746697:AEQSU RS11210
gene id: 746697:AEQSU_RS11210
uniprot id: I3YXL0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

746697:AEQSU RS11725
gene id: 746697:AEQSU_RS11725
uniprot id: I3YXV6
names: Similarity
messages: Belongs to the arginase family.

746697:AEQSU RS00650
gene id: 746697:AEQSU_RS00650
uniprot id: I3YRP2
names: Cofactor
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

746697:AEQSU RS14310
gene id: 746697:AEQSU_RS14310
uniprot id: I3YZB9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

746697:AEQSU RS02865
gene id: 746697:AEQSU_RS02865
uniprot id: I3YSX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS05905
gene id: 746697:AEQSU_RS05905
uniprot id: I3YUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

746697:AEQSU RS00230
gene id: 746697:AEQSU_RS00230
uniprot id: I3YRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

746697:AEQSU RS00760
gene id: 746697:AEQSU_RS00760
uniprot id: I3YRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

746697:AEQSU RS06750
gene id: 746697:AEQSU_RS06750
uniprot id: I3YV39
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS13000
gene id: 746697:AEQSU_RS13000
uniprot id: I3YYL4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

746697:AEQSU RS12810
gene id: 746697:AEQSU_RS12810
uniprot id: I3YYH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS11940
gene id: 746697:AEQSU_RS11940
uniprot id: I3YY00
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

746697:AEQSU RS01985
gene id: 746697:AEQSU_RS01985
uniprot id: I3YSF1
names: Function
messages: May be involved in the biogenesis of curli organelles.

746697:AEQSU RS05265
gene id: 746697:AEQSU_RS05265
uniprot id: I3YU95
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06095
gene id: 746697:AEQSU_RS06095
uniprot id: I3YUQ8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

746697:AEQSU RS09210
gene id: 746697:AEQSU_RS09210
uniprot id: I3YWG8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

746697:AEQSU RS10835
gene id: 746697:AEQSU_RS10835
uniprot id: I3YXD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

746697:AEQSU RS12265
gene id: 746697:AEQSU_RS12265
uniprot id: I3YY69
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

746697:AEQSU RS00730
gene id: 746697:AEQSU_RS00730
uniprot id: I3YRQ9
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS07385
gene id: 746697:AEQSU_RS07385
uniprot id: I3YVG4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

746697:AEQSU RS05800
gene id: 746697:AEQSU_RS05800
uniprot id: I3YUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

746697:AEQSU RS11890
gene id: 746697:AEQSU_RS11890
uniprot id: I3YXY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

746697:AEQSU RS14365
gene id: 746697:AEQSU_RS14365
uniprot id: I3YZD0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

746697:AEQSU RS09325
gene id: 746697:AEQSU_RS09325
uniprot id: I3YWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

746697:AEQSU RS10105
gene id: 746697:AEQSU_RS10105
uniprot id: I3YWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS13500
gene id: 746697:AEQSU_RS13500
uniprot id: I3YYW6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

746697:AEQSU RS06055
gene id: 746697:AEQSU_RS06055
uniprot id: I3YUQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

746697:AEQSU RS03060
gene id: 746697:AEQSU_RS03060
uniprot id: I3YT16
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

746697:AEQSU RS14965
gene id: 746697:AEQSU_RS14965
uniprot id: I3YZP5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

746697:AEQSU RS02145
gene id: 746697:AEQSU_RS02145
uniprot id: I3YSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

746697:AEQSU RS04010
gene id: 746697:AEQSU_RS04010
uniprot id: I3YTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

746697:AEQSU RS05440
gene id: 746697:AEQSU_RS05440
uniprot id: I3YUC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

746697:AEQSU RS10135
gene id: 746697:AEQSU_RS10135
uniprot id: I3YWZ6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

746697:AEQSU RS01540
gene id: 746697:AEQSU_RS01540
uniprot id: I3YS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

746697:AEQSU RS04365
gene id: 746697:AEQSU_RS04365
uniprot id: I3YTS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

746697:AEQSU RS00790
gene id: 746697:AEQSU_RS00790
uniprot id: I3YRS1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS05070
gene id: 746697:AEQSU_RS05070
uniprot id: I3YU56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

746697:AEQSU RS08125
gene id: 746697:AEQSU_RS08125
uniprot id: I3YVW0
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

746697:AEQSU RS04135
gene id: 746697:AEQSU_RS04135
uniprot id: I3YTM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

746697:AEQSU RS02430
gene id: 746697:AEQSU_RS02430
uniprot id: I3YSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

746697:AEQSU RS02040
gene id: 746697:AEQSU_RS02040
uniprot id: I3YSG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

746697:AEQSU RS07095
gene id: 746697:AEQSU_RS07095
uniprot id: I3YVA8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

746697:AEQSU RS07080
gene id: 746697:AEQSU_RS07080
uniprot id: I3YVA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS05325
gene id: 746697:AEQSU_RS05325
uniprot id: I3YUA6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09230
gene id: 746697:AEQSU_RS09230
uniprot id: I3YWH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

746697:AEQSU RS09475
gene id: 746697:AEQSU_RS09475
uniprot id: I3YWM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

746697:AEQSU RS01535
gene id: 746697:AEQSU_RS01535
uniprot id: I3YS63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

746697:AEQSU RS05350
gene id: 746697:AEQSU_RS05350
uniprot id: I3YUB1
names: Similarity
messages: Belongs to the pyruvate kinase family.

746697:AEQSU RS02100
gene id: 746697:AEQSU_RS02100
uniprot id: I3YSH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS04605
gene id: 746697:AEQSU_RS04605
uniprot id: I3YTX0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

746697:AEQSU RS05220
gene id: 746697:AEQSU_RS05220
uniprot id: I3YU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

746697:AEQSU RS13465
gene id: 746697:AEQSU_RS13465
uniprot id: I3YYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

746697:AEQSU RS03980
gene id: 746697:AEQSU_RS03980
uniprot id: I3YTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

746697:AEQSU RS12755
gene id: 746697:AEQSU_RS12755
uniprot id: I3YYG5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

746697:AEQSU RS03565
gene id: 746697:AEQSU_RS03565
uniprot id: I3YTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

746697:AEQSU RS11755
gene id: 746697:AEQSU_RS11755
uniprot id: I3YXW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09290
gene id: 746697:AEQSU_RS09290
uniprot id: I3YWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS14030
gene id: 746697:AEQSU_RS14030
uniprot id: I3YZ69
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

746697:AEQSU RS05695
gene id: 746697:AEQSU_RS05695
uniprot id: I3YUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

746697:AEQSU RS04780
gene id: 746697:AEQSU_RS04780
uniprot id: I3YU02
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

746697:AEQSU RS01925
gene id: 746697:AEQSU_RS01925
uniprot id: I3YSD9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS11830
gene id: 746697:AEQSU_RS11830
uniprot id: I3YXX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS02705
gene id: 746697:AEQSU_RS02705
uniprot id: I3YSU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS07715
gene id: 746697:AEQSU_RS07715
uniprot id: I3YVM8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

746697:AEQSU RS05135
gene id: 746697:AEQSU_RS05135
uniprot id: I3YU69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS02290
gene id: 746697:AEQSU_RS02290
uniprot id: I3YSL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09455
gene id: 746697:AEQSU_RS09455
uniprot id: I3YWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

746697:AEQSU RS06285
gene id: 746697:AEQSU_RS06285
uniprot id: I3YUU5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

746697:AEQSU RS02905
gene id: 746697:AEQSU_RS02905
uniprot id: I3YSY6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07255
gene id: 746697:AEQSU_RS07255
uniprot id: I3YVD9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

746697:AEQSU RS15680
gene id: 746697:AEQSU_RS15680
uniprot id: I3Z041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS13010
gene id: 746697:AEQSU_RS13010
uniprot id: I3YYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

746697:AEQSU RS08550
gene id: 746697:AEQSU_RS08550
uniprot id: I3YW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS06305
gene id: 746697:AEQSU_RS06305
uniprot id: I3YUU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS00665
gene id: 746697:AEQSU_RS00665
uniprot id: I3YRP5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

746697:AEQSU RS02590
gene id: 746697:AEQSU_RS02590
uniprot id: I3YSS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

746697:AEQSU RS02750
gene id: 746697:AEQSU_RS02750
uniprot id: I3YSV7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

746697:AEQSU RS06235
gene id: 746697:AEQSU_RS06235
uniprot id: I3YUT5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS13075
gene id: 746697:AEQSU_RS13075
uniprot id: I3YYM9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

746697:AEQSU RS14185
gene id: 746697:AEQSU_RS14185
uniprot id: I3YZ94
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

746697:AEQSU RS03955
gene id: 746697:AEQSU_RS03955
uniprot id: I3YTJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

746697:AEQSU RS01375
gene id: 746697:AEQSU_RS01375
uniprot id: I3YS32
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS14850
gene id: 746697:AEQSU_RS14850
uniprot id: I3YZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

746697:AEQSU RS01890
gene id: 746697:AEQSU_RS01890
uniprot id: I3YSD2
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS02625
gene id: 746697:AEQSU_RS02625
uniprot id: I3YST1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS02200
gene id: 746697:AEQSU_RS02200
uniprot id: I3YSJ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

746697:AEQSU RS09600
gene id: 746697:AEQSU_RS09600
uniprot id: I3YWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

746697:AEQSU RS07765
gene id: 746697:AEQSU_RS07765
uniprot id: I3YVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS10000
gene id: 746697:AEQSU_RS10000
uniprot id: I3YWW9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

746697:AEQSU RS04275
gene id: 746697:AEQSU_RS04275
uniprot id: U3GJL8
names: Similarity
messages: Belongs to the SCO1/2 family.

746697:AEQSU RS02010
gene id: 746697:AEQSU_RS02010
uniprot id: I3YSF7
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09570
gene id: 746697:AEQSU_RS09570
uniprot id: I3YWP0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

746697:AEQSU RS00275
gene id: 746697:AEQSU_RS00275
uniprot id: I3YRH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

746697:AEQSU RS02225
gene id: 746697:AEQSU_RS02225
uniprot id: I3YSK0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS09115
gene id: 746697:AEQSU_RS09115
uniprot id: I3YWF0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

746697:AEQSU RS05400
gene id: 746697:AEQSU_RS05400
uniprot id: I3YUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS07825
gene id: 746697:AEQSU_RS07825
uniprot id: I3YVQ0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS10570
gene id: 746697:AEQSU_RS10570
uniprot id: I3YX81
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

746697:AEQSU RS14770
gene id: 746697:AEQSU_RS14770
uniprot id: I3YZK8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

746697:AEQSU RS08540
gene id: 746697:AEQSU_RS08540
uniprot id: I3YW37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

746697:AEQSU RS00105
gene id: 746697:AEQSU_RS00105
uniprot id: I3YRD6
names: Similarity
messages: Belongs to the glutamate synthase family.

746697:AEQSU RS13080
gene id: 746697:AEQSU_RS13080
uniprot id: I3YYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

746697:AEQSU RS05920
gene id: 746697:AEQSU_RS05920
uniprot id: I3YUM4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09240
gene id: 746697:AEQSU_RS09240
uniprot id: I3YWH4
names: Similarity
messages: Belongs to the NAD synthetase family.

746697:AEQSU RS07895
gene id: 746697:AEQSU_RS07895
uniprot id: I3YVR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

746697:AEQSU RS13130
gene id: 746697:AEQSU_RS13130
uniprot id: I3YYP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

746697:AEQSU RS02090
gene id: 746697:AEQSU_RS02090
uniprot id: I3YSH3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

746697:AEQSU RS02820
gene id: 746697:AEQSU_RS02820
uniprot id: I3YSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

746697:AEQSU RS14895
gene id: 746697:AEQSU_RS14895
uniprot id: I3YZN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

746697:AEQSU RS01135
gene id: 746697:AEQSU_RS01135
uniprot id: I3YRZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

746697:AEQSU RS04760
gene id: 746697:AEQSU_RS04760
uniprot id: I3YTZ8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

746697:AEQSU RS10830
gene id: 746697:AEQSU_RS10830
uniprot id: I3YXD2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

746697:AEQSU RS10645
gene id: 746697:AEQSU_RS10645
uniprot id: I3YX95
names: Similarity
messages: Belongs to the MQO family.

746697:AEQSU RS09525
gene id: 746697:AEQSU_RS09525
uniprot id: I3YWN0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

746697:AEQSU RS07900
gene id: 746697:AEQSU_RS07900
uniprot id: I3YVR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

746697:AEQSU RS14860
gene id: 746697:AEQSU_RS14860
uniprot id: I3YZM6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

746697:AEQSU RS00380
gene id: 746697:AEQSU_RS00380
uniprot id: I3YRJ0
names: Similarity
messages: Belongs to the RelE toxin family.

746697:AEQSU RS07795
gene id: 746697:AEQSU_RS07795
uniprot id: I3YVP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS04860
gene id: 746697:AEQSU_RS04860
uniprot id: I3YU18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

746697:AEQSU RS02005
gene id: 746697:AEQSU_RS02005
uniprot id: I3YSF6
names: Similarity
messages: Belongs to the glutamine synthetase family.

746697:AEQSU RS15930
gene id: 746697:AEQSU_RS15930
uniprot id: I3Z089
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

746697:AEQSU RS07730
gene id: 746697:AEQSU_RS07730
uniprot id: I3YVN1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

746697:AEQSU RS05565
gene id: 746697:AEQSU_RS05565
uniprot id: U3GJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

746697:AEQSU RS01740
gene id: 746697:AEQSU_RS01740
uniprot id: I3YSA3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

746697:AEQSU RS11290
gene id: 746697:AEQSU_RS11290
uniprot id: I3YXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

746697:AEQSU RS14460
gene id: 746697:AEQSU_RS14460
uniprot id: I3YZE9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

746697:AEQSU RS09855
gene id: 746697:AEQSU_RS09855
uniprot id: I3YWU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS01165
gene id: 746697:AEQSU_RS01165
uniprot id: I3YRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS06555
gene id: 746697:AEQSU_RS06555
uniprot id: I3YUZ9
names: Similarity
messages: Belongs to the peptidase M4 family.

746697:AEQSU RS15000
gene id: 746697:AEQSU_RS15000
uniprot id: I3YZQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

746697:AEQSU RS11765
gene id: 746697:AEQSU_RS11765
uniprot id: I3YXW4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

746697:AEQSU RS09295
gene id: 746697:AEQSU_RS09295
uniprot id: I3YWI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

746697:AEQSU RS09535
gene id: 746697:AEQSU_RS09535
uniprot id: I3YWN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

746697:AEQSU RS07700
gene id: 746697:AEQSU_RS07700
uniprot id: I3YVM5
names: Similarity
messages: Belongs to the ArsC family.

746697:AEQSU RS14105
gene id: 746697:AEQSU_RS14105
uniprot id: I3YZ84
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS03200
gene id: 746697:AEQSU_RS03200
uniprot id: I3YT46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS09505
gene id: 746697:AEQSU_RS09505
uniprot id: I3YWM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

746697:AEQSU RS09630
gene id: 746697:AEQSU_RS09630
uniprot id: I3YWQ1
names: Similarity
messages: Belongs to the peptidase C40 family.

746697:AEQSU RS00615
gene id: 746697:AEQSU_RS00615
uniprot id: I3YRN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

746697:AEQSU RS13940
gene id: 746697:AEQSU_RS13940
uniprot id: I3YZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

746697:AEQSU RS10575
gene id: 746697:AEQSU_RS10575
uniprot id: I3YX82
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

746697:AEQSU RS13015
gene id: 746697:AEQSU_RS13015
uniprot id: I3YYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

746697:AEQSU RS14825
gene id: 746697:AEQSU_RS14825
uniprot id: I3YZL9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

746697:AEQSU RS06820
gene id: 746697:AEQSU_RS06820
uniprot id: I3YV53
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

746697:AEQSU RS06180
gene id: 746697:AEQSU_RS06180
uniprot id: I3YUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

746697:AEQSU RS02450
gene id: 746697:AEQSU_RS02450
uniprot id: I3YSP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

746697:AEQSU RS06770
gene id: 746697:AEQSU_RS06770
uniprot id: I3YV43
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

746697:AEQSU RS01500
gene id: 746697:AEQSU_RS01500
uniprot id: I3YS55
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

746697:AEQSU RS12270
gene id: 746697:AEQSU_RS12270
uniprot id: I3YY70
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09700
gene id: 746697:AEQSU_RS09700
uniprot id: I3YWR5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS12385
gene id: 746697:AEQSU_RS12385
uniprot id: I3YY93
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS05535
gene id: 746697:AEQSU_RS05535
uniprot id: I3YUE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

746697:AEQSU RS02975
gene id: 746697:AEQSU_RS02975
uniprot id: I3YSZ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS12340
gene id: 746697:AEQSU_RS12340
uniprot id: I3YY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

746697:AEQSU RS12960
gene id: 746697:AEQSU_RS12960
uniprot id: I3YYK6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

746697:AEQSU RS00500
gene id: 746697:AEQSU_RS00500
uniprot id: I3YRL3
names: Similarity
messages: Belongs to the peptidase M16 family.

746697:AEQSU RS09995
gene id: 746697:AEQSU_RS09995
uniprot id: I3YWW8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

746697:AEQSU RS05910
gene id: 746697:AEQSU_RS05910
uniprot id: I3YUM2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

746697:AEQSU RS04905
gene id: 746697:AEQSU_RS04905
uniprot id: I3YU27
names: Similarity
messages: Belongs to the peptidase S41A family.

746697:AEQSU RS00480
gene id: 746697:AEQSU_RS00480
uniprot id: I3YRK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS11975
gene id: 746697:AEQSU_RS11975
uniprot id: I3YY07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS00755
gene id: 746697:AEQSU_RS00755
uniprot id: I3YRR4
names: Similarity
messages: Belongs to the thioredoxin family.

746697:AEQSU RS09880
gene id: 746697:AEQSU_RS09880
uniprot id: I3YWV0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

746697:AEQSU RS02725
gene id: 746697:AEQSU_RS02725
uniprot id: I3YSV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS13050
gene id: 746697:AEQSU_RS13050
uniprot id: I3YYM4
names: Similarity
messages: Belongs to the peptidase C56 family.

746697:AEQSU RS00160
gene id: 746697:AEQSU_RS00160
uniprot id: I3YRE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

746697:AEQSU RS07475
gene id: 746697:AEQSU_RS07475
uniprot id: I3YVI1
names: Similarity
messages: Belongs to the SufE family.

746697:AEQSU RS07065
gene id: 746697:AEQSU_RS07065
uniprot id: I3YVA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS10765
gene id: 746697:AEQSU_RS10765
uniprot id: I3YXB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS01335
gene id: 746697:AEQSU_RS01335
uniprot id: I3YS25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

746697:AEQSU RS03085
gene id: 746697:AEQSU_RS03085
uniprot id: I3YT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS01400
gene id: 746697:AEQSU_RS01400
uniprot id: I3YS37
names: Similarity
messages: Belongs to the HSP15 family.

746697:AEQSU RS02520
gene id: 746697:AEQSU_RS02520
uniprot id: I3YSR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

746697:AEQSU RS07200
gene id: 746697:AEQSU_RS07200
uniprot id: I3YVC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

746697:AEQSU RS00100
gene id: 746697:AEQSU_RS00100
uniprot id: I3YRD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

746697:AEQSU RS01620
gene id: 746697:AEQSU_RS01620
uniprot id: I3YS80
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

746697:AEQSU RS11655
gene id: 746697:AEQSU_RS11655
uniprot id: I3YXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

746697:AEQSU RS01570
gene id: 746697:AEQSU_RS01570
uniprot id: I3YS70
names: Subcellular Location Annotation
messages: Nucleus

746697:AEQSU RS11730
gene id: 746697:AEQSU_RS11730
uniprot id: I3YXV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

746697:AEQSU RS14595
gene id: 746697:AEQSU_RS14595
uniprot id: I3YZH4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

746697:AEQSU RS12060
gene id: 746697:AEQSU_RS12060
uniprot id: I3YY25
names: Similarity
messages: Belongs to the phosphohexose mutase family.

746697:AEQSU RS07815
gene id: 746697:AEQSU_RS07815
uniprot id: I3YVP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

746697:AEQSU RS02810
gene id: 746697:AEQSU_RS02810
uniprot id: I3YSW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS08825
gene id: 746697:AEQSU_RS08825
uniprot id: I3YW93
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

746697:AEQSU RS12555
gene id: 746697:AEQSU_RS12555
uniprot id: I3YYC7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

746697:AEQSU RS10895
gene id: 746697:AEQSU_RS10895
uniprot id: I3YXE6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

746697:AEQSU RS00165
gene id: 746697:AEQSU_RS00165
uniprot id: I3YRE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

746697:AEQSU RS02580
gene id: 746697:AEQSU_RS02580
uniprot id: I3YSS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09510
gene id: 746697:AEQSU_RS09510
uniprot id: I3YWM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

746697:AEQSU RS09935
gene id: 746697:AEQSU_RS09935
uniprot id: I3YWV6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

746697:AEQSU RS09785
gene id: 746697:AEQSU_RS09785
uniprot id: I3YWT2
names: Similarity
messages: Belongs to the UPF0246 family.

746697:AEQSU RS14150
gene id: 746697:AEQSU_RS14150
uniprot id: I3YZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS08860
gene id: 746697:AEQSU_RS08860
uniprot id: I3YWA0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

746697:AEQSU RS05320
gene id: 746697:AEQSU_RS05320
uniprot id: I3YUA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

746697:AEQSU RS02720
gene id: 746697:AEQSU_RS02720
uniprot id: I3YSV1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

746697:AEQSU RS07485
gene id: 746697:AEQSU_RS07485
uniprot id: I3YVI3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

746697:AEQSU RS06865
gene id: 746697:AEQSU_RS06865
uniprot id: I3YV62
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS01340
gene id: 746697:AEQSU_RS01340
uniprot id: I3YS26
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

746697:AEQSU RS00185
gene id: 746697:AEQSU_RS00185
uniprot id: I3YRF2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

746697:AEQSU RS00470
gene id: 746697:AEQSU_RS00470
uniprot id: I3YRK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

746697:AEQSU RS00530
gene id: 746697:AEQSU_RS00530
uniprot id: I3YRL8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS10840
gene id: 746697:AEQSU_RS10840
uniprot id: I3YXD4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

746697:AEQSU RS00795
gene id: 746697:AEQSU_RS00795
uniprot id: I3YRS2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

746697:AEQSU RS07215
gene id: 746697:AEQSU_RS07215
uniprot id: I3YVD1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

746697:AEQSU RS09490
gene id: 746697:AEQSU_RS09490
uniprot id: I3YWM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

746697:AEQSU RS04230
gene id: 746697:AEQSU_RS04230
uniprot id: I3YTP5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS05305
gene id: 746697:AEQSU_RS05305
uniprot id: I3YUA2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

746697:AEQSU RS16005
gene id: 746697:AEQSU_RS16005
uniprot id: I3Z0A3
names: Similarity
messages: Belongs to the IMPACT family.

746697:AEQSU RS04125
gene id: 746697:AEQSU_RS04125
uniprot id: I3YTM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS08640
gene id: 746697:AEQSU_RS08640
uniprot id: I3YW57
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

746697:AEQSU RS15095
gene id: 746697:AEQSU_RS15095
uniprot id: I3YZS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

746697:AEQSU RS04390
gene id: 746697:AEQSU_RS04390
uniprot id: I3YTS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

746697:AEQSU RS06340
gene id: 746697:AEQSU_RS06340
uniprot id: I3YUV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS06445
gene id: 746697:AEQSU_RS06445
uniprot id: I3YUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

746697:AEQSU RS02555
gene id: 746697:AEQSU_RS02555
uniprot id: I3YSR8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

746697:AEQSU RS03820
gene id: 746697:AEQSU_RS03820
uniprot id: I3YTG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS01025
gene id: 746697:AEQSU_RS01025
uniprot id: I3YRW8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

746697:AEQSU RS12375
gene id: 746697:AEQSU_RS12375
uniprot id: I3YY91
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

746697:AEQSU RS03455
gene id: 746697:AEQSU_RS03455
uniprot id: I3YT98
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

746697:AEQSU RS02530
gene id: 746697:AEQSU_RS02530
uniprot id: I3YSR3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

746697:AEQSU RS11185
gene id: 746697:AEQSU_RS11185
uniprot id: I3YXK5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

746697:AEQSU RS05805
gene id: 746697:AEQSU_RS05805
uniprot id: I3YUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

746697:AEQSU RS08650
gene id: 746697:AEQSU_RS08650
uniprot id: I3YW59
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS12570
gene id: 746697:AEQSU_RS12570
uniprot id: I3YYD0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

746697:AEQSU RS08780
gene id: 746697:AEQSU_RS08780
uniprot id: I3YW84
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

746697:AEQSU RS04355
gene id: 746697:AEQSU_RS04355
uniprot id: I3YTS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

746697:AEQSU RS09560
gene id: 746697:AEQSU_RS09560
uniprot id: I3YWN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

746697:AEQSU RS11600
gene id: 746697:AEQSU_RS11600
uniprot id: I3YXT1
names: Similarity
messages: Belongs to the glutamate synthase family.

746697:AEQSU RS15125
gene id: 746697:AEQSU_RS15125
uniprot id: I3YZS7
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS08840
gene id: 746697:AEQSU_RS08840
uniprot id: I3YW96
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

746697:AEQSU RS03985
gene id: 746697:AEQSU_RS03985
uniprot id: I3YTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

746697:AEQSU RS04490
gene id: 746697:AEQSU_RS04490
uniprot id: I3YTU7
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04785
gene id: 746697:AEQSU_RS04785
uniprot id: I3YU03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

746697:AEQSU RS14970
gene id: 746697:AEQSU_RS14970
uniprot id: I3YZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS15150
gene id: 746697:AEQSU_RS15150
uniprot id: I3YZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

746697:AEQSU RS05340
gene id: 746697:AEQSU_RS05340
uniprot id: I3YUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

746697:AEQSU RS05110
gene id: 746697:AEQSU_RS05110
uniprot id: I3YU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS00045
gene id: 746697:AEQSU_RS00045
uniprot id: I3YRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

746697:AEQSU RS04115
gene id: 746697:AEQSU_RS04115
uniprot id: I3YTM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS11420
gene id: 746697:AEQSU_RS11420
uniprot id: I3YXP9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

746697:AEQSU RS15955
gene id: 746697:AEQSU_RS15955
uniprot id: I3Z094
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

746697:AEQSU RS04925
gene id: 746697:AEQSU_RS04925
uniprot id: I3YU31
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS15400
gene id: 746697:AEQSU_RS15400
uniprot id: I3YZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

746697:AEQSU RS15385
gene id: 746697:AEQSU_RS15385
uniprot id: I3YZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS12525
gene id: 746697:AEQSU_RS12525
uniprot id: I3YYC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS08360
gene id: 746697:AEQSU_RS08360
uniprot id: I3YW02
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

746697:AEQSU RS08695
gene id: 746697:AEQSU_RS08695
uniprot id: I3YW68
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

746697:AEQSU RS15190
gene id: 746697:AEQSU_RS15190
uniprot id: I3YZU0
names: Similarity
messages: Belongs to the nitroreductase family.

746697:AEQSU RS06150
gene id: 746697:AEQSU_RS06150
uniprot id: I3YUR8
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06250
gene id: 746697:AEQSU_RS06250
uniprot id: I3YUT9
names: Similarity
messages: Belongs to the peptidase M13 family.

746697:AEQSU RS11430
gene id: 746697:AEQSU_RS11430
uniprot id: I3YXQ0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

746697:AEQSU RS09930
gene id: 746697:AEQSU_RS09930
uniprot id: I3YWV5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

746697:AEQSU RS09915
gene id: 746697:AEQSU_RS09915
uniprot id: I3YWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

746697:AEQSU RS13445
gene id: 746697:AEQSU_RS13445
uniprot id: I3YYV4
names: Similarity
messages: Belongs to the SUI1 family.

746697:AEQSU RS10820
gene id: 746697:AEQSU_RS10820
uniprot id: I3YXD0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

746697:AEQSU RS09815
gene id: 746697:AEQSU_RS09815
uniprot id: I3YWT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

746697:AEQSU RS14640
gene id: 746697:AEQSU_RS14640
uniprot id: I3YZI3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

746697:AEQSU RS03050
gene id: 746697:AEQSU_RS03050
uniprot id: I3YT14
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

746697:AEQSU RS05195
gene id: 746697:AEQSU_RS05195
uniprot id: I3YU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

746697:AEQSU RS11880
gene id: 746697:AEQSU_RS11880
uniprot id: I3YXY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

746697:AEQSU RS09955
gene id: 746697:AEQSU_RS09955
uniprot id: I3YWW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

746697:AEQSU RS02965
gene id: 746697:AEQSU_RS02965
uniprot id: I3YSZ7
names: Similarity
messages: Belongs to the DEAD box helicase family.

746697:AEQSU RS03995
gene id: 746697:AEQSU_RS03995
uniprot id: I3YTJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

746697:AEQSU RS06145
gene id: 746697:AEQSU_RS06145
uniprot id: I3YUR7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

746697:AEQSU RS12980
gene id: 746697:AEQSU_RS12980
uniprot id: I3YYL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

746697:AEQSU RS02685
gene id: 746697:AEQSU_RS02685
uniprot id: I3YSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

746697:AEQSU RS13990
gene id: 746697:AEQSU_RS13990
uniprot id: I3YZ61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

746697:AEQSU RS05525
gene id: 746697:AEQSU_RS05525
uniprot id: I3YUE6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07145
gene id: 746697:AEQSU_RS07145
uniprot id: I3YVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

746697:AEQSU RS01970
gene id: 746697:AEQSU_RS01970
uniprot id: I3YSE8
names: Similarity
messages: Belongs to the AIR synthase family.

746697:AEQSU RS10650
gene id: 746697:AEQSU_RS10650
uniprot id: I3YX96
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

746697:AEQSU RS14035
gene id: 746697:AEQSU_RS14035
uniprot id: I3YZ70
names: Similarity
messages: Belongs to the ClpA/ClpB family.

746697:AEQSU RS14285
gene id: 746697:AEQSU_RS14285
uniprot id: I3YZB4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

746697:AEQSU RS13175
gene id: 746697:AEQSU_RS13175
uniprot id: I3YYP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

746697:AEQSU RS05295
gene id: 746697:AEQSU_RS05295
uniprot id: I3YUA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS04080
gene id: 746697:AEQSU_RS04080
uniprot id: I3YTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

746697:AEQSU RS09540
gene id: 746697:AEQSU_RS09540
uniprot id: I3YWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

746697:AEQSU RS02900
gene id: 746697:AEQSU_RS02900
uniprot id: I3YSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

746697:AEQSU RS15005
gene id: 746697:AEQSU_RS15005
uniprot id: I3YZQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

746697:AEQSU RS12720
gene id: 746697:AEQSU_RS12720
uniprot id: I3YYF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

746697:AEQSU RS03470
gene id: 746697:AEQSU_RS03470
uniprot id: I3YTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS03465
gene id: 746697:AEQSU_RS03465
uniprot id: I3YTA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

746697:AEQSU RS07570
gene id: 746697:AEQSU_RS07570
uniprot id: I3YVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS07050
gene id: 746697:AEQSU_RS07050
uniprot id: I3YV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

746697:AEQSU RS07540
gene id: 746697:AEQSU_RS07540
uniprot id: I3YVJ4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

746697:AEQSU RS09480
gene id: 746697:AEQSU_RS09480
uniprot id: I3YWM1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

746697:AEQSU RS14485
gene id: 746697:AEQSU_RS14485
uniprot id: I3YZF3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

746697:AEQSU RS02550
gene id: 746697:AEQSU_RS02550
uniprot id: I3YSR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS02325
gene id: 746697:AEQSU_RS02325
uniprot id: I3YSM1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS15890
gene id: 746697:AEQSU_RS15890
uniprot id: I3Z081
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

746697:AEQSU RS03860
gene id: 746697:AEQSU_RS03860
uniprot id: I3YTH4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06170
gene id: 746697:AEQSU_RS06170
uniprot id: I3YUS2
names: Similarity
messages: Belongs to the peptidase S41A family.

746697:AEQSU RS14725
gene id: 746697:AEQSU_RS14725
uniprot id: I3YZJ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

746697:AEQSU RS09300
gene id: 746697:AEQSU_RS09300
uniprot id: I3YWI6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS08405
gene id: 746697:AEQSU_RS08405
uniprot id: I3YW11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

746697:AEQSU RS06470
gene id: 746697:AEQSU_RS06470
uniprot id: I3YUY3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

746697:AEQSU RS06680
gene id: 746697:AEQSU_RS06680
uniprot id: I3YV24
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS00600
gene id: 746697:AEQSU_RS00600
uniprot id: I3YRN3
names: Subcellular Location Annotation
messages: Cytoplasm

746697:AEQSU RS06030
gene id: 746697:AEQSU_RS06030
uniprot id: I3YUP6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

746697:AEQSU RS01065
gene id: 746697:AEQSU_RS01065
uniprot id: I3YRX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

746697:AEQSU RS04790
gene id: 746697:AEQSU_RS04790
uniprot id: I3YU04
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

746697:AEQSU RS13440
gene id: 746697:AEQSU_RS13440
uniprot id: I3YYV3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

746697:AEQSU RS13740
gene id: 746697:AEQSU_RS13740
uniprot id: I3YZ13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS04320
gene id: 746697:AEQSU_RS04320
uniprot id: I3YTR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS12440
gene id: 746697:AEQSU_RS12440
uniprot id: I3YYA4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS03590
gene id: 746697:AEQSU_RS03590
uniprot id: I3YTC5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

746697:AEQSU RS13490
gene id: 746697:AEQSU_RS13490
uniprot id: I3YYW4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS14360
gene id: 746697:AEQSU_RS14360
uniprot id: I3YZC9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

746697:AEQSU RS06035
gene id: 746697:AEQSU_RS06035
uniprot id: I3YUP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS11910
gene id: 746697:AEQSU_RS11910
uniprot id: I3YXZ3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS05675
gene id: 746697:AEQSU_RS05675
uniprot id: I3YUH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

746697:AEQSU RS05820
gene id: 746697:AEQSU_RS05820
uniprot id: I3YUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

746697:AEQSU RS00770
gene id: 746697:AEQSU_RS00770
uniprot id: I3YRR7
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS02405
gene id: 746697:AEQSU_RS02405
uniprot id: I3YSN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

746697:AEQSU RS10140
gene id: 746697:AEQSU_RS10140
uniprot id: I3YWZ7
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS05450
gene id: 746697:AEQSU_RS05450
uniprot id: I3YUD1
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

746697:AEQSU RS08440
gene id: 746697:AEQSU_RS08440
uniprot id: I3YW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

746697:AEQSU RS13095
gene id: 746697:AEQSU_RS13095
uniprot id: I3YYN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

746697:AEQSU RS02425
gene id: 746697:AEQSU_RS02425
uniprot id: I3YSP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

746697:AEQSU RS09080
gene id: 746697:AEQSU_RS09080
uniprot id: I3YWE3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

746697:AEQSU RS03275
gene id: 746697:AEQSU_RS03275
uniprot id: I3YT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

746697:AEQSU RS14935
gene id: 746697:AEQSU_RS14935
uniprot id: I3YZN9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS05915
gene id: 746697:AEQSU_RS05915
uniprot id: I3YUM3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

746697:AEQSU RS08435
gene id: 746697:AEQSU_RS08435
uniprot id: I3YW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

746697:AEQSU RS00980
gene id: 746697:AEQSU_RS00980
uniprot id: I3YRV9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS00435
gene id: 746697:AEQSU_RS00435
uniprot id: I3YRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

746697:AEQSU RS06165
gene id: 746697:AEQSU_RS06165
uniprot id: I3YUS1
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

746697:AEQSU RS13585
gene id: 746697:AEQSU_RS13585
uniprot id: I3YYY3
names: Similarity
messages: Belongs to the RutC family.

746697:AEQSU RS05735
gene id: 746697:AEQSU_RS05735
uniprot id: I3YUI7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS05140
gene id: 746697:AEQSU_RS05140
uniprot id: I3YU70
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

746697:AEQSU RS08350
gene id: 746697:AEQSU_RS08350
uniprot id: I3YW00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS06415
gene id: 746697:AEQSU_RS06415
uniprot id: I3YUX2
names: Similarity
messages: Belongs to the peptidase S15 family.

746697:AEQSU RS04450
gene id: 746697:AEQSU_RS04450
uniprot id: I3YTT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

746697:AEQSU RS09615
gene id: 746697:AEQSU_RS09615
uniprot id: I3YWP9
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS02185
gene id: 746697:AEQSU_RS02185
uniprot id: I3YSJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

746697:AEQSU RS02680
gene id: 746697:AEQSU_RS02680
uniprot id: I3YSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS05980
gene id: 746697:AEQSU_RS05980
uniprot id: I3YUN7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

746697:AEQSU RS10735
gene id: 746697:AEQSU_RS10735
uniprot id: I3YXB3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06540
gene id: 746697:AEQSU_RS06540
uniprot id: I3YUZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

746697:AEQSU RS09055
gene id: 746697:AEQSU_RS09055
uniprot id: I3YWD8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

746697:AEQSU RS04235
gene id: 746697:AEQSU_RS04235
uniprot id: I3YTP6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

746697:AEQSU RS08580
gene id: 746697:AEQSU_RS08580
uniprot id: I3YW45
names: Similarity
messages: Belongs to the alkaline phosphatase family.

746697:AEQSU RS10695
gene id: 746697:AEQSU_RS10695
uniprot id: I3YXA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

746697:AEQSU RS08820
gene id: 746697:AEQSU_RS08820
uniprot id: I3YW92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

746697:AEQSU RS05585
gene id: 746697:AEQSU_RS05585
uniprot id: I3YUF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

746697:AEQSU RS00145
gene id: 746697:AEQSU_RS00145
uniprot id: I3YRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

746697:AEQSU RS09520
gene id: 746697:AEQSU_RS09520
uniprot id: I3YWM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

746697:AEQSU RS01650
gene id: 746697:AEQSU_RS01650
uniprot id: I3YS86
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04395
gene id: 746697:AEQSU_RS04395
uniprot id: I3YTS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

746697:AEQSU RS06885
gene id: 746697:AEQSU_RS06885
uniprot id: I3YV66
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

746697:AEQSU RS09835
gene id: 746697:AEQSU_RS09835
uniprot id: I3YWU1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS15020
gene id: 746697:AEQSU_RS15020
uniprot id: I3YZQ6
names: Subcellular Location Annotation
messages: Secreted

746697:AEQSU RS14815
gene id: 746697:AEQSU_RS14815
uniprot id: I3YZL7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS04240
gene id: 746697:AEQSU_RS04240
uniprot id: I3YTP7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS15805
gene id: 746697:AEQSU_RS15805
uniprot id: I3Z064
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

746697:AEQSU RS15720
gene id: 746697:AEQSU_RS15720
uniprot id: I3Z050
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS05445
gene id: 746697:AEQSU_RS05445
uniprot id: I3YUD0
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

746697:AEQSU RS06940
gene id: 746697:AEQSU_RS06940
uniprot id: I3YV77
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

746697:AEQSU RS12095
gene id: 746697:AEQSU_RS12095
uniprot id: I3YY32
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS00310
gene id: 746697:AEQSU_RS00310
uniprot id: I3YRH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

746697:AEQSU RS15485
gene id: 746697:AEQSU_RS15485
uniprot id: I3Z001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS12845
gene id: 746697:AEQSU_RS12845
uniprot id: I3YYI3
names: Similarity
messages: Belongs to the asparagine synthetase family.

746697:AEQSU RS10665
gene id: 746697:AEQSU_RS10665
uniprot id: I3YX99
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06765
gene id: 746697:AEQSU_RS06765
uniprot id: I3YV42
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

746697:AEQSU RS09305
gene id: 746697:AEQSU_RS09305
uniprot id: I3YWI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15370
gene id: 746697:AEQSU_RS15370
uniprot id: I3YZX6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

746697:AEQSU RS12100
gene id: 746697:AEQSU_RS12100
uniprot id: I3YY33
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS09410
gene id: 746697:AEQSU_RS09410
uniprot id: I3YWK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS09945
gene id: 746697:AEQSU_RS09945
uniprot id: I3YWV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

746697:AEQSU RS02855
gene id: 746697:AEQSU_RS02855
uniprot id: I3YSX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

746697:AEQSU RS08420
gene id: 746697:AEQSU_RS08420
uniprot id: I3YW13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

746697:AEQSU RS11700
gene id: 746697:AEQSU_RS11700
uniprot id: I3YXV1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

746697:AEQSU RS01270
gene id: 746697:AEQSU_RS01270
uniprot id: I3YS17
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

746697:AEQSU RS00170
gene id: 746697:AEQSU_RS00170
uniprot id: I3YRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

746697:AEQSU RS00110
gene id: 746697:AEQSU_RS00110
uniprot id: I3YRD7
names: Similarity
messages: Belongs to the TPP enzyme family.

746697:AEQSU RS04150
gene id: 746697:AEQSU_RS04150
uniprot id: I3YTM9
names: Similarity
messages: Belongs to the Skp family.

746697:AEQSU RS05080
gene id: 746697:AEQSU_RS05080
uniprot id: I3YU58
names: Similarity
messages: Belongs to the ribF family.

746697:AEQSU RS16370
gene id: 746697:AEQSU_RS16370
uniprot id: I3YWN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

746697:AEQSU RS09515
gene id: 746697:AEQSU_RS09515
uniprot id: I3YWM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

746697:AEQSU RS02305
gene id: 746697:AEQSU_RS02305
uniprot id: I3YSL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

746697:AEQSU RS06730
gene id: 746697:AEQSU_RS06730
uniprot id: I3YV35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

746697:AEQSU RS05330
gene id: 746697:AEQSU_RS05330
uniprot id: I3YUA7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

746697:AEQSU RS11195
gene id: 746697:AEQSU_RS11195
uniprot id: I3YXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

746697:AEQSU RS09530
gene id: 746697:AEQSU_RS09530
uniprot id: I3YWN1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

746697:AEQSU RS07595
gene id: 746697:AEQSU_RS07595
uniprot id: I3YVK2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

746697:AEQSU RS05185
gene id: 746697:AEQSU_RS05185
uniprot id: I3YU79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS06805
gene id: 746697:AEQSU_RS06805
uniprot id: I3YV50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

746697:AEQSU RS13385
gene id: 746697:AEQSU_RS13385
uniprot id: I3YYU2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

746697:AEQSU RS08945
gene id: 746697:AEQSU_RS08945
uniprot id: I3YWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

746697:AEQSU RS03175
gene id: 746697:AEQSU_RS03175
uniprot id: I3YT40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

746697:AEQSU RS01140
gene id: 746697:AEQSU_RS01140
uniprot id: I3YRZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS06220
gene id: 746697:AEQSU_RS06220
uniprot id: I3YUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

746697:AEQSU RS12380
gene id: 746697:AEQSU_RS12380
uniprot id: I3YY92
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS11605
gene id: 746697:AEQSU_RS11605
uniprot id: I3YXT2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

746697:AEQSU RS02920
gene id: 746697:AEQSU_RS02920
uniprot id: I3YSY8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

746697:AEQSU RS11870
gene id: 746697:AEQSU_RS11870
uniprot id: I3YXY5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06315
gene id: 746697:AEQSU_RS06315
uniprot id: I3YUV0
names: Similarity
messages: Belongs to the peptidase M1 family.

746697:AEQSU RS06700
gene id: 746697:AEQSU_RS06700
uniprot id: I3YV28
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

746697:AEQSU RS13345
gene id: 746697:AEQSU_RS13345
uniprot id: I3YYT4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS11950
gene id: 746697:AEQSU_RS11950
uniprot id: I3YY02
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

746697:AEQSU RS01075
gene id: 746697:AEQSU_RS01075
uniprot id: I3YRX8
names: Similarity
messages: Belongs to the ParB family.

746697:AEQSU RS02415
gene id: 746697:AEQSU_RS02415
uniprot id: I3YSN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

746697:AEQSU RS12835
gene id: 746697:AEQSU_RS12835
uniprot id: I3YYI1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS00055
gene id: 746697:AEQSU_RS00055
uniprot id: I3YRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

746697:AEQSU RS02910
gene id: 746697:AEQSU_RS02910
uniprot id: I3YSY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

746697:AEQSU RS12220
gene id: 746697:AEQSU_RS12220
uniprot id: I3YY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

746697:AEQSU RS14290
gene id: 746697:AEQSU_RS14290
uniprot id: I3YZB5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

746697:AEQSU RS14580
gene id: 746697:AEQSU_RS14580
uniprot id: I3YZH1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS05390
gene id: 746697:AEQSU_RS05390
uniprot id: I3YUB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

746697:AEQSU RS02780
gene id: 746697:AEQSU_RS02780
uniprot id: I3YSW3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

746697:AEQSU RS02805
gene id: 746697:AEQSU_RS02805
uniprot id: I3YSW7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

746697:AEQSU RS03730
gene id: 746697:AEQSU_RS03730
uniprot id: I3YTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

746697:AEQSU RS05215
gene id: 746697:AEQSU_RS05215
uniprot id: I3YU85
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS03265
gene id: 746697:AEQSU_RS03265
uniprot id: I3YT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS10740
gene id: 746697:AEQSU_RS10740
uniprot id: I3YXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

746697:AEQSU RS10235
gene id: 746697:AEQSU_RS10235
uniprot id: I3YX16
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09425
gene id: 746697:AEQSU_RS09425
uniprot id: I3YWL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

746697:AEQSU RS09675
gene id: 746697:AEQSU_RS09675
uniprot id: I3YWR0
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

746697:AEQSU RS00440
gene id: 746697:AEQSU_RS00440
uniprot id: I3YRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

746697:AEQSU RS02640
gene id: 746697:AEQSU_RS02640
uniprot id: I3YST4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

746697:AEQSU RS02250
gene id: 746697:AEQSU_RS02250
uniprot id: I3YSK5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

746697:AEQSU RS11175
gene id: 746697:AEQSU_RS11175
uniprot id: I3YXK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

746697:AEQSU RS06350
gene id: 746697:AEQSU_RS06350
uniprot id: I3YUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS00465
gene id: 746697:AEQSU_RS00465
uniprot id: I3YRK6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06190
gene id: 746697:AEQSU_RS06190
uniprot id: I3YUS6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

746697:AEQSU RS00540
gene id: 746697:AEQSU_RS00540
uniprot id: I3YRM0
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

746697:AEQSU RS04035
gene id: 746697:AEQSU_RS04035
uniprot id: I3YTK7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

746697:AEQSU RS15985
gene id: 746697:AEQSU_RS15985
uniprot id: I3Z099
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

746697:AEQSU RS05100
gene id: 746697:AEQSU_RS05100
uniprot id: I3YU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

746697:AEQSU RS13850
gene id: 746697:AEQSU_RS13850
uniprot id: I3YZ36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS14490
gene id: 746697:AEQSU_RS14490
uniprot id: I3YZF4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

746697:AEQSU RS12735
gene id: 746697:AEQSU_RS12735
uniprot id: I3YYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

746697:AEQSU RS11165
gene id: 746697:AEQSU_RS11165
uniprot id: I3YXK1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

746697:AEQSU RS07135
gene id: 746697:AEQSU_RS07135
uniprot id: I3YVB7
names: Similarity
messages: Belongs to the asparaginase 1 family.

746697:AEQSU RS06520
gene id: 746697:AEQSU_RS06520
uniprot id: I3YUZ3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

746697:AEQSU RS00280
gene id: 746697:AEQSU_RS00280
uniprot id: I3YRH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

746697:AEQSU RS07860
gene id: 746697:AEQSU_RS07860
uniprot id: I3YVQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

746697:AEQSU RS06610
gene id: 746697:AEQSU_RS06610
uniprot id: I3YV10
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS15325
gene id: 746697:AEQSU_RS15325
uniprot id: I3YZW8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

746697:AEQSU RS04100
gene id: 746697:AEQSU_RS04100
uniprot id: I3YTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

746697:AEQSU RS12795
gene id: 746697:AEQSU_RS12795
uniprot id: I3YYH3
names: Similarity
messages: Belongs to the CvfB family.

746697:AEQSU RS07970
gene id: 746697:AEQSU_RS07970
uniprot id: I3YVS8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

746697:AEQSU RS10290
gene id: 746697:AEQSU_RS10290
uniprot id: I3YX25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

746697:AEQSU RS02000
gene id: 746697:AEQSU_RS02000
uniprot id: I3YSF5
names: Similarity
messages: Belongs to the CsgA/CsgB family.

746697:AEQSU RS00080
gene id: 746697:AEQSU_RS00080
uniprot id: I3YRD1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07490
gene id: 746697:AEQSU_RS07490
uniprot id: I3YVI4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

746697:AEQSU RS10515
gene id: 746697:AEQSU_RS10515
uniprot id: I3YX70
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

746697:AEQSU RS00225
gene id: 746697:AEQSU_RS00225
uniprot id: I3YRG0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15245
gene id: 746697:AEQSU_RS15245
uniprot id: I3YZV2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

746697:AEQSU RS14440
gene id: 746697:AEQSU_RS14440
uniprot id: I3YZE5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

746697:AEQSU RS15440
gene id: 746697:AEQSU_RS15440
uniprot id: I3YZZ1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

746697:AEQSU RS01265
gene id: 746697:AEQSU_RS01265
uniprot id: I3YS16
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

746697:AEQSU RS08925
gene id: 746697:AEQSU_RS08925
uniprot id: I3YWB3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS04735
gene id: 746697:AEQSU_RS04735
uniprot id: I3YTZ3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

746697:AEQSU RS09580
gene id: 746697:AEQSU_RS09580
uniprot id: I3YWP2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

746697:AEQSU RS14500
gene id: 746697:AEQSU_RS14500
uniprot id: I3YZF6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

746697:AEQSU RS06930
gene id: 746697:AEQSU_RS06930
uniprot id: I3YV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS13770
gene id: 746697:AEQSU_RS13770
uniprot id: I3YZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS11785
gene id: 746697:AEQSU_RS11785
uniprot id: I3YXW8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

746697:AEQSU RS14080
gene id: 746697:AEQSU_RS14080
uniprot id: I3YZ79
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

746697:AEQSU RS12920
gene id: 746697:AEQSU_RS12920
uniprot id: I3YYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

746697:AEQSU RS10300
gene id: 746697:AEQSU_RS10300
uniprot id: I3YX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

746697:AEQSU RS04030
gene id: 746697:AEQSU_RS04030
uniprot id: I3YTK6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

746697:AEQSU RS03410
gene id: 746697:AEQSU_RS03410
uniprot id: I3YT89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS01360
gene id: 746697:AEQSU_RS01360
uniprot id: I3YS29
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

746697:AEQSU RS09200
gene id: 746697:AEQSU_RS09200
uniprot id: I3YWG6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

746697:AEQSU RS13045
gene id: 746697:AEQSU_RS13045
uniprot id: I3YYM3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07920
gene id: 746697:AEQSU_RS07920
uniprot id: I3YVR9
names: Similarity
messages: Belongs to the thioredoxin family.

746697:AEQSU RS06995
gene id: 746697:AEQSU_RS06995
uniprot id: I3YV88
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

746697:AEQSU RS09185
gene id: 746697:AEQSU_RS09185
uniprot id: I3YWG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

746697:AEQSU RS09215
gene id: 746697:AEQSU_RS09215
uniprot id: I3YWG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS12160
gene id: 746697:AEQSU_RS12160
uniprot id: I3YY49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09285
gene id: 746697:AEQSU_RS09285
uniprot id: I3YWI3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15925
gene id: 746697:AEQSU_RS15925
uniprot id: I3Z088
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

746697:AEQSU RS15445
gene id: 746697:AEQSU_RS15445
uniprot id: I3YZZ2
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS02435
gene id: 746697:AEQSU_RS02435
uniprot id: I3YSP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

746697:AEQSU RS11335
gene id: 746697:AEQSU_RS11335
uniprot id: I3YXN4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

746697:AEQSU RS01110
gene id: 746697:AEQSU_RS01110
uniprot id: I3YRY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

746697:AEQSU RS04895
gene id: 746697:AEQSU_RS04895
uniprot id: I3YU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS02730
gene id: 746697:AEQSU_RS02730
uniprot id: I3YSV3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

746697:AEQSU RS14410
gene id: 746697:AEQSU_RS14410
uniprot id: I3YZD9
names: Similarity
messages: Belongs to the asparagine synthetase family.

746697:AEQSU RS02715
gene id: 746697:AEQSU_RS02715
uniprot id: I3YSV0
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06070
gene id: 746697:AEQSU_RS06070
uniprot id: I3YUQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

746697:AEQSU RS09860
gene id: 746697:AEQSU_RS09860
uniprot id: I3YWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS11895
gene id: 746697:AEQSU_RS11895
uniprot id: I3YXZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

746697:AEQSU RS12490
gene id: 746697:AEQSU_RS12490
uniprot id: I3YYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

746697:AEQSU RS00005
gene id: 746697:AEQSU_RS00005
uniprot id: I3YRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

746697:AEQSU RS06290
gene id: 746697:AEQSU_RS06290
uniprot id: I3YUU6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

746697:AEQSU RS14350
gene id: 746697:AEQSU_RS14350
uniprot id: I3YZC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS13125
gene id: 746697:AEQSU_RS13125
uniprot id: I3YYN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

746697:AEQSU RS03155
gene id: 746697:AEQSU_RS03155
uniprot id: I3YT36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS14890
gene id: 746697:AEQSU_RS14890
uniprot id: I3YZN0
names: Similarity
messages: Belongs to the CarB family.

746697:AEQSU RS13780
gene id: 746697:AEQSU_RS13780
uniprot id: I3YZ21
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

746697:AEQSU RS11560
gene id: 746697:AEQSU_RS11560
uniprot id: I3YXS3
names: Similarity
messages: Belongs to the peptidase M1 family.

746697:AEQSU RS02775
gene id: 746697:AEQSU_RS02775
uniprot id: I3YSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

746697:AEQSU RS02830
gene id: 746697:AEQSU_RS02830
uniprot id: I3YSX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

746697:AEQSU RS05575
gene id: 746697:AEQSU_RS05575
uniprot id: I3YUF7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

746697:AEQSU RS04850
gene id: 746697:AEQSU_RS04850
uniprot id: I3YU16
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS12870
gene id: 746697:AEQSU_RS12870
uniprot id: I3YYI8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

746697:AEQSU RS00765
gene id: 746697:AEQSU_RS00765
uniprot id: I3YRR6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

746697:AEQSU RS02260
gene id: 746697:AEQSU_RS02260
uniprot id: I3YSK7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

746697:AEQSU RS01440
gene id: 746697:AEQSU_RS01440
uniprot id: I3YS43
names: Similarity
messages: Belongs to the sterol desaturase family.

746697:AEQSU RS12330
gene id: 746697:AEQSU_RS12330
uniprot id: I3YY82
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

746697:AEQSU RS06970
gene id: 746697:AEQSU_RS06970
uniprot id: I3YV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

746697:AEQSU RS06480
gene id: 746697:AEQSU_RS06480
uniprot id: I3YUY5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS01235
gene id: 746697:AEQSU_RS01235
uniprot id: I3YS10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

746697:AEQSU RS01445
gene id: 746697:AEQSU_RS01445
uniprot id: I3YS44
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04840
gene id: 746697:AEQSU_RS04840
uniprot id: I3YU14
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

746697:AEQSU RS12365
gene id: 746697:AEQSU_RS12365
uniprot id: I3YY89
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

746697:AEQSU RS08995
gene id: 746697:AEQSU_RS08995
uniprot id: I3YWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS13700
gene id: 746697:AEQSU_RS13700
uniprot id: I3YZ05
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

746697:AEQSU RS14005
gene id: 746697:AEQSU_RS14005
uniprot id: I3YZ64
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS02045
gene id: 746697:AEQSU_RS02045
uniprot id: I3YSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

746697:AEQSU RS04400
gene id: 746697:AEQSU_RS04400
uniprot id: I3YTS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

746697:AEQSU RS10855
gene id: 746697:AEQSU_RS10855
uniprot id: I3YXD8
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09640
gene id: 746697:AEQSU_RS09640
uniprot id: I3YWQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

746697:AEQSU RS01720
gene id: 746697:AEQSU_RS01720
uniprot id: I3YS99
names: Similarity
messages: Belongs to the AAA ATPase family.

746697:AEQSU RS14795
gene id: 746697:AEQSU_RS14795
uniprot id: I3YZL3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS14710
gene id: 746697:AEQSU_RS14710
uniprot id: I3YZJ5
names: Similarity
messages: Belongs to the ArsC family.

746697:AEQSU RS14840
gene id: 746697:AEQSU_RS14840
uniprot id: I3YZM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS05240
gene id: 746697:AEQSU_RS05240
uniprot id: I3YU90
names: Similarity
messages: Belongs to the RecJ family.

746697:AEQSU RS06725
gene id: 746697:AEQSU_RS06725
uniprot id: I3YV34
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

746697:AEQSU RS10340
gene id: 746697:AEQSU_RS10340
uniprot id: I3YX35
names: Similarity
messages: Belongs to the CinA family.

746697:AEQSU RS05335
gene id: 746697:AEQSU_RS05335
uniprot id: I3YUA8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

746697:AEQSU RS14020
gene id: 746697:AEQSU_RS14020
uniprot id: I3YZ67
names: Similarity
messages: Belongs to the peptidase C40 family.

746697:AEQSU RS09390
gene id: 746697:AEQSU_RS09390
uniprot id: I3YWK4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS10040
gene id: 746697:AEQSU_RS10040
uniprot id: I3YWX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

746697:AEQSU RS06535
gene id: 746697:AEQSU_RS06535
uniprot id: I3YUZ5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06440
gene id: 746697:AEQSU_RS06440
uniprot id: I3YUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

746697:AEQSU RS08505
gene id: 746697:AEQSU_RS08505
uniprot id: I3YW30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

746697:AEQSU RS07375
gene id: 746697:AEQSU_RS07375
uniprot id: I3YVG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

746697:AEQSU RS06485
gene id: 746697:AEQSU_RS06485
uniprot id: I3YUY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS09585
gene id: 746697:AEQSU_RS09585
uniprot id: I3YWP3
names: Similarity
messages: Belongs to the citrate synthase family.

746697:AEQSU RS02945
gene id: 746697:AEQSU_RS02945
uniprot id: I3YSZ3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06420
gene id: 746697:AEQSU_RS06420
uniprot id: I3YUX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

746697:AEQSU RS06875
gene id: 746697:AEQSU_RS06875
uniprot id: I3YV64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

746697:AEQSU RS07725
gene id: 746697:AEQSU_RS07725
uniprot id: I3YVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

746697:AEQSU RS06320
gene id: 746697:AEQSU_RS06320
uniprot id: U3GKH2
names: Similarity
messages: Belongs to the SCO1/2 family.

746697:AEQSU RS09060
gene id: 746697:AEQSU_RS09060
uniprot id: I3YWD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

746697:AEQSU RS15860
gene id: 746697:AEQSU_RS15860
uniprot id: I3Z075
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

746697:AEQSU RS12565
gene id: 746697:AEQSU_RS12565
uniprot id: I3YYC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS14195
gene id: 746697:AEQSU_RS14195
uniprot id: I3YZ96
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07110
gene id: 746697:AEQSU_RS07110
uniprot id: I3YVB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

746697:AEQSU RS03180
gene id: 746697:AEQSU_RS03180
uniprot id: I3YT43
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

746697:AEQSU RS05580
gene id: 746697:AEQSU_RS05580
uniprot id: I3YUF8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

746697:AEQSU RS05780
gene id: 746697:AEQSU_RS05780
uniprot id: I3YUJ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

746697:AEQSU RS12910
gene id: 746697:AEQSU_RS12910
uniprot id: I3YYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

746697:AEQSU RS06225
gene id: 746697:AEQSU_RS06225
uniprot id: I3YUT3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

746697:AEQSU RS04075
gene id: 746697:AEQSU_RS04075
uniprot id: I3YTL5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS14730
gene id: 746697:AEQSU_RS14730
uniprot id: I3YZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

746697:AEQSU RS14545
gene id: 746697:AEQSU_RS14545
uniprot id: I3YZG4
names: Similarity
messages: Belongs to the Dps family.

746697:AEQSU RS03075
gene id: 746697:AEQSU_RS03075
uniprot id: I3YT19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS10890
gene id: 746697:AEQSU_RS10890
uniprot id: I3YXE5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

746697:AEQSU RS05475
gene id: 746697:AEQSU_RS05475
uniprot id: I3YUD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

746697:AEQSU RS04910
gene id: 746697:AEQSU_RS04910
uniprot id: I3YU28
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

746697:AEQSU RS07335
gene id: 746697:AEQSU_RS07335
uniprot id: I3YVF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

746697:AEQSU RS11990
gene id: 746697:AEQSU_RS11990
uniprot id: I3YY10
names: Similarity
messages: Belongs to the DNA photolyase family.

746697:AEQSU RS06695
gene id: 746697:AEQSU_RS06695
uniprot id: I3YV27
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

746697:AEQSU RS11865
gene id: 746697:AEQSU_RS11865
uniprot id: I3YXY4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

746697:AEQSU RS06110
gene id: 746697:AEQSU_RS06110
uniprot id: I3YUR1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

746697:AEQSU RS09565
gene id: 746697:AEQSU_RS09565
uniprot id: I3YWN9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

746697:AEQSU RS13310
gene id: 746697:AEQSU_RS13310
uniprot id: I3YYS6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

746697:AEQSU RS10950
gene id: 746697:AEQSU_RS10950
uniprot id: I3YXF7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

746697:AEQSU RS04385
gene id: 746697:AEQSU_RS04385
uniprot id: I3YTS6
names: Similarity
messages: Belongs to the cytochrome P450 family.

746697:AEQSU RS06570
gene id: 746697:AEQSU_RS06570
uniprot id: I3YV02
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

746697:AEQSU RS15480
gene id: 746697:AEQSU_RS15480
uniprot id: I3Z000
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

746697:AEQSU RS13100
gene id: 746697:AEQSU_RS13100
uniprot id: I3YYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

746697:AEQSU RS11525
gene id: 746697:AEQSU_RS11525
uniprot id: I3YXR6
names: Similarity
messages: Belongs to the peptidase M4 family.

746697:AEQSU RS01875
gene id: 746697:AEQSU_RS01875
uniprot id: I3YSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

746697:AEQSU RS11345
gene id: 746697:AEQSU_RS11345
uniprot id: I3YXN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

746697:AEQSU RS08055
gene id: 746697:AEQSU_RS08055
uniprot id: I3YVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

746697:AEQSU RS02055
gene id: 746697:AEQSU_RS02055
uniprot id: I3YSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

746697:AEQSU RS09770
gene id: 746697:AEQSU_RS09770
uniprot id: I3YWS9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS05960
gene id: 746697:AEQSU_RS05960
uniprot id: I3YUN3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04460
gene id: 746697:AEQSU_RS04460
uniprot id: I3YTU1
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS09435
gene id: 746697:AEQSU_RS09435
uniprot id: I3YWL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

746697:AEQSU RS15975
gene id: 746697:AEQSU_RS15975
uniprot id: I3Z097
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

746697:AEQSU RS11860
gene id: 746697:AEQSU_RS11860
uniprot id: I3YXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

746697:AEQSU RS05405
gene id: 746697:AEQSU_RS05405
uniprot id: I3YUC2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS05085
gene id: 746697:AEQSU_RS05085
uniprot id: I3YU59
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09385
gene id: 746697:AEQSU_RS09385
uniprot id: I3YWK3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

746697:AEQSU RS05425
gene id: 746697:AEQSU_RS05425
uniprot id: I3YUC6
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

746697:AEQSU RS02125
gene id: 746697:AEQSU_RS02125
uniprot id: I3YSI0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

746697:AEQSU RS13910
gene id: 746697:AEQSU_RS13910
uniprot id: I3YZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

746697:AEQSU RS02850
gene id: 746697:AEQSU_RS02850
uniprot id: I3YSX6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

746697:AEQSU RS06330
gene id: 746697:AEQSU_RS06330
uniprot id: I3YUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

746697:AEQSU RS05205
gene id: 746697:AEQSU_RS05205
uniprot id: I3YU83
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS11180
gene id: 746697:AEQSU_RS11180
uniprot id: I3YXK4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

746697:AEQSU RS09500
gene id: 746697:AEQSU_RS09500
uniprot id: I3YWM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

746697:AEQSU RS06685
gene id: 746697:AEQSU_RS06685
uniprot id: I3YV25
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

746697:AEQSU RS09545
gene id: 746697:AEQSU_RS09545
uniprot id: I3YWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

746697:AEQSU RS01770
gene id: 746697:AEQSU_RS01770
uniprot id: I3YSA9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

746697:AEQSU RS15185
gene id: 746697:AEQSU_RS15185
uniprot id: I3YZT9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

746697:AEQSU RS07925
gene id: 746697:AEQSU_RS07925
uniprot id: I3YVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

746697:AEQSU RS08835
gene id: 746697:AEQSU_RS08835
uniprot id: I3YW95
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06890
gene id: 746697:AEQSU_RS06890
uniprot id: I3YV67
names: Similarity
messages: Belongs to the UPF0045 family.

746697:AEQSU RS15130
gene id: 746697:AEQSU_RS15130
uniprot id: I3YZS8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

746697:AEQSU RS14470
gene id: 746697:AEQSU_RS14470
uniprot id: I3YZF1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

746697:AEQSU RS12585
gene id: 746697:AEQSU_RS12585
uniprot id: I3YYD3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

746697:AEQSU RS10375
gene id: 746697:AEQSU_RS10375
uniprot id: I3YX43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

746697:AEQSU RS00580
gene id: 746697:AEQSU_RS00580
uniprot id: I3YRM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

746697:AEQSU RS00190
gene id: 746697:AEQSU_RS00190
uniprot id: I3YRF3
names: Similarity
messages: Belongs to the BshC family.

746697:AEQSU RS00140
gene id: 746697:AEQSU_RS00140
uniprot id: I3YRE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS03105
gene id: 746697:AEQSU_RS03105
uniprot id: I3YT25
names: Similarity
messages: Belongs to the DinB family.

746697:AEQSU RS07350
gene id: 746697:AEQSU_RS07350
uniprot id: I3YVF7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

746697:AEQSU RS14265
gene id: 746697:AEQSU_RS14265
uniprot id: I3YZB0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

746697:AEQSU RS05745
gene id: 746697:AEQSU_RS05745
uniprot id: I3YUI9
names: Similarity
messages: Belongs to the aspartokinase family.

746697:AEQSU RS14495
gene id: 746697:AEQSU_RS14495
uniprot id: I3YZF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

746697:AEQSU RS04445
gene id: 746697:AEQSU_RS04445
uniprot id: I3YTT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

746697:AEQSU RS07455
gene id: 746697:AEQSU_RS07455
uniprot id: I3YVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

746697:AEQSU RS10590
gene id: 746697:AEQSU_RS10590
uniprot id: I3YX85
names: Similarity
messages: Belongs to the CIA30 family.

746697:AEQSU RS04380
gene id: 746697:AEQSU_RS04380
uniprot id: I3YTS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

746697:AEQSU RS13190
gene id: 746697:AEQSU_RS13190
uniprot id: I3YYQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

746697:AEQSU RS10620
gene id: 746697:AEQSU_RS10620
uniprot id: I3YX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

746697:AEQSU RS02925
gene id: 746697:AEQSU_RS02925
uniprot id: I3YSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

746697:AEQSU RS11150
gene id: 746697:AEQSU_RS11150
uniprot id: I3YXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

746697:AEQSU RS07275
gene id: 746697:AEQSU_RS07275
uniprot id: I3YVE3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

746697:AEQSU RS13495
gene id: 746697:AEQSU_RS13495
uniprot id: I3YYW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

746697:AEQSU RS07680
gene id: 746697:AEQSU_RS07680
uniprot id: I3YVM1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

746697:AEQSU RS13180
gene id: 746697:AEQSU_RS13180
uniprot id: I3YYQ0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

746697:AEQSU RS12885
gene id: 746697:AEQSU_RS12885
uniprot id: I3YYJ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

746697:AEQSU RS08445
gene id: 746697:AEQSU_RS08445
uniprot id: I3YW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

746697:AEQSU RS12580
gene id: 746697:AEQSU_RS12580
uniprot id: I3YYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

746697:AEQSU RS02840
gene id: 746697:AEQSU_RS02840
uniprot id: I3YSX4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

746697:AEQSU RS14610
gene id: 746697:AEQSU_RS14610
uniprot id: I3YZH7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

746697:AEQSU RS13590
gene id: 746697:AEQSU_RS13590
uniprot id: I3YYY4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

746697:AEQSU RS05685
gene id: 746697:AEQSU_RS05685
uniprot id: I3YUH7
names: Similarity
messages: Belongs to the UPF0102 family.

746697:AEQSU RS05870
gene id: 746697:AEQSU_RS05870
uniprot id: I3YUL4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

746697:AEQSU RS07395
gene id: 746697:AEQSU_RS07395
uniprot id: I3YVG6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

746697:AEQSU RS01410
gene id: 746697:AEQSU_RS01410
uniprot id: I3YS39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

746697:AEQSU RS12730
gene id: 746697:AEQSU_RS12730
uniprot id: I3YYG0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

746697:AEQSU RS05270
gene id: 746697:AEQSU_RS05270
uniprot id: I3YU96
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS07260
gene id: 746697:AEQSU_RS07260
uniprot id: I3YVE0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

746697:AEQSU RS09450
gene id: 746697:AEQSU_RS09450
uniprot id: I3YWL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

746697:AEQSU RS11825
gene id: 746697:AEQSU_RS11825
uniprot id: I3YXX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

746697:AEQSU RS11745
gene id: 746697:AEQSU_RS11745
uniprot id: I3YXW0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

746697:AEQSU RS15665
gene id: 746697:AEQSU_RS15665
uniprot id: I3Z039
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS10770
gene id: 746697:AEQSU_RS10770
uniprot id: I3YXC0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

746697:AEQSU RS06430
gene id: 746697:AEQSU_RS06430
uniprot id: I3YUX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

746697:AEQSU RS08430
gene id: 746697:AEQSU_RS08430
uniprot id: I3YW15
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

746697:AEQSU RS10940
gene id: 746697:AEQSU_RS10940
uniprot id: I3YXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

746697:AEQSU RS13195
gene id: 746697:AEQSU_RS13195
uniprot id: I3YYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

746697:AEQSU RS05380
gene id: 746697:AEQSU_RS05380
uniprot id: I3YUB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

746697:AEQSU RS10355
gene id: 746697:AEQSU_RS10355
uniprot id: I3YX39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

746697:AEQSU RS06710
gene id: 746697:AEQSU_RS06710
uniprot id: I3YV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

746697:AEQSU RS13745
gene id: 746697:AEQSU_RS13745
uniprot id: I3YZ14
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

746697:AEQSU RS09940
gene id: 746697:AEQSU_RS09940
uniprot id: I3YWV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

746697:AEQSU RS08530
gene id: 746697:AEQSU_RS08530
uniprot id: I3YW35
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

746697:AEQSU RS11660
gene id: 746697:AEQSU_RS11660
uniprot id: I3YXU3
names: Similarity
messages: Belongs to the UPF0173 family.

746697:AEQSU RS07160
gene id: 746697:AEQSU_RS07160
uniprot id: I3YVC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

746697:AEQSU RS02235
gene id: 746697:AEQSU_RS02235
uniprot id: I3YSK2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

746697:AEQSU RS04795
gene id: 746697:AEQSU_RS04795
uniprot id: I3YU05
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

746697:AEQSU RS09650
gene id: 746697:AEQSU_RS09650
uniprot id: I3YWQ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

746697:AEQSU RS02540
gene id: 746697:AEQSU_RS02540
uniprot id: I3YSR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

746697:AEQSU RS07085
gene id: 746697:AEQSU_RS07085
uniprot id: I3YVA6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

746697:AEQSU RS04310
gene id: 746697:AEQSU_RS04310
uniprot id: I3YTR1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS01380
gene id: 746697:AEQSU_RS01380
uniprot id: I3YS33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS06400
gene id: 746697:AEQSU_RS06400
uniprot id: I3YUW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15115
gene id: 746697:AEQSU_RS15115
uniprot id: I3YZS5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

746697:AEQSU RS13935
gene id: 746697:AEQSU_RS13935
uniprot id: I3YZ53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

746697:AEQSU RS13360
gene id: 746697:AEQSU_RS13360
uniprot id: I3YYT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

746697:AEQSU RS10275
gene id: 746697:AEQSU_RS10275
uniprot id: I3YX22
names: Similarity
messages: Belongs to the heat shock protein 90 family.

746697:AEQSU RS14525
gene id: 746697:AEQSU_RS14525
uniprot id: I3YZG1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

746697:AEQSU RS03580
gene id: 746697:AEQSU_RS03580
uniprot id: I3YTC3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

746697:AEQSU RS15260
gene id: 746697:AEQSU_RS15260
uniprot id: I3YZV5
names: Similarity
messages: Belongs to the SusD family.

746697:AEQSU RS14015
gene id: 746697:AEQSU_RS14015
uniprot id: I3YZ66
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

746697:AEQSU RS08485
gene id: 746697:AEQSU_RS08485
uniprot id: I3YW26
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

746697:AEQSU RS05950
gene id: 746697:AEQSU_RS05950
uniprot id: I3YUN1
names: Similarity
messages: Belongs to the asparagine synthetase family.

746697:AEQSU RS03170
gene id: 746697:AEQSU_RS03170
uniprot id: I3YT39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

746697:AEQSU RS12075
gene id: 746697:AEQSU_RS12075
uniprot id: I3YY28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

746697:AEQSU RS12050
gene id: 746697:AEQSU_RS12050
uniprot id: I3YY23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS02445
gene id: 746697:AEQSU_RS02445
uniprot id: I3YSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

746697:AEQSU RS05620
gene id: 746697:AEQSU_RS05620
uniprot id: I3YUG5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

746697:AEQSU RS09310
gene id: 746697:AEQSU_RS09310
uniprot id: I3YWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

746697:AEQSU RS13110
gene id: 746697:AEQSU_RS13110
uniprot id: I3YYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

746697:AEQSU RS09870
gene id: 746697:AEQSU_RS09870
uniprot id: I3YWU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

746697:AEQSU RS14535
gene id: 746697:AEQSU_RS14535
uniprot id: I3YZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

746697:AEQSU RS08525
gene id: 746697:AEQSU_RS08525
uniprot id: I3YW34
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

746697:AEQSU RS03375
gene id: 746697:AEQSU_RS03375
uniprot id: I3YT82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

746697:AEQSU RS07250
gene id: 746697:AEQSU_RS07250
uniprot id: I3YVD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

746697:AEQSU RS09970
gene id: 746697:AEQSU_RS09970
uniprot id: I3YWW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS01285
gene id: 746697:AEQSU_RS01285
uniprot id: I3YS20
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

746697:AEQSU RS05815
gene id: 746697:AEQSU_RS05815
uniprot id: I3YUK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

746697:AEQSU RS00060
gene id: 746697:AEQSU_RS00060
uniprot id: I3YRC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

746697:AEQSU RS06665
gene id: 746697:AEQSU_RS06665
uniprot id: I3YV21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

746697:AEQSU RS08475
gene id: 746697:AEQSU_RS08475
uniprot id: I3YW24
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS02660
gene id: 746697:AEQSU_RS02660
uniprot id: I3YST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS09255
gene id: 746697:AEQSU_RS09255
uniprot id: I3YWH7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

746697:AEQSU RS01365
gene id: 746697:AEQSU_RS01365
uniprot id: I3YS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

746697:AEQSU RS12785
gene id: 746697:AEQSU_RS12785
uniprot id: I3YYH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

746697:AEQSU RS06310
gene id: 746697:AEQSU_RS06310
uniprot id: I3YUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

746697:AEQSU RS02130
gene id: 746697:AEQSU_RS02130
uniprot id: I3YSI1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS09440
gene id: 746697:AEQSU_RS09440
uniprot id: I3YWL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

746697:AEQSU RS04085
gene id: 746697:AEQSU_RS04085
uniprot id: I3YTL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

746697:AEQSU RS09555
gene id: 746697:AEQSU_RS09555
uniprot id: I3YWN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

746697:AEQSU RS09950
gene id: 746697:AEQSU_RS09950
uniprot id: I3YWV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

746697:AEQSU RS14175
gene id: 746697:AEQSU_RS14175
uniprot id: I3YZ92
names: Similarity
messages: Belongs to the SAICAR synthetase family.

746697:AEQSU RS09445
gene id: 746697:AEQSU_RS09445
uniprot id: I3YWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

746697:AEQSU RS00025
gene id: 746697:AEQSU_RS00025
uniprot id: I3YRB9
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS11015
gene id: 746697:AEQSU_RS11015
uniprot id: I3YXH1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

746697:AEQSU RS09495
gene id: 746697:AEQSU_RS09495
uniprot id: I3YWM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

746697:AEQSU RS11650
gene id: 746697:AEQSU_RS11650
uniprot id: I3YXU1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09605
gene id: 746697:AEQSU_RS09605
uniprot id: I3YWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

746697:AEQSU RS07510
gene id: 746697:AEQSU_RS07510
uniprot id: I3YVI8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

746697:AEQSU RS13225
gene id: 746697:AEQSU_RS13225
uniprot id: I3YYQ9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

746697:AEQSU RS06195
gene id: 746697:AEQSU_RS06195
uniprot id: I3YUS7
names: Similarity
messages: Belongs to the peptidase S8 family.

746697:AEQSU RS13215
gene id: 746697:AEQSU_RS13215
uniprot id: I3YYQ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

746697:AEQSU RS03425
gene id: 746697:AEQSU_RS03425
uniprot id: I3YT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

746697:AEQSU RS04800
gene id: 746697:AEQSU_RS04800
uniprot id: I3YU06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

746697:AEQSU RS15840
gene id: 746697:AEQSU_RS15840
uniprot id: I3Z071
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

746697:AEQSU RS07180
gene id: 746697:AEQSU_RS07180
uniprot id: I3YVC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS15980
gene id: 746697:AEQSU_RS15980
uniprot id: I3Z098
names: Similarity
messages: Belongs to the LOG family.

746697:AEQSU RS08005
gene id: 746697:AEQSU_RS08005
uniprot id: I3YVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

746697:AEQSU RS03505
gene id: 746697:AEQSU_RS03505
uniprot id: I3YTA8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

746697:AEQSU RS13400
gene id: 746697:AEQSU_RS13400
uniprot id: I3YYU5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

746697:AEQSU RS06795
gene id: 746697:AEQSU_RS06795
uniprot id: I3YV48
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

746697:AEQSU RS05075
gene id: 746697:AEQSU_RS05075
uniprot id: I3YU57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

746697:AEQSU RS09470
gene id: 746697:AEQSU_RS09470
uniprot id: I3YWL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

746697:AEQSU RS04740
gene id: 746697:AEQSU_RS04740
uniprot id: I3YTZ4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

746697:AEQSU RS12805
gene id: 746697:AEQSU_RS12805
uniprot id: I3YYH5
names: Similarity
messages: Belongs to the peptidase C1 family.

746697:AEQSU RS04710
gene id: 746697:AEQSU_RS04710
uniprot id: I3YTZ0
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS14260
gene id: 746697:AEQSU_RS14260
uniprot id: I3YZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

746697:AEQSU RS09925
gene id: 746697:AEQSU_RS09925
uniprot id: I3YWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

746697:AEQSU RS01965
gene id: 746697:AEQSU_RS01965
uniprot id: I3YSE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

746697:AEQSU RS04210
gene id: 746697:AEQSU_RS04210
uniprot id: I3YTP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

746697:AEQSU RS03885
gene id: 746697:AEQSU_RS03885
uniprot id: I3YTH9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

746697:AEQSU RS14050
gene id: 746697:AEQSU_RS14050
uniprot id: I3YZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

746697:AEQSU RS00240
gene id: 746697:AEQSU_RS00240
uniprot id: I3YRG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS03515
gene id: 746697:AEQSU_RS03515
uniprot id: I3YTB0
names: Similarity
messages: Belongs to the fabD family.

746697:AEQSU RS03720
gene id: 746697:AEQSU_RS03720
uniprot id: I3YTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS07185
gene id: 746697:AEQSU_RS07185
uniprot id: I3YVC6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS06590
gene id: 746697:AEQSU_RS06590
uniprot id: I3YV06
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

746697:AEQSU RS02390
gene id: 746697:AEQSU_RS02390
uniprot id: I3YSN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

746697:AEQSU RS07320
gene id: 746697:AEQSU_RS07320
uniprot id: I3YVF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

746697:AEQSU RS04370
gene id: 746697:AEQSU_RS04370
uniprot id: I3YTS3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

746697:AEQSU RS00525
gene id: 746697:AEQSU_RS00525
uniprot id: I3YRL7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

746697:AEQSU RS13300
gene id: 746697:AEQSU_RS13300
uniprot id: I3YYS4
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09550
gene id: 746697:AEQSU_RS09550
uniprot id: I3YWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

746697:AEQSU RS08630
gene id: 746697:AEQSU_RS08630
uniprot id: I3YW55
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

746697:AEQSU RS13200
gene id: 746697:AEQSU_RS13200
uniprot id: I3YYQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

746697:AEQSU RS07995
gene id: 746697:AEQSU_RS07995
uniprot id: I3YVT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

746697:AEQSU RS14455
gene id: 746697:AEQSU_RS14455
uniprot id: I3YZE8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

746697:AEQSU RS05145
gene id: 746697:AEQSU_RS05145
uniprot id: I3YU71
names: Similarity
messages: Belongs to the peptidase S9A family.

746697:AEQSU RS13545
gene id: 746697:AEQSU_RS13545
uniprot id: I3YYX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

746697:AEQSU RS02230
gene id: 746697:AEQSU_RS02230
uniprot id: I3YSK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

746697:AEQSU RS09485
gene id: 746697:AEQSU_RS09485
uniprot id: I3YWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

746697:AEQSU RS13505
gene id: 746697:AEQSU_RS13505
uniprot id: I3YYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

746697:AEQSU RS02075
gene id: 746697:AEQSU_RS02075
uniprot id: I3YSH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

746697:AEQSU RS15160
gene id: 746697:AEQSU_RS15160
uniprot id: I3YZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

746697:AEQSU RS07055
gene id: 746697:AEQSU_RS07055
uniprot id: I3YVA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS12450
gene id: 746697:AEQSU_RS12450
uniprot id: I3YYA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

746697:AEQSU RS06660
gene id: 746697:AEQSU_RS06660
uniprot id: I3YV20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

746697:AEQSU RS14245
gene id: 746697:AEQSU_RS14245
uniprot id: I3YZA6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

746697:AEQSU RS07405
gene id: 746697:AEQSU_RS07405
uniprot id: I3YVG8
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS10085
gene id: 746697:AEQSU_RS10085
uniprot id: I3YWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

746697:AEQSU RS06895
gene id: 746697:AEQSU_RS06895
uniprot id: I3YV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

746697:AEQSU RS11840
gene id: 746697:AEQSU_RS11840
uniprot id: I3YXX9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

746697:AEQSU RS14325
gene id: 746697:AEQSU_RS14325
uniprot id: I3YZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS02295
gene id: 746697:AEQSU_RS02295
uniprot id: I3YSL5
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

746697:AEQSU RS01275
gene id: 746697:AEQSU_RS01275
uniprot id: I3YS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS07155
gene id: 746697:AEQSU_RS07155
uniprot id: I3YVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

746697:AEQSU RS08190
gene id: 746697:AEQSU_RS08190
uniprot id: I3YVX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

746697:AEQSU RS05385
gene id: 746697:AEQSU_RS05385
uniprot id: I3YUB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

746697:AEQSU RS08275
gene id: 746697:AEQSU_RS08275
uniprot id: I3YVY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS02575
gene id: 746697:AEQSU_RS02575
uniprot id: I3YSS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

746697:AEQSU RS02585
gene id: 746697:AEQSU_RS02585
uniprot id: I3YSS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

746697:AEQSU RS01430
gene id: 746697:AEQSU_RS01430
uniprot id: I3YS41
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

746697:AEQSU RS03525
gene id: 746697:AEQSU_RS03525
uniprot id: I3YTB2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

746697:AEQSU RS00550
gene id: 746697:AEQSU_RS00550
uniprot id: U3GJZ8
names: Similarity
messages: Belongs to the SCO1/2 family.

746697:AEQSU RS06135
gene id: 746697:AEQSU_RS06135
uniprot id: I3YUR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

746697:AEQSU RS09850
gene id: 746697:AEQSU_RS09850
uniprot id: I3YWU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS06510
gene id: 746697:AEQSU_RS06510
uniprot id: I3YUZ1
names: Subunit
messages: Homodimer.

746697:AEQSU RS11295
gene id: 746697:AEQSU_RS11295
uniprot id: I3YXM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

746697:AEQSU RS03160
gene id: 746697:AEQSU_RS03160
uniprot id: I3YT37
names: Similarity
messages: Belongs to the TrpC family.

746697:AEQSU RS11945
gene id: 746697:AEQSU_RS11945
uniprot id: I3YY01
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

746697:AEQSU RS01515
gene id: 746697:AEQSU_RS01515
uniprot id: I3YS58
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

746697:AEQSU RS14950
gene id: 746697:AEQSU_RS14950
uniprot id: I3YZP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

746697:AEQSU RS12780
gene id: 746697:AEQSU_RS12780
uniprot id: I3YYH0
names: Similarity
messages: Belongs to the isochorismate synthase family.

746697:AEQSU RS00070
gene id: 746697:AEQSU_RS00070
uniprot id: I3YRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

746697:AEQSU RS07965
gene id: 746697:AEQSU_RS07965
uniprot id: I3YVS7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

746697:AEQSU RS07010
gene id: 746697:AEQSU_RS07010
uniprot id: I3YV91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

746697:AEQSU RS15605
gene id: 746697:AEQSU_RS15605
uniprot id: I3Z028
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS02815
gene id: 746697:AEQSU_RS02815
uniprot id: I3YSW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

746697:AEQSU RS00035
gene id: 746697:AEQSU_RS00035
uniprot id: I3YRC1
names: Similarity
messages: Belongs to the pirin family.

746697:AEQSU RS06635
gene id: 746697:AEQSU_RS06635
uniprot id: I3YV15
names: Similarity
messages: Belongs to the DprA/Smf family.

746697:AEQSU RS07020
gene id: 746697:AEQSU_RS07020
uniprot id: I3YV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

746697:AEQSU RS10565
gene id: 746697:AEQSU_RS10565
uniprot id: I3YX80
names: Similarity
messages: Belongs to the glutathione peroxidase family.

746697:AEQSU RS02025
gene id: 746697:AEQSU_RS02025
uniprot id: I3YSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS09420
gene id: 746697:AEQSU_RS09420
uniprot id: I3YWK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

746697:AEQSU RS13165
gene id: 746697:AEQSU_RS13165
uniprot id: I3YYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

746697:AEQSU RS07670
gene id: 746697:AEQSU_RS07670
uniprot id: I3YVL8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

746697:AEQSU RS15265
gene id: 746697:AEQSU_RS15265
uniprot id: I3YZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

746697:AEQSU RS13210
gene id: 746697:AEQSU_RS13210
uniprot id: I3YYQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

746697:AEQSU RS04865
gene id: 746697:AEQSU_RS04865
uniprot id: I3YU19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

746697:AEQSU RS02765
gene id: 746697:AEQSU_RS02765
uniprot id: I3YSW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

746697:AEQSU RS10310
gene id: 746697:AEQSU_RS10310
uniprot id: I3YX29
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

746697:AEQSU RS09460
gene id: 746697:AEQSU_RS09460
uniprot id: I3YWL7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

746697:AEQSU RS15460
gene id: 746697:AEQSU_RS15460
uniprot id: I3YZZ5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

746697:AEQSU RS05810
gene id: 746697:AEQSU_RS05810
uniprot id: I3YUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

746697:AEQSU RS09575
gene id: 746697:AEQSU_RS09575
uniprot id: I3YWP1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

746697:AEQSU RS08535
gene id: 746697:AEQSU_RS08535
uniprot id: I3YW36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

746697:AEQSU RS03595
gene id: 746697:AEQSU_RS03595
uniprot id: I3YTC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

746697:AEQSU RS09430
gene id: 746697:AEQSU_RS09430
uniprot id: I3YWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

746697:AEQSU RS09320
gene id: 746697:AEQSU_RS09320
uniprot id: I3YWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

746697:AEQSU RS10745
gene id: 746697:AEQSU_RS10745
uniprot id: I3YXB5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

746697:AEQSU RS12955
gene id: 746697:AEQSU_RS12955
uniprot id: I3YYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

746697:AEQSU RS15940
gene id: 746697:AEQSU_RS15940
uniprot id: I3Z091
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS12135
gene id: 746697:AEQSU_RS12135
uniprot id: I3YY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

746697:AEQSU RS01325
gene id: 746697:AEQSU_RS01325
uniprot id: I3YS23
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS01125
gene id: 746697:AEQSU_RS01125
uniprot id: I3YRY8
names: Similarity
messages: Belongs to the DEAD box helicase family.

746697:AEQSU RS14515
gene id: 746697:AEQSU_RS14515
uniprot id: I3YZF9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

746697:AEQSU RS10320
gene id: 746697:AEQSU_RS10320
uniprot id: I3YX31
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

746697:AEQSU RS10345
gene id: 746697:AEQSU_RS10345
uniprot id: I3YX36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

746697:AEQSU RS14645
gene id: 746697:AEQSU_RS14645
uniprot id: I3YZI4
names: Similarity
messages: Belongs to the threonine aldolase family.

746697:AEQSU RS03445
gene id: 746697:AEQSU_RS03445
uniprot id: I3YT96
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

746697:AEQSU RS00195
gene id: 746697:AEQSU_RS00195
uniprot id: I3YRF4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

746697:AEQSU RS02245
gene id: 746697:AEQSU_RS02245
uniprot id: I3YSK4
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

746697:AEQSU RS02370
gene id: 746697:AEQSU_RS02370
uniprot id: I3YSN0
names: Similarity
messages: Belongs to the peptidase S51 family.

746697:AEQSU RS03550
gene id: 746697:AEQSU_RS03550
uniprot id: I3YTB7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

746697:AEQSU RS14000
gene id: 746697:AEQSU_RS14000
uniprot id: I3YZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

746697:AEQSU RS08605
gene id: 746697:AEQSU_RS08605
uniprot id: I3YW50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

746697:AEQSU RS02545
gene id: 746697:AEQSU_RS02545
uniprot id: I3YSR6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS03695
gene id: 746697:AEQSU_RS03695
uniprot id: I3YTE3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

746697:AEQSU RS00880
gene id: 746697:AEQSU_RS00880
uniprot id: I3YRT6
names: Similarity
messages: Belongs to the HsdR family.

746697:AEQSU RS01460
gene id: 746697:AEQSU_RS01460
uniprot id: I3YS47
names: Subcellular Location Annotation
messages: Mitochondrion

746697:AEQSU RS06280
gene id: 746697:AEQSU_RS06280
uniprot id: I3YUU4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

746697:AEQSU RS12400
gene id: 746697:AEQSU_RS12400
uniprot id: I3YY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

746697:AEQSU RS12850
gene id: 746697:AEQSU_RS12850
uniprot id: I3YYI4
names: Similarity
messages: Belongs to the DEAD box helicase family.

746697:AEQSU RS01525
gene id: 746697:AEQSU_RS01525
uniprot id: I3YS60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

746697:AEQSU RS13280
gene id: 746697:AEQSU_RS13280
uniprot id: I3YYS0
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04315
gene id: 746697:AEQSU_RS04315
uniprot id: I3YTR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

746697:AEQSU RS05200
gene id: 746697:AEQSU_RS05200
uniprot id: I3YU82
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

746697:AEQSU RS11010
gene id: 746697:AEQSU_RS11010
uniprot id: I3YXH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

746697:AEQSU RS11355
gene id: 746697:AEQSU_RS11355
uniprot id: I3YXN8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

746697:AEQSU RS05360
gene id: 746697:AEQSU_RS05360
uniprot id: I3YUB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

746697:AEQSU RS11505
gene id: 746697:AEQSU_RS11505
uniprot id: I3YXR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15875
gene id: 746697:AEQSU_RS15875
uniprot id: I3Z078
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

746697:AEQSU RS08040
gene id: 746697:AEQSU_RS08040
uniprot id: I3YVU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

746697:AEQSU RS04145
gene id: 746697:AEQSU_RS04145
uniprot id: I3YTM8
names: Similarity
messages: Belongs to the Skp family.

746697:AEQSU RS05590
gene id: 746697:AEQSU_RS05590
uniprot id: I3YUG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

746697:AEQSU RS04155
gene id: 746697:AEQSU_RS04155
uniprot id: I3YTN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

746697:AEQSU RS00290
gene id: 746697:AEQSU_RS00290
uniprot id: I3YRH3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

746697:AEQSU RS03710
gene id: 746697:AEQSU_RS03710
uniprot id: I3YTE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

746697:AEQSU RS02205
gene id: 746697:AEQSU_RS02205
uniprot id: I3YSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

746697:AEQSU RS00510
gene id: 746697:AEQSU_RS00510
uniprot id: I3YRL5
names: Similarity
messages: Belongs to the SusD family.

746697:AEQSU RS05660
gene id: 746697:AEQSU_RS05660
uniprot id: I3YUH2
names: Similarity
messages: Belongs to the histone deacetylase family.

746697:AEQSU RS05645
gene id: 746697:AEQSU_RS05645
uniprot id: I3YUH0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS15105
gene id: 746697:AEQSU_RS15105
uniprot id: I3YZS3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

746697:AEQSU RS01785
gene id: 746697:AEQSU_RS01785
uniprot id: I3YSB2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

746697:AEQSU RS07500
gene id: 746697:AEQSU_RS07500
uniprot id: I3YVI6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

746697:AEQSU RS12880
gene id: 746697:AEQSU_RS12880
uniprot id: I3YYJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS14205
gene id: 746697:AEQSU_RS14205
uniprot id: I3YZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

746697:AEQSU RS01550
gene id: 746697:AEQSU_RS01550
uniprot id: I3YS66
names: Similarity
messages: Belongs to the NusB family.

746697:AEQSU RS06265
gene id: 746697:AEQSU_RS06265
uniprot id: I3YUU2
names: Similarity
messages: Belongs to the YjiK family.

746697:AEQSU RS15145
gene id: 746697:AEQSU_RS15145
uniprot id: I3YZT1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

746697:AEQSU RS13600
gene id: 746697:AEQSU_RS13600
uniprot id: I3YYY6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

746697:AEQSU RS14620
gene id: 746697:AEQSU_RS14620
uniprot id: I3YZH9
names: Similarity
messages: Belongs to the LOG family.

746697:AEQSU RS03035
gene id: 746697:AEQSU_RS03035
uniprot id: I3YT11
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

746697:AEQSU RS00720
gene id: 746697:AEQSU_RS00720
uniprot id: I3YRQ7
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS14145
gene id: 746697:AEQSU_RS14145
uniprot id: I3YZ87
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

746697:AEQSU RS10350
gene id: 746697:AEQSU_RS10350
uniprot id: I3YX37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

746697:AEQSU RS09265
gene id: 746697:AEQSU_RS09265
uniprot id: I3YWH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

746697:AEQSU RS15435
gene id: 746697:AEQSU_RS15435
uniprot id: I3YZZ0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

746697:AEQSU RS04550
gene id: 746697:AEQSU_RS04550
uniprot id: I3YTV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

746697:AEQSU RS06605
gene id: 746697:AEQSU_RS06605
uniprot id: I3YV09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

746697:AEQSU RS12120
gene id: 746697:AEQSU_RS12120
uniprot id: I3YY37
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

746697:AEQSU RS13650
gene id: 746697:AEQSU_RS13650
uniprot id: I3YYZ5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

746697:AEQSU RS07000
gene id: 746697:AEQSU_RS07000
uniprot id: I3YV89
names: Similarity
messages: Belongs to the HepT RNase toxin family.

746697:AEQSU RS02440
gene id: 746697:AEQSU_RS02440
uniprot id: I3YSP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

746697:AEQSU RS08220
gene id: 746697:AEQSU_RS08220
uniprot id: I3YVX6
names: Similarity
messages: Belongs to the glutamate synthase family.

746697:AEQSU RS05890
gene id: 746697:AEQSU_RS05890
uniprot id: I3YUL8
names: Similarity
messages: Belongs to the GARS family.

746697:AEQSU RS07990
gene id: 746697:AEQSU_RS07990
uniprot id: I3YVT2
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS13380
gene id: 746697:AEQSU_RS13380
uniprot id: I3YYU1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

746697:AEQSU RS03865
gene id: 746697:AEQSU_RS03865
uniprot id: I3YTH5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

746697:AEQSU RS05760
gene id: 746697:AEQSU_RS05760
uniprot id: I3YUJ2
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS09465
gene id: 746697:AEQSU_RS09465
uniprot id: I3YWL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

746697:AEQSU RS12985
gene id: 746697:AEQSU_RS12985
uniprot id: I3YYL1
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS10600
gene id: 746697:AEQSU_RS10600
uniprot id: I3YX87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS07665
gene id: 746697:AEQSU_RS07665
uniprot id: I3YVL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

746697:AEQSU RS11350
gene id: 746697:AEQSU_RS11350
uniprot id: I3YXN7
names: Similarity
messages: Belongs to the Fur family.

746697:AEQSU RS06495
gene id: 746697:AEQSU_RS06495
uniprot id: I3YUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS07750
gene id: 746697:AEQSU_RS07750
uniprot id: I3YVN5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

746697:AEQSU RS12760
gene id: 746697:AEQSU_RS12760
uniprot id: I3YYG6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS02150
gene id: 746697:AEQSU_RS02150
uniprot id: I3YSI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

746697:AEQSU RS00295
gene id: 746697:AEQSU_RS00295
uniprot id: I3YRH4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

746697:AEQSU RS15870
gene id: 746697:AEQSU_RS15870
uniprot id: I3Z077
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS07175
gene id: 746697:AEQSU_RS07175
uniprot id: I3YVC4
names: Similarity
messages: Belongs to the sigma-54 factor family.

746697:AEQSU RS04255
gene id: 746697:AEQSU_RS04255
uniprot id: I3YTQ0
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS04530
gene id: 746697:AEQSU_RS04530
uniprot id: I3YTV5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

746697:AEQSU RS01960
gene id: 746697:AEQSU_RS01960
uniprot id: I3YSE6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

746697:AEQSU RS00175
gene id: 746697:AEQSU_RS00175
uniprot id: I3YRF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

746697:AEQSU RS05970
gene id: 746697:AEQSU_RS05970
uniprot id: I3YUN5
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS08850
gene id: 746697:AEQSU_RS08850
uniprot id: I3YW98
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

746697:AEQSU RS13170
gene id: 746697:AEQSU_RS13170
uniprot id: I3YYP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

746697:AEQSU RS02745
gene id: 746697:AEQSU_RS02745
uniprot id: I3YSV6
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS05650
gene id: 746697:AEQSU_RS05650
uniprot id: I3YUH1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

746697:AEQSU RS09635
gene id: 746697:AEQSU_RS09635
uniprot id: I3YWQ2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

746697:AEQSU RS14430
gene id: 746697:AEQSU_RS14430
uniprot id: I3YZE3
names: Subcellular Location Annotation
messages: Membrane

746697:AEQSU RS08930
gene id: 746697:AEQSU_RS08930
uniprot id: I3YWB4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

746697:AEQSU RS04555
gene id: 746697:AEQSU_RS04555
uniprot id: I3YTW0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

746697:AEQSU RS00725
gene id: 746697:AEQSU_RS00725
uniprot id: I3YRQ8
names: Similarity
messages: Belongs to the universal stress protein A family.

746697:AEQSU RS09235
gene id: 746697:AEQSU_RS09235
uniprot id: I3YWH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS06565
gene id: 746697:AEQSU_RS06565
uniprot id: I3YV01
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

746697:AEQSU RS13185
gene id: 746697:AEQSU_RS13185
uniprot id: I3YYQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS05160
gene id: 746697:AEQSU_RS05160
uniprot id: I3YU74
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

746697:AEQSU RS13845
gene id: 746697:AEQSU_RS13845
uniprot id: I3YZ34
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

746697:AEQSU RS02790
gene id: 746697:AEQSU_RS02790
uniprot id: I3YSW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

746697:AEQSU RS01060
gene id: 746697:AEQSU_RS01060
uniprot id: I3YRX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

746697:AEQSU RS01510
gene id: 746697:AEQSU_RS01510
uniprot id: I3YS57
names: Similarity
messages: Belongs to the 5'-nucleotidase family.