB_RS19620
uniprot id: Q5NXS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS15480
gene id: 76114:EB_RS15480
uniprot id: Q5P086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

76114:EB RS08385
gene id: 76114:EB_RS08385
uniprot id: Q5P4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

76114:EB RS13535
gene id: 76114:EB_RS13535
uniprot id: Q5P1D5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

76114:EB RS01540
gene id: 76114:EB_RS01540
uniprot id: Q5P8D0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

76114:EB RS00340
gene id: 76114:EB_RS00340
uniprot id: Q5P924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

76114:EB RS15680
gene id: 76114:EB_RS15680
uniprot id: Q5P040
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS02725
gene id: 76114:EB_RS02725
uniprot id: Q5P7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

76114:EB RS16245
gene id: 76114:EB_RS16245
uniprot id: Q5NZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

76114:EB RS17840
gene id: 76114:EB_RS17840
uniprot id: Q5NYT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

76114:EB RS13235
gene id: 76114:EB_RS13235
uniprot id: Q5P1J5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS03260
gene id: 76114:EB_RS03260
uniprot id: Q5P7F1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

76114:EB RS06220
gene id: 76114:EB_RS06220
uniprot id: Q5P5P4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

76114:EB RS02220
gene id: 76114:EB_RS02220
uniprot id: Q5P7Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS06415
gene id: 76114:EB_RS06415
uniprot id: Q5P5K4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

76114:EB RS19695
gene id: 76114:EB_RS19695
uniprot id: Q5NXR1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS03850
gene id: 76114:EB_RS03850
uniprot id: Q5P733
names: Similarity
messages: Belongs to the peptidase M16 family.

76114:EB RS12060
gene id: 76114:EB_RS12060
uniprot id: Q5P280
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS12545
gene id: 76114:EB_RS12545
uniprot id: Q5P1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

76114:EB RS13285
gene id: 76114:EB_RS13285
uniprot id: Q5P1I5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS15210
gene id: 76114:EB_RS15210
uniprot id: Q5P0D9
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

76114:EB RS03100
gene id: 76114:EB_RS03100
uniprot id: Q5P7I2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

76114:EB RS02175
gene id: 76114:EB_RS02175
uniprot id: Q5P807
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS11440
gene id: 76114:EB_RS11440
uniprot id: Q5P2K9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

76114:EB RS10060
gene id: 76114:EB_RS10060
uniprot id: Q5P3D1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS06515
gene id: 76114:EB_RS06515
uniprot id: Q5P5I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS14975
gene id: 76114:EB_RS14975
uniprot id: Q5P0I6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS10940
gene id: 76114:EB_RS10940
uniprot id: Q5P2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS04900
gene id: 76114:EB_RS04900
uniprot id: Q5P6H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

76114:EB RS10635
gene id: 76114:EB_RS10635
uniprot id: Q5P319
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

76114:EB RS07915
gene id: 76114:EB_RS07915
uniprot id: Q5P4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

76114:EB RS11595
gene id: 76114:EB_RS11595
uniprot id: Q5P2H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

76114:EB RS16200
gene id: 76114:EB_RS16200
uniprot id: Q5NZT1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

76114:EB RS08690
gene id: 76114:EB_RS08690
uniprot id: Q5P484
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.

76114:EB RS22505
gene id: 76114:EB_RS22505
uniprot id: Q5P7Q7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

76114:EB RS18270
gene id: 76114:EB_RS18270
uniprot id: Q5NYK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

76114:EB RS08250
gene id: 76114:EB_RS08250
uniprot id: Q5P4G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS18800
gene id: 76114:EB_RS18800
uniprot id: Q5NY86
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

76114:EB RS13250
gene id: 76114:EB_RS13250
uniprot id: Q5P1J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

76114:EB RS01635
gene id: 76114:EB_RS01635
uniprot id: Q5P8B4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

76114:EB RS09585
gene id: 76114:EB_RS09585
uniprot id: Q5P3N1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

76114:EB RS16990
gene id: 76114:EB_RS16990
uniprot id: Q5NZC0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

76114:EB RS03615
gene id: 76114:EB_RS03615
uniprot id: Q5P781
names: Similarity
messages: Belongs to the MlaA family.

76114:EB RS17345
gene id: 76114:EB_RS17345
uniprot id: Q5NZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

76114:EB RS03880
gene id: 76114:EB_RS03880
uniprot id: Q5P728
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

76114:EB RS15230
gene id: 76114:EB_RS15230
uniprot id: Q5P0D5
names: Similarity
messages: Belongs to the fabD family.

76114:EB RS18670
gene id: 76114:EB_RS18670
uniprot id: Q5NYB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

76114:EB RS18265
gene id: 76114:EB_RS18265
uniprot id: Q5NYK1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

76114:EB RS15495
gene id: 76114:EB_RS15495
uniprot id: Q5P083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

76114:EB RS03705
gene id: 76114:EB_RS03705
uniprot id: Q5P762
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

76114:EB RS16775
gene id: 76114:EB_RS16775
uniprot id: Q5NZG6
names: Similarity
messages: Belongs to the skp family.

76114:EB RS10435
gene id: 76114:EB_RS10435
uniprot id: Q5P355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

76114:EB RS14145
gene id: 76114:EB_RS14145
uniprot id: Q5P110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

76114:EB RS10160
gene id: 76114:EB_RS10160
uniprot id: Q5P3B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

76114:EB RS12650
gene id: 76114:EB_RS12650
uniprot id: Q5P1W3
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

76114:EB RS10525
gene id: 76114:EB_RS10525
uniprot id: Q5P341
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

76114:EB RS16635
gene id: 76114:EB_RS16635
uniprot id: Q5NZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS08715
gene id: 76114:EB_RS08715
uniprot id: Q5P479
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

76114:EB RS03915
gene id: 76114:EB_RS03915
uniprot id: Q5P722
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

76114:EB RS04280
gene id: 76114:EB_RS04280
uniprot id: Q5P6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

76114:EB RS09690
gene id: 76114:EB_RS09690
uniprot id: Q5P3K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

76114:EB RS03635
gene id: 76114:EB_RS03635
uniprot id: Q5P777
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

76114:EB RS09710
gene id: 76114:EB_RS09710
uniprot id: Q5P3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS08365
gene id: 76114:EB_RS08365
uniprot id: Q5P4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

76114:EB RS05085
gene id: 76114:EB_RS05085
uniprot id: Q5P6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

76114:EB RS02335
gene id: 76114:EB_RS02335
uniprot id: Q5P7X7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

76114:EB RS17975
gene id: 76114:EB_RS17975
uniprot id: Q5NYR2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS06110
gene id: 76114:EB_RS06110
uniprot id: Q5P5R8
names: Similarity
messages: Belongs to the MlaA family.

76114:EB RS08825
gene id: 76114:EB_RS08825
uniprot id: Q5P456
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS13305
gene id: 76114:EB_RS13305
uniprot id: Q5P1I1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

76114:EB RS03505
gene id: 76114:EB_RS03505
uniprot id: Q5P7A3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

76114:EB RS06280
gene id: 76114:EB_RS06280
uniprot id: Q5P5N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

76114:EB RS03575
gene id: 76114:EB_RS03575
uniprot id: Q5P789
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

76114:EB RS09975
gene id: 76114:EB_RS09975
uniprot id: Q5P3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

76114:EB RS13325
gene id: 76114:EB_RS13325
uniprot id: Q5P1H5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

76114:EB RS18565
gene id: 76114:EB_RS18565
uniprot id: Q5NYE1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

76114:EB RS05695
gene id: 76114:EB_RS05695
uniprot id: Q5P607
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS07610
gene id: 76114:EB_RS07610
uniprot id: Q5P4V8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

76114:EB RS10175
gene id: 76114:EB_RS10175
uniprot id: Q5P3B0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

76114:EB RS08210
gene id: 76114:EB_RS08210
uniprot id: Q5P4H7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

76114:EB RS18235
gene id: 76114:EB_RS18235
uniprot id: Q5NYK8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

76114:EB RS18920
gene id: 76114:EB_RS18920
uniprot id: Q5NY58
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

76114:EB RS03430
gene id: 76114:EB_RS03430
uniprot id: Q5P7B7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

76114:EB RS16215
gene id: 76114:EB_RS16215
uniprot id: Q5NZS8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

76114:EB RS11645
gene id: 76114:EB_RS11645
uniprot id: Q5P2G7
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS09430
gene id: 76114:EB_RS09430
uniprot id: Q5P3R5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

76114:EB RS01520
gene id: 76114:EB_RS01520
uniprot id: Q5P8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

76114:EB RS11690
gene id: 76114:EB_RS11690
uniprot id: Q5P2F8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

76114:EB RS11345
gene id: 76114:EB_RS11345
uniprot id: Q5P2M2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

76114:EB RS14220
gene id: 76114:EB_RS14220
uniprot id: Q5P0Z5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

76114:EB RS08520
gene id: 76114:EB_RS08520
uniprot id: Q5P4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

76114:EB RS13650
gene id: 76114:EB_RS13650
uniprot id: Q5P1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS19260
gene id: 76114:EB_RS19260
uniprot id: Q5NXZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

76114:EB RS02975
gene id: 76114:EB_RS02975
uniprot id: Q5P7K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

76114:EB RS03180
gene id: 76114:EB_RS03180
uniprot id: Q5P7G7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

76114:EB RS11725
gene id: 76114:EB_RS11725
uniprot id: Q5P2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

76114:EB RS12195
gene id: 76114:EB_RS12195
uniprot id: Q5P253
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

76114:EB RS11295
gene id: 76114:EB_RS11295
uniprot id: Q5P2N2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

76114:EB RS13845
gene id: 76114:EB_RS13845
uniprot id: Q5P171
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS12175
gene id: 76114:EB_RS12175
uniprot id: Q5P257
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

76114:EB RS18715
gene id: 76114:EB_RS18715
uniprot id: Q5NYA9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

76114:EB RS02785
gene id: 76114:EB_RS02785
uniprot id: Q5P7P3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

76114:EB RS17810
gene id: 76114:EB_RS17810
uniprot id: Q5NYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

76114:EB RS06325
gene id: 76114:EB_RS06325
uniprot id: Q5P5M2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

76114:EB RS13625
gene id: 76114:EB_RS13625
uniprot id: Q5P1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS03645
gene id: 76114:EB_RS03645
uniprot id: Q5P775
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

76114:EB RS06040
gene id: 76114:EB_RS06040
uniprot id: Q5P5T2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS19880
gene id: 76114:EB_RS19880
uniprot id: Q5NXM4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

76114:EB RS12340
gene id: 76114:EB_RS12340
uniprot id: Q5P229
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

76114:EB RS15940
gene id: 76114:EB_RS15940
uniprot id: Q5NZY6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

76114:EB RS03225
gene id: 76114:EB_RS03225
uniprot id: Q5P7F8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

76114:EB RS07920
gene id: 76114:EB_RS07920
uniprot id: Q5P4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

76114:EB RS00135
gene id: 76114:EB_RS00135
uniprot id: Q5P972
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

76114:EB RS18115
gene id: 76114:EB_RS18115
uniprot id: Q5NYN2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

76114:EB RS13735
gene id: 76114:EB_RS13735
uniprot id: Q5P194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

76114:EB RS09320
gene id: 76114:EB_RS09320
uniprot id: Q5P3T7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

76114:EB RS02865
gene id: 76114:EB_RS02865
uniprot id: Q5P7M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

76114:EB RS15085
gene id: 76114:EB_RS15085
uniprot id: Q5P0G4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

76114:EB RS12420
gene id: 76114:EB_RS12420
uniprot id: Q5P212
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

76114:EB RS05175
gene id: 76114:EB_RS05175
uniprot id: Q5P6B6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

76114:EB RS19835
gene id: 76114:EB_RS19835
uniprot id: Q5NXN4
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS16480
gene id: 76114:EB_RS16480
uniprot id: Q5NZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS12365
gene id: 76114:EB_RS12365
uniprot id: Q5P224
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

76114:EB RS15515
gene id: 76114:EB_RS15515
uniprot id: Q5P079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

76114:EB RS18855
gene id: 76114:EB_RS18855
uniprot id: Q5NY72
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS17205
gene id: 76114:EB_RS17205
uniprot id: Q5NZ74
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

76114:EB RS14135
gene id: 76114:EB_RS14135
uniprot id: Q5P113
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

76114:EB RS17430
gene id: 76114:EB_RS17430
uniprot id: Q5NZ26
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

76114:EB RS09535
gene id: 76114:EB_RS09535
uniprot id: Q5P3P3
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS06190
gene id: 76114:EB_RS06190
uniprot id: Q5P5Q0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS07365
gene id: 76114:EB_RS07365
uniprot id: Q5P504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

76114:EB RS20425
gene id: 76114:EB_RS20425
uniprot id: Q5NXB1
names: Similarity
messages: Belongs to the ParB family.

76114:EB RS13420
gene id: 76114:EB_RS13420
uniprot id: Q5P1F7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

76114:EB RS01555
gene id: 76114:EB_RS01555
uniprot id: Q5P8C7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

76114:EB RS02540
gene id: 76114:EB_RS02540
uniprot id: Q5P7U1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS09715
gene id: 76114:EB_RS09715
uniprot id: Q5P3K4
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

76114:EB RS19435
gene id: 76114:EB_RS19435
uniprot id: Q5NXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

76114:EB RS17630
gene id: 76114:EB_RS17630
uniprot id: Q5NYY5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

76114:EB RS11055
gene id: 76114:EB_RS11055
uniprot id: Q5P2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

76114:EB RS11430
gene id: 76114:EB_RS11430
uniprot id: Q5P2L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS03105
gene id: 76114:EB_RS03105
uniprot id: Q5P7I1
names: Similarity
messages: Belongs to the GARS family.

76114:EB RS01980
gene id: 76114:EB_RS01980
uniprot id: Q5P070
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS19025
gene id: 76114:EB_RS19025
uniprot id: Q5NY38
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

76114:EB RS16355
gene id: 76114:EB_RS16355
uniprot id: Q5NZQ1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

76114:EB RS16840
gene id: 76114:EB_RS16840
uniprot id: Q5NZF3
names: Similarity
messages: Belongs to the UPF0246 family.

76114:EB RS17220
gene id: 76114:EB_RS17220
uniprot id: Q5NZ71
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

76114:EB RS02240
gene id: 76114:EB_RS02240
uniprot id: Q5P7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

76114:EB RS07800
gene id: 76114:EB_RS07800
uniprot id: Q5P4R7
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS09925
gene id: 76114:EB_RS09925
uniprot id: Q5P3G0
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

76114:EB RS01740
gene id: 76114:EB_RS01740
uniprot id: Q5P895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

76114:EB RS06365
gene id: 76114:EB_RS06365
uniprot id: Q5P5L4
names: Similarity
messages: Belongs to the pirin family.

76114:EB RS17035
gene id: 76114:EB_RS17035
uniprot id: Q5NZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS12035
gene id: 76114:EB_RS12035
uniprot id: Q5P285
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

76114:EB RS10515
gene id: 76114:EB_RS10515
uniprot id: Q5P343
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

76114:EB RS13295
gene id: 76114:EB_RS13295
uniprot id: Q5P1I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

76114:EB RS12350
gene id: 76114:EB_RS12350
uniprot id: Q5P227
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

76114:EB RS17240
gene id: 76114:EB_RS17240
uniprot id: Q5NZ67
names: Similarity
messages: Belongs to the peptidase C40 family.

76114:EB RS08405
gene id: 76114:EB_RS08405
uniprot id: Q5P4D6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

76114:EB RS18145
gene id: 76114:EB_RS18145
uniprot id: Q5NYM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

76114:EB RS14020
gene id: 76114:EB_RS14020
uniprot id: Q5P137
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS16885
gene id: 76114:EB_RS16885
uniprot id: Q5NZE2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

76114:EB RS14470
gene id: 76114:EB_RS14470
uniprot id: Q5P0U5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03560
gene id: 76114:EB_RS03560
uniprot id: Q5P792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

76114:EB RS20055
gene id: 76114:EB_RS20055
uniprot id: Q5NXI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

76114:EB RS07850
gene id: 76114:EB_RS07850
uniprot id: Q5P4Q7
names: Subcellular Location Annotation
messages: Nucleus

76114:EB RS04870
gene id: 76114:EB_RS04870
uniprot id: Q5P6I1
names: Similarity
messages: Belongs to the YggT family.

76114:EB RS02560
gene id: 76114:EB_RS02560
uniprot id: Q5P7T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

76114:EB RS13275
gene id: 76114:EB_RS13275
uniprot id: Q5P1I7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

76114:EB RS12075
gene id: 76114:EB_RS12075
uniprot id: Q5P277
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

76114:EB RS03375
gene id: 76114:EB_RS03375
uniprot id: Q5P7C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

76114:EB RS16710
gene id: 76114:EB_RS16710
uniprot id: Q5NZH9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

76114:EB RS04075
gene id: 76114:EB_RS04075
uniprot id: Q5P6Z0
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

76114:EB RS03585
gene id: 76114:EB_RS03585
uniprot id: Q5P787
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

76114:EB RS02245
gene id: 76114:EB_RS02245
uniprot id: Q5P7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

76114:EB RS10720
gene id: 76114:EB_RS10720
uniprot id: Q5P300
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

76114:EB RS15835
gene id: 76114:EB_RS15835
uniprot id: Q5P007
names: Similarity
messages: Belongs to the TPP enzyme family.

76114:EB RS03590
gene id: 76114:EB_RS03590
uniprot id: Q5P786
names: Similarity
messages: Belongs to the BolA/IbaG family.

76114:EB RS06350
gene id: 76114:EB_RS06350
uniprot id: Q5P5L7
names: Similarity
messages: Belongs to the RutC family.

76114:EB RS03135
gene id: 76114:EB_RS03135
uniprot id: Q5P7H5
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

76114:EB RS04205
gene id: 76114:EB_RS04205
uniprot id: Q5P6W3
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS12265
gene id: 76114:EB_RS12265
uniprot id: Q5P239
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

76114:EB RS20640
gene id: 76114:EB_RS20640
uniprot id: Q5NX65
names: Similarity
messages: Belongs to the type IA topoisomerase family.

76114:EB RS03210
gene id: 76114:EB_RS03210
uniprot id: Q5P7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

76114:EB RS17525
gene id: 76114:EB_RS17525
uniprot id: Q5NZ06
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03510
gene id: 76114:EB_RS03510
uniprot id: Q5P7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

76114:EB RS21820
gene id: 76114:EB_RS21820
uniprot id: Q5NWF9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

76114:EB RS13205
gene id: 76114:EB_RS13205
uniprot id: Q5P1K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

76114:EB RS02205
gene id: 76114:EB_RS02205
uniprot id: Q5P801
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

76114:EB RS08865
gene id: 76114:EB_RS08865
uniprot id: Q5P447
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS12855
gene id: 76114:EB_RS12855
uniprot id: Q5P1R9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS13100
gene id: 76114:EB_RS13100
uniprot id: Q5P1L8
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS16835
gene id: 76114:EB_RS16835
uniprot id: Q5NZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS12465
gene id: 76114:EB_RS12465
uniprot id: Q5P201
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

76114:EB RS04255
gene id: 76114:EB_RS04255
uniprot id: Q5P6V4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

76114:EB RS17305
gene id: 76114:EB_RS17305
uniprot id: Q5NZ54
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS17655
gene id: 76114:EB_RS17655
uniprot id: Q5NYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Cell inner membrane
messages: Multidrug efflux pump.

76114:EB RS04865
gene id: 76114:EB_RS04865
uniprot id: Q5P6I2
names: Similarity
messages: Belongs to the UPF0235 family.

76114:EB RS11485
gene id: 76114:EB_RS11485
uniprot id: Q5P2K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS20015
gene id: 76114:EB_RS20015
uniprot id: Q5NXJ7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

76114:EB RS14435
gene id: 76114:EB_RS14435
uniprot id: Q5P0V2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS18825
gene id: 76114:EB_RS18825
uniprot id: Q5NY80
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS04565
gene id: 76114:EB_RS04565
uniprot id: Q5P6P1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

76114:EB RS16785
gene id: 76114:EB_RS16785
uniprot id: Q5NZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

76114:EB RS02820
gene id: 76114:EB_RS02820
uniprot id: Q5P7N6
names: Similarity
messages: Belongs to the peptidase S41A family.

76114:EB RS03035
gene id: 76114:EB_RS03035
uniprot id: Q5P7J4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

76114:EB RS18165
gene id: 76114:EB_RS18165
uniprot id: Q5NYM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS03925
gene id: 76114:EB_RS03925
uniprot id: Q5P721
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

76114:EB RS14535
gene id: 76114:EB_RS14535
uniprot id: Q5P0T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

76114:EB RS03790
gene id: 76114:EB_RS03790
uniprot id: Q5P745
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS06225
gene id: 76114:EB_RS06225
uniprot id: Q5P5P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

76114:EB RS10235
gene id: 76114:EB_RS10235
uniprot id: Q5P398
names: Similarity
messages: Belongs to the bacterial secretin family.

76114:EB RS13470
gene id: 76114:EB_RS13470
uniprot id: Q5P1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS11425
gene id: 76114:EB_RS11425
uniprot id: Q5P2L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

76114:EB RS05370
gene id: 76114:EB_RS05370
uniprot id: Q5P676
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS08000
gene id: 76114:EB_RS08000
uniprot id: Q5P4L8
names: Similarity
messages: Belongs to the UPF0145 family.

76114:EB RS06070
gene id: 76114:EB_RS06070
uniprot id: Q5P5S6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS12260
gene id: 76114:EB_RS12260
uniprot id: Q5P240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

76114:EB RS13900
gene id: 76114:EB_RS13900
uniprot id: Q5P159
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

76114:EB RS05150
gene id: 76114:EB_RS05150
uniprot id: Q5P6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

76114:EB RS07630
gene id: 76114:EB_RS07630
uniprot id: Q5P4V3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

76114:EB RS02445
gene id: 76114:EB_RS02445
uniprot id: Q5P7V5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

76114:EB RS19780
gene id: 76114:EB_RS19780
uniprot id: Q5NXP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

76114:EB RS13630
gene id: 76114:EB_RS13630
uniprot id: Q5P1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS19215
gene id: 76114:EB_RS19215
uniprot id: Q5NY01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS11635
gene id: 76114:EB_RS11635
uniprot id: Q5P2G9
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS00360
gene id: 76114:EB_RS00360
uniprot id: Q5P920
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

76114:EB RS17015
gene id: 76114:EB_RS17015
uniprot id: Q5NZB1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

76114:EB RS21650
gene id: 76114:EB_RS21650
uniprot id: Q5NWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26C family.
messages: Periplasm

76114:EB RS18175
gene id: 76114:EB_RS18175
uniprot id: Q5NYM0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

76114:EB RS12740
gene id: 76114:EB_RS12740
uniprot id: Q5P1U5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

76114:EB RS13060
gene id: 76114:EB_RS13060
uniprot id: Q5P1M7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

76114:EB RS02355
gene id: 76114:EB_RS02355
uniprot id: Q5P7X4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

76114:EB RS19740
gene id: 76114:EB_RS19740
uniprot id: Q5NXQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

76114:EB RS06360
gene id: 76114:EB_RS06360
uniprot id: Q5P5L5
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

76114:EB RS06140
gene id: 76114:EB_RS06140
uniprot id: Q5P5R0
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS01595
gene id: 76114:EB_RS01595
uniprot id: Q5P8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

76114:EB RS11065
gene id: 76114:EB_RS11065
uniprot id: Q5P2T2
names: Similarity
messages: Belongs to the NodU/CmcH family.

76114:EB RS17855
gene id: 76114:EB_RS17855
uniprot id: Q5NYT6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

76114:EB RS18290
gene id: 76114:EB_RS18290
uniprot id: Q5NYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

76114:EB RS05305
gene id: 76114:EB_RS05305
uniprot id: Q5P690
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS21485
gene id: 76114:EB_RS21485
uniprot id: Q5NWM1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

76114:EB RS01700
gene id: 76114:EB_RS01700
uniprot id: Q5P8A3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

76114:EB RS16730
gene id: 76114:EB_RS16730
uniprot id: Q5NZH5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

76114:EB RS17350
gene id: 76114:EB_RS17350
uniprot id: Q5NZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

76114:EB RS07410
gene id: 76114:EB_RS07410
uniprot id: Q5P4Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

76114:EB RS09850
gene id: 76114:EB_RS09850
uniprot id: Q5P3H5
names: Similarity
messages: Belongs to the DEAD box helicase family.

76114:EB RS00830
gene id: 76114:EB_RS00830
uniprot id: Q5P8S8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS05160
gene id: 76114:EB_RS05160
uniprot id: Q5P6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

76114:EB RS02150
gene id: 76114:EB_RS02150
uniprot id: Q5P812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

76114:EB RS02225
gene id: 76114:EB_RS02225
uniprot id: Q5P7Z7
names: Similarity
messages: Belongs to the UPF0758 family.

76114:EB RS02545
gene id: 76114:EB_RS02545
uniprot id: Q5P7U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

76114:EB RS18100
gene id: 76114:EB_RS18100
uniprot id: Q5NYN5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

76114:EB RS18685
gene id: 76114:EB_RS18685
uniprot id: Q5NYB6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

76114:EB RS17310
gene id: 76114:EB_RS17310
uniprot id: Q5NZ53
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

76114:EB RS06460
gene id: 76114:EB_RS06460
uniprot id: Q5P5J5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

76114:EB RS21475
gene id: 76114:EB_RS21475
uniprot id: Q5NWM3
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

76114:EB RS08730
gene id: 76114:EB_RS08730
uniprot id: Q5P476
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

76114:EB RS10530
gene id: 76114:EB_RS10530
uniprot id: Q5P340
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

76114:EB RS13255
gene id: 76114:EB_RS13255
uniprot id: Q5P1J1
names: Similarity
messages: Belongs to the TrpF family.

76114:EB RS18305
gene id: 76114:EB_RS18305
uniprot id: Q5NYJ3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

76114:EB RS12455
gene id: 76114:EB_RS12455
uniprot id: Q5P203
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

76114:EB RS08190
gene id: 76114:EB_RS08190
uniprot id: Q5P4I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

76114:EB RS01580
gene id: 76114:EB_RS01580
uniprot id: Q5P8C3
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

76114:EB RS12460
gene id: 76114:EB_RS12460
uniprot id: Q5P202
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

76114:EB RS03710
gene id: 76114:EB_RS03710
uniprot id: Q5P761
names: Similarity
messages: Belongs to the PhoH family.

76114:EB RS16750
gene id: 76114:EB_RS16750
uniprot id: Q5NZH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

76114:EB RS16765
gene id: 76114:EB_RS16765
uniprot id: Q5NZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

76114:EB RS08910
gene id: 76114:EB_RS08910
uniprot id: Q5P433
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

76114:EB RS00490
gene id: 76114:EB_RS00490
uniprot id: Q5P8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

76114:EB RS19000
gene id: 76114:EB_RS19000
uniprot id: Q5NY43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

76114:EB RS15655
gene id: 76114:EB_RS15655
uniprot id: Q5P045
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS21555
gene id: 76114:EB_RS21555
uniprot id: Q5NWK8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

76114:EB RS12080
gene id: 76114:EB_RS12080
uniprot id: Q5P276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

76114:EB RS03555
gene id: 76114:EB_RS03555
uniprot id: Q5P793
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

76114:EB RS05520
gene id: 76114:EB_RS05520
uniprot id: Q5P643
names: Similarity
messages: Belongs to the heat shock protein 70 family.

76114:EB RS14800
gene id: 76114:EB_RS14800
uniprot id: Q5P0M4
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS04890
gene id: 76114:EB_RS04890
uniprot id: Q5P6H7
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS08435
gene id: 76114:EB_RS08435
uniprot id: Q5P4D0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

76114:EB RS10645
gene id: 76114:EB_RS10645
uniprot id: Q5P317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

76114:EB RS08465
gene id: 76114:EB_RS08465
uniprot id: Q5P4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

76114:EB RS22145
gene id: 76114:EB_RS22145
uniprot id: Q5NW98
names: Similarity
messages: Belongs to the ParB family.

76114:EB RS12245
gene id: 76114:EB_RS12245
uniprot id: Q5P244
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS03240
gene id: 76114:EB_RS03240
uniprot id: Q5P7F5
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

76114:EB RS21225
gene id: 76114:EB_RS21225
uniprot id: Q5NWS7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

76114:EB RS08450
gene id: 76114:EB_RS08450
uniprot id: Q5P4C7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

76114:EB RS13195
gene id: 76114:EB_RS13195
uniprot id: Q5P1K3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

76114:EB RS01895
gene id: 76114:EB_RS01895
uniprot id: Q5P866
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS19735
gene id: 76114:EB_RS19735
uniprot id: Q5NXQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

76114:EB RS11600
gene id: 76114:EB_RS11600
uniprot id: Q5P2H7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

76114:EB RS16255
gene id: 76114:EB_RS16255
uniprot id: Q5NZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

76114:EB RS18285
gene id: 76114:EB_RS18285
uniprot id: Q5NYJ7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

76114:EB RS11570
gene id: 76114:EB_RS11570
uniprot id: Q5P2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS10685
gene id: 76114:EB_RS10685
uniprot id: Q5P309
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

76114:EB RS04700
gene id: 76114:EB_RS04700
uniprot id: Q5P6L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

76114:EB RS14205
gene id: 76114:EB_RS14205
uniprot id: Q5P0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

76114:EB RS22985
gene id: 76114:EB_RS22985
uniprot id: Q5NXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

76114:EB RS13660
gene id: 76114:EB_RS13660
uniprot id: Q5P1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

76114:EB RS03955
gene id: 76114:EB_RS03955
uniprot id: Q5P715
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

76114:EB RS05465
gene id: 76114:EB_RS05465
uniprot id: Q5P654
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS17625
gene id: 76114:EB_RS17625
uniprot id: Q5NYY6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

76114:EB RS02325
gene id: 76114:EB_RS02325
uniprot id: Q5P7X9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

76114:EB RS18180
gene id: 76114:EB_RS18180
uniprot id: Q5NYL9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

76114:EB RS04550
gene id: 76114:EB_RS04550
uniprot id: Q5P6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

76114:EB RS17135
gene id: 76114:EB_RS17135
uniprot id: Q5NZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

76114:EB RS14490
gene id: 76114:EB_RS14490
uniprot id: Q5P0U1
names: Similarity
messages: Belongs to the AAA ATPase family.

76114:EB RS21495
gene id: 76114:EB_RS21495
uniprot id: Q5NWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

76114:EB RS09825
gene id: 76114:EB_RS09825
uniprot id: Q5P3I1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS16825
gene id: 76114:EB_RS16825
uniprot id: Q5NZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

76114:EB RS14175
gene id: 76114:EB_RS14175
uniprot id: Q5P105
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

76114:EB RS08350
gene id: 76114:EB_RS08350
uniprot id: Q5P4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

76114:EB RS10640
gene id: 76114:EB_RS10640
uniprot id: Q5P318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

76114:EB RS16455
gene id: 76114:EB_RS16455
uniprot id: Q5NZN1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

76114:EB RS15760
gene id: 76114:EB_RS15760
uniprot id: Q5P023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

76114:EB RS06310
gene id: 76114:EB_RS06310
uniprot id: Q5P5M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

76114:EB RS13915
gene id: 76114:EB_RS13915
uniprot id: Q5P157
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS09990
gene id: 76114:EB_RS09990
uniprot id: Q5P3E7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

76114:EB RS07935
gene id: 76114:EB_RS07935
uniprot id: Q5P4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

76114:EB RS09070
gene id: 76114:EB_RS09070
uniprot id: Q5P3Z0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

76114:EB RS02795
gene id: 76114:EB_RS02795
uniprot id: Q5P7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS03855
gene id: 76114:EB_RS03855
uniprot id: Q5P732
names: Similarity
messages: Belongs to the peptidase M16 family.

76114:EB RS16275
gene id: 76114:EB_RS16275
uniprot id: Q5NZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

76114:EB RS00885
gene id: 76114:EB_RS00885
uniprot id: Q5P8R6
names: Similarity
messages: Belongs to the universal stress protein A family.

76114:EB RS12085
gene id: 76114:EB_RS12085
uniprot id: Q5P275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

76114:EB RS14225
gene id: 76114:EB_RS14225
uniprot id: Q5P0Z4
names: Similarity
messages: Belongs to the UPF0234 family.

76114:EB RS07355
gene id: 76114:EB_RS07355
uniprot id: Q5P506
names: Similarity
messages: Belongs to the band 7/mec-2 family.

76114:EB RS17880
gene id: 76114:EB_RS17880
uniprot id: Q5NYT1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

76114:EB RS04785
gene id: 76114:EB_RS04785
uniprot id: Q5P6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

76114:EB RS03050
gene id: 76114:EB_RS03050
uniprot id: Q5P7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

76114:EB RS07260
gene id: 76114:EB_RS07260
uniprot id: Q5P530
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS19540
gene id: 76114:EB_RS19540
uniprot id: Q5NXU0
names: Similarity
messages: Belongs to the P(II) protein family.

76114:EB RS11165
gene id: 76114:EB_RS11165
uniprot id: Q5P2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

76114:EB RS04645
gene id: 76114:EB_RS04645
uniprot id: Q5P6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

76114:EB RS20760
gene id: 76114:EB_RS20760
uniprot id: Q5NX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

76114:EB RS18675
gene id: 76114:EB_RS18675
uniprot id: Q5NYB8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

76114:EB RS13865
gene id: 76114:EB_RS13865
uniprot id: Q5P167
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

76114:EB RS02460
gene id: 76114:EB_RS02460
uniprot id: Q5P7V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

76114:EB RS15470
gene id: 76114:EB_RS15470
uniprot id: Q5P088
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

76114:EB RS09635
gene id: 76114:EB_RS09635
uniprot id: Q5P3M1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

76114:EB RS10055
gene id: 76114:EB_RS10055
uniprot id: Q5P3D2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS09195
gene id: 76114:EB_RS09195
uniprot id: Q5P3W6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

76114:EB RS15465
gene id: 76114:EB_RS15465
uniprot id: Q5P089
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

76114:EB RS21800
gene id: 76114:EB_RS21800
uniprot id: Q5P070
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS06095
gene id: 76114:EB_RS06095
uniprot id: Q5P5S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS11120
gene id: 76114:EB_RS11120
uniprot id: Q5P2S1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

76114:EB RS06610
gene id: 76114:EB_RS06610
uniprot id: Q5P5G9
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS13350
gene id: 76114:EB_RS13350
uniprot id: Q5P1H0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

76114:EB RS05020
gene id: 76114:EB_RS05020
uniprot id: Q5P6F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

76114:EB RS19850
gene id: 76114:EB_RS19850
uniprot id: Q5NXN0
names: Similarity
messages: Belongs to the WrbA family.

76114:EB RS17110
gene id: 76114:EB_RS17110
uniprot id: Q5NZ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

76114:EB RS04050
gene id: 76114:EB_RS04050
uniprot id: Q5P6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

76114:EB RS13290
gene id: 76114:EB_RS13290
uniprot id: Q5P1I4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS09580
gene id: 76114:EB_RS09580
uniprot id: Q5P3N2
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

76114:EB RS15825
gene id: 76114:EB_RS15825
uniprot id: Q5P010
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS17815
gene id: 76114:EB_RS17815
uniprot id: Q5NYU4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

76114:EB RS05835
gene id: 76114:EB_RS05835
uniprot id: Q5P5X8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

76114:EB RS00505
gene id: 76114:EB_RS00505
uniprot id: Q5P8Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

76114:EB RS10495
gene id: 76114:EB_RS10495
uniprot id: Q5P334
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

76114:EB RS13965
gene id: 76114:EB_RS13965
uniprot id: Q5P147
names: Function
names: Similarity
messages: Anion-transporting ATPase.
messages: Belongs to the arsA ATPase family.

76114:EB RS10905
gene id: 76114:EB_RS10905
uniprot id: Q5P2W4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS14665
gene id: 76114:EB_RS14665
uniprot id: Q5P0Q2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

76114:EB RS08230
gene id: 76114:EB_RS08230
uniprot id: Q5P4H3
names: Similarity
messages: Belongs to the DprA/Smf family.

76114:EB RS04015
gene id: 76114:EB_RS04015
uniprot id: Q5P702
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

76114:EB RS03680
gene id: 76114:EB_RS03680
uniprot id: Q5P767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

76114:EB RS07315
gene id: 76114:EB_RS07315
uniprot id: Q5P516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

76114:EB RS05935
gene id: 76114:EB_RS05935
uniprot id: Q3V7G3
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

76114:EB RS02270
gene id: 76114:EB_RS02270
uniprot id: Q5P7Y8
names: Similarity
messages: Belongs to the UPF0047 family.

76114:EB RS15890
gene id: 76114:EB_RS15890
uniprot id: Q5NZZ6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

76114:EB RS11515
gene id: 76114:EB_RS11515
uniprot id: Q5P2J5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

76114:EB RS01705
gene id: 76114:EB_RS01705
uniprot id: Q5P8A2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS04360
gene id: 76114:EB_RS04360
uniprot id: Q5P413
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS07570
gene id: 76114:EB_RS07570
uniprot id: Q5P4W6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03655
gene id: 76114:EB_RS03655
uniprot id: Q5P773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

76114:EB RS15105
gene id: 76114:EB_RS15105
uniprot id: Q5P0G0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

76114:EB RS18965
gene id: 76114:EB_RS18965
uniprot id: Q5NY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

76114:EB RS06295
gene id: 76114:EB_RS06295
uniprot id: Q5P5M9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

76114:EB RS06065
gene id: 76114:EB_RS06065
uniprot id: Q5P5S7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

76114:EB RS19785
gene id: 76114:EB_RS19785
uniprot id: Q5NXP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

76114:EB RS13920
gene id: 76114:EB_RS13920
uniprot id: Q5P156
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the PduL family.
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

76114:EB RS19910
gene id: 76114:EB_RS19910
uniprot id: Q5NXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

76114:EB RS19885
gene id: 76114:EB_RS19885
uniprot id: Q5NXM3
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS01405
gene id: 76114:EB_RS01405
uniprot id: Q5P8F7
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS10945
gene id: 76114:EB_RS10945
uniprot id: Q5P2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS16450
gene id: 76114:EB_RS16450
uniprot id: Q5NZN2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

76114:EB RS13080
gene id: 76114:EB_RS13080
uniprot id: Q5P1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

76114:EB RS17690
gene id: 76114:EB_RS17690
uniprot id: Q5NYX2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS10000
gene id: 76114:EB_RS10000
uniprot id: Q5P3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

76114:EB RS19255
gene id: 76114:EB_RS19255
uniprot id: Q5NXZ3
names: Similarity
messages: Belongs to the type IB topoisomerase family.

76114:EB RS05890
gene id: 76114:EB_RS05890
uniprot id: Q5P5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

76114:EB RS10565
gene id: 76114:EB_RS10565
uniprot id: Q5P333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

76114:EB RS13560
gene id: 76114:EB_RS13560
uniprot id: Q5P1C9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

76114:EB RS06985
gene id: 76114:EB_RS06985
uniprot id: Q5P589
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS17585
gene id: 76114:EB_RS17585
uniprot id: Q5NYZ4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS17920
gene id: 76114:EB_RS17920
uniprot id: Q5NYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS14515
gene id: 76114:EB_RS14515
uniprot id: Q5P0T6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

76114:EB RS00545
gene id: 76114:EB_RS00545
uniprot id: Q5P8Y1
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

76114:EB RS12980
gene id: 76114:EB_RS12980
uniprot id: Q5P1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

76114:EB RS03930
gene id: 76114:EB_RS03930
uniprot id: Q5P720
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

76114:EB RS19530
gene id: 76114:EB_RS19530
uniprot id: Q5NXU2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

76114:EB RS17420
gene id: 76114:EB_RS17420
uniprot id: Q5NZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS00415
gene id: 76114:EB_RS00415
uniprot id: Q5P907
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS09225
gene id: 76114:EB_RS09225
uniprot id: Q5P3V9
names: Similarity
messages: Belongs to the YoeB family.

76114:EB RS20855
gene id: 76114:EB_RS20855
uniprot id: Q5NX17
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

76114:EB RS02030
gene id: 76114:EB_RS02030
uniprot id: Q5P835
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

76114:EB RS19510
gene id: 76114:EB_RS19510
uniprot id: Q5NXU6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

76114:EB RS13740
gene id: 76114:EB_RS13740
uniprot id: Q5P193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

76114:EB RS06015
gene id: 76114:EB_RS06015
uniprot id: Q5P5T7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS22435
gene id: 76114:EB_RS22435
uniprot id: Q5NW41
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS19040
gene id: 76114:EB_RS19040
uniprot id: Q5NY35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

76114:EB RS22430
gene id: 76114:EB_RS22430
uniprot id: Q5NW42
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

76114:EB RS11775
gene id: 76114:EB_RS11775
uniprot id: Q5P2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

76114:EB RS13875
gene id: 76114:EB_RS13875
uniprot id: Q5P165
names: Similarity
messages: Belongs to the UPF0229 family.

76114:EB RS15220
gene id: 76114:EB_RS15220
uniprot id: Q5P0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

76114:EB RS09575
gene id: 76114:EB_RS09575
uniprot id: Q5P3N3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

76114:EB RS14455
gene id: 76114:EB_RS14455
uniprot id: Q5P0U8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

76114:EB RS16725
gene id: 76114:EB_RS16725
uniprot id: Q5NZH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

76114:EB RS14300
gene id: 76114:EB_RS14300
uniprot id: Q5P0X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS12485
gene id: 76114:EB_RS12485
uniprot id: Q5P1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

76114:EB RS08395
gene id: 76114:EB_RS08395
uniprot id: Q5P4D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

76114:EB RS16065
gene id: 76114:EB_RS16065
uniprot id: Q5NZW1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

76114:EB RS19720
gene id: 76114:EB_RS19720
uniprot id: Q5NXQ6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

76114:EB RS10965
gene id: 76114:EB_RS10965
uniprot id: Q5P2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS02950
gene id: 76114:EB_RS02950
uniprot id: Q5P7L1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

76114:EB RS22860
gene id: 76114:EB_RS22860
uniprot id: Q5NX67
names: Similarity
messages: Belongs to the ParB family.

76114:EB RS08340
gene id: 76114:EB_RS08340
uniprot id: Q5P4E9
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS00925
gene id: 76114:EB_RS00925
uniprot id: Q5P8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

76114:EB RS09280
gene id: 76114:EB_RS09280
uniprot id: Q5P3U6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

76114:EB RS03325
gene id: 76114:EB_RS03325
uniprot id: Q5P7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

76114:EB RS13855
gene id: 76114:EB_RS13855
uniprot id: Q5P169
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

76114:EB RS14660
gene id: 76114:EB_RS14660
uniprot id: Q5P0Q3
names: Similarity
messages: Belongs to the UPF0225 family.

76114:EB RS08495
gene id: 76114:EB_RS08495
uniprot id: Q5P4B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

76114:EB RS18690
gene id: 76114:EB_RS18690
uniprot id: Q5NYB5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

76114:EB RS05070
gene id: 76114:EB_RS05070
uniprot id: Q5P6E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

76114:EB RS07910
gene id: 76114:EB_RS07910
uniprot id: Q5P4P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

76114:EB RS10550
gene id: 76114:EB_RS10550
uniprot id: Q5P336
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

76114:EB RS18155
gene id: 76114:EB_RS18155
uniprot id: Q5NYM4
names: Similarity
messages: Belongs to the BolA/IbaG family.

76114:EB RS13715
gene id: 76114:EB_RS13715
uniprot id: Q5P198
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

76114:EB RS11880
gene id: 76114:EB_RS11880
uniprot id: Q5P2B8
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS08810
gene id: 76114:EB_RS08810
uniprot id: Q5P459
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

76114:EB RS12720
gene id: 76114:EB_RS12720
uniprot id: Q5P1U9
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

76114:EB RS13320
gene id: 76114:EB_RS13320
uniprot id: Q5P1H7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

76114:EB RS08380
gene id: 76114:EB_RS08380
uniprot id: Q5P4E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

76114:EB RS19865
gene id: 76114:EB_RS19865
uniprot id: Q5NXM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

76114:EB RS12505
gene id: 76114:EB_RS12505
uniprot id: Q5P1Z2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

76114:EB RS09470
gene id: 76114:EB_RS09470
uniprot id: Q5P3Q6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS07635
gene id: 76114:EB_RS07635
uniprot id: Q5P4V2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

76114:EB RS15980
gene id: 76114:EB_RS15980
uniprot id: Q5NZY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

76114:EB RS18700
gene id: 76114:EB_RS18700
uniprot id: Q5NYB3
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

76114:EB RS07140
gene id: 76114:EB_RS07140
uniprot id: Q5P557
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

76114:EB RS04145
gene id: 76114:EB_RS04145
uniprot id: Q5P6X6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

76114:EB RS01900
gene id: 76114:EB_RS01900
uniprot id: Q5P865
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS12450
gene id: 76114:EB_RS12450
uniprot id: Q5P206
names: Cofactor
messages: Can also use Mn(2+) ion.

76114:EB RS07715
gene id: 76114:EB_RS07715
uniprot id: Q5P4T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

76114:EB RS05025
gene id: 76114:EB_RS05025
uniprot id: Q5P6F0
names: Similarity
messages: Belongs to the UPF0502 family.

76114:EB RS04845
gene id: 76114:EB_RS04845
uniprot id: Q5P6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

76114:EB RS22015
gene id: 76114:EB_RS22015
uniprot id: Q5NWC2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS15125
gene id: 76114:EB_RS15125
uniprot id: Q5P0F6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS11605
gene id: 76114:EB_RS11605
uniprot id: Q5P2H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

76114:EB RS09005
gene id: 76114:EB_RS09005
uniprot id: Q5P413
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS13985
gene id: 76114:EB_RS13985
uniprot id: Q5P143
names: Similarity
messages: Belongs to the AOR/FOR family.

76114:EB RS16880
gene id: 76114:EB_RS16880
uniprot id: Q5NZE3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

76114:EB RS12530
gene id: 76114:EB_RS12530
uniprot id: Q5P1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

76114:EB RS07735
gene id: 76114:EB_RS07735
uniprot id: Q5P4T1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS17445
gene id: 76114:EB_RS17445
uniprot id: Q5NZ23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS02490
gene id: 76114:EB_RS02490
uniprot id: Q5P7U6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

76114:EB RS08900
gene id: 76114:EB_RS08900
uniprot id: Q5P413
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS08375
gene id: 76114:EB_RS08375
uniprot id: Q5P4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

76114:EB RS01930
gene id: 76114:EB_RS01930
uniprot id: Q5P858
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

76114:EB RS03520
gene id: 76114:EB_RS03520
uniprot id: Q5P7A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

76114:EB RS13310
gene id: 76114:EB_RS13310
uniprot id: Q5P1I0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

76114:EB RS13480
gene id: 76114:EB_RS13480
uniprot id: Q5P1E6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

76114:EB RS12135
gene id: 76114:EB_RS12135
uniprot id: Q5P265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

76114:EB RS06155
gene id: 76114:EB_RS06155
uniprot id: Q5P5Q7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

76114:EB RS07230
gene id: 76114:EB_RS07230
uniprot id: Q5P536
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS02800
gene id: 76114:EB_RS02800
uniprot id: Q5P7P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

76114:EB RS03395
gene id: 76114:EB_RS03395
uniprot id: Q5P7C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

76114:EB RS03410
gene id: 76114:EB_RS03410
uniprot id: Q5P7C1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

76114:EB RS16185
gene id: 76114:EB_RS16185
uniprot id: Q5NZT4
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS07370
gene id: 76114:EB_RS07370
uniprot id: Q5P503
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

76114:EB RS07300
gene id: 76114:EB_RS07300
uniprot id: Q5P521
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

76114:EB RS21785
gene id: 76114:EB_RS21785
uniprot id: Q5P8B0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS09565
gene id: 76114:EB_RS09565
uniprot id: Q5P3N6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

76114:EB RS10560
gene id: 76114:EB_RS10560
uniprot id: Q5P334
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

76114:EB RS13450
gene id: 76114:EB_RS13450
uniprot id: Q5P1F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

76114:EB RS11475
gene id: 76114:EB_RS11475
uniprot id: Q5P2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

76114:EB RS07640
gene id: 76114:EB_RS07640
uniprot id: Q5P4V1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

76114:EB RS17060
gene id: 76114:EB_RS17060
uniprot id: Q5NZA2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

76114:EB RS12655
gene id: 76114:EB_RS12655
uniprot id: Q5P1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

76114:EB RS17425
gene id: 76114:EB_RS17425
uniprot id: Q5NZ27
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

76114:EB RS08765
gene id: 76114:EB_RS08765
uniprot id: Q5P469
names: Similarity
messages: Belongs to the P(II) protein family.

76114:EB RS12845
gene id: 76114:EB_RS12845
uniprot id: Q5P1S1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

76114:EB RS12275
gene id: 76114:EB_RS12275
uniprot id: Q5P237
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

76114:EB RS16445
gene id: 76114:EB_RS16445
uniprot id: Q5NZN3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

76114:EB RS03945
gene id: 76114:EB_RS03945
uniprot id: Q5P717
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

76114:EB RS02730
gene id: 76114:EB_RS02730
uniprot id: Q5P7Q4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS14210
gene id: 76114:EB_RS14210
uniprot id: Q5P0Z7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

76114:EB RS12210
gene id: 76114:EB_RS12210
uniprot id: Q5P250
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

76114:EB RS15985
gene id: 76114:EB_RS15985
uniprot id: Q5NZY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

76114:EB RS13640
gene id: 76114:EB_RS13640
uniprot id: Q5P1B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS13465
gene id: 76114:EB_RS13465
uniprot id: Q5P1E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

76114:EB RS03625
gene id: 76114:EB_RS03625
uniprot id: Q5P779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS16410
gene id: 76114:EB_RS16410
uniprot id: Q5NZP0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

76114:EB RS17960
gene id: 76114:EB_RS17960
uniprot id: Q5NYR5
names: Similarity
messages: Belongs to the HisA/HisF family.

76114:EB RS08430
gene id: 76114:EB_RS08430
uniprot id: Q5P4D1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

76114:EB RS04575
gene id: 76114:EB_RS04575
uniprot id: Q5P6N9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS18550
gene id: 76114:EB_RS18550
uniprot id: Q5NYE4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

76114:EB RS02965
gene id: 76114:EB_RS02965
uniprot id: Q5P7K8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

76114:EB RS06640
gene id: 76114:EB_RS06640
uniprot id: Q5P5G3
names: Activity Regulation
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.
messages: Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
messages: Cytoplasm
messages: Divalent metal cations. Magnesium or manganese are required for activity.
messages: Inhibited by zinc ions, carbamoylphosphate and beta,gamma-imido-ATP.

76114:EB RS10050
gene id: 76114:EB_RS10050
uniprot id: Q5P3D3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS04025
gene id: 76114:EB_RS04025
uniprot id: Q5P700
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

76114:EB RS07855
gene id: 76114:EB_RS07855
uniprot id: Q5P4Q6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

76114:EB RS11400
gene id: 76114:EB_RS11400
uniprot id: Q5P2L6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

76114:EB RS06785
gene id: 76114:EB_RS06785
uniprot id: Q5P5D3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

76114:EB RS17280
gene id: 76114:EB_RS17280
uniprot id: Q5NZ59
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

76114:EB RS13120
gene id: 76114:EB_RS13120
uniprot id: Q5P1L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

76114:EB RS16105
gene id: 76114:EB_RS16105
uniprot id: Q5NZV2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS12725
gene id: 76114:EB_RS12725
uniprot id: Q5P1U8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

76114:EB RS05710
gene id: 76114:EB_RS05710
uniprot id: Q5P604
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS15060
gene id: 76114:EB_RS15060
uniprot id: Q5P0G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

76114:EB RS08575
gene id: 76114:EB_RS08575
uniprot id: Q5P4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

76114:EB RS10775
gene id: 76114:EB_RS10775
uniprot id: Q5P2Y8
names: Similarity
messages: Belongs to the pirin family.

76114:EB RS14765
gene id: 76114:EB_RS14765
uniprot id: Q5P0N1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS05235
gene id: 76114:EB_RS05235
uniprot id: Q5P6A4
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

76114:EB RS10545
gene id: 76114:EB_RS10545
uniprot id: Q5P337
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

76114:EB RS14330
gene id: 76114:EB_RS14330
uniprot id: Q5P0X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

76114:EB RS12160
gene id: 76114:EB_RS12160
uniprot id: Q5P260
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

76114:EB RS11840
gene id: 76114:EB_RS11840
uniprot id: Q5P2C7
names: Similarity
messages: Belongs to the asparagine synthetase family.

76114:EB RS22025
gene id: 76114:EB_RS22025
uniprot id: Q5NWB9
names: Similarity
messages: Belongs to the peptidase S24 family.

76114:EB RS13655
gene id: 76114:EB_RS13655
uniprot id: Q5P1A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

76114:EB RS16770
gene id: 76114:EB_RS16770
uniprot id: Q5NZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

76114:EB RS15695
gene id: 76114:EB_RS15695
uniprot id: Q5P037
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS17915
gene id: 76114:EB_RS17915
uniprot id: Q5NYS4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

76114:EB RS16230
gene id: 76114:EB_RS16230
uniprot id: Q5NZS6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

76114:EB RS17225
gene id: 76114:EB_RS17225
uniprot id: Q5NZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

76114:EB RS11740
gene id: 76114:EB_RS11740
uniprot id: Q5P2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

76114:EB RS13220
gene id: 76114:EB_RS13220
uniprot id: Q5P1J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

76114:EB RS07225
gene id: 76114:EB_RS07225
uniprot id: Q5P537
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS18170
gene id: 76114:EB_RS18170
uniprot id: Q5NYM1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS14095
gene id: 76114:EB_RS14095
uniprot id: Q5P121
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS18635
gene id: 76114:EB_RS18635
uniprot id: Q5NYC6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

76114:EB RS14190
gene id: 76114:EB_RS14190
uniprot id: Q5P102
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

76114:EB RS13885
gene id: 76114:EB_RS13885
uniprot id: Q5P162
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

76114:EB RS04095
gene id: 76114:EB_RS04095
uniprot id: Q5P6Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

76114:EB RS12885
gene id: 76114:EB_RS12885
uniprot id: Q5P1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS13475
gene id: 76114:EB_RS13475
uniprot id: Q5P1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS10520
gene id: 76114:EB_RS10520
uniprot id: Q5P342
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

76114:EB RS12285
gene id: 76114:EB_RS12285
uniprot id: Q5P235
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

76114:EB RS03515
gene id: 76114:EB_RS03515
uniprot id: Q5P7A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

76114:EB RS18595
gene id: 76114:EB_RS18595
uniprot id: Q5NYD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

76114:EB RS17230
gene id: 76114:EB_RS17230
uniprot id: Q5NZ69
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

76114:EB RS04000
gene id: 76114:EB_RS04000
uniprot id: Q5P705
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

76114:EB RS16380
gene id: 76114:EB_RS16380
uniprot id: Q5NZP6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS02595
gene id: 76114:EB_RS02595
uniprot id: Q5P7T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS16755
gene id: 76114:EB_RS16755
uniprot id: Q5NZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

76114:EB RS08245
gene id: 76114:EB_RS08245
uniprot id: Q5P4H0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

76114:EB RS11275
gene id: 76114:EB_RS11275
uniprot id: Q5P2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

76114:EB RS17080
gene id: 76114:EB_RS17080
uniprot id: Q5NZ98
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

76114:EB RS11540
gene id: 76114:EB_RS11540
uniprot id: Q5P2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

76114:EB RS11205
gene id: 76114:EB_RS11205
uniprot id: Q5P2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

76114:EB RS13265
gene id: 76114:EB_RS13265
uniprot id: Q5P1I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

76114:EB RS05585
gene id: 76114:EB_RS05585
uniprot id: Q5P630
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS02555
gene id: 76114:EB_RS02555
uniprot id: Q5P7T8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

76114:EB RS19725
gene id: 76114:EB_RS19725
uniprot id: Q5NXQ5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

76114:EB RS02890
gene id: 76114:EB_RS02890
uniprot id: Q5P7M3
names: Similarity
messages: Belongs to the ALAD family.

76114:EB RS11870
gene id: 76114:EB_RS11870
uniprot id: Q5P8B0
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS11535
gene id: 76114:EB_RS11535
uniprot id: Q5P2J1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS02550
gene id: 76114:EB_RS02550
uniprot id: Q5P7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

76114:EB RS03905
gene id: 76114:EB_RS03905
uniprot id: Q5P724
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

76114:EB RS05490
gene id: 76114:EB_RS05490
uniprot id: Q5P649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS03255
gene id: 76114:EB_RS03255
uniprot id: Q5P7F2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

76114:EB RS06630
gene id: 76114:EB_RS06630
uniprot id: Q5P5G5
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetophenone carboxylase consists of five subunits; a heterooctameric subcomplex of two alpha (Apc1), two beta (Apc2), two gamma (Apc3) and two delta (Apc4) subunits assembles with the epsilon (Apc5) subunit in an unknown stoichiometry.
messages: Belongs to the oxoprolinase family.
messages: By ethylbenzene, toluene and acetophenone.
messages: Catalyzes the carboxylation of acetophenone to form 3-oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates.
messages: Cytoplasm
messages: Divalent metal cations. Magnesium or manganese are required for activity.
messages: Inhibited by zinc ions, carbamoylphosphate and beta,gamma-imido-ATP.

76114:EB RS06835
gene id: 76114:EB_RS06835
uniprot id: Q5P5C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

76114:EB RS09650
gene id: 76114:EB_RS09650
uniprot id: Q5P3L8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

76114:EB RS19500
gene id: 76114:EB_RS19500
uniprot id: Q5NXU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

76114:EB RS17720
gene id: 76114:EB_RS17720
uniprot id: Q5NYW7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

76114:EB RS19520
gene id: 76114:EB_RS19520
uniprot id: Q5NXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

76114:EB RS07930
gene id: 76114:EB_RS07930
uniprot id: Q5P4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

76114:EB RS01585
gene id: 76114:EB_RS01585
uniprot id: Q5P8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

76114:EB RS02895
gene id: 76114:EB_RS02895
uniprot id: Q5P7M2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

76114:EB RS10010
gene id: 76114:EB_RS10010
uniprot id: Q5P3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

76114:EB RS15485
gene id: 76114:EB_RS15485
uniprot id: Q5P085
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

76114:EB RS02570
gene id: 76114:EB_RS02570
uniprot id: Q5P7T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

76114:EB RS09400
gene id: 76114:EB_RS09400
uniprot id: Q5P3S1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

76114:EB RS13460
gene id: 76114:EB_RS13460
uniprot id: Q5P1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS03220
gene id: 76114:EB_RS03220
uniprot id: Q5P7F9
names: Subcellular Location Annotation
messages: Cell outer membrane

76114:EB RS11765
gene id: 76114:EB_RS11765
uniprot id: Q5P2E3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

76114:EB RS10080
gene id: 76114:EB_RS10080
uniprot id: Q5P3C8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

76114:EB RS11770
gene id: 76114:EB_RS11770
uniprot id: Q5P2E2
names: Similarity
messages: Belongs to the SCO1/2 family.

76114:EB RS08785
gene id: 76114:EB_RS08785
uniprot id: Q5P465
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

76114:EB RS11180
gene id: 76114:EB_RS11180
uniprot id: Q5P2Q7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

76114:EB RS04040
gene id: 76114:EB_RS04040
uniprot id: Q5P6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

76114:EB RS13180
gene id: 76114:EB_RS13180
uniprot id: Q5P1K6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

76114:EB RS09415
gene id: 76114:EB_RS09415
uniprot id: Q5P3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

76114:EB RS18615
gene id: 76114:EB_RS18615
uniprot id: Q5NYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

76114:EB RS13850
gene id: 76114:EB_RS13850
uniprot id: Q5P170
names: Similarity
messages: Belongs to the threonine synthase family.

76114:EB RS11565
gene id: 76114:EB_RS11565
uniprot id: Q5P2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS06980
gene id: 76114:EB_RS06980
uniprot id: Q5P590
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

76114:EB RS10125
gene id: 76114:EB_RS10125
uniprot id: Q5P3C0
names: Similarity
messages: Belongs to the SCO1/2 family.

76114:EB RS03715
gene id: 76114:EB_RS03715
uniprot id: Q5P760
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

76114:EB RS08360
gene id: 76114:EB_RS08360
uniprot id: Q5P4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

76114:EB RS03320
gene id: 76114:EB_RS03320
uniprot id: Q5P7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

76114:EB RS02495
gene id: 76114:EB_RS02495
uniprot id: Q5P7U5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

76114:EB RS11545
gene id: 76114:EB_RS11545
uniprot id: Q5P2I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

76114:EB RS14500
gene id: 76114:EB_RS14500
uniprot id: Q5P0T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

76114:EB RS12470
gene id: 76114:EB_RS12470
uniprot id: Q5P1Z9
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS22080
gene id: 76114:EB_RS22080
uniprot id: Q5NWA8
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

76114:EB RS17805
gene id: 76114:EB_RS17805
uniprot id: Q5NYU6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

76114:EB RS06385
gene id: 76114:EB_RS06385
uniprot id: Q5P5L0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS14670
gene id: 76114:EB_RS14670
uniprot id: Q5P0Q1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

76114:EB RS02045
gene id: 76114:EB_RS02045
uniprot id: Q5P832
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

76114:EB RS12685
gene id: 76114:EB_RS12685
uniprot id: Q5P1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

76114:EB RS02770
gene id: 76114:EB_RS02770
uniprot id: Q5P7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

76114:EB RS03830
gene id: 76114:EB_RS03830
uniprot id: Q5P737
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS11015
gene id: 76114:EB_RS11015
uniprot id: Q5P2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

76114:EB RS09845
gene id: 76114:EB_RS09845
uniprot id: Q5P3H7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

76114:EB RS15950
gene id: 76114:EB_RS15950
uniprot id: Q5NZY4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS07235
gene id: 76114:EB_RS07235
uniprot id: Q5P535
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS03535
gene id: 76114:EB_RS03535
uniprot id: Q5P797
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

76114:EB RS15500
gene id: 76114:EB_RS15500
uniprot id: Q5P082
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

76114:EB RS08290
gene id: 76114:EB_RS08290
uniprot id: Q5P4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

76114:EB RS09895
gene id: 76114:EB_RS09895
uniprot id: Q5P3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

76114:EB RS17475
gene id: 76114:EB_RS17475
uniprot id: Q5NZ17
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS00425
gene id: 76114:EB_RS00425
uniprot id: Q5P905
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

76114:EB RS01230
gene id: 76114:EB_RS01230
uniprot id: Q5P8J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

76114:EB RS17825
gene id: 76114:EB_RS17825
uniprot id: Q5NYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

76114:EB RS11040
gene id: 76114:EB_RS11040
uniprot id: Q5P2T7
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

76114:EB RS14505
gene id: 76114:EB_RS14505
uniprot id: Q5P0T8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS02380
gene id: 76114:EB_RS02380
uniprot id: Q5P7W9
names: Similarity
messages: Belongs to the Ahb/Nir family.

76114:EB RS02345
gene id: 76114:EB_RS02345
uniprot id: Q5P7X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

76114:EB RS19590
gene id: 76114:EB_RS19590
uniprot id: Q5NXT1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS18295
gene id: 76114:EB_RS18295
uniprot id: Q5NYJ5
names: Similarity
messages: Belongs to the MEMO1 family.

76114:EB RS12395
gene id: 76114:EB_RS12395
uniprot id: Q5P217
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

76114:EB RS10595
gene id: 76114:EB_RS10595
uniprot id: Q5P327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

76114:EB RS15790
gene id: 76114:EB_RS15790
uniprot id: Q5P017
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS19775
gene id: 76114:EB_RS19775
uniprot id: Q5NXP6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

76114:EB RS21850
gene id: 76114:EB_RS21850
uniprot id: Q5NWF3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

76114:EB RS13840
gene id: 76114:EB_RS13840
uniprot id: Q5P172
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

76114:EB RS12475
gene id: 76114:EB_RS12475
uniprot id: Q5P1Z8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

76114:EB RS07215
gene id: 76114:EB_RS07215
uniprot id: Q5P539
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS21550
gene id: 76114:EB_RS21550
uniprot id: Q5NWK9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

76114:EB RS10665
gene id: 76114:EB_RS10665
uniprot id: Q5P313
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

76114:EB RS07335
gene id: 76114:EB_RS07335
uniprot id: Q5P512
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

76114:EB RS10590
gene id: 76114:EB_RS10590
uniprot id: Q5P328
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

76114:EB RS08510
gene id: 76114:EB_RS08510
uniprot id: Q5P4B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

76114:EB RS12200
gene id: 76114:EB_RS12200
uniprot id: Q5P252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

76114:EB RS12695
gene id: 76114:EB_RS12695
uniprot id: Q5P1V4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

76114:EB RS21780
gene id: 76114:EB_RS21780
uniprot id: Q5NWG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

76114:EB RS01240
gene id: 76114:EB_RS01240
uniprot id: Q5NY73
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

76114:EB RS16800
gene id: 76114:EB_RS16800
uniprot id: Q5NZG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

76114:EB RS03330
gene id: 76114:EB_RS03330
uniprot id: Q5P7D5
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS10290
gene id: 76114:EB_RS10290
uniprot id: Q5P387
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

76114:EB RS03935
gene id: 76114:EB_RS03935
uniprot id: Q5P719
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

76114:EB RS22335
gene id: 76114:EB_RS22335
uniprot id: Q5NW61
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

76114:EB RS19160
gene id: 76114:EB_RS19160
uniprot id: Q5NY11
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS12370
gene id: 76114:EB_RS12370
uniprot id: Q5P223
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

76114:EB RS09050
gene id: 76114:EB_RS09050
uniprot id: Q5P070
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS15245
gene id: 76114:EB_RS15245
uniprot id: Q5P0D2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

76114:EB RS19240
gene id: 76114:EB_RS19240
uniprot id: Q5NXZ6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

76114:EB RS10200
gene id: 76114:EB_RS10200
uniprot id: Q5P3A5
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS18315
gene id: 76114:EB_RS18315
uniprot id: Q5NYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

76114:EB RS14715
gene id: 76114:EB_RS14715
uniprot id: Q5P0P0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

76114:EB RS04530
gene id: 76114:EB_RS04530
uniprot id: Q5P6P7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

76114:EB RS03085
gene id: 76114:EB_RS03085
uniprot id: Q5P7I4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

76114:EB RS04135
gene id: 76114:EB_RS04135
uniprot id: Q5P6X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

76114:EB RS03440
gene id: 76114:EB_RS03440
uniprot id: Q5P7B5
names: Similarity
messages: Belongs to the YfgM family.

76114:EB RS05435
gene id: 76114:EB_RS05435
uniprot id: Q5P660
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

76114:EB RS07220
gene id: 76114:EB_RS07220
uniprot id: Q5P538
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS14165
gene id: 76114:EB_RS14165
uniprot id: Q5P107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

76114:EB RS19790
gene id: 76114:EB_RS19790
uniprot id: Q5NXP3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

76114:EB RS03910
gene id: 76114:EB_RS03910
uniprot id: Q5P723
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

76114:EB RS22275
gene id: 76114:EB_RS22275
uniprot id: Q5NW72
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS05140
gene id: 76114:EB_RS05140
uniprot id: Q5P6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

76114:EB RS17820
gene id: 76114:EB_RS17820
uniprot id: Q5NYU3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

76114:EB RS04840
gene id: 76114:EB_RS04840
uniprot id: Q5P6I7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

76114:EB RS12985
gene id: 76114:EB_RS12985
uniprot id: Q5P1P3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

76114:EB RS05335
gene id: 76114:EB_RS05335
uniprot id: Q5P684
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS01235
gene id: 76114:EB_RS01235
uniprot id: Q5P8J3
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS04885
gene id: 76114:EB_RS04885
uniprot id: Q5P6H8
names: Similarity
messages: Belongs to the GSP E family.

76114:EB RS00410
gene id: 76114:EB_RS00410
uniprot id: Q5P908
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

76114:EB RS10030
gene id: 76114:EB_RS10030
uniprot id: Q5P3D9
names: Subcellular Location Annotation
messages: Cytoplasm

76114:EB RS00130
gene id: 76114:EB_RS00130
uniprot id: Q5P973
names: Similarity
messages: Belongs to the transglycosylase Slt family.

76114:EB RS06455
gene id: 76114:EB_RS06455
uniprot id: Q5P5J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

76114:EB RS14170
gene id: 76114:EB_RS14170
uniprot id: Q5P106
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

76114:EB RS05215
gene id: 76114:EB_RS05215
uniprot id: Q5P6A8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

76114:EB RS19890
gene id: 76114:EB_RS19890
uniprot id: Q5NXM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

76114:EB RS07940
gene id: 76114:EB_RS07940
uniprot id: Q5P4N8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

76114:EB RS17330
gene id: 76114:EB_RS17330
uniprot id: Q5NZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

76114:EB RS13405
gene id: 76114:EB_RS13405
uniprot id: Q5P1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

76114:EB RS11090
gene id: 76114:EB_RS11090
uniprot id: Q5P2S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

76114:EB RS17285
gene id: 76114:EB_RS17285
uniprot id: Q5NZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

76114:EB RS16675
gene id: 76114:EB_RS16675
uniprot id: Q5NZI7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS17565
gene id: 76114:EB_RS17565
uniprot id: Q5NYZ8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

76114:EB RS11010
gene id: 76114:EB_RS11010
uniprot id: Q5P2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

76114:EB RS19895
gene id: 76114:EB_RS19895
uniprot id: Q5NXM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

76114:EB RS07275
gene id: 76114:EB_RS07275
uniprot id: Q5P527
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS17900
gene id: 76114:EB_RS17900
uniprot id: Q5NYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

76114:EB RS16735
gene id: 76114:EB_RS16735
uniprot id: Q5NZH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

76114:EB RS11510
gene id: 76114:EB_RS11510
uniprot id: Q5P2J6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

76114:EB RS15225
gene id: 76114:EB_RS15225
uniprot id: Q5P0D6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

76114:EB RS07805
gene id: 76114:EB_RS07805
uniprot id: Q5P4R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

76114:EB RS05860
gene id: 76114:EB_RS05860
uniprot id: Q5P5X3
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

76114:EB RS10695
gene id: 76114:EB_RS10695
uniprot id: Q5P307
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

76114:EB RS01450
gene id: 76114:EB_RS01450
uniprot id: Q5P8E8
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03425
gene id: 76114:EB_RS03425
uniprot id: Q5P7B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

76114:EB RS09860
gene id: 76114:EB_RS09860
uniprot id: Q5P3H3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

76114:EB RS03475
gene id: 76114:EB_RS03475
uniprot id: Q5P7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

76114:EB RS07830
gene id: 76114:EB_RS07830
uniprot id: Q5P4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

76114:EB RS12185
gene id: 76114:EB_RS12185
uniprot id: Q5P255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

76114:EB RS16265
gene id: 76114:EB_RS16265
uniprot id: Q5NZR9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

76114:EB RS08345
gene id: 76114:EB_RS08345
uniprot id: Q5P4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

76114:EB RS07865
gene id: 76114:EB_RS07865
uniprot id: Q5P4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS12540
gene id: 76114:EB_RS12540
uniprot id: Q5P1Y5
names: Similarity
messages: Belongs to the DEAD box helicase family.

76114:EB RS06270
gene id: 76114:EB_RS06270
uniprot id: Q5P5N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

76114:EB RS02320
gene id: 76114:EB_RS02320
uniprot id: Q5P7Y0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

76114:EB RS05945
gene id: 76114:EB_RS05945
uniprot id: Q5P5V0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

76114:EB RS05660
gene id: 76114:EB_RS05660
uniprot id: Q5P614
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

76114:EB RS02900
gene id: 76114:EB_RS02900
uniprot id: Q5P7M1
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

76114:EB RS13760
gene id: 76114:EB_RS13760
uniprot id: Q5P189
names: Similarity
messages: Belongs to the peptidase C40 family.

76114:EB RS03450
gene id: 76114:EB_RS03450
uniprot id: Q5P7B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

76114:EB RS02200
gene id: 76114:EB_RS02200
uniprot id: Q5P802
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

76114:EB RS15175
gene id: 76114:EB_RS15175
uniprot id: Q5P0E7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

76114:EB RS05300
gene id: 76114:EB_RS05300
uniprot id: Q5P691
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS16465
gene id: 76114:EB_RS16465
uniprot id: Q5NZM9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

76114:EB RS06485
gene id: 76114:EB_RS06485
uniprot id: Q5P5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

76114:EB RS02775
gene id: 76114:EB_RS02775
uniprot id: Q5P7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

76114:EB RS18575
gene id: 76114:EB_RS18575
uniprot id: Q5NYD9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

76114:EB RS04305
gene id: 76114:EB_RS04305
uniprot id: Q5P6U3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

76114:EB RS08110
gene id: 76114:EB_RS08110
uniprot id: Q5P4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

76114:EB RS01825
gene id: 76114:EB_RS01825
uniprot id: Q5P878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

76114:EB RS10750
gene id: 76114:EB_RS10750
uniprot id: Q5P2Z4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

76114:EB RS08115
gene id: 76114:EB_RS08115
uniprot id: Q5P4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

76114:EB RS17175
gene id: 76114:EB_RS17175
uniprot id: Q5NZ80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

76114:EB RS10195
gene id: 76114:EB_RS10195
uniprot id: Q5P3A6
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS16795
gene id: 76114:EB_RS16795
uniprot id: Q5NZG2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

76114:EB RS02735
gene id: 76114:EB_RS02735
uniprot id: Q5P7Q3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

76114:EB RS03545
gene id: 76114:EB_RS03545
uniprot id: Q5P795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

76114:EB RS16125
gene id: 76114:EB_RS16125
uniprot id: Q5NZU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

76114:EB RS00380
gene id: 76114:EB_RS00380
uniprot id: Q5P916
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

76114:EB RS05205
gene id: 76114:EB_RS05205
uniprot id: Q5P6B0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS05005
gene id: 76114:EB_RS05005
uniprot id: Q5P6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

76114:EB RS20995
gene id: 76114:EB_RS20995
uniprot id: Q5NWY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

76114:EB RS13065
gene id: 76114:EB_RS13065
uniprot id: Q5P1M6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

76114:EB RS08280
gene id: 76114:EB_RS08280
uniprot id: Q5P4G2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

76114:EB RS08460
gene id: 76114:EB_RS08460
uniprot id: Q5P4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

76114:EB RS18860
gene id: 76114:EB_RS18860
uniprot id: Q5NY71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

76114:EB RS11380
gene id: 76114:EB_RS11380
uniprot id: Q5P2M0
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

76114:EB RS11640
gene id: 76114:EB_RS11640
uniprot id: Q5P2G8
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS04060
gene id: 76114:EB_RS04060
uniprot id: Q5P6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

76114:EB RS00475
gene id: 76114:EB_RS00475
uniprot id: Q5P8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

76114:EB RS19515
gene id: 76114:EB_RS19515
uniprot id: Q5NXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

76114:EB RS13365
gene id: 76114:EB_RS13365
uniprot id: Q5P1G7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS02000
gene id: 76114:EB_RS02000
uniprot id: Q5P841
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

76114:EB RS13270
gene id: 76114:EB_RS13270
uniprot id: Q5P1I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

76114:EB RS13575
gene id: 76114:EB_RS13575
uniprot id: Q5P1C6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

76114:EB RS08525
gene id: 76114:EB_RS08525
uniprot id: Q5P4B3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

76114:EB RS00665
gene id: 76114:EB_RS00665
uniprot id: Q5P8W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

76114:EB RS11225
gene id: 76114:EB_RS11225
uniprot id: Q5P2P6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

76114:EB RS15235
gene id: 76114:EB_RS15235
uniprot id: Q5P0D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

76114:EB RS13525
gene id: 76114:EB_RS13525
uniprot id: Q5P1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS03055
gene id: 76114:EB_RS03055
uniprot id: Q5P7J0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

76114:EB RS09855
gene id: 76114:EB_RS09855
uniprot id: Q5P3H4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

76114:EB RS17925
gene id: 76114:EB_RS17925
uniprot id: Q5NYS2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

76114:EB RS10610
gene id: 76114:EB_RS10610
uniprot id: Q5P324
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

76114:EB RS11150
gene id: 76114:EB_RS11150
uniprot id: Q5P2R4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

76114:EB RS13635
gene id: 76114:EB_RS13635
uniprot id: Q5P1B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

76114:EB RS04855
gene id: 76114:EB_RS04855
uniprot id: Q5P6I4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

76114:EB RS19250
gene id: 76114:EB_RS19250
uniprot id: Q5NXZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

76114:EB RS07305
gene id: 76114:EB_RS07305
uniprot id: Q5P520
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

76114:EB RS08255
gene id: 76114:EB_RS08255
uniprot id: Q5P4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

76114:EB RS19220
gene id: 76114:EB_RS19220
uniprot id: Q5NY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

76114:EB RS02450
gene id: 76114:EB_RS02450
uniprot id: Q5P7V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

76114:EB RS09345
gene id: 76114:EB_RS09345
uniprot id: Q5P3T2
names: Similarity
messages: Belongs to the GST superfamily.

76114:EB RS08125
gene id: 76114:EB_RS08125
uniprot id: Q5P4J4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

76114:EB RS00965
gene id: 76114:EB_RS00965
uniprot id: Q5NWC2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS13730
gene id: 76114:EB_RS13730
uniprot id: Q5P195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

76114:EB RS12785
gene id: 76114:EB_RS12785
uniprot id: Q5P1T6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

76114:EB RS11455
gene id: 76114:EB_RS11455
uniprot id: Q5P2K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

76114:EB RS13505
gene id: 76114:EB_RS13505
uniprot id: Q5P1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

76114:EB RS16145
gene id: 76114:EB_RS16145
uniprot id: Q5NZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

76114:EB RS04755
gene id: 76114:EB_RS04755
uniprot id: Q5P6K4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

76114:EB RS14940
gene id: 76114:EB_RS14940
uniprot id: Q5P0J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

76114:EB RS18665
gene id: 76114:EB_RS18665
uniprot id: Q5NYC0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

76114:EB RS10770
gene id: 76114:EB_RS10770
uniprot id: Q5P2Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

76114:EB RS11145
gene id: 76114:EB_RS11145
uniprot id: Q5P2R5
names: Similarity
messages: Belongs to the CcdB toxin family.

76114:EB RS07900
gene id: 76114:EB_RS07900
uniprot id: Q5P4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

76114:EB RS10700
gene id: 76114:EB_RS10700
uniprot id: Q5P306
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

76114:EB RS11670
gene id: 76114:EB_RS11670
uniprot id: Q5P2G2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

76114:EB RS18605
gene id: 76114:EB_RS18605
uniprot id: Q5NYD3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

76114:EB RS03465
gene id: 76114:EB_RS03465
uniprot id: Q5P7B0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

76114:EB RS02745
gene id: 76114:EB_RS02745
uniprot id: Q5P7Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

76114:EB RS16035
gene id: 76114:EB_RS16035
uniprot id: Q5NZW8
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03115
gene id: 76114:EB_RS03115
uniprot id: Q5P7H9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

76114:EB RS09355
gene id: 76114:EB_RS09355
uniprot id: Q5P3T0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

76114:EB RS21480
gene id: 76114:EB_RS21480
uniprot id: Q5NWM2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS13970
gene id: 76114:EB_RS13970
uniprot id: Q5P146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

76114:EB RS21170
gene id: 76114:EB_RS21170
uniprot id: Q5NWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

76114:EB RS02750
gene id: 76114:EB_RS02750
uniprot id: Q5P7Q0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

76114:EB RS12150
gene id: 76114:EB_RS12150
uniprot id: Q5P262
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

76114:EB RS04625
gene id: 76114:EB_RS04625
uniprot id: Q5P6N2
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS03835
gene id: 76114:EB_RS03835
uniprot id: Q5P736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

76114:EB RS02680
gene id: 76114:EB_RS02680
uniprot id: Q5P7R4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

76114:EB RS22775
gene id: 76114:EB_RS22775
uniprot id: Q5NYX4
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS05080
gene id: 76114:EB_RS05080
uniprot id: Q5P6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

76114:EB RS03400
gene id: 76114:EB_RS03400
uniprot id: Q5P7C3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

76114:EB RS19840
gene id: 76114:EB_RS19840
uniprot id: Q5NXN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

76114:EB RS13040
gene id: 76114:EB_RS13040
uniprot id: Q5P1N1
names: Subcellular Location Annotation
messages: Membrane

76114:EB RS01865
gene id: 76114:EB_RS01865
uniprot id: Q5P872
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

76114:EB RS15185
gene id: 76114:EB_RS15185
uniprot id: Q5P0E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

76114:EB RS03540
gene id: 76114:EB_RS03540
uniprot id: Q5P796
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

76114:EB RS18870
gene id: 76114:EB_RS18870
uniprot id: Q5NWC2
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

76114:EB RS07390
gene id: 76114:EB_RS07390
uniprot id: Q5P4Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

76114:EB RS10615
gene id: 76114:EB_RS10615
uniprot id: Q5P323
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

76114:EB RS02740
gene id: 76114:EB_RS02740
uniprot id: Q5P7Q2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

76114:EB RS01545
gene id: 76114:EB_RS01545
uniprot id: Q5P8C9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.