756499:DESDE RS12240
gene id: 756499:DESDE_RS12240
uniprot id: I4AA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS07030
gene id: 756499:DESDE_RS07030
uniprot id: I4A7C4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

756499:DESDE RS19845
gene id: 756499:DESDE_RS19845
uniprot id: I4AEF7
names: Similarity
messages: Belongs to the universal stress protein A family.

756499:DESDE RS14895
gene id: 756499:DESDE_RS14895
uniprot id: I4ABN4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

756499:DESDE RS01880
gene id: 756499:DESDE_RS01880
uniprot id: I4A4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

756499:DESDE RS14840
gene id: 756499:DESDE_RS14840
uniprot id: I4ABM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

756499:DESDE RS07090
gene id: 756499:DESDE_RS07090
uniprot id: I4A7D5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS11050
gene id: 756499:DESDE_RS11050
uniprot id: I4A9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

756499:DESDE RS20400
gene id: 756499:DESDE_RS20400
uniprot id: I4AES0
names: Similarity
messages: Belongs to the EutP/PduV family.

756499:DESDE RS12275
gene id: 756499:DESDE_RS12275
uniprot id: I4AA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS01170
gene id: 756499:DESDE_RS01170
uniprot id: I4A433
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

756499:DESDE RS16395
gene id: 756499:DESDE_RS16395
uniprot id: I4ACI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

756499:DESDE RS13575
gene id: 756499:DESDE_RS13575
uniprot id: I4AAX2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

756499:DESDE RS19620
gene id: 756499:DESDE_RS19620
uniprot id: I4AEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

756499:DESDE RS04545
gene id: 756499:DESDE_RS04545
uniprot id: I4A5Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

756499:DESDE RS08960
gene id: 756499:DESDE_RS08960
uniprot id: I4A8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

756499:DESDE RS16805
gene id: 756499:DESDE_RS16805
uniprot id: I4ACR2
names: Similarity
messages: Belongs to the Fur family.

756499:DESDE RS19030
gene id: 756499:DESDE_RS19030
uniprot id: I4ADZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

756499:DESDE RS03885
gene id: 756499:DESDE_RS03885
uniprot id: I4A5K9
names: Similarity
messages: Belongs to the glutamine synthetase family.

756499:DESDE RS04680
gene id: 756499:DESDE_RS04680
uniprot id: I4A610
names: Similarity
messages: Belongs to the SfsA family.

756499:DESDE RS11180
gene id: 756499:DESDE_RS11180
uniprot id: I4A9K6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS00040
gene id: 756499:DESDE_RS00040
uniprot id: I4A3H5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS06125
gene id: 756499:DESDE_RS06125
uniprot id: I4A6V2
names: Similarity
messages: Belongs to the RutC family.

756499:DESDE RS09610
gene id: 756499:DESDE_RS09610
uniprot id: I4A8S3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

756499:DESDE RS14765
gene id: 756499:DESDE_RS14765
uniprot id: I4ABL1
names: Similarity
messages: Belongs to the HypE family.

756499:DESDE RS18195
gene id: 756499:DESDE_RS18195
uniprot id: I4ADI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

756499:DESDE RS01575
gene id: 756499:DESDE_RS01575
uniprot id: I4A4B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

756499:DESDE RS16420
gene id: 756499:DESDE_RS16420
uniprot id: I4ACI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

756499:DESDE RS05555
gene id: 756499:DESDE_RS05555
uniprot id: I4A6I6
names: Similarity
messages: Belongs to the hyi family.

756499:DESDE RS05770
gene id: 756499:DESDE_RS05770
uniprot id: I4A6N0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

756499:DESDE RS19365
gene id: 756499:DESDE_RS19365
uniprot id: I4AE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS16585
gene id: 756499:DESDE_RS16585
uniprot id: I4ACL7
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS14680
gene id: 756499:DESDE_RS14680
uniprot id: I4ABJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

756499:DESDE RS13360
gene id: 756499:DESDE_RS13360
uniprot id: I4AAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

756499:DESDE RS20695
gene id: 756499:DESDE_RS20695
uniprot id: I4AEX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

756499:DESDE RS10830
gene id: 756499:DESDE_RS10830
uniprot id: I4A9D6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

756499:DESDE RS02420
gene id: 756499:DESDE_RS02420
uniprot id: I4A4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS03065
gene id: 756499:DESDE_RS03065
uniprot id: I4A545
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

756499:DESDE RS05635
gene id: 756499:DESDE_RS05635
uniprot id: I4A6K1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

756499:DESDE RS20305
gene id: 756499:DESDE_RS20305
uniprot id: I4AEQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

756499:DESDE RS09645
gene id: 756499:DESDE_RS09645
uniprot id: I4A8T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

756499:DESDE RS03555
gene id: 756499:DESDE_RS03555
uniprot id: I4A5E2
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

756499:DESDE RS20155
gene id: 756499:DESDE_RS20155
uniprot id: I4AEL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

756499:DESDE RS09615
gene id: 756499:DESDE_RS09615
uniprot id: I4A8S4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS08995
gene id: 756499:DESDE_RS08995
uniprot id: I4A8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS00960
gene id: 756499:DESDE_RS00960
uniprot id: I4A3Z3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

756499:DESDE RS18140
gene id: 756499:DESDE_RS18140
uniprot id: I4ADH5
names: Similarity
messages: Belongs to the glutamate synthase family.

756499:DESDE RS13635
gene id: 756499:DESDE_RS13635
uniprot id: I4AAY4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

756499:DESDE RS13840
gene id: 756499:DESDE_RS13840
uniprot id: I4AB24
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS09705
gene id: 756499:DESDE_RS09705
uniprot id: I4A8U4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

756499:DESDE RS12515
gene id: 756499:DESDE_RS12515
uniprot id: I4AAC4
names: Function
names: Similarity
messages: Belongs to the CinA family.
messages: May be involved in the biosynthesis of molybdopterin.

756499:DESDE RS13510
gene id: 756499:DESDE_RS13510
uniprot id: I4AAV9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS01175
gene id: 756499:DESDE_RS01175
uniprot id: I4A434
names: Similarity
messages: Belongs to the MotB family.

756499:DESDE RS11250
gene id: 756499:DESDE_RS11250
uniprot id: I4A9M1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS17525
gene id: 756499:DESDE_RS17525
uniprot id: I4AD53
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

756499:DESDE RS17970
gene id: 756499:DESDE_RS17970
uniprot id: I4ADE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

756499:DESDE RS17095
gene id: 756499:DESDE_RS17095
uniprot id: I4ACX1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

756499:DESDE RS09355
gene id: 756499:DESDE_RS09355
uniprot id: I4A8M0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS20165
gene id: 756499:DESDE_RS20165
uniprot id: I4AEM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

756499:DESDE RS02145
gene id: 756499:DESDE_RS02145
uniprot id: I4A4M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

756499:DESDE RS02665
gene id: 756499:DESDE_RS02665
uniprot id: I4A4W9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

756499:DESDE RS02655
gene id: 756499:DESDE_RS02655
uniprot id: I4A4W7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

756499:DESDE RS15080
gene id: 756499:DESDE_RS15080
uniprot id: I4ABR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

756499:DESDE RS08415
gene id: 756499:DESDE_RS08415
uniprot id: I4A839
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

756499:DESDE RS07935
gene id: 756499:DESDE_RS07935
uniprot id: I4A7U7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

756499:DESDE RS15315
gene id: 756499:DESDE_RS15315
uniprot id: I4ABW7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

756499:DESDE RS06680
gene id: 756499:DESDE_RS06680
uniprot id: I4A760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

756499:DESDE RS20350
gene id: 756499:DESDE_RS20350
uniprot id: I4AER0
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

756499:DESDE RS15075
gene id: 756499:DESDE_RS15075
uniprot id: I4ABR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

756499:DESDE RS02560
gene id: 756499:DESDE_RS02560
uniprot id: I4A4U8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS18090
gene id: 756499:DESDE_RS18090
uniprot id: I4ADG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

756499:DESDE RS00800
gene id: 756499:DESDE_RS00800
uniprot id: I4A3W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

756499:DESDE RS13020
gene id: 756499:DESDE_RS13020
uniprot id: I4AAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS14755
gene id: 756499:DESDE_RS14755
uniprot id: I4ABK9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

756499:DESDE RS06690
gene id: 756499:DESDE_RS06690
uniprot id: I4A762
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

756499:DESDE RS02150
gene id: 756499:DESDE_RS02150
uniprot id: I4A4M2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

756499:DESDE RS06290
gene id: 756499:DESDE_RS06290
uniprot id: I4A6Y4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS01390
gene id: 756499:DESDE_RS01390
uniprot id: I4A473
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS06950
gene id: 756499:DESDE_RS06950
uniprot id: I4A7B2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

756499:DESDE RS16455
gene id: 756499:DESDE_RS16455
uniprot id: I4ACJ6
names: Similarity
messages: Belongs to the pirin family.

756499:DESDE RS02020
gene id: 756499:DESDE_RS02020
uniprot id: I4A4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

756499:DESDE RS03240
gene id: 756499:DESDE_RS03240
uniprot id: I4A579
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

756499:DESDE RS05620
gene id: 756499:DESDE_RS05620
uniprot id: I4A6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

756499:DESDE RS08075
gene id: 756499:DESDE_RS08075
uniprot id: I4A7X5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS08490
gene id: 756499:DESDE_RS08490
uniprot id: I4A851
names: Similarity
messages: Belongs to the UDPGP type 2 family.

756499:DESDE RS01820
gene id: 756499:DESDE_RS01820
uniprot id: I4A4F9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS11505
gene id: 756499:DESDE_RS11505
uniprot id: I4A9R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

756499:DESDE RS13685
gene id: 756499:DESDE_RS13685
uniprot id: I4AAZ2
names: Similarity
messages: Belongs to the UPF0735 family.

756499:DESDE RS05605
gene id: 756499:DESDE_RS05605
uniprot id: I4A6J5
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS06825
gene id: 756499:DESDE_RS06825
uniprot id: I4A787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

756499:DESDE RS14815
gene id: 756499:DESDE_RS14815
uniprot id: I4ABM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS20295
gene id: 756499:DESDE_RS20295
uniprot id: I4AEP8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

756499:DESDE RS20230
gene id: 756499:DESDE_RS20230
uniprot id: I4AEN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS12885
gene id: 756499:DESDE_RS12885
uniprot id: I4AAI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

756499:DESDE RS02710
gene id: 756499:DESDE_RS02710
uniprot id: I4A4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

756499:DESDE RS10615
gene id: 756499:DESDE_RS10615
uniprot id: I4A990
names: Similarity
messages: Belongs to the peptidase S11 family.

756499:DESDE RS15100
gene id: 756499:DESDE_RS15100
uniprot id: I4ABS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

756499:DESDE RS01025
gene id: 756499:DESDE_RS01025
uniprot id: I4A406
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

756499:DESDE RS16755
gene id: 756499:DESDE_RS16755
uniprot id: I4ACQ2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS02140
gene id: 756499:DESDE_RS02140
uniprot id: I4A4M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

756499:DESDE RS10725
gene id: 756499:DESDE_RS10725
uniprot id: I4A9B3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

756499:DESDE RS15645
gene id: 756499:DESDE_RS15645
uniprot id: I4AC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

756499:DESDE RS11980
gene id: 756499:DESDE_RS11980
uniprot id: I4AA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS17055
gene id: 756499:DESDE_RS17055
uniprot id: I4ACW3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS14005
gene id: 756499:DESDE_RS14005
uniprot id: I4AB57
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

756499:DESDE RS12055
gene id: 756499:DESDE_RS12055
uniprot id: I4AA29
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

756499:DESDE RS11545
gene id: 756499:DESDE_RS11545
uniprot id: I4A9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

756499:DESDE RS06935
gene id: 756499:DESDE_RS06935
uniprot id: I4A7A9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

756499:DESDE RS17290
gene id: 756499:DESDE_RS17290
uniprot id: I4AD09
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS12435
gene id: 756499:DESDE_RS12435
uniprot id: I4AAA8
names: Similarity
messages: Belongs to the peptidase S58 family.

756499:DESDE RS09455
gene id: 756499:DESDE_RS09455
uniprot id: I4A8P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS01690
gene id: 756499:DESDE_RS01690
uniprot id: I4A4D2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS10275
gene id: 756499:DESDE_RS10275
uniprot id: I4A928
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

756499:DESDE RS08945
gene id: 756499:DESDE_RS08945
uniprot id: I4A8E2
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS03340
gene id: 756499:DESDE_RS03340
uniprot id: I4A597
names: Similarity
messages: Belongs to the CapA family.

756499:DESDE RS14910
gene id: 756499:DESDE_RS14910
uniprot id: I4ABN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

756499:DESDE RS01780
gene id: 756499:DESDE_RS01780
uniprot id: I4A4F1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

756499:DESDE RS11110
gene id: 756499:DESDE_RS11110
uniprot id: I4A9J3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS14775
gene id: 756499:DESDE_RS14775
uniprot id: I4ABL3
names: Similarity
messages: Belongs to the HupF/HypC family.

756499:DESDE RS07485
gene id: 756499:DESDE_RS07485
uniprot id: I4A7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

756499:DESDE RS03960
gene id: 756499:DESDE_RS03960
uniprot id: I4A5M2
names: Similarity
messages: Belongs to the TPP enzyme family.

756499:DESDE RS09340
gene id: 756499:DESDE_RS09340
uniprot id: I4A8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS20415
gene id: 756499:DESDE_RS20415
uniprot id: I4AES2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

756499:DESDE RS09875
gene id: 756499:DESDE_RS09875
uniprot id: I4A8X6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS15620
gene id: 756499:DESDE_RS15620
uniprot id: I4AC28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS09975
gene id: 756499:DESDE_RS09975
uniprot id: I4A8Z6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

756499:DESDE RS03245
gene id: 756499:DESDE_RS03245
uniprot id: I4A580
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

756499:DESDE RS17885
gene id: 756499:DESDE_RS17885
uniprot id: I4ADC4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13370
gene id: 756499:DESDE_RS13370
uniprot id: I4AAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS03295
gene id: 756499:DESDE_RS03295
uniprot id: I4A589
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS20125
gene id: 756499:DESDE_RS20125
uniprot id: I4AEL3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

756499:DESDE RS13695
gene id: 756499:DESDE_RS13695
uniprot id: I4AAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

756499:DESDE RS05945
gene id: 756499:DESDE_RS05945
uniprot id: I4A6R6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

756499:DESDE RS15400
gene id: 756499:DESDE_RS15400
uniprot id: I4ABY5
names: Similarity
messages: Belongs to the peptidase A24 family.

756499:DESDE RS03330
gene id: 756499:DESDE_RS03330
uniprot id: I4A595
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS12860
gene id: 756499:DESDE_RS12860
uniprot id: I4AAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

756499:DESDE RS14540
gene id: 756499:DESDE_RS14540
uniprot id: I4ABG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS00955
gene id: 756499:DESDE_RS00955
uniprot id: I4A3Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

756499:DESDE RS13040
gene id: 756499:DESDE_RS13040
uniprot id: I4AAL5
names: Similarity
messages: Belongs to the UPF0178 family.

756499:DESDE RS10045
gene id: 756499:DESDE_RS10045
uniprot id: I4A910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS06910
gene id: 756499:DESDE_RS06910
uniprot id: I4A7A4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

756499:DESDE RS18335
gene id: 756499:DESDE_RS18335
uniprot id: I4ADL0
names: Similarity
messages: Belongs to the class-I fumarase family.

756499:DESDE RS14695
gene id: 756499:DESDE_RS14695
uniprot id: I4ABJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

756499:DESDE RS03485
gene id: 756499:DESDE_RS03485
uniprot id: I4A5C8
names: Similarity
messages: Belongs to the GerABKA family.

756499:DESDE RS10515
gene id: 756499:DESDE_RS10515
uniprot id: I4A970
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01770
gene id: 756499:DESDE_RS01770
uniprot id: I4A4E9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

756499:DESDE RS18250
gene id: 756499:DESDE_RS18250
uniprot id: I4ADJ6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

756499:DESDE RS09000
gene id: 756499:DESDE_RS09000
uniprot id: I4A8F3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

756499:DESDE RS01055
gene id: 756499:DESDE_RS01055
uniprot id: I4A412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS15630
gene id: 756499:DESDE_RS15630
uniprot id: I4AC30
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS06810
gene id: 756499:DESDE_RS06810
uniprot id: I4A784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

756499:DESDE RS02880
gene id: 756499:DESDE_RS02880
uniprot id: I4A507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

756499:DESDE RS01865
gene id: 756499:DESDE_RS01865
uniprot id: I4A4G8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS18345
gene id: 756499:DESDE_RS18345
uniprot id: I4ADL2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

756499:DESDE RS16465
gene id: 756499:DESDE_RS16465
uniprot id: I4ACJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

756499:DESDE RS05640
gene id: 756499:DESDE_RS05640
uniprot id: I4A6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

756499:DESDE RS08735
gene id: 756499:DESDE_RS08735
uniprot id: I4A8A0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS02015
gene id: 756499:DESDE_RS02015
uniprot id: I4A4J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

756499:DESDE RS00235
gene id: 756499:DESDE_RS00235
uniprot id: I4A3L0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

756499:DESDE RS07480
gene id: 756499:DESDE_RS07480
uniprot id: I4A7K8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS08625
gene id: 756499:DESDE_RS08625
uniprot id: I4A878
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

756499:DESDE RS14720
gene id: 756499:DESDE_RS14720
uniprot id: I4ABK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

756499:DESDE RS20575
gene id: 756499:DESDE_RS20575
uniprot id: I4AEV2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

756499:DESDE RS19140
gene id: 756499:DESDE_RS19140
uniprot id: I4AE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS01470
gene id: 756499:DESDE_RS01470
uniprot id: I4A489
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

756499:DESDE RS19745
gene id: 756499:DESDE_RS19745
uniprot id: I4AED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

756499:DESDE RS11160
gene id: 756499:DESDE_RS11160
uniprot id: I4A9K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

756499:DESDE RS03875
gene id: 756499:DESDE_RS03875
uniprot id: I4A5K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

756499:DESDE RS10835
gene id: 756499:DESDE_RS10835
uniprot id: I4A9D7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

756499:DESDE RS13110
gene id: 756499:DESDE_RS13110
uniprot id: I4AAN0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

756499:DESDE RS03520
gene id: 756499:DESDE_RS03520
uniprot id: I4A5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

756499:DESDE RS15635
gene id: 756499:DESDE_RS15635
uniprot id: I4AC31
names: Similarity
messages: Belongs to the UPF0102 family.

756499:DESDE RS02305
gene id: 756499:DESDE_RS02305
uniprot id: I4A4Q1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS06310
gene id: 756499:DESDE_RS06310
uniprot id: I4A6Y8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13770
gene id: 756499:DESDE_RS13770
uniprot id: I4AB09
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

756499:DESDE RS02480
gene id: 756499:DESDE_RS02480
uniprot id: I4A4T2
names: Subcellular Location Annotation
messages: Cell membrane

756499:DESDE RS04780
gene id: 756499:DESDE_RS04780
uniprot id: I4A629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS16385
gene id: 756499:DESDE_RS16385
uniprot id: I4ACI2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

756499:DESDE RS03740
gene id: 756499:DESDE_RS03740
uniprot id: I4A5I0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS02425
gene id: 756499:DESDE_RS02425
uniprot id: I4A4S1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS05735
gene id: 756499:DESDE_RS05735
uniprot id: I4A6M3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

756499:DESDE RS10645
gene id: 756499:DESDE_RS10645
uniprot id: I4A996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS02200
gene id: 756499:DESDE_RS02200
uniprot id: I4A4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

756499:DESDE RS00615
gene id: 756499:DESDE_RS00615
uniprot id: I4A3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

756499:DESDE RS17245
gene id: 756499:DESDE_RS17245
uniprot id: I4AD00
names: Similarity
messages: Belongs to the FlgM family.

756499:DESDE RS13815
gene id: 756499:DESDE_RS13815
uniprot id: I4AB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

756499:DESDE RS12225
gene id: 756499:DESDE_RS12225
uniprot id: I4AA64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

756499:DESDE RS18560
gene id: 756499:DESDE_RS18560
uniprot id: I4ADQ5
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

756499:DESDE RS00030
gene id: 756499:DESDE_RS00030
uniprot id: I4A3H3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

756499:DESDE RS14185
gene id: 756499:DESDE_RS14185
uniprot id: I4AB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

756499:DESDE RS16680
gene id: 756499:DESDE_RS16680
uniprot id: I4ACN7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS18890
gene id: 756499:DESDE_RS18890
uniprot id: I4ADW9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19125
gene id: 756499:DESDE_RS19125
uniprot id: I4AE16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

756499:DESDE RS18940
gene id: 756499:DESDE_RS18940
uniprot id: I4ADX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

756499:DESDE RS10735
gene id: 756499:DESDE_RS10735
uniprot id: I4A9B5
names: Similarity
messages: Belongs to the peptidase S11 family.

756499:DESDE RS09640
gene id: 756499:DESDE_RS09640
uniprot id: I4A8S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

756499:DESDE RS01335
gene id: 756499:DESDE_RS01335
uniprot id: I4A462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

756499:DESDE RS03975
gene id: 756499:DESDE_RS03975
uniprot id: I4A5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

756499:DESDE RS16225
gene id: 756499:DESDE_RS16225
uniprot id: I4ACE9
names: Similarity
messages: Belongs to the RemA family.

756499:DESDE RS06830
gene id: 756499:DESDE_RS06830
uniprot id: I4A788
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

756499:DESDE RS09965
gene id: 756499:DESDE_RS09965
uniprot id: I4A8Z4
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

756499:DESDE RS18120
gene id: 756499:DESDE_RS18120
uniprot id: I4ADH1
names: Similarity
messages: Belongs to the UPF0111 family.

756499:DESDE RS17935
gene id: 756499:DESDE_RS17935
uniprot id: I4ADD4
names: Similarity
messages: Belongs to the MtrH family.

756499:DESDE RS06945
gene id: 756499:DESDE_RS06945
uniprot id: I4A7B1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

756499:DESDE RS10060
gene id: 756499:DESDE_RS10060
uniprot id: I4A913
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13895
gene id: 756499:DESDE_RS13895
uniprot id: I4AB35
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

756499:DESDE RS04350
gene id: 756499:DESDE_RS04350
uniprot id: I4A5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS06670
gene id: 756499:DESDE_RS06670
uniprot id: I4A758
names: Similarity
messages: Belongs to the SAICAR synthetase family.

756499:DESDE RS14990
gene id: 756499:DESDE_RS14990
uniprot id: I4ABQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS08125
gene id: 756499:DESDE_RS08125
uniprot id: I4A7Y5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19890
gene id: 756499:DESDE_RS19890
uniprot id: I4AEG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

756499:DESDE RS14870
gene id: 756499:DESDE_RS14870
uniprot id: I4ABM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

756499:DESDE RS20670
gene id: 756499:DESDE_RS20670
uniprot id: I4AEX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

756499:DESDE RS09405
gene id: 756499:DESDE_RS09405
uniprot id: I4A8N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

756499:DESDE RS18015
gene id: 756499:DESDE_RS18015
uniprot id: I4ADF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

756499:DESDE RS00640
gene id: 756499:DESDE_RS00640
uniprot id: I4A3T9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

756499:DESDE RS19205
gene id: 756499:DESDE_RS19205
uniprot id: I4AE32
names: Similarity
messages: Belongs to the universal stress protein A family.

756499:DESDE RS20360
gene id: 756499:DESDE_RS20360
uniprot id: I4AER2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS15615
gene id: 756499:DESDE_RS15615
uniprot id: I4AC27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS05930
gene id: 756499:DESDE_RS05930
uniprot id: I4A6R3
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS08655
gene id: 756499:DESDE_RS08655
uniprot id: I4A884
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

756499:DESDE RS15870
gene id: 756499:DESDE_RS15870
uniprot id: I4AC77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

756499:DESDE RS03940
gene id: 756499:DESDE_RS03940
uniprot id: I4A5L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS13890
gene id: 756499:DESDE_RS13890
uniprot id: I4AB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS09905
gene id: 756499:DESDE_RS09905
uniprot id: I4A8Y2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

756499:DESDE RS17880
gene id: 756499:DESDE_RS17880
uniprot id: I4ADC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

756499:DESDE RS06835
gene id: 756499:DESDE_RS06835
uniprot id: I4A789
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

756499:DESDE RS18735
gene id: 756499:DESDE_RS18735
uniprot id: I4ADT7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

756499:DESDE RS13960
gene id: 756499:DESDE_RS13960
uniprot id: I4AB48
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

756499:DESDE RS08405
gene id: 756499:DESDE_RS08405
uniprot id: I4A837
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

756499:DESDE RS11880
gene id: 756499:DESDE_RS11880
uniprot id: I4A9Z4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

756499:DESDE RS07060
gene id: 756499:DESDE_RS07060
uniprot id: I4A7D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS06065
gene id: 756499:DESDE_RS06065
uniprot id: I4A6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

756499:DESDE RS14730
gene id: 756499:DESDE_RS14730
uniprot id: I4ABK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

756499:DESDE RS20680
gene id: 756499:DESDE_RS20680
uniprot id: I4AEX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS03985
gene id: 756499:DESDE_RS03985
uniprot id: I4A5M7
names: Similarity
messages: Belongs to the glutamate synthase family.

756499:DESDE RS19570
gene id: 756499:DESDE_RS19570
uniprot id: I4AEA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

756499:DESDE RS16390
gene id: 756499:DESDE_RS16390
uniprot id: I4ACI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS05585
gene id: 756499:DESDE_RS05585
uniprot id: I4A6J1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

756499:DESDE RS17060
gene id: 756499:DESDE_RS17060
uniprot id: I4ACW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

756499:DESDE RS07945
gene id: 756499:DESDE_RS07945
uniprot id: I4A7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS19260
gene id: 756499:DESDE_RS19260
uniprot id: I4AE43
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16705
gene id: 756499:DESDE_RS16705
uniprot id: I4ACP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

756499:DESDE RS01900
gene id: 756499:DESDE_RS01900
uniprot id: I4A4H5
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

756499:DESDE RS20245
gene id: 756499:DESDE_RS20245
uniprot id: I4AEN8
names: Similarity
messages: Belongs to the SleB family.

756499:DESDE RS03835
gene id: 756499:DESDE_RS03835
uniprot id: I4A5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS10760
gene id: 756499:DESDE_RS10760
uniprot id: I4A9C0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

756499:DESDE RS16700
gene id: 756499:DESDE_RS16700
uniprot id: I4ACP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

756499:DESDE RS13645
gene id: 756499:DESDE_RS13645
uniprot id: I4AAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

756499:DESDE RS03445
gene id: 756499:DESDE_RS03445
uniprot id: I4A5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

756499:DESDE RS16915
gene id: 756499:DESDE_RS16915
uniprot id: I4ACT5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

756499:DESDE RS07285
gene id: 756499:DESDE_RS07285
uniprot id: I4A7H3
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

756499:DESDE RS01875
gene id: 756499:DESDE_RS01875
uniprot id: I4A4H0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS16275
gene id: 756499:DESDE_RS16275
uniprot id: I4ACF8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

756499:DESDE RS18295
gene id: 756499:DESDE_RS18295
uniprot id: I4ADK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

756499:DESDE RS03010
gene id: 756499:DESDE_RS03010
uniprot id: I4A534
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

756499:DESDE RS16290
gene id: 756499:DESDE_RS16290
uniprot id: I4ACG2
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12495
gene id: 756499:DESDE_RS12495
uniprot id: I4AAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

756499:DESDE RS10590
gene id: 756499:DESDE_RS10590
uniprot id: I4A985
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS03040
gene id: 756499:DESDE_RS03040
uniprot id: I4A540
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.

756499:DESDE RS15685
gene id: 756499:DESDE_RS15685
uniprot id: I4AC41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS11165
gene id: 756499:DESDE_RS11165
uniprot id: I4A9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

756499:DESDE RS18690
gene id: 756499:DESDE_RS18690
uniprot id: I4ADS9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

756499:DESDE RS06270
gene id: 756499:DESDE_RS06270
uniprot id: I4A6Y1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01930
gene id: 756499:DESDE_RS01930
uniprot id: I4A4I1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

756499:DESDE RS13930
gene id: 756499:DESDE_RS13930
uniprot id: I4AB42
names: Similarity
messages: Belongs to the GerABKA family.

756499:DESDE RS09095
gene id: 756499:DESDE_RS09095
uniprot id: I4A8H0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

756499:DESDE RS20220
gene id: 756499:DESDE_RS20220
uniprot id: I4AEN2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS03670
gene id: 756499:DESDE_RS03670
uniprot id: I4A5G5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS05700
gene id: 756499:DESDE_RS05700
uniprot id: I4A6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

756499:DESDE RS15035
gene id: 756499:DESDE_RS15035
uniprot id: I4ABR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

756499:DESDE RS19860
gene id: 756499:DESDE_RS19860
uniprot id: I4AEG0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS18100
gene id: 756499:DESDE_RS18100
uniprot id: I4ADG7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

756499:DESDE RS08750
gene id: 756499:DESDE_RS08750
uniprot id: I4A8A3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

756499:DESDE RS03110
gene id: 756499:DESDE_RS03110
uniprot id: I4A553
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

756499:DESDE RS09710
gene id: 756499:DESDE_RS09710
uniprot id: I4A8U5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16750
gene id: 756499:DESDE_RS16750
uniprot id: I4ACQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

756499:DESDE RS02165
gene id: 756499:DESDE_RS02165
uniprot id: I4A4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

756499:DESDE RS17565
gene id: 756499:DESDE_RS17565
uniprot id: I4AD61
names: Similarity
messages: Belongs to the UPF0751 family.

756499:DESDE RS14100
gene id: 756499:DESDE_RS14100
uniprot id: I4AB78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

756499:DESDE RS04475
gene id: 756499:DESDE_RS04475
uniprot id: I4A5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

756499:DESDE RS05965
gene id: 756499:DESDE_RS05965
uniprot id: I4A6S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

756499:DESDE RS09540
gene id: 756499:DESDE_RS09540
uniprot id: I4A8Q9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

756499:DESDE RS02055
gene id: 756499:DESDE_RS02055
uniprot id: I4A4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

756499:DESDE RS03590
gene id: 756499:DESDE_RS03590
uniprot id: I4A5E9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10675
gene id: 756499:DESDE_RS10675
uniprot id: I4A9A2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

756499:DESDE RS14850
gene id: 756499:DESDE_RS14850
uniprot id: I4ABM5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

756499:DESDE RS14265
gene id: 756499:DESDE_RS14265
uniprot id: I4ABA8
names: Similarity
messages: Belongs to the asp23 family.

756499:DESDE RS02635
gene id: 756499:DESDE_RS02635
uniprot id: I4A4W3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

756499:DESDE RS15970
gene id: 756499:DESDE_RS15970
uniprot id: I4AC97
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

756499:DESDE RS08025
gene id: 756499:DESDE_RS08025
uniprot id: I4A7W5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

756499:DESDE RS04595
gene id: 756499:DESDE_RS04595
uniprot id: I4A5Z3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

756499:DESDE RS00700
gene id: 756499:DESDE_RS00700
uniprot id: I4A3U5
names: Similarity
messages: Belongs to the DltD family.

756499:DESDE RS08055
gene id: 756499:DESDE_RS08055
uniprot id: I4A7X1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS05580
gene id: 756499:DESDE_RS05580
uniprot id: I4A6J0
names: Subunit
messages: Homotetramer.

756499:DESDE RS20630
gene id: 756499:DESDE_RS20630
uniprot id: I4AEW3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

756499:DESDE RS12120
gene id: 756499:DESDE_RS12120
uniprot id: I4AA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

756499:DESDE RS07010
gene id: 756499:DESDE_RS07010
uniprot id: I4A7C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS06715
gene id: 756499:DESDE_RS06715
uniprot id: I4A767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

756499:DESDE RS02700
gene id: 756499:DESDE_RS02700
uniprot id: I4A4X7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

756499:DESDE RS05755
gene id: 756499:DESDE_RS05755
uniprot id: I4A6M7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

756499:DESDE RS17035
gene id: 756499:DESDE_RS17035
uniprot id: U3GJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

756499:DESDE RS18950
gene id: 756499:DESDE_RS18950
uniprot id: I4ADY1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16025
gene id: 756499:DESDE_RS16025
uniprot id: I4ACA8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12090
gene id: 756499:DESDE_RS12090
uniprot id: I4AA36
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS05660
gene id: 756499:DESDE_RS05660
uniprot id: I4A6K6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

756499:DESDE RS06635
gene id: 756499:DESDE_RS06635
uniprot id: I4A751
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

756499:DESDE RS20140
gene id: 756499:DESDE_RS20140
uniprot id: I4AEL6
names: Similarity
messages: Belongs to the UPF0340 family.

756499:DESDE RS01460
gene id: 756499:DESDE_RS01460
uniprot id: I4A487
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS14325
gene id: 756499:DESDE_RS14325
uniprot id: I4ABC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

756499:DESDE RS18770
gene id: 756499:DESDE_RS18770
uniprot id: I4ADU4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

756499:DESDE RS17780
gene id: 756499:DESDE_RS17780
uniprot id: I4ADA3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

756499:DESDE RS00465
gene id: 756499:DESDE_RS00465
uniprot id: I4A3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

756499:DESDE RS16715
gene id: 756499:DESDE_RS16715
uniprot id: I4ACP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS08790
gene id: 756499:DESDE_RS08790
uniprot id: I4A8B1
names: Similarity
messages: Belongs to the ArsC family.

756499:DESDE RS20660
gene id: 756499:DESDE_RS20660
uniprot id: I4AEW9
names: Similarity
messages: Belongs to the ParB family.

756499:DESDE RS00685
gene id: 756499:DESDE_RS00685
uniprot id: I4A3U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS01330
gene id: 756499:DESDE_RS01330
uniprot id: I4A461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS17145
gene id: 756499:DESDE_RS17145
uniprot id: I4ACY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

756499:DESDE RS12935
gene id: 756499:DESDE_RS12935
uniprot id: I4AAJ5
names: Similarity
messages: Belongs to the YciI family.

756499:DESDE RS14145
gene id: 756499:DESDE_RS14145
uniprot id: I4AB87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

756499:DESDE RS01510
gene id: 756499:DESDE_RS01510
uniprot id: I4A497
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

756499:DESDE RS15235
gene id: 756499:DESDE_RS15235
uniprot id: I4ABV1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

756499:DESDE RS01910
gene id: 756499:DESDE_RS01910
uniprot id: I4A4H7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

756499:DESDE RS11735
gene id: 756499:DESDE_RS11735
uniprot id: I4A9W3
names: Similarity
messages: Belongs to the RutC family.

756499:DESDE RS00505
gene id: 756499:DESDE_RS00505
uniprot id: I4A3R3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

756499:DESDE RS06040
gene id: 756499:DESDE_RS06040
uniprot id: I4A6T3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

756499:DESDE RS20555
gene id: 756499:DESDE_RS20555
uniprot id: I4AEU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

756499:DESDE RS01110
gene id: 756499:DESDE_RS01110
uniprot id: I4A420
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01725
gene id: 756499:DESDE_RS01725
uniprot id: I4A4E0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS20145
gene id: 756499:DESDE_RS20145
uniprot id: I4AEL7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

756499:DESDE RS05045
gene id: 756499:DESDE_RS05045
uniprot id: I4A682
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

756499:DESDE RS11520
gene id: 756499:DESDE_RS11520
uniprot id: I4A9R9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS17350
gene id: 756499:DESDE_RS17350
uniprot id: I4AD19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

756499:DESDE RS17420
gene id: 756499:DESDE_RS17420
uniprot id: I4AD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS14745
gene id: 756499:DESDE_RS14745
uniprot id: I4ABK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

756499:DESDE RS16735
gene id: 756499:DESDE_RS16735
uniprot id: I4ACP8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS04805
gene id: 756499:DESDE_RS04805
uniprot id: I4A634
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

756499:DESDE RS18060
gene id: 756499:DESDE_RS18060
uniprot id: I4ADF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

756499:DESDE RS14685
gene id: 756499:DESDE_RS14685
uniprot id: I4ABJ5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

756499:DESDE RS05570
gene id: 756499:DESDE_RS05570
uniprot id: I4A6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

756499:DESDE RS00945
gene id: 756499:DESDE_RS00945
uniprot id: I4A3Z0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

756499:DESDE RS19815
gene id: 756499:DESDE_RS19815
uniprot id: I4AEF0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

756499:DESDE RS04685
gene id: 756499:DESDE_RS04685
uniprot id: I4A611
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

756499:DESDE RS18065
gene id: 756499:DESDE_RS18065
uniprot id: I4ADG0
names: Similarity
messages: Belongs to the transpeptidase family.

756499:DESDE RS14690
gene id: 756499:DESDE_RS14690
uniprot id: I4ABJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

756499:DESDE RS01220
gene id: 756499:DESDE_RS01220
uniprot id: I4A438
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

756499:DESDE RS19585
gene id: 756499:DESDE_RS19585
uniprot id: I4AEA7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

756499:DESDE RS14565
gene id: 756499:DESDE_RS14565
uniprot id: I4ABG9
names: Similarity
messages: Belongs to the thioredoxin family.

756499:DESDE RS15015
gene id: 756499:DESDE_RS15015
uniprot id: I4ABQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS11440
gene id: 756499:DESDE_RS11440
uniprot id: I4A9Q3
names: Similarity
messages: Belongs to the peptidase M29 family.

756499:DESDE RS12755
gene id: 756499:DESDE_RS12755
uniprot id: I4AAG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS19810
gene id: 756499:DESDE_RS19810
uniprot id: I4AEE9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

756499:DESDE RS17775
gene id: 756499:DESDE_RS17775
uniprot id: I4ADA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

756499:DESDE RS01140
gene id: 756499:DESDE_RS01140
uniprot id: I4A426
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS16780
gene id: 756499:DESDE_RS16780
uniprot id: I4ACQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

756499:DESDE RS12700
gene id: 756499:DESDE_RS12700
uniprot id: I4AAG0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

756499:DESDE RS15705
gene id: 756499:DESDE_RS15705
uniprot id: I4AC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18180
gene id: 756499:DESDE_RS18180
uniprot id: I4ADI3
names: Similarity
messages: Belongs to the TrpF family.

756499:DESDE RS10690
gene id: 756499:DESDE_RS10690
uniprot id: I4A9A5
names: Similarity
messages: Belongs to the histone deacetylase family.

756499:DESDE RS14885
gene id: 756499:DESDE_RS14885
uniprot id: I4ABN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

756499:DESDE RS14650
gene id: 756499:DESDE_RS14650
uniprot id: I4ABI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS12745
gene id: 756499:DESDE_RS12745
uniprot id: I4AAG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS07565
gene id: 756499:DESDE_RS07565
uniprot id: I4A7M4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12645
gene id: 756499:DESDE_RS12645
uniprot id: I4AAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS20020
gene id: 756499:DESDE_RS20020
uniprot id: I4AEJ2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

756499:DESDE RS01580
gene id: 756499:DESDE_RS01580
uniprot id: I4A4B1
names: Subcellular Location Annotation
messages: Periplasm

756499:DESDE RS05560
gene id: 756499:DESDE_RS05560
uniprot id: I4A6I7
names: Similarity
messages: Belongs to the TPP enzyme family.

756499:DESDE RS00635
gene id: 756499:DESDE_RS00635
uniprot id: I4A3T8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

756499:DESDE RS00605
gene id: 756499:DESDE_RS00605
uniprot id: I4A3T2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

756499:DESDE RS12315
gene id: 756499:DESDE_RS12315
uniprot id: I4AA82
names: Similarity
messages: Belongs to the asparaginase 1 family.

756499:DESDE RS14740
gene id: 756499:DESDE_RS14740
uniprot id: I4ABK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

756499:DESDE RS05460
gene id: 756499:DESDE_RS05460
uniprot id: I4A6G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

756499:DESDE RS18485
gene id: 756499:DESDE_RS18485
uniprot id: I4ADP0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

756499:DESDE RS07610
gene id: 756499:DESDE_RS07610
uniprot id: I4A7N3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS08875
gene id: 756499:DESDE_RS08875
uniprot id: I4A8C8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19750
gene id: 756499:DESDE_RS19750
uniprot id: I4AED6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

756499:DESDE RS08390
gene id: 756499:DESDE_RS08390
uniprot id: I4A834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS19455
gene id: 756499:DESDE_RS19455
uniprot id: I4AE81
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS17105
gene id: 756499:DESDE_RS17105
uniprot id: I4ACX3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

756499:DESDE RS02155
gene id: 756499:DESDE_RS02155
uniprot id: I4A4M3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS17810
gene id: 756499:DESDE_RS17810
uniprot id: I4ADA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

756499:DESDE RS05675
gene id: 756499:DESDE_RS05675
uniprot id: I4A6L0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS04590
gene id: 756499:DESDE_RS04590
uniprot id: I4A5Z2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS04915
gene id: 756499:DESDE_RS04915
uniprot id: I4A656
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS03895
gene id: 756499:DESDE_RS03895
uniprot id: I4A5L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

756499:DESDE RS01630
gene id: 756499:DESDE_RS01630
uniprot id: I4A4C0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS18610
gene id: 756499:DESDE_RS18610
uniprot id: I4ADR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

756499:DESDE RS09295
gene id: 756499:DESDE_RS09295
uniprot id: I4A8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

756499:DESDE RS09115
gene id: 756499:DESDE_RS09115
uniprot id: I4A8H4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS20345
gene id: 756499:DESDE_RS20345
uniprot id: I4AEQ9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS15955
gene id: 756499:DESDE_RS15955
uniprot id: I4AC94
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

756499:DESDE RS06130
gene id: 756499:DESDE_RS06130
uniprot id: I4A6V3
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

756499:DESDE RS11660
gene id: 756499:DESDE_RS11660
uniprot id: I4A9U8
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

756499:DESDE RS17590
gene id: 756499:DESDE_RS17590
uniprot id: I4AD66
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

756499:DESDE RS03070
gene id: 756499:DESDE_RS03070
uniprot id: I4A546
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS13215
gene id: 756499:DESDE_RS13215
uniprot id: I4AAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

756499:DESDE RS11620
gene id: 756499:DESDE_RS11620
uniprot id: I4A9U0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19480
gene id: 756499:DESDE_RS19480
uniprot id: I4AE86
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

756499:DESDE RS14335
gene id: 756499:DESDE_RS14335
uniprot id: I4ABC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

756499:DESDE RS05480
gene id: 756499:DESDE_RS05480
uniprot id: I4A6H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS17230
gene id: 756499:DESDE_RS17230
uniprot id: I4ACZ7
names: Similarity
messages: Belongs to the bacterial flagellin family.

756499:DESDE RS00025
gene id: 756499:DESDE_RS00025
uniprot id: I4A3H2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

756499:DESDE RS03185
gene id: 756499:DESDE_RS03185
uniprot id: I4A568
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS18900
gene id: 756499:DESDE_RS18900
uniprot id: I4ADX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS19870
gene id: 756499:DESDE_RS19870
uniprot id: I4AEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS03695
gene id: 756499:DESDE_RS03695
uniprot id: I4A5H0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

756499:DESDE RS14735
gene id: 756499:DESDE_RS14735
uniprot id: I4ABK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

756499:DESDE RS12060
gene id: 756499:DESDE_RS12060
uniprot id: I4AA30
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

756499:DESDE RS13075
gene id: 756499:DESDE_RS13075
uniprot id: I4AAM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS09490
gene id: 756499:DESDE_RS09490
uniprot id: I4A8P9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS13585
gene id: 756499:DESDE_RS13585
uniprot id: I4AAX4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS00620
gene id: 756499:DESDE_RS00620
uniprot id: I4A3T5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

756499:DESDE RS17495
gene id: 756499:DESDE_RS17495
uniprot id: I4AD47
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

756499:DESDE RS06155
gene id: 756499:DESDE_RS06155
uniprot id: I4A6V8
names: Similarity
messages: Belongs to the manganese catalase family.

756499:DESDE RS01860
gene id: 756499:DESDE_RS01860
uniprot id: I4A4G7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

756499:DESDE RS19215
gene id: 756499:DESDE_RS19215
uniprot id: I4AE34
names: Similarity
messages: Belongs to the YjdM family.

756499:DESDE RS09400
gene id: 756499:DESDE_RS09400
uniprot id: I4A8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

756499:DESDE RS14805
gene id: 756499:DESDE_RS14805
uniprot id: I4ABL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

756499:DESDE RS17665
gene id: 756499:DESDE_RS17665
uniprot id: I4AD80
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

756499:DESDE RS05695
gene id: 756499:DESDE_RS05695
uniprot id: I4A6L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

756499:DESDE RS17000
gene id: 756499:DESDE_RS17000
uniprot id: I4ACV2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

756499:DESDE RS17205
gene id: 756499:DESDE_RS17205
uniprot id: I4ACZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

756499:DESDE RS16690
gene id: 756499:DESDE_RS16690
uniprot id: I4ACN9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

756499:DESDE RS09735
gene id: 756499:DESDE_RS09735
uniprot id: I4A8V0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS20150
gene id: 756499:DESDE_RS20150
uniprot id: I4AEL8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

756499:DESDE RS01855
gene id: 756499:DESDE_RS01855
uniprot id: I4A4G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

756499:DESDE RS00055
gene id: 756499:DESDE_RS00055
uniprot id: I4A3H6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

756499:DESDE RS10030
gene id: 756499:DESDE_RS10030
uniprot id: I4A907
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

756499:DESDE RS02135
gene id: 756499:DESDE_RS02135
uniprot id: I4A4L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

756499:DESDE RS14330
gene id: 756499:DESDE_RS14330
uniprot id: I4ABC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

756499:DESDE RS04005
gene id: 756499:DESDE_RS04005
uniprot id: I4A5M9
names: Similarity
messages: Belongs to the PemK/MazF family.

756499:DESDE RS04885
gene id: 756499:DESDE_RS04885
uniprot id: I4A650
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS06230
gene id: 756499:DESDE_RS06230
uniprot id: I4A6X4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

756499:DESDE RS04785
gene id: 756499:DESDE_RS04785
uniprot id: I4A630
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS16940
gene id: 756499:DESDE_RS16940
uniprot id: I4ACU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

756499:DESDE RS01995
gene id: 756499:DESDE_RS01995
uniprot id: I4A4J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

756499:DESDE RS15690
gene id: 756499:DESDE_RS15690
uniprot id: I4AC42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS01635
gene id: 756499:DESDE_RS01635
uniprot id: I4A4C1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

756499:DESDE RS11125
gene id: 756499:DESDE_RS11125
uniprot id: I4A9J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

756499:DESDE RS17380
gene id: 756499:DESDE_RS17380
uniprot id: I4AD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS06925
gene id: 756499:DESDE_RS06925
uniprot id: I4A7A7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

756499:DESDE RS09725
gene id: 756499:DESDE_RS09725
uniprot id: I4A8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS11265
gene id: 756499:DESDE_RS11265
uniprot id: I4A9M4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS10720
gene id: 756499:DESDE_RS10720
uniprot id: I4A9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

756499:DESDE RS10105
gene id: 756499:DESDE_RS10105
uniprot id: I4A924
names: Similarity
messages: Belongs to the UPF0047 family.

756499:DESDE RS14160
gene id: 756499:DESDE_RS14160
uniprot id: I4AB90
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS18420
gene id: 756499:DESDE_RS18420
uniprot id: I4ADM7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

756499:DESDE RS15720
gene id: 756499:DESDE_RS15720
uniprot id: I4AC48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

756499:DESDE RS13190
gene id: 756499:DESDE_RS13190
uniprot id: I4AAP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

756499:DESDE RS18175
gene id: 756499:DESDE_RS18175
uniprot id: I4ADI2
names: Similarity
messages: Belongs to the TrpC family.

756499:DESDE RS15150
gene id: 756499:DESDE_RS15150
uniprot id: I4ABT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

756499:DESDE RS10780
gene id: 756499:DESDE_RS10780
uniprot id: I4A9C5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

756499:DESDE RS11725
gene id: 756499:DESDE_RS11725
uniprot id: I4A9W1
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

756499:DESDE RS08795
gene id: 756499:DESDE_RS08795
uniprot id: I4A8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

756499:DESDE RS02010
gene id: 756499:DESDE_RS02010
uniprot id: I4A4J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

756499:DESDE RS06720
gene id: 756499:DESDE_RS06720
uniprot id: I4A768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13310
gene id: 756499:DESDE_RS13310
uniprot id: I4AAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

756499:DESDE RS19435
gene id: 756499:DESDE_RS19435
uniprot id: I4AE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

756499:DESDE RS13335
gene id: 756499:DESDE_RS13335
uniprot id: I4AAS6
names: Similarity
messages: Belongs to the GerABKA family.

756499:DESDE RS10660
gene id: 756499:DESDE_RS10660
uniprot id: I4A999
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

756499:DESDE RS19245
gene id: 756499:DESDE_RS19245
uniprot id: I4AE40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS16625
gene id: 756499:DESDE_RS16625
uniprot id: I4ACM5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

756499:DESDE RS11015
gene id: 756499:DESDE_RS11015
uniprot id: I4A9H2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

756499:DESDE RS12880
gene id: 756499:DESDE_RS12880
uniprot id: I4AAI4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

756499:DESDE RS04705
gene id: 756499:DESDE_RS04705
uniprot id: I4A615
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

756499:DESDE RS10520
gene id: 756499:DESDE_RS10520
uniprot id: I4A971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS11130
gene id: 756499:DESDE_RS11130
uniprot id: I4A9J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

756499:DESDE RS17025
gene id: 756499:DESDE_RS17025
uniprot id: I4ACV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

756499:DESDE RS01940
gene id: 756499:DESDE_RS01940
uniprot id: I4A4I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS10805
gene id: 756499:DESDE_RS10805
uniprot id: I4A9D1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

756499:DESDE RS00610
gene id: 756499:DESDE_RS00610
uniprot id: I4A3T3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

756499:DESDE RS15965
gene id: 756499:DESDE_RS15965
uniprot id: I4AC96
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

756499:DESDE RS01595
gene id: 756499:DESDE_RS01595
uniprot id: I4A4B4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

756499:DESDE RS09510
gene id: 756499:DESDE_RS09510
uniprot id: I4A8Q3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS10870
gene id: 756499:DESDE_RS10870
uniprot id: I4A9E4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

756499:DESDE RS19985
gene id: 756499:DESDE_RS19985
uniprot id: I4AEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

756499:DESDE RS13225
gene id: 756499:DESDE_RS13225
uniprot id: I4AAQ3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

756499:DESDE RS03490
gene id: 756499:DESDE_RS03490
uniprot id: I4A5C9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

756499:DESDE RS08095
gene id: 756499:DESDE_RS08095
uniprot id: I4A7X9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16665
gene id: 756499:DESDE_RS16665
uniprot id: I4ACN4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS14275
gene id: 756499:DESDE_RS14275
uniprot id: I4ABB0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

756499:DESDE RS06420
gene id: 756499:DESDE_RS06420
uniprot id: I4A709
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

756499:DESDE RS03235
gene id: 756499:DESDE_RS03235
uniprot id: I4A578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

756499:DESDE RS11640
gene id: 756499:DESDE_RS11640
uniprot id: I4A9U4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

756499:DESDE RS11605
gene id: 756499:DESDE_RS11605
uniprot id: I4A9T7
names: Similarity
messages: Belongs to the ArsC family.

756499:DESDE RS13700
gene id: 756499:DESDE_RS13700
uniprot id: I4AAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

756499:DESDE RS09495
gene id: 756499:DESDE_RS09495
uniprot id: I4A8Q0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

756499:DESDE RS00005
gene id: 756499:DESDE_RS00005
uniprot id: I4A3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

756499:DESDE RS05680
gene id: 756499:DESDE_RS05680
uniprot id: I4A6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

756499:DESDE RS20090
gene id: 756499:DESDE_RS20090
uniprot id: I4AEK6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13985
gene id: 756499:DESDE_RS13985
uniprot id: I4AB53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

756499:DESDE RS20435
gene id: 756499:DESDE_RS20435
uniprot id: I4AES6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS09110
gene id: 756499:DESDE_RS09110
uniprot id: I4A8H3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS17865
gene id: 756499:DESDE_RS17865
uniprot id: I4ADC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

756499:DESDE RS09470
gene id: 756499:DESDE_RS09470
uniprot id: I4A8P6
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

756499:DESDE RS14405
gene id: 756499:DESDE_RS14405
uniprot id: I4ABD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

756499:DESDE RS08035
gene id: 756499:DESDE_RS08035
uniprot id: I4A7W7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

756499:DESDE RS19150
gene id: 756499:DESDE_RS19150
uniprot id: I4AE21
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

756499:DESDE RS04540
gene id: 756499:DESDE_RS04540
uniprot id: I4A5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

756499:DESDE RS19225
gene id: 756499:DESDE_RS19225
uniprot id: I4AE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS02390
gene id: 756499:DESDE_RS02390
uniprot id: I4A4R4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS18365
gene id: 756499:DESDE_RS18365
uniprot id: I4ADL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

756499:DESDE RS14955
gene id: 756499:DESDE_RS14955
uniprot id: I4ABP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

756499:DESDE RS18135
gene id: 756499:DESDE_RS18135
uniprot id: I4ADH4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS03755
gene id: 756499:DESDE_RS03755
uniprot id: I4A5I3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS07130
gene id: 756499:DESDE_RS07130
uniprot id: I4AAG9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

756499:DESDE RS11445
gene id: 756499:DESDE_RS11445
uniprot id: I4A9Q4
names: Similarity
messages: Belongs to the CvfB family.

756499:DESDE RS00400
gene id: 756499:DESDE_RS00400
uniprot id: I4A3P2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS17650
gene id: 756499:DESDE_RS17650
uniprot id: I4AD77
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

756499:DESDE RS00270
gene id: 756499:DESDE_RS00270
uniprot id: I4A3L7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS10655
gene id: 756499:DESDE_RS10655
uniprot id: I4A998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

756499:DESDE RS06240
gene id: 756499:DESDE_RS06240
uniprot id: I4A6X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

756499:DESDE RS00555
gene id: 756499:DESDE_RS00555
uniprot id: I4A3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

756499:DESDE RS20260
gene id: 756499:DESDE_RS20260
uniprot id: I4AEP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS14415
gene id: 756499:DESDE_RS14415
uniprot id: I4ABD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS06365
gene id: 756499:DESDE_RS06365
uniprot id: I4A6Z8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

756499:DESDE RS14195
gene id: 756499:DESDE_RS14195
uniprot id: I4AB97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS16005
gene id: 756499:DESDE_RS16005
uniprot id: I4ACA4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS15025
gene id: 756499:DESDE_RS15025
uniprot id: I4ABQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

756499:DESDE RS00565
gene id: 756499:DESDE_RS00565
uniprot id: I4A3S5
names: Similarity
messages: Belongs to the UPF0749 family.

756499:DESDE RS20250
gene id: 756499:DESDE_RS20250
uniprot id: I4AEN9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS06470
gene id: 756499:DESDE_RS06470
uniprot id: I4A718
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

756499:DESDE RS00585
gene id: 756499:DESDE_RS00585
uniprot id: I4A3S8
names: Similarity
messages: Belongs to the DHPS family.

756499:DESDE RS19975
gene id: 756499:DESDE_RS19975
uniprot id: I4AEI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

756499:DESDE RS07670
gene id: 756499:DESDE_RS07670
uniprot id: I4A7P4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

756499:DESDE RS09310
gene id: 756499:DESDE_RS09310
uniprot id: I4A8L2
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

756499:DESDE RS03510
gene id: 756499:DESDE_RS03510
uniprot id: I4A5D3
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

756499:DESDE RS14715
gene id: 756499:DESDE_RS14715
uniprot id: I4ABK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

756499:DESDE RS20600
gene id: 756499:DESDE_RS20600
uniprot id: I4AEV7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

756499:DESDE RS05485
gene id: 756499:DESDE_RS05485
uniprot id: I4A6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18785
gene id: 756499:DESDE_RS18785
uniprot id: I4ADU7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

756499:DESDE RS20690
gene id: 756499:DESDE_RS20690
uniprot id: I4AEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

756499:DESDE RS18440
gene id: 756499:DESDE_RS18440
uniprot id: I4ADN1
names: Similarity
messages: Belongs to the UxaA family.

756499:DESDE RS04810
gene id: 756499:DESDE_RS04810
uniprot id: I4A635
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

756499:DESDE RS15680
gene id: 756499:DESDE_RS15680
uniprot id: I4AC40
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

756499:DESDE RS00360
gene id: 756499:DESDE_RS00360
uniprot id: I4A3N5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

756499:DESDE RS09795
gene id: 756499:DESDE_RS09795
uniprot id: I4A8W1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

756499:DESDE RS00895
gene id: 756499:DESDE_RS00895
uniprot id: I4A3Y1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS02125
gene id: 756499:DESDE_RS02125
uniprot id: I4A4L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

756499:DESDE RS17080
gene id: 756499:DESDE_RS17080
uniprot id: I4ACW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS03250
gene id: 756499:DESDE_RS03250
uniprot id: I4A581
names: Similarity
messages: Belongs to the SAICAR synthetase family.

756499:DESDE RS05835
gene id: 756499:DESDE_RS05835
uniprot id: I4A6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS08080
gene id: 756499:DESDE_RS08080
uniprot id: I4A7X6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS03080
gene id: 756499:DESDE_RS03080
uniprot id: I4A548
names: Similarity
messages: Belongs to the peptidase M20A family.

756499:DESDE RS02375
gene id: 756499:DESDE_RS02375
uniprot id: I4A4R1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS12765
gene id: 756499:DESDE_RS12765
uniprot id: I4AAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

756499:DESDE RS15060
gene id: 756499:DESDE_RS15060
uniprot id: I4ABR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

756499:DESDE RS13955
gene id: 756499:DESDE_RS13955
uniprot id: I4AB47
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

756499:DESDE RS15030
gene id: 756499:DESDE_RS15030
uniprot id: I4ABQ9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

756499:DESDE RS03095
gene id: 756499:DESDE_RS03095
uniprot id: I4A551
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

756499:DESDE RS13605
gene id: 756499:DESDE_RS13605
uniprot id: I4AAX8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS14455
gene id: 756499:DESDE_RS14455
uniprot id: I4ABE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS20280
gene id: 756499:DESDE_RS20280
uniprot id: I4AEP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

756499:DESDE RS16180
gene id: 756499:DESDE_RS16180
uniprot id: I4ACE0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16835
gene id: 756499:DESDE_RS16835
uniprot id: I4ACR9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

756499:DESDE RS11900
gene id: 756499:DESDE_RS11900
uniprot id: I4A9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

756499:DESDE RS01935
gene id: 756499:DESDE_RS01935
uniprot id: I4A4I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS09450
gene id: 756499:DESDE_RS09450
uniprot id: I4A8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS19255
gene id: 756499:DESDE_RS19255
uniprot id: I4AE42
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16235
gene id: 756499:DESDE_RS16235
uniprot id: I4ACF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS11085
gene id: 756499:DESDE_RS11085
uniprot id: I4A9I7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

756499:DESDE RS19690
gene id: 756499:DESDE_RS19690
uniprot id: I4AEC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

756499:DESDE RS09380
gene id: 756499:DESDE_RS09380
uniprot id: I4A8M5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03850
gene id: 756499:DESDE_RS03850
uniprot id: I4A5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS11315
gene id: 756499:DESDE_RS11315
uniprot id: I4A9N3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

756499:DESDE RS15020
gene id: 756499:DESDE_RS15020
uniprot id: I4ABQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

756499:DESDE RS02085
gene id: 756499:DESDE_RS02085
uniprot id: I4A4K9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

756499:DESDE RS11255
gene id: 756499:DESDE_RS11255
uniprot id: I4A9M2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

756499:DESDE RS04900
gene id: 756499:DESDE_RS04900
uniprot id: I4A653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

756499:DESDE RS18080
gene id: 756499:DESDE_RS18080
uniprot id: I4ADG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

756499:DESDE RS13260
gene id: 756499:DESDE_RS13260
uniprot id: I4AAR1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

756499:DESDE RS10820
gene id: 756499:DESDE_RS10820
uniprot id: I4A9D4
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS10640
gene id: 756499:DESDE_RS10640
uniprot id: I4A995
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

756499:DESDE RS03560
gene id: 756499:DESDE_RS03560
uniprot id: I4A5E3
names: Function
names: Subunit
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

756499:DESDE RS02260
gene id: 756499:DESDE_RS02260
uniprot id: I4A4P2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS00175
gene id: 756499:DESDE_RS00175
uniprot id: I4A3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

756499:DESDE RS03675
gene id: 756499:DESDE_RS03675
uniprot id: I4A5G6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16980
gene id: 756499:DESDE_RS16980
uniprot id: I4ACU8
names: Similarity
messages: Belongs to the FlgD family.

756499:DESDE RS03630
gene id: 756499:DESDE_RS03630
uniprot id: I4A5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

756499:DESDE RS15865
gene id: 756499:DESDE_RS15865
uniprot id: I4AC76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

756499:DESDE RS00430
gene id: 756499:DESDE_RS00430
uniprot id: I4A3P8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16845
gene id: 756499:DESDE_RS16845
uniprot id: I4ACS1
names: Similarity
messages: Belongs to the peptidase U62 family.

756499:DESDE RS10865
gene id: 756499:DESDE_RS10865
uniprot id: I4A9E3
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

756499:DESDE RS13545
gene id: 756499:DESDE_RS13545
uniprot id: I4AAW6
names: Similarity
messages: Belongs to the Ahb/Nir family.

756499:DESDE RS02980
gene id: 756499:DESDE_RS02980
uniprot id: I4A528
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS04565
gene id: 756499:DESDE_RS04565
uniprot id: I4A5Y7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS14500
gene id: 756499:DESDE_RS14500
uniprot id: I4ABF5
names: Similarity
messages: Belongs to the UPF0297 family.

756499:DESDE RS10270
gene id: 756499:DESDE_RS10270
uniprot id: I4A927
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

756499:DESDE RS10605
gene id: 756499:DESDE_RS10605
uniprot id: I4A988
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

756499:DESDE RS19470
gene id: 756499:DESDE_RS19470
uniprot id: I4AE84
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS06220
gene id: 756499:DESDE_RS06220
uniprot id: I4A6X2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

756499:DESDE RS01050
gene id: 756499:DESDE_RS01050
uniprot id: I4A411
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

756499:DESDE RS17940
gene id: 756499:DESDE_RS17940
uniprot id: I4ADD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS04450
gene id: 756499:DESDE_RS04450
uniprot id: I4A5W4
names: Similarity
messages: Belongs to the asparagine synthetase family.

756499:DESDE RS15765
gene id: 756499:DESDE_RS15765
uniprot id: I4AC56
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

756499:DESDE RS02120
gene id: 756499:DESDE_RS02120
uniprot id: I4A4L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS14890
gene id: 756499:DESDE_RS14890
uniprot id: I4ABN3
names: Similarity
messages: Belongs to the peptidase M16 family.

756499:DESDE RS17300
gene id: 756499:DESDE_RS17300
uniprot id: I4AD11
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS12075
gene id: 756499:DESDE_RS12075
uniprot id: I4AA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13565
gene id: 756499:DESDE_RS13565
uniprot id: I4AAX0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

756499:DESDE RS09375
gene id: 756499:DESDE_RS09375
uniprot id: I4A8M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS18840
gene id: 756499:DESDE_RS18840
uniprot id: I4ADV9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

756499:DESDE RS19855
gene id: 756499:DESDE_RS19855
uniprot id: I4AEF9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS15655
gene id: 756499:DESDE_RS15655
uniprot id: I4AC35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS04980
gene id: 756499:DESDE_RS04980
uniprot id: I4A669
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

756499:DESDE RS20135
gene id: 756499:DESDE_RS20135
uniprot id: I4AEL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS06145
gene id: 756499:DESDE_RS06145
uniprot id: I4A6V6
names: Similarity
messages: Belongs to the glutamine synthetase family.

756499:DESDE RS09535
gene id: 756499:DESDE_RS09535
uniprot id: I4A8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

756499:DESDE RS14460
gene id: 756499:DESDE_RS14460
uniprot id: I4ABE7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

756499:DESDE RS19170
gene id: 756499:DESDE_RS19170
uniprot id: I4AE25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

756499:DESDE RS01700
gene id: 756499:DESDE_RS01700
uniprot id: I4A4D4
names: Similarity
messages: Belongs to the CarB family.

756499:DESDE RS16185
gene id: 756499:DESDE_RS16185
uniprot id: I4ACE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

756499:DESDE RS17920
gene id: 756499:DESDE_RS17920
uniprot id: I4ADD1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16550
gene id: 756499:DESDE_RS16550
uniprot id: I4ACL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

756499:DESDE RS15740
gene id: 756499:DESDE_RS15740
uniprot id: I4AC51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

756499:DESDE RS01360
gene id: 756499:DESDE_RS01360
uniprot id: I4A468
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

756499:DESDE RS12185
gene id: 756499:DESDE_RS12185
uniprot id: I4AA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

756499:DESDE RS18170
gene id: 756499:DESDE_RS18170
uniprot id: I4ADI1
names: Similarity
messages: Belongs to the peptidase S16 family.

756499:DESDE RS15050
gene id: 756499:DESDE_RS15050
uniprot id: I4ABR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

756499:DESDE RS01520
gene id: 756499:DESDE_RS01520
uniprot id: I4A499
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

756499:DESDE RS14620
gene id: 756499:DESDE_RS14620
uniprot id: I4ABI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS07515
gene id: 756499:DESDE_RS07515
uniprot id: I4A7L5
names: Similarity
messages: Belongs to the pirin family.

756499:DESDE RS05855
gene id: 756499:DESDE_RS05855
uniprot id: I4A6P8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16215
gene id: 756499:DESDE_RS16215
uniprot id: I4ACE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

756499:DESDE RS15805
gene id: 756499:DESDE_RS15805
uniprot id: I4AC64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

756499:DESDE RS14525
gene id: 756499:DESDE_RS14525
uniprot id: I4ABG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

756499:DESDE RS14560
gene id: 756499:DESDE_RS14560
uniprot id: I4ABG8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

756499:DESDE RS07780
gene id: 756499:DESDE_RS07780
uniprot id: I4A7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

756499:DESDE RS18995
gene id: 756499:DESDE_RS18995
uniprot id: I4ADZ0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01080
gene id: 756499:DESDE_RS01080
uniprot id: I4A414
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

756499:DESDE RS20420
gene id: 756499:DESDE_RS20420
uniprot id: I4AES3
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-823 that is involved in catalysis.

756499:DESDE RS18895
gene id: 756499:DESDE_RS18895
uniprot id: I4ADX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

756499:DESDE RS07775
gene id: 756499:DESDE_RS07775
uniprot id: I4A7R5
names: Similarity
messages: Belongs to the UPF0251 family.

756499:DESDE RS01960
gene id: 756499:DESDE_RS01960
uniprot id: I4A4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

756499:DESDE RS12510
gene id: 756499:DESDE_RS12510
uniprot id: I4AAC3
names: Similarity
messages: Belongs to the DEAD box helicase family.

756499:DESDE RS17835
gene id: 756499:DESDE_RS17835
uniprot id: I4ADB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

756499:DESDE RS18125
gene id: 756499:DESDE_RS18125
uniprot id: I4ADH2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

756499:DESDE RS09650
gene id: 756499:DESDE_RS09650
uniprot id: I4A8T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS15460
gene id: 756499:DESDE_RS15460
uniprot id: I4ABZ7
names: Similarity
messages: Belongs to the UPF0758 family.

756499:DESDE RS19575
gene id: 756499:DESDE_RS19575
uniprot id: I4AEA5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

756499:DESDE RS02695
gene id: 756499:DESDE_RS02695
uniprot id: I4A4X6
names: Similarity
messages: Belongs to the RutC family.

756499:DESDE RS17040
gene id: 756499:DESDE_RS17040
uniprot id: U3GJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

756499:DESDE RS06920
gene id: 756499:DESDE_RS06920
uniprot id: I4A7A6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS15895
gene id: 756499:DESDE_RS15895
uniprot id: I4AC82
names: Similarity
messages: Belongs to the fabD family.

756499:DESDE RS16010
gene id: 756499:DESDE_RS16010
uniprot id: I4ACA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

756499:DESDE RS09475
gene id: 756499:DESDE_RS09475
uniprot id: I4A8P7
names: Similarity
messages: Belongs to the RutC family.

756499:DESDE RS20535
gene id: 756499:DESDE_RS20535
uniprot id: I4AEU5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS00815
gene id: 756499:DESDE_RS00815
uniprot id: I4A3W4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS00570
gene id: 756499:DESDE_RS00570
uniprot id: I4A3S6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

756499:DESDE RS20455
gene id: 756499:DESDE_RS20455
uniprot id: I4AET0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS19680
gene id: 756499:DESDE_RS19680
uniprot id: I4AEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

756499:DESDE RS17610
gene id: 756499:DESDE_RS17610
uniprot id: I4AD70
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

756499:DESDE RS15930
gene id: 756499:DESDE_RS15930
uniprot id: I4AC89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

756499:DESDE RS17220
gene id: 756499:DESDE_RS17220
uniprot id: I4ACZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

756499:DESDE RS19115
gene id: 756499:DESDE_RS19115
uniprot id: I4AE14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS14270
gene id: 756499:DESDE_RS14270
uniprot id: I4ABA9
names: Similarity
messages: Belongs to the asp23 family.

756499:DESDE RS08040
gene id: 756499:DESDE_RS08040
uniprot id: I4A7W8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS08600
gene id: 756499:DESDE_RS08600
uniprot id: I4A873
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS20170
gene id: 756499:DESDE_RS20170
uniprot id: I4AEM2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

756499:DESDE RS00230
gene id: 756499:DESDE_RS00230
uniprot id: I4A3K9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

756499:DESDE RS17745
gene id: 756499:DESDE_RS17745
uniprot id: I4AD96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

756499:DESDE RS15745
gene id: 756499:DESDE_RS15745
uniprot id: I4AC52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

756499:DESDE RS08800
gene id: 756499:DESDE_RS08800
uniprot id: I4A8B3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS10945
gene id: 756499:DESDE_RS10945
uniprot id: I4A9F9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

756499:DESDE RS03700
gene id: 756499:DESDE_RS03700
uniprot id: I4A5H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

756499:DESDE RS12365
gene id: 756499:DESDE_RS12365
uniprot id: I4AA93
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

756499:DESDE RS20480
gene id: 756499:DESDE_RS20480
uniprot id: I4AET5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

756499:DESDE RS08900
gene id: 756499:DESDE_RS08900
uniprot id: I4A8D3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

756499:DESDE RS05830
gene id: 756499:DESDE_RS05830
uniprot id: I4A6P3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

756499:DESDE RS09560
gene id: 756499:DESDE_RS09560
uniprot id: I4A8R3
names: Similarity
messages: Belongs to the isochorismate synthase family.

756499:DESDE RS05820
gene id: 756499:DESDE_RS05820
uniprot id: I4A6P1
names: Similarity
messages: Belongs to the AOR/FOR family.

756499:DESDE RS16220
gene id: 756499:DESDE_RS16220
uniprot id: I4ACE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

756499:DESDE RS05990
gene id: 756499:DESDE_RS05990
uniprot id: I4A6S4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

756499:DESDE RS09195
gene id: 756499:DESDE_RS09195
uniprot id: I4A8J0
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS11680
gene id: 756499:DESDE_RS11680
uniprot id: I4A9V2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

756499:DESDE RS02045
gene id: 756499:DESDE_RS02045
uniprot id: I4A4K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

756499:DESDE RS19450
gene id: 756499:DESDE_RS19450
uniprot id: I4AE80
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16760
gene id: 756499:DESDE_RS16760
uniprot id: I4ACQ3
names: Similarity
messages: Belongs to the transpeptidase family.

756499:DESDE RS08175
gene id: 756499:DESDE_RS08175
uniprot id: I4A7Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

756499:DESDE RS13275
gene id: 756499:DESDE_RS13275
uniprot id: I4AAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS05720
gene id: 756499:DESDE_RS05720
uniprot id: I4A6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

756499:DESDE RS15875
gene id: 756499:DESDE_RS15875
uniprot id: I4AC78
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

756499:DESDE RS16055
gene id: 756499:DESDE_RS16055
uniprot id: I4ACB4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

756499:DESDE RS12345
gene id: 756499:DESDE_RS12345
uniprot id: I4AA89
names: Similarity
messages: Belongs to the PspA/IM30 family.

756499:DESDE RS01485
gene id: 756499:DESDE_RS01485
uniprot id: I4A492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

756499:DESDE RS08845
gene id: 756499:DESDE_RS08845
uniprot id: I4A8C2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

756499:DESDE RS13625
gene id: 756499:DESDE_RS13625
uniprot id: I4AAY2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

756499:DESDE RS20440
gene id: 756499:DESDE_RS20440
uniprot id: I4AES7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS04815
gene id: 756499:DESDE_RS04815
uniprot id: I4A636
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

756499:DESDE RS02080
gene id: 756499:DESDE_RS02080
uniprot id: I4A4K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

756499:DESDE RS12190
gene id: 756499:DESDE_RS12190
uniprot id: I4AA57
names: Similarity
messages: Belongs to the peptidase C40 family.

756499:DESDE RS02330
gene id: 756499:DESDE_RS02330
uniprot id: I4A4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS16960
gene id: 756499:DESDE_RS16960
uniprot id: I4ACU4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

756499:DESDE RS17140
gene id: 756499:DESDE_RS17140
uniprot id: U3GK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

756499:DESDE RS15090
gene id: 756499:DESDE_RS15090
uniprot id: I4ABS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

756499:DESDE RS20190
gene id: 756499:DESDE_RS20190
uniprot id: I4AEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

756499:DESDE RS10095
gene id: 756499:DESDE_RS10095
uniprot id: I4A922
names: Similarity
messages: Belongs to the peptidase C40 family.

756499:DESDE RS19265
gene id: 756499:DESDE_RS19265
uniprot id: I4AE44
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16075
gene id: 756499:DESDE_RS16075
uniprot id: I4ACB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

756499:DESDE RS10365
gene id: 756499:DESDE_RS10365
uniprot id: I4A939
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS20590
gene id: 756499:DESDE_RS20590
uniprot id: I4AEV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

756499:DESDE RS01625
gene id: 756499:DESDE_RS01625
uniprot id: I4A4B9
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

756499:DESDE RS19110
gene id: 756499:DESDE_RS19110
uniprot id: I4AE13
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

756499:DESDE RS02600
gene id: 756499:DESDE_RS02600
uniprot id: I4A4V6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

756499:DESDE RS09575
gene id: 756499:DESDE_RS09575
uniprot id: I4A8R6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

756499:DESDE RS03265
gene id: 756499:DESDE_RS03265
uniprot id: I4A584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

756499:DESDE RS03285
gene id: 756499:DESDE_RS03285
uniprot id: I4A587
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

756499:DESDE RS15990
gene id: 756499:DESDE_RS15990
uniprot id: I4ACA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

756499:DESDE RS18220
gene id: 756499:DESDE_RS18220
uniprot id: I4ADJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

756499:DESDE RS02565
gene id: 756499:DESDE_RS02565
uniprot id: I4A4U9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

756499:DESDE RS18115
gene id: 756499:DESDE_RS18115
uniprot id: I4ADH0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13725
gene id: 756499:DESDE_RS13725
uniprot id: I4AB00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

756499:DESDE RS05500
gene id: 756499:DESDE_RS05500
uniprot id: I4A6H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13305
gene id: 756499:DESDE_RS13305
uniprot id: I4AAS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13950
gene id: 756499:DESDE_RS13950
uniprot id: I4AB46
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

756499:DESDE RS18935
gene id: 756499:DESDE_RS18935
uniprot id: I4ADX8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

756499:DESDE RS09700
gene id: 756499:DESDE_RS09700
uniprot id: I4A8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

756499:DESDE RS15640
gene id: 756499:DESDE_RS15640
uniprot id: I4AC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS13720
gene id: 756499:DESDE_RS13720
uniprot id: I4AAZ9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16785
gene id: 756499:DESDE_RS16785
uniprot id: I4ACQ8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

756499:DESDE RS11500
gene id: 756499:DESDE_RS11500
uniprot id: I4A9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

756499:DESDE RS16920
gene id: 756499:DESDE_RS16920
uniprot id: I4ACT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

756499:DESDE RS06400
gene id: 756499:DESDE_RS06400
uniprot id: I4A705
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

756499:DESDE RS13350
gene id: 756499:DESDE_RS13350
uniprot id: I4AAS9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

756499:DESDE RS18480
gene id: 756499:DESDE_RS18480
uniprot id: I4ADN9
names: Similarity
messages: Belongs to the peptidase S41A family.

756499:DESDE RS20175
gene id: 756499:DESDE_RS20175
uniprot id: I4AEM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS20675
gene id: 756499:DESDE_RS20675
uniprot id: I4AEX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

756499:DESDE RS12045
gene id: 756499:DESDE_RS12045
uniprot id: I4AA28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS05575
gene id: 756499:DESDE_RS05575
uniprot id: I4A6I9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

756499:DESDE RS01310
gene id: 756499:DESDE_RS01310
uniprot id: I4A457
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10840
gene id: 756499:DESDE_RS10840
uniprot id: I4A9D8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

756499:DESDE RS10940
gene id: 756499:DESDE_RS10940
uniprot id: I4A9F8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19335
gene id: 756499:DESDE_RS19335
uniprot id: I4AE56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS11970
gene id: 756499:DESDE_RS11970
uniprot id: I4AA13
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

756499:DESDE RS00625
gene id: 756499:DESDE_RS00625
uniprot id: I4A3T6
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS13540
gene id: 756499:DESDE_RS13540
uniprot id: I4AAW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS01710
gene id: 756499:DESDE_RS01710
uniprot id: I4A4D7
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

756499:DESDE RS01245
gene id: 756499:DESDE_RS01245
uniprot id: I4A443
names: Similarity
messages: Belongs to the GerABKA family.

756499:DESDE RS16575
gene id: 756499:DESDE_RS16575
uniprot id: I4ACL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

756499:DESDE RS20215
gene id: 756499:DESDE_RS20215
uniprot id: I4AEN1
names: Similarity
messages: Belongs to the FemABX family.

756499:DESDE RS12635
gene id: 756499:DESDE_RS12635
uniprot id: I4AAE8
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

756499:DESDE RS18825
gene id: 756499:DESDE_RS18825
uniprot id: I4ADV6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

756499:DESDE RS13495
gene id: 756499:DESDE_RS13495
uniprot id: I4AAV6
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

756499:DESDE RS04580
gene id: 756499:DESDE_RS04580
uniprot id: I4A5Z0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

756499:DESDE RS04615
gene id: 756499:DESDE_RS04615
uniprot id: I4A5Z7
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

756499:DESDE RS19955
gene id: 756499:DESDE_RS19955
uniprot id: I4AEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

756499:DESDE RS08360
gene id: 756499:DESDE_RS08360
uniprot id: I4A828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS07685
gene id: 756499:DESDE_RS07685
uniprot id: I4A7P7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS02105
gene id: 756499:DESDE_RS02105
uniprot id: I4A4L3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

756499:DESDE RS20615
gene id: 756499:DESDE_RS20615
uniprot id: I4AEW0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03645
gene id: 756499:DESDE_RS03645
uniprot id: I4A5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS11645
gene id: 756499:DESDE_RS11645
uniprot id: I4A9U5
names: Similarity
messages: Belongs to the RNase H family.

756499:DESDE RS06930
gene id: 756499:DESDE_RS06930
uniprot id: I4A7A8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

756499:DESDE RS09305
gene id: 756499:DESDE_RS09305
uniprot id: I4A8L1
names: Similarity
messages: Belongs to the peptidase M29 family.

756499:DESDE RS11175
gene id: 756499:DESDE_RS11175
uniprot id: I4A9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

756499:DESDE RS17825
gene id: 756499:DESDE_RS17825
uniprot id: I4ADB2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS13965
gene id: 756499:DESDE_RS13965
uniprot id: I4AB49
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

756499:DESDE RS14505
gene id: 756499:DESDE_RS14505
uniprot id: I4ABF6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

756499:DESDE RS01125
gene id: 756499:DESDE_RS01125
uniprot id: I4A423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

756499:DESDE RS19015
gene id: 756499:DESDE_RS19015
uniprot id: I4ADZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS02095
gene id: 756499:DESDE_RS02095
uniprot id: I4A4L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

756499:DESDE RS01225
gene id: 756499:DESDE_RS01225
uniprot id: I4A439
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

756499:DESDE RS17595
gene id: 756499:DESDE_RS17595
uniprot id: I4AD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

756499:DESDE RS09565
gene id: 756499:DESDE_RS09565
uniprot id: I4A8R4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

756499:DESDE RS18070
gene id: 756499:DESDE_RS18070
uniprot id: I4ADG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

756499:DESDE RS18925
gene id: 756499:DESDE_RS18925
uniprot id: I4ADX6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

756499:DESDE RS04480
gene id: 756499:DESDE_RS04480
uniprot id: I4A5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

756499:DESDE RS20370
gene id: 756499:DESDE_RS20370
uniprot id: I4AER4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS03545
gene id: 756499:DESDE_RS03545
uniprot id: I4A5E0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS05595
gene id: 756499:DESDE_RS05595
uniprot id: I4A6J3
names: Subunit
messages: Homodimer.

756499:DESDE RS09820
gene id: 756499:DESDE_RS09820
uniprot id: I4A8W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS11565
gene id: 756499:DESDE_RS11565
uniprot id: I4A9S8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

756499:DESDE RS17720
gene id: 756499:DESDE_RS17720
uniprot id: I4AD91
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13355
gene id: 756499:DESDE_RS13355
uniprot id: I4AAT0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

756499:DESDE RS18050
gene id: 756499:DESDE_RS18050
uniprot id: I4ADF7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

756499:DESDE RS03965
gene id: 756499:DESDE_RS03965
uniprot id: I4A5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

756499:DESDE RS18105
gene id: 756499:DESDE_RS18105
uniprot id: I4ADG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

756499:DESDE RS03215
gene id: 756499:DESDE_RS03215
uniprot id: I4A574
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS07570
gene id: 756499:DESDE_RS07570
uniprot id: I4A7M5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS02705
gene id: 756499:DESDE_RS02705
uniprot id: I4A4X8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

756499:DESDE RS18355
gene id: 756499:DESDE_RS18355
uniprot id: I4ADL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

756499:DESDE RS06215
gene id: 756499:DESDE_RS06215
uniprot id: I4A6X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS19805
gene id: 756499:DESDE_RS19805
uniprot id: I4AEE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS06465
gene id: 756499:DESDE_RS06465
uniprot id: I4A717
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

756499:DESDE RS15795
gene id: 756499:DESDE_RS15795
uniprot id: I4AC62
names: Similarity
messages: Belongs to the DtxR/MntR family.

756499:DESDE RS02280
gene id: 756499:DESDE_RS02280
uniprot id: I4A4P6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS18905
gene id: 756499:DESDE_RS18905
uniprot id: I4ADX2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS18075
gene id: 756499:DESDE_RS18075
uniprot id: I4ADG2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

756499:DESDE RS00170
gene id: 756499:DESDE_RS00170
uniprot id: I4A3J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

756499:DESDE RS10850
gene id: 756499:DESDE_RS10850
uniprot id: I4A9E0
names: Similarity
messages: Belongs to the transpeptidase family.

756499:DESDE RS17965
gene id: 756499:DESDE_RS17965
uniprot id: I4ADE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

756499:DESDE RS12530
gene id: 756499:DESDE_RS12530
uniprot id: I4AAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

756499:DESDE RS00630
gene id: 756499:DESDE_RS00630
uniprot id: I4A3T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS17995
gene id: 756499:DESDE_RS17995
uniprot id: I4ADE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS09365
gene id: 756499:DESDE_RS09365
uniprot id: I4A8M2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS06030
gene id: 756499:DESDE_RS06030
uniprot id: I4A6T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

756499:DESDE RS19315
gene id: 756499:DESDE_RS19315
uniprot id: I4AE52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS17215
gene id: 756499:DESDE_RS17215
uniprot id: I4ACZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

756499:DESDE RS09260
gene id: 756499:DESDE_RS09260
uniprot id: I4A8K3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS08635
gene id: 756499:DESDE_RS08635
uniprot id: I4A880
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS14920
gene id: 756499:DESDE_RS14920
uniprot id: I4ABN9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

756499:DESDE RS13705
gene id: 756499:DESDE_RS13705
uniprot id: I4AAZ6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

756499:DESDE RS01270
gene id: 756499:DESDE_RS01270
uniprot id: I4A449
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10040
gene id: 756499:DESDE_RS10040
uniprot id: I4A909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS00380
gene id: 756499:DESDE_RS00380
uniprot id: I4A3N8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

756499:DESDE RS05050
gene id: 756499:DESDE_RS05050
uniprot id: I4A683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

756499:DESDE RS14665
gene id: 756499:DESDE_RS14665
uniprot id: I4ABI9
names: Similarity
messages: Belongs to the RecJ family.

756499:DESDE RS06895
gene id: 756499:DESDE_RS06895
uniprot id: I4A7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS04500
gene id: 756499:DESDE_RS04500
uniprot id: I4A5X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

756499:DESDE RS08540
gene id: 756499:DESDE_RS08540
uniprot id: I4A861
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13125
gene id: 756499:DESDE_RS13125
uniprot id: I4AAN3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

756499:DESDE RS11895
gene id: 756499:DESDE_RS11895
uniprot id: I4A9Z8
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

756499:DESDE RS14490
gene id: 756499:DESDE_RS14490
uniprot id: I4ABF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

756499:DESDE RS03150
gene id: 756499:DESDE_RS03150
uniprot id: I4A561
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19495
gene id: 756499:DESDE_RS19495
uniprot id: I4AE89
names: Similarity
messages: Belongs to the UPF0751 family.

756499:DESDE RS16600
gene id: 756499:DESDE_RS16600
uniprot id: I4ACM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

756499:DESDE RS08575
gene id: 756499:DESDE_RS08575
uniprot id: I4A868
names: Similarity
messages: Belongs to the peptidase S11 family.

756499:DESDE RS11270
gene id: 756499:DESDE_RS11270
uniprot id: I4A9M5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

756499:DESDE RS12890
gene id: 756499:DESDE_RS12890
uniprot id: I4AAI6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

756499:DESDE RS01905
gene id: 756499:DESDE_RS01905
uniprot id: I4A4H6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

756499:DESDE RS09120
gene id: 756499:DESDE_RS09120
uniprot id: I4A8H5
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS00645
gene id: 756499:DESDE_RS00645
uniprot id: I4A3U0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS09265
gene id: 756499:DESDE_RS09265
uniprot id: I4A8K4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS02040
gene id: 756499:DESDE_RS02040
uniprot id: I4A4K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

756499:DESDE RS11155
gene id: 756499:DESDE_RS11155
uniprot id: I4A9K1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS02930
gene id: 756499:DESDE_RS02930
uniprot id: I4A517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

756499:DESDE RS00710
gene id: 756499:DESDE_RS00710
uniprot id: I4A3U8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS14710
gene id: 756499:DESDE_RS14710
uniprot id: I4ABK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

756499:DESDE RS19965
gene id: 756499:DESDE_RS19965
uniprot id: I4AEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

756499:DESDE RS01135
gene id: 756499:DESDE_RS01135
uniprot id: I4A425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

756499:DESDE RS05705
gene id: 756499:DESDE_RS05705
uniprot id: I4A6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

756499:DESDE RS09465
gene id: 756499:DESDE_RS09465
uniprot id: I4A8P5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10575
gene id: 756499:DESDE_RS10575
uniprot id: I4A982
names: Similarity
messages: Belongs to the peptidase C40 family.

756499:DESDE RS20545
gene id: 756499:DESDE_RS20545
uniprot id: I4AEU7
names: Similarity
messages: Belongs to the leucine-binding protein family.

756499:DESDE RS10385
gene id: 756499:DESDE_RS10385
uniprot id: I4A943
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

756499:DESDE RS06795
gene id: 756499:DESDE_RS06795
uniprot id: I4A781
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

756499:DESDE RS14950
gene id: 756499:DESDE_RS14950
uniprot id: I4ABP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

756499:DESDE RS09605
gene id: 756499:DESDE_RS09605
uniprot id: I4A8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

756499:DESDE RS18190
gene id: 756499:DESDE_RS18190
uniprot id: I4ADI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

756499:DESDE RS16740
gene id: 756499:DESDE_RS16740
uniprot id: I4ACP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

756499:DESDE RS13735
gene id: 756499:DESDE_RS13735
uniprot id: I4AB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

756499:DESDE RS10485
gene id: 756499:DESDE_RS10485
uniprot id: I4A964
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

756499:DESDE RS01340
gene id: 756499:DESDE_RS01340
uniprot id: I4A463
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

756499:DESDE RS05925
gene id: 756499:DESDE_RS05925
uniprot id: I4A6R2
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS11860
gene id: 756499:DESDE_RS11860
uniprot id: I4A9Z0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

756499:DESDE RS03225
gene id: 756499:DESDE_RS03225
uniprot id: I4A576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

756499:DESDE RS00305
gene id: 756499:DESDE_RS00305
uniprot id: I4A3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

756499:DESDE RS18155
gene id: 756499:DESDE_RS18155
uniprot id: I4ADH8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10475
gene id: 756499:DESDE_RS10475
uniprot id: I4A962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS03255
gene id: 756499:DESDE_RS03255
uniprot id: I4A582
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

756499:DESDE RS11235
gene id: 756499:DESDE_RS11235
uniprot id: I4A9L8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS16605
gene id: 756499:DESDE_RS16605
uniprot id: I4ACM1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

756499:DESDE RS04755
gene id: 756499:DESDE_RS04755
uniprot id: I4A625
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS18185
gene id: 756499:DESDE_RS18185
uniprot id: I4ADI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS00010
gene id: 756499:DESDE_RS00010
uniprot id: I4A3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

756499:DESDE RS04455
gene id: 756499:DESDE_RS04455
uniprot id: I4A5W5
names: Similarity
messages: Belongs to the glutamine synthetase family.

756499:DESDE RS10730
gene id: 756499:DESDE_RS10730
uniprot id: I4A9B4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

756499:DESDE RS08385
gene id: 756499:DESDE_RS08385
uniprot id: I4A833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS16790
gene id: 756499:DESDE_RS16790
uniprot id: I4ACQ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS13905
gene id: 756499:DESDE_RS13905
uniprot id: I4AB37
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

756499:DESDE RS05655
gene id: 756499:DESDE_RS05655
uniprot id: I4A6K5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

756499:DESDE RS20485
gene id: 756499:DESDE_RS20485
uniprot id: I4AET6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03030
gene id: 756499:DESDE_RS03030
uniprot id: I4A538
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18920
gene id: 756499:DESDE_RS18920
uniprot id: I4ADX5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

756499:DESDE RS16935
gene id: 756499:DESDE_RS16935
uniprot id: I4ACT9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

756499:DESDE RS17070
gene id: 756499:DESDE_RS17070
uniprot id: I4ACW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

756499:DESDE RS00845
gene id: 756499:DESDE_RS00845
uniprot id: I4A3X0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS07800
gene id: 756499:DESDE_RS07800
uniprot id: I4A7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

756499:DESDE RS18505
gene id: 756499:DESDE_RS18505
uniprot id: I4ADP4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS17065
gene id: 756499:DESDE_RS17065
uniprot id: I4ACW5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

756499:DESDE RS18350
gene id: 756499:DESDE_RS18350
uniprot id: I4ADL3
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

756499:DESDE RS08905
gene id: 756499:DESDE_RS08905
uniprot id: I4A8D4
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS14125
gene id: 756499:DESDE_RS14125
uniprot id: I4AB83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

756499:DESDE RS11865
gene id: 756499:DESDE_RS11865
uniprot id: I4A9Z1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

756499:DESDE RS17710
gene id: 756499:DESDE_RS17710
uniprot id: I4AD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

756499:DESDE RS20225
gene id: 756499:DESDE_RS20225
uniprot id: I4AEN3
names: Similarity
messages: Belongs to the RpoE family.

756499:DESDE RS12680
gene id: 756499:DESDE_RS12680
uniprot id: I4AAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13590
gene id: 756499:DESDE_RS13590
uniprot id: I4AAX5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12520
gene id: 756499:DESDE_RS12520
uniprot id: I4AAC5
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

756499:DESDE RS02070
gene id: 756499:DESDE_RS02070
uniprot id: I4A4K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS01235
gene id: 756499:DESDE_RS01235
uniprot id: I4A441
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

756499:DESDE RS17715
gene id: 756499:DESDE_RS17715
uniprot id: I4AD90
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01655
gene id: 756499:DESDE_RS01655
uniprot id: I4A4C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

756499:DESDE RS16685
gene id: 756499:DESDE_RS16685
uniprot id: I4ACN8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS01925
gene id: 756499:DESDE_RS01925
uniprot id: I4A4I0
names: Similarity
messages: Belongs to the ycf81 family.

756499:DESDE RS15750
gene id: 756499:DESDE_RS15750
uniprot id: I4AC53
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

756499:DESDE RS00545
gene id: 756499:DESDE_RS00545
uniprot id: I4A3S1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

756499:DESDE RS00825
gene id: 756499:DESDE_RS00825
uniprot id: I4A3W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

756499:DESDE RS10110
gene id: 756499:DESDE_RS10110
uniprot id: I4A925
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS18005
gene id: 756499:DESDE_RS18005
uniprot id: I4ADE8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

756499:DESDE RS09945
gene id: 756499:DESDE_RS09945
uniprot id: I4A8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

756499:DESDE RS19160
gene id: 756499:DESDE_RS19160
uniprot id: I4AE23
names: Similarity
messages: Belongs to the peptidase M24B family.

756499:DESDE RS16060
gene id: 756499:DESDE_RS16060
uniprot id: I4ACB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

756499:DESDE RS13820
gene id: 756499:DESDE_RS13820
uniprot id: I4AB20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

756499:DESDE RS01600
gene id: 756499:DESDE_RS01600
uniprot id: I4A4B5
names: Similarity
messages: Belongs to the serpin family.

756499:DESDE RS05955
gene id: 756499:DESDE_RS05955
uniprot id: I4A6R8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03015
gene id: 756499:DESDE_RS03015
uniprot id: I4A535
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

756499:DESDE RS07280
gene id: 756499:DESDE_RS07280
uniprot id: I4A7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS10395
gene id: 756499:DESDE_RS10395
uniprot id: I4A945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

756499:DESDE RS06210
gene id: 756499:DESDE_RS06210
uniprot id: I4A6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

756499:DESDE RS03450
gene id: 756499:DESDE_RS03450
uniprot id: I4A5C0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

756499:DESDE RS01145
gene id: 756499:DESDE_RS01145
uniprot id: I4A427
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

756499:DESDE RS01380
gene id: 756499:DESDE_RS01380
uniprot id: I4A472
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS17260
gene id: 756499:DESDE_RS17260
uniprot id: I4AD03
names: Similarity
messages: Belongs to the MotB family.

756499:DESDE RS08755
gene id: 756499:DESDE_RS08755
uniprot id: I4A8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

756499:DESDE RS16070
gene id: 756499:DESDE_RS16070
uniprot id: I4ACB7
names: Similarity
messages: Belongs to the UPF0145 family.

756499:DESDE RS13690
gene id: 756499:DESDE_RS13690
uniprot id: I4AAZ3
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

756499:DESDE RS11985
gene id: 756499:DESDE_RS11985
uniprot id: I4AA16
names: Similarity
messages: Belongs to the Fur family.

756499:DESDE RS12300
gene id: 756499:DESDE_RS12300
uniprot id: I4AA79
names: Similarity
messages: Belongs to the IMPACT family.

756499:DESDE RS08010
gene id: 756499:DESDE_RS08010
uniprot id: I4A7W2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

756499:DESDE RS01265
gene id: 756499:DESDE_RS01265
uniprot id: I4A448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

756499:DESDE RS17830
gene id: 756499:DESDE_RS17830
uniprot id: I4ADB3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS14450
gene id: 756499:DESDE_RS14450
uniprot id: I4ABE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

756499:DESDE RS16950
gene id: 756499:DESDE_RS16950
uniprot id: I4ACU2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

756499:DESDE RS07345
gene id: 756499:DESDE_RS07345
uniprot id: I4A7I6
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS11455
gene id: 756499:DESDE_RS11455
uniprot id: I4A9Q6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10715
gene id: 756499:DESDE_RS10715
uniprot id: I4A9B1
names: Similarity
messages: Belongs to the peptidase A31 family.

756499:DESDE RS14580
gene id: 756499:DESDE_RS14580
uniprot id: I4ABH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS16430
gene id: 756499:DESDE_RS16430
uniprot id: I4ACJ1
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

756499:DESDE RS19445
gene id: 756499:DESDE_RS19445
uniprot id: I4AE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

756499:DESDE RS14370
gene id: 756499:DESDE_RS14370
uniprot id: I4ABC9
names: Similarity
messages: Belongs to the GSP E family.

756499:DESDE RS08680
gene id: 756499:DESDE_RS08680
uniprot id: I4A889
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS11230
gene id: 756499:DESDE_RS11230
uniprot id: I4A9L7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

756499:DESDE RS02585
gene id: 756499:DESDE_RS02585
uniprot id: I4A4V3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS13775
gene id: 756499:DESDE_RS13775
uniprot id: I4AB10
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

756499:DESDE RS03800
gene id: 756499:DESDE_RS03800
uniprot id: I4A5J2
names: Similarity
messages: Belongs to the carbamate kinase family.

756499:DESDE RS04730
gene id: 756499:DESDE_RS04730
uniprot id: I4A620
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

756499:DESDE RS14995
gene id: 756499:DESDE_RS14995
uniprot id: I4ABQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13980
gene id: 756499:DESDE_RS13980
uniprot id: I4AB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

756499:DESDE RS06665
gene id: 756499:DESDE_RS06665
uniprot id: I4A757
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

756499:DESDE RS02050
gene id: 756499:DESDE_RS02050
uniprot id: I4A4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

756499:DESDE RS16745
gene id: 756499:DESDE_RS16745
uniprot id: I4ACQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

756499:DESDE RS12080
gene id: 756499:DESDE_RS12080
uniprot id: I4AA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18510
gene id: 756499:DESDE_RS18510
uniprot id: I4ADP5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

756499:DESDE RS09420
gene id: 756499:DESDE_RS09420
uniprot id: I4A8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

756499:DESDE RS01705
gene id: 756499:DESDE_RS01705
uniprot id: I4A4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS17765
gene id: 756499:DESDE_RS17765
uniprot id: I4ADA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

756499:DESDE RS01735
gene id: 756499:DESDE_RS01735
uniprot id: I4A4E2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS08330
gene id: 756499:DESDE_RS08330
uniprot id: I4A823
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS12125
gene id: 756499:DESDE_RS12125
uniprot id: I4AA43
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

756499:DESDE RS15140
gene id: 756499:DESDE_RS15140
uniprot id: I4ABT1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

756499:DESDE RS14435
gene id: 756499:DESDE_RS14435
uniprot id: I4ABE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

756499:DESDE RS09695
gene id: 756499:DESDE_RS09695
uniprot id: I4A8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

756499:DESDE RS02230
gene id: 756499:DESDE_RS02230
uniprot id: I4A4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS20595
gene id: 756499:DESDE_RS20595
uniprot id: I4AEV6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

756499:DESDE RS15935
gene id: 756499:DESDE_RS15935
uniprot id: I4AC90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS10710
gene id: 756499:DESDE_RS10710
uniprot id: I4A9A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS19230
gene id: 756499:DESDE_RS19230
uniprot id: I4AE37
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

756499:DESDE RS06395
gene id: 756499:DESDE_RS06395
uniprot id: I4A704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

756499:DESDE RS14165
gene id: 756499:DESDE_RS14165
uniprot id: I4AB91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

756499:DESDE RS19950
gene id: 756499:DESDE_RS19950
uniprot id: I4AEH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

756499:DESDE RS08060
gene id: 756499:DESDE_RS08060
uniprot id: I4A7X2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

756499:DESDE RS12550
gene id: 756499:DESDE_RS12550
uniprot id: I4AAD1
names: Similarity
messages: Belongs to the UPF0234 family.

756499:DESDE RS08740
gene id: 756499:DESDE_RS08740
uniprot id: I4A8A1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS11245
gene id: 756499:DESDE_RS11245
uniprot id: I4A9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

756499:DESDE RS11275
gene id: 756499:DESDE_RS11275
uniprot id: I4A9M6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS14520
gene id: 756499:DESDE_RS14520
uniprot id: I4ABF9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

756499:DESDE RS14485
gene id: 756499:DESDE_RS14485
uniprot id: I4ABF2
names: Similarity
messages: Belongs to the UPF0473 family.

756499:DESDE RS13380
gene id: 756499:DESDE_RS13380
uniprot id: I4AAT5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

756499:DESDE RS04920
gene id: 756499:DESDE_RS04920
uniprot id: I4A657
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS20505
gene id: 756499:DESDE_RS20505
uniprot id: I4AEU0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

756499:DESDE RS11430
gene id: 756499:DESDE_RS11430
uniprot id: I4A9Q1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19070
gene id: 756499:DESDE_RS19070
uniprot id: I4AE05
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

756499:DESDE RS10670
gene id: 756499:DESDE_RS10670
uniprot id: I4A9A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

756499:DESDE RS00855
gene id: 756499:DESDE_RS00855
uniprot id: I4A3X2
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS04585
gene id: 756499:DESDE_RS04585
uniprot id: I4A5Z1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS04750
gene id: 756499:DESDE_RS04750
uniprot id: I4A624
names: Similarity
messages: Belongs to the P(II) protein family.

756499:DESDE RS02160
gene id: 756499:DESDE_RS02160
uniprot id: I4A4M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS01965
gene id: 756499:DESDE_RS01965
uniprot id: I4A4I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

756499:DESDE RS06815
gene id: 756499:DESDE_RS06815
uniprot id: I4A785
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

756499:DESDE RS14260
gene id: 756499:DESDE_RS14260
uniprot id: I4ABA7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

756499:DESDE RS18330
gene id: 756499:DESDE_RS18330
uniprot id: I4ADK9
names: Similarity
messages: Belongs to the class-I fumarase family.

756499:DESDE RS06640
gene id: 756499:DESDE_RS06640
uniprot id: I4A752
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

756499:DESDE RS06850
gene id: 756499:DESDE_RS06850
uniprot id: I4A792
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS11065
gene id: 756499:DESDE_RS11065
uniprot id: I4A9I2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

756499:DESDE RS18865
gene id: 756499:DESDE_RS18865
uniprot id: I4ADW3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

756499:DESDE RS01100
gene id: 756499:DESDE_RS01100
uniprot id: I4A418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS17770
gene id: 756499:DESDE_RS17770
uniprot id: I4ADA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

756499:DESDE RS05505
gene id: 756499:DESDE_RS05505
uniprot id: I4A6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS06235
gene id: 756499:DESDE_RS06235
uniprot id: I4A6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

756499:DESDE RS15735
gene id: 756499:DESDE_RS15735
uniprot id: I4AC50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

756499:DESDE RS18665
gene id: 756499:DESDE_RS18665
uniprot id: I4ADS4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

756499:DESDE RS18755
gene id: 756499:DESDE_RS18755
uniprot id: I4ADU1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS06435
gene id: 756499:DESDE_RS06435
uniprot id: I4A711
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

756499:DESDE RS12220
gene id: 756499:DESDE_RS12220
uniprot id: I4AA63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

756499:DESDE RS16970
gene id: 756499:DESDE_RS16970
uniprot id: I4ACU6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

756499:DESDE RS15700
gene id: 756499:DESDE_RS15700
uniprot id: I4AC44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

756499:DESDE RS14915
gene id: 756499:DESDE_RS14915
uniprot id: I4ABN8
names: Similarity
messages: Belongs to the ribF family.

756499:DESDE RS06455
gene id: 756499:DESDE_RS06455
uniprot id: I4A715
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

756499:DESDE RS09580
gene id: 756499:DESDE_RS09580
uniprot id: I4A8R7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

756499:DESDE RS16560
gene id: 756499:DESDE_RS16560
uniprot id: I4ACL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

756499:DESDE RS13050
gene id: 756499:DESDE_RS13050
uniprot id: I4AAL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

756499:DESDE RS07580
gene id: 756499:DESDE_RS07580
uniprot id: I4A7M7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS08230
gene id: 756499:DESDE_RS08230
uniprot id: I4A806
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

756499:DESDE RS06020
gene id: 756499:DESDE_RS06020
uniprot id: I4A6T0
names: Similarity
messages: Belongs to the CobH/CbiC family.

756499:DESDE RS17110
gene id: 756499:DESDE_RS17110
uniprot id: I4ACX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

756499:DESDE RS07730
gene id: 756499:DESDE_RS07730
uniprot id: I4A7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS12545
gene id: 756499:DESDE_RS12545
uniprot id: I4AAD0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

756499:DESDE RS17555
gene id: 756499:DESDE_RS17555
uniprot id: I4AD59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

756499:DESDE RS01355
gene id: 756499:DESDE_RS01355
uniprot id: I4A467
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

756499:DESDE RS14355
gene id: 756499:DESDE_RS14355
uniprot id: I4ABC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

756499:DESDE RS18985
gene id: 756499:DESDE_RS18985
uniprot id: I4ADY8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

756499:DESDE RS16205
gene id: 756499:DESDE_RS16205
uniprot id: I4ACE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

756499:DESDE RS02005
gene id: 756499:DESDE_RS02005
uniprot id: I4A4J3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

756499:DESDE RS12670
gene id: 756499:DESDE_RS12670
uniprot id: I4AAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

756499:DESDE RS12400
gene id: 756499:DESDE_RS12400
uniprot id: I4AAA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

756499:DESDE RS09790
gene id: 756499:DESDE_RS09790
uniprot id: I4A8W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

756499:DESDE RS15890
gene id: 756499:DESDE_RS15890
uniprot id: I4AC81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

756499:DESDE RS01890
gene id: 756499:DESDE_RS01890
uniprot id: I4A4H3
names: Similarity
messages: Belongs to the CtsR family.

756499:DESDE RS12165
gene id: 756499:DESDE_RS12165
uniprot id: I4AA51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS06415
gene id: 756499:DESDE_RS06415
uniprot id: I4A708
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

756499:DESDE RS20430
gene id: 756499:DESDE_RS20430
uniprot id: I4AES5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS17850
gene id: 756499:DESDE_RS17850
uniprot id: I4ADB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

756499:DESDE RS19240
gene id: 756499:DESDE_RS19240
uniprot id: I4AE39
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

756499:DESDE RS01825
gene id: 756499:DESDE_RS01825
uniprot id: I4A4G0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS16640
gene id: 756499:DESDE_RS16640
uniprot id: I4ACM9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

756499:DESDE RS17475
gene id: 756499:DESDE_RS17475
uniprot id: I4AD43
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS03475
gene id: 756499:DESDE_RS03475
uniprot id: I4A5C6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

756499:DESDE RS14845
gene id: 756499:DESDE_RS14845
uniprot id: I4ABM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

756499:DESDE RS14655
gene id: 756499:DESDE_RS14655
uniprot id: I4ABI7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

756499:DESDE RS06135
gene id: 756499:DESDE_RS06135
uniprot id: I4A6V4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12390
gene id: 756499:DESDE_RS12390
uniprot id: I4AA99
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

756499:DESDE RS13390
gene id: 756499:DESDE_RS13390
uniprot id: I4AAT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS02115
gene id: 756499:DESDE_RS02115
uniprot id: I4A4L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

756499:DESDE RS15660
gene id: 756499:DESDE_RS15660
uniprot id: I4AC36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS15470
gene id: 756499:DESDE_RS15470
uniprot id: I4ABZ9
names: Similarity
messages: Belongs to the ParB family.

756499:DESDE RS16555
gene id: 756499:DESDE_RS16555
uniprot id: I4ACL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

756499:DESDE RS15985
gene id: 756499:DESDE_RS15985
uniprot id: I4ACA0
names: Similarity
messages: Belongs to the asp23 family.

756499:DESDE RS09620
gene id: 756499:DESDE_RS09620
uniprot id: I4A8S5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS09155
gene id: 756499:DESDE_RS09155
uniprot id: I4A8I2
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS15770
gene id: 756499:DESDE_RS15770
uniprot id: I4AC57
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

756499:DESDE RS08855
gene id: 756499:DESDE_RS08855
uniprot id: I4A8C4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

756499:DESDE RS14365
gene id: 756499:DESDE_RS14365
uniprot id: I4ABC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS13525
gene id: 756499:DESDE_RS13525
uniprot id: I4AAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

756499:DESDE RS09050
gene id: 756499:DESDE_RS09050
uniprot id: I4A8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS00590
gene id: 756499:DESDE_RS00590
uniprot id: I4A3S9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

756499:DESDE RS17085
gene id: 756499:DESDE_RS17085
uniprot id: I4ACW9
names: Subcellular Location Annotation
messages: Cytoplasm

756499:DESDE RS16050
gene id: 756499:DESDE_RS16050
uniprot id: I4ACB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

756499:DESDE RS04485
gene id: 756499:DESDE_RS04485
uniprot id: I4A5X1
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS18760
gene id: 756499:DESDE_RS18760
uniprot id: I4ADU2
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19705
gene id: 756499:DESDE_RS19705
uniprot id: I4AEC8
names: Similarity
messages: Belongs to the peptidase S41A family.

756499:DESDE RS20570
gene id: 756499:DESDE_RS20570
uniprot id: I4AEV1
names: Similarity
messages: Belongs to the peptidase S16 family.

756499:DESDE RS04820
gene id: 756499:DESDE_RS04820
uniprot id: I4A637
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

756499:DESDE RS13340
gene id: 756499:DESDE_RS13340
uniprot id: I4AAS7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

756499:DESDE RS13880
gene id: 756499:DESDE_RS13880
uniprot id: I4AB32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

756499:DESDE RS11695
gene id: 756499:DESDE_RS11695
uniprot id: I4A9V5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

756499:DESDE RS02100
gene id: 756499:DESDE_RS02100
uniprot id: I4A4L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

756499:DESDE RS00425
gene id: 756499:DESDE_RS00425
uniprot id: I4A3P7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS00980
gene id: 756499:DESDE_RS00980
uniprot id: I4A3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS04270
gene id: 756499:DESDE_RS04270
uniprot id: I4A5S9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

756499:DESDE RS13780
gene id: 756499:DESDE_RS13780
uniprot id: I4AB11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

756499:DESDE RS13615
gene id: 756499:DESDE_RS13615
uniprot id: I4AAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

756499:DESDE RS02405
gene id: 756499:DESDE_RS02405
uniprot id: I4A4R7
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16965
gene id: 756499:DESDE_RS16965
uniprot id: I4ACU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

756499:DESDE RS09330
gene id: 756499:DESDE_RS09330
uniprot id: I4A8L6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13065
gene id: 756499:DESDE_RS13065
uniprot id: I4AAM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

756499:DESDE RS17660
gene id: 756499:DESDE_RS17660
uniprot id: I4AD79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS16405
gene id: 756499:DESDE_RS16405
uniprot id: I4ACI6
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

756499:DESDE RS14780
gene id: 756499:DESDE_RS14780
uniprot id: I4ABL4
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

756499:DESDE RS08765
gene id: 756499:DESDE_RS08765
uniprot id: I4A8A6
names: Similarity
messages: Belongs to the hemerythrin family.

756499:DESDE RS06700
gene id: 756499:DESDE_RS06700
uniprot id: I4A764
names: Similarity
messages: Belongs to the manganese catalase family.

756499:DESDE RS19770
gene id: 756499:DESDE_RS19770
uniprot id: I4AEE0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

756499:DESDE RS05440
gene id: 756499:DESDE_RS05440
uniprot id: I4A6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18045
gene id: 756499:DESDE_RS18045
uniprot id: I4ADF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

756499:DESDE RS15165
gene id: 756499:DESDE_RS15165
uniprot id: I4ABT6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS16925
gene id: 756499:DESDE_RS16925
uniprot id: I4ACT7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

756499:DESDE RS14250
gene id: 756499:DESDE_RS14250
uniprot id: I4ABA5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

756499:DESDE RS19795
gene id: 756499:DESDE_RS19795
uniprot id: I4AEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

756499:DESDE RS15365
gene id: 756499:DESDE_RS15365
uniprot id: I4ABX7
names: Similarity
messages: Belongs to the GSP E family.

756499:DESDE RS16440
gene id: 756499:DESDE_RS16440
uniprot id: I4ACJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

756499:DESDE RS00300
gene id: 756499:DESDE_RS00300
uniprot id: I4A3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

756499:DESDE RS03605
gene id: 756499:DESDE_RS03605
uniprot id: I4A5F2
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

756499:DESDE RS02180
gene id: 756499:DESDE_RS02180
uniprot id: I4A4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

756499:DESDE RS06060
gene id: 756499:DESDE_RS06060
uniprot id: I4A6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS09850
gene id: 756499:DESDE_RS09850
uniprot id: I4A8X1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19835
gene id: 756499:DESDE_RS19835
uniprot id: I4AEF4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

756499:DESDE RS06695
gene id: 756499:DESDE_RS06695
uniprot id: I4A763
names: Similarity
messages: Belongs to the GARS family.

756499:DESDE RS18390
gene id: 756499:DESDE_RS18390
uniprot id: I4ADM1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS17050
gene id: 756499:DESDE_RS17050
uniprot id: U3GKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

756499:DESDE RS13620
gene id: 756499:DESDE_RS13620
uniprot id: I4AAY1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS18280
gene id: 756499:DESDE_RS18280
uniprot id: I4ADJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

756499:DESDE RS14120
gene id: 756499:DESDE_RS14120
uniprot id: I4AB82
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

756499:DESDE RS03135
gene id: 756499:DESDE_RS03135
uniprot id: I4A558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS14855
gene id: 756499:DESDE_RS14855
uniprot id: I4ABM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS02190
gene id: 756499:DESDE_RS02190
uniprot id: I4A4M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

756499:DESDE RS13100
gene id: 756499:DESDE_RS13100
uniprot id: I4AAM8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

756499:DESDE RS10705
gene id: 756499:DESDE_RS10705
uniprot id: I4A9A8
names: Similarity
messages: Belongs to the UPF0342 family.

756499:DESDE RS16415
gene id: 756499:DESDE_RS16415
uniprot id: I4ACI8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

756499:DESDE RS00985
gene id: 756499:DESDE_RS00985
uniprot id: I4A3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS15040
gene id: 756499:DESDE_RS15040
uniprot id: I4ABR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

756499:DESDE RS00940
gene id: 756499:DESDE_RS00940
uniprot id: I4A3Y9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

756499:DESDE RS13285
gene id: 756499:DESDE_RS13285
uniprot id: I4AAR6
names: Similarity
messages: Belongs to the UxaA family.

756499:DESDE RS16975
gene id: 756499:DESDE_RS16975
uniprot id: I4ACU7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

756499:DESDE RS02440
gene id: 756499:DESDE_RS02440
uniprot id: I4A4S4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS14575
gene id: 756499:DESDE_RS14575
uniprot id: I4ABH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS16410
gene id: 756499:DESDE_RS16410
uniprot id: I4ACI7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS17345
gene id: 756499:DESDE_RS17345
uniprot id: I4AD18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

756499:DESDE RS20540
gene id: 756499:DESDE_RS20540
uniprot id: I4AEU6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03480
gene id: 756499:DESDE_RS03480
uniprot id: I4A5C7
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

756499:DESDE RS20205
gene id: 756499:DESDE_RS20205
uniprot id: I4AEM9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS15675
gene id: 756499:DESDE_RS15675
uniprot id: I4AC39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

756499:DESDE RS03115
gene id: 756499:DESDE_RS03115
uniprot id: I4A554
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

756499:DESDE RS02075
gene id: 756499:DESDE_RS02075
uniprot id: I4A4K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

756499:DESDE RS02090
gene id: 756499:DESDE_RS02090
uniprot id: I4A4L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

756499:DESDE RS01850
gene id: 756499:DESDE_RS01850
uniprot id: I4A4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

756499:DESDE RS18500
gene id: 756499:DESDE_RS18500
uniprot id: I4ADP3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

756499:DESDE RS02300
gene id: 756499:DESDE_RS02300
uniprot id: I4A4Q0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS11585
gene id: 756499:DESDE_RS11585
uniprot id: I4A9T3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

756499:DESDE RS00925
gene id: 756499:DESDE_RS00925
uniprot id: I4A3Y7
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03705
gene id: 756499:DESDE_RS03705
uniprot id: I4A5H2
names: Similarity
messages: Belongs to the citrate synthase family.

756499:DESDE RS11145
gene id: 756499:DESDE_RS11145
uniprot id: I4A9J9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS10685
gene id: 756499:DESDE_RS10685
uniprot id: I4A9A4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

756499:DESDE RS00690
gene id: 756499:DESDE_RS00690
uniprot id: I4A3U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

756499:DESDE RS18630
gene id: 756499:DESDE_RS18630
uniprot id: I4ADR7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

756499:DESDE RS02270
gene id: 756499:DESDE_RS02270
uniprot id: I4A4P4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS00395
gene id: 756499:DESDE_RS00395
uniprot id: I4A3P1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

756499:DESDE RS06440
gene id: 756499:DESDE_RS06440
uniprot id: I4A712
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

756499:DESDE RS02195
gene id: 756499:DESDE_RS02195
uniprot id: I4A4N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

756499:DESDE RS13885
gene id: 756499:DESDE_RS13885
uniprot id: I4AB33
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

756499:DESDE RS13595
gene id: 756499:DESDE_RS13595
uniprot id: I4AAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS20605
gene id: 756499:DESDE_RS20605
uniprot id: I4AEV8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

756499:DESDE RS16510
gene id: 756499:DESDE_RS16510
uniprot id: I4ACK5
names: Similarity
messages: Belongs to the UPF0236 family.

756499:DESDE RS17870
gene id: 756499:DESDE_RS17870
uniprot id: I4ADC1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

756499:DESDE RS04905
gene id: 756499:DESDE_RS04905
uniprot id: I4A654
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS00180
gene id: 756499:DESDE_RS00180
uniprot id: I4A3J9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

756499:DESDE RS06055
gene id: 756499:DESDE_RS06055
uniprot id: I4A6T6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS13095
gene id: 756499:DESDE_RS13095
uniprot id: I4AAM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

756499:DESDE RS19145
gene id: 756499:DESDE_RS19145
uniprot id: I4AE20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS19530
gene id: 756499:DESDE_RS19530
uniprot id: I4AE96
names: Similarity
messages: Belongs to the TelA family.

756499:DESDE RS07615
gene id: 756499:DESDE_RS07615
uniprot id: I4A7N4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS06805
gene id: 756499:DESDE_RS06805
uniprot id: I4A783
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

756499:DESDE RS00315
gene id: 756499:DESDE_RS00315
uniprot id: I4A3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS02205
gene id: 756499:DESDE_RS02205
uniprot id: I4A4N2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

756499:DESDE RS14445
gene id: 756499:DESDE_RS14445
uniprot id: I4ABE4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

756499:DESDE RS09105
gene id: 756499:DESDE_RS09105
uniprot id: I4A8H2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

756499:DESDE RS01150
gene id: 756499:DESDE_RS01150
uniprot id: I4A428
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

756499:DESDE RS00715
gene id: 756499:DESDE_RS00715
uniprot id: I4A3U9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS00015
gene id: 756499:DESDE_RS00015
uniprot id: I4A3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

756499:DESDE RS17630
gene id: 756499:DESDE_RS17630
uniprot id: I4AD74
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

756499:DESDE RS12265
gene id: 756499:DESDE_RS12265
uniprot id: I4AA71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

756499:DESDE RS16730
gene id: 756499:DESDE_RS16730
uniprot id: I4ACP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS06960
gene id: 756499:DESDE_RS06960
uniprot id: I4A7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

756499:DESDE RS02235
gene id: 756499:DESDE_RS02235
uniprot id: I4A4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS11025
gene id: 756499:DESDE_RS11025
uniprot id: I4A9H4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

756499:DESDE RS10280
gene id: 756499:DESDE_RS10280
uniprot id: I4A929
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12875
gene id: 756499:DESDE_RS12875
uniprot id: I4AAI3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

756499:DESDE RS19960
gene id: 756499:DESDE_RS19960
uniprot id: I4AEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

756499:DESDE RS14600
gene id: 756499:DESDE_RS14600
uniprot id: I4ABH7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS09715
gene id: 756499:DESDE_RS09715
uniprot id: I4A8U6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS05315
gene id: 756499:DESDE_RS05315
uniprot id: I4A6D8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

756499:DESDE RS13875
gene id: 756499:DESDE_RS13875
uniprot id: I4AB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

756499:DESDE RS18945
gene id: 756499:DESDE_RS18945
uniprot id: I4ADY0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS01210
gene id: 756499:DESDE_RS01210
uniprot id: I4A436
names: Similarity
messages: Belongs to the UPF0246 family.

756499:DESDE RS16210
gene id: 756499:DESDE_RS16210
uniprot id: I4ACE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS05840
gene id: 756499:DESDE_RS05840
uniprot id: I4A6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS06705
gene id: 756499:DESDE_RS06705
uniprot id: I4A765
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS14020
gene id: 756499:DESDE_RS14020
uniprot id: I4AB60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS19580
gene id: 756499:DESDE_RS19580
uniprot id: I4AEA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

756499:DESDE RS03950
gene id: 756499:DESDE_RS03950
uniprot id: I4A5M0
names: Similarity
messages: Belongs to the TPP enzyme family.

756499:DESDE RS17320
gene id: 756499:DESDE_RS17320
uniprot id: I4AD16
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

756499:DESDE RS16820
gene id: 756499:DESDE_RS16820
uniprot id: I4ACR6
names: Similarity
messages: Belongs to the UPF0342 family.

756499:DESDE RS00390
gene id: 756499:DESDE_RS00390
uniprot id: I4A3P0
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

756499:DESDE RS09300
gene id: 756499:DESDE_RS09300
uniprot id: I4A8L0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

756499:DESDE RS17045
gene id: 756499:DESDE_RS17045
uniprot id: U3GKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

756499:DESDE RS18400
gene id: 756499:DESDE_RS18400
uniprot id: I4ADM3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS06800
gene id: 756499:DESDE_RS06800
uniprot id: I4A782
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

756499:DESDE RS09315
gene id: 756499:DESDE_RS09315
uniprot id: I4A8L3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

756499:DESDE RS09435
gene id: 756499:DESDE_RS09435
uniprot id: I4A8N8
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19980
gene id: 756499:DESDE_RS19980
uniprot id: I4AEI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

756499:DESDE RS08665
gene id: 756499:DESDE_RS08665
uniprot id: I4A886
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS12850
gene id: 756499:DESDE_RS12850
uniprot id: I4AAH8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS02640
gene id: 756499:DESDE_RS02640
uniprot id: I4A4W4
names: Similarity
messages: Belongs to the Vsr family.

756499:DESDE RS20265
gene id: 756499:DESDE_RS20265
uniprot id: I4AEP2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

756499:DESDE RS08785
gene id: 756499:DESDE_RS08785
uniprot id: I4A8B0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS20470
gene id: 756499:DESDE_RS20470
uniprot id: I4AET3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS11460
gene id: 756499:DESDE_RS11460
uniprot id: I4A9Q7
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS00415
gene id: 756499:DESDE_RS00415
uniprot id: I4A3P5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

756499:DESDE RS17540
gene id: 756499:DESDE_RS17540
uniprot id: I4AD56
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

756499:DESDE RS00905
gene id: 756499:DESDE_RS00905
uniprot id: I4A3Y3
names: Subcellular Location Annotation
messages: Periplasm

756499:DESDE RS09750
gene id: 756499:DESDE_RS09750
uniprot id: I4A8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

756499:DESDE RS16885
gene id: 756499:DESDE_RS16885
uniprot id: I4ACS9
names: Similarity
messages: Belongs to the MecA family.

756499:DESDE RS02985
gene id: 756499:DESDE_RS02985
uniprot id: I4A529
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

756499:DESDE RS00405
gene id: 756499:DESDE_RS00405
uniprot id: I4A3P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

756499:DESDE RS05170
gene id: 756499:DESDE_RS05170
uniprot id: I4A6B0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

756499:DESDE RS14475
gene id: 756499:DESDE_RS14475
uniprot id: I4ABF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

756499:DESDE RS17470
gene id: 756499:DESDE_RS17470
uniprot id: I4AD42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

756499:DESDE RS16480
gene id: 756499:DESDE_RS16480
uniprot id: I4ACK1
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

756499:DESDE RS20315
gene id: 756499:DESDE_RS20315
uniprot id: I4AEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS14030
gene id: 756499:DESDE_RS14030
uniprot id: I4AB63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

756499:DESDE RS02000
gene id: 756499:DESDE_RS02000
uniprot id: I4A4J2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

756499:DESDE RS18695
gene id: 756499:DESDE_RS18695
uniprot id: I4ADT0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

756499:DESDE RS05055
gene id: 756499:DESDE_RS05055
uniprot id: I4A684
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS02715
gene id: 756499:DESDE_RS02715
uniprot id: I4A4Y0
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS15995
gene id: 756499:DESDE_RS15995
uniprot id: I4ACA2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

756499:DESDE RS14905
gene id: 756499:DESDE_RS14905
uniprot id: I4ABN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

756499:DESDE RS06505
gene id: 756499:DESDE_RS06505
uniprot id: I4A725
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

756499:DESDE RS10895
gene id: 756499:DESDE_RS10895
uniprot id: I4A9E9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

756499:DESDE RS14175
gene id: 756499:DESDE_RS14175
uniprot id: I4AB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

756499:DESDE RS10530
gene id: 756499:DESDE_RS10530
uniprot id: I4A973
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

756499:DESDE RS04460
gene id: 756499:DESDE_RS04460
uniprot id: I4A5W6
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS07700
gene id: 756499:DESDE_RS07700
uniprot id: I4A7Q0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS02170
gene id: 756499:DESDE_RS02170
uniprot id: I4A4M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS03610
gene id: 756499:DESDE_RS03610
uniprot id: I4A5F3
names: Similarity
messages: Belongs to the universal stress protein A family.

756499:DESDE RS10665
gene id: 756499:DESDE_RS10665
uniprot id: I4A9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS07885
gene id: 756499:DESDE_RS07885
uniprot id: I4A7T7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

756499:DESDE RS17315
gene id: 756499:DESDE_RS17315
uniprot id: I4AD14
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

756499:DESDE RS13640
gene id: 756499:DESDE_RS13640
uniprot id: I4AAY5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

756499:DESDE RS15710
gene id: 756499:DESDE_RS15710
uniprot id: I4AC46
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

756499:DESDE RS09730
gene id: 756499:DESDE_RS09730
uniprot id: I4A8U9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

756499:DESDE RS16045
gene id: 756499:DESDE_RS16045
uniprot id: I4ACB2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

756499:DESDE RS02955
gene id: 756499:DESDE_RS02955
uniprot id: I4A522
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

756499:DESDE RS02110
gene id: 756499:DESDE_RS02110
uniprot id: I4A4L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

756499:DESDE RS05890
gene id: 756499:DESDE_RS05890
uniprot id: I4A6Q5
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

756499:DESDE RS17480
gene id: 756499:DESDE_RS17480
uniprot id: I4AD44
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

756499:DESDE RS17115
gene id: 756499:DESDE_RS17115
uniprot id: I4ACX5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

756499:DESDE RS06315
gene id: 756499:DESDE_RS06315
uniprot id: I4A6Y9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS15105
gene id: 756499:DESDE_RS15105
uniprot id: I4ABS4
names: Similarity
messages: Belongs to the DprA/Smf family.

756499:DESDE RS07205
gene id: 756499:DESDE_RS07205
uniprot id: I4A7F8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS18215
gene id: 756499:DESDE_RS18215
uniprot id: I4ADJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

756499:DESDE RS06250
gene id: 756499:DESDE_RS06250
uniprot id: I4A6X8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

756499:DESDE RS01720
gene id: 756499:DESDE_RS01720
uniprot id: I4A4D9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

756499:DESDE RS03120
gene id: 756499:DESDE_RS03120
uniprot id: I4A555
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

756499:DESDE RS19200
gene id: 756499:DESDE_RS19200
uniprot id: I4AE31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS08850
gene id: 756499:DESDE_RS08850
uniprot id: I4A8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18625
gene id: 756499:DESDE_RS18625
uniprot id: I4ADR6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

756499:DESDE RS02885
gene id: 756499:DESDE_RS02885
uniprot id: I4A508
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

756499:DESDE RS17560
gene id: 756499:DESDE_RS17560
uniprot id: I4AD60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

756499:DESDE RS18930
gene id: 756499:DESDE_RS18930
uniprot id: I4ADX7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

756499:DESDE RS14770
gene id: 756499:DESDE_RS14770
uniprot id: I4ABL2
names: Similarity
messages: Belongs to the HypD family.

756499:DESDE RS00355
gene id: 756499:DESDE_RS00355
uniprot id: I4A3N4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

756499:DESDE RS01005
gene id: 756499:DESDE_RS01005
uniprot id: I4A402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS04665
gene id: 756499:DESDE_RS04665
uniprot id: I4A607
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

756499:DESDE RS04660
gene id: 756499:DESDE_RS04660
uniprot id: I4A606
names: Similarity
messages: Belongs to the MEMO1 family.

756499:DESDE RS08565
gene id: 756499:DESDE_RS08565
uniprot id: I4A866
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS06660
gene id: 756499:DESDE_RS06660
uniprot id: I4A756
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

756499:DESDE RS12895
gene id: 756499:DESDE_RS12895
uniprot id: I4AAI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

756499:DESDE RS08015
gene id: 756499:DESDE_RS08015
uniprot id: I4A7W3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS07860
gene id: 756499:DESDE_RS07860
uniprot id: I4A7T2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

756499:DESDE RS19600
gene id: 756499:DESDE_RS19600
uniprot id: I4AEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

756499:DESDE RS17800
gene id: 756499:DESDE_RS17800
uniprot id: I4ADA7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS18285
gene id: 756499:DESDE_RS18285
uniprot id: I4ADK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

756499:DESDE RS12100
gene id: 756499:DESDE_RS12100
uniprot id: I4AA38
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

756499:DESDE RS18980
gene id: 756499:DESDE_RS18980
uniprot id: I4ADY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS05490
gene id: 756499:DESDE_RS05490
uniprot id: I4A6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

756499:DESDE RS13555
gene id: 756499:DESDE_RS13555
uniprot id: I4AAW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

756499:DESDE RS00755
gene id: 756499:DESDE_RS00755
uniprot id: I4A3V9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

756499:DESDE RS18055
gene id: 756499:DESDE_RS18055
uniprot id: I4ADF8
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

756499:DESDE RS07040
gene id: 756499:DESDE_RS07040
uniprot id: I4A7C6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS10775
gene id: 756499:DESDE_RS10775
uniprot id: I4A9C4
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

756499:DESDE RS07185
gene id: 756499:DESDE_RS07185
uniprot id: I4A7F4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

756499:DESDE RS11350
gene id: 756499:DESDE_RS11350
uniprot id: I4A9N7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS17785
gene id: 756499:DESDE_RS17785
uniprot id: I4ADA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

756499:DESDE RS08920
gene id: 756499:DESDE_RS08920
uniprot id: I4A8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS05685
gene id: 756499:DESDE_RS05685
uniprot id: I4A6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS14170
gene id: 756499:DESDE_RS14170
uniprot id: I4AB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

756499:DESDE RS20460
gene id: 756499:DESDE_RS20460
uniprot id: I4AET1
names: Similarity
messages: Belongs to the EamA transporter family.

756499:DESDE RS04865
gene id: 756499:DESDE_RS04865
uniprot id: I4A646
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

756499:DESDE RS14425
gene id: 756499:DESDE_RS14425
uniprot id: I4ABE0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

756499:DESDE RS11870
gene id: 756499:DESDE_RS11870
uniprot id: I4A9Z2
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19095
gene id: 756499:DESDE_RS19095
uniprot id: I4AE10
names: Similarity
messages: Belongs to the CdaR family.

756499:DESDE RS00695
gene id: 756499:DESDE_RS00695
uniprot id: I4A3U4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

756499:DESDE RS20565
gene id: 756499:DESDE_RS20565
uniprot id: I4AEV0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

756499:DESDE RS09800
gene id: 756499:DESDE_RS09800
uniprot id: I4A8W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

756499:DESDE RS01955
gene id: 756499:DESDE_RS01955
uniprot id: I4A4I5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

756499:DESDE RS10555
gene id: 756499:DESDE_RS10555
uniprot id: I4A978
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

756499:DESDE RS02915
gene id: 756499:DESDE_RS02915
uniprot id: I4A514
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

756499:DESDE RS14135
gene id: 756499:DESDE_RS14135
uniprot id: I4AB85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS02130
gene id: 756499:DESDE_RS02130
uniprot id: I4A4L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

756499:DESDE RS06385
gene id: 756499:DESDE_RS06385
uniprot id: I4A702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

756499:DESDE RS14025
gene id: 756499:DESDE_RS14025
uniprot id: I4AB61
names: Similarity
messages: Belongs to the DtxR/MntR family.

756499:DESDE RS19720
gene id: 756499:DESDE_RS19720
uniprot id: I4AED1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

756499:DESDE RS10900
gene id: 756499:DESDE_RS10900
uniprot id: I4A9F0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

756499:DESDE RS05645
gene id: 756499:DESDE_RS05645
uniprot id: I4A6K3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS15960
gene id: 756499:DESDE_RS15960
uniprot id: I4AC95
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

756499:DESDE RS17670
gene id: 756499:DESDE_RS17670
uniprot id: I4AD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

756499:DESDE RS02990
gene id: 756499:DESDE_RS02990
uniprot id: I4A530
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

756499:DESDE RS20195
gene id: 756499:DESDE_RS20195
uniprot id: I4AEM7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

756499:DESDE RS00485
gene id: 756499:DESDE_RS00485
uniprot id: I4A3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

756499:DESDE RS18595
gene id: 756499:DESDE_RS18595
uniprot id: I4ADR0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

756499:DESDE RS19605
gene id: 756499:DESDE_RS19605
uniprot id: I4AEB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

756499:DESDE RS04800
gene id: 756499:DESDE_RS04800
uniprot id: I4A633
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS03945
gene id: 756499:DESDE_RS03945
uniprot id: I4A5L9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

756499:DESDE RS01015
gene id: 756499:DESDE_RS01015
uniprot id: I4A404
names: Similarity
messages: Belongs to the phosphopentomutase family.

756499:DESDE RS19035
gene id: 756499:DESDE_RS19035
uniprot id: I4ADZ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

756499:DESDE RS03130
gene id: 756499:DESDE_RS03130
uniprot id: I4A557
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

756499:DESDE RS13835
gene id: 756499:DESDE_RS13835
uniprot id: I4AB23
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

756499:DESDE RS14930
gene id: 756499:DESDE_RS14930
uniprot id: I4ABP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

756499:DESDE RS16425
gene id: 756499:DESDE_RS16425
uniprot id: I4ACJ0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

756499:DESDE RS02210
gene id: 756499:DESDE_RS02210
uniprot id: I4A4N3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

756499:DESDE RS02580
gene id: 756499:DESDE_RS02580
uniprot id: I4A4V2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

756499:DESDE RS12785
gene id: 756499:DESDE_RS12785
uniprot id: I4AAG9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

756499:DESDE RS15055
gene id: 756499:DESDE_RS15055
uniprot id: I4ABR4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS06975
gene id: 756499:DESDE_RS06975
uniprot id: I4A7B7
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

756499:DESDE RS13135
gene id: 756499:DESDE_RS13135
uniprot id: I4AAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS16545
gene id: 756499:DESDE_RS16545
uniprot id: I4ACL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

756499:DESDE RS00795
gene id: 756499:DESDE_RS00795
uniprot id: I4A3W0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

756499:DESDE RS11885
gene id: 756499:DESDE_RS11885
uniprot id: I4A9Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

756499:DESDE RS15045
gene id: 756499:DESDE_RS15045
uniprot id: I4ABR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

756499:DESDE RS19320
gene id: 756499:DESDE_RS19320
uniprot id: I4AE53
names: Similarity
messages: Belongs to the TPP enzyme family.

756499:DESDE RS03395
gene id: 756499:DESDE_RS03395
uniprot id: I4A5A8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

756499:DESDE RS18130
gene id: 756499:DESDE_RS18130
uniprot id: I4ADH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

756499:DESDE RS14935
gene id: 756499:DESDE_RS14935
uniprot id: I4ABP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

756499:DESDE RS02255
gene id: 756499:DESDE_RS02255
uniprot id: I4A4P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS07465
gene id: 756499:DESDE_RS07465
uniprot id: I4A7K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

756499:DESDE RS06735
gene id: 756499:DESDE_RS06735
uniprot id: I4A771
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

756499:DESDE RS10090
gene id: 756499:DESDE_RS10090
uniprot id: I4A920
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS19935
gene id: 756499:DESDE_RS19935
uniprot id: I4AEH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS14075
gene id: 756499:DESDE_RS14075
uniprot id: I4AB72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS13750
gene id: 756499:DESDE_RS13750
uniprot id: I4AB05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

756499:DESDE RS11370
gene id: 756499:DESDE_RS11370
uniprot id: I4AAG9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

756499:DESDE RS06675
gene id: 756499:DESDE_RS06675
uniprot id: I4A759
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

756499:DESDE RS14110
gene id: 756499:DESDE_RS14110
uniprot id: I4AB80
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS12840
gene id: 756499:DESDE_RS12840
uniprot id: I4AAH7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS19250
gene id: 756499:DESDE_RS19250
uniprot id: I4AE41
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

756499:DESDE RS15885
gene id: 756499:DESDE_RS15885
uniprot id: I4AC80
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

756499:DESDE RS05915
gene id: 756499:DESDE_RS05915
uniprot id: I4A6R0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

756499:DESDE RS04740
gene id: 756499:DESDE_RS04740
uniprot id: I4A622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS16265
gene id: 756499:DESDE_RS16265
uniprot id: I4ACF6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

756499:DESDE RS16635
gene id: 756499:DESDE_RS16635
uniprot id: I4ACM8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

756499:DESDE RS02505
gene id: 756499:DESDE_RS02505
uniprot id: I4A4T7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS14550
gene id: 756499:DESDE_RS14550
uniprot id: I4ABG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

756499:DESDE RS19595
gene id: 756499:DESDE_RS19595
uniprot id: I4AEA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

756499:DESDE RS16660
gene id: 756499:DESDE_RS16660
uniprot id: I4ACN3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS02065
gene id: 756499:DESDE_RS02065
uniprot id: I4A4K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

756499:DESDE RS03625
gene id: 756499:DESDE_RS03625
uniprot id: I4A5F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

756499:DESDE RS15110
gene id: 756499:DESDE_RS15110
uniprot id: I4ABS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

756499:DESDE RS08885
gene id: 756499:DESDE_RS08885
uniprot id: I4A8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

756499:DESDE RS18680
gene id: 756499:DESDE_RS18680
uniprot id: I4ADS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

756499:DESDE RS17170
gene id: 756499:DESDE_RS17170
uniprot id: I4ACY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

756499:DESDE RS03665
gene id: 756499:DESDE_RS03665
uniprot id: I4A5G4
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS00105
gene id: 756499:DESDE_RS00105
uniprot id: I4A3I5
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS13755
gene id: 756499:DESDE_RS13755
uniprot id: I4AB06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

756499:DESDE RS11030
gene id: 756499:DESDE_RS11030
uniprot id: I4A9H5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

756499:DESDE RS08835
gene id: 756499:DESDE_RS08835
uniprot id: I4A8C0
names: Similarity
messages: Belongs to the GerABKA family.

756499:DESDE RS11955
gene id: 756499:DESDE_RS11955
uniprot id: I4AA10
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS10630
gene id: 756499:DESDE_RS10630
uniprot id: I4A993
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

756499:DESDE RS15975
gene id: 756499:DESDE_RS15975
uniprot id: I4AC98
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

756499:DESDE RS17925
gene id: 756499:DESDE_RS17925
uniprot id: I4ADD2
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

756499:DESDE RS15160
gene id: 756499:DESDE_RS15160
uniprot id: I4ABT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

756499:DESDE RS10880
gene id: 756499:DESDE_RS10880
uniprot id: I4A9E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS10700
gene id: 756499:DESDE_RS10700
uniprot id: I4A9A7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

756499:DESDE RS13990
gene id: 756499:DESDE_RS13990
uniprot id: I4AB54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

756499:DESDE RS15350
gene id: 756499:DESDE_RS15350
uniprot id: I4ABX4
names: Similarity
messages: Belongs to the intimin/invasin family.

756499:DESDE RS20635
gene id: 756499:DESDE_RS20635
uniprot id: I4AEW4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

756499:DESDE RS13975
gene id: 756499:DESDE_RS13975
uniprot id: I4AB51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

756499:DESDE RS19625
gene id: 756499:DESDE_RS19625
uniprot id: I4AEB4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

756499:DESDE RS17615
gene id: 756499:DESDE_RS17615
uniprot id: I4AD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

756499:DESDE RS18085
gene id: 756499:DESDE_RS18085
uniprot id: I4ADG4
names: Similarity
messages: Belongs to the UPF0758 family.

756499:DESDE RS19165
gene id: 756499:DESDE_RS19165
uniprot id: I4AE24
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

756499:DESDE RS04875
gene id: 756499:DESDE_RS04875
uniprot id: I4A648
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

756499:DESDE RS16770
gene id: 756499:DESDE_RS16770
uniprot id: I4ACQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

756499:DESDE RS19610
gene id: 756499:DESDE_RS19610
uniprot id: I4AEB1
names: Similarity
messages: Belongs to the sigma-54 factor family.

756499:DESDE RS16065
gene id: 756499:DESDE_RS16065
uniprot id: I4ACB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

756499:DESDE RS18210
gene id: 756499:DESDE_RS18210
uniprot id: I4ADI9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

756499:DESDE RS11240
gene id: 756499:DESDE_RS11240
uniprot id: I4A9L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

756499:DESDE RS15095
gene id: 756499:DESDE_RS15095
uniprot id: I4ABS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

756499:DESDE RS04955
gene id: 756499:DESDE_RS04955
uniprot id: I4A664
names: Similarity
messages: Belongs to the UPF0237 family.

756499:DESDE RS15815
gene id: 756499:DESDE_RS15815
uniprot id: I4AC66
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

756499:DESDE RS09630
gene id: 756499:DESDE_RS09630
uniprot id: I4A8S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

756499:DESDE RS19820
gene id: 756499:DESDE_RS19820
uniprot id: I4AEF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS08265
gene id: 756499:DESDE_RS08265
uniprot id: I4A813
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

756499:DESDE RS01240
gene id: 756499:DESDE_RS01240
uniprot id: I4A442
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

756499:DESDE RS09520
gene id: 756499:DESDE_RS09520
uniprot id: I4A8Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

756499:DESDE RS15670
gene id: 756499:DESDE_RS15670
uniprot id: I4AC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

756499:DESDE RS16985
gene id: 756499:DESDE_RS16985
uniprot id: I4ACU9
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

756499:DESDE RS19765
gene id: 756499:DESDE_RS19765
uniprot id: I4AED9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS09385
gene id: 756499:DESDE_RS09385
uniprot id: I4A8M6
names: Similarity
messages: Belongs to the UPF0173 family.

756499:DESDE RS17020
gene id: 756499:DESDE_RS17020
uniprot id: U3GKZ1
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

756499:DESDE RS15755
gene id: 756499:DESDE_RS15755
uniprot id: I4AC54
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS14010
gene id: 756499:DESDE_RS14010
uniprot id: I4AB58
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

756499:DESDE RS02175
gene id: 756499:DESDE_RS02175
uniprot id: I4A4M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

756499:DESDE RS09005
gene id: 756499:DESDE_RS09005
uniprot id: I4A8F4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

756499:DESDE RS15610
gene id: 756499:DESDE_RS15610
uniprot id: I4AC26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

756499:DESDE RS09415
gene id: 756499:DESDE_RS09415
uniprot id: I4A8N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

756499:DESDE RS19045
gene id: 756499:DESDE_RS19045
uniprot id: I4AE00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

756499:DESDE RS00560
gene id: 756499:DESDE_RS00560
uniprot id: I4A3S4
names: Similarity
messages: Belongs to the UPF0749 family.

756499:DESDE RS20130
gene id: 756499:DESDE_RS20130
uniprot id: I4AEL4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

756499:DESDE RS15725
gene id: 756499:DESDE_RS15725
uniprot id: I4AC49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

756499:DESDE RS01990
gene id: 756499:DESDE_RS01990
uniprot id: I4A4J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

756499:DESDE RS09625
gene id: 756499:DESDE_RS09625
uniprot id: I4A8S6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

756499:DESDE RS17820
gene id: 756499:DESDE_RS17820
uniprot id: I4ADB1
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

756499:DESDE RS03105
gene id: 756499:DESDE_RS03105
uniprot id: I4A552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

756499:DESDE RS07475
gene id: 756499:DESDE_RS07475
uniprot id: I4A7K7
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS04345
gene id: 756499:DESDE_RS04345
uniprot id: I4A5U3
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS09635
gene id: 756499:DESDE_RS09635
uniprot id: I4A8S8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

756499:DESDE RS10450
gene id: 756499:DESDE_RS10450
uniprot id: I4A956
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

756499:DESDE RS10035
gene id: 756499:DESDE_RS10035
uniprot id: I4A908
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

756499:DESDE RS07050
gene id: 756499:DESDE_RS07050
uniprot id: I4A7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

756499:DESDE RS06410
gene id: 756499:DESDE_RS06410
uniprot id: I4A707
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

756499:DESDE RS19485
gene id: 756499:DESDE_RS19485
uniprot id: I4AE87
names: Similarity
messages: Belongs to the terpene synthase family.

756499:DESDE RS10570
gene id: 756499:DESDE_RS10570
uniprot id: I4A981
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

756499:DESDE RS21320
gene id: 756499:DESDE_RS21320
uniprot id: I4AC87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

756499:DESDE RS03440
gene id: 756499:DESDE_RS03440
uniprot id: I4A5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

756499:DESDE RS00320
gene id: 756499:DESDE_RS00320
uniprot id: I4A3M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS17895
gene id: 756499:DESDE_RS17895
uniprot id: I4ADC6
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS03085
gene id: 756499:DESDE_RS03085
uniprot id: I4A549
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

756499:DESDE RS19615
gene id: 756499:DESDE_RS19615
uniprot id: I4AEB2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

756499:DESDE RS13420
gene id: 756499:DESDE_RS13420
uniprot id: I4AAU4
names: Similarity
messages: Belongs to the PspA/IM30 family.

756499:DESDE RS08760
gene id: 756499:DESDE_RS08760
uniprot id: I4A8A5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

756499:DESDE RS06110
gene id: 756499:DESDE_RS06110
uniprot id: I4A6U9
names: Subcellular Location Annotation
messages: Membrane

756499:DESDE RS12535
gene id: 756499:DESDE_RS12535
uniprot id: I4AAC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

756499:DESDE RS03930
gene id: 756499:DESDE_RS03930
uniprot id: I4A5L6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

756499:DESDE RS15065
gene id: 756499:DESDE_RS15065
uniprot id: I4ABR6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

756499:DESDE RS03415
gene id: 756499:DESDE_RS03415
uniprot id: I4A5B2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

756499:DESDE RS02975
gene id: 756499:DESDE_RS02975
uniprot id: I4A527
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

756499:DESDE RS04775
gene id: 756499:DESDE_RS04775
uniprot id: I4A628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

756499:DESDE RS18830
gene id: 756499:DESDE_RS18830
uniprot id: I4ADV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

756499:DESDE RS14140
gene id: 756499:DESDE_RS14140
uniprot id: I4AB86
names: Similarity
messages: Belongs to the TlyA family.

756499:DESDE RS00190
gene id: 756499:DESDE_RS00190
uniprot id: I4A3K1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

756499:DESDE RS20335
gene id: 756499:DESDE_RS20335
uniprot id: I4AEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS06025
gene id: 756499:DESDE_RS06025
uniprot id: I4A6T1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

756499:DESDE RS18165
gene id: 756499:DESDE_RS18165
uniprot id: I4ADI0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

756499:DESDE RS06150
gene id: 756499:DESDE_RS06150
uniprot id: I4A6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

756499:DESDE RS17235
gene id: 756499:DESDE_RS17235
uniprot id: I4ACZ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted