758847:LSS RS15140
gene id: 758847:LSS_RS15140
uniprot id: K8Y5F5
names: Similarity
messages: Belongs to the pirin family.

758847:LSS RS11000
gene id: 758847:LSS_RS11000
uniprot id: K8Y5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

758847:LSS RS04940
gene id: 758847:LSS_RS04940
uniprot id: K8YE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

758847:LSS RS05185
gene id: 758847:LSS_RS05185
uniprot id: K8YH06
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

758847:LSS RS15340
gene id: 758847:LSS_RS15340
uniprot id: K8YEF8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

758847:LSS RS03775
gene id: 758847:LSS_RS03775
uniprot id: K8XY61
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14095
gene id: 758847:LSS_RS14095
uniprot id: K8Y613
names: Subcellular Location Annotation
messages: Periplasmic flagellum

758847:LSS RS12475
gene id: 758847:LSS_RS12475
uniprot id: K8XX43
names: Similarity
messages: Belongs to the CapA family.

758847:LSS RS02465
gene id: 758847:LSS_RS02465
uniprot id: K8XVL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

758847:LSS RS02655
gene id: 758847:LSS_RS02655
uniprot id: K8YFA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

758847:LSS RS13965
gene id: 758847:LSS_RS13965
uniprot id: K8Y3Y2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

758847:LSS RS11220
gene id: 758847:LSS_RS11220
uniprot id: A0A097ESR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

758847:LSS RS15860
gene id: 758847:LSS_RS15860
uniprot id: K8XUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

758847:LSS RS05785
gene id: 758847:LSS_RS05785
uniprot id: K8Y477
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758847:LSS RS16040
gene id: 758847:LSS_RS16040
uniprot id: K8Y1C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

758847:LSS RS11165
gene id: 758847:LSS_RS11165
uniprot id: K8Y4D6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

758847:LSS RS05685
gene id: 758847:LSS_RS05685
uniprot id: K8YGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

758847:LSS RS10985
gene id: 758847:LSS_RS10985
uniprot id: K8Y3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

758847:LSS RS06240
gene id: 758847:LSS_RS06240
uniprot id: K8XYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

758847:LSS RS16935
gene id: 758847:LSS_RS16935
uniprot id: K8XUK5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

758847:LSS RS16500
gene id: 758847:LSS_RS16500
uniprot id: K8YDX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

758847:LSS RS13945
gene id: 758847:LSS_RS13945
uniprot id: K8XUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

758847:LSS RS01940
gene id: 758847:LSS_RS01940
uniprot id: K8XU99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

758847:LSS RS08080
gene id: 758847:LSS_RS08080
uniprot id: K8Y9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

758847:LSS RS10445
gene id: 758847:LSS_RS10445
uniprot id: K8XVT0
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS02370
gene id: 758847:LSS_RS02370
uniprot id: K8XX20
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

758847:LSS RS06505
gene id: 758847:LSS_RS06505
uniprot id: K8XZ39
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS04960
gene id: 758847:LSS_RS04960
uniprot id: K8Y4S5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

758847:LSS RS15235
gene id: 758847:LSS_RS15235
uniprot id: K8Y6T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

758847:LSS RS15390
gene id: 758847:LSS_RS15390
uniprot id: K8YEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

758847:LSS RS02100
gene id: 758847:LSS_RS02100
uniprot id: K8Y990
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

758847:LSS RS14865
gene id: 758847:LSS_RS14865
uniprot id: K8Y5B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

758847:LSS RS09230
gene id: 758847:LSS_RS09230
uniprot id: K8XT70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

758847:LSS RS18720
gene id: 758847:LSS_RS18720
uniprot id: K8YC82
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

758847:LSS RS16350
gene id: 758847:LSS_RS16350
uniprot id: K8Y273
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

758847:LSS RS04235
gene id: 758847:LSS_RS04235
uniprot id: K8YBK2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

758847:LSS RS10620
gene id: 758847:LSS_RS10620
uniprot id: K8XUM3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

758847:LSS RS01445
gene id: 758847:LSS_RS01445
uniprot id: K8Y1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

758847:LSS RS15685
gene id: 758847:LSS_RS15685
uniprot id: K8YAE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

758847:LSS RS14390
gene id: 758847:LSS_RS14390
uniprot id: K8YEJ4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS15265
gene id: 758847:LSS_RS15265
uniprot id: K8Y6T7
names: Subcellular Location Annotation
messages: Periplasmic flagellum

758847:LSS RS08450
gene id: 758847:LSS_RS08450
uniprot id: K8XVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

758847:LSS RS09725
gene id: 758847:LSS_RS09725
uniprot id: K8Y017
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodecamer; pentamer of dimers.

758847:LSS RS05460
gene id: 758847:LSS_RS05460
uniprot id: K8Y6B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

758847:LSS RS05085
gene id: 758847:LSS_RS05085
uniprot id: K8Y4Q5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS17830
gene id: 758847:LSS_RS17830
uniprot id: K8YAE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758847:LSS RS09330
gene id: 758847:LSS_RS09330
uniprot id: K8XUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

758847:LSS RS15610
gene id: 758847:LSS_RS15610
uniprot id: K8XZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

758847:LSS RS11275
gene id: 758847:LSS_RS11275
uniprot id: K8YD82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

758847:LSS RS20130
gene id: 758847:LSS_RS20130
uniprot id: K8Y5X4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

758847:LSS RS16280
gene id: 758847:LSS_RS16280
uniprot id: K8YAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

758847:LSS RS02420
gene id: 758847:LSS_RS02420
uniprot id: K8XVP9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758847:LSS RS06880
gene id: 758847:LSS_RS06880
uniprot id: K8XZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

758847:LSS RS13560
gene id: 758847:LSS_RS13560
uniprot id: K8YAP8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

758847:LSS RS13260
gene id: 758847:LSS_RS13260
uniprot id: K8Y1U3
names: Similarity
messages: Belongs to the ribF family.

758847:LSS RS13020
gene id: 758847:LSS_RS13020
uniprot id: K8XWP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

758847:LSS RS15600
gene id: 758847:LSS_RS15600
uniprot id: K8Y0V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

758847:LSS RS11270
gene id: 758847:LSS_RS11270
uniprot id: K8Y5R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

758847:LSS RS17945
gene id: 758847:LSS_RS17945
uniprot id: K8Y1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

758847:LSS RS14960
gene id: 758847:LSS_RS14960
uniprot id: K8YEX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

758847:LSS RS10470
gene id: 758847:LSS_RS10470
uniprot id: K8XVS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

758847:LSS RS14700
gene id: 758847:LSS_RS14700
uniprot id: K8Y577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

758847:LSS RS08070
gene id: 758847:LSS_RS08070
uniprot id: K8XYD7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

758847:LSS RS05060
gene id: 758847:LSS_RS05060
uniprot id: K8Y5B5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758847:LSS RS00580
gene id: 758847:LSS_RS00580
uniprot id: K8Y4E1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS06355
gene id: 758847:LSS_RS06355
uniprot id: K8Y0G0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

758847:LSS RS05215
gene id: 758847:LSS_RS05215
uniprot id: K8Y587
names: Similarity
messages: Belongs to the YciI family.

758847:LSS RS15815
gene id: 758847:LSS_RS15815
uniprot id: K8Y7R9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

758847:LSS RS17260
gene id: 758847:LSS_RS17260
uniprot id: K8Y2B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS05125
gene id: 758847:LSS_RS05125
uniprot id: K8Y5A3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS13760
gene id: 758847:LSS_RS13760
uniprot id: K8Y1V3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

758847:LSS RS11360
gene id: 758847:LSS_RS11360
uniprot id: K8Y4H9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

758847:LSS RS06540
gene id: 758847:LSS_RS06540
uniprot id: K8Y0K8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

758847:LSS RS12395
gene id: 758847:LSS_RS12395
uniprot id: K8XVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

758847:LSS RS11915
gene id: 758847:LSS_RS11915
uniprot id: K8XXC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

758847:LSS RS16895
gene id: 758847:LSS_RS16895
uniprot id: K8Y5N4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

758847:LSS RS12365
gene id: 758847:LSS_RS12365
uniprot id: K8XW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758847:LSS RS03140
gene id: 758847:LSS_RS03140
uniprot id: K8YCM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS02260
gene id: 758847:LSS_RS02260
uniprot id: K8Y6P3
names: Similarity
messages: Belongs to the acylphosphatase family.

758847:LSS RS16515
gene id: 758847:LSS_RS16515
uniprot id: K8YB40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS09150
gene id: 758847:LSS_RS09150
uniprot id: K8XZF0
names: Similarity
messages: Belongs to the peptidase U62 family.

758847:LSS RS16235
gene id: 758847:LSS_RS16235
uniprot id: K8YAZ8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS15430
gene id: 758847:LSS_RS15430
uniprot id: K8Y7S5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758847:LSS RS00370
gene id: 758847:LSS_RS00370
uniprot id: K8XYZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS12300
gene id: 758847:LSS_RS12300
uniprot id: K8Y4E3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS14195
gene id: 758847:LSS_RS14195
uniprot id: K8XWY7
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

758847:LSS RS16450
gene id: 758847:LSS_RS16450
uniprot id: K8Y3X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

758847:LSS RS18505
gene id: 758847:LSS_RS18505
uniprot id: K8Y2H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

758847:LSS RS02555
gene id: 758847:LSS_RS02555
uniprot id: K8Y352
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

758847:LSS RS13970
gene id: 758847:LSS_RS13970
uniprot id: K8XUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

758847:LSS RS14025
gene id: 758847:LSS_RS14025
uniprot id: K8Y629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

758847:LSS RS10380
gene id: 758847:LSS_RS10380
uniprot id: K8Y4Q4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

758847:LSS RS16170
gene id: 758847:LSS_RS16170
uniprot id: K8Y8A3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

758847:LSS RS10235
gene id: 758847:LSS_RS10235
uniprot id: K8Y743
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

758847:LSS RS09025
gene id: 758847:LSS_RS09025
uniprot id: K8Y6G3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS06455
gene id: 758847:LSS_RS06455
uniprot id: K8YAB4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

758847:LSS RS18550
gene id: 758847:LSS_RS18550
uniprot id: K8Y9L5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

758847:LSS RS08585
gene id: 758847:LSS_RS08585
uniprot id: K8XY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758847:LSS RS00330
gene id: 758847:LSS_RS00330
uniprot id: K8XX34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758847:LSS RS07350
gene id: 758847:LSS_RS07350
uniprot id: K8Y0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

758847:LSS RS01630
gene id: 758847:LSS_RS01630
uniprot id: K8Y9U9
names: Similarity
messages: Belongs to the ycf81 family.

758847:LSS RS11080
gene id: 758847:LSS_RS11080
uniprot id: K8Y3T1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

758847:LSS RS11170
gene id: 758847:LSS_RS11170
uniprot id: K8YG03
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758847:LSS RS08920
gene id: 758847:LSS_RS08920
uniprot id: K8XY25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

758847:LSS RS12340
gene id: 758847:LSS_RS12340
uniprot id: K8XW08
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS14360
gene id: 758847:LSS_RS14360
uniprot id: K8Y6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

758847:LSS RS10015
gene id: 758847:LSS_RS10015
uniprot id: K8Y092
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

758847:LSS RS03540
gene id: 758847:LSS_RS03540
uniprot id: K8XUY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS18470
gene id: 758847:LSS_RS18470
uniprot id: K8Y0P3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

758847:LSS RS03820
gene id: 758847:LSS_RS03820
uniprot id: K8YB87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

758847:LSS RS10900
gene id: 758847:LSS_RS10900
uniprot id: K8Y5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

758847:LSS RS06085
gene id: 758847:LSS_RS06085
uniprot id: K8Y3R4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

758847:LSS RS18130
gene id: 758847:LSS_RS18130
uniprot id: K8Y1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS08130
gene id: 758847:LSS_RS08130
uniprot id: K8YA06
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS13040
gene id: 758847:LSS_RS13040
uniprot id: K8XW74
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS02445
gene id: 758847:LSS_RS02445
uniprot id: A0A097ES14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

758847:LSS RS07445
gene id: 758847:LSS_RS07445
uniprot id: K8Y942
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

758847:LSS RS10765
gene id: 758847:LSS_RS10765
uniprot id: K8Y5G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS03210
gene id: 758847:LSS_RS03210
uniprot id: K8Y3G3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS06950
gene id: 758847:LSS_RS06950
uniprot id: K8YAT6
names: Similarity
messages: Belongs to the sigma-54 factor family.

758847:LSS RS02590
gene id: 758847:LSS_RS02590
uniprot id: K8YCB9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

758847:LSS RS06090
gene id: 758847:LSS_RS06090
uniprot id: K8XWR4
names: Subcellular Location Annotation
messages: Periplasm

758847:LSS RS17885
gene id: 758847:LSS_RS17885
uniprot id: K8Y347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

758847:LSS RS04615
gene id: 758847:LSS_RS04615
uniprot id: K8Y626
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

758847:LSS RS03185
gene id: 758847:LSS_RS03185
uniprot id: K8Y5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

758847:LSS RS14850
gene id: 758847:LSS_RS14850
uniprot id: K8YHS9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

758847:LSS RS13425
gene id: 758847:LSS_RS13425
uniprot id: K8Y250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

758847:LSS RS03135
gene id: 758847:LSS_RS03135
uniprot id: K8Y5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS16740
gene id: 758847:LSS_RS16740
uniprot id: K8YDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

758847:LSS RS00660
gene id: 758847:LSS_RS00660
uniprot id: K8YEM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758847:LSS RS06050
gene id: 758847:LSS_RS06050
uniprot id: K8XVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

758847:LSS RS11305
gene id: 758847:LSS_RS11305
uniprot id: K8Y3Y4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

758847:LSS RS01195
gene id: 758847:LSS_RS01195
uniprot id: K8Y3H8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758847:LSS RS03275
gene id: 758847:LSS_RS03275
uniprot id: K8Y5C7
names: Similarity
messages: Belongs to the peptidase M16 family.

758847:LSS RS14910
gene id: 758847:LSS_RS14910
uniprot id: K8YEW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

758847:LSS RS07175
gene id: 758847:LSS_RS07175
uniprot id: K8XVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

758847:LSS RS03620
gene id: 758847:LSS_RS03620
uniprot id: K8XYA0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

758847:LSS RS13790
gene id: 758847:LSS_RS13790
uniprot id: K8Y2X2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

758847:LSS RS07890
gene id: 758847:LSS_RS07890
uniprot id: K8XTH3
names: Similarity
messages: Belongs to the catalase family.

758847:LSS RS01575
gene id: 758847:LSS_RS01575
uniprot id: K8Y1B0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

758847:LSS RS07430
gene id: 758847:LSS_RS07430
uniprot id: K8Y0K1
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS12210
gene id: 758847:LSS_RS12210
uniprot id: K8XWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS07620
gene id: 758847:LSS_RS07620
uniprot id: K8Y975
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

758847:LSS RS13465
gene id: 758847:LSS_RS13465
uniprot id: K8Y241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

758847:LSS RS00540
gene id: 758847:LSS_RS00540
uniprot id: K8XVD8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS15555
gene id: 758847:LSS_RS15555
uniprot id: K8Y7V7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

758847:LSS RS08970
gene id: 758847:LSS_RS08970
uniprot id: K8XY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

758847:LSS RS04580
gene id: 758847:LSS_RS04580
uniprot id: K8Y8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

758847:LSS RS04970
gene id: 758847:LSS_RS04970
uniprot id: K8Y6M6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS00510
gene id: 758847:LSS_RS00510
uniprot id: K8Y3T9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

758847:LSS RS14060
gene id: 758847:LSS_RS14060
uniprot id: K8Y3G5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

758847:LSS RS04160
gene id: 758847:LSS_RS04160
uniprot id: K8Y2U8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

758847:LSS RS05650
gene id: 758847:LSS_RS05650
uniprot id: K8Y4B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

758847:LSS RS13325
gene id: 758847:LSS_RS13325
uniprot id: K8Y1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

758847:LSS RS02600
gene id: 758847:LSS_RS02600
uniprot id: K8YF92
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

758847:LSS RS12280
gene id: 758847:LSS_RS12280
uniprot id: K8Y711
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

758847:LSS RS00145
gene id: 758847:LSS_RS00145
uniprot id: K8Y7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

758847:LSS RS00635
gene id: 758847:LSS_RS00635
uniprot id: K8Y4F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758847:LSS RS03345
gene id: 758847:LSS_RS03345
uniprot id: K8Y3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758847:LSS RS17500
gene id: 758847:LSS_RS17500
uniprot id: K8XU95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

758847:LSS RS05815
gene id: 758847:LSS_RS05815
uniprot id: K8XUT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

758847:LSS RS15355
gene id: 758847:LSS_RS15355
uniprot id: K8Y5J6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS06890
gene id: 758847:LSS_RS06890
uniprot id: K8Y820
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

758847:LSS RS17055
gene id: 758847:LSS_RS17055
uniprot id: K8XUH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

758847:LSS RS18195
gene id: 758847:LSS_RS18195
uniprot id: K8Y2X7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

758847:LSS RS14460
gene id: 758847:LSS_RS14460
uniprot id: K8Y6Z2
names: Similarity
messages: Belongs to the Dps family.

758847:LSS RS13595
gene id: 758847:LSS_RS13595
uniprot id: K8YDG7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758847:LSS RS16815
gene id: 758847:LSS_RS16815
uniprot id: K8Y1W6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS18060
gene id: 758847:LSS_RS18060
uniprot id: K8Y1K2
names: Similarity
messages: Belongs to the peptidase S16 family.

758847:LSS RS09800
gene id: 758847:LSS_RS09800
uniprot id: K8Y8L6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14860
gene id: 758847:LSS_RS14860
uniprot id: K8YEV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

758847:LSS RS07645
gene id: 758847:LSS_RS07645
uniprot id: K8Y980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

758847:LSS RS01835
gene id: 758847:LSS_RS01835
uniprot id: K8Y154
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS16920
gene id: 758847:LSS_RS16920
uniprot id: K8XW24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

758847:LSS RS17435
gene id: 758847:LSS_RS17435
uniprot id: K8YC25
names: Similarity
messages: Belongs to the heat shock protein 90 family.

758847:LSS RS07875
gene id: 758847:LSS_RS07875
uniprot id: K8XVM3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

758847:LSS RS08215
gene id: 758847:LSS_RS08215
uniprot id: K8Y0B2
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS03315
gene id: 758847:LSS_RS03315
uniprot id: K8Y5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

758847:LSS RS02140
gene id: 758847:LSS_RS02140
uniprot id: K8XXQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS16275
gene id: 758847:LSS_RS16275
uniprot id: K8Y170
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

758847:LSS RS15630
gene id: 758847:LSS_RS15630
uniprot id: K8Y7N6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

758847:LSS RS09175
gene id: 758847:LSS_RS09175
uniprot id: K8Y900
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

758847:LSS RS09845
gene id: 758847:LSS_RS09845
uniprot id: K8Y8N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

758847:LSS RS07510
gene id: 758847:LSS_RS07510
uniprot id: K8YBX6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

758847:LSS RS08090
gene id: 758847:LSS_RS08090
uniprot id: K8Y787
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

758847:LSS RS10965
gene id: 758847:LSS_RS10965
uniprot id: K8Y493
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

758847:LSS RS05265
gene id: 758847:LSS_RS05265
uniprot id: K8YE15
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS05820
gene id: 758847:LSS_RS05820
uniprot id: K8Y5V6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS07490
gene id: 758847:LSS_RS07490
uniprot id: K8Y215
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS06895
gene id: 758847:LSS_RS06895
uniprot id: K8XZ67
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

758847:LSS RS11670
gene id: 758847:LSS_RS11670
uniprot id: K8Y4R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

758847:LSS RS04870
gene id: 758847:LSS_RS04870
uniprot id: K8YE97
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS15865
gene id: 758847:LSS_RS15865
uniprot id: K8Y2V8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

758847:LSS RS11295
gene id: 758847:LSS_RS11295
uniprot id: K8Y5S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758847:LSS RS04015
gene id: 758847:LSS_RS04015
uniprot id: K8Y2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758847:LSS RS17940
gene id: 758847:LSS_RS17940
uniprot id: K8YD54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

758847:LSS RS02400
gene id: 758847:LSS_RS02400
uniprot id: K8Y6N4
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

758847:LSS RS11210
gene id: 758847:LSS_RS11210
uniprot id: K8Y4E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

758847:LSS RS10140
gene id: 758847:LSS_RS10140
uniprot id: K8Y8Y4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

758847:LSS RS07045
gene id: 758847:LSS_RS07045
uniprot id: K8XZP4
names: Similarity
messages: Belongs to the UPF0102 family.

758847:LSS RS05715
gene id: 758847:LSS_RS05715
uniprot id: K8Y4V2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

758847:LSS RS09325
gene id: 758847:LSS_RS09325
uniprot id: K8Y5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

758847:LSS RS01960
gene id: 758847:LSS_RS01960
uniprot id: K8Y2U9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS11845
gene id: 758847:LSS_RS11845
uniprot id: K8XXD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

758847:LSS RS11840
gene id: 758847:LSS_RS11840
uniprot id: K8XXV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

758847:LSS RS16805
gene id: 758847:LSS_RS16805
uniprot id: K8YDQ6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS13035
gene id: 758847:LSS_RS13035
uniprot id: K8Y519
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

758847:LSS RS05695
gene id: 758847:LSS_RS05695
uniprot id: K8Y499
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

758847:LSS RS15850
gene id: 758847:LSS_RS15850
uniprot id: K8XVU6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS05575
gene id: 758847:LSS_RS05575
uniprot id: K8Y4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

758847:LSS RS13925
gene id: 758847:LSS_RS13925
uniprot id: K8XVG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

758847:LSS RS15840
gene id: 758847:LSS_RS15840
uniprot id: K8Y7S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

758847:LSS RS14010
gene id: 758847:LSS_RS14010
uniprot id: K8XUG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

758847:LSS RS08770
gene id: 758847:LSS_RS08770
uniprot id: K8Y9I4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

758847:LSS RS13225
gene id: 758847:LSS_RS13225
uniprot id: K8Y3N3
names: Similarity
messages: Belongs to the UPF0473 family.

758847:LSS RS16355
gene id: 758847:LSS_RS16355
uniprot id: K8YB74
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS14030
gene id: 758847:LSS_RS14030
uniprot id: K8XV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

758847:LSS RS04570
gene id: 758847:LSS_RS04570
uniprot id: K8XX58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

758847:LSS RS05425
gene id: 758847:LSS_RS05425
uniprot id: K8YDX9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

758847:LSS RS13615
gene id: 758847:LSS_RS13615
uniprot id: K8Y208
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS18055
gene id: 758847:LSS_RS18055
uniprot id: K8YD15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

758847:LSS RS17965
gene id: 758847:LSS_RS17965
uniprot id: K8Y1B9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

758847:LSS RS11695
gene id: 758847:LSS_RS11695
uniprot id: K8Y4S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS00495
gene id: 758847:LSS_RS00495
uniprot id: K8XUU1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

758847:LSS RS17230
gene id: 758847:LSS_RS17230
uniprot id: K8Y9F3
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

758847:LSS RS11955
gene id: 758847:LSS_RS11955
uniprot id: K8XXB2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

758847:LSS RS15045
gene id: 758847:LSS_RS15045
uniprot id: K8Y615
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

758847:LSS RS14155
gene id: 758847:LSS_RS14155
uniprot id: K8Y5I3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

758847:LSS RS10265
gene id: 758847:LSS_RS10265
uniprot id: K8XW42
names: Similarity
messages: Belongs to the CinA family.

758847:LSS RS14885
gene id: 758847:LSS_RS14885
uniprot id: K8YEV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

758847:LSS RS14940
gene id: 758847:LSS_RS14940
uniprot id: K8Y5C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

758847:LSS RS04945
gene id: 758847:LSS_RS04945
uniprot id: K8Y6N0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS16085
gene id: 758847:LSS_RS16085
uniprot id: K8YB43
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS02645
gene id: 758847:LSS_RS02645
uniprot id: K8YCD4
names: Similarity
messages: Belongs to the SufE family.

758847:LSS RS10385
gene id: 758847:LSS_RS10385
uniprot id: K8XXQ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

758847:LSS RS06705
gene id: 758847:LSS_RS06705
uniprot id: K8XZ26
names: Similarity
messages: Belongs to the MreC family.

758847:LSS RS13745
gene id: 758847:LSS_RS13745
uniprot id: K8YAJ5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

758847:LSS RS06100
gene id: 758847:LSS_RS06100
uniprot id: K8XV99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

758847:LSS RS10625
gene id: 758847:LSS_RS10625
uniprot id: K8XU06
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

758847:LSS RS12370
gene id: 758847:LSS_RS12370
uniprot id: K8XVG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS08360
gene id: 758847:LSS_RS08360
uniprot id: K8XXL9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

758847:LSS RS12000
gene id: 758847:LSS_RS12000
uniprot id: K8Y664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS07080
gene id: 758847:LSS_RS07080
uniprot id: K8Y155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

758847:LSS RS13695
gene id: 758847:LSS_RS13695
uniprot id: K8Y3C8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS02345
gene id: 758847:LSS_RS02345
uniprot id: K8Y6L4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

758847:LSS RS09635
gene id: 758847:LSS_RS09635
uniprot id: K8XYQ7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

758847:LSS RS03530
gene id: 758847:LSS_RS03530
uniprot id: K8Y3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

758847:LSS RS17690
gene id: 758847:LSS_RS17690
uniprot id: K8Y4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758847:LSS RS07580
gene id: 758847:LSS_RS07580
uniprot id: K8Y090
names: Similarity
messages: Belongs to the FGGY kinase family.

758847:LSS RS04020
gene id: 758847:LSS_RS04020
uniprot id: K8YE86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758847:LSS RS01100
gene id: 758847:LSS_RS01100
uniprot id: K8Y2X9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS02385
gene id: 758847:LSS_RS02385
uniprot id: K8XVN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

758847:LSS RS13995
gene id: 758847:LSS_RS13995
uniprot id: K8Y3I1
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS08415
gene id: 758847:LSS_RS08415
uniprot id: K8XXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

758847:LSS RS10465
gene id: 758847:LSS_RS10465
uniprot id: K8XWB0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

758847:LSS RS13250
gene id: 758847:LSS_RS13250
uniprot id: K8YAW0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS18220
gene id: 758847:LSS_RS18220
uniprot id: K8Y2X3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

758847:LSS RS08930
gene id: 758847:LSS_RS08930
uniprot id: K8Y9N2
names: Similarity
messages: Belongs to the peptidase S49 family.

758847:LSS RS14375
gene id: 758847:LSS_RS14375
uniprot id: K8Y5M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS10750
gene id: 758847:LSS_RS10750
uniprot id: K8Y3L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

758847:LSS RS00240
gene id: 758847:LSS_RS00240
uniprot id: K8Y8K1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS07640
gene id: 758847:LSS_RS07640
uniprot id: K8Y246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758847:LSS RS03920
gene id: 758847:LSS_RS03920
uniprot id: K8Y2P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS17515
gene id: 758847:LSS_RS17515
uniprot id: K8Y5X3
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS03450
gene id: 758847:LSS_RS03450
uniprot id: K8Y2J8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14005
gene id: 758847:LSS_RS14005
uniprot id: K8XV16
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

758847:LSS RS10290
gene id: 758847:LSS_RS10290
uniprot id: K8XW38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

758847:LSS RS14640
gene id: 758847:LSS_RS14640
uniprot id: K8Y561
names: Similarity
messages: Belongs to the citrate synthase family.

758847:LSS RS06360
gene id: 758847:LSS_RS06360
uniprot id: K8Y7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

758847:LSS RS02425
gene id: 758847:LSS_RS02425
uniprot id: K8XX37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

758847:LSS RS05140
gene id: 758847:LSS_RS05140
uniprot id: K8Y6J6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14015
gene id: 758847:LSS_RS14015
uniprot id: K8Y3H5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

758847:LSS RS07945
gene id: 758847:LSS_RS07945
uniprot id: K8XYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

758847:LSS RS15350
gene id: 758847:LSS_RS15350
uniprot id: K8Y4Y5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

758847:LSS RS16930
gene id: 758847:LSS_RS16930
uniprot id: K8XTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

758847:LSS RS13610
gene id: 758847:LSS_RS13610
uniprot id: K8YDG5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

758847:LSS RS01280
gene id: 758847:LSS_RS01280
uniprot id: K8YF74
names: Similarity
messages: Belongs to the CutA family.

758847:LSS RS17155
gene id: 758847:LSS_RS17155
uniprot id: K8XWI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

758847:LSS RS05710
gene id: 758847:LSS_RS05710
uniprot id: K8YGI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

758847:LSS RS00985
gene id: 758847:LSS_RS00985
uniprot id: K8Y2V2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS18680
gene id: 758847:LSS_RS18680
uniprot id: K8Y0J3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

758847:LSS RS16660
gene id: 758847:LSS_RS16660
uniprot id: K8YB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

758847:LSS RS03175
gene id: 758847:LSS_RS03175
uniprot id: K8Y3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS14945
gene id: 758847:LSS_RS14945
uniprot id: K8Y5Y9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

758847:LSS RS03855
gene id: 758847:LSS_RS03855
uniprot id: K8Y2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

758847:LSS RS17760
gene id: 758847:LSS_RS17760
uniprot id: K8Y382
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

758847:LSS RS06900
gene id: 758847:LSS_RS06900
uniprot id: K8XZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

758847:LSS RS05740
gene id: 758847:LSS_RS05740
uniprot id: K8Y4U4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

758847:LSS RS18230
gene id: 758847:LSS_RS18230
uniprot id: K8Y1H1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

758847:LSS RS00135
gene id: 758847:LSS_RS00135
uniprot id: K8Y5A2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

758847:LSS RS01365
gene id: 758847:LSS_RS01365
uniprot id: K8YCT7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

758847:LSS RS17780
gene id: 758847:LSS_RS17780
uniprot id: K8YAG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS00065
gene id: 758847:LSS_RS00065
uniprot id: K8Y5C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

758847:LSS RS14055
gene id: 758847:LSS_RS14055
uniprot id: K8XUE8
names: Similarity
messages: Belongs to the peptidase S33 family.

758847:LSS RS06110
gene id: 758847:LSS_RS06110
uniprot id: K8Y3Q8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS06510
gene id: 758847:LSS_RS06510
uniprot id: K8YAC5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

758847:LSS RS10390
gene id: 758847:LSS_RS10390
uniprot id: K8Y7B8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

758847:LSS RS14805
gene id: 758847:LSS_RS14805
uniprot id: K8YHR9
names: Similarity
messages: Belongs to the AHA1 family.

758847:LSS RS06980
gene id: 758847:LSS_RS06980
uniprot id: K8Y133
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS07465
gene id: 758847:LSS_RS07465
uniprot id: K8Y210
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758847:LSS RS12135
gene id: 758847:LSS_RS12135
uniprot id: K8Y4U1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

758847:LSS RS14530
gene id: 758847:LSS_RS14530
uniprot id: K8Y5Q6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

758847:LSS RS11180
gene id: 758847:LSS_RS11180
uniprot id: K8YD59
names: Similarity
messages: Belongs to the UPF0758 family.

758847:LSS RS08345
gene id: 758847:LSS_RS08345
uniprot id: K8XW92
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

758847:LSS RS11060
gene id: 758847:LSS_RS11060
uniprot id: K8Y4B0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

758847:LSS RS10180
gene id: 758847:LSS_RS10180
uniprot id: K8XXI5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

758847:LSS RS05725
gene id: 758847:LSS_RS05725
uniprot id: K8YDL6
names: Similarity
messages: Belongs to the peptidase S41A family.

758847:LSS RS08740
gene id: 758847:LSS_RS08740
uniprot id: K8XYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

758847:LSS RS14890
gene id: 758847:LSS_RS14890
uniprot id: K8Y5B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS13955
gene id: 758847:LSS_RS13955
uniprot id: K8Y6H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

758847:LSS RS00630
gene id: 758847:LSS_RS00630
uniprot id: K8YEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758847:LSS RS05615
gene id: 758847:LSS_RS05615
uniprot id: K8YGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

758847:LSS RS06550
gene id: 758847:LSS_RS06550
uniprot id: K8XYS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

758847:LSS RS00745
gene id: 758847:LSS_RS00745
uniprot id: K8Y336
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

758847:LSS RS07265
gene id: 758847:LSS_RS07265
uniprot id: K8Y916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

758847:LSS RS16255
gene id: 758847:LSS_RS16255
uniprot id: K8Y174
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

758847:LSS RS10395
gene id: 758847:LSS_RS10395
uniprot id: K8XWC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

758847:LSS RS01450
gene id: 758847:LSS_RS01450
uniprot id: K8Y117
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

758847:LSS RS07540
gene id: 758847:LSS_RS07540
uniprot id: K8Y225
names: Similarity
messages: Belongs to the BolA/IbaG family.

758847:LSS RS13940
gene id: 758847:LSS_RS13940
uniprot id: K8Y3X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

758847:LSS RS01610
gene id: 758847:LSS_RS01610
uniprot id: K8Y2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

758847:LSS RS09245
gene id: 758847:LSS_RS09245
uniprot id: K8Y4Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

758847:LSS RS09305
gene id: 758847:LSS_RS09305
uniprot id: K8XUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

758847:LSS RS14975
gene id: 758847:LSS_RS14975
uniprot id: K8YHW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

758847:LSS RS10315
gene id: 758847:LSS_RS10315
uniprot id: K8XW33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

758847:LSS RS13295
gene id: 758847:LSS_RS13295
uniprot id: K8Y3L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS09455
gene id: 758847:LSS_RS09455
uniprot id: K8XYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

758847:LSS RS10195
gene id: 758847:LSS_RS10195
uniprot id: K8Y4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

758847:LSS RS02700
gene id: 758847:LSS_RS02700
uniprot id: K8Y3R6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

758847:LSS RS05730
gene id: 758847:LSS_RS05730
uniprot id: K8Y637
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

758847:LSS RS17315
gene id: 758847:LSS_RS17315
uniprot id: K8Y0E6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

758847:LSS RS06595
gene id: 758847:LSS_RS06595
uniprot id: K8Y385
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS10980
gene id: 758847:LSS_RS10980
uniprot id: K8YD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

758847:LSS RS11705
gene id: 758847:LSS_RS11705
uniprot id: K8Y611
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758847:LSS RS11935
gene id: 758847:LSS_RS11935
uniprot id: K8XXU1
names: Similarity
messages: Belongs to the universal stress protein A family.

758847:LSS RS10775
gene id: 758847:LSS_RS10775
uniprot id: K8Y3L5
names: Similarity
messages: Belongs to the peptidase S41A family.

758847:LSS RS00705
gene id: 758847:LSS_RS00705
uniprot id: K8YEN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

758847:LSS RS01910
gene id: 758847:LSS_RS01910
uniprot id: K8Y5C5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

758847:LSS RS01275
gene id: 758847:LSS_RS01275
uniprot id: K8Y3M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS03655
gene id: 758847:LSS_RS03655
uniprot id: K8XWU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

758847:LSS RS00125
gene id: 758847:LSS_RS00125
uniprot id: K8XWX4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

758847:LSS RS09210
gene id: 758847:LSS_RS09210
uniprot id: K8XXG3
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS16300
gene id: 758847:LSS_RS16300
uniprot id: K8Y287
names: Similarity
messages: Belongs to the DEAD box helicase family.

758847:LSS RS06265
gene id: 758847:LSS_RS06265
uniprot id: K8XYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

758847:LSS RS00195
gene id: 758847:LSS_RS00195
uniprot id: K8Y8J4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

758847:LSS RS04485
gene id: 758847:LSS_RS04485
uniprot id: K8XXY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

758847:LSS RS11365
gene id: 758847:LSS_RS11365
uniprot id: K8YG51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

758847:LSS RS09765
gene id: 758847:LSS_RS09765
uniprot id: K8Y029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

758847:LSS RS08240
gene id: 758847:LSS_RS08240
uniprot id: K8Y0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

758847:LSS RS04450
gene id: 758847:LSS_RS04450
uniprot id: K8Y7K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

758847:LSS RS11975
gene id: 758847:LSS_RS11975
uniprot id: K8XXA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS01945
gene id: 758847:LSS_RS01945
uniprot id: K8Y5E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

758847:LSS RS03515
gene id: 758847:LSS_RS03515
uniprot id: K8Y3D9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

758847:LSS RS07545
gene id: 758847:LSS_RS07545
uniprot id: K8Y960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

758847:LSS RS03160
gene id: 758847:LSS_RS03160
uniprot id: K8Y5A5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

758847:LSS RS09190
gene id: 758847:LSS_RS09190
uniprot id: K8Y6D2
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS11665
gene id: 758847:LSS_RS11665
uniprot id: K8Y460
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

758847:LSS RS08960
gene id: 758847:LSS_RS08960
uniprot id: K8XZJ3
names: Similarity
messages: Belongs to the enterotoxin A family.

758847:LSS RS11205
gene id: 758847:LSS_RS11205
uniprot id: K8Y3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

758847:LSS RS17160
gene id: 758847:LSS_RS17160
uniprot id: K8Y5E1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

758847:LSS RS16310
gene id: 758847:LSS_RS16310
uniprot id: K8Y406
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758847:LSS RS13870
gene id: 758847:LSS_RS13870
uniprot id: K8Y6F0
names: Similarity
messages: Belongs to the AHA1 family.

758847:LSS RS03370
gene id: 758847:LSS_RS03370
uniprot id: K8Y437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

758847:LSS RS18240
gene id: 758847:LSS_RS18240
uniprot id: K8YA36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758847:LSS RS17210
gene id: 758847:LSS_RS17210
uniprot id: K8YC67
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

758847:LSS RS04645
gene id: 758847:LSS_RS04645
uniprot id: K8XX71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

758847:LSS RS07160
gene id: 758847:LSS_RS07160
uniprot id: K8XUG2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

758847:LSS RS18735
gene id: 758847:LSS_RS18735
uniprot id: K8Y9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS02435
gene id: 758847:LSS_RS02435
uniprot id: K8XVQ3
names: Similarity
messages: Belongs to the aspartokinase family.

758847:LSS RS17115
gene id: 758847:LSS_RS17115
uniprot id: K8XYG5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

758847:LSS RS14915
gene id: 758847:LSS_RS14915
uniprot id: K8Y5C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

758847:LSS RS00025
gene id: 758847:LSS_RS00025
uniprot id: K8Y802
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

758847:LSS RS13730
gene id: 758847:LSS_RS13730
uniprot id: K8YDD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS08735
gene id: 758847:LSS_RS08735
uniprot id: K8XXW9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

758847:LSS RS08985
gene id: 758847:LSS_RS08985
uniprot id: K8Y945
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS01850
gene id: 758847:LSS_RS01850
uniprot id: K8Y2K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

758847:LSS RS18320
gene id: 758847:LSS_RS18320
uniprot id: K8Y5S5
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

758847:LSS RS11970
gene id: 758847:LSS_RS11970
uniprot id: K8XXT2
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14235
gene id: 758847:LSS_RS14235
uniprot id: K8XV11
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758847:LSS RS07530
gene id: 758847:LSS_RS07530
uniprot id: K8Y0M0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

758847:LSS RS09315
gene id: 758847:LSS_RS09315
uniprot id: K8Y2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

758847:LSS RS10305
gene id: 758847:LSS_RS10305
uniprot id: K8XXG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS06785
gene id: 758847:LSS_RS06785
uniprot id: K8XZH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

758847:LSS RS01790
gene id: 758847:LSS_RS01790
uniprot id: K8Y165
names: Similarity
messages: Belongs to the phosphopentomutase family.

758847:LSS RS00575
gene id: 758847:LSS_RS00575
uniprot id: A0A097ERZ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758847:LSS RS16925
gene id: 758847:LSS_RS16925
uniprot id: K8Y327
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

758847:LSS RS17745
gene id: 758847:LSS_RS17745
uniprot id: K8Y1T8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

758847:LSS RS05670
gene id: 758847:LSS_RS05670
uniprot id: K8YGK3
names: Similarity
messages: Belongs to the glutamine synthetase family.

758847:LSS RS08265
gene id: 758847:LSS_RS08265
uniprot id: K8Y7F4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS15280
gene id: 758847:LSS_RS15280
uniprot id: K8Y5I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

758847:LSS RS12080
gene id: 758847:LSS_RS12080
uniprot id: K8XWF0
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS06225
gene id: 758847:LSS_RS06225
uniprot id: K8Y0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

758847:LSS RS08180
gene id: 758847:LSS_RS08180
uniprot id: K8Y087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

758847:LSS RS05845
gene id: 758847:LSS_RS05845
uniprot id: K8XWA5
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

758847:LSS RS06310
gene id: 758847:LSS_RS06310
uniprot id: K8XYN4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758847:LSS RS15920
gene id: 758847:LSS_RS15920
uniprot id: K8YB89
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758847:LSS RS14840
gene id: 758847:LSS_RS14840
uniprot id: K8Y5A8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758847:LSS RS08990
gene id: 758847:LSS_RS08990
uniprot id: K8XY35
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

758847:LSS RS06985
gene id: 758847:LSS_RS06985
uniprot id: K8Y842
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

758847:LSS RS00275
gene id: 758847:LSS_RS00275
uniprot id: K8XXJ7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

758847:LSS RS03500
gene id: 758847:LSS_RS03500
uniprot id: K8XUB0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

758847:LSS RS08520
gene id: 758847:LSS_RS08520
uniprot id: K8XW60
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

758847:LSS RS18455
gene id: 758847:LSS_RS18455
uniprot id: K8Y9N5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

758847:LSS RS13630
gene id: 758847:LSS_RS13630
uniprot id: K8Y3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

758847:LSS RS04555
gene id: 758847:LSS_RS04555
uniprot id: K8Y8N1
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS10650
gene id: 758847:LSS_RS10650
uniprot id: K8XU00
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS01635
gene id: 758847:LSS_RS01635
uniprot id: K8Y2P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS02605
gene id: 758847:LSS_RS02605
uniprot id: K8Y518
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

758847:LSS RS00555
gene id: 758847:LSS_RS00555
uniprot id: K8XVF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS11875
gene id: 758847:LSS_RS11875
uniprot id: K8Y695
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

758847:LSS RS10115
gene id: 758847:LSS_RS10115
uniprot id: A0A097ES68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

758847:LSS RS04665
gene id: 758847:LSS_RS04665
uniprot id: K8Y636
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

758847:LSS RS07965
gene id: 758847:LSS_RS07965
uniprot id: K8Y756
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS15060
gene id: 758847:LSS_RS15060
uniprot id: K8YF03
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

758847:LSS RS15510
gene id: 758847:LSS_RS15510
uniprot id: K8Y0T6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

758847:LSS RS05620
gene id: 758847:LSS_RS05620
uniprot id: K8Y4X9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

758847:LSS RS04565
gene id: 758847:LSS_RS04565
uniprot id: K8Y618
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

758847:LSS RS06710
gene id: 758847:LSS_RS06710
uniprot id: K8XZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

758847:LSS RS14950
gene id: 758847:LSS_RS14950
uniprot id: K8YHV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS03755
gene id: 758847:LSS_RS03755
uniprot id: K8XY68
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

758847:LSS RS17120
gene id: 758847:LSS_RS17120
uniprot id: K8Y823
names: Similarity
messages: Belongs to the ParB family.

758847:LSS RS16520
gene id: 758847:LSS_RS16520
uniprot id: K8YDX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS00155
gene id: 758847:LSS_RS00155
uniprot id: K8XWE3
names: Subcellular Location Annotation
messages: Cytoplasm

758847:LSS RS08150
gene id: 758847:LSS_RS08150
uniprot id: K8YA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

758847:LSS RS17290
gene id: 758847:LSS_RS17290
uniprot id: K8YC52
names: Similarity
messages: Belongs to the ParB family.

758847:LSS RS17865
gene id: 758847:LSS_RS17865
uniprot id: K8YD75
names: Similarity
messages: Belongs to the UDPGP type 1 family.

758847:LSS RS07300
gene id: 758847:LSS_RS07300
uniprot id: K8Y0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

758847:LSS RS10930
gene id: 758847:LSS_RS10930
uniprot id: K8YCZ5
names: Similarity
messages: Belongs to the RemA family.

758847:LSS RS03365
gene id: 758847:LSS_RS03365
uniprot id: K8Y3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758847:LSS RS09450
gene id: 758847:LSS_RS09450
uniprot id: K8Y5W1
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS04800
gene id: 758847:LSS_RS04800
uniprot id: K8XX95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

758847:LSS RS06380
gene id: 758847:LSS_RS06380
uniprot id: K8XZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

758847:LSS RS17505
gene id: 758847:LSS_RS17505
uniprot id: K8Y3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

758847:LSS RS06720
gene id: 758847:LSS_RS06720
uniprot id: K8Y0X7
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS03680
gene id: 758847:LSS_RS03680
uniprot id: K8XWB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

758847:LSS RS05545
gene id: 758847:LSS_RS05545
uniprot id: A0A097ES23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

758847:LSS RS03255
gene id: 758847:LSS_RS03255
uniprot id: K8YCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

758847:LSS RS17240
gene id: 758847:LSS_RS17240
uniprot id: K8YC61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS13920
gene id: 758847:LSS_RS13920
uniprot id: K8XUY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

758847:LSS RS15490
gene id: 758847:LSS_RS15490
uniprot id: K8Y7U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

758847:LSS RS02695
gene id: 758847:LSS_RS02695
uniprot id: K8Y378
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

758847:LSS RS07680
gene id: 758847:LSS_RS07680
uniprot id: K8Y0Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS06840
gene id: 758847:LSS_RS06840
uniprot id: K8XZJ1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758847:LSS RS09010
gene id: 758847:LSS_RS09010
uniprot id: K8Y937
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

758847:LSS RS17840
gene id: 758847:LSS_RS17840
uniprot id: K8YD81
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

758847:LSS RS12005
gene id: 758847:LSS_RS12005
uniprot id: K8XZ68
names: Similarity
messages: Belongs to the pirin family.

758847:LSS RS03375
gene id: 758847:LSS_RS03375
uniprot id: K8YFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

758847:LSS RS14990
gene id: 758847:LSS_RS14990
uniprot id: K8Y5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

758847:LSS RS17765
gene id: 758847:LSS_RS17765
uniprot id: K8YDA2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

758847:LSS RS07355
gene id: 758847:LSS_RS07355
uniprot id: K8YBU9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

758847:LSS RS07605
gene id: 758847:LSS_RS07605
uniprot id: K8Y093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS07700
gene id: 758847:LSS_RS07700
uniprot id: K8Y0A8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

758847:LSS RS14090
gene id: 758847:LSS_RS14090
uniprot id: K8XWG1
names: Subcellular Location Annotation
messages: Periplasmic flagellum

758847:LSS RS11290
gene id: 758847:LSS_RS11290
uniprot id: K8YG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

758847:LSS RS16795
gene id: 758847:LSS_RS16795
uniprot id: K8YAY4
names: Similarity
messages: Belongs to the FrhG family.

758847:LSS RS13670
gene id: 758847:LSS_RS13670
uniprot id: K8YAM8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

758847:LSS RS04035
gene id: 758847:LSS_RS04035
uniprot id: K8Y2E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS12030
gene id: 758847:LSS_RS12030
uniprot id: K8XVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS05735
gene id: 758847:LSS_RS05735
uniprot id: K8YGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

758847:LSS RS10325
gene id: 758847:LSS_RS10325
uniprot id: K8Y4F8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

758847:LSS RS06610
gene id: 758847:LSS_RS06610
uniprot id: K8XW86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS15160
gene id: 758847:LSS_RS15160
uniprot id: K8Y5G0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

758847:LSS RS12310
gene id: 758847:LSS_RS12310
uniprot id: K8Y706
names: Similarity
messages: Belongs to the Fur family.

758847:LSS RS18210
gene id: 758847:LSS_RS18210
uniprot id: K8Y163
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

758847:LSS RS08730
gene id: 758847:LSS_RS08730
uniprot id: K8Y6S5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

758847:LSS RS14560
gene id: 758847:LSS_RS14560
uniprot id: K8Y545
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

758847:LSS RS17130
gene id: 758847:LSS_RS17130
uniprot id: K8XWI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

758847:LSS RS15640
gene id: 758847:LSS_RS15640
uniprot id: K8XZ54
names: Similarity
messages: Belongs to the DprA/Smf family.

758847:LSS RS06515
gene id: 758847:LSS_RS06515
uniprot id: K8Y0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

758847:LSS RS15710
gene id: 758847:LSS_RS15710
uniprot id: K8YAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

758847:LSS RS16530
gene id: 758847:LSS_RS16530
uniprot id: K8Y228
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

758847:LSS RS06995
gene id: 758847:LSS_RS06995
uniprot id: K8XZM9
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

758847:LSS RS16575
gene id: 758847:LSS_RS16575
uniprot id: K8Y216
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

758847:LSS RS13190
gene id: 758847:LSS_RS13190
uniprot id: K8Y7P4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

758847:LSS RS04915
gene id: 758847:LSS_RS04915
uniprot id: K8YE87
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

758847:LSS RS15075
gene id: 758847:LSS_RS15075
uniprot id: K8YHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

758847:LSS RS13445
gene id: 758847:LSS_RS13445
uniprot id: K8Y245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

758847:LSS RS06700
gene id: 758847:LSS_RS06700
uniprot id: K8Y7X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS02075
gene id: 758847:LSS_RS02075
uniprot id: K8XZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

758847:LSS RS07725
gene id: 758847:LSS_RS07725
uniprot id: K8Y0B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS08355
gene id: 758847:LSS_RS08355
uniprot id: K8Y4L8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

758847:LSS RS01720
gene id: 758847:LSS_RS01720
uniprot id: K8Y0U7
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14250
gene id: 758847:LSS_RS14250
uniprot id: K8XX00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758847:LSS RS14420
gene id: 758847:LSS_RS14420
uniprot id: K8Y517
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

758847:LSS RS05450
gene id: 758847:LSS_RS05450
uniprot id: K8Y523
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS18710
gene id: 758847:LSS_RS18710
uniprot id: K8Y9H8
names: Similarity
messages: Belongs to the pyruvate kinase family.

758847:LSS RS08885
gene id: 758847:LSS_RS08885
uniprot id: K8XZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS05625
gene id: 758847:LSS_RS05625
uniprot id: K8Y4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

758847:LSS RS18150
gene id: 758847:LSS_RS18150
uniprot id: K8YCY5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

758847:LSS RS13315
gene id: 758847:LSS_RS13315
uniprot id: K8Y3L6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS16440
gene id: 758847:LSS_RS16440
uniprot id: K8Y249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

758847:LSS RS01770
gene id: 758847:LSS_RS01770
uniprot id: K8Y0T4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

758847:LSS RS10500
gene id: 758847:LSS_RS10500
uniprot id: K8Y4N1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

758847:LSS RS12020
gene id: 758847:LSS_RS12020
uniprot id: K8XXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

758847:LSS RS16840
gene id: 758847:LSS_RS16840
uniprot id: K8Y3P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

758847:LSS RS15960
gene id: 758847:LSS_RS15960
uniprot id: K8Y8G6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

758847:LSS RS13510
gene id: 758847:LSS_RS13510
uniprot id: K8YAQ5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

758847:LSS RS12305
gene id: 758847:LSS_RS12305
uniprot id: K8XXD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

758847:LSS RS14955
gene id: 758847:LSS_RS14955
uniprot id: K8Y7B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

758847:LSS RS07330
gene id: 758847:LSS_RS07330
uniprot id: K8YBU6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

758847:LSS RS09320
gene id: 758847:LSS_RS09320
uniprot id: K8XVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

758847:LSS RS02325
gene id: 758847:LSS_RS02325
uniprot id: K8XZT0
names: Similarity
messages: Belongs to the FGGY kinase family.

758847:LSS RS04715
gene id: 758847:LSS_RS04715
uniprot id: K8Y643
names: Similarity
messages: Belongs to the citrate synthase family.

758847:LSS RS16090
gene id: 758847:LSS_RS16090
uniprot id: K8XZW1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS06325
gene id: 758847:LSS_RS06325
uniprot id: K8Y0F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

758847:LSS RS00190
gene id: 758847:LSS_RS00190
uniprot id: K8XXH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS05105
gene id: 758847:LSS_RS05105
uniprot id: K8Y5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

758847:LSS RS00090
gene id: 758847:LSS_RS00090
uniprot id: K8XYC8
names: Similarity
messages: Belongs to the ArsC family.

758847:LSS RS03150
gene id: 758847:LSS_RS03150
uniprot id: K8Y3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS05250
gene id: 758847:LSS_RS05250
uniprot id: K8YGZ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS03190
gene id: 758847:LSS_RS03190
uniprot id: K8YCN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS09510
gene id: 758847:LSS_RS09510
uniprot id: K8Y8H6
names: Similarity
messages: Belongs to the NTE family.

758847:LSS RS07705
gene id: 758847:LSS_RS07705
uniprot id: K8Y0Q7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

758847:LSS RS18000
gene id: 758847:LSS_RS18000
uniprot id: K8Y320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758847:LSS RS04300
gene id: 758847:LSS_RS04300
uniprot id: K8Y4C7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

758847:LSS RS09630
gene id: 758847:LSS_RS09630
uniprot id: K8Y5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

758847:LSS RS00435
gene id: 758847:LSS_RS00435
uniprot id: K8XZ09
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

758847:LSS RS04145
gene id: 758847:LSS_RS04145
uniprot id: K8YED2
names: Similarity
messages: Belongs to the peptidase M1 family.

758847:LSS RS07515
gene id: 758847:LSS_RS07515
uniprot id: K8Y220
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

758847:LSS RS18185
gene id: 758847:LSS_RS18185
uniprot id: K8Y168
names: Similarity
messages: Belongs to the CobH/CbiC family.

758847:LSS RS02620
gene id: 758847:LSS_RS02620
uniprot id: K8YF98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

758847:LSS RS09055
gene id: 758847:LSS_RS09055
uniprot id: K8Y926
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS07570
gene id: 758847:LSS_RS07570
uniprot id: K8Y230
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS10570
gene id: 758847:LSS_RS10570
uniprot id: K8XW06
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

758847:LSS RS10220
gene id: 758847:LSS_RS10220
uniprot id: K8XVL7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

758847:LSS RS10780
gene id: 758847:LSS_RS10780
uniprot id: K8Y455
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

758847:LSS RS13380
gene id: 758847:LSS_RS13380
uniprot id: K8Y3K2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS00095
gene id: 758847:LSS_RS00095
uniprot id: K8XWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

758847:LSS RS10285
gene id: 758847:LSS_RS10285
uniprot id: K8Y734
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

758847:LSS RS09925
gene id: 758847:LSS_RS09925
uniprot id: K8Y071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS00255
gene id: 758847:LSS_RS00255
uniprot id: K8XX21
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

758847:LSS RS13280
gene id: 758847:LSS_RS13280
uniprot id: K8Y284
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

758847:LSS RS00515
gene id: 758847:LSS_RS00515
uniprot id: K8XUU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

758847:LSS RS00225
gene id: 758847:LSS_RS00225
uniprot id: K8Y5X5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

758847:LSS RS13285
gene id: 758847:LSS_RS13285
uniprot id: K8Y1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

758847:LSS RS07745
gene id: 758847:LSS_RS07745
uniprot id: K8Y997
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758847:LSS RS11855
gene id: 758847:LSS_RS11855
uniprot id: K8XZA3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

758847:LSS RS12690
gene id: 758847:LSS_RS12690
uniprot id: K8Y5P3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

758847:LSS RS03740
gene id: 758847:LSS_RS03740
uniprot id: K8XWS4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

758847:LSS RS13235
gene id: 758847:LSS_RS13235
uniprot id: K8Y294
names: Cofactor
messages: Binds 1 zinc ion per subunit.

758847:LSS RS04920
gene id: 758847:LSS_RS04920
uniprot id: K8Y6N7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

758847:LSS RS14290
gene id: 758847:LSS_RS14290
uniprot id: K8XVL9
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS08330
gene id: 758847:LSS_RS08330
uniprot id: K8Y4M3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

758847:LSS RS10800
gene id: 758847:LSS_RS10800
uniprot id: K8Y459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

758847:LSS RS11895
gene id: 758847:LSS_RS11895
uniprot id: K8XXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

758847:LSS RS16600
gene id: 758847:LSS_RS16600
uniprot id: K8Y209
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS05120
gene id: 758847:LSS_RS05120
uniprot id: K8Y6K0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS00325
gene id: 758847:LSS_RS00325
uniprot id: K8Y5Z4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS08560
gene id: 758847:LSS_RS08560
uniprot id: K8XY39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758847:LSS RS03145
gene id: 758847:LSS_RS03145
uniprot id: K8Y3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS12155
gene id: 758847:LSS_RS12155
uniprot id: K8Y4U5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

758847:LSS RS03590
gene id: 758847:LSS_RS03590
uniprot id: K8XWD8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

758847:LSS RS13130
gene id: 758847:LSS_RS13130
uniprot id: K8XY16
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS17895
gene id: 758847:LSS_RS17895
uniprot id: K8Y1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

758847:LSS RS13935
gene id: 758847:LSS_RS13935
uniprot id: K8XWW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

758847:LSS RS05560
gene id: 758847:LSS_RS05560
uniprot id: K8Y687
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS08465
gene id: 758847:LSS_RS08465
uniprot id: K8Y762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

758847:LSS RS14610
gene id: 758847:LSS_RS14610
uniprot id: K8YEP2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

758847:LSS RS10335
gene id: 758847:LSS_RS10335
uniprot id: K8Y724
names: Similarity
messages: Belongs to the CapA family.

758847:LSS RS01155
gene id: 758847:LSS_RS01155
uniprot id: K8Y3G4
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS04505
gene id: 758847:LSS_RS04505
uniprot id: K8XWI8
names: Similarity
messages: Belongs to the glutamate synthase family.

758847:LSS RS17020
gene id: 758847:LSS_RS17020
uniprot id: K8XWK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

758847:LSS RS11385
gene id: 758847:LSS_RS11385
uniprot id: K8Y4I3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

758847:LSS RS04640
gene id: 758847:LSS_RS04640
uniprot id: K8Y632
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS02250
gene id: 758847:LSS_RS02250
uniprot id: A0A097ES38
names: Similarity
messages: Belongs to the Nudix hydrolase family.

758847:LSS RS14965
gene id: 758847:LSS_RS14965
uniprot id: K8Y5D4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

758847:LSS RS11015
gene id: 758847:LSS_RS11015
uniprot id: K8YFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Membrane

758847:LSS RS09415
gene id: 758847:LSS_RS09415
uniprot id: K8Y5M0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

758847:LSS RS07685
gene id: 758847:LSS_RS07685
uniprot id: K8YC07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

758847:LSS RS11145
gene id: 758847:LSS_RS11145
uniprot id: K8YFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

758847:LSS RS15155
gene id: 758847:LSS_RS15155
uniprot id: K8YEB8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

758847:LSS RS09815
gene id: 758847:LSS_RS09815
uniprot id: K8Y1J1
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14985
gene id: 758847:LSS_RS14985
uniprot id: K8YEY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

758847:LSS RS05075
gene id: 758847:LSS_RS05075
uniprot id: K8YH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS13030
gene id: 758847:LSS_RS13030
uniprot id: K8XY38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

758847:LSS RS02270
gene id: 758847:LSS_RS02270
uniprot id: K8Y9D9
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS13950
gene id: 758847:LSS_RS13950
uniprot id: K8XVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

758847:LSS RS03905
gene id: 758847:LSS_RS03905
uniprot id: K8Y430
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS13960
gene id: 758847:LSS_RS13960
uniprot id: K8XWX5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

758847:LSS RS15880
gene id: 758847:LSS_RS15880
uniprot id: K8Y2V3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS00825
gene id: 758847:LSS_RS00825
uniprot id: K8YBV0
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS07055
gene id: 758847:LSS_RS07055
uniprot id: K8Y149
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

758847:LSS RS12180
gene id: 758847:LSS_RS12180
uniprot id: K8Y4V0
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS06545
gene id: 758847:LSS_RS06545
uniprot id: K8Y7N1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

758847:LSS RS18120
gene id: 758847:LSS_RS18120
uniprot id: K8Y2Z2
names: Similarity
messages: Belongs to the peptidase S1C family.

758847:LSS RS13810
gene id: 758847:LSS_RS13810
uniprot id: K8XUC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

758847:LSS RS13070
gene id: 758847:LSS_RS13070
uniprot id: K8XWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

758847:LSS RS06825
gene id: 758847:LSS_RS06825
uniprot id: K8Y100
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

758847:LSS RS16215
gene id: 758847:LSS_RS16215
uniprot id: K8XZE5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

758847:LSS RS04200
gene id: 758847:LSS_RS04200
uniprot id: K8YEF6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS10640
gene id: 758847:LSS_RS10640
uniprot id: K8Y5Q4
names: Similarity
messages: Belongs to the SCO1/2 family.

758847:LSS RS01265
gene id: 758847:LSS_RS01265
uniprot id: K8Y4Z3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

758847:LSS RS15595
gene id: 758847:LSS_RS15595
uniprot id: K8YAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

758847:LSS RS16405
gene id: 758847:LSS_RS16405
uniprot id: K8Y2J5
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS02380
gene id: 758847:LSS_RS02380
uniprot id: K8XV39
names: Similarity
messages: Belongs to the GARS family.

758847:LSS RS16820
gene id: 758847:LSS_RS16820
uniprot id: K8YAX9
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14875
gene id: 758847:LSS_RS14875
uniprot id: K8YHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

758847:LSS RS17320
gene id: 758847:LSS_RS17320
uniprot id: K8Y9D3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

758847:LSS RS14445
gene id: 758847:LSS_RS14445
uniprot id: K8Y5N8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758847:LSS RS03165
gene id: 758847:LSS_RS03165
uniprot id: K8YCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

758847:LSS RS03495
gene id: 758847:LSS_RS03495
uniprot id: K8Y3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

758847:LSS RS07005
gene id: 758847:LSS_RS07005
uniprot id: K8Y138
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

758847:LSS RS08375
gene id: 758847:LSS_RS08375
uniprot id: K8XVQ5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

758847:LSS RS06535
gene id: 758847:LSS_RS06535
uniprot id: K8YAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

758847:LSS RS14855
gene id: 758847:LSS_RS14855
uniprot id: K8Y788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

758847:LSS RS00905
gene id: 758847:LSS_RS00905
uniprot id: A0A097ES05
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

758847:LSS RS05240
gene id: 758847:LSS_RS05240
uniprot id: K8Y4M9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS09250
gene id: 758847:LSS_RS09250
uniprot id: K8XTS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

758847:LSS RS01930
gene id: 758847:LSS_RS01930
uniprot id: K8Y2T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

758847:LSS RS07390
gene id: 758847:LSS_RS07390
uniprot id: K8Y935
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS18650
gene id: 758847:LSS_RS18650
uniprot id: K8Y0Z7
names: Subcellular Location Annotation
messages: Mitochondrion

758847:LSS RS06810
gene id: 758847:LSS_RS06810
uniprot id: K8XZ46
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS11685
gene id: 758847:LSS_RS11685
uniprot id: K8YDH6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS06500
gene id: 758847:LSS_RS06500
uniprot id: K8XYS1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

758847:LSS RS02545
gene id: 758847:LSS_RS02545
uniprot id: K8Y509
names: Similarity
messages: Belongs to the peptidase S49 family.

758847:LSS RS06745
gene id: 758847:LSS_RS06745
uniprot id: K8Y0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

758847:LSS RS00030
gene id: 758847:LSS_RS00030
uniprot id: K8XWZ8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

758847:LSS RS06585
gene id: 758847:LSS_RS06585
uniprot id: K8Y5T8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS06140
gene id: 758847:LSS_RS06140
uniprot id: K8XWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

758847:LSS RS03875
gene id: 758847:LSS_RS03875
uniprot id: K8Y2A3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758847:LSS RS11325
gene id: 758847:LSS_RS11325
uniprot id: K8YD95
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

758847:LSS RS04610
gene id: 758847:LSS_RS04610
uniprot id: K8XZ23
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS18555
gene id: 758847:LSS_RS18555
uniprot id: K8Y2G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

758847:LSS RS02005
gene id: 758847:LSS_RS02005
uniprot id: K8XY48
names: Similarity
messages: Belongs to the DEAD box helicase family.

758847:LSS RS00300
gene id: 758847:LSS_RS00300
uniprot id: K8XXK0
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS14935
gene id: 758847:LSS_RS14935
uniprot id: K8YEX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

758847:LSS RS17510
gene id: 758847:LSS_RS17510
uniprot id: K8XWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

758847:LSS RS08860
gene id: 758847:LSS_RS08860
uniprot id: K8Y9L2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

758847:LSS RS00885
gene id: 758847:LSS_RS00885
uniprot id: K8Y384
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758847:LSS RS14380
gene id: 758847:LSS_RS14380
uniprot id: K8YHF6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS01580
gene id: 758847:LSS_RS01580
uniprot id: K8Y0Y0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

758847:LSS RS03780
gene id: 758847:LSS_RS03780
uniprot id: K8Y7S0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

758847:LSS RS07320
gene id: 758847:LSS_RS07320
uniprot id: K8Y047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

758847:LSS RS13520
gene id: 758847:LSS_RS13520
uniprot id: K8Y3H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS06600
gene id: 758847:LSS_RS06600
uniprot id: K8XU54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS16955
gene id: 758847:LSS_RS16955
uniprot id: K8XUK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

758847:LSS RS11030
gene id: 758847:LSS_RS11030
uniprot id: K8Y3S2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758847:LSS RS06870
gene id: 758847:LSS_RS06870
uniprot id: K8Y109
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

758847:LSS RS07955
gene id: 758847:LSS_RS07955
uniprot id: K8Y9V5
names: Similarity
messages: Belongs to the thioredoxin family.

758847:LSS RS11920
gene id: 758847:LSS_RS11920
uniprot id: K8Y682
names: Similarity
messages: Belongs to the enterotoxin A family.

758847:LSS RS08350
gene id: 758847:LSS_RS08350
uniprot id: K8XVQ9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

758847:LSS RS10995
gene id: 758847:LSS_RS10995
uniprot id: K8YFV8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

758847:LSS RS10030
gene id: 758847:LSS_RS10030
uniprot id: K8Y098
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

758847:LSS RS12285
gene id: 758847:LSS_RS12285
uniprot id: K8XW16
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

758847:LSS RS10970
gene id: 758847:LSS_RS10970
uniprot id: K8YFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

758847:LSS RS08690
gene id: 758847:LSS_RS08690
uniprot id: K8Y019
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

758847:LSS RS06095
gene id: 758847:LSS_RS06095
uniprot id: K8Y6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

758847:LSS RS05320
gene id: 758847:LSS_RS05320
uniprot id: K8YGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

758847:LSS RS03830
gene id: 758847:LSS_RS03830
uniprot id: K8Y2M7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

758847:LSS RS17820
gene id: 758847:LSS_RS17820
uniprot id: K8Y1R6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758847:LSS RS12100
gene id: 758847:LSS_RS12100
uniprot id: K8XVX0
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

758847:LSS RS00010
gene id: 758847:LSS_RS00010
uniprot id: K8XWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

758847:LSS RS10565
gene id: 758847:LSS_RS10565
uniprot id: K8Y5M3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758847:LSS RS00730
gene id: 758847:LSS_RS00730
uniprot id: K8YEP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS07085
gene id: 758847:LSS_RS07085
uniprot id: K8Y865
names: Similarity
messages: Belongs to the GSP E family.

758847:LSS RS03445
gene id: 758847:LSS_RS03445
uniprot id: K8XTC4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS05160
gene id: 758847:LSS_RS05160
uniprot id: K8YH10
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

758847:LSS RS05155
gene id: 758847:LSS_RS05155
uniprot id: K8Y6J0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

758847:LSS RS07535
gene id: 758847:LSS_RS07535
uniprot id: K8YBY1
names: Similarity
messages: Belongs to the BolA/IbaG family.

758847:LSS RS09420
gene id: 758847:LSS_RS09420
uniprot id: K8XX02
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

758847:LSS RS12380
gene id: 758847:LSS_RS12380
uniprot id: K8XXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

758847:LSS RS06905
gene id: 758847:LSS_RS06905
uniprot id: K8YAS5
names: Similarity
messages: Belongs to the peptidase C40 family.

758847:LSS RS16665
gene id: 758847:LSS_RS16665
uniprot id: K8Y3T0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

758847:LSS RS04950
gene id: 758847:LSS_RS04950
uniprot id: K8YH48
names: Similarity
messages: Belongs to the TrpC family.

758847:LSS RS15475
gene id: 758847:LSS_RS15475
uniprot id: K8XYY6
names: Similarity
messages: Belongs to the Gfa family.

758847:LSS RS10885
gene id: 758847:LSS_RS10885
uniprot id: K8Y3N9
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

758847:LSS RS09380
gene id: 758847:LSS_RS09380
uniprot id: K8Y5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

758847:LSS RS17370
gene id: 758847:LSS_RS17370
uniprot id: K8YC35
names: Similarity
messages: Belongs to the AHA1 family.

758847:LSS RS10175
gene id: 758847:LSS_RS10175
uniprot id: K8Y4I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

758847:LSS RS08540
gene id: 758847:LSS_RS08540
uniprot id: K8Y9N9
names: Similarity
messages: Belongs to the Nth/MutY family.

758847:LSS RS07710
gene id: 758847:LSS_RS07710
uniprot id: K8YC12
names: Similarity
messages: Belongs to the TrpF family.

758847:LSS RS18180
gene id: 758847:LSS_RS18180
uniprot id: K8Y1I0
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

758847:LSS RS10600
gene id: 758847:LSS_RS10600
uniprot id: K8XTX2
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

758847:LSS RS04180
gene id: 758847:LSS_RS04180
uniprot id: K8Y2I1
names: Similarity
messages: Belongs to the AHA1 family.

758847:LSS RS04785
gene id: 758847:LSS_RS04785
uniprot id: K8Y8S0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

758847:LSS RS09360
gene id: 758847:LSS_RS09360
uniprot id: K8XVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

758847:LSS RS01605
gene id: 758847:LSS_RS01605
uniprot id: K8Y9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

758847:LSS RS00720
gene id: 758847:LSS_RS00720
uniprot id: K8Y2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

758847:LSS RS11150
gene id: 758847:LSS_RS11150
uniprot id: K8Y5P0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

758847:LSS RS18635
gene id: 758847:LSS_RS18635
uniprot id: K8Y9J2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

758847:LSS RS14400
gene id: 758847:LSS_RS14400
uniprot id: K8Y5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

758847:LSS RS09400
gene id: 758847:LSS_RS09400
uniprot id: K8XVZ6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS01060
gene id: 758847:LSS_RS01060
uniprot id: K8Y2W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS04650
gene id: 758847:LSS_RS04650
uniprot id: K8XXN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

758847:LSS RS01215
gene id: 758847:LSS_RS01215
uniprot id: K8YF38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS07665
gene id: 758847:LSS_RS07665
uniprot id: K8Y251
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

758847:LSS RS06335
gene id: 758847:LSS_RS06335
uniprot id: K8XYN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

758847:LSS RS07460
gene id: 758847:LSS_RS07460
uniprot id: K8YBW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758847:LSS RS17190
gene id: 758847:LSS_RS17190
uniprot id: K8Y0X5
names: Similarity
messages: Belongs to the ParB family.

758847:LSS RS03630
gene id: 758847:LSS_RS03630
uniprot id: K8XWV4
names: Similarity
messages: Belongs to the UPF0234 family.

758847:LSS RS08595
gene id: 758847:LSS_RS08595
uniprot id: K8Y9Q5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

758847:LSS RS06925
gene id: 758847:LSS_RS06925
uniprot id: K8YAT1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS09875
gene id: 758847:LSS_RS09875
uniprot id: K8Y056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

758847:LSS RS08935
gene id: 758847:LSS_RS08935
uniprot id: K8XZY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

758847:LSS RS03180
gene id: 758847:LSS_RS03180
uniprot id: K8YFJ3
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS11225
gene id: 758847:LSS_RS11225
uniprot id: K8YD70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

758847:LSS RS07275
gene id: 758847:LSS_RS07275
uniprot id: K8Y0G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

758847:LSS RS10240
gene id: 758847:LSS_RS10240
uniprot id: K8XW46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758847:LSS RS11900
gene id: 758847:LSS_RS11900
uniprot id: K8Y686
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

758847:LSS RS16880
gene id: 758847:LSS_RS16880
uniprot id: K8Y319
names: Similarity
messages: Belongs to the glutathione peroxidase family.

758847:LSS RS14190
gene id: 758847:LSS_RS14190
uniprot id: K8Y6I5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758847:LSS RS16445
gene id: 758847:LSS_RS16445
uniprot id: K8YB54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

758847:LSS RS12510
gene id: 758847:LSS_RS12510
uniprot id: K8Y5I8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS06930
gene id: 758847:LSS_RS06930
uniprot id: K8Y123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

758847:LSS RS11230
gene id: 758847:LSS_RS11230
uniprot id: K8Y3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

758847:LSS RS10320
gene id: 758847:LSS_RS10320
uniprot id: K8XVK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

758847:LSS RS05515
gene id: 758847:LSS_RS05515
uniprot id: K8Y501
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

758847:LSS RS03595
gene id: 758847:LSS_RS03595
uniprot id: K8Y589
names: Similarity
messages: Belongs to the TlyA family.

758847:LSS RS09310
gene id: 758847:LSS_RS09310
uniprot id: K8XTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

758847:LSS RS18885
gene id: 758847:LSS_RS18885
uniprot id: K8YBR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

758847:LSS RS11370
gene id: 758847:LSS_RS11370
uniprot id: K8Y5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

758847:LSS RS11870
gene id: 758847:LSS_RS11870
uniprot id: K8XXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

758847:LSS RS15990
gene id: 758847:LSS_RS15990
uniprot id: K8XZY8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS18480
gene id: 758847:LSS_RS18480
uniprot id: K8Y2I3
names: Similarity
messages: Belongs to the glutamate synthase family.

758847:LSS RS07730
gene id: 758847:LSS_RS07730
uniprot id: K8Y0R2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

758847:LSS RS09590
gene id: 758847:LSS_RS09590
uniprot id: K8XWV1
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

758847:LSS RS03715
gene id: 758847:LSS_RS03715
uniprot id: K8XY79
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

758847:LSS RS10225
gene id: 758847:LSS_RS10225
uniprot id: K8Y4H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS14490
gene id: 758847:LSS_RS14490
uniprot id: K8Y5P8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

758847:LSS RS01845
gene id: 758847:LSS_RS01845
uniprot id: K8Y9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

758847:LSS RS04630
gene id: 758847:LSS_RS04630
uniprot id: K8Y8P4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS06525
gene id: 758847:LSS_RS06525
uniprot id: K8XYS5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

758847:LSS RS06145
gene id: 758847:LSS_RS06145
uniprot id: K8Y6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

758847:LSS RS09100
gene id: 758847:LSS_RS09100
uniprot id: K8XZG0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

758847:LSS RS15635
gene id: 758847:LSS_RS15635
uniprot id: K8XYT3
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS13010
gene id: 758847:LSS_RS13010
uniprot id: K8Y512
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

758847:LSS RS14970
gene id: 758847:LSS_RS14970
uniprot id: K8Y5Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

758847:LSS RS08460
gene id: 758847:LSS_RS08460
uniprot id: K8XXJ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

758847:LSS RS17890
gene id: 758847:LSS_RS17890
uniprot id: K8YD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758847:LSS RS08490
gene id: 758847:LSS_RS08490
uniprot id: K8Y759
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

758847:LSS RS09170
gene id: 758847:LSS_RS09170
uniprot id: K8XZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

758847:LSS RS06280
gene id: 758847:LSS_RS06280
uniprot id: K8Y7H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

758847:LSS RS02610
gene id: 758847:LSS_RS02610
uniprot id: K8YCC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS09235
gene id: 758847:LSS_RS09235
uniprot id: K8Y2F2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

758847:LSS RS05700
gene id: 758847:LSS_RS05700
uniprot id: K8YDM5
names: Similarity
messages: Belongs to the RecJ family.

758847:LSS RS10420
gene id: 758847:LSS_RS10420
uniprot id: K8XWB8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

758847:LSS RS01090
gene id: 758847:LSS_RS01090
uniprot id: K8YEZ5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

758847:LSS RS07020
gene id: 758847:LSS_RS07020
uniprot id: K8XZN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

758847:LSS RS06395
gene id: 758847:LSS_RS06395
uniprot id: K8XYP7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

758847:LSS RS03170
gene id: 758847:LSS_RS03170
uniprot id: K8Y3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758847:LSS RS07110
gene id: 758847:LSS_RS07110
uniprot id: K8Y870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

758847:LSS RS06365
gene id: 758847:LSS_RS06365
uniprot id: K8XYP2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

758847:LSS RS17710
gene id: 758847:LSS_RS17710
uniprot id: K8Y4B4
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS07400
gene id: 758847:LSS_RS07400
uniprot id: K8Y0J5
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

758847:LSS RS07675
gene id: 758847:LSS_RS07675
uniprot id: K8Y0A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS05775
gene id: 758847:LSS_RS05775
uniprot id: K8Y625
names: Similarity
messages: Belongs to the histone deacetylase family.

758847:LSS RS18565
gene id: 758847:LSS_RS18565
uniprot id: K8Y116
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

758847:LSS RS14995
gene id: 758847:LSS_RS14995
uniprot id: K8Y602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

758847:LSS RS06285
gene id: 758847:LSS_RS06285
uniprot id: K8XYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

758847:LSS RS03360
gene id: 758847:LSS_RS03360
uniprot id: K8YCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758847:LSS RS15495
gene id: 758847:LSS_RS15495
uniprot id: K8XYZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

758847:LSS RS14925
gene id: 758847:LSS_RS14925
uniprot id: K8YHU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

758847:LSS RS06740
gene id: 758847:LSS_RS06740
uniprot id: K8YAN9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

758847:LSS RS15225
gene id: 758847:LSS_RS15225
uniprot id: K8Y4W7
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

758847:LSS RS07010
gene id: 758847:LSS_RS07010
uniprot id: K8Y849
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

758847:LSS RS03505
gene id: 758847:LSS_RS03505
uniprot id: K8Y5Z3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

758847:LSS RS14645
gene id: 758847:LSS_RS14645
uniprot id: K8Y5S7
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS01350
gene id: 758847:LSS_RS01350
uniprot id: K8Y140
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

758847:LSS RS07715
gene id: 758847:LSS_RS07715
uniprot id: K8Y259
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

758847:LSS RS14670
gene id: 758847:LSS_RS14670
uniprot id: K8YHN5
names: Similarity
messages: Belongs to the threonine synthase family.

758847:LSS RS07500
gene id: 758847:LSS_RS07500
uniprot id: K8Y073
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

758847:LSS RS00490
gene id: 758847:LSS_RS00490
uniprot id: K8Y3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

758847:LSS RS05680
gene id: 758847:LSS_RS05680
uniprot id: K8Y651
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS17025
gene id: 758847:LSS_RS17025
uniprot id: K8Y655
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

758847:LSS RS15705
gene id: 758847:LSS_RS15705
uniprot id: K8XZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

758847:LSS RS02630
gene id: 758847:LSS_RS02630
uniprot id: K8YCC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

758847:LSS RS03985
gene id: 758847:LSS_RS03985
uniprot id: K8YBC6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

758847:LSS RS04795
gene id: 758847:LSS_RS04795
uniprot id: A0A097ES26
names: Similarity
messages: Belongs to the peptidase S1C family.

758847:LSS RS02180
gene id: 758847:LSS_RS02180
uniprot id: K8Y6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

758847:LSS RS05005
gene id: 758847:LSS_RS05005
uniprot id: K8YH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

758847:LSS RS07170
gene id: 758847:LSS_RS07170
uniprot id: K8Y5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

758847:LSS RS02615
gene id: 758847:LSS_RS02615
uniprot id: K8Y361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS02115
gene id: 758847:LSS_RS02115
uniprot id: K8XXQ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

758847:LSS RS11345
gene id: 758847:LSS_RS11345
uniprot id: K8Y5T0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

758847:LSS RS00830
gene id: 758847:LSS_RS00830
uniprot id: K8Y2S4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

758847:LSS RS18235
gene id: 758847:LSS_RS18235
uniprot id: K8Y156
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

758847:LSS RS14485
gene id: 758847:LSS_RS14485
uniprot id: K8Y531
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

758847:LSS RS08445
gene id: 758847:LSS_RS08445
uniprot id: K8XW71
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

758847:LSS RS07180
gene id: 758847:LSS_RS07180
uniprot id: K8Y2Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

758847:LSS RS04130
gene id: 758847:LSS_RS04130
uniprot id: K8Y2H1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS08135
gene id: 758847:LSS_RS08135
uniprot id: K8Y075
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758847:LSS RS02805
gene id: 758847:LSS_RS02805
uniprot id: K8Y393
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

758847:LSS RS07610
gene id: 758847:LSS_RS07610
uniprot id: K8Y0N5
names: Similarity
messages: Belongs to the peptidase S49 family.

758847:LSS RS01255
gene id: 758847:LSS_RS01255
uniprot id: K8Y3L3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

758847:LSS RS02065
gene id: 758847:LSS_RS02065
uniprot id: K8XY65
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS00020
gene id: 758847:LSS_RS00020
uniprot id: K8XYE7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

758847:LSS RS18100
gene id: 758847:LSS_RS18100
uniprot id: K8YCZ8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS17235
gene id: 758847:LSS_RS17235
uniprot id: K8Y2B6
names: Similarity
messages: Belongs to the ALAD family.

758847:LSS RS15825
gene id: 758847:LSS_RS15825
uniprot id: K8XZ99
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

758847:LSS RS14385
gene id: 758847:LSS_RS14385
uniprot id: K8Y6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

758847:LSS RS15200
gene id: 758847:LSS_RS15200
uniprot id: K8Y4W3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

758847:LSS RS08700
gene id: 758847:LSS_RS08700
uniprot id: A0A097ES33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS07090
gene id: 758847:LSS_RS07090
uniprot id: K8XZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

758847:LSS RS13665
gene id: 758847:LSS_RS13665
uniprot id: K8Y1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

758847:LSS RS17755
gene id: 758847:LSS_RS17755
uniprot id: K8YAH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

758847:LSS RS05530
gene id: 758847:LSS_RS05530
uniprot id: K8Y699
names: Similarity
messages: Belongs to the peptidase M24B family.

758847:LSS RS09655
gene id: 758847:LSS_RS09655
uniprot id: K8Y5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

758847:LSS RS14895
gene id: 758847:LSS_RS14895
uniprot id: K8Y5X7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS09585
gene id: 758847:LSS_RS09585
uniprot id: K8XXC6
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS07335
gene id: 758847:LSS_RS07335
uniprot id: K8Y1Y5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

758847:LSS RS10095
gene id: 758847:LSS_RS10095
uniprot id: K8Y0B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS16705
gene id: 758847:LSS_RS16705
uniprot id: K8Y1Y9
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS00005
gene id: 758847:LSS_RS00005
uniprot id: A0A097ES88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

758847:LSS RS07370
gene id: 758847:LSS_RS07370
uniprot id: K8Y052
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

758847:LSS RS08580
gene id: 758847:LSS_RS08580
uniprot id: K8Y6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

758847:LSS RS16475
gene id: 758847:LSS_RS16475
uniprot id: K8YDX8
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS04605
gene id: 758847:LSS_RS04605
uniprot id: K8Y8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

758847:LSS RS18015
gene id: 758847:LSS_RS18015
uniprot id: K8Y1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS06245
gene id: 758847:LSS_RS06245
uniprot id: K8YA77
names: Subcellular Location Annotation
messages: Cytoplasm

758847:LSS RS06955
gene id: 758847:LSS_RS06955
uniprot id: K8Y128
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

758847:LSS RS08230
gene id: 758847:LSS_RS08230
uniprot id: K8XYV8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

758847:LSS RS09285
gene id: 758847:LSS_RS09285
uniprot id: K8Y536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS12215
gene id: 758847:LSS_RS12215
uniprot id: K8XXW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

758847:LSS RS09335
gene id: 758847:LSS_RS09335
uniprot id: K8XTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

758847:LSS RS15000
gene id: 758847:LSS_RS15000
uniprot id: K8YHX1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.

758847:LSS RS14900
gene id: 758847:LSS_RS14900
uniprot id: K8YHU3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

758847:LSS RS02130
gene id: 758847:LSS_RS02130
uniprot id: K8XZN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS14930
gene id: 758847:LSS_RS14930
uniprot id: K8Y7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS01595
gene id: 758847:LSS_RS01595
uniprot id: K8Y1A5
names: Similarity
messages: Belongs to the SCO1/2 family.

758847:LSS RS06830
gene id: 758847:LSS_RS06830
uniprot id: K8Y7Z9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

758847:LSS RS12385
gene id: 758847:LSS_RS12385
uniprot id: K8Y6Z4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

758847:LSS RS14905
gene id: 758847:LSS_RS14905
uniprot id: K8Y7A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

758847:LSS RS06385
gene id: 758847:LSS_RS06385
uniprot id: K8Y0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

758847:LSS RS14980
gene id: 758847:LSS_RS14980
uniprot id: K8Y7C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

758847:LSS RS11890
gene id: 758847:LSS_RS11890
uniprot id: K8XXU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS09045
gene id: 758847:LSS_RS09045
uniprot id: K8Y6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

758847:LSS RS08915
gene id: 758847:LSS_RS08915
uniprot id: K8Y6X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

758847:LSS RS15530
gene id: 758847:LSS_RS15530
uniprot id: K8Y0U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

758847:LSS RS07555
gene id: 758847:LSS_RS07555
uniprot id: K8Y0M5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

758847:LSS RS13460
gene id: 758847:LSS_RS13460
uniprot id: K8Y3I4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS18025
gene id: 758847:LSS_RS18025
uniprot id: K8Y313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

758847:LSS RS10310
gene id: 758847:LSS_RS10310
uniprot id: K8Y728
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

758847:LSS RS14085
gene id: 758847:LSS_RS14085
uniprot id: K8Y3G0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

758847:LSS RS03910
gene id: 758847:LSS_RS03910
uniprot id: K8YBA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

758847:LSS RS14755
gene id: 758847:LSS_RS14755
uniprot id: K8Y767
names: Similarity
messages: Belongs to the glutathione peroxidase family.

758847:LSS RS17475
gene id: 758847:LSS_RS17475
uniprot id: K8Y5Y2
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS15605
gene id: 758847:LSS_RS15605
uniprot id: K8Y7W7
names: Similarity
messages: Belongs to the MotB family.

758847:LSS RS07025
gene id: 758847:LSS_RS07025
uniprot id: K8YAV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

758847:LSS RS16810
gene id: 758847:LSS_RS16810
uniprot id: K8Y2B5
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS09905
gene id: 758847:LSS_RS09905
uniprot id: K8YBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

758847:LSS RS15310
gene id: 758847:LSS_RS15310
uniprot id: K8Y6U6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758847:LSS RS09140
gene id: 758847:LSS_RS09140
uniprot id: K8XXH8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

758847:LSS RS12335
gene id: 758847:LSS_RS12335
uniprot id: K8Y701
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS03625
gene id: 758847:LSS_RS03625
uniprot id: K8Y7W1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

758847:LSS RS11710
gene id: 758847:LSS_RS11710
uniprot id: K8YDI3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758847:LSS RS08420
gene id: 758847:LSS_RS08420
uniprot id: K8XW75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

758847:LSS RS18510
gene id: 758847:LSS_RS18510
uniprot id: K8YCC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758847:LSS RS08115
gene id: 758847:LSS_RS08115
uniprot id: K8Y795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

758847:LSS RS11285
gene id: 758847:LSS_RS11285
uniprot id: K8Y4G3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

758847:LSS RS07340
gene id: 758847:LSS_RS07340
uniprot id: K8Y928
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS16570
gene id: 758847:LSS_RS16570
uniprot id: A0A097ES75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

758847:LSS RS08200
gene id: 758847:LSS_RS08200
uniprot id: K8Y0A1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

758847:LSS RS09000
gene id: 758847:LSS_RS09000
uniprot id: K8Y6G7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

758847:LSS RS12140
gene id: 758847:LSS_RS12140
uniprot id: K8XWG2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

758847:LSS RS12760
gene id: 758847:LSS_RS12760
uniprot id: K8XVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

758847:LSS RS08765
gene id: 758847:LSS_RS08765
uniprot id: K8XYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

758847:LSS RS10755
gene id: 758847:LSS_RS10755
uniprot id: K8Y452
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758847:LSS RS15670
gene id: 758847:LSS_RS15670
uniprot id: K8Y0M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS10330
gene id: 758847:LSS_RS10330
uniprot id: K8XXF7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

758847:LSS RS03155
gene id: 758847:LSS_RS03155
uniprot id: K8YFJ0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

758847:LSS RS09145
gene id: 758847:LSS_RS09145
uniprot id: K8Y6E1
names: Similarity
messages: Belongs to the peptidase U62 family.

758847:LSS RS12750
gene id: 758847:LSS_RS12750
uniprot id: A0A097ES82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

758847:LSS RS01825
gene id: 758847:LSS_RS01825
uniprot id: K8Y2K5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

758847:LSS RS11380
gene id: 758847:LSS_RS11380
uniprot id: K8YDA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

758847:LSS RS02360
gene id: 758847:LSS_RS02360
uniprot id: K8XV32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

758847:LSS RS03615
gene id: 758847:LSS_RS03615
uniprot id: K8Y582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

758847:LSS RS18135
gene id: 758847:LSS_RS18135
uniprot id: K8Y179
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

758847:LSS RS14655
gene id: 758847:LSS_RS14655
uniprot id: K8YEQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758847:LSS RS10950
gene id: 758847:LSS_RS10950
uniprot id: K8Y5J8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

758847:LSS RS01510
gene id: 758847:LSS_RS01510
uniprot id: K8Y1C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758847:LSS RS18465
gene id: 758847:LSS_RS18465
uniprot id: K8Y136
names: Subcellular Location Annotation
messages: Membrane

758847:LSS RS13555
gene id: 758847:LSS_RS13555
uniprot id: K8Y1N2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

758847:LSS RS16625
gene id: 758847:LSS_RS16625
uniprot id: K8Y2F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

758847:LSS RS09935
gene id: 758847:LSS_RS09935
uniprot id: K8Y1L9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

758847:LSS RS08900
gene id: 758847:LSS_RS08900
uniprot id: K8XYH2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

758847:LSS RS04635
gene id: 758847:LSS_RS04635
uniprot id: K8XZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane