717774:MARME RS11410
gene id: 717774:MARME_RS11410
uniprot id: F2JTK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

717774:MARME RS05690
gene id: 717774:MARME_RS05690
uniprot id: F2JTY0
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

717774:MARME RS00440
gene id: 717774:MARME_RS00440
uniprot id: F2JVD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS21005
gene id: 717774:MARME_RS21005
uniprot id: F2K1P6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

717774:MARME RS06260
gene id: 717774:MARME_RS06260
uniprot id: F2JUU9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

717774:MARME RS17655
gene id: 717774:MARME_RS17655
uniprot id: F2JUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

717774:MARME RS00055
gene id: 717774:MARME_RS00055
uniprot id: F2JUI3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

717774:MARME RS05135
gene id: 717774:MARME_RS05135
uniprot id: F2K4I9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

717774:MARME RS18640
gene id: 717774:MARME_RS18640
uniprot id: F2JW30
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

717774:MARME RS00310
gene id: 717774:MARME_RS00310
uniprot id: F2JVA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS08685
gene id: 717774:MARME_RS08685
uniprot id: F2K0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS01070
gene id: 717774:MARME_RS01070
uniprot id: F2JX00
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

717774:MARME RS18320
gene id: 717774:MARME_RS18320
uniprot id: F2JV97
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

717774:MARME RS03100
gene id: 717774:MARME_RS03100
uniprot id: F2K157
names: Similarity
messages: Belongs to the polysaccharide synthase family.

717774:MARME RS20210
gene id: 717774:MARME_RS20210
uniprot id: F2JZE3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

717774:MARME RS20130
gene id: 717774:MARME_RS20130
uniprot id: F2JZC8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

717774:MARME RS03350
gene id: 717774:MARME_RS03350
uniprot id: F2K1V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

717774:MARME RS01270
gene id: 717774:MARME_RS01270
uniprot id: F2JX36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

717774:MARME RS05790
gene id: 717774:MARME_RS05790
uniprot id: F2JU00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS18990
gene id: 717774:MARME_RS18990
uniprot id: F2JWW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS19145
gene id: 717774:MARME_RS19145
uniprot id: F2JXL9
names: Similarity
messages: Belongs to the hyi family.

717774:MARME RS00785
gene id: 717774:MARME_RS00785
uniprot id: F2JW73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS02400
gene id: 717774:MARME_RS02400
uniprot id: F2JZJ1
names: Similarity
messages: Belongs to the CFA/CMAS family.

717774:MARME RS16250
gene id: 717774:MARME_RS16250
uniprot id: F2K3K6
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

717774:MARME RS22655
gene id: 717774:MARME_RS22655
uniprot id: F2K4J0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

717774:MARME RS06805
gene id: 717774:MARME_RS06805
uniprot id: F2JWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

717774:MARME RS02835
gene id: 717774:MARME_RS02835
uniprot id: F2K0E7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

717774:MARME RS20565
gene id: 717774:MARME_RS20565
uniprot id: F2K079
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

717774:MARME RS03240
gene id: 717774:MARME_RS03240
uniprot id: F2K181
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS16085
gene id: 717774:MARME_RS16085
uniprot id: F2K323
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS00235
gene id: 717774:MARME_RS00235
uniprot id: F2JUL9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS02735
gene id: 717774:MARME_RS02735
uniprot id: F2K0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

717774:MARME RS11995
gene id: 717774:MARME_RS11995
uniprot id: F2JUX1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

717774:MARME RS15530
gene id: 717774:MARME_RS15530
uniprot id: F2K2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

717774:MARME RS17035
gene id: 717774:MARME_RS17035
uniprot id: F2K4W0
names: Similarity
messages: Belongs to the PhzF family.

717774:MARME RS03260
gene id: 717774:MARME_RS03260
uniprot id: F2K183
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

717774:MARME RS06765
gene id: 717774:MARME_RS06765
uniprot id: F2JWE0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717774:MARME RS00355
gene id: 717774:MARME_RS00355
uniprot id: F2JVB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS02865
gene id: 717774:MARME_RS02865
uniprot id: F2K0F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS10425
gene id: 717774:MARME_RS10425
uniprot id: F2K3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

717774:MARME RS10035
gene id: 717774:MARME_RS10035
uniprot id: F2K3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

717774:MARME RS21165
gene id: 717774:MARME_RS21165
uniprot id: F2K1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

717774:MARME RS17490
gene id: 717774:MARME_RS17490
uniprot id: F2JTS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS14830
gene id: 717774:MARME_RS14830
uniprot id: F2K0T4
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

717774:MARME RS05100
gene id: 717774:MARME_RS05100
uniprot id: F2K4I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

717774:MARME RS06915
gene id: 717774:MARME_RS06915
uniprot id: F2JWH0
names: Similarity
messages: Belongs to the elongation factor P family.

717774:MARME RS03620
gene id: 717774:MARME_RS03620
uniprot id: F2K209
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

717774:MARME RS19640
gene id: 717774:MARME_RS19640
uniprot id: F2JYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

717774:MARME RS02140
gene id: 717774:MARME_RS02140
uniprot id: F2JYU7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

717774:MARME RS20030
gene id: 717774:MARME_RS20030
uniprot id: F2JZB1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

717774:MARME RS18120
gene id: 717774:MARME_RS18120
uniprot id: F2JV58
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS18140
gene id: 717774:MARME_RS18140
uniprot id: F2JV62
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

717774:MARME RS20265
gene id: 717774:MARME_RS20265
uniprot id: F2K025
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

717774:MARME RS02275
gene id: 717774:MARME_RS02275
uniprot id: F2JZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

717774:MARME RS17650
gene id: 717774:MARME_RS17650
uniprot id: F2JUA8
names: Similarity
messages: Belongs to the CopC family.

717774:MARME RS05130
gene id: 717774:MARME_RS05130
uniprot id: F2K4I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

717774:MARME RS16220
gene id: 717774:MARME_RS16220
uniprot id: F2K3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

717774:MARME RS03485
gene id: 717774:MARME_RS03485
uniprot id: F2K1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

717774:MARME RS02375
gene id: 717774:MARME_RS02375
uniprot id: F2JZI6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717774:MARME RS02695
gene id: 717774:MARME_RS02695
uniprot id: F2K0B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS04595
gene id: 717774:MARME_RS04595
uniprot id: F2K3T5
names: Similarity
messages: Belongs to the PrpF family.

717774:MARME RS15380
gene id: 717774:MARME_RS15380
uniprot id: F2K2A0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS05285
gene id: 717774:MARME_RS05285
uniprot id: F2JT99
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

717774:MARME RS20485
gene id: 717774:MARME_RS20485
uniprot id: F2K065
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20970
gene id: 717774:MARME_RS20970
uniprot id: F2K123
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS18280
gene id: 717774:MARME_RS18280
uniprot id: F2JV90
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

717774:MARME RS11680
gene id: 717774:MARME_RS11680
uniprot id: F2JU53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

717774:MARME RS09515
gene id: 717774:MARME_RS09515
uniprot id: F2K266
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS14955
gene id: 717774:MARME_RS14955
uniprot id: F2K1G6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

717774:MARME RS16930
gene id: 717774:MARME_RS16930
uniprot id: F2K4T9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

717774:MARME RS21180
gene id: 717774:MARME_RS21180
uniprot id: F2K1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

717774:MARME RS02120
gene id: 717774:MARME_RS02120
uniprot id: F2JYU3
names: Similarity
messages: Belongs to the glutamate synthase family.

717774:MARME RS20890
gene id: 717774:MARME_RS20890
uniprot id: F2K107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

717774:MARME RS18000
gene id: 717774:MARME_RS18000
uniprot id: F2JV39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

717774:MARME RS15150
gene id: 717774:MARME_RS15150
uniprot id: F2K1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

717774:MARME RS03180
gene id: 717774:MARME_RS03180
uniprot id: F2K172
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717774:MARME RS07080
gene id: 717774:MARME_RS07080
uniprot id: F2JX69
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

717774:MARME RS09975
gene id: 717774:MARME_RS09975
uniprot id: F2K2U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

717774:MARME RS05215
gene id: 717774:MARME_RS05215
uniprot id: F2JT86
names: Similarity
messages: Belongs to the TrpC family.

717774:MARME RS14020
gene id: 717774:MARME_RS14020
uniprot id: F2JZ44
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

717774:MARME RS16690
gene id: 717774:MARME_RS16690
uniprot id: F2K492
names: Similarity
messages: Belongs to the UPF0502 family.

717774:MARME RS05850
gene id: 717774:MARME_RS05850
uniprot id: F2JU12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

717774:MARME RS01730
gene id: 717774:MARME_RS01730
uniprot id: F2JXZ5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

717774:MARME RS02525
gene id: 717774:MARME_RS02525
uniprot id: F2JZL6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

717774:MARME RS11920
gene id: 717774:MARME_RS11920
uniprot id: F2JU98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

717774:MARME RS05620
gene id: 717774:MARME_RS05620
uniprot id: F2JTW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

717774:MARME RS10305
gene id: 717774:MARME_RS10305
uniprot id: F2K3F6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS12185
gene id: 717774:MARME_RS12185
uniprot id: F2JV04
names: Similarity
messages: Belongs to the GcvT family.

717774:MARME RS19555
gene id: 717774:MARME_RS19555
uniprot id: F2JYH1
names: Similarity
messages: Belongs to the YoeB family.

717774:MARME RS04050
gene id: 717774:MARME_RS04050
uniprot id: F2K329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS19065
gene id: 717774:MARME_RS19065
uniprot id: F2JWY4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

717774:MARME RS17740
gene id: 717774:MARME_RS17740
uniprot id: F2JUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

717774:MARME RS01470
gene id: 717774:MARME_RS01470
uniprot id: F2JXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS10995
gene id: 717774:MARME_RS10995
uniprot id: F2K4P0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS07795
gene id: 717774:MARME_RS07795
uniprot id: F2JYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

717774:MARME RS16295
gene id: 717774:MARME_RS16295
uniprot id: F2K3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

717774:MARME RS05175
gene id: 717774:MARME_RS05175
uniprot id: F2K4J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

717774:MARME RS00535
gene id: 717774:MARME_RS00535
uniprot id: F2JVF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS01310
gene id: 717774:MARME_RS01310
uniprot id: F2JX44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

717774:MARME RS05540
gene id: 717774:MARME_RS05540
uniprot id: F2JTF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

717774:MARME RS20675
gene id: 717774:MARME_RS20675
uniprot id: F2K0W6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS18110
gene id: 717774:MARME_RS18110
uniprot id: F2JV56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

717774:MARME RS13040
gene id: 717774:MARME_RS13040
uniprot id: F2JWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

717774:MARME RS19770
gene id: 717774:MARME_RS19770
uniprot id: F2JYL3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS07665
gene id: 717774:MARME_RS07665
uniprot id: F2JY55
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS05785
gene id: 717774:MARME_RS05785
uniprot id: F2JTZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS08870
gene id: 717774:MARME_RS08870
uniprot id: F2K0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS11265
gene id: 717774:MARME_RS11265
uniprot id: F2JTH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

717774:MARME RS00755
gene id: 717774:MARME_RS00755
uniprot id: F2JW67
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

717774:MARME RS05165
gene id: 717774:MARME_RS05165
uniprot id: F2K4J5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

717774:MARME RS20465
gene id: 717774:MARME_RS20465
uniprot id: F2K061
names: Similarity
messages: Belongs to the thioesterase family.

717774:MARME RS01300
gene id: 717774:MARME_RS01300
uniprot id: F2JX42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS09095
gene id: 717774:MARME_RS09095
uniprot id: F2K1C8
names: Similarity
messages: Belongs to the MlaA family.

717774:MARME RS11570
gene id: 717774:MARME_RS11570
uniprot id: F2JU31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

717774:MARME RS17310
gene id: 717774:MARME_RS17310
uniprot id: F2JTN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS20215
gene id: 717774:MARME_RS20215
uniprot id: F2K015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

717774:MARME RS00975
gene id: 717774:MARME_RS00975
uniprot id: F2JWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS05005
gene id: 717774:MARME_RS05005
uniprot id: F2K4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

717774:MARME RS04645
gene id: 717774:MARME_RS04645
uniprot id: F2K3U4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS06095
gene id: 717774:MARME_RS06095
uniprot id: F2JUR5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

717774:MARME RS17760
gene id: 717774:MARME_RS17760
uniprot id: F2JUC9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS01680
gene id: 717774:MARME_RS01680
uniprot id: F2JXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS12575
gene id: 717774:MARME_RS12575
uniprot id: F2JVU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

717774:MARME RS05760
gene id: 717774:MARME_RS05760
uniprot id: F2JTZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS01195
gene id: 717774:MARME_RS01195
uniprot id: F2JX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

717774:MARME RS02510
gene id: 717774:MARME_RS02510
uniprot id: F2JZL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

717774:MARME RS04975
gene id: 717774:MARME_RS04975
uniprot id: F2K4F7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

717774:MARME RS18920
gene id: 717774:MARME_RS18920
uniprot id: F2JWV5
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS20780
gene id: 717774:MARME_RS20780
uniprot id: F2K0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS11925
gene id: 717774:MARME_RS11925
uniprot id: F2JU99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS18645
gene id: 717774:MARME_RS18645
uniprot id: F2JW31
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS01305
gene id: 717774:MARME_RS01305
uniprot id: F2JX43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

717774:MARME RS18130
gene id: 717774:MARME_RS18130
uniprot id: F2JV60
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

717774:MARME RS07600
gene id: 717774:MARME_RS07600
uniprot id: F2JY43
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

717774:MARME RS18845
gene id: 717774:MARME_RS18845
uniprot id: F2JWU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

717774:MARME RS13120
gene id: 717774:MARME_RS13120
uniprot id: F2JXE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS02940
gene id: 717774:MARME_RS02940
uniprot id: F2K133
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

717774:MARME RS05950
gene id: 717774:MARME_RS05950
uniprot id: F2JUN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS09915
gene id: 717774:MARME_RS09915
uniprot id: F2K2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

717774:MARME RS05585
gene id: 717774:MARME_RS05585
uniprot id: F2JTV8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

717774:MARME RS08200
gene id: 717774:MARME_RS08200
uniprot id: F2JZM7
names: Similarity
messages: Belongs to the FGGY kinase family.

717774:MARME RS20845
gene id: 717774:MARME_RS20845
uniprot id: F2K0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS06020
gene id: 717774:MARME_RS06020
uniprot id: F2JUQ0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

717774:MARME RS21030
gene id: 717774:MARME_RS21030
uniprot id: F2K1Q1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS05860
gene id: 717774:MARME_RS05860
uniprot id: F2JU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

717774:MARME RS16845
gene id: 717774:MARME_RS16845
uniprot id: F2K4C4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

717774:MARME RS01280
gene id: 717774:MARME_RS01280
uniprot id: F2JX38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

717774:MARME RS16435
gene id: 717774:MARME_RS16435
uniprot id: F2K3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

717774:MARME RS07635
gene id: 717774:MARME_RS07635
uniprot id: F2JY50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS13545
gene id: 717774:MARME_RS13545
uniprot id: F2JY94
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

717774:MARME RS15555
gene id: 717774:MARME_RS15555
uniprot id: F2K2D3
names: Similarity
messages: Belongs to the GARS family.

717774:MARME RS21160
gene id: 717774:MARME_RS21160
uniprot id: F2K1S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

717774:MARME RS13590
gene id: 717774:MARME_RS13590
uniprot id: F2JYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS14965
gene id: 717774:MARME_RS14965
uniprot id: F2K1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

717774:MARME RS01485
gene id: 717774:MARME_RS01485
uniprot id: F2JXU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

717774:MARME RS08230
gene id: 717774:MARME_RS08230
uniprot id: F2JZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS05050
gene id: 717774:MARME_RS05050
uniprot id: F2K4H2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

717774:MARME RS04635
gene id: 717774:MARME_RS04635
uniprot id: F2K3U3
names: Subcellular Location Annotation
messages: nucleolus

717774:MARME RS20225
gene id: 717774:MARME_RS20225
uniprot id: F2K017
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

717774:MARME RS07370
gene id: 717774:MARME_RS07370
uniprot id: F2JXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

717774:MARME RS07915
gene id: 717774:MARME_RS07915
uniprot id: F2JYV9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

717774:MARME RS09520
gene id: 717774:MARME_RS09520
uniprot id: F2K267
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS06145
gene id: 717774:MARME_RS06145
uniprot id: F2JUS5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

717774:MARME RS16370
gene id: 717774:MARME_RS16370
uniprot id: F2K3N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS01035
gene id: 717774:MARME_RS01035
uniprot id: F2JWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS18765
gene id: 717774:MARME_RS18765
uniprot id: F2JWS8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

717774:MARME RS04280
gene id: 717774:MARME_RS04280
uniprot id: F2K369
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

717774:MARME RS00025
gene id: 717774:MARME_RS00025
uniprot id: F2JUH7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

717774:MARME RS05230
gene id: 717774:MARME_RS05230
uniprot id: F2JT88
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

717774:MARME RS07960
gene id: 717774:MARME_RS07960
uniprot id: F2JYW8
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS14900
gene id: 717774:MARME_RS14900
uniprot id: F2K0U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

717774:MARME RS14285
gene id: 717774:MARME_RS14285
uniprot id: F2JZV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS05410
gene id: 717774:MARME_RS05410
uniprot id: F2JTC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

717774:MARME RS14365
gene id: 717774:MARME_RS14365
uniprot id: F2JZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS15725
gene id: 717774:MARME_RS15725
uniprot id: F2K2V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

717774:MARME RS12560
gene id: 717774:MARME_RS12560
uniprot id: F2JVU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

717774:MARME RS17370
gene id: 717774:MARME_RS17370
uniprot id: F2JTQ0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS15900
gene id: 717774:MARME_RS15900
uniprot id: F2K2Z2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

717774:MARME RS18690
gene id: 717774:MARME_RS18690
uniprot id: F2JW40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS08535
gene id: 717774:MARME_RS08535
uniprot id: F2K0G2
names: Similarity
messages: Belongs to the GcvT family.

717774:MARME RS14580
gene id: 717774:MARME_RS14580
uniprot id: F2K0N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

717774:MARME RS10875
gene id: 717774:MARME_RS10875
uniprot id: F2K4L6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

717774:MARME RS00175
gene id: 717774:MARME_RS00175
uniprot id: F2JUK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS05830
gene id: 717774:MARME_RS05830
uniprot id: F2JU08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

717774:MARME RS12885
gene id: 717774:MARME_RS12885
uniprot id: F2JWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

717774:MARME RS10465
gene id: 717774:MARME_RS10465
uniprot id: F2K3Y8
names: Similarity
messages: Belongs to the MotB family.

717774:MARME RS05415
gene id: 717774:MARME_RS05415
uniprot id: F2JTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

717774:MARME RS04965
gene id: 717774:MARME_RS04965
uniprot id: F2K4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

717774:MARME RS11495
gene id: 717774:MARME_RS11495
uniprot id: F2JTL9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

717774:MARME RS10225
gene id: 717774:MARME_RS10225
uniprot id: F2K3E0
names: Similarity
messages: Belongs to the GSP E family.

717774:MARME RS07980
gene id: 717774:MARME_RS07980
uniprot id: F2JYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

717774:MARME RS01455
gene id: 717774:MARME_RS01455
uniprot id: F2JXU2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

717774:MARME RS04225
gene id: 717774:MARME_RS04225
uniprot id: F2K358
names: Similarity
messages: Belongs to the PrpF family.

717774:MARME RS16735
gene id: 717774:MARME_RS16735
uniprot id: F2K4A2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

717774:MARME RS05935
gene id: 717774:MARME_RS05935
uniprot id: F2JUN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

717774:MARME RS01355
gene id: 717774:MARME_RS01355
uniprot id: F2JX53
names: Similarity
messages: Belongs to the DinB family.

717774:MARME RS05115
gene id: 717774:MARME_RS05115
uniprot id: F2K4I5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

717774:MARME RS20170
gene id: 717774:MARME_RS20170
uniprot id: F2JZD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

717774:MARME RS05695
gene id: 717774:MARME_RS05695
uniprot id: F2JTY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS04290
gene id: 717774:MARME_RS04290
uniprot id: F2K371
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

717774:MARME RS02820
gene id: 717774:MARME_RS02820
uniprot id: F2K0E4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS16710
gene id: 717774:MARME_RS16710
uniprot id: F2K496
names: Similarity
messages: Belongs to the pirin family.

717774:MARME RS10905
gene id: 717774:MARME_RS10905
uniprot id: F2K4M2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

717774:MARME RS12350
gene id: 717774:MARME_RS12350
uniprot id: F2JVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS09600
gene id: 717774:MARME_RS09600
uniprot id: F2K281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS12955
gene id: 717774:MARME_RS12955
uniprot id: F2JWP4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

717774:MARME RS16980
gene id: 717774:MARME_RS16980
uniprot id: F2K4U9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

717774:MARME RS12740
gene id: 717774:MARME_RS12740
uniprot id: F2JWK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

717774:MARME RS00140
gene id: 717774:MARME_RS00140
uniprot id: F2JUK0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

717774:MARME RS09635
gene id: 717774:MARME_RS09635
uniprot id: F2K288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

717774:MARME RS18215
gene id: 717774:MARME_RS18215
uniprot id: F2JV77
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS00735
gene id: 717774:MARME_RS00735
uniprot id: F2JW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

717774:MARME RS20450
gene id: 717774:MARME_RS20450
uniprot id: F2K060
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717774:MARME RS14235
gene id: 717774:MARME_RS14235
uniprot id: F2JZU7
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

717774:MARME RS13805
gene id: 717774:MARME_RS13805
uniprot id: F2JYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS20865
gene id: 717774:MARME_RS20865
uniprot id: F2K102
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS01555
gene id: 717774:MARME_RS01555
uniprot id: F2JXV9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS01190
gene id: 717774:MARME_RS01190
uniprot id: F2JX20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

717774:MARME RS11500
gene id: 717774:MARME_RS11500
uniprot id: F2JTM0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

717774:MARME RS19465
gene id: 717774:MARME_RS19465
uniprot id: F2JXT4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

717774:MARME RS04530
gene id: 717774:MARME_RS04530
uniprot id: F2K3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS13910
gene id: 717774:MARME_RS13910
uniprot id: F2JZ22
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS15815
gene id: 717774:MARME_RS15815
uniprot id: F2K2X5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

717774:MARME RS11485
gene id: 717774:MARME_RS11485
uniprot id: F2JTL7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

717774:MARME RS14030
gene id: 717774:MARME_RS14030
uniprot id: F2JZ46
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

717774:MARME RS19025
gene id: 717774:MARME_RS19025
uniprot id: F2JWX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

717774:MARME RS00635
gene id: 717774:MARME_RS00635
uniprot id: F2JVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

717774:MARME RS18780
gene id: 717774:MARME_RS18780
uniprot id: F2JWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

717774:MARME RS01330
gene id: 717774:MARME_RS01330
uniprot id: F2JX48
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

717774:MARME RS17800
gene id: 717774:MARME_RS17800
uniprot id: F2JUD7
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

717774:MARME RS16070
gene id: 717774:MARME_RS16070
uniprot id: F2K320
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS10110
gene id: 717774:MARME_RS10110
uniprot id: F2K3B7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

717774:MARME RS01210
gene id: 717774:MARME_RS01210
uniprot id: F2JX24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS07620
gene id: 717774:MARME_RS07620
uniprot id: F2JY47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

717774:MARME RS08780
gene id: 717774:MARME_RS08780
uniprot id: F2K0L0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

717774:MARME RS05780
gene id: 717774:MARME_RS05780
uniprot id: F2JTZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

717774:MARME RS04475
gene id: 717774:MARME_RS04475
uniprot id: F2K3R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS06470
gene id: 717774:MARME_RS06470
uniprot id: F2JVL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS18635
gene id: 717774:MARME_RS18635
uniprot id: F2JW28
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

717774:MARME RS16405
gene id: 717774:MARME_RS16405
uniprot id: F2K3N7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

717774:MARME RS01160
gene id: 717774:MARME_RS01160
uniprot id: F2JX14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

717774:MARME RS10375
gene id: 717774:MARME_RS10375
uniprot id: F2K3H0
names: Similarity
messages: Belongs to the UPF0234 family.

717774:MARME RS00490
gene id: 717774:MARME_RS00490
uniprot id: F2JVE6
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

717774:MARME RS03365
gene id: 717774:MARME_RS03365
uniprot id: F2K1V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: Belongs to the bacterial reverse transcriptase family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

717774:MARME RS04045
gene id: 717774:MARME_RS04045
uniprot id: F2K328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS20275
gene id: 717774:MARME_RS20275
uniprot id: F2K027
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS17595
gene id: 717774:MARME_RS17595
uniprot id: F2JTU5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS12580
gene id: 717774:MARME_RS12580
uniprot id: F2JVU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

717774:MARME RS06210
gene id: 717774:MARME_RS06210
uniprot id: F2JUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

717774:MARME RS19185
gene id: 717774:MARME_RS19185
uniprot id: F2JXM7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS11750
gene id: 717774:MARME_RS11750
uniprot id: F2JU67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

717774:MARME RS17190
gene id: 717774:MARME_RS17190
uniprot id: F2K4Z1
names: Similarity
messages: Belongs to the pyruvate kinase family.

717774:MARME RS10140
gene id: 717774:MARME_RS10140
uniprot id: F2K3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

717774:MARME RS20435
gene id: 717774:MARME_RS20435
uniprot id: F2K057
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS16645
gene id: 717774:MARME_RS16645
uniprot id: F2K483
names: Similarity
messages: Belongs to the UDPGP type 2 family.

717774:MARME RS01225
gene id: 717774:MARME_RS01225
uniprot id: F2JX27
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

717774:MARME RS07485
gene id: 717774:MARME_RS07485
uniprot id: F2JY21
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

717774:MARME RS00740
gene id: 717774:MARME_RS00740
uniprot id: F2JW64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

717774:MARME RS19190
gene id: 717774:MARME_RS19190
uniprot id: F2JXM9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS13010
gene id: 717774:MARME_RS13010
uniprot id: F2JWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

717774:MARME RS18185
gene id: 717774:MARME_RS18185
uniprot id: F2JV71
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

717774:MARME RS02925
gene id: 717774:MARME_RS02925
uniprot id: F2K130
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

717774:MARME RS02600
gene id: 717774:MARME_RS02600
uniprot id: F2K099
names: Similarity
messages: Belongs to the BMP lipoprotein family.

717774:MARME RS14460
gene id: 717774:MARME_RS14460
uniprot id: F2JZZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717774:MARME RS09965
gene id: 717774:MARME_RS09965
uniprot id: F2K2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

717774:MARME RS18155
gene id: 717774:MARME_RS18155
uniprot id: F2JV65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

717774:MARME RS05590
gene id: 717774:MARME_RS05590
uniprot id: F2JTV9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

717774:MARME RS11760
gene id: 717774:MARME_RS11760
uniprot id: F2JU69
names: Similarity
messages: Belongs to the UPF0102 family.

717774:MARME RS00850
gene id: 717774:MARME_RS00850
uniprot id: F2JW86
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS08765
gene id: 717774:MARME_RS08765
uniprot id: F2K0K7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS20175
gene id: 717774:MARME_RS20175
uniprot id: F2JZD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS20550
gene id: 717774:MARME_RS20550
uniprot id: F2K076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS10090
gene id: 717774:MARME_RS10090
uniprot id: F2K3B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

717774:MARME RS01925
gene id: 717774:MARME_RS01925
uniprot id: F2JYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

717774:MARME RS16555
gene id: 717774:MARME_RS16555
uniprot id: F2K465
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

717774:MARME RS21170
gene id: 717774:MARME_RS21170
uniprot id: F2K1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

717774:MARME RS15905
gene id: 717774:MARME_RS15905
uniprot id: F2K2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

717774:MARME RS19925
gene id: 717774:MARME_RS19925
uniprot id: F2JZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS06195
gene id: 717774:MARME_RS06195
uniprot id: F2JUT5
names: Similarity
messages: Belongs to the YfgM family.

717774:MARME RS09085
gene id: 717774:MARME_RS09085
uniprot id: F2K1C6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

717774:MARME RS16075
gene id: 717774:MARME_RS16075
uniprot id: F2K321
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

717774:MARME RS05200
gene id: 717774:MARME_RS05200
uniprot id: F2JT83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

717774:MARME RS05965
gene id: 717774:MARME_RS05965
uniprot id: F2JUN9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

717774:MARME RS20255
gene id: 717774:MARME_RS20255
uniprot id: F2K023
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

717774:MARME RS15220
gene id: 717774:MARME_RS15220
uniprot id: F2K1L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

717774:MARME RS00445
gene id: 717774:MARME_RS00445
uniprot id: F2JVD6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

717774:MARME RS02675
gene id: 717774:MARME_RS02675
uniprot id: F2K0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

717774:MARME RS08840
gene id: 717774:MARME_RS08840
uniprot id: F2K0M3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

717774:MARME RS10685
gene id: 717774:MARME_RS10685
uniprot id: F2K429
names: Caution
names: Function
names: Similarity
messages: As this bacterium is not an Enterobacterale, this protein may not have a true dGTPase activity.
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

717774:MARME RS14180
gene id: 717774:MARME_RS14180
uniprot id: F2JZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

717774:MARME RS01215
gene id: 717774:MARME_RS01215
uniprot id: F2JX25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

717774:MARME RS09020
gene id: 717774:MARME_RS09020
uniprot id: F2K1B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

717774:MARME RS16245
gene id: 717774:MARME_RS16245
uniprot id: F2K3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

717774:MARME RS18875
gene id: 717774:MARME_RS18875
uniprot id: F2JWV1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

717774:MARME RS06830
gene id: 717774:MARME_RS06830
uniprot id: F2JWF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS17015
gene id: 717774:MARME_RS17015
uniprot id: F2K4V6
names: Similarity
messages: Belongs to the P(II) protein family.

717774:MARME RS01290
gene id: 717774:MARME_RS01290
uniprot id: F2JX40
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

717774:MARME RS03820
gene id: 717774:MARME_RS03820
uniprot id: F2K2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

717774:MARME RS02955
gene id: 717774:MARME_RS02955
uniprot id: F2K136
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

717774:MARME RS09055
gene id: 717774:MARME_RS09055
uniprot id: F2K1C0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

717774:MARME RS19030
gene id: 717774:MARME_RS19030
uniprot id: F2JWX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

717774:MARME RS14810
gene id: 717774:MARME_RS14810
uniprot id: F2K0S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

717774:MARME RS20085
gene id: 717774:MARME_RS20085
uniprot id: F2JZC2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS11800
gene id: 717774:MARME_RS11800
uniprot id: F2JU77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

717774:MARME RS21550
gene id: 717774:MARME_RS21550
uniprot id: F2JZ71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

717774:MARME RS13850
gene id: 717774:MARME_RS13850
uniprot id: F2JZ10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

717774:MARME RS05085
gene id: 717774:MARME_RS05085
uniprot id: F2K4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

717774:MARME RS11590
gene id: 717774:MARME_RS11590
uniprot id: F2JU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS12680
gene id: 717774:MARME_RS12680
uniprot id: F2JVW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS19755
gene id: 717774:MARME_RS19755
uniprot id: F2JYL0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS19560
gene id: 717774:MARME_RS19560
uniprot id: F2JYH2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

717774:MARME RS05110
gene id: 717774:MARME_RS05110
uniprot id: F2K4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

717774:MARME RS13050
gene id: 717774:MARME_RS13050
uniprot id: F2JWR2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS01165
gene id: 717774:MARME_RS01165
uniprot id: F2JX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

717774:MARME RS01785
gene id: 717774:MARME_RS01785
uniprot id: F2JY05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS04625
gene id: 717774:MARME_RS04625
uniprot id: F2K3U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS04765
gene id: 717774:MARME_RS04765
uniprot id: F2K3W7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS02170
gene id: 717774:MARME_RS02170
uniprot id: F2JZE6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS05080
gene id: 717774:MARME_RS05080
uniprot id: F2K4H8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

717774:MARME RS00705
gene id: 717774:MARME_RS00705
uniprot id: F2JW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS04865
gene id: 717774:MARME_RS04865
uniprot id: F2K4D7
names: Similarity
messages: Belongs to the thioesterase family.

717774:MARME RS06450
gene id: 717774:MARME_RS06450
uniprot id: F2JVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS11345
gene id: 717774:MARME_RS11345
uniprot id: F2JTI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

717774:MARME RS12590
gene id: 717774:MARME_RS12590
uniprot id: F2JVV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS06725
gene id: 717774:MARME_RS06725
uniprot id: F2JWD2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

717774:MARME RS03865
gene id: 717774:MARME_RS03865
uniprot id: F2K2K0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

717774:MARME RS05985
gene id: 717774:MARME_RS05985
uniprot id: F2JUP3
names: Similarity
messages: Belongs to the Smp family.

717774:MARME RS16975
gene id: 717774:MARME_RS16975
uniprot id: F2K4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

717774:MARME RS18600
gene id: 717774:MARME_RS18600
uniprot id: F2JW21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

717774:MARME RS01595
gene id: 717774:MARME_RS01595
uniprot id: F2JXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

717774:MARME RS15710
gene id: 717774:MARME_RS15710
uniprot id: F2K2G4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS18695
gene id: 717774:MARME_RS18695
uniprot id: F2JW41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS17150
gene id: 717774:MARME_RS17150
uniprot id: F2K4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS06035
gene id: 717774:MARME_RS06035
uniprot id: F2JUQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS03245
gene id: 717774:MARME_RS03245
uniprot id: F2K182
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

717774:MARME RS06305
gene id: 717774:MARME_RS06305
uniprot id: F2JUV8
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20735
gene id: 717774:MARME_RS20735
uniprot id: F2K0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

717774:MARME RS10125
gene id: 717774:MARME_RS10125
uniprot id: F2K3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS04500
gene id: 717774:MARME_RS04500
uniprot id: F2K3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS05030
gene id: 717774:MARME_RS05030
uniprot id: F2K4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS10280
gene id: 717774:MARME_RS10280
uniprot id: F2K3F1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

717774:MARME RS00410
gene id: 717774:MARME_RS00410
uniprot id: F2JVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS13390
gene id: 717774:MARME_RS13390
uniprot id: F2JXJ3
names: Activity Regulation
names: Cofactor
names: Function
names: Induction
names: Miscellaneous
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Contains 1 cysteine tryptophylquinone per subunit.
messages: Forms part of an operon with lodB.
messages: Has antibacterial activity against a wide spectrum of Gram-positive and Gram-negative bacteria including nosocomial isolates of S.aureus and Pseudomonas sp. The antimicrobial activity is due to hydrogen peroxide generated by its lysine oxidase activity. Also has autotoxic activity. Involved in biofilm differentiation; responsible for cell death within microcolonies during biofilm development which is linked to the generation of a phenotypically diverse dispersal population and thus may play a role in colonization.
messages: Homotetramer.
messages: Inhibited by aminoguanidine, amiloride and beta-aminopropionitrile.
messages: Secreted
messages: The cysteine tryptophylquinone (CTQ) is generated by oxidation of the indole ring of a tryptophan residue to form tryptophylquinone, followed by covalent cross-linking with a cysteine residue.
messages: The intracellular stability of LodA is dependent on the presence of LodB protein.

717774:MARME RS15665
gene id: 717774:MARME_RS15665
uniprot id: F2K2F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

717774:MARME RS16615
gene id: 717774:MARME_RS16615
uniprot id: F2K477
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

717774:MARME RS05065
gene id: 717774:MARME_RS05065
uniprot id: F2K4H5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS18750
gene id: 717774:MARME_RS18750
uniprot id: F2JWS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS17365
gene id: 717774:MARME_RS17365
uniprot id: F2JTP9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

717774:MARME RS01275
gene id: 717774:MARME_RS01275
uniprot id: F2JX37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

717774:MARME RS02965
gene id: 717774:MARME_RS02965
uniprot id: F2K138
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

717774:MARME RS07455
gene id: 717774:MARME_RS07455
uniprot id: F2JY15
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

717774:MARME RS14840
gene id: 717774:MARME_RS14840
uniprot id: F2K0T6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

717774:MARME RS08820
gene id: 717774:MARME_RS08820
uniprot id: F2K0L9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

717774:MARME RS05685
gene id: 717774:MARME_RS05685
uniprot id: F2JTX9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS07245
gene id: 717774:MARME_RS07245
uniprot id: F2JXA3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

717774:MARME RS05055
gene id: 717774:MARME_RS05055
uniprot id: F2K4H3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

717774:MARME RS19450
gene id: 717774:MARME_RS19450
uniprot id: F2JXT1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS18255
gene id: 717774:MARME_RS18255
uniprot id: F2JV85
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

717774:MARME RS16040
gene id: 717774:MARME_RS16040
uniprot id: F2K314
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

717774:MARME RS15135
gene id: 717774:MARME_RS15135
uniprot id: F2K1K2
names: Similarity
messages: Belongs to the peptidase S41A family.

717774:MARME RS03320
gene id: 717774:MARME_RS03320
uniprot id: F2K1V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

717774:MARME RS08635
gene id: 717774:MARME_RS08635
uniprot id: F2K0I1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

717774:MARME RS02910
gene id: 717774:MARME_RS02910
uniprot id: F2K127
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS00365
gene id: 717774:MARME_RS00365
uniprot id: F2JVC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS20185
gene id: 717774:MARME_RS20185
uniprot id: F2JZD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

717774:MARME RS12640
gene id: 717774:MARME_RS12640
uniprot id: F2JVW0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

717774:MARME RS05580
gene id: 717774:MARME_RS05580
uniprot id: F2JTV7
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

717774:MARME RS17075
gene id: 717774:MARME_RS17075
uniprot id: F2K4W8
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

717774:MARME RS01795
gene id: 717774:MARME_RS01795
uniprot id: F2JYN1
names: Similarity
messages: Belongs to the class-I fumarase family.

717774:MARME RS09035
gene id: 717774:MARME_RS09035
uniprot id: F2K1B6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

717774:MARME RS20305
gene id: 717774:MARME_RS20305
uniprot id: F2K033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS04080
gene id: 717774:MARME_RS04080
uniprot id: F2K335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS19325
gene id: 717774:MARME_RS19325
uniprot id: F2JXQ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS10495
gene id: 717774:MARME_RS10495
uniprot id: F2K3Z4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

717774:MARME RS15540
gene id: 717774:MARME_RS15540
uniprot id: F2K2D0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

717774:MARME RS04200
gene id: 717774:MARME_RS04200
uniprot id: F2K353
names: Similarity
messages: Belongs to the GST superfamily.

717774:MARME RS09715
gene id: 717774:MARME_RS09715
uniprot id: F2K2P9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

717774:MARME RS12750
gene id: 717774:MARME_RS12750
uniprot id: F2JWK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS20080
gene id: 717774:MARME_RS20080
uniprot id: F2JZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS09895
gene id: 717774:MARME_RS09895
uniprot id: F2K2T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

717774:MARME RS18995
gene id: 717774:MARME_RS18995
uniprot id: F2JWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS10445
gene id: 717774:MARME_RS10445
uniprot id: F2K3Y4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS02530
gene id: 717774:MARME_RS02530
uniprot id: F2JZL7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

717774:MARME RS12795
gene id: 717774:MARME_RS12795
uniprot id: F2JWL3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

717774:MARME RS13875
gene id: 717774:MARME_RS13875
uniprot id: F2JZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

717774:MARME RS07165
gene id: 717774:MARME_RS07165
uniprot id: F2JX87
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS10845
gene id: 717774:MARME_RS10845
uniprot id: F2K4L0
names: Similarity
messages: Belongs to the BolA/IbaG family.

717774:MARME RS19110
gene id: 717774:MARME_RS19110
uniprot id: F2JXL2
names: Similarity
messages: Belongs to the glutamine synthetase family.

717774:MARME RS14160
gene id: 717774:MARME_RS14160
uniprot id: F2JZ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

717774:MARME RS12645
gene id: 717774:MARME_RS12645
uniprot id: F2JVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

717774:MARME RS06060
gene id: 717774:MARME_RS06060
uniprot id: F2JUQ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717774:MARME RS11350
gene id: 717774:MARME_RS11350
uniprot id: F2JTJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS13230
gene id: 717774:MARME_RS13230
uniprot id: F2JXG1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS21185
gene id: 717774:MARME_RS21185
uniprot id: F2K1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

717774:MARME RS10350
gene id: 717774:MARME_RS10350
uniprot id: F2K3G5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

717774:MARME RS11725
gene id: 717774:MARME_RS11725
uniprot id: F2JU62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS21565
gene id: 717774:MARME_RS21565
uniprot id: F2K2W8
names: Similarity
messages: Belongs to the MipA/OmpV family.

717774:MARME RS06930
gene id: 717774:MARME_RS06930
uniprot id: F2JWH3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

717774:MARME RS03720
gene id: 717774:MARME_RS03720
uniprot id: F2K2H8
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS15020
gene id: 717774:MARME_RS15020
uniprot id: F2K1H9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS07605
gene id: 717774:MARME_RS07605
uniprot id: F2JY44
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

717774:MARME RS03450
gene id: 717774:MARME_RS03450
uniprot id: F2K1X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

717774:MARME RS11845
gene id: 717774:MARME_RS11845
uniprot id: F2JU85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS16185
gene id: 717774:MARME_RS16185
uniprot id: F2K3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

717774:MARME RS02795
gene id: 717774:MARME_RS02795
uniprot id: F2K0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

717774:MARME RS01005
gene id: 717774:MARME_RS01005
uniprot id: F2JWB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

717774:MARME RS13150
gene id: 717774:MARME_RS13150
uniprot id: F2JXE6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS02870
gene id: 717774:MARME_RS02870
uniprot id: F2K0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS12265
gene id: 717774:MARME_RS12265
uniprot id: F2JV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS07610
gene id: 717774:MARME_RS07610
uniprot id: F2JY45
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

717774:MARME RS17280
gene id: 717774:MARME_RS17280
uniprot id: F2JTN2
names: Similarity
messages: Belongs to the P(II) protein family.

717774:MARME RS13755
gene id: 717774:MARME_RS13755
uniprot id: F2JYD6
names: Similarity
messages: Belongs to the group II decarboxylase family.

717774:MARME RS03770
gene id: 717774:MARME_RS03770
uniprot id: F2K2I8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

717774:MARME RS05930
gene id: 717774:MARME_RS05930
uniprot id: F2JUN2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16755
gene id: 717774:MARME_RS16755
uniprot id: F2K4A6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

717774:MARME RS07440
gene id: 717774:MARME_RS07440
uniprot id: F2JY12
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

717774:MARME RS09140
gene id: 717774:MARME_RS09140
uniprot id: F2K1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

717774:MARME RS12585
gene id: 717774:MARME_RS12585
uniprot id: F2JVU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

717774:MARME RS19805
gene id: 717774:MARME_RS19805
uniprot id: F2JYM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS03615
gene id: 717774:MARME_RS03615
uniprot id: F2K208
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

717774:MARME RS08955
gene id: 717774:MARME_RS08955
uniprot id: F2K1A0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717774:MARME RS00695
gene id: 717774:MARME_RS00695
uniprot id: F2JW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

717774:MARME RS04435
gene id: 717774:MARME_RS04435
uniprot id: F2K3Q2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

717774:MARME RS21245
gene id: 717774:MARME_RS21245
uniprot id: F2JVF6
names: Similarity
messages: Belongs to the peptidase S8 family.

717774:MARME RS08335
gene id: 717774:MARME_RS08335
uniprot id: F2JZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS16630
gene id: 717774:MARME_RS16630
uniprot id: F2K480
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

717774:MARME RS05045
gene id: 717774:MARME_RS05045
uniprot id: F2K4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS02440
gene id: 717774:MARME_RS02440
uniprot id: F2JZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

717774:MARME RS01660
gene id: 717774:MARME_RS01660
uniprot id: F2JXY1
names: Similarity
messages: Belongs to the SfsA family.

717774:MARME RS04955
gene id: 717774:MARME_RS04955
uniprot id: F2K4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

717774:MARME RS10260
gene id: 717774:MARME_RS10260
uniprot id: F2K3E7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

717774:MARME RS12875
gene id: 717774:MARME_RS12875
uniprot id: F2JWM9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

717774:MARME RS07590
gene id: 717774:MARME_RS07590
uniprot id: F2JY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS17210
gene id: 717774:MARME_RS17210
uniprot id: F2K4Z5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

717774:MARME RS16275
gene id: 717774:MARME_RS16275
uniprot id: F2K3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

717774:MARME RS07940
gene id: 717774:MARME_RS07940
uniprot id: F2JYW4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS09695
gene id: 717774:MARME_RS09695
uniprot id: F2K2P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

717774:MARME RS10470
gene id: 717774:MARME_RS10470
uniprot id: F2K3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

717774:MARME RS06110
gene id: 717774:MARME_RS06110
uniprot id: F2JUR8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

717774:MARME RS20995
gene id: 717774:MARME_RS20995
uniprot id: F2K1P3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

717774:MARME RS08850
gene id: 717774:MARME_RS08850
uniprot id: F2K0M5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS14605
gene id: 717774:MARME_RS14605
uniprot id: F2K0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

717774:MARME RS05705
gene id: 717774:MARME_RS05705
uniprot id: F2JTY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

717774:MARME RS17345
gene id: 717774:MARME_RS17345
uniprot id: F2JTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

717774:MARME RS07360
gene id: 717774:MARME_RS07360
uniprot id: F2JXC6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

717774:MARME RS03845
gene id: 717774:MARME_RS03845
uniprot id: F2K2J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12025
gene id: 717774:MARME_RS12025
uniprot id: F2JUX6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS11285
gene id: 717774:MARME_RS11285
uniprot id: F2JTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

717774:MARME RS05335
gene id: 717774:MARME_RS05335
uniprot id: F2JTA9
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

717774:MARME RS20810
gene id: 717774:MARME_RS20810
uniprot id: F2K0Z3
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

717774:MARME RS18620
gene id: 717774:MARME_RS18620
uniprot id: F2JW25
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

717774:MARME RS20200
gene id: 717774:MARME_RS20200
uniprot id: F2JZE1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

717774:MARME RS15065
gene id: 717774:MARME_RS15065
uniprot id: F2K1I8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717774:MARME RS02545
gene id: 717774:MARME_RS02545
uniprot id: F2K088
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

717774:MARME RS02535
gene id: 717774:MARME_RS02535
uniprot id: F2JZL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

717774:MARME RS06295
gene id: 717774:MARME_RS06295
uniprot id: F2JUV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS03950
gene id: 717774:MARME_RS03950
uniprot id: F2K2L7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

717774:MARME RS00680
gene id: 717774:MARME_RS00680
uniprot id: F2JW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS20850
gene id: 717774:MARME_RS20850
uniprot id: F2K0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717774:MARME RS19265
gene id: 717774:MARME_RS19265
uniprot id: F2JXP3
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

717774:MARME RS17805
gene id: 717774:MARME_RS17805
uniprot id: F2JUD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS18605
gene id: 717774:MARME_RS18605
uniprot id: F2JW22
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

717774:MARME RS09670
gene id: 717774:MARME_RS09670
uniprot id: F2K2P0
names: Similarity
messages: Belongs to the YjdM family.

717774:MARME RS01895
gene id: 717774:MARME_RS01895
uniprot id: F2JYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS13105
gene id: 717774:MARME_RS13105
uniprot id: F2JXD7
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

717774:MARME RS10390
gene id: 717774:MARME_RS10390
uniprot id: F2K3H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

717774:MARME RS14130
gene id: 717774:MARME_RS14130
uniprot id: F2JZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

717774:MARME RS16840
gene id: 717774:MARME_RS16840
uniprot id: F2K4C3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

717774:MARME RS05645
gene id: 717774:MARME_RS05645
uniprot id: F2JTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

717774:MARME RS10435
gene id: 717774:MARME_RS10435
uniprot id: F2K3Y2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

717774:MARME RS18405
gene id: 717774:MARME_RS18405
uniprot id: F2JVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS16530
gene id: 717774:MARME_RS16530
uniprot id: F2K460
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

717774:MARME RS12880
gene id: 717774:MARME_RS12880
uniprot id: F2JWN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

717774:MARME RS15515
gene id: 717774:MARME_RS15515
uniprot id: F2K2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS16950
gene id: 717774:MARME_RS16950
uniprot id: F2K4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

717774:MARME RS16860
gene id: 717774:MARME_RS16860
uniprot id: F2K4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

717774:MARME RS09115
gene id: 717774:MARME_RS09115
uniprot id: F2K1D2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS10985
gene id: 717774:MARME_RS10985
uniprot id: F2K4N8
names: Similarity
messages: Belongs to the YciI family.

717774:MARME RS05315
gene id: 717774:MARME_RS05315
uniprot id: F2JTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS06240
gene id: 717774:MARME_RS06240
uniprot id: F2JUU5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

717774:MARME RS05815
gene id: 717774:MARME_RS05815
uniprot id: F2JU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

717774:MARME RS14770
gene id: 717774:MARME_RS14770
uniprot id: F2K0S1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

717774:MARME RS09910
gene id: 717774:MARME_RS09910
uniprot id: F2K2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

717774:MARME RS16090
gene id: 717774:MARME_RS16090
uniprot id: F2K324
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

717774:MARME RS10060
gene id: 717774:MARME_RS10060
uniprot id: F2K3A7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

717774:MARME RS07655
gene id: 717774:MARME_RS07655
uniprot id: F2JY53
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS02745
gene id: 717774:MARME_RS02745
uniprot id: F2K0C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

717774:MARME RS14950
gene id: 717774:MARME_RS14950
uniprot id: F2K1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

717774:MARME RS17085
gene id: 717774:MARME_RS17085
uniprot id: F2K4X0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS13035
gene id: 717774:MARME_RS13035
uniprot id: F2JWQ9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

717774:MARME RS15230
gene id: 717774:MARME_RS15230
uniprot id: F2K1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS13225
gene id: 717774:MARME_RS13225
uniprot id: F2JXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS19810
gene id: 717774:MARME_RS19810
uniprot id: F2JYM1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS07410
gene id: 717774:MARME_RS07410
uniprot id: F2JY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

717774:MARME RS17405
gene id: 717774:MARME_RS17405
uniprot id: F2JTQ7
names: Similarity
messages: Belongs to the GppA/Ppx family.

717774:MARME RS08895
gene id: 717774:MARME_RS08895
uniprot id: F2K188
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

717774:MARME RS13060
gene id: 717774:MARME_RS13060
uniprot id: F2JWR4
names: Similarity
messages: Belongs to the HisA/HisF family.

717774:MARME RS15895
gene id: 717774:MARME_RS15895
uniprot id: F2K2Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

717774:MARME RS06750
gene id: 717774:MARME_RS06750
uniprot id: F2JWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

717774:MARME RS02240
gene id: 717774:MARME_RS02240
uniprot id: F2JZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS15825
gene id: 717774:MARME_RS15825
uniprot id: F2K2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

717774:MARME RS01810
gene id: 717774:MARME_RS01810
uniprot id: F2JYN4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

717774:MARME RS06045
gene id: 717774:MARME_RS06045
uniprot id: F2JUQ5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

717774:MARME RS15030
gene id: 717774:MARME_RS15030
uniprot id: F2K1I1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

717774:MARME RS20020
gene id: 717774:MARME_RS20020
uniprot id: F2JZA9
names: Similarity
messages: Belongs to the PspA/IM30 family.

717774:MARME RS10855
gene id: 717774:MARME_RS10855
uniprot id: F2K4L2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS20375
gene id: 717774:MARME_RS20375
uniprot id: F2K047
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

717774:MARME RS10515
gene id: 717774:MARME_RS10515
uniprot id: F2K3Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

717774:MARME RS18400
gene id: 717774:MARME_RS18400
uniprot id: F2JVY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

717774:MARME RS06395
gene id: 717774:MARME_RS06395
uniprot id: F2JVJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS15910
gene id: 717774:MARME_RS15910
uniprot id: F2K2Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

717774:MARME RS02860
gene id: 717774:MARME_RS02860
uniprot id: F2K0F2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

717774:MARME RS07150
gene id: 717774:MARME_RS07150
uniprot id: F2JX84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS07330
gene id: 717774:MARME_RS07330
uniprot id: F2JXC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

717774:MARME RS03565
gene id: 717774:MARME_RS03565
uniprot id: F2K1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

717774:MARME RS10420
gene id: 717774:MARME_RS10420
uniprot id: F2K3X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

717774:MARME RS21190
gene id: 717774:MARME_RS21190
uniprot id: F2K1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

717774:MARME RS01995
gene id: 717774:MARME_RS01995
uniprot id: F2JYR9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS15000
gene id: 717774:MARME_RS15000
uniprot id: F2K1H5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

717774:MARME RS03205
gene id: 717774:MARME_RS03205
uniprot id: F2K173
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

717774:MARME RS11280
gene id: 717774:MARME_RS11280
uniprot id: F2JTH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

717774:MARME RS03040
gene id: 717774:MARME_RS03040
uniprot id: F2K145
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

717774:MARME RS08915
gene id: 717774:MARME_RS08915
uniprot id: F2K192
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

717774:MARME RS16340
gene id: 717774:MARME_RS16340
uniprot id: F2K3M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS06220
gene id: 717774:MARME_RS06220
uniprot id: F2JUU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717774:MARME RS15485
gene id: 717774:MARME_RS15485
uniprot id: F2K2B9
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

717774:MARME RS02805
gene id: 717774:MARME_RS02805
uniprot id: F2K0E1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

717774:MARME RS17275
gene id: 717774:MARME_RS17275
uniprot id: F2JTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

717774:MARME RS11000
gene id: 717774:MARME_RS11000
uniprot id: F2K4P1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

717774:MARME RS00115
gene id: 717774:MARME_RS00115
uniprot id: F2JUJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS04755
gene id: 717774:MARME_RS04755
uniprot id: F2K3W5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS14910
gene id: 717774:MARME_RS14910
uniprot id: F2K0V0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

717774:MARME RS10800
gene id: 717774:MARME_RS10800
uniprot id: F2K4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

717774:MARME RS11425
gene id: 717774:MARME_RS11425
uniprot id: F2JTK5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS03750
gene id: 717774:MARME_RS03750
uniprot id: F2K2I4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS06780
gene id: 717774:MARME_RS06780
uniprot id: F2JWE3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

717774:MARME RS14265
gene id: 717774:MARME_RS14265
uniprot id: F2JZV3
names: Similarity
messages: Belongs to the DEAD box helicase family.

717774:MARME RS16290
gene id: 717774:MARME_RS16290
uniprot id: F2K3L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

717774:MARME RS13560
gene id: 717774:MARME_RS13560
uniprot id: F2JY97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS15765
gene id: 717774:MARME_RS15765
uniprot id: F2K2W6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS06500
gene id: 717774:MARME_RS06500
uniprot id: F2JVL9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

717774:MARME RS05800
gene id: 717774:MARME_RS05800
uniprot id: F2JU02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS00015
gene id: 717774:MARME_RS00015
uniprot id: F2JUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

717774:MARME RS20575
gene id: 717774:MARME_RS20575
uniprot id: F2K081
names: Similarity
messages: Belongs to the cytochrome P450 family.

717774:MARME RS15040
gene id: 717774:MARME_RS15040
uniprot id: F2K1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

717774:MARME RS10075
gene id: 717774:MARME_RS10075
uniprot id: F2K3B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

717774:MARME RS19275
gene id: 717774:MARME_RS19275
uniprot id: F2JXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS16120
gene id: 717774:MARME_RS16120
uniprot id: F2K3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

717774:MARME RS17790
gene id: 717774:MARME_RS17790
uniprot id: F2JUD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS04930
gene id: 717774:MARME_RS04930
uniprot id: F2K4F0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

717774:MARME RS18250
gene id: 717774:MARME_RS18250
uniprot id: F2JV84
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

717774:MARME RS05460
gene id: 717774:MARME_RS05460
uniprot id: F2JTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS15880
gene id: 717774:MARME_RS15880
uniprot id: F2K2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

717774:MARME RS17030
gene id: 717774:MARME_RS17030
uniprot id: F2K4V9
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

717774:MARME RS00750
gene id: 717774:MARME_RS00750
uniprot id: F2JW66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

717774:MARME RS15130
gene id: 717774:MARME_RS15130
uniprot id: F2K1K1
names: Similarity
messages: Belongs to the peptidase M18 family.

717774:MARME RS07475
gene id: 717774:MARME_RS07475
uniprot id: F2JY19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

717774:MARME RS03460
gene id: 717774:MARME_RS03460
uniprot id: F2K1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

717774:MARME RS04935
gene id: 717774:MARME_RS04935
uniprot id: F2K4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

717774:MARME RS15015
gene id: 717774:MARME_RS15015
uniprot id: F2K1H8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

717774:MARME RS15305
gene id: 717774:MARME_RS15305
uniprot id: F2K1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

717774:MARME RS03570
gene id: 717774:MARME_RS03570
uniprot id: F2K1Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

717774:MARME RS04115
gene id: 717774:MARME_RS04115
uniprot id: F2K342
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12805
gene id: 717774:MARME_RS12805
uniprot id: F2JWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

717774:MARME RS10895
gene id: 717774:MARME_RS10895
uniprot id: F2K4M0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS01345
gene id: 717774:MARME_RS01345
uniprot id: F2JX51
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS04430
gene id: 717774:MARME_RS04430
uniprot id: F2K397
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

717774:MARME RS17455
gene id: 717774:MARME_RS17455
uniprot id: F2JTR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

717774:MARME RS14885
gene id: 717774:MARME_RS14885
uniprot id: F2K0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

717774:MARME RS16795
gene id: 717774:MARME_RS16795
uniprot id: F2K4B4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

717774:MARME RS06715
gene id: 717774:MARME_RS06715
uniprot id: F2JWD0
names: Similarity
messages: Belongs to the universal stress protein A family.

717774:MARME RS04880
gene id: 717774:MARME_RS04880
uniprot id: F2K4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS08945
gene id: 717774:MARME_RS08945
uniprot id: F2K198
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS16475
gene id: 717774:MARME_RS16475
uniprot id: F2K3Q1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS02620
gene id: 717774:MARME_RS02620
uniprot id: F2K0A3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

717774:MARME RS14135
gene id: 717774:MARME_RS14135
uniprot id: F2JZ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

717774:MARME RS10045
gene id: 717774:MARME_RS10045
uniprot id: F2K3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

717774:MARME RS06820
gene id: 717774:MARME_RS06820
uniprot id: F2JWF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16590
gene id: 717774:MARME_RS16590
uniprot id: F2K472
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

717774:MARME RS04355
gene id: 717774:MARME_RS04355
uniprot id: F2K383
names: Subunit
messages: Homodimer.

717774:MARME RS19000
gene id: 717774:MARME_RS19000
uniprot id: F2JWX1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

717774:MARME RS14720
gene id: 717774:MARME_RS14720
uniprot id: F2K0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS10340
gene id: 717774:MARME_RS10340
uniprot id: F2K3G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

717774:MARME RS11270
gene id: 717774:MARME_RS11270
uniprot id: F2JTH4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

717774:MARME RS21230
gene id: 717774:MARME_RS21230
uniprot id: F2K1U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

717774:MARME RS01600
gene id: 717774:MARME_RS01600
uniprot id: F2JXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS16035
gene id: 717774:MARME_RS16035
uniprot id: F2K313
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

717774:MARME RS20360
gene id: 717774:MARME_RS20360
uniprot id: F2K044
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

717774:MARME RS20065
gene id: 717774:MARME_RS20065
uniprot id: F2JZB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS01335
gene id: 717774:MARME_RS01335
uniprot id: F2JX49
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

717774:MARME RS07505
gene id: 717774:MARME_RS07505
uniprot id: F2JY25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS05990
gene id: 717774:MARME_RS05990
uniprot id: F2JUP4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

717774:MARME RS17665
gene id: 717774:MARME_RS17665
uniprot id: F2JUB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

717774:MARME RS05680
gene id: 717774:MARME_RS05680
uniprot id: F2JTX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

717774:MARME RS15595
gene id: 717774:MARME_RS15595
uniprot id: F2K2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

717774:MARME RS20840
gene id: 717774:MARME_RS20840
uniprot id: F2K0Z7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

717774:MARME RS02500
gene id: 717774:MARME_RS02500
uniprot id: F2JZL1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

717774:MARME RS17615
gene id: 717774:MARME_RS17615
uniprot id: F2JTU9
names: Similarity
messages: Belongs to the glutamate synthase family.

717774:MARME RS01220
gene id: 717774:MARME_RS01220
uniprot id: F2JX26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

717774:MARME RS16200
gene id: 717774:MARME_RS16200
uniprot id: F2K3J5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

717774:MARME RS03780
gene id: 717774:MARME_RS03780
uniprot id: F2K2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

717774:MARME RS19155
gene id: 717774:MARME_RS19155
uniprot id: F2JXM1
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

717774:MARME RS05105
gene id: 717774:MARME_RS05105
uniprot id: F2K4I3
names: Similarity
messages: Belongs to the PhoH family.

717774:MARME RS19015
gene id: 717774:MARME_RS19015
uniprot id: F2JWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS17255
gene id: 717774:MARME_RS17255
uniprot id: F2JTM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

717774:MARME RS12200
gene id: 717774:MARME_RS12200
uniprot id: F2JV07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

717774:MARME RS01705
gene id: 717774:MARME_RS01705
uniprot id: F2JXZ0
names: Similarity
messages: Belongs to the Gfa family.

717774:MARME RS16940
gene id: 717774:MARME_RS16940
uniprot id: F2K4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

717774:MARME RS00480
gene id: 717774:MARME_RS00480
uniprot id: F2JVE4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS13075
gene id: 717774:MARME_RS13075
uniprot id: F2JWR7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

717774:MARME RS00945
gene id: 717774:MARME_RS00945
uniprot id: F2JWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

717774:MARME RS18350
gene id: 717774:MARME_RS18350
uniprot id: F2JVA3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

717774:MARME RS11630
gene id: 717774:MARME_RS11630
uniprot id: F2JU43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

717774:MARME RS04870
gene id: 717774:MARME_RS04870
uniprot id: F2K4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS02615
gene id: 717774:MARME_RS02615
uniprot id: F2K0A2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS14425
gene id: 717774:MARME_RS14425
uniprot id: F2JZY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

717774:MARME RS13350
gene id: 717774:MARME_RS13350
uniprot id: F2JXI5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS12635
gene id: 717774:MARME_RS12635
uniprot id: F2JVV9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

717774:MARME RS12705
gene id: 717774:MARME_RS12705
uniprot id: F2JVX3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS20805
gene id: 717774:MARME_RS20805
uniprot id: F2K0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

717774:MARME RS14895
gene id: 717774:MARME_RS14895
uniprot id: F2K0U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

717774:MARME RS08775
gene id: 717774:MARME_RS08775
uniprot id: F2K0K9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS11970
gene id: 717774:MARME_RS11970
uniprot id: F2JUW6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

717774:MARME RS16485
gene id: 717774:MARME_RS16485
uniprot id: F2K451
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20190
gene id: 717774:MARME_RS20190
uniprot id: F2JZD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS17940
gene id: 717774:MARME_RS17940
uniprot id: F2JUG6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

717774:MARME RS06465
gene id: 717774:MARME_RS06465
uniprot id: F2JVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

717774:MARME RS01420
gene id: 717774:MARME_RS01420
uniprot id: F2JX65
names: Similarity
messages: Belongs to the peptidase M16 family.

717774:MARME RS00010
gene id: 717774:MARME_RS00010
uniprot id: F2JUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

717774:MARME RS01085
gene id: 717774:MARME_RS01085
uniprot id: F2JX03
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

717774:MARME RS15145
gene id: 717774:MARME_RS15145
uniprot id: F2K1K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

717774:MARME RS06825
gene id: 717774:MARME_RS06825
uniprot id: F2JWF2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

717774:MARME RS16360
gene id: 717774:MARME_RS16360
uniprot id: F2K3M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

717774:MARME RS07555
gene id: 717774:MARME_RS07555
uniprot id: F2JY35
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

717774:MARME RS11355
gene id: 717774:MARME_RS11355
uniprot id: F2JTJ1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

717774:MARME RS12275
gene id: 717774:MARME_RS12275
uniprot id: F2JV22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

717774:MARME RS12840
gene id: 717774:MARME_RS12840
uniprot id: F2JWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

717774:MARME RS09505
gene id: 717774:MARME_RS09505
uniprot id: F2K264
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

717774:MARME RS19005
gene id: 717774:MARME_RS19005
uniprot id: F2JWX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

717774:MARME RS07430
gene id: 717774:MARME_RS07430
uniprot id: F2JY10
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

717774:MARME RS00200
gene id: 717774:MARME_RS00200
uniprot id: F2JUL2
names: Similarity
messages: Belongs to the proline racemase family.

717774:MARME RS14485
gene id: 717774:MARME_RS14485
uniprot id: F2JZZ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS17445
gene id: 717774:MARME_RS17445
uniprot id: F2JTR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

717774:MARME RS12850
gene id: 717774:MARME_RS12850
uniprot id: F2JWM4
names: Similarity
messages: Belongs to the MotB family.

717774:MARME RS14975
gene id: 717774:MARME_RS14975
uniprot id: F2K1H0
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS02915
gene id: 717774:MARME_RS02915
uniprot id: F2K128
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717774:MARME RS17830
gene id: 717774:MARME_RS17830
uniprot id: F2JUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

717774:MARME RS08595
gene id: 717774:MARME_RS08595
uniprot id: F2K0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

717774:MARME RS07935
gene id: 717774:MARME_RS07935
uniprot id: F2JYW3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS06540
gene id: 717774:MARME_RS06540
uniprot id: F2JVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS05940
gene id: 717774:MARME_RS05940
uniprot id: F2JUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

717774:MARME RS14315
gene id: 717774:MARME_RS14315
uniprot id: F2JZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

717774:MARME RS13095
gene id: 717774:MARME_RS13095
uniprot id: F2JWS1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

717774:MARME RS06635
gene id: 717774:MARME_RS06635
uniprot id: F2JVP4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

717774:MARME RS07660
gene id: 717774:MARME_RS07660
uniprot id: F2JY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

717774:MARME RS01835
gene id: 717774:MARME_RS01835
uniprot id: F2JYN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS09060
gene id: 717774:MARME_RS09060
uniprot id: F2K1C1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

717774:MARME RS02505
gene id: 717774:MARME_RS02505
uniprot id: F2JZL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

717774:MARME RS01440
gene id: 717774:MARME_RS01440
uniprot id: F2JXT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

717774:MARME RS17995
gene id: 717774:MARME_RS17995
uniprot id: F2JV38
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

717774:MARME RS00615
gene id: 717774:MARME_RS00615
uniprot id: F2JVG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

717774:MARME RS12630
gene id: 717774:MARME_RS12630
uniprot id: F2JVV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS11655
gene id: 717774:MARME_RS11655
uniprot id: F2JU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

717774:MARME RS04665
gene id: 717774:MARME_RS04665
uniprot id: F2K3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS07800
gene id: 717774:MARME_RS07800
uniprot id: F2JYV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

717774:MARME RS09225
gene id: 717774:MARME_RS09225
uniprot id: F2K1F4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

717774:MARME RS14620
gene id: 717774:MARME_RS14620
uniprot id: F2K0P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

717774:MARME RS00900
gene id: 717774:MARME_RS00900
uniprot id: F2JW96
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717774:MARME RS14780
gene id: 717774:MARME_RS14780
uniprot id: F2K0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS12520
gene id: 717774:MARME_RS12520
uniprot id: F2JVT6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Catalyzes the reversible isomerization of D-mannose to D-fructose. Can also isomerize D-lyxose, with lower efficiency. In longer reaction with a higher concentration of enzyme, it can isomerize 4-OH D-mannose derivatives (D-talose and 4-O-monosaccharyl-D-mannose). Cannot use D-glucose.
messages: Monomer.
messages: The alpha7-alpha8 and alpha11-alpha12 loops of the catalytic domain may participate in the formation of an open substrate-binding site to provide sufficient space to bind 4-OH D-mannose derivatives.

717774:MARME RS04295
gene id: 717774:MARME_RS04295
uniprot id: F2K372
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS06740
gene id: 717774:MARME_RS06740
uniprot id: F2JWD5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

717774:MARME RS08965
gene id: 717774:MARME_RS08965
uniprot id: F2K1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

717774:MARME RS04885
gene id: 717774:MARME_RS04885
uniprot id: F2K4E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS00745
gene id: 717774:MARME_RS00745
uniprot id: F2JW65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

717774:MARME RS11015
gene id: 717774:MARME_RS11015
uniprot id: F2K4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS01180
gene id: 717774:MARME_RS01180
uniprot id: F2JX18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

717774:MARME RS21980
gene id: 717774:MARME_RS21980
uniprot id: F2K1U3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

717774:MARME RS05125
gene id: 717774:MARME_RS05125
uniprot id: F2K4I7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

717774:MARME RS12780
gene id: 717774:MARME_RS12780
uniprot id: F2JWL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

717774:MARME RS16895
gene id: 717774:MARME_RS16895
uniprot id: F2K4T2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

717774:MARME RS07615
gene id: 717774:MARME_RS07615
uniprot id: F2JY46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

717774:MARME RS09485
gene id: 717774:MARME_RS09485
uniprot id: F2K260
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS10735
gene id: 717774:MARME_RS10735
uniprot id: F2K438
names: Similarity
messages: Belongs to the SUI1 family.

717774:MARME RS01950
gene id: 717774:MARME_RS01950
uniprot id: F2JYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS18700
gene id: 717774:MARME_RS18700
uniprot id: F2JW42
names: Similarity
messages: Belongs to the bacterial secretin family.

717774:MARME RS02700
gene id: 717774:MARME_RS02700
uniprot id: F2K0C0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20035
gene id: 717774:MARME_RS20035
uniprot id: F2JZB2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

717774:MARME RS10250
gene id: 717774:MARME_RS10250
uniprot id: F2K3E5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

717774:MARME RS14590
gene id: 717774:MARME_RS14590
uniprot id: F2K0N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS06215
gene id: 717774:MARME_RS06215
uniprot id: F2JUU0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

717774:MARME RS18230
gene id: 717774:MARME_RS18230
uniprot id: F2JV80
names: Similarity
messages: Belongs to the ketopantoate reductase family.

717774:MARME RS01965
gene id: 717774:MARME_RS01965
uniprot id: F2JYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS11690
gene id: 717774:MARME_RS11690
uniprot id: F2JU55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

717774:MARME RS00070
gene id: 717774:MARME_RS00070
uniprot id: F2JUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

717774:MARME RS10025
gene id: 717774:MARME_RS10025
uniprot id: F2K3A0
names: Similarity
messages: Belongs to the UPF0434 family.

717774:MARME RS04810
gene id: 717774:MARME_RS04810
uniprot id: F2K3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS12030
gene id: 717774:MARME_RS12030
uniprot id: F2JUX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS02355
gene id: 717774:MARME_RS02355
uniprot id: F2JZI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS06080
gene id: 717774:MARME_RS06080
uniprot id: F2JUR2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

717774:MARME RS14905
gene id: 717774:MARME_RS14905
uniprot id: F2K0U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

717774:MARME RS05955
gene id: 717774:MARME_RS05955
uniprot id: F2JUN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

717774:MARME RS20300
gene id: 717774:MARME_RS20300
uniprot id: F2K032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS10040
gene id: 717774:MARME_RS10040
uniprot id: F2K3A3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

717774:MARME RS01185
gene id: 717774:MARME_RS01185
uniprot id: F2JX19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

717774:MARME RS19625
gene id: 717774:MARME_RS19625
uniprot id: F2JYI5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS00820
gene id: 717774:MARME_RS00820
uniprot id: F2JW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS09585
gene id: 717774:MARME_RS09585
uniprot id: F2K278
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

717774:MARME RS13115
gene id: 717774:MARME_RS13115
uniprot id: F2JXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS01205
gene id: 717774:MARME_RS01205
uniprot id: F2JX23
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

717774:MARME RS20195
gene id: 717774:MARME_RS20195
uniprot id: F2JZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

717774:MARME RS09905
gene id: 717774:MARME_RS09905
uniprot id: F2K2T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

717774:MARME RS09870
gene id: 717774:MARME_RS09870
uniprot id: F2K2S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

717774:MARME RS19195
gene id: 717774:MARME_RS19195
uniprot id: F2JXN0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS02765
gene id: 717774:MARME_RS02765
uniprot id: F2K0D3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717774:MARME RS05600
gene id: 717774:MARME_RS05600
uniprot id: F2JTW2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS16900
gene id: 717774:MARME_RS16900
uniprot id: F2K4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

717774:MARME RS07180
gene id: 717774:MARME_RS07180
uniprot id: F2JX90
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

717774:MARME RS03515
gene id: 717774:MARME_RS03515
uniprot id: F2K1Y8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

717774:MARME RS17045
gene id: 717774:MARME_RS17045
uniprot id: F2K4W2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS06855
gene id: 717774:MARME_RS06855
uniprot id: F2JWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

717774:MARME RS01500
gene id: 717774:MARME_RS01500
uniprot id: F2JXV1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

717774:MARME RS06745
gene id: 717774:MARME_RS06745
uniprot id: F2JWD6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

717774:MARME RS12385
gene id: 717774:MARME_RS12385
uniprot id: F2JVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

717774:MARME RS00775
gene id: 717774:MARME_RS00775
uniprot id: F2JW71
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

717774:MARME RS14220
gene id: 717774:MARME_RS14220
uniprot id: F2JZU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS07390
gene id: 717774:MARME_RS07390
uniprot id: F2JXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

717774:MARME RS11315
gene id: 717774:MARME_RS11315
uniprot id: F2JTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

717774:MARME RS14090
gene id: 717774:MARME_RS14090
uniprot id: F2JZ58
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS15790
gene id: 717774:MARME_RS15790
uniprot id: F2K2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

717774:MARME RS06690
gene id: 717774:MARME_RS06690
uniprot id: F2JWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

717774:MARME RS02310
gene id: 717774:MARME_RS02310
uniprot id: F2JZH4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

717774:MARME RS10265
gene id: 717774:MARME_RS10265
uniprot id: F2K3E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

717774:MARME RS06455
gene id: 717774:MARME_RS06455
uniprot id: F2JVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS07560
gene id: 717774:MARME_RS07560
uniprot id: F2JY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

717774:MARME RS10415
gene id: 717774:MARME_RS10415
uniprot id: F2K3X8
names: Similarity
messages: Belongs to the TrpF family.

717774:MARME RS16300
gene id: 717774:MARME_RS16300
uniprot id: F2K3L6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

717774:MARME RS14170
gene id: 717774:MARME_RS14170
uniprot id: F2JZ68
names: Similarity
messages: Belongs to the DsrF/TusC family.

717774:MARME RS10210
gene id: 717774:MARME_RS10210
uniprot id: F2K3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

717774:MARME RS11790
gene id: 717774:MARME_RS11790
uniprot id: F2JU75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

717774:MARME RS13030
gene id: 717774:MARME_RS13030
uniprot id: F2JWQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

717774:MARME RS14295
gene id: 717774:MARME_RS14295
uniprot id: F2JZV9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

717774:MARME RS04270
gene id: 717774:MARME_RS04270
uniprot id: F2K367
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

717774:MARME RS01445
gene id: 717774:MARME_RS01445
uniprot id: F2JXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

717774:MARME RS15440
gene id: 717774:MARME_RS15440
uniprot id: F2K2B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS07355
gene id: 717774:MARME_RS07355
uniprot id: F2JXC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS20270
gene id: 717774:MARME_RS20270
uniprot id: F2K026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

717774:MARME RS01325
gene id: 717774:MARME_RS01325
uniprot id: F2JX47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

717774:MARME RS19915
gene id: 717774:MARME_RS19915
uniprot id: F2JZ87
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

717774:MARME RS03590
gene id: 717774:MARME_RS03590
uniprot id: F2K203
names: Similarity
messages: Belongs to the UPF0047 family.

717774:MARME RS17160
gene id: 717774:MARME_RS17160
uniprot id: F2K4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

717774:MARME RS01395
gene id: 717774:MARME_RS01395
uniprot id: F2JX60
names: Similarity
messages: Belongs to the CDPS family.

717774:MARME RS05855
gene id: 717774:MARME_RS05855
uniprot id: F2JU13
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS05040
gene id: 717774:MARME_RS05040
uniprot id: F2K4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

717774:MARME RS13100
gene id: 717774:MARME_RS13100
uniprot id: F2JXD6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

717774:MARME RS01240
gene id: 717774:MARME_RS01240
uniprot id: F2JX30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS03210
gene id: 717774:MARME_RS03210
uniprot id: F2K174
names: Similarity
messages: Belongs to the phosphohexose mutase family.

717774:MARME RS07385
gene id: 717774:MARME_RS07385
uniprot id: F2JXD1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

717774:MARME RS02815
gene id: 717774:MARME_RS02815
uniprot id: F2K0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

717774:MARME RS06190
gene id: 717774:MARME_RS06190
uniprot id: F2JUT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS17480
gene id: 717774:MARME_RS17480
uniprot id: F2JTS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

717774:MARME RS03020
gene id: 717774:MARME_RS03020
uniprot id: F2K141
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

717774:MARME RS17340
gene id: 717774:MARME_RS17340
uniprot id: F2JTP4
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

717774:MARME RS16800
gene id: 717774:MARME_RS16800
uniprot id: F2K4B5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

717774:MARME RS02570
gene id: 717774:MARME_RS02570
uniprot id: F2K093
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

717774:MARME RS00955
gene id: 717774:MARME_RS00955
uniprot id: F2JWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

717774:MARME RS08490
gene id: 717774:MARME_RS08490
uniprot id: F2JZT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS05515
gene id: 717774:MARME_RS05515
uniprot id: F2JTE7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS00970
gene id: 717774:MARME_RS00970
uniprot id: F2JWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

717774:MARME RS05960
gene id: 717774:MARME_RS05960
uniprot id: F2JUN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

717774:MARME RS20645
gene id: 717774:MARME_RS20645
uniprot id: F2K0W0
names: Similarity
messages: Belongs to the peptidase A24 family.

717774:MARME RS07275
gene id: 717774:MARME_RS07275
uniprot id: F2JXA9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

717774:MARME RS07315
gene id: 717774:MARME_RS07315
uniprot id: F2JXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

717774:MARME RS05945
gene id: 717774:MARME_RS05945
uniprot id: F2JUN5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

717774:MARME RS14600
gene id: 717774:MARME_RS14600
uniprot id: F2K0P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

717774:MARME RS12810
gene id: 717774:MARME_RS12810
uniprot id: F2JWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

717774:MARME RS18915
gene id: 717774:MARME_RS18915
uniprot id: F2JWV4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS11235
gene id: 717774:MARME_RS11235
uniprot id: F2JTG7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

717774:MARME RS03500
gene id: 717774:MARME_RS03500
uniprot id: F2K1Y5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS10920
gene id: 717774:MARME_RS10920
uniprot id: F2K4M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

717774:MARME RS21215
gene id: 717774:MARME_RS21215
uniprot id: F2K1T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

717774:MARME RS04515
gene id: 717774:MARME_RS04515
uniprot id: F2K3R8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

717774:MARME RS03335
gene id: 717774:MARME_RS03335
uniprot id: F2K1V4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

717774:MARME RS00385
gene id: 717774:MARME_RS00385
uniprot id: F2JVC4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS06710
gene id: 717774:MARME_RS06710
uniprot id: F2JWC9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

717774:MARME RS02575
gene id: 717774:MARME_RS02575
uniprot id: F2K094
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

717774:MARME RS16705
gene id: 717774:MARME_RS16705
uniprot id: F2K495
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS06010
gene id: 717774:MARME_RS06010
uniprot id: F2JUP8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

717774:MARME RS03270
gene id: 717774:MARME_RS03270
uniprot id: F2K186
names: Similarity
messages: Belongs to the MQO family.

717774:MARME RS17265
gene id: 717774:MARME_RS17265
uniprot id: F2JTM9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

717774:MARME RS02825
gene id: 717774:MARME_RS02825
uniprot id: F2K0E5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

717774:MARME RS08320
gene id: 717774:MARME_RS08320
uniprot id: F2JZQ1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS00810
gene id: 717774:MARME_RS00810
uniprot id: F2JW78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS11670
gene id: 717774:MARME_RS11670
uniprot id: F2JU51
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

717774:MARME RS10945
gene id: 717774:MARME_RS10945
uniprot id: F2K4N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS15690
gene id: 717774:MARME_RS15690
uniprot id: F2K2G0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

717774:MARME RS10455
gene id: 717774:MARME_RS10455
uniprot id: F2K3Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

717774:MARME RS10010
gene id: 717774:MARME_RS10010
uniprot id: F2K2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

717774:MARME RS14820
gene id: 717774:MARME_RS14820
uniprot id: F2K0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

717774:MARME RS02485
gene id: 717774:MARME_RS02485
uniprot id: F2JZK8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

717774:MARME RS10500
gene id: 717774:MARME_RS10500
uniprot id: F2K3Z5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

717774:MARME RS08975
gene id: 717774:MARME_RS08975
uniprot id: F2K1A4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS06185
gene id: 717774:MARME_RS06185
uniprot id: F2JUT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

717774:MARME RS15885
gene id: 717774:MARME_RS15885
uniprot id: F2K2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

717774:MARME RS14205
gene id: 717774:MARME_RS14205
uniprot id: F2JZU1
names: Similarity
messages: Belongs to the isochorismate synthase family.

717774:MARME RS18150
gene id: 717774:MARME_RS18150
uniprot id: F2JV64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

717774:MARME RS05625
gene id: 717774:MARME_RS05625
uniprot id: F2JTW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

717774:MARME RS18260
gene id: 717774:MARME_RS18260
uniprot id: F2JV86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS15395
gene id: 717774:MARME_RS15395
uniprot id: F2K2A3
names: Similarity
messages: Belongs to the UPF0229 family.

717774:MARME RS20555
gene id: 717774:MARME_RS20555
uniprot id: F2K077
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

717774:MARME RS13210
gene id: 717774:MARME_RS13210
uniprot id: F2JXF7
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS04815
gene id: 717774:MARME_RS04815
uniprot id: F2K4C7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS17715
gene id: 717774:MARME_RS17715
uniprot id: F2JUB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS12300
gene id: 717774:MARME_RS12300
uniprot id: F2JV27
names: Similarity
messages: Belongs to the glutamine synthetase family.

717774:MARME RS16920
gene id: 717774:MARME_RS16920
uniprot id: F2K4T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

717774:MARME RS11025
gene id: 717774:MARME_RS11025
uniprot id: F2K4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS18930
gene id: 717774:MARME_RS18930
uniprot id: F2JWV7
names: Similarity
messages: Belongs to the nitroreductase family.

717774:MARME RS03600
gene id: 717774:MARME_RS03600
uniprot id: F2K205
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

717774:MARME RS04035
gene id: 717774:MARME_RS04035
uniprot id: F2K2N4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS14080
gene id: 717774:MARME_RS14080
uniprot id: F2JZ56
names: Similarity
messages: Belongs to the Gfa family.

717774:MARME RS01285
gene id: 717774:MARME_RS01285
uniprot id: F2JX39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

717774:MARME RS00040
gene id: 717774:MARME_RS00040
uniprot id: F2JUI0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS08120
gene id: 717774:MARME_RS08120
uniprot id: F2JZ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

717774:MARME RS17585
gene id: 717774:MARME_RS17585
uniprot id: F2JTU3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

717774:MARME RS18040
gene id: 717774:MARME_RS18040
uniprot id: F2JV47
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

717774:MARME RS09570
gene id: 717774:MARME_RS09570
uniprot id: F2K275
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

717774:MARME RS06015
gene id: 717774:MARME_RS06015
uniprot id: F2JUP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

717774:MARME RS00670
gene id: 717774:MARME_RS00670
uniprot id: F2JVI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS17380
gene id: 717774:MARME_RS17380
uniprot id: F2JTQ2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

717774:MARME RS16235
gene id: 717774:MARME_RS16235
uniprot id: F2K3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

717774:MARME RS06460
gene id: 717774:MARME_RS06460
uniprot id: F2JVL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS05995
gene id: 717774:MARME_RS05995
uniprot id: F2JUP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS11300
gene id: 717774:MARME_RS11300
uniprot id: F2JTI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

717774:MARME RS10085
gene id: 717774:MARME_RS10085
uniprot id: F2K3B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

717774:MARME RS02875
gene id: 717774:MARME_RS02875
uniprot id: F2K0F5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

717774:MARME RS13890
gene id: 717774:MARME_RS13890
uniprot id: F2JZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

717774:MARME RS19280
gene id: 717774:MARME_RS19280
uniprot id: F2JXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS03760
gene id: 717774:MARME_RS03760
uniprot id: F2K2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

717774:MARME RS13895
gene id: 717774:MARME_RS13895
uniprot id: F2JZ19
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

717774:MARME RS12570
gene id: 717774:MARME_RS12570
uniprot id: F2JVU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717774:MARME RS10170
gene id: 717774:MARME_RS10170
uniprot id: F2K3C9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS13025
gene id: 717774:MARME_RS13025
uniprot id: F2JWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

717774:MARME RS09985
gene id: 717774:MARME_RS09985
uniprot id: F2K2V0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

717774:MARME RS10015
gene id: 717774:MARME_RS10015
uniprot id: F2K398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

717774:MARME RS01465
gene id: 717774:MARME_RS01465
uniprot id: F2JXU4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

717774:MARME RS11090
gene id: 717774:MARME_RS11090
uniprot id: F2K4Q9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

717774:MARME RS06130
gene id: 717774:MARME_RS06130
uniprot id: F2JUS2
names: Similarity
messages: Belongs to the HesB/IscA family.

717774:MARME RS18100
gene id: 717774:MARME_RS18100
uniprot id: F2JV54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

717774:MARME RS16970
gene id: 717774:MARME_RS16970
uniprot id: F2K4U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

717774:MARME RS12800
gene id: 717774:MARME_RS12800
uniprot id: F2JWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

717774:MARME RS02185
gene id: 717774:MARME_RS02185
uniprot id: F2JZE9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

717774:MARME RS05745
gene id: 717774:MARME_RS05745
uniprot id: F2JTZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

717774:MARME RS14390
gene id: 717774:MARME_RS14390
uniprot id: F2JZX8
names: Similarity
messages: Belongs to the DEAD box helicase family.

717774:MARME RS15635
gene id: 717774:MARME_RS15635
uniprot id: F2K2E9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

717774:MARME RS03080
gene id: 717774:MARME_RS03080
uniprot id: F2K153
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

717774:MARME RS20110
gene id: 717774:MARME_RS20110
uniprot id: F2JZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS11985
gene id: 717774:MARME_RS11985
uniprot id: F2JUW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS12990
gene id: 717774:MARME_RS12990
uniprot id: F2JWQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

717774:MARME RS08090
gene id: 717774:MARME_RS08090
uniprot id: F2JYZ4
names: Similarity
messages: Belongs to the RuBisCO large chain family.

717774:MARME RS13780
gene id: 717774:MARME_RS13780
uniprot id: F2JYE1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

717774:MARME RS16700
gene id: 717774:MARME_RS16700
uniprot id: F2K494
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS11470
gene id: 717774:MARME_RS11470
uniprot id: F2JTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS02760
gene id: 717774:MARME_RS02760
uniprot id: F2K0D2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS13240
gene id: 717774:MARME_RS13240
uniprot id: F2JXG3
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS08885
gene id: 717774:MARME_RS08885
uniprot id: F2K0N3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

717774:MARME RS09500
gene id: 717774:MARME_RS09500
uniprot id: F2K263
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

717774:MARME RS08550
gene id: 717774:MARME_RS08550
uniprot id: F2K0G5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

717774:MARME RS06815
gene id: 717774:MARME_RS06815
uniprot id: F2JWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

717774:MARME RS05905
gene id: 717774:MARME_RS05905
uniprot id: F2JU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS03480
gene id: 717774:MARME_RS03480
uniprot id: F2K1Y1
names: Similarity
messages: Belongs to the threonine synthase family.

717774:MARME RS17660
gene id: 717774:MARME_RS17660
uniprot id: F2JUB0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS04590
gene id: 717774:MARME_RS04590
uniprot id: F2K3T4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12770
gene id: 717774:MARME_RS12770
uniprot id: F2JWK8
names: Similarity
messages: Belongs to the ArsC family.

717774:MARME RS17960
gene id: 717774:MARME_RS17960
uniprot id: F2JUH0
names: Similarity
messages: Belongs to the histone deacetylase family.

717774:MARME RS20345
gene id: 717774:MARME_RS20345
uniprot id: F2K041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS15740
gene id: 717774:MARME_RS15740
uniprot id: F2K2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS06005
gene id: 717774:MARME_RS06005
uniprot id: F2JUP7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

717774:MARME RS19740
gene id: 717774:MARME_RS19740
uniprot id: F2JYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS06175
gene id: 717774:MARME_RS06175
uniprot id: F2JUT1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

717774:MARME RS00525
gene id: 717774:MARME_RS00525
uniprot id: F2JVF3
names: Similarity
messages: Belongs to the YjdM family.

717774:MARME RS03605
gene id: 717774:MARME_RS03605
uniprot id: F2K206
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS21225
gene id: 717774:MARME_RS21225
uniprot id: F2K1U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

717774:MARME RS12100
gene id: 717774:MARME_RS12100
uniprot id: F2JUZ1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

717774:MARME RS05840
gene id: 717774:MARME_RS05840
uniprot id: F2JU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

717774:MARME RS05400
gene id: 717774:MARME_RS05400
uniprot id: F2JTC4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717774:MARME RS20910
gene id: 717774:MARME_RS20910
uniprot id: F2K111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

717774:MARME RS05090
gene id: 717774:MARME_RS05090
uniprot id: F2K4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

717774:MARME RS14535
gene id: 717774:MARME_RS14535
uniprot id: F2K008
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

717774:MARME RS15720
gene id: 717774:MARME_RS15720
uniprot id: F2K2V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

717774:MARME RS10965
gene id: 717774:MARME_RS10965
uniprot id: F2K4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

717774:MARME RS00720
gene id: 717774:MARME_RS00720
uniprot id: F2JW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS11965
gene id: 717774:MARME_RS11965
uniprot id: F2JUW5
names: Similarity
messages: Belongs to the YciI family.

717774:MARME RS06770
gene id: 717774:MARME_RS06770
uniprot id: F2JWE1
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS10885
gene id: 717774:MARME_RS10885
uniprot id: F2K4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS16230
gene id: 717774:MARME_RS16230
uniprot id: F2K3K1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

717774:MARME RS05845
gene id: 717774:MARME_RS05845
uniprot id: F2JU11
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

717774:MARME RS06300
gene id: 717774:MARME_RS06300
uniprot id: F2JUV7
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS17700
gene id: 717774:MARME_RS17700
uniprot id: F2JUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS15640
gene id: 717774:MARME_RS15640
uniprot id: F2K2F0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

717774:MARME RS04015
gene id: 717774:MARME_RS04015
uniprot id: F2K2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

717774:MARME RS01075
gene id: 717774:MARME_RS01075
uniprot id: F2JX01
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS06050
gene id: 717774:MARME_RS06050
uniprot id: F2JUQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

717774:MARME RS12565
gene id: 717774:MARME_RS12565
uniprot id: F2JVU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717774:MARME RS04795
gene id: 717774:MARME_RS04795
uniprot id: F2K3X3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS16880
gene id: 717774:MARME_RS16880
uniprot id: F2K4S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

717774:MARME RS14530
gene id: 717774:MARME_RS14530
uniprot id: F2K007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS20740
gene id: 717774:MARME_RS20740
uniprot id: F2K0X9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

717774:MARME RS06880
gene id: 717774:MARME_RS06880
uniprot id: F2JWG3
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

717774:MARME RS01235
gene id: 717774:MARME_RS01235
uniprot id: F2JX29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

717774:MARME RS20105
gene id: 717774:MARME_RS20105
uniprot id: F2JZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS17320
gene id: 717774:MARME_RS17320
uniprot id: F2JTP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS14250
gene id: 717774:MARME_RS14250
uniprot id: F2JZV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

717774:MARME RS18755
gene id: 717774:MARME_RS18755
uniprot id: F2JWS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

717774:MARME RS04685
gene id: 717774:MARME_RS04685
uniprot id: F2K3V1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

717774:MARME RS12670
gene id: 717774:MARME_RS12670
uniprot id: F2JVW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

717774:MARME RS02445
gene id: 717774:MARME_RS02445
uniprot id: F2JZK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

717774:MARME RS19590
gene id: 717774:MARME_RS19590
uniprot id: F2JYH8
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS03470
gene id: 717774:MARME_RS03470
uniprot id: F2K1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

717774:MARME RS12365
gene id: 717774:MARME_RS12365
uniprot id: F2JVR0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

717774:MARME RS15155
gene id: 717774:MARME_RS15155
uniprot id: F2K1K6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS13385
gene id: 717774:MARME_RS13385
uniprot id: F2JXJ2
names: Cofactor
names: Disruption Phenotype
names: Function
names: Induction
names: Miscellaneous
names: Subcellular Location Annotation
messages: Binds 1 FAD per subunit.
messages: Cells lacking this gene do not show any lysine-epsilon oxidase activity.
messages: Cytoplasm
messages: Forms part of an operon with lodA.
messages: Is required for lysine-epsilon oxidase (LOD) activity in M.mediterranea. May be involved in the generation of the quinonic cofactor of LodA, leading to the active form of LodA containing a tyrosine-derived quinone cofactor.
messages: The intracellular stability of LodB is dependent on the presence of LodA protein.

717774:MARME RS08985
gene id: 717774:MARME_RS08985
uniprot id: F2K1A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

717774:MARME RS16345
gene id: 717774:MARME_RS16345
uniprot id: F2K3M5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

717774:MARME RS19615
gene id: 717774:MARME_RS19615
uniprot id: F2JYI3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS01460
gene id: 717774:MARME_RS01460
uniprot id: F2JXU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

717774:MARME RS15590
gene id: 717774:MARME_RS15590
uniprot id: F2K2E0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12205
gene id: 717774:MARME_RS12205
uniprot id: F2JV08
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

717774:MARME RS14695
gene id: 717774:MARME_RS14695
uniprot id: F2K0R0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

717774:MARME RS08505
gene id: 717774:MARME_RS08505
uniprot id: F2JZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS10430
gene id: 717774:MARME_RS10430
uniprot id: F2K3Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

717774:MARME RS14335
gene id: 717774:MARME_RS14335
uniprot id: F2JZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS14875
gene id: 717774:MARME_RS14875
uniprot id: F2K0U3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

717774:MARME RS13005
gene id: 717774:MARME_RS13005
uniprot id: F2JWQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

717774:MARME RS03455
gene id: 717774:MARME_RS03455
uniprot id: F2K1X6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

717774:MARME RS07765
gene id: 717774:MARME_RS07765
uniprot id: F2JY75
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

717774:MARME RS04135
gene id: 717774:MARME_RS04135
uniprot id: F2K344
names: Similarity
messages: Belongs to the TPP enzyme family.

717774:MARME RS01480
gene id: 717774:MARME_RS01480
uniprot id: F2JXU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717774:MARME RS00020
gene id: 717774:MARME_RS00020
uniprot id: F2JUH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

717774:MARME RS14645
gene id: 717774:MARME_RS14645
uniprot id: F2K0Q0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS17425
gene id: 717774:MARME_RS17425
uniprot id: F2JTR1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

717774:MARME RS07020
gene id: 717774:MARME_RS07020
uniprot id: F2JWJ1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS15215
gene id: 717774:MARME_RS15215
uniprot id: F2K1L8
names: Similarity
messages: Belongs to the PhoH family.

717774:MARME RS00590
gene id: 717774:MARME_RS00590
uniprot id: F2JVG4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS14550
gene id: 717774:MARME_RS14550
uniprot id: F2K011
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

717774:MARME RS05525
gene id: 717774:MARME_RS05525
uniprot id: F2JTE9
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

717774:MARME RS12690
gene id: 717774:MARME_RS12690
uniprot id: F2JVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

717774:MARME RS01405
gene id: 717774:MARME_RS01405
uniprot id: F2JX62
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20990
gene id: 717774:MARME_RS20990
uniprot id: F2K1P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS16000
gene id: 717774:MARME_RS16000
uniprot id: F2K311
names: Similarity
messages: Belongs to the MipA/OmpV family.

717774:MARME RS09805
gene id: 717774:MARME_RS09805
uniprot id: F2K2R6
names: Similarity
messages: Belongs to the UPF0045 family.

717774:MARME RS18905
gene id: 717774:MARME_RS18905
uniprot id: F2JWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717774:MARME RS02755
gene id: 717774:MARME_RS02755
uniprot id: F2K0D1
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS14475
gene id: 717774:MARME_RS14475
uniprot id: F2JZZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

717774:MARME RS00620
gene id: 717774:MARME_RS00620
uniprot id: F2JVH0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

717774:MARME RS02550
gene id: 717774:MARME_RS02550
uniprot id: F2K089
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

717774:MARME RS02930
gene id: 717774:MARME_RS02930
uniprot id: F2K131
names: Similarity
messages: Belongs to the SCO1/2 family.

717774:MARME RS12695
gene id: 717774:MARME_RS12695
uniprot id: F2JVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS14015
gene id: 717774:MARME_RS14015
uniprot id: F2JZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS13480
gene id: 717774:MARME_RS13480
uniprot id: F2JY82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS16080
gene id: 717774:MARME_RS16080
uniprot id: F2K322
names: Similarity
messages: Belongs to the UPF0270 family.

717774:MARME RS19850
gene id: 717774:MARME_RS19850
uniprot id: F2JYM9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

717774:MARME RS11625
gene id: 717774:MARME_RS11625
uniprot id: F2JU42
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

717774:MARME RS14790
gene id: 717774:MARME_RS14790
uniprot id: F2K0S5
names: Similarity
messages: Belongs to the thioredoxin family.

717774:MARME RS02750
gene id: 717774:MARME_RS02750
uniprot id: F2K0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

717774:MARME RS19790
gene id: 717774:MARME_RS19790
uniprot id: F2JYL7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

717774:MARME RS00890
gene id: 717774:MARME_RS00890
uniprot id: F2JW94
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

717774:MARME RS05405
gene id: 717774:MARME_RS05405
uniprot id: F2JTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

717774:MARME RS09720
gene id: 717774:MARME_RS09720
uniprot id: F2K2Q0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

717774:MARME RS08830
gene id: 717774:MARME_RS08830
uniprot id: F2K0M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

717774:MARME RS05535
gene id: 717774:MARME_RS05535
uniprot id: F2JTF1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

717774:MARME RS16430
gene id: 717774:MARME_RS16430
uniprot id: F2K3P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

717774:MARME RS16100
gene id: 717774:MARME_RS16100
uniprot id: F2K326
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

717774:MARME RS16775
gene id: 717774:MARME_RS16775
uniprot id: F2K4B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

717774:MARME RS12660
gene id: 717774:MARME_RS12660
uniprot id: F2JVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

717774:MARME RS19965
gene id: 717774:MARME_RS19965
uniprot id: F2JZ98
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS17475
gene id: 717774:MARME_RS17475
uniprot id: F2JTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

717774:MARME RS02200
gene id: 717774:MARME_RS02200
uniprot id: F2JZF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12430
gene id: 717774:MARME_RS12430
uniprot id: F2JVR8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

717774:MARME RS12605
gene id: 717774:MARME_RS12605
uniprot id: F2JVV3
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

717774:MARME RS00135
gene id: 717774:MARME_RS00135
uniprot id: F2JUJ9
names: Similarity
messages: Belongs to the YoeB family.

717774:MARME RS21220
gene id: 717774:MARME_RS21220
uniprot id: F2K1U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS00165
gene id: 717774:MARME_RS00165
uniprot id: F2JUK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS05275
gene id: 717774:MARME_RS05275
uniprot id: F2JT97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS02945
gene id: 717774:MARME_RS02945
uniprot id: F2K134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

717774:MARME RS16625
gene id: 717774:MARME_RS16625
uniprot id: F2K479
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS15840
gene id: 717774:MARME_RS15840
uniprot id: F2K2Y0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717774:MARME RS02270
gene id: 717774:MARME_RS02270
uniprot id: F2JZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

717774:MARME RS06065
gene id: 717774:MARME_RS06065
uniprot id: F2JUQ9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS08900
gene id: 717774:MARME_RS08900
uniprot id: F2K189
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

717774:MARME RS10395
gene id: 717774:MARME_RS10395
uniprot id: F2K3H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

717774:MARME RS17730
gene id: 717774:MARME_RS17730
uniprot id: F2JUC3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

717774:MARME RS06235
gene id: 717774:MARME_RS06235
uniprot id: F2JUU4
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

717774:MARME RS18420
gene id: 717774:MARME_RS18420
uniprot id: F2JVY7
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS06665
gene id: 717774:MARME_RS06665
uniprot id: F2JVP9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS14075
gene id: 717774:MARME_RS14075
uniprot id: F2JZ55
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

717774:MARME RS07125
gene id: 717774:MARME_RS07125
uniprot id: F2JX79
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

717774:MARME RS20730
gene id: 717774:MARME_RS20730
uniprot id: F2K0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

717774:MARME RS08960
gene id: 717774:MARME_RS08960
uniprot id: F2K1A1
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

717774:MARME RS09925
gene id: 717774:MARME_RS09925
uniprot id: F2K2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

717774:MARME RS04030
gene id: 717774:MARME_RS04030
uniprot id: F2K2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

717774:MARME RS00160
gene id: 717774:MARME_RS00160
uniprot id: F2JUK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS10930
gene id: 717774:MARME_RS10930
uniprot id: F2K4M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS12220
gene id: 717774:MARME_RS12220
uniprot id: F2JV11
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS04275
gene id: 717774:MARME_RS04275
uniprot id: F2K368
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS20825
gene id: 717774:MARME_RS20825
uniprot id: F2K0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

717774:MARME RS12760
gene id: 717774:MARME_RS12760
uniprot id: F2JWK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS15300
gene id: 717774:MARME_RS15300
uniprot id: F2K1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

717774:MARME RS14745
gene id: 717774:MARME_RS14745
uniprot id: F2K0S0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS11805
gene id: 717774:MARME_RS11805
uniprot id: F2JU78
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

717774:MARME RS21150
gene id: 717774:MARME_RS21150
uniprot id: F2K1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

717774:MARME RS12855
gene id: 717774:MARME_RS12855
uniprot id: F2JWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

717774:MARME RS19260
gene id: 717774:MARME_RS19260
uniprot id: F2JXP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS15575
gene id: 717774:MARME_RS15575
uniprot id: F2K2D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

717774:MARME RS12530
gene id: 717774:MARME_RS12530
uniprot id: F2JVT8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

717774:MARME RS06370
gene id: 717774:MARME_RS06370
uniprot id: F2JVJ3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

717774:MARME RS06810
gene id: 717774:MARME_RS06810
uniprot id: F2JWE9
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

717774:MARME RS12285
gene id: 717774:MARME_RS12285
uniprot id: F2JV24
names: Similarity
messages: Belongs to the glutamate synthase family.

717774:MARME RS02905
gene id: 717774:MARME_RS02905
uniprot id: F2K126
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS02595
gene id: 717774:MARME_RS02595
uniprot id: F2K098
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

717774:MARME RS18630
gene id: 717774:MARME_RS18630
uniprot id: F2JW27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

717774:MARME RS09645
gene id: 717774:MARME_RS09645
uniprot id: F2K2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

717774:MARME RS09075
gene id: 717774:MARME_RS09075
uniprot id: F2K1C4
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

717774:MARME RS16545
gene id: 717774:MARME_RS16545
uniprot id: F2K463
names: Similarity
messages: Belongs to the TlyA family.

717774:MARME RS15945
gene id: 717774:MARME_RS15945
uniprot id: F2K300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

717774:MARME RS15100
gene id: 717774:MARME_RS15100
uniprot id: F2K1J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

717774:MARME RS10410
gene id: 717774:MARME_RS10410
uniprot id: F2K3X7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS03215
gene id: 717774:MARME_RS03215
uniprot id: F2K175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

717774:MARME RS19300
gene id: 717774:MARME_RS19300
uniprot id: F2JXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

717774:MARME RS11100
gene id: 717774:MARME_RS11100
uniprot id: F2K4R1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

717774:MARME RS17100
gene id: 717774:MARME_RS17100
uniprot id: F2K4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS09990
gene id: 717774:MARME_RS09990
uniprot id: F2K2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

717774:MARME RS07350
gene id: 717774:MARME_RS07350
uniprot id: F2JXC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

717774:MARME RS03580
gene id: 717774:MARME_RS03580
uniprot id: F2K201
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

717774:MARME RS06430
gene id: 717774:MARME_RS06430
uniprot id: F2JVK5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

717774:MARME RS19420
gene id: 717774:MARME_RS19420
uniprot id: F2JXS5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

717774:MARME RS05280
gene id: 717774:MARME_RS05280
uniprot id: F2JT98
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16110
gene id: 717774:MARME_RS16110
uniprot id: F2K3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS12105
gene id: 717774:MARME_RS12105
uniprot id: F2JUZ2
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

717774:MARME RS01200
gene id: 717774:MARME_RS01200
uniprot id: F2JX22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

717774:MARME RS18735
gene id: 717774:MARME_RS18735
uniprot id: F2JWS2
names: Similarity
messages: Belongs to the LOG family.

717774:MARME RS14615
gene id: 717774:MARME_RS14615
uniprot id: F2K0P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

717774:MARME RS01315
gene id: 717774:MARME_RS01315
uniprot id: F2JX45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

717774:MARME RS17005
gene id: 717774:MARME_RS17005
uniprot id: F2K4V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS03775
gene id: 717774:MARME_RS03775
uniprot id: F2K2I9
names: Similarity
messages: Belongs to the aspartokinase family.

717774:MARME RS15165
gene id: 717774:MARME_RS15165
uniprot id: F2K1K8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

717774:MARME RS13905
gene id: 717774:MARME_RS13905
uniprot id: F2JZ21
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

717774:MARME RS15850
gene id: 717774:MARME_RS15850
uniprot id: F2K2Y2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717774:MARME RS07435
gene id: 717774:MARME_RS07435
uniprot id: F2JY11
names: Similarity
messages: Belongs to the UPF0250 family.

717774:MARME RS02630
gene id: 717774:MARME_RS02630
uniprot id: F2K0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS07235
gene id: 717774:MARME_RS07235
uniprot id: F2JXA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

717774:MARME RS16125
gene id: 717774:MARME_RS16125
uniprot id: F2K3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

717774:MARME RS02515
gene id: 717774:MARME_RS02515
uniprot id: F2JZL4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

717774:MARME RS19440
gene id: 717774:MARME_RS19440
uniprot id: F2JXS9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS18425
gene id: 717774:MARME_RS18425
uniprot id: F2JVY8
names: Similarity
messages: Belongs to the VgrG protein family.

717774:MARME RS01065
gene id: 717774:MARME_RS01065
uniprot id: F2JWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

717774:MARME RS05825
gene id: 717774:MARME_RS05825
uniprot id: F2JU07
names: Similarity
messages: Belongs to the Skp family.

717774:MARME RS16385
gene id: 717774:MARME_RS16385
uniprot id: F2K3N3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

717774:MARME RS12035
gene id: 717774:MARME_RS12035
uniprot id: F2JUX8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS20180
gene id: 717774:MARME_RS20180
uniprot id: F2JZD7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

717774:MARME RS10720
gene id: 717774:MARME_RS10720
uniprot id: F2K435
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

717774:MARME RS11230
gene id: 717774:MARME_RS11230
uniprot id: F2JTG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

717774:MARME RS16490
gene id: 717774:MARME_RS16490
uniprot id: F2K452
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

717774:MARME RS00060
gene id: 717774:MARME_RS00060
uniprot id: F2JUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS12345
gene id: 717774:MARME_RS12345
uniprot id: F2JVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS20235
gene id: 717774:MARME_RS20235
uniprot id: F2K019
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

717774:MARME RS11405
gene id: 717774:MARME_RS11405
uniprot id: F2JTK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS17705
gene id: 717774:MARME_RS17705
uniprot id: F2JUB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS04450
gene id: 717774:MARME_RS04450
uniprot id: F2K3Q5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

717774:MARME RS18345
gene id: 717774:MARME_RS18345
uniprot id: F2JVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS12830
gene id: 717774:MARME_RS12830
uniprot id: F2JWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

717774:MARME RS02285
gene id: 717774:MARME_RS02285
uniprot id: F2JZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

717774:MARME RS08940
gene id: 717774:MARME_RS08940
uniprot id: F2K197
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

717774:MARME RS21175
gene id: 717774:MARME_RS21175
uniprot id: F2K1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

717774:MARME RS10675
gene id: 717774:MARME_RS10675
uniprot id: F2K427
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS16500
gene id: 717774:MARME_RS16500
uniprot id: F2K454
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS11060
gene id: 717774:MARME_RS11060
uniprot id: F2K4Q3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS06785
gene id: 717774:MARME_RS06785
uniprot id: F2JWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

717774:MARME RS11275
gene id: 717774:MARME_RS11275
uniprot id: F2JTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

717774:MARME RS07540
gene id: 717774:MARME_RS07540
uniprot id: F2JY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

717774:MARME RS15170
gene id: 717774:MARME_RS15170
uniprot id: F2K1K9
names: Similarity
messages: Belongs to the IMPACT family.

717774:MARME RS12845
gene id: 717774:MARME_RS12845
uniprot id: F2JWM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

717774:MARME RS11620
gene id: 717774:MARME_RS11620
uniprot id: F2JU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS08500
gene id: 717774:MARME_RS08500
uniprot id: F2JZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS11580
gene id: 717774:MARME_RS11580
uniprot id: F2JU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS16050
gene id: 717774:MARME_RS16050
uniprot id: F2K316
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS00605
gene id: 717774:MARME_RS00605
uniprot id: F2JVG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

717774:MARME RS04540
gene id: 717774:MARME_RS04540
uniprot id: F2K3S3
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS14825
gene id: 717774:MARME_RS14825
uniprot id: F2K0T3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

717774:MARME RS19910
gene id: 717774:MARME_RS19910
uniprot id: F2JZ86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS19690
gene id: 717774:MARME_RS19690
uniprot id: F2JYJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS00630
gene id: 717774:MARME_RS00630
uniprot id: F2JVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

717774:MARME RS03680
gene id: 717774:MARME_RS03680
uniprot id: F2K2H0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

717774:MARME RS20610
gene id: 717774:MARME_RS20610
uniprot id: F2K0V3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

717774:MARME RS20045
gene id: 717774:MARME_RS20045
uniprot id: F2JZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS12865
gene id: 717774:MARME_RS12865
uniprot id: F2JWM7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

717774:MARME RS00950
gene id: 717774:MARME_RS00950
uniprot id: F2JWA6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS07280
gene id: 717774:MARME_RS07280
uniprot id: F2JXB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16875
gene id: 717774:MARME_RS16875
uniprot id: F2K4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

717774:MARME RS20670
gene id: 717774:MARME_RS20670
uniprot id: F2K0W5
names: Similarity
messages: Belongs to the GSP E family.

717774:MARME RS07395
gene id: 717774:MARME_RS07395
uniprot id: F2JXD3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

717774:MARME RS00815
gene id: 717774:MARME_RS00815
uniprot id: F2JW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS14435
gene id: 717774:MARME_RS14435
uniprot id: F2JZY7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

717774:MARME RS05630
gene id: 717774:MARME_RS05630
uniprot id: F2JTW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

717774:MARME RS14540
gene id: 717774:MARME_RS14540
uniprot id: F2K009
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

717774:MARME RS08135
gene id: 717774:MARME_RS08135
uniprot id: F2JZ03
names: Similarity
messages: Belongs to the peptidase S58 family.

717774:MARME RS04940
gene id: 717774:MARME_RS04940
uniprot id: F2K4F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717774:MARME RS20505
gene id: 717774:MARME_RS20505
uniprot id: F2K069
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

717774:MARME RS10030
gene id: 717774:MARME_RS10030
uniprot id: F2K3A1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

717774:MARME RS14890
gene id: 717774:MARME_RS14890
uniprot id: F2K0U6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

717774:MARME RS08665
gene id: 717774:MARME_RS08665
uniprot id: F2K0I7
names: Similarity
messages: Belongs to the Gfa family.

717774:MARME RS03560
gene id: 717774:MARME_RS03560
uniprot id: F2K1Z7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

717774:MARME RS14215
gene id: 717774:MARME_RS14215
uniprot id: F2JZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS08510
gene id: 717774:MARME_RS08510
uniprot id: F2JZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS11440
gene id: 717774:MARME_RS11440
uniprot id: F2JTK8
names: Similarity
messages: Belongs to the UPF0178 family.

717774:MARME RS04785
gene id: 717774:MARME_RS04785
uniprot id: F2K3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

717774:MARME RS20945
gene id: 717774:MARME_RS20945
uniprot id: F2K118
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

717774:MARME RS06945
gene id: 717774:MARME_RS06945
uniprot id: F2JWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS06475
gene id: 717774:MARME_RS06475
uniprot id: F2JVL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

717774:MARME RS15085
gene id: 717774:MARME_RS15085
uniprot id: F2K1J2
names: Similarity
messages: Belongs to the YciI family.

717774:MARME RS06140
gene id: 717774:MARME_RS06140
uniprot id: F2JUS4
names: Similarity
messages: Belongs to the SufE family.

717774:MARME RS18410
gene id: 717774:MARME_RS18410
uniprot id: F2JVY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

717774:MARME RS03810
gene id: 717774:MARME_RS03810
uniprot id: F2K2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

717774:MARME RS17695
gene id: 717774:MARME_RS17695
uniprot id: F2JUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS00300
gene id: 717774:MARME_RS00300
uniprot id: F2JVA7
names: Similarity
messages: Belongs to the DapA family.

717774:MARME RS01050
gene id: 717774:MARME_RS01050
uniprot id: F2JWZ6
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

717774:MARME RS11400
gene id: 717774:MARME_RS11400
uniprot id: F2JTK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS15580
gene id: 717774:MARME_RS15580
uniprot id: F2K2D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS17765
gene id: 717774:MARME_RS17765
uniprot id: F2JUD0
names: Similarity
messages: Belongs to the leucine-binding protein family.

717774:MARME RS13000
gene id: 717774:MARME_RS13000
uniprot id: F2JWQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

717774:MARME RS08105
gene id: 717774:MARME_RS08105
uniprot id: F2JYZ7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

717774:MARME RS16055
gene id: 717774:MARME_RS16055
uniprot id: F2K317
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

717774:MARME RS15465
gene id: 717774:MARME_RS15465
uniprot id: F2K2B5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS20920
gene id: 717774:MARME_RS20920
uniprot id: F2K113
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS05710
gene id: 717774:MARME_RS05710
uniprot id: F2JTY4
names: Similarity
messages: Belongs to the SlyX family.

717774:MARME RS14680
gene id: 717774:MARME_RS14680
uniprot id: F2K0Q7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS20755
gene id: 717774:MARME_RS20755
uniprot id: F2K0Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS07595
gene id: 717774:MARME_RS07595
uniprot id: F2JY42
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

717774:MARME RS13720
gene id: 717774:MARME_RS13720
uniprot id: F2JYC8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

717774:MARME RS20445
gene id: 717774:MARME_RS20445
uniprot id: F2K059
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

717774:MARME RS19635
gene id: 717774:MARME_RS19635
uniprot id: F2JYI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS01295
gene id: 717774:MARME_RS01295
uniprot id: F2JX41
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS19480
gene id: 717774:MARME_RS19480
uniprot id: F2JYF6
names: Similarity
messages: Belongs to the GST superfamily.

717774:MARME RS17910
gene id: 717774:MARME_RS17910
uniprot id: F2JUG0
names: Similarity
messages: Belongs to the TrpR family.

717774:MARME RS07745
gene id: 717774:MARME_RS07745
uniprot id: F2JY71
names: Similarity
messages: Belongs to the asparaginase 1 family.

717774:MARME RS09145
gene id: 717774:MARME_RS09145
uniprot id: F2K1D8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

717774:MARME RS13495
gene id: 717774:MARME_RS13495
uniprot id: F2JY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS02520
gene id: 717774:MARME_RS02520
uniprot id: F2JZL5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

717774:MARME RS09650
gene id: 717774:MARME_RS09650
uniprot id: F2K2N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

717774:MARME RS15430
gene id: 717774:MARME_RS15430
uniprot id: F2K2A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

717774:MARME RS20615
gene id: 717774:MARME_RS20615
uniprot id: F2K0V4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS00505
gene id: 717774:MARME_RS00505
uniprot id: F2JVE9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS14700
gene id: 717774:MARME_RS14700
uniprot id: F2K0R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

717774:MARME RS13245
gene id: 717774:MARME_RS13245
uniprot id: F2JXG4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

717774:MARME RS01745
gene id: 717774:MARME_RS01745
uniprot id: F2JXZ8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

717774:MARME RS05255
gene id: 717774:MARME_RS05255
uniprot id: F2JT93
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

717774:MARME RS00500
gene id: 717774:MARME_RS00500
uniprot id: F2JVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS12945
gene id: 717774:MARME_RS12945
uniprot id: F2JWP2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

717774:MARME RS04895
gene id: 717774:MARME_RS04895
uniprot id: F2K4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

717774:MARME RS18070
gene id: 717774:MARME_RS18070
uniprot id: F2JV48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

717774:MARME RS14805
gene id: 717774:MARME_RS14805
uniprot id: F2K0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS14035
gene id: 717774:MARME_RS14035
uniprot id: F2JZ47
names: Similarity
messages: Belongs to the RelE toxin family.

717774:MARME RS01140
gene id: 717774:MARME_RS01140
uniprot id: F2JX10
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS14310
gene id: 717774:MARME_RS14310
uniprot id: F2JZW2
names: Similarity
messages: Belongs to the UPF0231 family.

717774:MARME RS05240
gene id: 717774:MARME_RS05240
uniprot id: F2JT90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

717774:MARME RS16390
gene id: 717774:MARME_RS16390
uniprot id: F2K3N4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

717774:MARME RS09730
gene id: 717774:MARME_RS09730
uniprot id: F2K2Q2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

717774:MARME RS12155
gene id: 717774:MARME_RS12155
uniprot id: F2JUZ9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS09630
gene id: 717774:MARME_RS09630
uniprot id: F2K287
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

717774:MARME RS02960
gene id: 717774:MARME_RS02960
uniprot id: F2K137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

717774:MARME RS19500
gene id: 717774:MARME_RS19500
uniprot id: F2JYG0
names: Similarity
messages: Belongs to the GST superfamily.

717774:MARME RS10130
gene id: 717774:MARME_RS10130
uniprot id: F2K3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS10480
gene id: 717774:MARME_RS10480
uniprot id: F2K3Z1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS05730
gene id: 717774:MARME_RS05730
uniprot id: F2JTY8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

717774:MARME RS07535
gene id: 717774:MARME_RS07535
uniprot id: F2JY31
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS12370
gene id: 717774:MARME_RS12370
uniprot id: F2JVR1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS15550
gene id: 717774:MARME_RS15550
uniprot id: F2K2D2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

717774:MARME RS02255
gene id: 717774:MARME_RS02255
uniprot id: F2JZG3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

717774:MARME RS13585
gene id: 717774:MARME_RS13585
uniprot id: F2JYA2
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS19855
gene id: 717774:MARME_RS19855
uniprot id: F2JZ74
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

717774:MARME RS14635
gene id: 717774:MARME_RS14635
uniprot id: F2K0P8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

717774:MARME RS14350
gene id: 717774:MARME_RS14350
uniprot id: F2JZX0
names: Similarity
messages: Belongs to the peptidase M4 family.

717774:MARME RS07405
gene id: 717774:MARME_RS07405
uniprot id: F2JXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

717774:MARME RS05305
gene id: 717774:MARME_RS05305
uniprot id: F2JTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS01175
gene id: 717774:MARME_RS01175
uniprot id: F2JX17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

717774:MARME RS14625
gene id: 717774:MARME_RS14625
uniprot id: F2K0P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

717774:MARME RS17990
gene id: 717774:MARME_RS17990
uniprot id: F2JV37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

717774:MARME RS11980
gene id: 717774:MARME_RS11980
uniprot id: F2JUW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

717774:MARME RS05355
gene id: 717774:MARME_RS05355
uniprot id: F2JTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

717774:MARME RS08715
gene id: 717774:MARME_RS08715
uniprot id: F2K0J7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

717774:MARME RS06115
gene id: 717774:MARME_RS06115
uniprot id: F2JUR9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

717774:MARME RS08890
gene id: 717774:MARME_RS08890
uniprot id: F2K0N4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

717774:MARME RS02495
gene id: 717774:MARME_RS02495
uniprot id: F2JZL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

717774:MARME RS04405
gene id: 717774:MARME_RS04405
uniprot id: F2K392
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

717774:MARME RS02460
gene id: 717774:MARME_RS02460
uniprot id: F2JZK3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

717774:MARME RS08710
gene id: 717774:MARME_RS08710
uniprot id: F2K0J6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717774:MARME RS17720
gene id: 717774:MARME_RS17720
uniprot id: F2JUC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

717774:MARME RS19035
gene id: 717774:MARME_RS19035
uniprot id: F2JWX8
names: Similarity
messages: Belongs to the glutamine synthetase family.

717774:MARME RS14650
gene id: 717774:MARME_RS14650
uniprot id: F2K0Q2
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS17115
gene id: 717774:MARME_RS17115
uniprot id: F2K4X6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

717774:MARME RS00485
gene id: 717774:MARME_RS00485
uniprot id: F2JVE5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS13020
gene id: 717774:MARME_RS13020
uniprot id: F2JWQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

717774:MARME RS12960
gene id: 717774:MARME_RS12960
uniprot id: F2JWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

717774:MARME RS15010
gene id: 717774:MARME_RS15010
uniprot id: F2K1H7
names: Subcellular Location Annotation
messages: Cytoplasm

717774:MARME RS02210
gene id: 717774:MARME_RS02210
uniprot id: F2JZF4
names: Similarity
messages: Belongs to the DEAD box helicase family.

717774:MARME RS01105
gene id: 717774:MARME_RS01105
uniprot id: F2JX07
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS09425
gene id: 717774:MARME_RS09425
uniprot id: F2K248
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

717774:MARME RS18840
gene id: 717774:MARME_RS18840
uniprot id: F2JWU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

717774:MARME RS05720
gene id: 717774:MARME_RS05720
uniprot id: F2JTY6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717774:MARME RS11325
gene id: 717774:MARME_RS11325
uniprot id: F2JTI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717774:MARME RS03575
gene id: 717774:MARME_RS03575
uniprot id: F2K200
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS20220
gene id: 717774:MARME_RS20220
uniprot id: F2K016
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

717774:MARME RS12785
gene id: 717774:MARME_RS12785
uniprot id: F2JWL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

717774:MARME RS17920
gene id: 717774:MARME_RS17920
uniprot id: F2JUG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS18715
gene id: 717774:MARME_RS18715
uniprot id: F2JW45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

717774:MARME RS03465
gene id: 717774:MARME_RS03465
uniprot id: F2K1X8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

717774:MARME RS09935
gene id: 717774:MARME_RS09935
uniprot id: F2K2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

717774:MARME RS02935
gene id: 717774:MARME_RS02935
uniprot id: F2K132
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

717774:MARME RS02840
gene id: 717774:MARME_RS02840
uniprot id: F2K0E8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

717774:MARME RS09045
gene id: 717774:MARME_RS09045
uniprot id: F2K1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

717774:MARME RS06250
gene id: 717774:MARME_RS06250
uniprot id: F2JUU7
names: Similarity
messages: Belongs to the CobH/CbiC family.

717774:MARME RS06170
gene id: 717774:MARME_RS06170
uniprot id: F2JUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

717774:MARME RS08650
gene id: 717774:MARME_RS08650
uniprot id: F2K0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS12720
gene id: 717774:MARME_RS12720
uniprot id: F2JVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

717774:MARME RS06125
gene id: 717774:MARME_RS06125
uniprot id: F2JUS1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

717774:MARME RS00340
gene id: 717774:MARME_RS00340
uniprot id: F2JVB5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

717774:MARME RS16210
gene id: 717774:MARME_RS16210
uniprot id: F2K3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

717774:MARME RS04985
gene id: 717774:MARME_RS04985
uniprot id: F2K4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

717774:MARME RS07285
gene id: 717774:MARME_RS07285
uniprot id: F2JXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS15035
gene id: 717774:MARME_RS15035
uniprot id: F2K1I2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

717774:MARME RS09110
gene id: 717774:MARME_RS09110
uniprot id: F2K1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

717774:MARME RS11605
gene id: 717774:MARME_RS11605
uniprot id: F2JU38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS14595
gene id: 717774:MARME_RS14595
uniprot id: F2K0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

717774:MARME RS03890
gene id: 717774:MARME_RS03890
uniprot id: F2K2K5
names: Similarity
messages: Belongs to the VgrG protein family.

717774:MARME RS05150
gene id: 717774:MARME_RS05150
uniprot id: F2K4J2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

717774:MARME RS09525
gene id: 717774:MARME_RS09525
uniprot id: F2K268
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

717774:MARME RS13130
gene id: 717774:MARME_RS13130
uniprot id: F2JXE2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS02280
gene id: 717774:MARME_RS02280
uniprot id: F2JZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

717774:MARME RS20245
gene id: 717774:MARME_RS20245
uniprot id: F2K021
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

717774:MARME RS15080
gene id: 717774:MARME_RS15080
uniprot id: F2K1J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

717774:MARME RS19695
gene id: 717774:MARME_RS19695
uniprot id: F2JYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

717774:MARME RS00420
gene id: 717774:MARME_RS00420
uniprot id: F2JVD1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS13535
gene id: 717774:MARME_RS13535
uniprot id: F2JY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

717774:MARME RS13265
gene id: 717774:MARME_RS13265
uniprot id: F2JXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS00075
gene id: 717774:MARME_RS00075
uniprot id: F2JUI7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

717774:MARME RS20230
gene id: 717774:MARME_RS20230
uniprot id: F2K018
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

717774:MARME RS15175
gene id: 717774:MARME_RS15175
uniprot id: F2K1L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

717774:MARME RS17400
gene id: 717774:MARME_RS17400
uniprot id: F2JTQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

717774:MARME RS20960
gene id: 717774:MARME_RS20960
uniprot id: F2K121
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS17285
gene id: 717774:MARME_RS17285
uniprot id: F2JTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS12310
gene id: 717774:MARME_RS12310
uniprot id: F2JV29
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS10820
gene id: 717774:MARME_RS10820
uniprot id: F2K4K5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

717774:MARME RS16560
gene id: 717774:MARME_RS16560
uniprot id: F2K466
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

717774:MARME RS00435
gene id: 717774:MARME_RS00435
uniprot id: F2JVD4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS11435
gene id: 717774:MARME_RS11435
uniprot id: F2JTK7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

717774:MARME RS08845
gene id: 717774:MARME_RS08845
uniprot id: F2K0M4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS01510
gene id: 717774:MARME_RS01510
uniprot id: F2JXV3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

717774:MARME RS01635
gene id: 717774:MARME_RS01635
uniprot id: F2JXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

717774:MARME RS16660
gene id: 717774:MARME_RS16660
uniprot id: F2K486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS01260
gene id: 717774:MARME_RS01260
uniprot id: F2JX34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

717774:MARME RS00965
gene id: 717774:MARME_RS00965
uniprot id: F2JWA9
names: Similarity
messages: Belongs to the Fur family.

717774:MARME RS16175
gene id: 717774:MARME_RS16175
uniprot id: F2K3J0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

717774:MARME RS20975
gene id: 717774:MARME_RS20975
uniprot id: F2K124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS06650
gene id: 717774:MARME_RS06650
uniprot id: F2JVP6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS05805
gene id: 717774:MARME_RS05805
uniprot id: F2JU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

717774:MARME RS09900
gene id: 717774:MARME_RS09900
uniprot id: F2K2T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

717774:MARME RS07805
gene id: 717774:MARME_RS07805
uniprot id: F2JYV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

717774:MARME RS02830
gene id: 717774:MARME_RS02830
uniprot id: F2K0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

717774:MARME RS06900
gene id: 717774:MARME_RS06900
uniprot id: F2JWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS07585
gene id: 717774:MARME_RS07585
uniprot id: F2JY40
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

717774:MARME RS12650
gene id: 717774:MARME_RS12650
uniprot id: F2JVW2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

717774:MARME RS16165
gene id: 717774:MARME_RS16165
uniprot id: F2K3I8
names: Similarity
messages: Belongs to the MotB family.

717774:MARME RS17220
gene id: 717774:MARME_RS17220
uniprot id: F2K4Z7
names: Similarity
messages: Belongs to the DinB family.

717774:MARME RS07785
gene id: 717774:MARME_RS07785
uniprot id: F2JY79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

717774:MARME RS11360
gene id: 717774:MARME_RS11360
uniprot id: F2JTJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS04440
gene id: 717774:MARME_RS04440
uniprot id: F2K3Q3
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

717774:MARME RS18145
gene id: 717774:MARME_RS18145
uniprot id: F2JV63
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

717774:MARME RS14865
gene id: 717774:MARME_RS14865
uniprot id: F2K0U1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

717774:MARME RS21195
gene id: 717774:MARME_RS21195
uniprot id: F2K1T5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS18570
gene id: 717774:MARME_RS18570
uniprot id: F2JW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

717774:MARME RS04095
gene id: 717774:MARME_RS04095
uniprot id: F2K338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS01145
gene id: 717774:MARME_RS01145
uniprot id: F2JX11
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

717774:MARME RS06410
gene id: 717774:MARME_RS06410
uniprot id: F2JVK1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS04970
gene id: 717774:MARME_RS04970
uniprot id: F2K4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

717774:MARME RS11320
gene id: 717774:MARME_RS11320
uniprot id: F2JTI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS05235
gene id: 717774:MARME_RS05235
uniprot id: F2JT89
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

717774:MARME RS05650
gene id: 717774:MARME_RS05650
uniprot id: F2JTX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS12665
gene id: 717774:MARME_RS12665
uniprot id: F2JVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

717774:MARME RS11020
gene id: 717774:MARME_RS11020
uniprot id: F2K4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS00550
gene id: 717774:MARME_RS00550
uniprot id: F2JVF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS08910
gene id: 717774:MARME_RS08910
uniprot id: F2K191
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

717774:MARME RS14660
gene id: 717774:MARME_RS14660
uniprot id: F2K0Q4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

717774:MARME RS05095
gene id: 717774:MARME_RS05095
uniprot id: F2K4I1
names: Similarity
messages: Belongs to the MotB family.

717774:MARME RS14370
gene id: 717774:MARME_RS14370
uniprot id: F2JZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS01755
gene id: 717774:MARME_RS01755
uniprot id: F2JY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS06885
gene id: 717774:MARME_RS06885
uniprot id: F2JWG4
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
messages: Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.

717774:MARME RS18740
gene id: 717774:MARME_RS18740
uniprot id: F2JWS3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

717774:MARME RS07230
gene id: 717774:MARME_RS07230
uniprot id: F2JXA0
names: Subcellular Location Annotation
messages: Cell inner membrane

717774:MARME RS01575
gene id: 717774:MARME_RS01575
uniprot id: F2JXW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717774:MARME RS16450
gene id: 717774:MARME_RS16450
uniprot id: F2K3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

717774:MARME RS12700
gene id: 717774:MARME_RS12700
uniprot id: F2JVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

717774:MARME RS10230
gene id: 717774:MARME_RS10230
uniprot id: F2K3E1
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

717774:MARME RS05210
gene id: 717774:MARME_RS05210
uniprot id: F2JT85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS07190
gene id: 717774:MARME_RS07190
uniprot id: F2JX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

717774:MARME RS13475
gene id: 717774:MARME_RS13475
uniprot id: F2JY81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS12710
gene id: 717774:MARME_RS12710
uniprot id: F2JVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

717774:MARME RS16495
gene id: 717774:MARME_RS16495
uniprot id: F2K453
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

717774:MARME RS21035
gene id: 717774:MARME_RS21035
uniprot id: F2K1Q2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

717774:MARME RS09960
gene id: 717774:MARME_RS09960
uniprot id: F2K2U5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

717774:MARME RS14545
gene id: 717774:MARME_RS14545
uniprot id: F2K010
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

717774:MARME RS09455
gene id: 717774:MARME_RS09455
uniprot id: F2K254
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20745
gene id: 717774:MARME_RS20745
uniprot id: F2K0Y0
names: Similarity
messages: Belongs to the RutC family.

717774:MARME RS19570
gene id: 717774:MARME_RS19570
uniprot id: F2JYH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

717774:MARME RS17825
gene id: 717774:MARME_RS17825
uniprot id: F2JUE2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

717774:MARME RS16650
gene id: 717774:MARME_RS16650
uniprot id: F2K484
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS18850
gene id: 717774:MARME_RS18850
uniprot id: F2JWU6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16140
gene id: 717774:MARME_RS16140
uniprot id: F2K3I3
names: Similarity
messages: Belongs to the type III secretion exporter family.

717774:MARME RS13860
gene id: 717774:MARME_RS13860
uniprot id: F2JZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

717774:MARME RS05025
gene id: 717774:MARME_RS05025
uniprot id: F2K4G7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

717774:MARME RS07345
gene id: 717774:MARME_RS07345
uniprot id: F2JXC3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

717774:MARME RS14610
gene id: 717774:MARME_RS14610
uniprot id: F2K0P3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

717774:MARME RS12890
gene id: 717774:MARME_RS12890
uniprot id: F2JWN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

717774:MARME RS01850
gene id: 717774:MARME_RS01850
uniprot id: F2JYP2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

717774:MARME RS17495
gene id: 717774:MARME_RS17495
uniprot id: F2JTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS03495
gene id: 717774:MARME_RS03495
uniprot id: F2K1Y4
names: Similarity
messages: Belongs to the RecJ family.

717774:MARME RS10355
gene id: 717774:MARME_RS10355
uniprot id: F2K3G6
names: Similarity
messages: Belongs to the DEAD box helicase family.

717774:MARME RS16865
gene id: 717774:MARME_RS16865
uniprot id: F2K4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

717774:MARME RS07770
gene id: 717774:MARME_RS07770
uniprot id: F2JY76
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

717774:MARME RS10925
gene id: 717774:MARME_RS10925
uniprot id: F2K4M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

717774:MARME RS16890
gene id: 717774:MARME_RS16890
uniprot id: F2K4T1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

717774:MARME RS04980
gene id: 717774:MARME_RS04980
uniprot id: F2K4F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

717774:MARME RS18375
gene id: 717774:MARME_RS18375
uniprot id: F2JVX8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

717774:MARME RS17095
gene id: 717774:MARME_RS17095
uniprot id: F2K4X2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

717774:MARME RS02165
gene id: 717774:MARME_RS02165
uniprot id: F2JZE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS05660
gene id: 717774:MARME_RS05660
uniprot id: F2JTX4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

717774:MARME RS21155
gene id: 717774:MARME_RS21155
uniprot id: F2K1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

717774:MARME RS10240
gene id: 717774:MARME_RS10240
uniprot id: F2K3E3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

717774:MARME RS11795
gene id: 717774:MARME_RS11795
uniprot id: F2JU76
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

717774:MARME RS20530
gene id: 717774:MARME_RS20530
uniprot id: F2K072
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

717774:MARME RS15770
gene id: 717774:MARME_RS15770
uniprot id: F2K2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

717774:MARME RS00715
gene id: 717774:MARME_RS00715
uniprot id: F2JW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS10320
gene id: 717774:MARME_RS10320
uniprot id: F2K3F9
names: Similarity
messages: Belongs to the peptidase M1 family.

717774:MARME RS15235
gene id: 717774:MARME_RS15235
uniprot id: F2K1M2
names: Subcellular Location Annotation
messages: Secreted

717774:MARME RS02690
gene id: 717774:MARME_RS02690
uniprot id: F2K0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS10980
gene id: 717774:MARME_RS10980
uniprot id: F2K4N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS16635
gene id: 717774:MARME_RS16635
uniprot id: F2K481
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS15650
gene id: 717774:MARME_RS15650
uniprot id: F2K2F2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

717774:MARME RS00805
gene id: 717774:MARME_RS00805
uniprot id: F2JW77
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

717774:MARME RS17360
gene id: 717774:MARME_RS17360
uniprot id: F2JTP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

717774:MARME RS06850
gene id: 717774:MARME_RS06850
uniprot id: F2JWF7
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS18800
gene id: 717774:MARME_RS18800
uniprot id: F2JWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS15210
gene id: 717774:MARME_RS15210
uniprot id: F2K1L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

717774:MARME RS02715
gene id: 717774:MARME_RS02715
uniprot id: F2K0C3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

717774:MARME RS01155
gene id: 717774:MARME_RS01155
uniprot id: F2JX13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

717774:MARME RS07145
gene id: 717774:MARME_RS07145
uniprot id: F2JX83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS14870
gene id: 717774:MARME_RS14870
uniprot id: F2K0U2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

717774:MARME RS14025
gene id: 717774:MARME_RS14025
uniprot id: F2JZ45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

717774:MARME RS00150
gene id: 717774:MARME_RS00150
uniprot id: F2JUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS06120
gene id: 717774:MARME_RS06120
uniprot id: F2JUS0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

717774:MARME RS17645
gene id: 717774:MARME_RS17645
uniprot id: F2JUA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717774:MARME RS18245
gene id: 717774:MARME_RS18245
uniprot id: F2JV83
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

717774:MARME RS11415
gene id: 717774:MARME_RS11415
uniprot id: F2JTK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

717774:MARME RS17775
gene id: 717774:MARME_RS17775
uniprot id: F2JUD2
names: Similarity
messages: Belongs to the peptidase S41A family.

717774:MARME RS08325
gene id: 717774:MARME_RS08325
uniprot id: F2JZQ2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS11550
gene id: 717774:MARME_RS11550
uniprot id: F2JU27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS08640
gene id: 717774:MARME_RS08640
uniprot id: F2K0I2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS03030
gene id: 717774:MARME_RS03030
uniprot id: F2K143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

717774:MARME RS04960
gene id: 717774:MARME_RS04960
uniprot id: F2K4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

717774:MARME RS16460
gene id: 717774:MARME_RS16460
uniprot id: F2K3P8
names: Similarity
messages: Belongs to the PspA/IM30 family.

717774:MARME RS10100
gene id: 717774:MARME_RS10100
uniprot id: F2K3B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

717774:MARME RS13500
gene id: 717774:MARME_RS13500
uniprot id: F2JY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS01245
gene id: 717774:MARME_RS01245
uniprot id: F2JX31
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

717774:MARME RS07695
gene id: 717774:MARME_RS07695
uniprot id: F2JY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

717774:MARME RS10690
gene id: 717774:MARME_RS10690
uniprot id: F2K430
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

717774:MARME RS14060
gene id: 717774:MARME_RS14060
uniprot id: F2JZ51
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

717774:MARME RS01265
gene id: 717774:MARME_RS01265
uniprot id: F2JX35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

717774:MARME RS03385
gene id: 717774:MARME_RS03385
uniprot id: F2K1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

717774:MARME RS03055
gene id: 717774:MARME_RS03055
uniprot id: F2K148
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

717774:MARME RS12470
gene id: 717774:MARME_RS12470
uniprot id: F2JVS6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS16740
gene id: 717774:MARME_RS16740
uniprot id: F2K4A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

717774:MARME RS04735
gene id: 717774:MARME_RS04735
uniprot id: F2K3W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS05010
gene id: 717774:MARME_RS05010
uniprot id: F2K4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

717774:MARME RS10370
gene id: 717774:MARME_RS10370
uniprot id: F2K3G9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

717774:MARME RS19135
gene id: 717774:MARME_RS19135
uniprot id: F2JXL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

717774:MARME RS05670
gene id: 717774:MARME_RS05670
uniprot id: F2JTX6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

717774:MARME RS05070
gene id: 717774:MARME_RS05070
uniprot id: F2K4H6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

717774:MARME RS03065
gene id: 717774:MARME_RS03065
uniprot id: F2K150
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

717774:MARME RS05820
gene id: 717774:MARME_RS05820
uniprot id: F2JU06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

717774:MARME RS02970
gene id: 717774:MARME_RS02970
uniprot id: F2K139
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS14960
gene id: 717774:MARME_RS14960
uniprot id: F2K1G7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

717774:MARME RS00085
gene id: 717774:MARME_RS00085
uniprot id: F2JUI9
names: Similarity
messages: Belongs to the DprA/Smf family.

717774:MARME RS06335
gene id: 717774:MARME_RS06335
uniprot id: F2JVI4
names: Similarity
messages: Belongs to the asparagine synthetase family.

717774:MARME RS00985
gene id: 717774:MARME_RS00985
uniprot id: F2JWB4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

717774:MARME RS16910
gene id: 717774:MARME_RS16910
uniprot id: F2K4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

717774:MARME RS08130
gene id: 717774:MARME_RS08130
uniprot id: F2JZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS11450
gene id: 717774:MARME_RS11450
uniprot id: F2JTL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

717774:MARME RS10605
gene id: 717774:MARME_RS10605
uniprot id: F2K415
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS16965
gene id: 717774:MARME_RS16965
uniprot id: F2K4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

717774:MARME RS01495
gene id: 717774:MARME_RS01495
uniprot id: F2JXV0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

717774:MARME RS01350
gene id: 717774:MARME_RS01350
uniprot id: F2JX52
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

717774:MARME RS16670
gene id: 717774:MARME_RS16670
uniprot id: F2K488
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

717774:MARME RS14480
gene id: 717774:MARME_RS14480
uniprot id: F2JZZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

717774:MARME RS17755
gene id: 717774:MARME_RS17755
uniprot id: F2JUC8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS03085
gene id: 717774:MARME_RS03085
uniprot id: F2K154
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS21040
gene id: 717774:MARME_RS21040
uniprot id: F2K1Q3
names: Similarity
messages: Belongs to the SufE family.

717774:MARME RS20415
gene id: 717774:MARME_RS20415
uniprot id: F2K053
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

717774:MARME RS08930
gene id: 717774:MARME_RS08930
uniprot id: F2K195
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

717774:MARME RS17175
gene id: 717774:MARME_RS17175
uniprot id: F2K4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS12525
gene id: 717774:MARME_RS12525
uniprot id: F2JVT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS08745
gene id: 717774:MARME_RS08745
uniprot id: F2K0K3
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS17510
gene id: 717774:MARME_RS17510
uniprot id: F2JTS8
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS01150
gene id: 717774:MARME_RS01150
uniprot id: F2JX12
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

717774:MARME RS18590
gene id: 717774:MARME_RS18590
uniprot id: F2JW19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

717774:MARME RS07445
gene id: 717774:MARME_RS07445
uniprot id: F2JY13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

717774:MARME RS07905
gene id: 717774:MARME_RS07905
uniprot id: F2JYV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717774:MARME RS20680
gene id: 717774:MARME_RS20680
uniprot id: F2K0W7
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS20925
gene id: 717774:MARME_RS20925
uniprot id: F2K114
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS17460
gene id: 717774:MARME_RS17460
uniprot id: F2JTR8
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

717774:MARME RS09930
gene id: 717774:MARME_RS09930
uniprot id: F2K2U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

717774:MARME RS14240
gene id: 717774:MARME_RS14240
uniprot id: F2JZU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

717774:MARME RS09050
gene id: 717774:MARME_RS09050
uniprot id: F2K1B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

717774:MARME RS05900
gene id: 717774:MARME_RS05900
uniprot id: F2JU20
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

717774:MARME RS16595
gene id: 717774:MARME_RS16595
uniprot id: F2K473
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS11420
gene id: 717774:MARME_RS11420
uniprot id: F2JTK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS03070
gene id: 717774:MARME_RS03070
uniprot id: F2K151
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

717774:MARME RS02555
gene id: 717774:MARME_RS02555
uniprot id: F2K090
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS07205
gene id: 717774:MARME_RS07205
uniprot id: F2JX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS00425
gene id: 717774:MARME_RS00425
uniprot id: F2JVD2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

717774:MARME RS12965
gene id: 717774:MARME_RS12965
uniprot id: F2JWP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

717774:MARME RS20800
gene id: 717774:MARME_RS20800
uniprot id: F2K0Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

717774:MARME RS09875
gene id: 717774:MARME_RS09875
uniprot id: F2K2T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

717774:MARME RS08125
gene id: 717774:MARME_RS08125
uniprot id: F2JZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS09855
gene id: 717774:MARME_RS09855
uniprot id: F2K2S6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

717774:MARME RS01640
gene id: 717774:MARME_RS01640
uniprot id: F2JXX7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

717774:MARME RS03445
gene id: 717774:MARME_RS03445
uniprot id: F2K1X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

717774:MARME RS10450
gene id: 717774:MARME_RS10450
uniprot id: F2K3Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS01370
gene id: 717774:MARME_RS01370
uniprot id: F2JX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS16915
gene id: 717774:MARME_RS16915
uniprot id: F2K4T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

717774:MARME RS17955
gene id: 717774:MARME_RS17955
uniprot id: F2JUG9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS10270
gene id: 717774:MARME_RS10270
uniprot id: F2K3E9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS08050
gene id: 717774:MARME_RS08050
uniprot id: F2JYY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

717774:MARME RS19170
gene id: 717774:MARME_RS19170
uniprot id: F2JXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS17875
gene id: 717774:MARME_RS17875
uniprot id: F2JUF3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

717774:MARME RS03765
gene id: 717774:MARME_RS03765
uniprot id: F2K2I7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

717774:MARME RS16925
gene id: 717774:MARME_RS16925
uniprot id: F2K4T8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

717774:MARME RS06755
gene id: 717774:MARME_RS06755
uniprot id: F2JWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

717774:MARME RS08690
gene id: 717774:MARME_RS08690
uniprot id: F2K0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS11615
gene id: 717774:MARME_RS11615
uniprot id: F2JU40
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS12820
gene id: 717774:MARME_RS12820
uniprot id: F2JWL8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

717774:MARME RS04620
gene id: 717774:MARME_RS04620
uniprot id: F2K3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS03435
gene id: 717774:MARME_RS03435
uniprot id: F2K1X2
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS07575
gene id: 717774:MARME_RS07575
uniprot id: F2JY39
names: Similarity
messages: Belongs to the citrate synthase family.

717774:MARME RS05795
gene id: 717774:MARME_RS05795
uniprot id: F2JU01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

717774:MARME RS02190
gene id: 717774:MARME_RS02190
uniprot id: F2JZF0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

717774:MARME RS01990
gene id: 717774:MARME_RS01990
uniprot id: F2JYR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

717774:MARME RS17065
gene id: 717774:MARME_RS17065
uniprot id: F2K4W6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717774:MARME RS16935
gene id: 717774:MARME_RS16935
uniprot id: F2K4U0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

717774:MARME RS21200
gene id: 717774:MARME_RS21200
uniprot id: F2K1T6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

717774:MARME RS05770
gene id: 717774:MARME_RS05770
uniprot id: F2JTZ6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

717774:MARME RS04730
gene id: 717774:MARME_RS04730
uniprot id: F2K3W0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717774:MARME RS10050
gene id: 717774:MARME_RS10050
uniprot id: F2K3A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

717774:MARME RS15525
gene id: 717774:MARME_RS15525
uniprot id: F2K2C7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

717774:MARME RS08100
gene id: 717774:MARME_RS08100
uniprot id: F2JYZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS16215
gene id: 717774:MARME_RS16215
uniprot id: F2K3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

717774:MARME RS16990
gene id: 717774:MARME_RS16990
uniprot id: F2K4V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

717774:MARME RS10760
gene id: 717774:MARME_RS10760
uniprot id: F2K443
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS15615
gene id: 717774:MARME_RS15615
uniprot id: F2K2E5
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

717774:MARME RS09005
gene id: 717774:MARME_RS09005
uniprot id: F2K1B0
names: Similarity
messages: Belongs to the BolA/IbaG family.

717774:MARME RS13145
gene id: 717774:MARME_RS13145
uniprot id: F2JXE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS11105
gene id: 717774:MARME_RS11105
uniprot id: F2K4R2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS07760
gene id: 717774:MARME_RS07760
uniprot id: F2JY74
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

717774:MARME RS08245
gene id: 717774:MARME_RS08245
uniprot id: F2JZN6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS10745
gene id: 717774:MARME_RS10745
uniprot id: F2K440
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

717774:MARME RS17410
gene id: 717774:MARME_RS17410
uniprot id: F2JTQ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717774:MARME RS10245
gene id: 717774:MARME_RS10245
uniprot id: F2K3E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

717774:MARME RS10095
gene id: 717774:MARME_RS10095
uniprot id: F2K3B4
names: Similarity
messages: Belongs to the fabD family.

717774:MARME RS06200
gene id: 717774:MARME_RS06200
uniprot id: F2JUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

717774:MARME RS18220
gene id: 717774:MARME_RS18220
uniprot id: F2JV78
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS06425
gene id: 717774:MARME_RS06425
uniprot id: F2JVK4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

717774:MARME RS08770
gene id: 717774:MARME_RS08770
uniprot id: F2K0K8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

717774:MARME RS02260
gene id: 717774:MARME_RS02260
uniprot id: F2JZG4
names: Similarity
messages: Belongs to the NAPRTase family.

717774:MARME RS12450
gene id: 717774:MARME_RS12450
uniprot id: F2JVS2
names: Similarity
messages: Belongs to the universal stress protein A family.

717774:MARME RS20785
gene id: 717774:MARME_RS20785
uniprot id: F2K0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

717774:MARME RS10365
gene id: 717774:MARME_RS10365
uniprot id: F2K3G8
names: Similarity
messages: Belongs to the CvfB family.

717774:MARME RS13220
gene id: 717774:MARME_RS13220
uniprot id: F2JXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

717774:MARME RS14195
gene id: 717774:MARME_RS14195
uniprot id: F2JZ73
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

717774:MARME RS05160
gene id: 717774:MARME_RS05160
uniprot id: F2K4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

717774:MARME RS00685
gene id: 717774:MARME_RS00685
uniprot id: F2JW53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

717774:MARME RS10555
gene id: 717774:MARME_RS10555
uniprot id: F2K407
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

717774:MARME RS00095
gene id: 717774:MARME_RS00095
uniprot id: F2JUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

717774:MARME RS12070
gene id: 717774:MARME_RS12070
uniprot id: F2JUY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS17465
gene id: 717774:MARME_RS17465
uniprot id: F2JTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

717774:MARME RS09740
gene id: 717774:MARME_RS09740
uniprot id: F2K2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

717774:MARME RS08520
gene id: 717774:MARME_RS08520
uniprot id: F2JZT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

717774:MARME RS18160
gene id: 717774:MARME_RS18160
uniprot id: F2JV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

717774:MARME RS00610
gene id: 717774:MARME_RS00610
uniprot id: F2JVG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

717774:MARME RS09660
gene id: 717774:MARME_RS09660
uniprot id: F2K2N8
names: Similarity
messages: Belongs to the tannase family.

717774:MARME RS02800
gene id: 717774:MARME_RS02800
uniprot id: F2K0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

717774:MARME RS14740
gene id: 717774:MARME_RS14740
uniprot id: F2K0R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

717774:MARME RS16480
gene id: 717774:MARME_RS16480
uniprot id: F2K450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

717774:MARME RS01475
gene id: 717774:MARME_RS01475
uniprot id: F2JXU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

717774:MARME RS08205
gene id: 717774:MARME_RS08205
uniprot id: F2JZM8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

717774:MARME RS01320
gene id: 717774:MARME_RS01320
uniprot id: F2JX46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

717774:MARME RS01255
gene id: 717774:MARME_RS01255
uniprot id: F2JX33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

717774:MARME RS05500
gene id: 717774:MARME_RS05500
uniprot id: F2JTE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

717774:MARME RS08545
gene id: 717774:MARME_RS08545
uniprot id: F2K0G4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

717774:MARME RS16400
gene id: 717774:MARME_RS16400
uniprot id: F2K3N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

717774:MARME RS02220
gene id: 717774:MARME_RS02220
uniprot id: F2JZF6
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS09065
gene id: 717774:MARME_RS09065
uniprot id: F2K1C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

717774:MARME RS08875
gene id: 717774:MARME_RS08875
uniprot id: F2K0N0
names: Similarity
messages: Belongs to the YkuD family.

717774:MARME RS00090
gene id: 717774:MARME_RS00090
uniprot id: F2JUJ0
names: Similarity
messages: Belongs to the HSP15 family.

717774:MARME RS02610
gene id: 717774:MARME_RS02610
uniprot id: F2K0A1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

717774:MARME RS13505
gene id: 717774:MARME_RS13505
uniprot id: F2JY87
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS11445
gene id: 717774:MARME_RS11445
uniprot id: F2JTK9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

717774:MARME RS19335
gene id: 717774:MARME_RS19335
uniprot id: F2JXQ8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

717774:MARME RS02195
gene id: 717774:MARME_RS02195
uniprot id: F2JZF1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

717774:MARME RS05490
gene id: 717774:MARME_RS05490
uniprot id: F2JTE2
names: Subcellular Location Annotation
messages: Secreted

717774:MARME RS15095
gene id: 717774:MARME_RS15095
uniprot id: F2K1J4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

717774:MARME RS17440
gene id: 717774:MARME_RS17440
uniprot id: F2JTR4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

717774:MARME RS20250
gene id: 717774:MARME_RS20250
uniprot id: F2K022
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS07160
gene id: 717774:MARME_RS07160
uniprot id: F2JX86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS13885
gene id: 717774:MARME_RS13885
uniprot id: F2JZ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

717774:MARME RS05980
gene id: 717774:MARME_RS05980
uniprot id: F2JUP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

717774:MARME RS04025
gene id: 717774:MARME_RS04025
uniprot id: F2K2N2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

717774:MARME RS13870
gene id: 717774:MARME_RS13870
uniprot id: F2JZ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

717774:MARME RS18315
gene id: 717774:MARME_RS18315
uniprot id: F2JV96
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS05035
gene id: 717774:MARME_RS05035
uniprot id: F2K4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

717774:MARME RS19060
gene id: 717774:MARME_RS19060
uniprot id: F2JWY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS15025
gene id: 717774:MARME_RS15025
uniprot id: F2K1I0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS16105
gene id: 717774:MARME_RS16105
uniprot id: F2K3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

717774:MARME RS02480
gene id: 717774:MARME_RS02480
uniprot id: F2JZK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS01695
gene id: 717774:MARME_RS01695
uniprot id: F2JXY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS04600
gene id: 717774:MARME_RS04600
uniprot id: F2K3T6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

717774:MARME RS01645
gene id: 717774:MARME_RS01645
uniprot id: F2JXX8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

717774:MARME RS17185
gene id: 717774:MARME_RS17185
uniprot id: F2K4Z0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

717774:MARME RS08265
gene id: 717774:MARME_RS08265
uniprot id: F2JZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

717774:MARME RS09890
gene id: 717774:MARME_RS09890
uniprot id: F2K2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

717774:MARME RS13790
gene id: 717774:MARME_RS13790
uniprot id: F2JYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS06965
gene id: 717774:MARME_RS06965
uniprot id: F2JWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

717774:MARME RS01055
gene id: 717774:MARME_RS01055
uniprot id: F2JWZ7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

717774:MARME RS14165
gene id: 717774:MARME_RS14165
uniprot id: F2JZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

717774:MARME RS17070
gene id: 717774:MARME_RS17070
uniprot id: F2K4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717774:MARME RS11140
gene id: 717774:MARME_RS11140
uniprot id: F2K4R9
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS11560
gene id: 717774:MARME_RS11560
uniprot id: F2JU29
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

717774:MARME RS18770
gene id: 717774:MARME_RS18770
uniprot id: F2JWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

717774:MARME RS19055
gene id: 717774:MARME_RS19055
uniprot id: F2JWY2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717774:MARME RS08315
gene id: 717774:MARME_RS08315
uniprot id: F2JZQ0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

717774:MARME RS10300
gene id: 717774:MARME_RS10300
uniprot id: F2K3F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS01170
gene id: 717774:MARME_RS01170
uniprot id: F2JX16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

717774:MARME RS04900
gene id: 717774:MARME_RS04900
uniprot id: F2K4E4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

717774:MARME RS01340
gene id: 717774:MARME_RS01340
uniprot id: F2JX50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

717774:MARME RS19285
gene id: 717774:MARME_RS19285
uniprot id: F2JXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

717774:MARME RS02160
gene id: 717774:MARME_RS02160
uniprot id: F2JYV1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

717774:MARME RS20815
gene id: 717774:MARME_RS20815
uniprot id: F2K0Z4
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

717774:MARME RS01585
gene id: 717774:MARME_RS01585
uniprot id: F2JXW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

717774:MARME RS21210
gene id: 717774:MARME_RS21210
uniprot id: F2K1T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

717774:MARME RS05640
gene id: 717774:MARME_RS05640
uniprot id: F2JTX0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

717774:MARME RS00080
gene id: 717774:MARME_RS00080
uniprot id: F2JUI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

717774:MARME RS04260
gene id: 717774:MARME_RS04260
uniprot id: F2K365
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS18595
gene id: 717774:MARME_RS18595
uniprot id: F2JW20
names: Similarity
messages: Belongs to the YggT family.

717774:MARME RS08580
gene id: 717774:MARME_RS08580
uniprot id: F2K0H1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

717774:MARME RS00875
gene id: 717774:MARME_RS00875
uniprot id: F2JW91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

717774:MARME RS14385
gene id: 717774:MARME_RS14385
uniprot id: F2JZX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS02540
gene id: 717774:MARME_RS02540
uniprot id: F2K087
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

717774:MARME RS17180
gene id: 717774:MARME_RS17180
uniprot id: F2K4Y9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

717774:MARME RS03060
gene id: 717774:MARME_RS03060
uniprot id: F2K149
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

717774:MARME RS08115
gene id: 717774:MARME_RS08115
uniprot id: F2JYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

717774:MARME RS17470
gene id: 717774:MARME_RS17470
uniprot id: F2JTS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

717774:MARME RS08070
gene id: 717774:MARME_RS08070
uniprot id: F2JYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS05380
gene id: 717774:MARME_RS05380
uniprot id: F2JTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

717774:MARME RS08675
gene id: 717774:MARME_RS08675
uniprot id: F2K0I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

717774:MARME RS00205
gene id: 717774:MARME_RS00205
uniprot id: F2JUL3
names: Similarity
messages: Belongs to the DapA family.

717774:MARME RS18085
gene id: 717774:MARME_RS18085
uniprot id: F2JV51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

717774:MARME RS01775
gene id: 717774:MARME_RS01775
uniprot id: F2JY03
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

717774:MARME RS13090
gene id: 717774:MARME_RS13090
uniprot id: F2JWS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717774:MARME RS03360
gene id: 717774:MARME_RS03360
uniprot id: F2K1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

717774:MARME RS03630
gene id: 717774:MARME_RS03630
uniprot id: F2K211
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

717774:MARME RS10485
gene id: 717774:MARME_RS10485
uniprot id: F2K3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

717774:MARME RS04160
gene id: 717774:MARME_RS04160
uniprot id: F2K349
names: Similarity
messages: Belongs to the hyi family.

717774:MARME RS10105
gene id: 717774:MARME_RS10105
uniprot id: F2K3B6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

717774:MARME RS16240
gene id: 717774:MARME_RS16240
uniprot id: F2K3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

717774:MARME RS10510
gene id: 717774:MARME_RS10510
uniprot id: F2K3Z7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

717774:MARME RS20340
gene id: 717774:MARME_RS20340
uniprot id: F2K040
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

717774:MARME RS10935
gene id: 717774:MARME_RS10935
uniprot id: F2K4M8
names: Similarity
messages: Belongs to the GcvT family.

717774:MARME RS01515
gene id: 717774:MARME_RS01515
uniprot id: F2JXV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

717774:MARME RS22220
gene id: 717774:MARME_RS22220
uniprot id: F2JTM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS08475
gene id: 717774:MARME_RS08475
uniprot id: F2JZT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS10975
gene id: 717774:MARME_RS10975
uniprot id: F2K4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

717774:MARME RS05865
gene id: 717774:MARME_RS05865
uniprot id: F2JU15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

717774:MARME RS01250
gene id: 717774:MARME_RS01250
uniprot id: F2JX32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

717774:MARME RS13785
gene id: 717774:MARME_RS13785
uniprot id: F2JYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717774:MARME RS12490
gene id: 717774:MARME_RS12490
uniprot id: F2JVT0
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS00315
gene id: 717774:MARME_RS00315
uniprot id: F2JVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS12085
gene id: 717774:MARME_RS12085
uniprot id: F2JUY8
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

717774:MARME RS09010
gene id: 717774:MARME_RS09010
uniprot id: F2K1B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717774:MARME RS09265
gene id: 717774:MARME_RS09265
uniprot id: F2K1G3
names: Similarity
messages: Belongs to the peptidase S14 family.

717774:MARME RS08075
gene id: 717774:MARME_RS08075
uniprot id: F2JYZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

717774:MARME RS11810
gene id: 717774:MARME_RS11810
uniprot id: F2JU79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS19290
gene id: 717774:MARME_RS19290
uniprot id: F2JXP8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717774:MARME RS18910
gene id: 717774:MARME_RS18910
uniprot id: F2JWV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

717774:MARME RS02215
gene id: 717774:MARME_RS02215
uniprot id: F2JZF5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS02420
gene id: 717774:MARME_RS02420
uniprot id: F2JZJ5
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS06390
gene id: 717774:MARME_RS06390
uniprot id: F2JVJ7
names: Cofactor
messages: Can also use Mn(2+) ion.

717774:MARME RS02560
gene id: 717774:MARME_RS02560
uniprot id: F2K091
names: Similarity
messages: Belongs to the UPF0758 family.

717774:MARME RS01725
gene id: 717774:MARME_RS01725
uniprot id: F2JXZ4
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS19070
gene id: 717774:MARME_RS19070
uniprot id: F2JWY5
names: Similarity
messages: Belongs to the agmatine deiminase family.

717774:MARME RS04020
gene id: 717774:MARME_RS04020
uniprot id: F2K2N1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

717774:MARME RS19950
gene id: 717774:MARME_RS19950
uniprot id: F2JZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

717774:MARME RS16225
gene id: 717774:MARME_RS16225
uniprot id: F2K3K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

717774:MARME RS20655
gene id: 717774:MARME_RS20655
uniprot id: F2K0W2
names: Similarity
messages: Belongs to the bacterial secretin family.

717774:MARME RS16170
gene id: 717774:MARME_RS16170
uniprot id: F2K3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

717774:MARME RS17785
gene id: 717774:MARME_RS17785
uniprot id: F2JUD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

717774:MARME RS04265
gene id: 717774:MARME_RS04265
uniprot id: F2K366
names: Subcellular Location Annotation
messages: Membrane

717774:MARME RS13015
gene id: 717774:MARME_RS13015
uniprot id: F2JWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

717774:MARME RS00495
gene id: 717774:MARME_RS00495
uniprot id: F2JVE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS06870
gene id: 717774:MARME_RS06870
uniprot id: F2JWG1
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

717774:MARME RS14860
gene id: 717774:MARME_RS14860
uniprot id: F2K0U0
names: Similarity
messages: Belongs to the UPF0246 family.

717774:MARME RS12950
gene id: 717774:MARME_RS12950
uniprot id: F2JWP3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

717774:MARME RS05420
gene id: 717774:MARME_RS05420
uniprot id: F2JTC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717774:MARME RS02685
gene id: 717774:MARME_RS02685
uniprot id: F2K0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

717774:MARME RS11225
gene id: 717774:MARME_RS11225
uniprot id: F2JTG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

717774:MARME RS01230
gene id: 717774:MARME_RS01230
uniprot id: F2JX28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

717774:MARME RS07075
gene id: 717774:MARME_RS07075
uniprot id: F2JX68
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717774:MARME RS14445
gene id: 717774:MARME_RS14445
uniprot id: F2JZY9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

717774:MARME RS15520
gene id: 717774:MARME_RS15520
uniprot id: F2K2C6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

717774:MARME RS04925
gene id: 717774:MARME_RS04925
uniprot id: F2K4E9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

717774:MARME RS08345
gene id: 717774:MARME_RS08345
uniprot id: F2JZQ6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

717774:MARME RS06205
gene id: 717774:MARME_RS06205
uniprot id: F2JUT7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

717774:MARME RS05190
gene id: 717774:MARME_RS05190
uniprot id: F2JT81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

717774:MARME RS08755
gene id: 717774:MARME_RS08755
uniprot id: F2K0K5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717774:MARME RS04395
gene id: 717774:MARME_RS04395
uniprot id: F2K390
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

717774:MARME RS21255
gene id: 717774:MARME_RS21255
uniprot id: F2JXV6
names: Similarity
messages: Belongs to the peptidase S8 family.

717774:MARME RS15715
gene id: 717774:MARME_RS15715
uniprot id: F2K2G5
names: Similarity
messages: Belongs to the phosphorylase b kinase regulatory chain family.

717774:MARME RS02885
gene id: 717774:MARME_RS02885
uniprot id: F2K0F7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

717774:MARME RS13930
gene id: 717774:MARME_RS13930
uniprot id: F2JZ26
names: Similarity
messages: Belongs to the acetyltransferase YopJ family.

717774:MARME RS14465
gene id: 717774:MARME_RS14465
uniprot id: F2JZZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
messages: Homotetramer; dimer of dimers.

717774:MARME RS07375
gene id: 717774:MARME_RS07375
uniprot id: F2JXC9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

717774:MARME RS06860
gene id: 717774:MARME_RS06860
uniprot id: F2JWF9
names: Similarity
messages: Belongs to the peptidase S49 family.

717774:MARME RS10020
gene id: 717774:MARME_RS10020
uniprot id: F2K399
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

717774:MARME RS06685
gene id: 717774:MARME_RS06685
uniprot id: F2JWC4
names: Similarity
messages: Belongs to the universal stress protein A family.

717774:MARME RS07480
gene id: 717774:MARME_RS07480
uniprot id: F2JY20
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

717774:MARME RS19685
gene id: 717774:MARME_RS19685
uniprot id: F2JYJ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.