755732:FLUTA RS19775
gene id: 755732:FLUTA_RS19775
uniprot id: F2IHW7
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS10160
gene id: 755732:FLUTA_RS10160
uniprot id: F2IKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

755732:FLUTA RS12070
gene id: 755732:FLUTA_RS12070
uniprot id: F2ICZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

755732:FLUTA RS05605
gene id: 755732:FLUTA_RS05605
uniprot id: F2IAI0
names: Similarity
messages: Belongs to the Skp family.

755732:FLUTA RS11445
gene id: 755732:FLUTA_RS11445
uniprot id: F2IBG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

755732:FLUTA RS20445
gene id: 755732:FLUTA_RS20445
uniprot id: F2IDI3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

755732:FLUTA RS13025
gene id: 755732:FLUTA_RS13025
uniprot id: F2IEN9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

755732:FLUTA RS06725
gene id: 755732:FLUTA_RS06725
uniprot id: F2ICW1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

755732:FLUTA RS04825
gene id: 755732:FLUTA_RS04825
uniprot id: F2IK67
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

755732:FLUTA RS20470
gene id: 755732:FLUTA_RS20470
uniprot id: F2IE97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

755732:FLUTA RS04155
gene id: 755732:FLUTA_RS04155
uniprot id: F2IIX3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS05015
gene id: 755732:FLUTA_RS05015
uniprot id: F2I956
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

755732:FLUTA RS01425
gene id: 755732:FLUTA_RS01425
uniprot id: F2ICR6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

755732:FLUTA RS17925
gene id: 755732:FLUTA_RS17925
uniprot id: F2IDZ3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

755732:FLUTA RS17590
gene id: 755732:FLUTA_RS17590
uniprot id: F2ID75
names: Similarity
messages: Belongs to the nitroreductase family.

755732:FLUTA RS13325
gene id: 755732:FLUTA_RS13325
uniprot id: F2IFE9
names: Similarity
messages: Belongs to the RutC family.

755732:FLUTA RS14690
gene id: 755732:FLUTA_RS14690
uniprot id: F2III5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

755732:FLUTA RS14485
gene id: 755732:FLUTA_RS14485
uniprot id: F2IIE4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS16500
gene id: 755732:FLUTA_RS16500
uniprot id: F2IAU9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS03885
gene id: 755732:FLUTA_RS03885
uniprot id: F2IIR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS17195
gene id: 755732:FLUTA_RS17195
uniprot id: F2ICE1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

755732:FLUTA RS07090
gene id: 755732:FLUTA_RS07090
uniprot id: F2IDN4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

755732:FLUTA RS12380
gene id: 755732:FLUTA_RS12380
uniprot id: F2IDR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS11560
gene id: 755732:FLUTA_RS11560
uniprot id: F2IBI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS07205
gene id: 755732:FLUTA_RS07205
uniprot id: F2IDQ7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

755732:FLUTA RS06610
gene id: 755732:FLUTA_RS06610
uniprot id: F2ICT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

755732:FLUTA RS17860
gene id: 755732:FLUTA_RS17860
uniprot id: F2IDY0
names: Similarity
messages: Belongs to the DapB family.

755732:FLUTA RS19255
gene id: 755732:FLUTA_RS19255
uniprot id: F2IH08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

755732:FLUTA RS07075
gene id: 755732:FLUTA_RS07075
uniprot id: F2IDN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

755732:FLUTA RS17680
gene id: 755732:FLUTA_RS17680
uniprot id: F2ID94
names: Similarity
messages: Belongs to the NodU/CmcH family.

755732:FLUTA RS02620
gene id: 755732:FLUTA_RS02620
uniprot id: F2IFS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

755732:FLUTA RS08325
gene id: 755732:FLUTA_RS08325
uniprot id: F2IGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

755732:FLUTA RS03775
gene id: 755732:FLUTA_RS03775
uniprot id: F2II54
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

755732:FLUTA RS13930
gene id: 755732:FLUTA_RS13930
uniprot id: F2IGX8
names: Similarity
messages: Belongs to the Skp family.

755732:FLUTA RS00870
gene id: 755732:FLUTA_RS00870
uniprot id: F2IBV6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

755732:FLUTA RS00915
gene id: 755732:FLUTA_RS00915
uniprot id: F2IBW5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS04035
gene id: 755732:FLUTA_RS04035
uniprot id: F2IIU9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03975
gene id: 755732:FLUTA_RS03975
uniprot id: F2IIT7
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

755732:FLUTA RS04700
gene id: 755732:FLUTA_RS04700
uniprot id: F2IK39
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

755732:FLUTA RS16425
gene id: 755732:FLUTA_RS16425
uniprot id: F2IA81
names: Similarity
messages: Belongs to the SUI1 family.

755732:FLUTA RS03805
gene id: 755732:FLUTA_RS03805
uniprot id: F2II60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

755732:FLUTA RS09030
gene id: 755732:FLUTA_RS09030
uniprot id: F2II82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

755732:FLUTA RS13850
gene id: 755732:FLUTA_RS13850
uniprot id: F2IGW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

755732:FLUTA RS10515
gene id: 755732:FLUTA_RS10515
uniprot id: F2I9D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

755732:FLUTA RS20715
gene id: 755732:FLUTA_RS20715
uniprot id: F2IGS4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

755732:FLUTA RS00175
gene id: 755732:FLUTA_RS00175
uniprot id: F2IAB2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS10395
gene id: 755732:FLUTA_RS10395
uniprot id: F2I9A6
names: Similarity
messages: Belongs to the SufE family.

755732:FLUTA RS01210
gene id: 755732:FLUTA_RS01210
uniprot id: F2ICM5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

755732:FLUTA RS03925
gene id: 755732:FLUTA_RS03925
uniprot id: F2IIS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

755732:FLUTA RS06270
gene id: 755732:FLUTA_RS06270
uniprot id: F2IC19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

755732:FLUTA RS14660
gene id: 755732:FLUTA_RS14660
uniprot id: F2IIH9
names: Subunit
messages: Homodimer.

755732:FLUTA RS08315
gene id: 755732:FLUTA_RS08315
uniprot id: F2IGN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

755732:FLUTA RS01015
gene id: 755732:FLUTA_RS01015
uniprot id: F2IBY6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

755732:FLUTA RS07470
gene id: 755732:FLUTA_RS07470
uniprot id: F2IEF9
names: Similarity
messages: Belongs to the SCO1/2 family.

755732:FLUTA RS20340
gene id: 755732:FLUTA_RS20340
uniprot id: F2IJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

755732:FLUTA RS07865
gene id: 755732:FLUTA_RS07865
uniprot id: F2IF86
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

755732:FLUTA RS04685
gene id: 755732:FLUTA_RS04685
uniprot id: F2IK36
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

755732:FLUTA RS07820
gene id: 755732:FLUTA_RS07820
uniprot id: F2IF77
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS15340
gene id: 755732:FLUTA_RS15340
uniprot id: F2IJY2
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09850
gene id: 755732:FLUTA_RS09850
uniprot id: F2IJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS06265
gene id: 755732:FLUTA_RS06265
uniprot id: F2IC18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

755732:FLUTA RS17350
gene id: 755732:FLUTA_RS17350
uniprot id: F2ICH3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

755732:FLUTA RS09810
gene id: 755732:FLUTA_RS09810
uniprot id: F2IJQ9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

755732:FLUTA RS07385
gene id: 755732:FLUTA_RS07385
uniprot id: F2IEE2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

755732:FLUTA RS11410
gene id: 755732:FLUTA_RS11410
uniprot id: F2IBF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

755732:FLUTA RS18465
gene id: 755732:FLUTA_RS18465
uniprot id: F2IEU8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS05790
gene id: 755732:FLUTA_RS05790
uniprot id: F2IAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

755732:FLUTA RS13895
gene id: 755732:FLUTA_RS13895
uniprot id: F2IGX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS16435
gene id: 755732:FLUTA_RS16435
uniprot id: F2IA83
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

755732:FLUTA RS18180
gene id: 755732:FLUTA_RS18180
uniprot id: F2IE44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

755732:FLUTA RS14630
gene id: 755732:FLUTA_RS14630
uniprot id: F2IIH3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

755732:FLUTA RS09605
gene id: 755732:FLUTA_RS09605
uniprot id: F2IJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

755732:FLUTA RS08055
gene id: 755732:FLUTA_RS08055
uniprot id: F2IFX7
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

755732:FLUTA RS03820
gene id: 755732:FLUTA_RS03820
uniprot id: F2II63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

755732:FLUTA RS09210
gene id: 755732:FLUTA_RS09210
uniprot id: F2IIB7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

755732:FLUTA RS13170
gene id: 755732:FLUTA_RS13170
uniprot id: F2IFC1
names: Similarity
messages: Belongs to the UPF0310 family.

755732:FLUTA RS17155
gene id: 755732:FLUTA_RS17155
uniprot id: F2IBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

755732:FLUTA RS14720
gene id: 755732:FLUTA_RS14720
uniprot id: F2IIJ1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

755732:FLUTA RS08000
gene id: 755732:FLUTA_RS08000
uniprot id: F2IFW6
names: Similarity
messages: Belongs to the peptidase S41A family.

755732:FLUTA RS00155
gene id: 755732:FLUTA_RS00155
uniprot id: F2IAA8
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

755732:FLUTA RS07290
gene id: 755732:FLUTA_RS07290
uniprot id: F2IEC3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

755732:FLUTA RS11765
gene id: 755732:FLUTA_RS11765
uniprot id: F2IC89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

755732:FLUTA RS03940
gene id: 755732:FLUTA_RS03940
uniprot id: F2IIT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

755732:FLUTA RS02755
gene id: 755732:FLUTA_RS02755
uniprot id: F2IFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

755732:FLUTA RS14730
gene id: 755732:FLUTA_RS14730
uniprot id: F2IJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

755732:FLUTA RS18285
gene id: 755732:FLUTA_RS18285
uniprot id: F2IER2
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

755732:FLUTA RS10615
gene id: 755732:FLUTA_RS10615
uniprot id: F2I9V0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

755732:FLUTA RS18980
gene id: 755732:FLUTA_RS18980
uniprot id: F2IGA2
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS17865
gene id: 755732:FLUTA_RS17865
uniprot id: F2IDY1
names: Similarity
messages: Belongs to the peptidase S26 family.

755732:FLUTA RS00890
gene id: 755732:FLUTA_RS00890
uniprot id: F2IBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

755732:FLUTA RS08090
gene id: 755732:FLUTA_RS08090
uniprot id: F2IFY4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS08900
gene id: 755732:FLUTA_RS08900
uniprot id: F2IHK0
names: Similarity
messages: Belongs to the sigma-54 factor family.

755732:FLUTA RS12550
gene id: 755732:FLUTA_RS12550
uniprot id: F2IDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS03140
gene id: 755732:FLUTA_RS03140
uniprot id: F2IGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

755732:FLUTA RS16885
gene id: 755732:FLUTA_RS16885
uniprot id: F2IBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

755732:FLUTA RS03815
gene id: 755732:FLUTA_RS03815
uniprot id: F2II62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

755732:FLUTA RS02725
gene id: 755732:FLUTA_RS02725
uniprot id: F2IFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

755732:FLUTA RS15710
gene id: 755732:FLUTA_RS15710
uniprot id: F2IKJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

755732:FLUTA RS03780
gene id: 755732:FLUTA_RS03780
uniprot id: F2II55
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

755732:FLUTA RS10600
gene id: 755732:FLUTA_RS10600
uniprot id: F2I9E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

755732:FLUTA RS17180
gene id: 755732:FLUTA_RS17180
uniprot id: F2ICD8
names: Similarity
messages: Belongs to the NusB family.

755732:FLUTA RS05540
gene id: 755732:FLUTA_RS05540
uniprot id: F2IAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

755732:FLUTA RS13685
gene id: 755732:FLUTA_RS13685
uniprot id: F2IG73
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

755732:FLUTA RS02425
gene id: 755732:FLUTA_RS02425
uniprot id: F2IF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

755732:FLUTA RS14680
gene id: 755732:FLUTA_RS14680
uniprot id: F2III3
names: Similarity
messages: Belongs to the peptidase C40 family.

755732:FLUTA RS05665
gene id: 755732:FLUTA_RS05665
uniprot id: F2IAJ2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

755732:FLUTA RS13205
gene id: 755732:FLUTA_RS13205
uniprot id: F2IFC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

755732:FLUTA RS17550
gene id: 755732:FLUTA_RS17550
uniprot id: F2ID68
names: Similarity
messages: Belongs to the peptidase S8 family.

755732:FLUTA RS10150
gene id: 755732:FLUTA_RS10150
uniprot id: F2IKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS08890
gene id: 755732:FLUTA_RS08890
uniprot id: F2IHJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS17565
gene id: 755732:FLUTA_RS17565
uniprot id: F2ID71
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

755732:FLUTA RS03875
gene id: 755732:FLUTA_RS03875
uniprot id: F2IIR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

755732:FLUTA RS04600
gene id: 755732:FLUTA_RS04600
uniprot id: F2IK19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

755732:FLUTA RS15725
gene id: 755732:FLUTA_RS15725
uniprot id: F2IKJ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

755732:FLUTA RS20085
gene id: 755732:FLUTA_RS20085
uniprot id: F2IIM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

755732:FLUTA RS01870
gene id: 755732:FLUTA_RS01870
uniprot id: F2IE63
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS13315
gene id: 755732:FLUTA_RS13315
uniprot id: F2IFE7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

755732:FLUTA RS10220
gene id: 755732:FLUTA_RS10220
uniprot id: F2IKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

755732:FLUTA RS21070
gene id: 755732:FLUTA_RS21070
uniprot id: F2IIL1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS15630
gene id: 755732:FLUTA_RS15630
uniprot id: F2IKH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

755732:FLUTA RS14295
gene id: 755732:FLUTA_RS14295
uniprot id: F2IHQ4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS17445
gene id: 755732:FLUTA_RS17445
uniprot id: F2ICJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

755732:FLUTA RS13620
gene id: 755732:FLUTA_RS13620
uniprot id: F2IG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

755732:FLUTA RS15780
gene id: 755732:FLUTA_RS15780
uniprot id: F2I9F1
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

755732:FLUTA RS05385
gene id: 755732:FLUTA_RS05385
uniprot id: F2I9T1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

755732:FLUTA RS13095
gene id: 755732:FLUTA_RS13095
uniprot id: F2IFA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

755732:FLUTA RS11580
gene id: 755732:FLUTA_RS11580
uniprot id: F2IBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

755732:FLUTA RS11085
gene id: 755732:FLUTA_RS11085
uniprot id: F2IAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

755732:FLUTA RS07580
gene id: 755732:FLUTA_RS07580
uniprot id: F2IF31
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS02450
gene id: 755732:FLUTA_RS02450
uniprot id: F2IF27
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

755732:FLUTA RS03590
gene id: 755732:FLUTA_RS03590
uniprot id: F2II16
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

755732:FLUTA RS13445
gene id: 755732:FLUTA_RS13445
uniprot id: F2IG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

755732:FLUTA RS16390
gene id: 755732:FLUTA_RS16390
uniprot id: F2IA74
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

755732:FLUTA RS18590
gene id: 755732:FLUTA_RS18590
uniprot id: F2IFH6
names: Similarity
messages: Belongs to the Dps family.

755732:FLUTA RS18220
gene id: 755732:FLUTA_RS18220
uniprot id: F2IEP9
names: Similarity
messages: Belongs to the peptidase S41A family.

755732:FLUTA RS16110
gene id: 755732:FLUTA_RS16110
uniprot id: F2I9L4
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.

755732:FLUTA RS04265
gene id: 755732:FLUTA_RS04265
uniprot id: F2IJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

755732:FLUTA RS10825
gene id: 755732:FLUTA_RS10825
uniprot id: F2I9Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

755732:FLUTA RS02605
gene id: 755732:FLUTA_RS02605
uniprot id: F2IFR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS03645
gene id: 755732:FLUTA_RS03645
uniprot id: F2II27
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS12625
gene id: 755732:FLUTA_RS12625
uniprot id: F2IDV8
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS11280
gene id: 755732:FLUTA_RS11280
uniprot id: F2IAT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

755732:FLUTA RS17435
gene id: 755732:FLUTA_RS17435
uniprot id: F2ICJ0
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS02635
gene id: 755732:FLUTA_RS02635
uniprot id: F2IFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

755732:FLUTA RS13440
gene id: 755732:FLUTA_RS13440
uniprot id: F2IG23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS20275
gene id: 755732:FLUTA_RS20275
uniprot id: F2IJC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

755732:FLUTA RS12665
gene id: 755732:FLUTA_RS12665
uniprot id: F2IDW6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS06435
gene id: 755732:FLUTA_RS06435
uniprot id: F2IC52
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

755732:FLUTA RS14530
gene id: 755732:FLUTA_RS14530
uniprot id: F2IIF3
names: Similarity
messages: Belongs to the DinB family.

755732:FLUTA RS04475
gene id: 755732:FLUTA_RS04475
uniprot id: F2IJK5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

755732:FLUTA RS06875
gene id: 755732:FLUTA_RS06875
uniprot id: F2IDJ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS09670
gene id: 755732:FLUTA_RS09670
uniprot id: F2IJN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

755732:FLUTA RS02300
gene id: 755732:FLUTA_RS02300
uniprot id: F2IEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

755732:FLUTA RS15485
gene id: 755732:FLUTA_RS15485
uniprot id: F2IKE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

755732:FLUTA RS04385
gene id: 755732:FLUTA_RS04385
uniprot id: F2IJI7
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS14340
gene id: 755732:FLUTA_RS14340
uniprot id: F2IHR3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS01445
gene id: 755732:FLUTA_RS01445
uniprot id: F2ICS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

755732:FLUTA RS02470
gene id: 755732:FLUTA_RS02470
uniprot id: F2IFN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

755732:FLUTA RS18145
gene id: 755732:FLUTA_RS18145
uniprot id: F2IE37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS19260
gene id: 755732:FLUTA_RS19260
uniprot id: F2IH09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS06765
gene id: 755732:FLUTA_RS06765
uniprot id: F2ICW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

755732:FLUTA RS09505
gene id: 755732:FLUTA_RS09505
uniprot id: F2IJ27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

755732:FLUTA RS13760
gene id: 755732:FLUTA_RS13760
uniprot id: F2IGU4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

755732:FLUTA RS16180
gene id: 755732:FLUTA_RS16180
uniprot id: F2IA33
names: Similarity
messages: Belongs to the nitroreductase family.

755732:FLUTA RS05855
gene id: 755732:FLUTA_RS05855
uniprot id: F2IB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

755732:FLUTA RS07405
gene id: 755732:FLUTA_RS07405
uniprot id: F2IEE6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

755732:FLUTA RS20290
gene id: 755732:FLUTA_RS20290
uniprot id: F2IJD2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

755732:FLUTA RS12785
gene id: 755732:FLUTA_RS12785
uniprot id: F2IEJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

755732:FLUTA RS20360
gene id: 755732:FLUTA_RS20360
uniprot id: F2IJE7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

755732:FLUTA RS06045
gene id: 755732:FLUTA_RS06045
uniprot id: F2IBB3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

755732:FLUTA RS07060
gene id: 755732:FLUTA_RS07060
uniprot id: F2IDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

755732:FLUTA RS10830
gene id: 755732:FLUTA_RS10830
uniprot id: F2I9Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

755732:FLUTA RS10185
gene id: 755732:FLUTA_RS10185
uniprot id: F2IKB9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

755732:FLUTA RS04585
gene id: 755732:FLUTA_RS04585
uniprot id: F2IK16
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

755732:FLUTA RS11540
gene id: 755732:FLUTA_RS11540
uniprot id: F2IBI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell.

755732:FLUTA RS01560
gene id: 755732:FLUTA_RS01560
uniprot id: F2IDE5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

755732:FLUTA RS12790
gene id: 755732:FLUTA_RS12790
uniprot id: F2IEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

755732:FLUTA RS12640
gene id: 755732:FLUTA_RS12640
uniprot id: F2IDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

755732:FLUTA RS07210
gene id: 755732:FLUTA_RS07210
uniprot id: F2IDQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

755732:FLUTA RS20300
gene id: 755732:FLUTA_RS20300
uniprot id: F2IJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

755732:FLUTA RS00505
gene id: 755732:FLUTA_RS00505
uniprot id: F2IB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

755732:FLUTA RS05670
gene id: 755732:FLUTA_RS05670
uniprot id: F2IAJ3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

755732:FLUTA RS15705
gene id: 755732:FLUTA_RS15705
uniprot id: F2IKJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

755732:FLUTA RS15810
gene id: 755732:FLUTA_RS15810
uniprot id: F2I9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

755732:FLUTA RS03840
gene id: 755732:FLUTA_RS03840
uniprot id: F2IIR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

755732:FLUTA RS16075
gene id: 755732:FLUTA_RS16075
uniprot id: F2I9K7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

755732:FLUTA RS12395
gene id: 755732:FLUTA_RS12395
uniprot id: F2IDR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

755732:FLUTA RS17215
gene id: 755732:FLUTA_RS17215
uniprot id: F2ICE6
names: Similarity
messages: Belongs to the peptidase M13 family.

755732:FLUTA RS04255
gene id: 755732:FLUTA_RS04255
uniprot id: F2IJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS18560
gene id: 755732:FLUTA_RS18560
uniprot id: F2IFH0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS21690
gene id: 755732:FLUTA_RS21690
uniprot id: F2IDA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

755732:FLUTA RS07850
gene id: 755732:FLUTA_RS07850
uniprot id: F2IF83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

755732:FLUTA RS04540
gene id: 755732:FLUTA_RS04540
uniprot id: F2IK07
names: Similarity
messages: Belongs to the sterol desaturase family.

755732:FLUTA RS13695
gene id: 755732:FLUTA_RS13695
uniprot id: F2IG76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

755732:FLUTA RS00295
gene id: 755732:FLUTA_RS00295
uniprot id: F2IAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

755732:FLUTA RS16990
gene id: 755732:FLUTA_RS16990
uniprot id: F2IBP4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

755732:FLUTA RS03295
gene id: 755732:FLUTA_RS03295
uniprot id: F2IHA0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

755732:FLUTA RS09925
gene id: 755732:FLUTA_RS09925
uniprot id: F2IJT1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

755732:FLUTA RS15840
gene id: 755732:FLUTA_RS15840
uniprot id: F2I9G3
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

755732:FLUTA RS10365
gene id: 755732:FLUTA_RS10365
uniprot id: F2I9A0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

755732:FLUTA RS09880
gene id: 755732:FLUTA_RS09880
uniprot id: F2IJS2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

755732:FLUTA RS14495
gene id: 755732:FLUTA_RS14495
uniprot id: F2IIE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

755732:FLUTA RS10265
gene id: 755732:FLUTA_RS10265
uniprot id: F2IKD4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS19305
gene id: 755732:FLUTA_RS19305
uniprot id: F2IH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

755732:FLUTA RS10755
gene id: 755732:FLUTA_RS10755
uniprot id: F2I9X8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

755732:FLUTA RS20955
gene id: 755732:FLUTA_RS20955
uniprot id: F2I9F5
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

755732:FLUTA RS12585
gene id: 755732:FLUTA_RS12585
uniprot id: F2IDV0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

755732:FLUTA RS13070
gene id: 755732:FLUTA_RS13070
uniprot id: F2IFA4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS16875
gene id: 755732:FLUTA_RS16875
uniprot id: F2IBM1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

755732:FLUTA RS11325
gene id: 755732:FLUTA_RS11325
uniprot id: F2IAU2
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS15055
gene id: 755732:FLUTA_RS15055
uniprot id: F2IJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

755732:FLUTA RS07720
gene id: 755732:FLUTA_RS07720
uniprot id: F2IF58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

755732:FLUTA RS18635
gene id: 755732:FLUTA_RS18635
uniprot id: F2IFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

755732:FLUTA RS10610
gene id: 755732:FLUTA_RS10610
uniprot id: F2I9F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

755732:FLUTA RS20030
gene id: 755732:FLUTA_RS20030
uniprot id: F2IIL4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS08975
gene id: 755732:FLUTA_RS08975
uniprot id: F2II71
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS10050
gene id: 755732:FLUTA_RS10050
uniprot id: F2IK92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

755732:FLUTA RS17725
gene id: 755732:FLUTA_RS17725
uniprot id: F2IDA4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

755732:FLUTA RS08285
gene id: 755732:FLUTA_RS08285
uniprot id: F2IGM7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

755732:FLUTA RS09830
gene id: 755732:FLUTA_RS09830
uniprot id: F2IJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS18705
gene id: 755732:FLUTA_RS18705
uniprot id: F2IFJ9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS20150
gene id: 755732:FLUTA_RS20150
uniprot id: F2IIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

755732:FLUTA RS18140
gene id: 755732:FLUTA_RS18140
uniprot id: F2IE36
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11000
gene id: 755732:FLUTA_RS11000
uniprot id: F2IA22
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

755732:FLUTA RS10800
gene id: 755732:FLUTA_RS10800
uniprot id: F2I9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

755732:FLUTA RS05250
gene id: 755732:FLUTA_RS05250
uniprot id: F2I9Q4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS15850
gene id: 755732:FLUTA_RS15850
uniprot id: F2I9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

755732:FLUTA RS16655
gene id: 755732:FLUTA_RS16655
uniprot id: F2IAY0
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09900
gene id: 755732:FLUTA_RS09900
uniprot id: F2IJS6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

755732:FLUTA RS00960
gene id: 755732:FLUTA_RS00960
uniprot id: F2IBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS16590
gene id: 755732:FLUTA_RS16590
uniprot id: F2IAW7
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS06905
gene id: 755732:FLUTA_RS06905
uniprot id: F2IDJ7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

755732:FLUTA RS11100
gene id: 755732:FLUTA_RS11100
uniprot id: F2IAP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS12830
gene id: 755732:FLUTA_RS12830
uniprot id: F2IEK1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS13980
gene id: 755732:FLUTA_RS13980
uniprot id: F2IGY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

755732:FLUTA RS00900
gene id: 755732:FLUTA_RS00900
uniprot id: F2IBW2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

755732:FLUTA RS16585
gene id: 755732:FLUTA_RS16585
uniprot id: F2IAW6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

755732:FLUTA RS05660
gene id: 755732:FLUTA_RS05660
uniprot id: F2IAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

755732:FLUTA RS12850
gene id: 755732:FLUTA_RS12850
uniprot id: F2IEK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS04465
gene id: 755732:FLUTA_RS04465
uniprot id: F2IJK3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS17710
gene id: 755732:FLUTA_RS17710
uniprot id: F2IDA1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

755732:FLUTA RS00480
gene id: 755732:FLUTA_RS00480
uniprot id: F2IB24
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

755732:FLUTA RS07740
gene id: 755732:FLUTA_RS07740
uniprot id: F2IF61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS06295
gene id: 755732:FLUTA_RS06295
uniprot id: F2IC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

755732:FLUTA RS19245
gene id: 755732:FLUTA_RS19245
uniprot id: F2IGF3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

755732:FLUTA RS08070
gene id: 755732:FLUTA_RS08070
uniprot id: F2IFY0
names: Similarity
messages: Belongs to the ArsC family.

755732:FLUTA RS11960
gene id: 755732:FLUTA_RS11960
uniprot id: F2ICC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

755732:FLUTA RS13730
gene id: 755732:FLUTA_RS13730
uniprot id: F2IGT8
names: Similarity
messages: Belongs to the citrate synthase family.

755732:FLUTA RS07700
gene id: 755732:FLUTA_RS07700
uniprot id: F2IF54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

755732:FLUTA RS13405
gene id: 755732:FLUTA_RS13405
uniprot id: F2IG16
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

755732:FLUTA RS03075
gene id: 755732:FLUTA_RS03075
uniprot id: F2IGK5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

755732:FLUTA RS03350
gene id: 755732:FLUTA_RS03350
uniprot id: F2IHB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS03255
gene id: 755732:FLUTA_RS03255
uniprot id: F2IH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

755732:FLUTA RS11600
gene id: 755732:FLUTA_RS11600
uniprot id: F2IBJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS03890
gene id: 755732:FLUTA_RS03890
uniprot id: F2IIS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

755732:FLUTA RS11875
gene id: 755732:FLUTA_RS11875
uniprot id: F2ICB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

755732:FLUTA RS02285
gene id: 755732:FLUTA_RS02285
uniprot id: F2IEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

755732:FLUTA RS13615
gene id: 755732:FLUTA_RS13615
uniprot id: F2IG58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS08830
gene id: 755732:FLUTA_RS08830
uniprot id: F2IHI8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS01920
gene id: 755732:FLUTA_RS01920
uniprot id: F2IE73
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11750
gene id: 755732:FLUTA_RS11750
uniprot id: F2IC86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

755732:FLUTA RS20090
gene id: 755732:FLUTA_RS20090
uniprot id: F2IIM7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

755732:FLUTA RS21490
gene id: 755732:FLUTA_RS21490
uniprot id: F2ID86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

755732:FLUTA RS03880
gene id: 755732:FLUTA_RS03880
uniprot id: F2IIR8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

755732:FLUTA RS01980
gene id: 755732:FLUTA_RS01980
uniprot id: F2IE85
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS07345
gene id: 755732:FLUTA_RS07345
uniprot id: F2IED4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

755732:FLUTA RS17850
gene id: 755732:FLUTA_RS17850
uniprot id: F2IDX8
names: Similarity
messages: Belongs to the ParB family.

755732:FLUTA RS06985
gene id: 755732:FLUTA_RS06985
uniprot id: F2IDL3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS05620
gene id: 755732:FLUTA_RS05620
uniprot id: F2IAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS10275
gene id: 755732:FLUTA_RS10275
uniprot id: F2IKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS15130
gene id: 755732:FLUTA_RS15130
uniprot id: F2IJU2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

755732:FLUTA RS02515
gene id: 755732:FLUTA_RS02515
uniprot id: F2IFP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

755732:FLUTA RS05575
gene id: 755732:FLUTA_RS05575
uniprot id: F2IAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

755732:FLUTA RS07915
gene id: 755732:FLUTA_RS07915
uniprot id: F2IF96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

755732:FLUTA RS01170
gene id: 755732:FLUTA_RS01170
uniprot id: F2ICL7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

755732:FLUTA RS10270
gene id: 755732:FLUTA_RS10270
uniprot id: F2IKD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

755732:FLUTA RS04815
gene id: 755732:FLUTA_RS04815
uniprot id: F2IK63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

755732:FLUTA RS08605
gene id: 755732:FLUTA_RS08605
uniprot id: F2IHE2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

755732:FLUTA RS08855
gene id: 755732:FLUTA_RS08855
uniprot id: F2IHJ2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

755732:FLUTA RS13940
gene id: 755732:FLUTA_RS13940
uniprot id: F2IGY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

755732:FLUTA RS09430
gene id: 755732:FLUTA_RS09430
uniprot id: F2IJ12
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS01455
gene id: 755732:FLUTA_RS01455
uniprot id: F2ICS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

755732:FLUTA RS09340
gene id: 755732:FLUTA_RS09340
uniprot id: F2IIZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

755732:FLUTA RS13540
gene id: 755732:FLUTA_RS13540
uniprot id: F2IG42
names: Similarity
messages: Belongs to the CinA family.

755732:FLUTA RS04220
gene id: 755732:FLUTA_RS04220
uniprot id: F2IJF3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

755732:FLUTA RS04170
gene id: 755732:FLUTA_RS04170
uniprot id: F2IIX6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

755732:FLUTA RS08765
gene id: 755732:FLUTA_RS08765
uniprot id: F2IHH5
names: Similarity
messages: Belongs to the Dps family.

755732:FLUTA RS00140
gene id: 755732:FLUTA_RS00140
uniprot id: F2IAA5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

755732:FLUTA RS04215
gene id: 755732:FLUTA_RS04215
uniprot id: F2IJF2
names: Similarity
messages: Belongs to the fabD family.

755732:FLUTA RS00605
gene id: 755732:FLUTA_RS00605
uniprot id: F2IB50
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS18030
gene id: 755732:FLUTA_RS18030
uniprot id: F2IE14
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

755732:FLUTA RS08330
gene id: 755732:FLUTA_RS08330
uniprot id: F2IGN6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

755732:FLUTA RS13390
gene id: 755732:FLUTA_RS13390
uniprot id: F2IFG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS10965
gene id: 755732:FLUTA_RS10965
uniprot id: F2IA15
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

755732:FLUTA RS12160
gene id: 755732:FLUTA_RS12160
uniprot id: F2ID16
names: Similarity
messages: Belongs to the peptidase C40 family.

755732:FLUTA RS03270
gene id: 755732:FLUTA_RS03270
uniprot id: F2IH95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

755732:FLUTA RS04775
gene id: 755732:FLUTA_RS04775
uniprot id: F2IK55
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03530
gene id: 755732:FLUTA_RS03530
uniprot id: F2II04
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

755732:FLUTA RS16570
gene id: 755732:FLUTA_RS16570
uniprot id: F2IAW3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

755732:FLUTA RS14260
gene id: 755732:FLUTA_RS14260
uniprot id: F2IHP7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

755732:FLUTA RS09570
gene id: 755732:FLUTA_RS09570
uniprot id: F2IJ41
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS03760
gene id: 755732:FLUTA_RS03760
uniprot id: F2II51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS08290
gene id: 755732:FLUTA_RS08290
uniprot id: F2IGM8
names: Similarity
messages: Belongs to the PGI/PMI family.

755732:FLUTA RS07665
gene id: 755732:FLUTA_RS07665
uniprot id: F2IF48
names: Similarity
messages: Belongs to the HSP15 family.

755732:FLUTA RS03855
gene id: 755732:FLUTA_RS03855
uniprot id: F2IIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

755732:FLUTA RS11235
gene id: 755732:FLUTA_RS11235
uniprot id: F2IAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

755732:FLUTA RS15435
gene id: 755732:FLUTA_RS15435
uniprot id: F2IK04
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

755732:FLUTA RS05580
gene id: 755732:FLUTA_RS05580
uniprot id: F2IAH6
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

755732:FLUTA RS11680
gene id: 755732:FLUTA_RS11680
uniprot id: F2IC72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

755732:FLUTA RS09460
gene id: 755732:FLUTA_RS09460
uniprot id: F2IJ18
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS12695
gene id: 755732:FLUTA_RS12695
uniprot id: F2IDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

755732:FLUTA RS09515
gene id: 755732:FLUTA_RS09515
uniprot id: F2IJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

755732:FLUTA RS06805
gene id: 755732:FLUTA_RS06805
uniprot id: F2ICX5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS10750
gene id: 755732:FLUTA_RS10750
uniprot id: F2I9X7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

755732:FLUTA RS13510
gene id: 755732:FLUTA_RS13510
uniprot id: F2IG36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS10955
gene id: 755732:FLUTA_RS10955
uniprot id: F2IA13
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

755732:FLUTA RS16975
gene id: 755732:FLUTA_RS16975
uniprot id: F2IBP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS15790
gene id: 755732:FLUTA_RS15790
uniprot id: F2I9F3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS07920
gene id: 755732:FLUTA_RS07920
uniprot id: F2IF97
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS03870
gene id: 755732:FLUTA_RS03870
uniprot id: F2IIR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

755732:FLUTA RS17260
gene id: 755732:FLUTA_RS17260
uniprot id: F2ICF5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

755732:FLUTA RS01410
gene id: 755732:FLUTA_RS01410
uniprot id: F2ICR3
names: Subcellular Location Annotation
messages: Periplasm

755732:FLUTA RS00210
gene id: 755732:FLUTA_RS00210
uniprot id: F2IAB9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

755732:FLUTA RS06275
gene id: 755732:FLUTA_RS06275
uniprot id: F2IC20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

755732:FLUTA RS12760
gene id: 755732:FLUTA_RS12760
uniprot id: F2IEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

755732:FLUTA RS05800
gene id: 755732:FLUTA_RS05800
uniprot id: F2IAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

755732:FLUTA RS17780
gene id: 755732:FLUTA_RS17780
uniprot id: F2IDB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

755732:FLUTA RS10290
gene id: 755732:FLUTA_RS10290
uniprot id: F2I985
names: Similarity
messages: Belongs to the peptidase S13 family.

755732:FLUTA RS18765
gene id: 755732:FLUTA_RS18765
uniprot id: F2IFL0
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS14270
gene id: 755732:FLUTA_RS14270
uniprot id: F2IHP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

755732:FLUTA RS08955
gene id: 755732:FLUTA_RS08955
uniprot id: F2II67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS18280
gene id: 755732:FLUTA_RS18280
uniprot id: F2IER1
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

755732:FLUTA RS11595
gene id: 755732:FLUTA_RS11595
uniprot id: F2IBJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

755732:FLUTA RS16105
gene id: 755732:FLUTA_RS16105
uniprot id: F2I9L3
names: Similarity
messages: Belongs to the squalene monooxygenase family.

755732:FLUTA RS03370
gene id: 755732:FLUTA_RS03370
uniprot id: F2IHB5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

755732:FLUTA RS00855
gene id: 755732:FLUTA_RS00855
uniprot id: F2IBV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

755732:FLUTA RS10925
gene id: 755732:FLUTA_RS10925
uniprot id: F2IA07
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS19870
gene id: 755732:FLUTA_RS19870
uniprot id: F2IHY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

755732:FLUTA RS11300
gene id: 755732:FLUTA_RS11300
uniprot id: F2IAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

755732:FLUTA RS12530
gene id: 755732:FLUTA_RS12530
uniprot id: F2IDT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

755732:FLUTA RS17730
gene id: 755732:FLUTA_RS17730
uniprot id: F2IDA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS17715
gene id: 755732:FLUTA_RS17715
uniprot id: F2IDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

755732:FLUTA RS17950
gene id: 755732:FLUTA_RS17950
uniprot id: F2IDZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

755732:FLUTA RS13945
gene id: 755732:FLUTA_RS13945
uniprot id: F2IGY1
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS01975
gene id: 755732:FLUTA_RS01975
uniprot id: F2IE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS12610
gene id: 755732:FLUTA_RS12610
uniprot id: F2IDV5
names: Similarity
messages: Belongs to the peptidase S49 family.

755732:FLUTA RS02645
gene id: 755732:FLUTA_RS02645
uniprot id: F2IFS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

755732:FLUTA RS16410
gene id: 755732:FLUTA_RS16410
uniprot id: F2IA78
names: Similarity
messages: Belongs to the histone deacetylase family.

755732:FLUTA RS20160
gene id: 755732:FLUTA_RS20160
uniprot id: F2IIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

755732:FLUTA RS11080
gene id: 755732:FLUTA_RS11080
uniprot id: F2IAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS21190
gene id: 755732:FLUTA_RS21190
uniprot id: F2IHM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

755732:FLUTA RS04635
gene id: 755732:FLUTA_RS04635
uniprot id: F2IK26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

755732:FLUTA RS04160
gene id: 755732:FLUTA_RS04160
uniprot id: F2IIX4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS02430
gene id: 755732:FLUTA_RS02430
uniprot id: F2IF23
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

755732:FLUTA RS09825
gene id: 755732:FLUTA_RS09825
uniprot id: F2IJR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS07185
gene id: 755732:FLUTA_RS07185
uniprot id: F2IDQ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

755732:FLUTA RS21810
gene id: 755732:FLUTA_RS21810
uniprot id: F2IAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

755732:FLUTA RS07885
gene id: 755732:FLUTA_RS07885
uniprot id: F2IF90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

755732:FLUTA RS00670
gene id: 755732:FLUTA_RS00670
uniprot id: F2IB63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS19930
gene id: 755732:FLUTA_RS19930
uniprot id: F2IIJ6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

755732:FLUTA RS05900
gene id: 755732:FLUTA_RS05900
uniprot id: F2IB85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

755732:FLUTA RS08950
gene id: 755732:FLUTA_RS08950
uniprot id: F2II66
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

755732:FLUTA RS17510
gene id: 755732:FLUTA_RS17510
uniprot id: F2ID60
names: Similarity
messages: Belongs to the CvfB family.

755732:FLUTA RS13555
gene id: 755732:FLUTA_RS13555
uniprot id: F2IG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

755732:FLUTA RS18125
gene id: 755732:FLUTA_RS18125
uniprot id: F2IE33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS02290
gene id: 755732:FLUTA_RS02290
uniprot id: F2IEZ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS11840
gene id: 755732:FLUTA_RS11840
uniprot id: F2ICA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

755732:FLUTA RS18315
gene id: 755732:FLUTA_RS18315
uniprot id: F2IER9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

755732:FLUTA RS04260
gene id: 755732:FLUTA_RS04260
uniprot id: F2IJG0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

755732:FLUTA RS05300
gene id: 755732:FLUTA_RS05300
uniprot id: F2I9R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS20355
gene id: 755732:FLUTA_RS20355
uniprot id: F2IJE6
names: Similarity
messages: Belongs to the arginase family.

755732:FLUTA RS05995
gene id: 755732:FLUTA_RS05995
uniprot id: F2IBA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

755732:FLUTA RS02825
gene id: 755732:FLUTA_RS02825
uniprot id: F2IGF8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

755732:FLUTA RS04370
gene id: 755732:FLUTA_RS04370
uniprot id: F2IJI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS19470
gene id: 755732:FLUTA_RS19470
uniprot id: F2IH51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS01200
gene id: 755732:FLUTA_RS01200
uniprot id: F2ICM3
names: PTM
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

755732:FLUTA RS17650
gene id: 755732:FLUTA_RS17650
uniprot id: F2ID88
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS17770
gene id: 755732:FLUTA_RS17770
uniprot id: F2IDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

755732:FLUTA RS05600
gene id: 755732:FLUTA_RS05600
uniprot id: F2IAH9
names: Similarity
messages: Belongs to the Skp family.

755732:FLUTA RS02685
gene id: 755732:FLUTA_RS02685
uniprot id: F2IFT3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09630
gene id: 755732:FLUTA_RS09630
uniprot id: F2IJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

755732:FLUTA RS06690
gene id: 755732:FLUTA_RS06690
uniprot id: F2ICV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

755732:FLUTA RS15775
gene id: 755732:FLUTA_RS15775
uniprot id: F2IKK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS18770
gene id: 755732:FLUTA_RS18770
uniprot id: F2IFL1
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS16070
gene id: 755732:FLUTA_RS16070
uniprot id: F2I9K6
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

755732:FLUTA RS05955
gene id: 755732:FLUTA_RS05955
uniprot id: F2IB96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

755732:FLUTA RS09820
gene id: 755732:FLUTA_RS09820
uniprot id: F2IJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

755732:FLUTA RS16340
gene id: 755732:FLUTA_RS16340
uniprot id: F2IA65
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

755732:FLUTA RS04525
gene id: 755732:FLUTA_RS04525
uniprot id: F2IJL5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

755732:FLUTA RS06285
gene id: 755732:FLUTA_RS06285
uniprot id: F2IC22
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

755732:FLUTA RS03985
gene id: 755732:FLUTA_RS03985
uniprot id: F2IIT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

755732:FLUTA RS07340
gene id: 755732:FLUTA_RS07340
uniprot id: F2IED3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

755732:FLUTA RS12540
gene id: 755732:FLUTA_RS12540
uniprot id: F2IDU1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

755732:FLUTA RS12985
gene id: 755732:FLUTA_RS12985
uniprot id: F2IEN1
names: Similarity
messages: Belongs to the RelE toxin family.

755732:FLUTA RS05010
gene id: 755732:FLUTA_RS05010
uniprot id: F2I955
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

755732:FLUTA RS09560
gene id: 755732:FLUTA_RS09560
uniprot id: F2IJ39
names: Similarity
messages: Belongs to the pyruvate kinase family.

755732:FLUTA RS15365
gene id: 755732:FLUTA_RS15365
uniprot id: F2IJY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS19445
gene id: 755732:FLUTA_RS19445
uniprot id: F2IH46
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS20175
gene id: 755732:FLUTA_RS20175
uniprot id: F2IIP4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

755732:FLUTA RS19555
gene id: 755732:FLUTA_RS19555
uniprot id: F2IH68
names: Similarity
messages: Belongs to the peptidase M1 family.

755732:FLUTA RS03560
gene id: 755732:FLUTA_RS03560
uniprot id: F2II10
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

755732:FLUTA RS11130
gene id: 755732:FLUTA_RS11130
uniprot id: F2IAQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

755732:FLUTA RS03825
gene id: 755732:FLUTA_RS03825
uniprot id: F2II64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS03845
gene id: 755732:FLUTA_RS03845
uniprot id: F2IIR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

755732:FLUTA RS03910
gene id: 755732:FLUTA_RS03910
uniprot id: F2IIS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

755732:FLUTA RS15945
gene id: 755732:FLUTA_RS15945
uniprot id: F2I9I3
names: Subcellular Location Annotation
messages: Cytoplasm

755732:FLUTA RS03700
gene id: 755732:FLUTA_RS03700
uniprot id: F2II40
names: Similarity
messages: Belongs to the asparagine synthetase family.

755732:FLUTA RS11570
gene id: 755732:FLUTA_RS11570
uniprot id: F2IBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS19725
gene id: 755732:FLUTA_RS19725
uniprot id: F2IHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

755732:FLUTA RS13040
gene id: 755732:FLUTA_RS13040
uniprot id: F2IEP2
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

755732:FLUTA RS16970
gene id: 755732:FLUTA_RS16970
uniprot id: F2IBP0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

755732:FLUTA RS03835
gene id: 755732:FLUTA_RS03835
uniprot id: F2IIQ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

755732:FLUTA RS10475
gene id: 755732:FLUTA_RS10475
uniprot id: F2I9C2
names: Similarity
messages: Belongs to the ribF family.

755732:FLUTA RS17530
gene id: 755732:FLUTA_RS17530
uniprot id: F2ID64
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

755732:FLUTA RS01220
gene id: 755732:FLUTA_RS01220
uniprot id: F2ICM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

755732:FLUTA RS08840
gene id: 755732:FLUTA_RS08840
uniprot id: F2IHJ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS08615
gene id: 755732:FLUTA_RS08615
uniprot id: F2IHE4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS00055
gene id: 755732:FLUTA_RS00055
uniprot id: F2I9N0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

755732:FLUTA RS10820
gene id: 755732:FLUTA_RS10820
uniprot id: F2I9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

755732:FLUTA RS06210
gene id: 755732:FLUTA_RS06210
uniprot id: F2IC06
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

755732:FLUTA RS18190
gene id: 755732:FLUTA_RS18190
uniprot id: F2IE46
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Belongs to the spermidine/spermine synthase family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Homodimer or homotetramer.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS08670
gene id: 755732:FLUTA_RS08670
uniprot id: F2IHF5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS19565
gene id: 755732:FLUTA_RS19565
uniprot id: F2IH70
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS09350
gene id: 755732:FLUTA_RS09350
uniprot id: F2IIZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

755732:FLUTA RS00320
gene id: 755732:FLUTA_RS00320
uniprot id: F2IAE1
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11030
gene id: 755732:FLUTA_RS11030
uniprot id: F2IAN1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

755732:FLUTA RS16440
gene id: 755732:FLUTA_RS16440
uniprot id: F2IA84
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

755732:FLUTA RS08680
gene id: 755732:FLUTA_RS08680
uniprot id: F2IHF7
names: Subcellular Location Annotation
messages: Secreted

755732:FLUTA RS12165
gene id: 755732:FLUTA_RS12165
uniprot id: F2ID17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS14070
gene id: 755732:FLUTA_RS14070
uniprot id: F2IH05
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS04780
gene id: 755732:FLUTA_RS04780
uniprot id: F2IK56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS01385
gene id: 755732:FLUTA_RS01385
uniprot id: F2ICQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

755732:FLUTA RS19310
gene id: 755732:FLUTA_RS19310
uniprot id: F2IH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS13545
gene id: 755732:FLUTA_RS13545
uniprot id: F2IG43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

755732:FLUTA RS03795
gene id: 755732:FLUTA_RS03795
uniprot id: F2II58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

755732:FLUTA RS10735
gene id: 755732:FLUTA_RS10735
uniprot id: F2I9X4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

755732:FLUTA RS02730
gene id: 755732:FLUTA_RS02730
uniprot id: F2IFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

755732:FLUTA RS06735
gene id: 755732:FLUTA_RS06735
uniprot id: F2ICW3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

755732:FLUTA RS17945
gene id: 755732:FLUTA_RS17945
uniprot id: F2IDZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03725
gene id: 755732:FLUTA_RS03725
uniprot id: F2II44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

755732:FLUTA RS10225
gene id: 755732:FLUTA_RS10225
uniprot id: F2IKC6
names: Similarity
messages: Belongs to the LOG family.

755732:FLUTA RS17535
gene id: 755732:FLUTA_RS17535
uniprot id: F2ID65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

755732:FLUTA RS00600
gene id: 755732:FLUTA_RS00600
uniprot id: F2IB49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS20585
gene id: 755732:FLUTA_RS20585
uniprot id: F2IAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

755732:FLUTA RS06580
gene id: 755732:FLUTA_RS06580
uniprot id: F2ICT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

755732:FLUTA RS09680
gene id: 755732:FLUTA_RS09680
uniprot id: F2IJN2
names: Similarity
messages: Belongs to the ArsC family.

755732:FLUTA RS11075
gene id: 755732:FLUTA_RS11075
uniprot id: F2IAP0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03850
gene id: 755732:FLUTA_RS03850
uniprot id: F2IIR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

755732:FLUTA RS20310
gene id: 755732:FLUTA_RS20310
uniprot id: F2IJD6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS03470
gene id: 755732:FLUTA_RS03470
uniprot id: F2IHD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

755732:FLUTA RS10510
gene id: 755732:FLUTA_RS10510
uniprot id: F2I9C9
names: Similarity
messages: Belongs to the AIR synthase family.

755732:FLUTA RS01880
gene id: 755732:FLUTA_RS01880
uniprot id: F2IE65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

755732:FLUTA RS16430
gene id: 755732:FLUTA_RS16430
uniprot id: F2IA82
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

755732:FLUTA RS13550
gene id: 755732:FLUTA_RS13550
uniprot id: F2IG44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

755732:FLUTA RS02600
gene id: 755732:FLUTA_RS02600
uniprot id: F2IFR6
names: Similarity
messages: Belongs to the arginase family.

755732:FLUTA RS11525
gene id: 755732:FLUTA_RS11525
uniprot id: F2IBH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS04520
gene id: 755732:FLUTA_RS04520
uniprot id: F2IJL4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

755732:FLUTA RS18105
gene id: 755732:FLUTA_RS18105
uniprot id: F2IE29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS09835
gene id: 755732:FLUTA_RS09835
uniprot id: F2IJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS01020
gene id: 755732:FLUTA_RS01020
uniprot id: F2IBY7
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09905
gene id: 755732:FLUTA_RS09905
uniprot id: F2IJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

755732:FLUTA RS01310
gene id: 755732:FLUTA_RS01310
uniprot id: F2ICP3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS04555
gene id: 755732:FLUTA_RS04555
uniprot id: F2IK10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

755732:FLUTA RS07660
gene id: 755732:FLUTA_RS07660
uniprot id: F2IF47
names: Similarity
messages: Belongs to the NodU/CmcH family.

755732:FLUTA RS21905
gene id: 755732:FLUTA_RS21905
uniprot id: F2IH14
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS11895
gene id: 755732:FLUTA_RS11895
uniprot id: F2ICB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

755732:FLUTA RS09675
gene id: 755732:FLUTA_RS09675
uniprot id: F2IJN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

755732:FLUTA RS19275
gene id: 755732:FLUTA_RS19275
uniprot id: F2IH12
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS00020
gene id: 755732:FLUTA_RS00020
uniprot id: F2I9M3
names: Similarity
messages: Belongs to the IMPACT family.

755732:FLUTA RS17960
gene id: 755732:FLUTA_RS17960
uniprot id: F2IE00
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

755732:FLUTA RS06990
gene id: 755732:FLUTA_RS06990
uniprot id: F2IDL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

755732:FLUTA RS19620
gene id: 755732:FLUTA_RS19620
uniprot id: F2IHT6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS04535
gene id: 755732:FLUTA_RS04535
uniprot id: F2IK06
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS21185
gene id: 755732:FLUTA_RS21185
uniprot id: F2IGZ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

755732:FLUTA RS10420
gene id: 755732:FLUTA_RS10420
uniprot id: F2I9B1
names: Similarity
messages: Belongs to the TlyA family.

755732:FLUTA RS14285
gene id: 755732:FLUTA_RS14285
uniprot id: F2IHQ2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

755732:FLUTA RS17015
gene id: 755732:FLUTA_RS17015
uniprot id: F2IBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS20130
gene id: 755732:FLUTA_RS20130
uniprot id: F2IIN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

755732:FLUTA RS05530
gene id: 755732:FLUTA_RS05530
uniprot id: F2IAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

755732:FLUTA RS01050
gene id: 755732:FLUTA_RS01050
uniprot id: F2IBZ3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS16370
gene id: 755732:FLUTA_RS16370
uniprot id: F2IA70
names: Similarity
messages: Belongs to the ClpA/ClpB family.

755732:FLUTA RS12445
gene id: 755732:FLUTA_RS12445
uniprot id: F2IDS6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

755732:FLUTA RS07160
gene id: 755732:FLUTA_RS07160
uniprot id: F2IDP8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS12825
gene id: 755732:FLUTA_RS12825
uniprot id: F2IEK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

755732:FLUTA RS00125
gene id: 755732:FLUTA_RS00125
uniprot id: F2IAA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

755732:FLUTA RS03800
gene id: 755732:FLUTA_RS03800
uniprot id: F2II59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

755732:FLUTA RS17050
gene id: 755732:FLUTA_RS17050
uniprot id: F2IBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

755732:FLUTA RS04470
gene id: 755732:FLUTA_RS04470
uniprot id: F2IJK4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

755732:FLUTA RS11670
gene id: 755732:FLUTA_RS11670
uniprot id: F2IBK8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11805
gene id: 755732:FLUTA_RS11805
uniprot id: F2IC97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

755732:FLUTA RS04660
gene id: 755732:FLUTA_RS04660
uniprot id: F2IK31
names: Similarity
messages: Belongs to the aspartokinase family.

755732:FLUTA RS13080
gene id: 755732:FLUTA_RS13080
uniprot id: F2IFA6
names: Similarity
messages: Belongs to the ComB family.

755732:FLUTA RS18060
gene id: 755732:FLUTA_RS18060
uniprot id: F2IE20
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11135
gene id: 755732:FLUTA_RS11135
uniprot id: F2IAQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

755732:FLUTA RS14120
gene id: 755732:FLUTA_RS14120
uniprot id: F2IHL8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS00525
gene id: 755732:FLUTA_RS00525
uniprot id: F2IB33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

755732:FLUTA RS16475
gene id: 755732:FLUTA_RS16475
uniprot id: F2IA91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

755732:FLUTA RS01360
gene id: 755732:FLUTA_RS01360
uniprot id: F2ICQ3
names: Similarity
messages: Belongs to the thioredoxin family.

755732:FLUTA RS03905
gene id: 755732:FLUTA_RS03905
uniprot id: F2IIS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

755732:FLUTA RS07510
gene id: 755732:FLUTA_RS07510
uniprot id: F2IEG7
names: Similarity
messages: Belongs to the phosphoribulokinase family.

755732:FLUTA RS01820
gene id: 755732:FLUTA_RS01820
uniprot id: F2IE53
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS05535
gene id: 755732:FLUTA_RS05535
uniprot id: F2IAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

755732:FLUTA RS01460
gene id: 755732:FLUTA_RS01460
uniprot id: F2ICS3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS07630
gene id: 755732:FLUTA_RS07630
uniprot id: F2IF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

755732:FLUTA RS00005
gene id: 755732:FLUTA_RS00005
uniprot id: F2I9L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

755732:FLUTA RS00675
gene id: 755732:FLUTA_RS00675
uniprot id: F2IB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

755732:FLUTA RS00545
gene id: 755732:FLUTA_RS00545
uniprot id: F2IB37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03275
gene id: 755732:FLUTA_RS03275
uniprot id: F2IH96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

755732:FLUTA RS03380
gene id: 755732:FLUTA_RS03380
uniprot id: F2IHB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

755732:FLUTA RS09510
gene id: 755732:FLUTA_RS09510
uniprot id: F2IJ28
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

755732:FLUTA RS12775
gene id: 755732:FLUTA_RS12775
uniprot id: F2IEJ0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

755732:FLUTA RS04710
gene id: 755732:FLUTA_RS04710
uniprot id: F2IK42
names: Similarity
messages: Belongs to the DNA photolyase family.

755732:FLUTA RS07065
gene id: 755732:FLUTA_RS07065
uniprot id: F2IDM9
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS10025
gene id: 755732:FLUTA_RS10025
uniprot id: F2IK87
names: Similarity
messages: Belongs to the peptidase S8 family.

755732:FLUTA RS00930
gene id: 755732:FLUTA_RS00930
uniprot id: F2IBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

755732:FLUTA RS13085
gene id: 755732:FLUTA_RS13085
uniprot id: F2IFA7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

755732:FLUTA RS05845
gene id: 755732:FLUTA_RS05845
uniprot id: F2IAM5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS03600
gene id: 755732:FLUTA_RS03600
uniprot id: F2II18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

755732:FLUTA RS11355
gene id: 755732:FLUTA_RS11355
uniprot id: F2IBE5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

755732:FLUTA RS03035
gene id: 755732:FLUTA_RS03035
uniprot id: F2IGJ7
names: Similarity
messages: Belongs to the pirin family.

755732:FLUTA RS05725
gene id: 755732:FLUTA_RS05725
uniprot id: F2IAK3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS16870
gene id: 755732:FLUTA_RS16870
uniprot id: F2IBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

755732:FLUTA RS01450
gene id: 755732:FLUTA_RS01450
uniprot id: F2ICS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

755732:FLUTA RS05635
gene id: 755732:FLUTA_RS05635
uniprot id: F2IAI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS01345
gene id: 755732:FLUTA_RS01345
uniprot id: F2ICQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

755732:FLUTA RS18195
gene id: 755732:FLUTA_RS18195
uniprot id: F2IE47
names: Similarity
messages: Belongs to the arginase family.

755732:FLUTA RS06320
gene id: 755732:FLUTA_RS06320
uniprot id: F2IC29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS14415
gene id: 755732:FLUTA_RS14415
uniprot id: F2IID0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

755732:FLUTA RS04725
gene id: 755732:FLUTA_RS04725
uniprot id: F2IK45
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

755732:FLUTA RS16485
gene id: 755732:FLUTA_RS16485
uniprot id: F2IAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS06695
gene id: 755732:FLUTA_RS06695
uniprot id: F2ICV5
names: Similarity
messages: Belongs to the UPF0102 family.

755732:FLUTA RS00370
gene id: 755732:FLUTA_RS00370
uniprot id: F2IAF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

755732:FLUTA RS17750
gene id: 755732:FLUTA_RS17750
uniprot id: F2IDA9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

755732:FLUTA RS16025
gene id: 755732:FLUTA_RS16025
uniprot id: F2I9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

755732:FLUTA RS03865
gene id: 755732:FLUTA_RS03865
uniprot id: F2IIR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS07945
gene id: 755732:FLUTA_RS07945
uniprot id: F2IFV5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS19220
gene id: 755732:FLUTA_RS19220
uniprot id: F2IGE8
names: Similarity
messages: Belongs to the pirin family.

755732:FLUTA RS07905
gene id: 755732:FLUTA_RS07905
uniprot id: F2IF94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

755732:FLUTA RS10805
gene id: 755732:FLUTA_RS10805
uniprot id: F2I9Y3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

755732:FLUTA RS03790
gene id: 755732:FLUTA_RS03790
uniprot id: F2II57
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

755732:FLUTA RS00180
gene id: 755732:FLUTA_RS00180
uniprot id: F2IAB3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS05005
gene id: 755732:FLUTA_RS05005
uniprot id: F2I954
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

755732:FLUTA RS12650
gene id: 755732:FLUTA_RS12650
uniprot id: F2IDW3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

755732:FLUTA RS05585
gene id: 755732:FLUTA_RS05585
uniprot id: F2IAH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

755732:FLUTA RS19355
gene id: 755732:FLUTA_RS19355
uniprot id: F2IH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

755732:FLUTA RS01240
gene id: 755732:FLUTA_RS01240
uniprot id: F2ICN1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

755732:FLUTA RS16480
gene id: 755732:FLUTA_RS16480
uniprot id: F2IA92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS03740
gene id: 755732:FLUTA_RS03740
uniprot id: F2II47
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

755732:FLUTA RS05615
gene id: 755732:FLUTA_RS05615
uniprot id: F2IAI2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

755732:FLUTA RS13825
gene id: 755732:FLUTA_RS13825
uniprot id: F2IGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

755732:FLUTA RS17665
gene id: 755732:FLUTA_RS17665
uniprot id: F2ID91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

755732:FLUTA RS01175
gene id: 755732:FLUTA_RS01175
uniprot id: F2ICL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

755732:FLUTA RS00665
gene id: 755732:FLUTA_RS00665
uniprot id: F2IB62
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS03280
gene id: 755732:FLUTA_RS03280
uniprot id: F2IH97
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

755732:FLUTA RS19580
gene id: 755732:FLUTA_RS19580
uniprot id: F2IHS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

755732:FLUTA RS07755
gene id: 755732:FLUTA_RS07755
uniprot id: F2IF64
names: Similarity
messages: Belongs to the LacAB/RpiB family.

755732:FLUTA RS11710
gene id: 755732:FLUTA_RS11710
uniprot id: F2IC78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS20095
gene id: 755732:FLUTA_RS20095
uniprot id: F2IIM8
names: Similarity
messages: Belongs to the UPF0246 family.

755732:FLUTA RS03785
gene id: 755732:FLUTA_RS03785
uniprot id: F2II56
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

755732:FLUTA RS19695
gene id: 755732:FLUTA_RS19695
uniprot id: F2IHV1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS20665
gene id: 755732:FLUTA_RS20665
uniprot id: F2IED5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

755732:FLUTA RS01350
gene id: 755732:FLUTA_RS01350
uniprot id: F2ICQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

755732:FLUTA RS15070
gene id: 755732:FLUTA_RS15070
uniprot id: F2IJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS08675
gene id: 755732:FLUTA_RS08675
uniprot id: F2IHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

755732:FLUTA RS10790
gene id: 755732:FLUTA_RS10790
uniprot id: F2I9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

755732:FLUTA RS03340
gene id: 755732:FLUTA_RS03340
uniprot id: F2IHA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS17420
gene id: 755732:FLUTA_RS17420
uniprot id: F2ICI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

755732:FLUTA RS15835
gene id: 755732:FLUTA_RS15835
uniprot id: F2I9G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

755732:FLUTA RS09845
gene id: 755732:FLUTA_RS09845
uniprot id: F2IJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

755732:FLUTA RS03175
gene id: 755732:FLUTA_RS03175
uniprot id: F2IH76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

755732:FLUTA RS07005
gene id: 755732:FLUTA_RS07005
uniprot id: F2IDL7
names: Similarity
messages: Belongs to the peptidase S66 family.

755732:FLUTA RS05805
gene id: 755732:FLUTA_RS05805
uniprot id: F2IAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

755732:FLUTA RS03860
gene id: 755732:FLUTA_RS03860
uniprot id: F2IIR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

755732:FLUTA RS13590
gene id: 755732:FLUTA_RS13590
uniprot id: F2IG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

755732:FLUTA RS04680
gene id: 755732:FLUTA_RS04680
uniprot id: F2IK35
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS08645
gene id: 755732:FLUTA_RS08645
uniprot id: F2IHF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

755732:FLUTA RS00905
gene id: 755732:FLUTA_RS00905
uniprot id: F2IBW3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

755732:FLUTA RS19585
gene id: 755732:FLUTA_RS19585
uniprot id: F2IHS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS19385
gene id: 755732:FLUTA_RS19385
uniprot id: F2IH34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

755732:FLUTA RS03650
gene id: 755732:FLUTA_RS03650
uniprot id: F2II28
names: Similarity
messages: Belongs to the asparagine synthetase family.

755732:FLUTA RS11640
gene id: 755732:FLUTA_RS11640
uniprot id: F2IBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

755732:FLUTA RS14075
gene id: 755732:FLUTA_RS14075
uniprot id: F2IHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

755732:FLUTA RS00985
gene id: 755732:FLUTA_RS00985
uniprot id: F2IBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

755732:FLUTA RS08025
gene id: 755732:FLUTA_RS08025
uniprot id: F2IFX1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

755732:FLUTA RS05895
gene id: 755732:FLUTA_RS05895
uniprot id: F2IB84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

755732:FLUTA RS20225
gene id: 755732:FLUTA_RS20225
uniprot id: F2IIQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

755732:FLUTA RS20210
gene id: 755732:FLUTA_RS20210
uniprot id: F2IIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS05700
gene id: 755732:FLUTA_RS05700
uniprot id: F2IAJ8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

755732:FLUTA RS18360
gene id: 755732:FLUTA_RS18360
uniprot id: F2IES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

755732:FLUTA RS06995
gene id: 755732:FLUTA_RS06995
uniprot id: F2IDL5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS17210
gene id: 755732:FLUTA_RS17210
uniprot id: F2ICE4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

755732:FLUTA RS16010
gene id: 755732:FLUTA_RS16010
uniprot id: F2I9J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

755732:FLUTA RS02440
gene id: 755732:FLUTA_RS02440
uniprot id: F2IF25
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

755732:FLUTA RS02345
gene id: 755732:FLUTA_RS02345
uniprot id: F2IF06
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11955
gene id: 755732:FLUTA_RS11955
uniprot id: F2ICC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

755732:FLUTA RS08585
gene id: 755732:FLUTA_RS08585
uniprot id: F2IGT6
names: Similarity
messages: Belongs to the asparaginase 1 family.

755732:FLUTA RS00200
gene id: 755732:FLUTA_RS00200
uniprot id: F2IAB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

755732:FLUTA RS21030
gene id: 755732:FLUTA_RS21030
uniprot id: F2IEP8
names: Similarity
messages: Belongs to the peptidase C40 family.

755732:FLUTA RS08715
gene id: 755732:FLUTA_RS08715
uniprot id: F2IHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

755732:FLUTA RS16915
gene id: 755732:FLUTA_RS16915
uniprot id: F2IBM9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

755732:FLUTA RS10440
gene id: 755732:FLUTA_RS10440
uniprot id: F2I9B5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

755732:FLUTA RS20415
gene id: 755732:FLUTA_RS20415
uniprot id: F2IDC7
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS08625
gene id: 755732:FLUTA_RS08625
uniprot id: F2IHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

755732:FLUTA RS07530
gene id: 755732:FLUTA_RS07530
uniprot id: F2IEH1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

755732:FLUTA RS05810
gene id: 755732:FLUTA_RS05810
uniprot id: F2IAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

755732:FLUTA RS07435
gene id: 755732:FLUTA_RS07435
uniprot id: F2IEF2
names: Similarity
messages: Belongs to the universal stress protein A family.

755732:FLUTA RS07650
gene id: 755732:FLUTA_RS07650
uniprot id: F2IF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

755732:FLUTA RS15755
gene id: 755732:FLUTA_RS15755
uniprot id: F2IKK1
names: Similarity
messages: Belongs to the UPF0758 family.

755732:FLUTA RS07795
gene id: 755732:FLUTA_RS07795
uniprot id: F2IF72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

755732:FLUTA RS05905
gene id: 755732:FLUTA_RS05905
uniprot id: F2IB86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

755732:FLUTA RS02090
gene id: 755732:FLUTA_RS02090
uniprot id: F2IEA3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

755732:FLUTA RS17340
gene id: 755732:FLUTA_RS17340
uniprot id: F2ICH1
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS10970
gene id: 755732:FLUTA_RS10970
uniprot id: F2IA16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

755732:FLUTA RS12400
gene id: 755732:FLUTA_RS12400
uniprot id: F2IDR7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

755732:FLUTA RS19105
gene id: 755732:FLUTA_RS19105
uniprot id: F2IGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS03660
gene id: 755732:FLUTA_RS03660
uniprot id: F2II30
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

755732:FLUTA RS10120
gene id: 755732:FLUTA_RS10120
uniprot id: F2IKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

755732:FLUTA RS17500
gene id: 755732:FLUTA_RS17500
uniprot id: F2ICK3
names: Similarity
messages: Belongs to the universal stress protein A family.

755732:FLUTA RS18035
gene id: 755732:FLUTA_RS18035
uniprot id: F2IE15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

755732:FLUTA RS19875
gene id: 755732:FLUTA_RS19875
uniprot id: F2IHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

755732:FLUTA RS09590
gene id: 755732:FLUTA_RS09590
uniprot id: F2IJ45
names: Similarity
messages: Belongs to the SCO1/2 family.

755732:FLUTA RS02485
gene id: 755732:FLUTA_RS02485
uniprot id: F2IFP1
names: Similarity
messages: Belongs to the peptidase S41A family.

755732:FLUTA RS03260
gene id: 755732:FLUTA_RS03260
uniprot id: F2IH93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

755732:FLUTA RS05170
gene id: 755732:FLUTA_RS05170
uniprot id: F2I9N6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

755732:FLUTA RS02350
gene id: 755732:FLUTA_RS02350
uniprot id: F2IF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS07870
gene id: 755732:FLUTA_RS07870
uniprot id: F2IF87
names: Similarity
messages: Belongs to the peptidase C1 family.

755732:FLUTA RS09190
gene id: 755732:FLUTA_RS09190
uniprot id: F2IIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

755732:FLUTA RS18555
gene id: 755732:FLUTA_RS18555
uniprot id: F2IFG9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS11155
gene id: 755732:FLUTA_RS11155
uniprot id: F2IAQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

755732:FLUTA RS06250
gene id: 755732:FLUTA_RS06250
uniprot id: F2IC15
names: Similarity
messages: Belongs to the peptidase M17 family.

755732:FLUTA RS17310
gene id: 755732:FLUTA_RS17310
uniprot id: F2ICG5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS00245
gene id: 755732:FLUTA_RS00245
uniprot id: F2IAC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS10995
gene id: 755732:FLUTA_RS10995
uniprot id: F2IA21
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

755732:FLUTA RS11645
gene id: 755732:FLUTA_RS11645
uniprot id: F2IBK3
names: Similarity
messages: Belongs to the UPF0111 family.

755732:FLUTA RS07125
gene id: 755732:FLUTA_RS07125
uniprot id: F2IDP1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

755732:FLUTA RS00910
gene id: 755732:FLUTA_RS00910
uniprot id: F2IBW4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS07300
gene id: 755732:FLUTA_RS07300
uniprot id: F2IEC5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

755732:FLUTA RS15805
gene id: 755732:FLUTA_RS15805
uniprot id: F2I9F6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS15680
gene id: 755732:FLUTA_RS15680
uniprot id: F2IKI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

755732:FLUTA RS17930
gene id: 755732:FLUTA_RS17930
uniprot id: F2IDZ4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

755732:FLUTA RS12770
gene id: 755732:FLUTA_RS12770
uniprot id: F2IEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

755732:FLUTA RS12835
gene id: 755732:FLUTA_RS12835
uniprot id: F2IEK2
names: Subcellular Location Annotation
messages: Cytoplasm

755732:FLUTA RS07490
gene id: 755732:FLUTA_RS07490
uniprot id: F2IEG3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

755732:FLUTA RS13020
gene id: 755732:FLUTA_RS13020
uniprot id: F2IEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

755732:FLUTA RS13900
gene id: 755732:FLUTA_RS13900
uniprot id: F2IGX2
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS12095
gene id: 755732:FLUTA_RS12095
uniprot id: F2ID04
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

755732:FLUTA RS19315
gene id: 755732:FLUTA_RS19315
uniprot id: F2IH20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS00580
gene id: 755732:FLUTA_RS00580
uniprot id: F2IB45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS14820
gene id: 755732:FLUTA_RS14820
uniprot id: F2IJ66
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

755732:FLUTA RS19270
gene id: 755732:FLUTA_RS19270
uniprot id: F2IH11
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS12265
gene id: 755732:FLUTA_RS12265
uniprot id: F2ID38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

755732:FLUTA RS03810
gene id: 755732:FLUTA_RS03810
uniprot id: F2II61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

755732:FLUTA RS03920
gene id: 755732:FLUTA_RS03920
uniprot id: F2IIS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

755732:FLUTA RS12420
gene id: 755732:FLUTA_RS12420
uniprot id: F2IDS1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS11585
gene id: 755732:FLUTA_RS11585
uniprot id: F2IBJ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

755732:FLUTA RS10895
gene id: 755732:FLUTA_RS10895
uniprot id: F2IA01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

755732:FLUTA RS12425
gene id: 755732:FLUTA_RS12425
uniprot id: F2IDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

755732:FLUTA RS12335
gene id: 755732:FLUTA_RS12335
uniprot id: F2ID52
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

755732:FLUTA RS04640
gene id: 755732:FLUTA_RS04640
uniprot id: F2IK27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS08865
gene id: 755732:FLUTA_RS08865
uniprot id: F2IHJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

755732:FLUTA RS12740
gene id: 755732:FLUTA_RS12740
uniprot id: F2IEI3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

755732:FLUTA RS02610
gene id: 755732:FLUTA_RS02610
uniprot id: F2IFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

755732:FLUTA RS02650
gene id: 755732:FLUTA_RS02650
uniprot id: F2IFS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS19840
gene id: 755732:FLUTA_RS19840
uniprot id: F2IHY0
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

755732:FLUTA RS00500
gene id: 755732:FLUTA_RS00500
uniprot id: F2IB28
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS04100
gene id: 755732:FLUTA_RS04100
uniprot id: F2IIW2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

755732:FLUTA RS01300
gene id: 755732:FLUTA_RS01300
uniprot id: F2ICP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

755732:FLUTA RS05930
gene id: 755732:FLUTA_RS05930
uniprot id: F2IB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

755732:FLUTA RS11900
gene id: 755732:FLUTA_RS11900
uniprot id: F2ICB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

755732:FLUTA RS05715
gene id: 755732:FLUTA_RS05715
uniprot id: F2IAK1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

755732:FLUTA RS03930
gene id: 755732:FLUTA_RS03930
uniprot id: F2IIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

755732:FLUTA RS15570
gene id: 755732:FLUTA_RS15570
uniprot id: F2IKG4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

755732:FLUTA RS07725
gene id: 755732:FLUTA_RS07725
uniprot id: F2IF59
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

755732:FLUTA RS09445
gene id: 755732:FLUTA_RS09445
uniprot id: F2IJ15
names: Similarity
messages: Belongs to the MreC family.

755732:FLUTA RS11345
gene id: 755732:FLUTA_RS11345
uniprot id: F2IBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

755732:FLUTA RS11730
gene id: 755732:FLUTA_RS11730
uniprot id: F2IC82
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS03895
gene id: 755732:FLUTA_RS03895
uniprot id: F2IIS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

755732:FLUTA RS13785
gene id: 755732:FLUTA_RS13785
uniprot id: F2IGU9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

755732:FLUTA RS11440
gene id: 755732:FLUTA_RS11440
uniprot id: F2IBG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS09610
gene id: 755732:FLUTA_RS09610
uniprot id: F2IJL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

755732:FLUTA RS05610
gene id: 755732:FLUTA_RS05610
uniprot id: F2IAI1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

755732:FLUTA RS19865
gene id: 755732:FLUTA_RS19865
uniprot id: F2IHY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

755732:FLUTA RS00495
gene id: 755732:FLUTA_RS00495
uniprot id: F2IB27
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

755732:FLUTA RS19425
gene id: 755732:FLUTA_RS19425
uniprot id: F2IH42
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

755732:FLUTA RS06685
gene id: 755732:FLUTA_RS06685
uniprot id: F2ICV3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS05340
gene id: 755732:FLUTA_RS05340
uniprot id: F2I9S2
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

755732:FLUTA RS10485
gene id: 755732:FLUTA_RS10485
uniprot id: F2I9C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

755732:FLUTA RS17955
gene id: 755732:FLUTA_RS17955
uniprot id: F2IDZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS00380
gene id: 755732:FLUTA_RS00380
uniprot id: F2IAF3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

755732:FLUTA RS00090
gene id: 755732:FLUTA_RS00090
uniprot id: F2IA95
names: Similarity
messages: Belongs to the GbsR family.

755732:FLUTA RS11295
gene id: 755732:FLUTA_RS11295
uniprot id: F2IAT6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

755732:FLUTA RS00290
gene id: 755732:FLUTA_RS00290
uniprot id: F2IAD5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

755732:FLUTA RS11935
gene id: 755732:FLUTA_RS11935
uniprot id: F2ICC3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

755732:FLUTA RS20020
gene id: 755732:FLUTA_RS20020
uniprot id: F2IIL2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

755732:FLUTA RS15985
gene id: 755732:FLUTA_RS15985
uniprot id: F2I9J0
names: Similarity
messages: Belongs to the universal stress protein A family.

755732:FLUTA RS12225
gene id: 755732:FLUTA_RS12225
uniprot id: F2ID29
names: Similarity
messages: Belongs to the Fur family.

755732:FLUTA RS07595
gene id: 755732:FLUTA_RS07595
uniprot id: F2IF34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

755732:FLUTA RS01245
gene id: 755732:FLUTA_RS01245
uniprot id: F2ICN2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

755732:FLUTA RS00770
gene id: 755732:FLUTA_RS00770
uniprot id: F2IBT6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS00040
gene id: 755732:FLUTA_RS00040
uniprot id: F2I9M7
names: Subcellular Location Annotation
messages: Secreted

755732:FLUTA RS09640
gene id: 755732:FLUTA_RS09640
uniprot id: F2IJM3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

755732:FLUTA RS12135
gene id: 755732:FLUTA_RS12135
uniprot id: F2ID11
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

755732:FLUTA RS10550
gene id: 755732:FLUTA_RS10550
uniprot id: F2I9D7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

755732:FLUTA RS03830
gene id: 755732:FLUTA_RS03830
uniprot id: F2IIQ8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS07805
gene id: 755732:FLUTA_RS07805
uniprot id: F2IF74
names: Similarity
messages: Belongs to the universal stress protein A family.

755732:FLUTA RS17720
gene id: 755732:FLUTA_RS17720
uniprot id: F2IDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

755732:FLUTA RS10810
gene id: 755732:FLUTA_RS10810
uniprot id: F2I9Y4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

755732:FLUTA RS16365
gene id: 755732:FLUTA_RS16365
uniprot id: F2IA69
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS06825
gene id: 755732:FLUTA_RS06825
uniprot id: F2ICX9
names: Similarity
messages: Belongs to the catalase family.

755732:FLUTA RS02540
gene id: 755732:FLUTA_RS02540
uniprot id: F2IFQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

755732:FLUTA RS19485
gene id: 755732:FLUTA_RS19485
uniprot id: F2IH54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

755732:FLUTA RS17465
gene id: 755732:FLUTA_RS17465
uniprot id: F2ICJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

755732:FLUTA RS13410
gene id: 755732:FLUTA_RS13410
uniprot id: F2IG17
names: Similarity
messages: Belongs to the BshC family.

755732:FLUTA RS15730
gene id: 755732:FLUTA_RS15730
uniprot id: F2IKJ6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

755732:FLUTA RS19550
gene id: 755732:FLUTA_RS19550
uniprot id: F2IH67
names: Subcellular Location Annotation
messages: Cell inner membrane

755732:FLUTA RS09490
gene id: 755732:FLUTA_RS09490
uniprot id: F2IJ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS17765
gene id: 755732:FLUTA_RS17765
uniprot id: F2IDB2
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS12815
gene id: 755732:FLUTA_RS12815
uniprot id: F2IEJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS14940
gene id: 755732:FLUTA_RS14940
uniprot id: F2IJ90
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

755732:FLUTA RS06660
gene id: 755732:FLUTA_RS06660
uniprot id: F2ICU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

755732:FLUTA RS12235
gene id: 755732:FLUTA_RS12235
uniprot id: F2ID31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

755732:FLUTA RS01810
gene id: 755732:FLUTA_RS01810
uniprot id: F2IE51
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS08200
gene id: 755732:FLUTA_RS08200
uniprot id: F2IG06
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

755732:FLUTA RS04300
gene id: 755732:FLUTA_RS04300
uniprot id: F2IJH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

755732:FLUTA RS09805
gene id: 755732:FLUTA_RS09805
uniprot id: F2IJQ8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

755732:FLUTA RS12535
gene id: 755732:FLUTA_RS12535
uniprot id: F2IDU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS10835
gene id: 755732:FLUTA_RS10835
uniprot id: F2I9Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

755732:FLUTA RS11185
gene id: 755732:FLUTA_RS11185
uniprot id: F2IAR3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

755732:FLUTA RS00420
gene id: 755732:FLUTA_RS00420
uniprot id: F2IB13
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

755732:FLUTA RS01225
gene id: 755732:FLUTA_RS01225
uniprot id: F2ICM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

755732:FLUTA RS10865
gene id: 755732:FLUTA_RS10865
uniprot id: F2I9Z5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS11420
gene id: 755732:FLUTA_RS11420
uniprot id: F2IBF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

755732:FLUTA RS09940
gene id: 755732:FLUTA_RS09940
uniprot id: F2IK71
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

755732:FLUTA RS03080
gene id: 755732:FLUTA_RS03080
uniprot id: F2IGK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

755732:FLUTA RS08755
gene id: 755732:FLUTA_RS08755
uniprot id: F2IHH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS08825
gene id: 755732:FLUTA_RS08825
uniprot id: F2IHI7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

755732:FLUTA RS01075
gene id: 755732:FLUTA_RS01075
uniprot id: F2IBZ8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

755732:FLUTA RS11375
gene id: 755732:FLUTA_RS11375
uniprot id: F2IBE9
names: Similarity
messages: Belongs to the NAD synthetase family.

755732:FLUTA RS12000
gene id: 755732:FLUTA_RS12000
uniprot id: F2ICD1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

755732:FLUTA RS03915
gene id: 755732:FLUTA_RS03915
uniprot id: F2IIS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

755732:FLUTA RS13840
gene id: 755732:FLUTA_RS13840
uniprot id: F2IGV9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

755732:FLUTA RS03935
gene id: 755732:FLUTA_RS03935
uniprot id: F2IIS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

755732:FLUTA RS04010
gene id: 755732:FLUTA_RS04010
uniprot id: F2IIU4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

755732:FLUTA RS11225
gene id: 755732:FLUTA_RS11225
uniprot id: F2IAS1
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS07420
gene id: 755732:FLUTA_RS07420
uniprot id: F2IEE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS14300
gene id: 755732:FLUTA_RS14300
uniprot id: F2IHQ5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

755732:FLUTA RS20270
gene id: 755732:FLUTA_RS20270
uniprot id: F2IJC8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

755732:FLUTA RS02585
gene id: 755732:FLUTA_RS02585
uniprot id: F2IFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

755732:FLUTA RS16525
gene id: 755732:FLUTA_RS16525
uniprot id: F2IAV4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS11055
gene id: 755732:FLUTA_RS11055
uniprot id: F2IAN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

755732:FLUTA RS09840
gene id: 755732:FLUTA_RS09840
uniprot id: F2IJR5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS03625
gene id: 755732:FLUTA_RS03625
uniprot id: F2II23
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

755732:FLUTA RS05750
gene id: 755732:FLUTA_RS05750
uniprot id: F2IAK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

755732:FLUTA RS02570
gene id: 755732:FLUTA_RS02570
uniprot id: F2IFR0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

755732:FLUTA RS10920
gene id: 755732:FLUTA_RS10920
uniprot id: F2IA06
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09785
gene id: 755732:FLUTA_RS09785
uniprot id: F2IJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS07445
gene id: 755732:FLUTA_RS07445
uniprot id: F2IEF4
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS01205
gene id: 755732:FLUTA_RS01205
uniprot id: F2ICM4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

755732:FLUTA RS09575
gene id: 755732:FLUTA_RS09575
uniprot id: F2IJ42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS10305
gene id: 755732:FLUTA_RS10305
uniprot id: F2I988
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

755732:FLUTA RS17295
gene id: 755732:FLUTA_RS17295
uniprot id: F2ICG2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

755732:FLUTA RS17970
gene id: 755732:FLUTA_RS17970
uniprot id: F2IE02
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

755732:FLUTA RS19575
gene id: 755732:FLUTA_RS19575
uniprot id: F2IHS7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

755732:FLUTA RS00780
gene id: 755732:FLUTA_RS00780
uniprot id: F2IBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

755732:FLUTA RS16030
gene id: 755732:FLUTA_RS16030
uniprot id: F2I9J9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

755732:FLUTA RS12260
gene id: 755732:FLUTA_RS12260
uniprot id: F2ID36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

755732:FLUTA RS06840
gene id: 755732:FLUTA_RS06840
uniprot id: F2ICY3
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

755732:FLUTA RS14045
gene id: 755732:FLUTA_RS14045
uniprot id: F2IH00
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

755732:FLUTA RS14185
gene id: 755732:FLUTA_RS14185
uniprot id: F2IHN2
names: Similarity
messages: Belongs to the threonine aldolase family.

755732:FLUTA RS10500
gene id: 755732:FLUTA_RS10500
uniprot id: F2I9C7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

755732:FLUTA RS16095
gene id: 755732:FLUTA_RS16095
uniprot id: F2I9L1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

755732:FLUTA RS11940
gene id: 755732:FLUTA_RS11940
uniprot id: F2ICC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

755732:FLUTA RS14055
gene id: 755732:FLUTA_RS14055
uniprot id: F2IH02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

755732:FLUTA RS17900
gene id: 755732:FLUTA_RS17900
uniprot id: F2IDY8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS09215
gene id: 755732:FLUTA_RS09215
uniprot id: F2IIB8
names: Similarity
messages: Belongs to the GARS family.

755732:FLUTA RS14380
gene id: 755732:FLUTA_RS14380
uniprot id: F2IHS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS00060
gene id: 755732:FLUTA_RS00060
uniprot id: F2I9N1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

755732:FLUTA RS10815
gene id: 755732:FLUTA_RS10815
uniprot id: F2I9Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

755732:FLUTA RS12475
gene id: 755732:FLUTA_RS12475
uniprot id: F2IDT2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

755732:FLUTA RS09885
gene id: 755732:FLUTA_RS09885
uniprot id: F2IJS3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

755732:FLUTA RS17800
gene id: 755732:FLUTA_RS17800
uniprot id: F2IDB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS09765
gene id: 755732:FLUTA_RS09765
uniprot id: F2IJQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

755732:FLUTA RS01045
gene id: 755732:FLUTA_RS01045
uniprot id: F2IBZ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

755732:FLUTA RS06865
gene id: 755732:FLUTA_RS06865
uniprot id: F2ICY8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

755732:FLUTA RS09345
gene id: 755732:FLUTA_RS09345
uniprot id: F2IIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

755732:FLUTA RS17575
gene id: 755732:FLUTA_RS17575
uniprot id: F2ID73
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS13370
gene id: 755732:FLUTA_RS13370
uniprot id: F2IFF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

755732:FLUTA RS05185
gene id: 755732:FLUTA_RS05185
uniprot id: F2I9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

755732:FLUTA RS03305
gene id: 755732:FLUTA_RS03305
uniprot id: F2IHA2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

755732:FLUTA RS05820
gene id: 755732:FLUTA_RS05820
uniprot id: F2IAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

755732:FLUTA RS20945
gene id: 755732:FLUTA_RS20945
uniprot id: F2IKG5
names: Similarity
messages: Belongs to the SecB family.

755732:FLUTA RS07605
gene id: 755732:FLUTA_RS07605
uniprot id: F2IF35
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

755732:FLUTA RS01080
gene id: 755732:FLUTA_RS01080
uniprot id: F2IBZ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

755732:FLUTA RS06055
gene id: 755732:FLUTA_RS06055
uniprot id: F2IBB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

755732:FLUTA RS07310
gene id: 755732:FLUTA_RS07310
uniprot id: F2IEC7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

755732:FLUTA RS06590
gene id: 755732:FLUTA_RS06590
uniprot id: F2ICT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS00760
gene id: 755732:FLUTA_RS00760
uniprot id: F2IBT4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

755732:FLUTA RS05240
gene id: 755732:FLUTA_RS05240
uniprot id: F2I9Q2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS15875
gene id: 755732:FLUTA_RS15875
uniprot id: F2I9G9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

755732:FLUTA RS07025
gene id: 755732:FLUTA_RS07025
uniprot id: F2IDM1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

755732:FLUTA RS03900
gene id: 755732:FLUTA_RS03900
uniprot id: F2IIS2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

755732:FLUTA RS12340
gene id: 755732:FLUTA_RS12340
uniprot id: F2ID53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

755732:FLUTA RS05755
gene id: 755732:FLUTA_RS05755
uniprot id: F2IAK9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

755732:FLUTA RS00375
gene id: 755732:FLUTA_RS00375
uniprot id: F2IAF2
names: Similarity
messages: Belongs to the Dps family.

755732:FLUTA RS07465
gene id: 755732:FLUTA_RS07465
uniprot id: F2IEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

755732:FLUTA RS16445
gene id: 755732:FLUTA_RS16445
uniprot id: F2IA85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

755732:FLUTA RS10410
gene id: 755732:FLUTA_RS10410
uniprot id: F2I9A9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

755732:FLUTA RS02545
gene id: 755732:FLUTA_RS02545
uniprot id: F2IFQ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

755732:FLUTA RS14425
gene id: 755732:FLUTA_RS14425
uniprot id: F2IID2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

755732:FLUTA RS18110
gene id: 755732:FLUTA_RS18110
uniprot id: F2IE30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

755732:FLUTA RS05710
gene id: 755732:FLUTA_RS05710
uniprot id: F2IAK0
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS20080
gene id: 755732:FLUTA_RS20080
uniprot id: F2IIM5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

755732:FLUTA RS19940
gene id: 755732:FLUTA_RS19940
uniprot id: F2IIJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

755732:FLUTA RS14140
gene id: 755732:FLUTA_RS14140
uniprot id: F2IHM2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

755732:FLUTA RS10445
gene id: 755732:FLUTA_RS10445
uniprot id: F2I9B6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

755732:FLUTA RS07440
gene id: 755732:FLUTA_RS07440
uniprot id: F2IEF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

755732:FLUTA RS11870
gene id: 755732:FLUTA_RS11870
uniprot id: F2ICB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

755732:FLUTA RS12555
gene id: 755732:FLUTA_RS12555
uniprot id: F2IDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS19280
gene id: 755732:FLUTA_RS19280
uniprot id: F2IH13
names: Similarity
messages: Belongs to the AHA1 family.

755732:FLUTA RS03040
gene id: 755732:FLUTA_RS03040
uniprot id: F2IGJ8
names: Similarity
messages: Belongs to the nitroreductase family.

755732:FLUTA RS16385
gene id: 755732:FLUTA_RS16385
uniprot id: F2IA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

755732:FLUTA RS09055
gene id: 755732:FLUTA_RS09055
uniprot id: F2II87
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

755732:FLUTA RS12005
gene id: 755732:FLUTA_RS12005
uniprot id: F2ICD2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

755732:FLUTA RS08545
gene id: 755732:FLUTA_RS08545
uniprot id: F2IGS9
names: Similarity
messages: Belongs to the HsdR family.

755732:FLUTA RS09140
gene id: 755732:FLUTA_RS09140
uniprot id: F2IIA2
names: Similarity
messages: Belongs to the peptidase M1 family.

755732:FLUTA RS11060
gene id: 755732:FLUTA_RS11060
uniprot id: F2IAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

755732:FLUTA RS09790
gene id: 755732:FLUTA_RS09790
uniprot id: F2IJQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS11095
gene id: 755732:FLUTA_RS11095
uniprot id: F2IAP5
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS00650
gene id: 755732:FLUTA_RS00650
uniprot id: F2IB59
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

755732:FLUTA RS12680
gene id: 755732:FLUTA_RS12680
uniprot id: F2IDW9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

755732:FLUTA RS13045
gene id: 755732:FLUTA_RS13045
uniprot id: F2IF99
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS06520
gene id: 755732:FLUTA_RS06520
uniprot id: F2IC69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

755732:FLUTA RS11535
gene id: 755732:FLUTA_RS11535
uniprot id: F2IBI1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS01780
gene id: 755732:FLUTA_RS01780
uniprot id: F2IDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

755732:FLUTA RS04490
gene id: 755732:FLUTA_RS04490
uniprot id: F2IJK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS06145
gene id: 755732:FLUTA_RS06145
uniprot id: F2IBD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

755732:FLUTA RS10310
gene id: 755732:FLUTA_RS10310
uniprot id: F2I989
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

755732:FLUTA RS04230
gene id: 755732:FLUTA_RS04230
uniprot id: F2IJF5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

755732:FLUTA RS09220
gene id: 755732:FLUTA_RS09220
uniprot id: F2IIB9
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS10450
gene id: 755732:FLUTA_RS10450
uniprot id: F2I9B7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

755732:FLUTA RS17035
gene id: 755732:FLUTA_RS17035
uniprot id: F2IBQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS17105
gene id: 755732:FLUTA_RS17105
uniprot id: F2IBR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

755732:FLUTA RS11830
gene id: 755732:FLUTA_RS11830
uniprot id: F2ICA2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

755732:FLUTA RS07225
gene id: 755732:FLUTA_RS07225
uniprot id: F2IEB0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

755732:FLUTA RS11890
gene id: 755732:FLUTA_RS11890
uniprot id: F2ICB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

755732:FLUTA RS19155
gene id: 755732:FLUTA_RS19155
uniprot id: F2IGD5
names: Similarity
messages: Belongs to the CarB family.

755732:FLUTA RS03410
gene id: 755732:FLUTA_RS03410
uniprot id: F2IHC3
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS04820
gene id: 755732:FLUTA_RS04820
uniprot id: F2IK64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

755732:FLUTA RS16960
gene id: 755732:FLUTA_RS16960
uniprot id: F2IBN8
names: Similarity
messages: Belongs to the peptidase S9A family.

755732:FLUTA RS10385
gene id: 755732:FLUTA_RS10385
uniprot id: F2I9A4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

755732:FLUTA RS07330
gene id: 755732:FLUTA_RS07330
uniprot id: F2IED1
names: Similarity
messages: Belongs to the RecJ family.

755732:FLUTA RS06655
gene id: 755732:FLUTA_RS06655
uniprot id: F2ICU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

755732:FLUTA RS17230
gene id: 755732:FLUTA_RS17230
uniprot id: F2ICE9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

755732:FLUTA RS06135
gene id: 755732:FLUTA_RS06135
uniprot id: F2IBD1
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS00025
gene id: 755732:FLUTA_RS00025
uniprot id: F2I9M4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

755732:FLUTA RS08050
gene id: 755732:FLUTA_RS08050
uniprot id: F2IFX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS14950
gene id: 755732:FLUTA_RS14950
uniprot id: F2IJ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

755732:FLUTA RS09050
gene id: 755732:FLUTA_RS09050
uniprot id: F2II86
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

755732:FLUTA RS04095
gene id: 755732:FLUTA_RS04095
uniprot id: F2IIW1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

755732:FLUTA RS15640
gene id: 755732:FLUTA_RS15640
uniprot id: F2IKH8
names: Similarity
messages: Belongs to the DEAD box helicase family.

755732:FLUTA RS05870
gene id: 755732:FLUTA_RS05870
uniprot id: F2IB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

755732:FLUTA RS06280
gene id: 755732:FLUTA_RS06280
uniprot id: F2IC21
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

755732:FLUTA RS17740
gene id: 755732:FLUTA_RS17740
uniprot id: F2IDA7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

755732:FLUTA RS05145
gene id: 755732:FLUTA_RS05145
uniprot id: F2I980
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS00225
gene id: 755732:FLUTA_RS00225
uniprot id: F2IAC2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

755732:FLUTA RS09800
gene id: 755732:FLUTA_RS09800
uniprot id: F2IJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

755732:FLUTA RS17190
gene id: 755732:FLUTA_RS17190
uniprot id: F2ICE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

755732:FLUTA RS08885
gene id: 755732:FLUTA_RS08885
uniprot id: F2IHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

755732:FLUTA RS07370
gene id: 755732:FLUTA_RS07370
uniprot id: F2IED9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

755732:FLUTA RS14230
gene id: 755732:FLUTA_RS14230
uniprot id: F2IHP1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

755732:FLUTA RS00150
gene id: 755732:FLUTA_RS00150
uniprot id: F2IAA7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS09985
gene id: 755732:FLUTA_RS09985
uniprot id: F2IK79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

755732:FLUTA RS15910
gene id: 755732:FLUTA_RS15910
uniprot id: F2I9H6
names: Cofactor
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

755732:FLUTA RS04850
gene id: 755732:FLUTA_RS04850
uniprot id: F2IK70
names: Subcellular Location Annotation
messages: Mitochondrion

755732:FLUTA RS01025
gene id: 755732:FLUTA_RS01025
uniprot id: F2IBY8
names: Subcellular Location Annotation
messages: Membrane

755732:FLUTA RS05330
gene id: 755732:FLUTA_RS05330
uniprot id: F2I9S0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

755732:FLUTA RS12405
gene id: 755732:FLUTA_RS12405
uniprot id: F2IDR8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

755732:FLUTA RS17020
gene id: 755732:FLUTA_RS17020
uniprot id: F2IBQ0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

755732:FLUTA RS12575
gene id: 755732:FLUTA_RS12575
uniprot id: F2IDU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

755732:FLUTA RS10095
gene id: 755732:FLUTA_RS10095
uniprot id: F2IKA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

755732:FLUTA RS11415
gene id: 755732:FLUTA_RS11415
uniprot id: F2IBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

755732:FLUTA RS06755
gene id: 755732:FLUTA_RS06755
uniprot id: F2ICW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

755732:FLUTA RS07395
gene id: 755732:FLUTA_RS07395
uniprot id: F2IEE4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

755732:FLUTA RS14760
gene id: 755732:FLUTA_RS14760
uniprot id: F2IJ55
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

755732:FLUTA RS19460
gene id: 755732:FLUTA_RS19460
uniprot id: F2IH49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

755732:FLUTA RS12505
gene id: 755732:FLUTA_RS12505
uniprot id: F2IDT8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

755732:FLUTA RS20070
gene id: 755732:FLUTA_RS20070
uniprot id: F2IIM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

755732:FLUTA RS14640
gene id: 755732:FLUTA_RS14640
uniprot id: F2IIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

755732:FLUTA RS12220
gene id: 755732:FLUTA_RS12220
uniprot id: F2ID28
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

755732:FLUTA RS07890
gene id: 755732:FLUTA_RS07890
uniprot id: F2IF91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.