716544:WCW RS09225
gene id: 716544:WCW_RS09225
uniprot id: D6YT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

716544:WCW RS00965
gene id: 716544:WCW_RS00965
uniprot id: D6YTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

716544:WCW RS01480
gene id: 716544:WCW_RS01480
uniprot id: D6YU72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

716544:WCW RS04220
gene id: 716544:WCW_RS04220
uniprot id: D6YVS7
names: Similarity
messages: Belongs to the LOG family.

716544:WCW RS02480
gene id: 716544:WCW_RS02480
uniprot id: D6YUS7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

716544:WCW RS03285
gene id: 716544:WCW_RS03285
uniprot id: D6YV88
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS05915
gene id: 716544:WCW_RS05915
uniprot id: D6YWS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

716544:WCW RS08775
gene id: 716544:WCW_RS08775
uniprot id: D6YSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

716544:WCW RS04195
gene id: 716544:WCW_RS04195
uniprot id: D6YVS2
names: Similarity
messages: Belongs to the elongation factor P family.

716544:WCW RS03270
gene id: 716544:WCW_RS03270
uniprot id: D6YV85
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

716544:WCW RS07275
gene id: 716544:WCW_RS07275
uniprot id: D6YS12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

716544:WCW RS03505
gene id: 716544:WCW_RS03505
uniprot id: D6YVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

716544:WCW RS07380
gene id: 716544:WCW_RS07380
uniprot id: D6YS34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS04075
gene id: 716544:WCW_RS04075
uniprot id: D6YVP8
names: Similarity
messages: Belongs to the UPF0162 family.

716544:WCW RS01165
gene id: 716544:WCW_RS01165
uniprot id: D6YU09
names: Similarity
messages: Belongs to the EUO family.

716544:WCW RS03955
gene id: 716544:WCW_RS03955
uniprot id: D6YVM5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05540
gene id: 716544:WCW_RS05540
uniprot id: D6YWJ2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

716544:WCW RS00975
gene id: 716544:WCW_RS00975
uniprot id: D6YTW7
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role analogous to that of eukaryotic histone proteins.

716544:WCW RS00495
gene id: 716544:WCW_RS00495
uniprot id: D6YTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

716544:WCW RS07940
gene id: 716544:WCW_RS07940
uniprot id: D6YSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

716544:WCW RS01260
gene id: 716544:WCW_RS01260
uniprot id: D6YU29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

716544:WCW RS06865
gene id: 716544:WCW_RS06865
uniprot id: D6YRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

716544:WCW RS06895
gene id: 716544:WCW_RS06895
uniprot id: D6YRT5
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03925
gene id: 716544:WCW_RS03925
uniprot id: D6YVL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05030
gene id: 716544:WCW_RS05030
uniprot id: D6YW85
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS01025
gene id: 716544:WCW_RS01025
uniprot id: D6YTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

716544:WCW RS03075
gene id: 716544:WCW_RS03075
uniprot id: D6YV49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

716544:WCW RS00575
gene id: 716544:WCW_RS00575
uniprot id: D6YTN6
names: Similarity
messages: Belongs to the Pal lipoprotein family.

716544:WCW RS08170
gene id: 716544:WCW_RS08170
uniprot id: D6YSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

716544:WCW RS03425
gene id: 716544:WCW_RS03425
uniprot id: D6YVB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

716544:WCW RS08220
gene id: 716544:WCW_RS08220
uniprot id: D6YSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

716544:WCW RS04200
gene id: 716544:WCW_RS04200
uniprot id: D6YVS3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

716544:WCW RS05800
gene id: 716544:WCW_RS05800
uniprot id: D6YWP8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

716544:WCW RS06795
gene id: 716544:WCW_RS06795
uniprot id: D6YRR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

716544:WCW RS05225
gene id: 716544:WCW_RS05225
uniprot id: D6YWC5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

716544:WCW RS02835
gene id: 716544:WCW_RS02835
uniprot id: D6YV00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

716544:WCW RS05860
gene id: 716544:WCW_RS05860
uniprot id: D6YWR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS01845
gene id: 716544:WCW_RS01845
uniprot id: D6YUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

716544:WCW RS05580
gene id: 716544:WCW_RS05580
uniprot id: D6YWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

716544:WCW RS05760
gene id: 716544:WCW_RS05760
uniprot id: D6YWN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

716544:WCW RS02825
gene id: 716544:WCW_RS02825
uniprot id: D6YUZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

716544:WCW RS05930
gene id: 716544:WCW_RS05930
uniprot id: D6YWS4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

716544:WCW RS10370
gene id: 716544:WCW_RS10370
uniprot id: D6YUC5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

716544:WCW RS00555
gene id: 716544:WCW_RS00555
uniprot id: D6YTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

716544:WCW RS07005
gene id: 716544:WCW_RS07005
uniprot id: D6YRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

716544:WCW RS08880
gene id: 716544:WCW_RS08880
uniprot id: D6YSZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

716544:WCW RS06375
gene id: 716544:WCW_RS06375
uniprot id: D6YRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

716544:WCW RS08640
gene id: 716544:WCW_RS08640
uniprot id: D6YSU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS09290
gene id: 716544:WCW_RS09290
uniprot id: D6YT74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

716544:WCW RS00550
gene id: 716544:WCW_RS00550
uniprot id: D6YTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

716544:WCW RS00095
gene id: 716544:WCW_RS00095
uniprot id: D6YTD9
names: Similarity
messages: Belongs to the UPF0137 (pGP6-D) family.

716544:WCW RS01470
gene id: 716544:WCW_RS01470
uniprot id: D6YU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

716544:WCW RS02035
gene id: 716544:WCW_RS02035
uniprot id: D6YUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

716544:WCW RS06180
gene id: 716544:WCW_RS06180
uniprot id: D6YWX0
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS08495
gene id: 716544:WCW_RS08495
uniprot id: D6YSR3
names: Subunit
messages: Homodimer.

716544:WCW RS02830
gene id: 716544:WCW_RS02830
uniprot id: D6YUZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

716544:WCW RS05620
gene id: 716544:WCW_RS05620
uniprot id: D6YWL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

716544:WCW RS01090
gene id: 716544:WCW_RS01090
uniprot id: D6YTZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

716544:WCW RS01475
gene id: 716544:WCW_RS01475
uniprot id: D6YU71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

716544:WCW RS03100
gene id: 716544:WCW_RS03100
uniprot id: D6YV54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

716544:WCW RS05690
gene id: 716544:WCW_RS05690
uniprot id: D6YWM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

716544:WCW RS03485
gene id: 716544:WCW_RS03485
uniprot id: D6YVC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS08090
gene id: 716544:WCW_RS08090
uniprot id: D6YSI0
names: Similarity
messages: Belongs to the RecJ family.

716544:WCW RS05545
gene id: 716544:WCW_RS05545
uniprot id: D6YWJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS08045
gene id: 716544:WCW_RS08045
uniprot id: D6YSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

716544:WCW RS00310
gene id: 716544:WCW_RS00310
uniprot id: D6YTI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

716544:WCW RS07670
gene id: 716544:WCW_RS07670
uniprot id: D6YS93
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

716544:WCW RS06725
gene id: 716544:WCW_RS06725
uniprot id: D6YRP7
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03310
gene id: 716544:WCW_RS03310
uniprot id: D6YV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

716544:WCW RS07635
gene id: 716544:WCW_RS07635
uniprot id: D6YS88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

716544:WCW RS08085
gene id: 716544:WCW_RS08085
uniprot id: D6YSH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

716544:WCW RS04085
gene id: 716544:WCW_RS04085
uniprot id: D6YVQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS08565
gene id: 716544:WCW_RS08565
uniprot id: D6YSS5
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS00405
gene id: 716544:WCW_RS00405
uniprot id: D6YTK2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

716544:WCW RS06965
gene id: 716544:WCW_RS06965
uniprot id: D6YRU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

716544:WCW RS03850
gene id: 716544:WCW_RS03850
uniprot id: D6YVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

716544:WCW RS08935
gene id: 716544:WCW_RS08935
uniprot id: D6YT03
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

716544:WCW RS07880
gene id: 716544:WCW_RS07880
uniprot id: D6YSD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

716544:WCW RS01620
gene id: 716544:WCW_RS01620
uniprot id: D6YUA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06680
gene id: 716544:WCW_RS06680
uniprot id: D6YRN8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS07115
gene id: 716544:WCW_RS07115
uniprot id: D6YRY0
names: Similarity
messages: Belongs to the PrpD family.

716544:WCW RS00735
gene id: 716544:WCW_RS00735
uniprot id: D6YTR8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS02335
gene id: 716544:WCW_RS02335
uniprot id: D6YUP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

716544:WCW RS08120
gene id: 716544:WCW_RS08120
uniprot id: D6YSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

716544:WCW RS07150
gene id: 716544:WCW_RS07150
uniprot id: D6YRY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

716544:WCW RS00545
gene id: 716544:WCW_RS00545
uniprot id: D6YTN0
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS09300
gene id: 716544:WCW_RS09300
uniprot id: D6YT76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

716544:WCW RS05845
gene id: 716544:WCW_RS05845
uniprot id: D6YWQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

716544:WCW RS03040
gene id: 716544:WCW_RS03040
uniprot id: D6YTB8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS00905
gene id: 716544:WCW_RS00905
uniprot id: D6YTV3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

716544:WCW RS03465
gene id: 716544:WCW_RS03465
uniprot id: D6YVC4
names: Similarity
messages: Belongs to the malate synthase family.

716544:WCW RS04070
gene id: 716544:WCW_RS04070
uniprot id: D6YVP7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

716544:WCW RS08180
gene id: 716544:WCW_RS08180
uniprot id: D6YSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

716544:WCW RS04910
gene id: 716544:WCW_RS04910
uniprot id: D6YW62
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

716544:WCW RS02665
gene id: 716544:WCW_RS02665
uniprot id: D6YUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

716544:WCW RS02105
gene id: 716544:WCW_RS02105
uniprot id: D6YUJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

716544:WCW RS08115
gene id: 716544:WCW_RS08115
uniprot id: D6YSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

716544:WCW RS02095
gene id: 716544:WCW_RS02095
uniprot id: D6YUJ6
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03500
gene id: 716544:WCW_RS03500
uniprot id: D6YVD1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

716544:WCW RS05450
gene id: 716544:WCW_RS05450
uniprot id: D6YWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

716544:WCW RS00830
gene id: 716544:WCW_RS00830
uniprot id: D6YTT7
names: Similarity
messages: Belongs to the sigma-54 factor family.

716544:WCW RS01045
gene id: 716544:WCW_RS01045
uniprot id: D6YTY1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00355
gene id: 716544:WCW_RS00355
uniprot id: D6YTJ2
names: Similarity
messages: Belongs to the MreC family.

716544:WCW RS03790
gene id: 716544:WCW_RS03790
uniprot id: D6YVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

716544:WCW RS01145
gene id: 716544:WCW_RS01145
uniprot id: D6YU04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS01465
gene id: 716544:WCW_RS01465
uniprot id: D6YU69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

716544:WCW RS04595
gene id: 716544:WCW_RS04595
uniprot id: D6YVZ9
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS09335
gene id: 716544:WCW_RS09335
uniprot id: D6YT81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

716544:WCW RS04985
gene id: 716544:WCW_RS04985
uniprot id: D6YW76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

716544:WCW RS06700
gene id: 716544:WCW_RS06700
uniprot id: D6YRP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05265
gene id: 716544:WCW_RS05265
uniprot id: D6YWD3
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS08845
gene id: 716544:WCW_RS08845
uniprot id: D6YSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

716544:WCW RS02540
gene id: 716544:WCW_RS02540
uniprot id: D6YUU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

716544:WCW RS02070
gene id: 716544:WCW_RS02070
uniprot id: D6YUJ1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

716544:WCW RS04380
gene id: 716544:WCW_RS04380
uniprot id: D6YVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

716544:WCW RS01420
gene id: 716544:WCW_RS01420
uniprot id: D6YU60
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

716544:WCW RS02905
gene id: 716544:WCW_RS02905
uniprot id: D6YV14
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

716544:WCW RS03345
gene id: 716544:WCW_RS03345
uniprot id: D6YVA0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

716544:WCW RS08540
gene id: 716544:WCW_RS08540
uniprot id: D6YSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

716544:WCW RS07110
gene id: 716544:WCW_RS07110
uniprot id: D6YRX9
names: Similarity
messages: Belongs to the citrate synthase family.

716544:WCW RS07515
gene id: 716544:WCW_RS07515
uniprot id: D6YS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

716544:WCW RS02970
gene id: 716544:WCW_RS02970
uniprot id: D6YV27
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

716544:WCW RS05445
gene id: 716544:WCW_RS05445
uniprot id: D6YWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

716544:WCW RS05250
gene id: 716544:WCW_RS05250
uniprot id: D6YWD0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

716544:WCW RS04485
gene id: 716544:WCW_RS04485
uniprot id: D6YVX5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

716544:WCW RS07175
gene id: 716544:WCW_RS07175
uniprot id: D6YRZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

716544:WCW RS07025
gene id: 716544:WCW_RS07025
uniprot id: D6YRW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS04715
gene id: 716544:WCW_RS04715
uniprot id: D6YW22
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

716544:WCW RS05435
gene id: 716544:WCW_RS05435
uniprot id: D6YWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

716544:WCW RS08725
gene id: 716544:WCW_RS08725
uniprot id: D6YSW0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

716544:WCW RS07370
gene id: 716544:WCW_RS07370
uniprot id: D6YS31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS07895
gene id: 716544:WCW_RS07895
uniprot id: D6YSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

716544:WCW RS08455
gene id: 716544:WCW_RS08455
uniprot id: D6YSQ4
names: Similarity
messages: Belongs to the peptidase S16 family.

716544:WCW RS06640
gene id: 716544:WCW_RS06640
uniprot id: D6YRN0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

716544:WCW RS05065
gene id: 716544:WCW_RS05065
uniprot id: D6YW95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

716544:WCW RS05995
gene id: 716544:WCW_RS05995
uniprot id: D6YWT7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

716544:WCW RS00005
gene id: 716544:WCW_RS00005
uniprot id: D6YTB8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS01370
gene id: 716544:WCW_RS01370
uniprot id: D6YU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

716544:WCW RS00915
gene id: 716544:WCW_RS00915
uniprot id: D6YTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS08105
gene id: 716544:WCW_RS08105
uniprot id: D6YSI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

716544:WCW RS03365
gene id: 716544:WCW_RS03365
uniprot id: D6YVA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

716544:WCW RS00445
gene id: 716544:WCW_RS00445
uniprot id: D6YTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

716544:WCW RS05605
gene id: 716544:WCW_RS05605
uniprot id: D6YWK8
names: Subunit
messages: Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).

716544:WCW RS08905
gene id: 716544:WCW_RS08905
uniprot id: D6YSZ8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS01890
gene id: 716544:WCW_RS01890
uniprot id: D6YUF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS03315
gene id: 716544:WCW_RS03315
uniprot id: D6YV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

716544:WCW RS03825
gene id: 716544:WCW_RS03825
uniprot id: D6YVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

716544:WCW RS05355
gene id: 716544:WCW_RS05355
uniprot id: D6YWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

716544:WCW RS06715
gene id: 716544:WCW_RS06715
uniprot id: D6YRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

716544:WCW RS00420
gene id: 716544:WCW_RS00420
uniprot id: D6YTK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

716544:WCW RS01635
gene id: 716544:WCW_RS01635
uniprot id: D6YUA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

716544:WCW RS05695
gene id: 716544:WCW_RS05695
uniprot id: D6YWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

716544:WCW RS03565
gene id: 716544:WCW_RS03565
uniprot id: D6YVE5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

716544:WCW RS06290
gene id: 716544:WCW_RS06290
uniprot id: D6YWZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

716544:WCW RS08095
gene id: 716544:WCW_RS08095
uniprot id: D6YSI2
names: Similarity
messages: Belongs to the EUO family.

716544:WCW RS09635
gene id: 716544:WCW_RS09635
uniprot id: D6YTW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00085
gene id: 716544:WCW_RS00085
uniprot id: D6YTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

716544:WCW RS06825
gene id: 716544:WCW_RS06825
uniprot id: D6YRS0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

716544:WCW RS04665
gene id: 716544:WCW_RS04665
uniprot id: D6YW12
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

716544:WCW RS00100
gene id: 716544:WCW_RS00100
uniprot id: D6YTE0
names: Similarity
messages: Belongs to the ParA family.

716544:WCW RS02150
gene id: 716544:WCW_RS02150
uniprot id: D6YUK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

716544:WCW RS01665
gene id: 716544:WCW_RS01665
uniprot id: D6YUA9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

716544:WCW RS07030
gene id: 716544:WCW_RS07030
uniprot id: D6YRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

716544:WCW RS07430
gene id: 716544:WCW_RS07430
uniprot id: D6YS46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

716544:WCW RS04150
gene id: 716544:WCW_RS04150
uniprot id: D6YVR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

716544:WCW RS01505
gene id: 716544:WCW_RS01505
uniprot id: D6YU78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS08100
gene id: 716544:WCW_RS08100
uniprot id: D6YSI3
names: Similarity
messages: Belongs to the peptidase S41A family.

716544:WCW RS05320
gene id: 716544:WCW_RS05320
uniprot id: D6YWE8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS09365
gene id: 716544:WCW_RS09365
uniprot id: D6YT87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

716544:WCW RS07980
gene id: 716544:WCW_RS07980
uniprot id: D6YSF4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

716544:WCW RS05500
gene id: 716544:WCW_RS05500
uniprot id: D6YWI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

716544:WCW RS05835
gene id: 716544:WCW_RS05835
uniprot id: D6YWQ5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

716544:WCW RS07055
gene id: 716544:WCW_RS07055
uniprot id: D6YRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

716544:WCW RS09030
gene id: 716544:WCW_RS09030
uniprot id: D6YT24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

716544:WCW RS07545
gene id: 716544:WCW_RS07545
uniprot id: D6YS69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS06635
gene id: 716544:WCW_RS06635
uniprot id: D6YRM9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

716544:WCW RS08780
gene id: 716544:WCW_RS08780
uniprot id: D6YSX2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

716544:WCW RS05565
gene id: 716544:WCW_RS05565
uniprot id: D6YWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

716544:WCW RS07225
gene id: 716544:WCW_RS07225
uniprot id: D6YS02
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

716544:WCW RS07240
gene id: 716544:WCW_RS07240
uniprot id: D6YS05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

716544:WCW RS07135
gene id: 716544:WCW_RS07135
uniprot id: D6YRY4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

716544:WCW RS05430
gene id: 716544:WCW_RS05430
uniprot id: D6YWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

716544:WCW RS06470
gene id: 716544:WCW_RS06470
uniprot id: D6YRJ3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

716544:WCW RS01720
gene id: 716544:WCW_RS01720
uniprot id: D6YUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

716544:WCW RS08470
gene id: 716544:WCW_RS08470
uniprot id: D6YSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

716544:WCW RS02040
gene id: 716544:WCW_RS02040
uniprot id: D6YUI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

716544:WCW RS07385
gene id: 716544:WCW_RS07385
uniprot id: D6YS35
names: Similarity
messages: Belongs to the thioredoxin family.

716544:WCW RS01905
gene id: 716544:WCW_RS01905
uniprot id: D6YUF8
names: Subcellular Location Annotation
messages: Mitochondrion

716544:WCW RS03870
gene id: 716544:WCW_RS03870
uniprot id: D6YVK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

716544:WCW RS07665
gene id: 716544:WCW_RS07665
uniprot id: D6YS92
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

716544:WCW RS05705
gene id: 716544:WCW_RS05705
uniprot id: D6YWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

716544:WCW RS06460
gene id: 716544:WCW_RS06460
uniprot id: D6YRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS05635
gene id: 716544:WCW_RS05635
uniprot id: D6YWL4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

716544:WCW RS06905
gene id: 716544:WCW_RS06905
uniprot id: D6YRT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

716544:WCW RS07555
gene id: 716544:WCW_RS07555
uniprot id: D6YS71
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS04835
gene id: 716544:WCW_RS04835
uniprot id: D6YW47
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

716544:WCW RS05645
gene id: 716544:WCW_RS05645
uniprot id: D6YWL6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

716544:WCW RS07925
gene id: 716544:WCW_RS07925
uniprot id: D6YSE3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

716544:WCW RS06880
gene id: 716544:WCW_RS06880
uniprot id: D6YRT2
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

716544:WCW RS02945
gene id: 716544:WCW_RS02945
uniprot id: D6YV22
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

716544:WCW RS03585
gene id: 716544:WCW_RS03585
uniprot id: D6YVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

716544:WCW RS01390
gene id: 716544:WCW_RS01390
uniprot id: D6YU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

716544:WCW RS03300
gene id: 716544:WCW_RS03300
uniprot id: D6YV91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

716544:WCW RS08865
gene id: 716544:WCW_RS08865
uniprot id: D6YSZ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

716544:WCW RS09015
gene id: 716544:WCW_RS09015
uniprot id: D6YT21
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

716544:WCW RS03355
gene id: 716544:WCW_RS03355
uniprot id: D6YVA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

716544:WCW RS05375
gene id: 716544:WCW_RS05375
uniprot id: D6YWF9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS04795
gene id: 716544:WCW_RS04795
uniprot id: D6YW39
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS00720
gene id: 716544:WCW_RS00720
uniprot id: D6YTR5
names: Similarity
messages: Belongs to the peptidase M29 family.

716544:WCW RS05755
gene id: 716544:WCW_RS05755
uniprot id: D6YWN8
names: Similarity
messages: Belongs to the Skp family.

716544:WCW RS06685
gene id: 716544:WCW_RS06685
uniprot id: D6YRN9
names: Similarity
messages: Belongs to the CutA family.

716544:WCW RS02635
gene id: 716544:WCW_RS02635
uniprot id: D6YUV9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS00400
gene id: 716544:WCW_RS00400
uniprot id: D6YTK1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

716544:WCW RS01120
gene id: 716544:WCW_RS01120
uniprot id: D6YTZ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

716544:WCW RS09830
gene id: 716544:WCW_RS09830
uniprot id: D6YTB5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

716544:WCW RS08195
gene id: 716544:WCW_RS08195
uniprot id: D6YSK3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

716544:WCW RS10145
gene id: 716544:WCW_RS10145
uniprot id: D6YW53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

716544:WCW RS00780
gene id: 716544:WCW_RS00780
uniprot id: D6YTS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

716544:WCW RS00375
gene id: 716544:WCW_RS00375
uniprot id: D6YTJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

716544:WCW RS03730
gene id: 716544:WCW_RS03730
uniprot id: D6YVI0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

716544:WCW RS04710
gene id: 716544:WCW_RS04710
uniprot id: D6YW21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

716544:WCW RS02020
gene id: 716544:WCW_RS02020
uniprot id: D6YUI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

716544:WCW RS01915
gene id: 716544:WCW_RS01915
uniprot id: D6YUF9
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

716544:WCW RS05345
gene id: 716544:WCW_RS05345
uniprot id: D6YWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

716544:WCW RS02680
gene id: 716544:WCW_RS02680
uniprot id: D6YUX0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

716544:WCW RS00430
gene id: 716544:WCW_RS00430
uniprot id: D6YTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

716544:WCW RS03555
gene id: 716544:WCW_RS03555
uniprot id: D6YVE3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

716544:WCW RS06960
gene id: 716544:WCW_RS06960
uniprot id: D6YRU8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03715
gene id: 716544:WCW_RS03715
uniprot id: D6YVH8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

716544:WCW RS07500
gene id: 716544:WCW_RS07500
uniprot id: D6YS60
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

716544:WCW RS03350
gene id: 716544:WCW_RS03350
uniprot id: D6YVA1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

716544:WCW RS06495
gene id: 716544:WCW_RS06495
uniprot id: D6YRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

716544:WCW RS01360
gene id: 716544:WCW_RS01360
uniprot id: D6YU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

716544:WCW RS05905
gene id: 716544:WCW_RS05905
uniprot id: D6YWR9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

716544:WCW RS08325
gene id: 716544:WCW_RS08325
uniprot id: D6YSM6
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

716544:WCW RS08750
gene id: 716544:WCW_RS08750
uniprot id: D6YSW6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

716544:WCW RS03325
gene id: 716544:WCW_RS03325
uniprot id: D6YV96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

716544:WCW RS05125
gene id: 716544:WCW_RS05125
uniprot id: D6YWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

716544:WCW RS06490
gene id: 716544:WCW_RS06490
uniprot id: D6YRJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

716544:WCW RS05640
gene id: 716544:WCW_RS05640
uniprot id: D6YWL5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

716544:WCW RS01495
gene id: 716544:WCW_RS01495
uniprot id: D6YU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

716544:WCW RS02330
gene id: 716544:WCW_RS02330
uniprot id: D6YUP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

716544:WCW RS02385
gene id: 716544:WCW_RS02385
uniprot id: D6YUQ6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

716544:WCW RS05535
gene id: 716544:WCW_RS05535
uniprot id: D6YWJ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

716544:WCW RS08575
gene id: 716544:WCW_RS08575
uniprot id: D6YSS7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

716544:WCW RS05425
gene id: 716544:WCW_RS05425
uniprot id: D6YWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

716544:WCW RS06910
gene id: 716544:WCW_RS06910
uniprot id: D6YRT7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

716544:WCW RS00960
gene id: 716544:WCW_RS00960
uniprot id: D6YTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

716544:WCW RS07850
gene id: 716544:WCW_RS07850
uniprot id: D6YSC8
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

716544:WCW RS02800
gene id: 716544:WCW_RS02800
uniprot id: D6YUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

716544:WCW RS00730
gene id: 716544:WCW_RS00730
uniprot id: D6YTR7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

716544:WCW RS02320
gene id: 716544:WCW_RS02320
uniprot id: D6YUP3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS02220
gene id: 716544:WCW_RS02220
uniprot id: D6YUM3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS08600
gene id: 716544:WCW_RS08600
uniprot id: D6YST2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

716544:WCW RS09190
gene id: 716544:WCW_RS09190
uniprot id: D6YT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

716544:WCW RS07165
gene id: 716544:WCW_RS07165
uniprot id: D6YRZ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

716544:WCW RS00910
gene id: 716544:WCW_RS00910
uniprot id: D6YTV4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

716544:WCW RS06705
gene id: 716544:WCW_RS06705
uniprot id: D6YRP3
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS04460
gene id: 716544:WCW_RS04460
uniprot id: D6YVX0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

716544:WCW RS07965
gene id: 716544:WCW_RS07965
uniprot id: D6YSF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

716544:WCW RS07375
gene id: 716544:WCW_RS07375
uniprot id: D6YS33
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

716544:WCW RS07160
gene id: 716544:WCW_RS07160
uniprot id: D6YRY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

716544:WCW RS07365
gene id: 716544:WCW_RS07365
uniprot id: D6YS30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS05730
gene id: 716544:WCW_RS05730
uniprot id: D6YWN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

716544:WCW RS00280
gene id: 716544:WCW_RS00280
uniprot id: D6YTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

716544:WCW RS05735
gene id: 716544:WCW_RS05735
uniprot id: D6YWN4
names: Similarity
messages: Belongs to the fabD family.

716544:WCW RS04980
gene id: 716544:WCW_RS04980
uniprot id: D6YW75
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06995
gene id: 716544:WCW_RS06995
uniprot id: D6YRV5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

716544:WCW RS08585
gene id: 716544:WCW_RS08585
uniprot id: D6YSS9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06360
gene id: 716544:WCW_RS06360
uniprot id: D6YX05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

716544:WCW RS03765
gene id: 716544:WCW_RS03765
uniprot id: D6YVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

716544:WCW RS07000
gene id: 716544:WCW_RS07000
uniprot id: D6YRV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06160
gene id: 716544:WCW_RS06160
uniprot id: D6YWW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

716544:WCW RS00325
gene id: 716544:WCW_RS00325
uniprot id: D6YTI6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

716544:WCW RS01030
gene id: 716544:WCW_RS01030
uniprot id: D6YTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

716544:WCW RS04480
gene id: 716544:WCW_RS04480
uniprot id: D6YVX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

716544:WCW RS04350
gene id: 716544:WCW_RS04350
uniprot id: D6YVU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

716544:WCW RS02565
gene id: 716544:WCW_RS02565
uniprot id: D6YUU5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

716544:WCW RS03090
gene id: 716544:WCW_RS03090
uniprot id: D6YV52
names: Similarity
messages: Belongs to the RutC family.

716544:WCW RS03145
gene id: 716544:WCW_RS03145
uniprot id: D6YV63
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS08175
gene id: 716544:WCW_RS08175
uniprot id: D6YSJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS08945
gene id: 716544:WCW_RS08945
uniprot id: D6YT05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

716544:WCW RS08590
gene id: 716544:WCW_RS08590
uniprot id: D6YST0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS03295
gene id: 716544:WCW_RS03295
uniprot id: D6YV90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

716544:WCW RS05110
gene id: 716544:WCW_RS05110
uniprot id: D6YWA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

716544:WCW RS07045
gene id: 716544:WCW_RS07045
uniprot id: D6YRW5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

716544:WCW RS01825
gene id: 716544:WCW_RS01825
uniprot id: D6YUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

716544:WCW RS07530
gene id: 716544:WCW_RS07530
uniprot id: D6YS66
names: Similarity
messages: Belongs to the polysaccharide synthase family.

716544:WCW RS01035
gene id: 716544:WCW_RS01035
uniprot id: D6YTX9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

716544:WCW RS03875
gene id: 716544:WCW_RS03875
uniprot id: D6YVL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

716544:WCW RS00435
gene id: 716544:WCW_RS00435
uniprot id: D6YTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

716544:WCW RS07890
gene id: 716544:WCW_RS07890
uniprot id: D6YSD6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

716544:WCW RS04205
gene id: 716544:WCW_RS04205
uniprot id: D6YVS4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

716544:WCW RS03940
gene id: 716544:WCW_RS03940
uniprot id: D6YVM2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

716544:WCW RS08250
gene id: 716544:WCW_RS08250
uniprot id: D6YSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

716544:WCW RS05595
gene id: 716544:WCW_RS05595
uniprot id: D6YWK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

716544:WCW RS07180
gene id: 716544:WCW_RS07180
uniprot id: D6YRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

716544:WCW RS04525
gene id: 716544:WCW_RS04525
uniprot id: D6YVY5
names: Similarity
messages: Belongs to the asparagine synthetase family.

716544:WCW RS05440
gene id: 716544:WCW_RS05440
uniprot id: D6YWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

716544:WCW RS03140
gene id: 716544:WCW_RS03140
uniprot id: D6YV62
names: Similarity
messages: Belongs to the catalase family.

716544:WCW RS08060
gene id: 716544:WCW_RS08060
uniprot id: D6YSH2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

716544:WCW RS02845
gene id: 716544:WCW_RS02845
uniprot id: D6YV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

716544:WCW RS00815
gene id: 716544:WCW_RS00815
uniprot id: D6YTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS03545
gene id: 716544:WCW_RS03545
uniprot id: D6YVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

716544:WCW RS05480
gene id: 716544:WCW_RS05480
uniprot id: D6YWI0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

716544:WCW RS04255
gene id: 716544:WCW_RS04255
uniprot id: D6YVT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

716544:WCW RS06750
gene id: 716544:WCW_RS06750
uniprot id: D6YRQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

716544:WCW RS07200
gene id: 716544:WCW_RS07200
uniprot id: D6YRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

716544:WCW RS03880
gene id: 716544:WCW_RS03880
uniprot id: D6YVL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

716544:WCW RS02730
gene id: 716544:WCW_RS02730
uniprot id: D6YUY1
names: Similarity
messages: Belongs to the MYG1 family.

716544:WCW RS07210
gene id: 716544:WCW_RS07210
uniprot id: D6YRZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

716544:WCW RS06500
gene id: 716544:WCW_RS06500
uniprot id: D6YRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

716544:WCW RS07985
gene id: 716544:WCW_RS07985
uniprot id: D6YSF5
names: Similarity
messages: Belongs to the PurH family.

716544:WCW RS06760
gene id: 716544:WCW_RS06760
uniprot id: D6YRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

716544:WCW RS04165
gene id: 716544:WCW_RS04165
uniprot id: D6YVR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

716544:WCW RS05925
gene id: 716544:WCW_RS05925
uniprot id: D6YWS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

716544:WCW RS04760
gene id: 716544:WCW_RS04760
uniprot id: D6YW32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

716544:WCW RS04510
gene id: 716544:WCW_RS04510
uniprot id: D6YVY2
names: Similarity
messages: Belongs to the Dps family.

716544:WCW RS08185
gene id: 716544:WCW_RS08185
uniprot id: D6YSK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

716544:WCW RS01550
gene id: 716544:WCW_RS01550
uniprot id: D6YU86
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

716544:WCW RS01275
gene id: 716544:WCW_RS01275
uniprot id: D6YU32
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03645
gene id: 716544:WCW_RS03645
uniprot id: D6YVG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS04840
gene id: 716544:WCW_RS04840
uniprot id: D6YW48
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

716544:WCW RS02255
gene id: 716544:WCW_RS02255
uniprot id: D6YUN0
names: Similarity
messages: Belongs to the arginase family.

716544:WCW RS05725
gene id: 716544:WCW_RS05725
uniprot id: D6YWN2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

716544:WCW RS06575
gene id: 716544:WCW_RS06575
uniprot id: D6YRL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS04905
gene id: 716544:WCW_RS04905
uniprot id: D6YW60
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00505
gene id: 716544:WCW_RS00505
uniprot id: D6YTM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

716544:WCW RS01545
gene id: 716544:WCW_RS01545
uniprot id: D6YU85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00665
gene id: 716544:WCW_RS00665
uniprot id: D6YTQ4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

716544:WCW RS01180
gene id: 716544:WCW_RS01180
uniprot id: D6YU12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

716544:WCW RS06860
gene id: 716544:WCW_RS06860
uniprot id: D6YRS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

716544:WCW RS09145
gene id: 716544:WCW_RS09145
uniprot id: D6YSI8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS07900
gene id: 716544:WCW_RS07900
uniprot id: D6YSD8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

716544:WCW RS06925
gene id: 716544:WCW_RS06925
uniprot id: D6YRU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

716544:WCW RS03580
gene id: 716544:WCW_RS03580
uniprot id: D6YVE8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

716544:WCW RS00465
gene id: 716544:WCW_RS00465
uniprot id: D6YTL4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

716544:WCW RS08130
gene id: 716544:WCW_RS08130
uniprot id: D6YSI9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

716544:WCW RS04145
gene id: 716544:WCW_RS04145
uniprot id: D6YVR1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

716544:WCW RS01425
gene id: 716544:WCW_RS01425
uniprot id: D6YU61
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

716544:WCW RS09710
gene id: 716544:WCW_RS09710
uniprot id: D6YW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

716544:WCW RS02910
gene id: 716544:WCW_RS02910
uniprot id: D6YV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

716544:WCW RS04610
gene id: 716544:WCW_RS04610
uniprot id: D6YW02
names: Similarity
messages: Belongs to the Nudix hydrolase family.

716544:WCW RS05960
gene id: 716544:WCW_RS05960
uniprot id: D6YWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

716544:WCW RS07185
gene id: 716544:WCW_RS07185
uniprot id: D6YRZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

716544:WCW RS08215
gene id: 716544:WCW_RS08215
uniprot id: D6YSK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS07960
gene id: 716544:WCW_RS07960
uniprot id: D6YSF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

716544:WCW RS08730
gene id: 716544:WCW_RS08730
uniprot id: D6YSW1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

716544:WCW RS07035
gene id: 716544:WCW_RS07035
uniprot id: D6YRW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS02380
gene id: 716544:WCW_RS02380
uniprot id: D6YUQ5
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS06790
gene id: 716544:WCW_RS06790
uniprot id: D6YRR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

716544:WCW RS02850
gene id: 716544:WCW_RS02850
uniprot id: D6YV03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

716544:WCW RS06100
gene id: 716544:WCW_RS06100
uniprot id: D6YWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

716544:WCW RS03620
gene id: 716544:WCW_RS03620
uniprot id: D6YVF8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

716544:WCW RS01730
gene id: 716544:WCW_RS01730
uniprot id: D6YUC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

716544:WCW RS01140
gene id: 716544:WCW_RS01140
uniprot id: D6YU03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

716544:WCW RS06745
gene id: 716544:WCW_RS06745
uniprot id: D6YRQ0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

716544:WCW RS02365
gene id: 716544:WCW_RS02365
uniprot id: D6YUQ2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

716544:WCW RS01795
gene id: 716544:WCW_RS01795
uniprot id: D6YUD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS02570
gene id: 716544:WCW_RS02570
uniprot id: D6YUU6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

716544:WCW RS01700
gene id: 716544:WCW_RS01700
uniprot id: D6YUB6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS02300
gene id: 716544:WCW_RS02300
uniprot id: D6YUN9
names: Subcellular Location Annotation
messages: Cytoplasm

716544:WCW RS08415
gene id: 716544:WCW_RS08415
uniprot id: D6YSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

716544:WCW RS07705
gene id: 716544:WCW_RS07705
uniprot id: D6YS99
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

716544:WCW RS04535
gene id: 716544:WCW_RS04535
uniprot id: D6YVY7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

716544:WCW RS07790
gene id: 716544:WCW_RS07790
uniprot id: D6YSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

716544:WCW RS00600
gene id: 716544:WCW_RS00600
uniprot id: D6YTP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

716544:WCW RS03515
gene id: 716544:WCW_RS03515
uniprot id: D6YVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

716544:WCW RS02250
gene id: 716544:WCW_RS02250
uniprot id: D6YUM9
names: Caution
names: Cofactor
names: Domain
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06315
gene id: 716544:WCW_RS06315
uniprot id: D6YWZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05955
gene id: 716544:WCW_RS05955
uniprot id: D6YWS9
names: Similarity
messages: Belongs to the UPF0758 family.

716544:WCW RS04005
gene id: 716544:WCW_RS04005
uniprot id: D6YVN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

716544:WCW RS02115
gene id: 716544:WCW_RS02115
uniprot id: D6YUK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS06670
gene id: 716544:WCW_RS06670
uniprot id: D6YRN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

716544:WCW RS04345
gene id: 716544:WCW_RS04345
uniprot id: D6YVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

716544:WCW RS03680
gene id: 716544:WCW_RS03680
uniprot id: D6YVH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

716544:WCW RS07145
gene id: 716544:WCW_RS07145
uniprot id: D6YRY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

716544:WCW RS01115
gene id: 716544:WCW_RS01115
uniprot id: D6YTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

716544:WCW RS03900
gene id: 716544:WCW_RS03900
uniprot id: D6YVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

716544:WCW RS02900
gene id: 716544:WCW_RS02900
uniprot id: D6YV13
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

716544:WCW RS03910
gene id: 716544:WCW_RS03910
uniprot id: D6YVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

716544:WCW RS05920
gene id: 716544:WCW_RS05920
uniprot id: D6YWS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS02775
gene id: 716544:WCW_RS02775
uniprot id: D6YUZ0
names: Similarity
messages: Belongs to the SufE family.

716544:WCW RS07675
gene id: 716544:WCW_RS07675
uniprot id: D6YS94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS00165
gene id: 716544:WCW_RS00165
uniprot id: D6YTF4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

716544:WCW RS08755
gene id: 716544:WCW_RS08755
uniprot id: D6YSW7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

716544:WCW RS02585
gene id: 716544:WCW_RS02585
uniprot id: D6YUV0
names: Similarity
messages: Belongs to the UPF0235 family.

716544:WCW RS02815
gene id: 716544:WCW_RS02815
uniprot id: D6YUZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

716544:WCW RS02810
gene id: 716544:WCW_RS02810
uniprot id: D6YUZ5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

716544:WCW RS01135
gene id: 716544:WCW_RS01135
uniprot id: D6YU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

716544:WCW RS04680
gene id: 716544:WCW_RS04680
uniprot id: D6YW15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

716544:WCW RS00795
gene id: 716544:WCW_RS00795
uniprot id: D6YTT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

716544:WCW RS05720
gene id: 716544:WCW_RS05720
uniprot id: D6YWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

716544:WCW RS06720
gene id: 716544:WCW_RS06720
uniprot id: D6YRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

716544:WCW RS04675
gene id: 716544:WCW_RS04675
uniprot id: D6YW14
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS08970
gene id: 716544:WCW_RS08970
uniprot id: D6YT10
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

716544:WCW RS07120
gene id: 716544:WCW_RS07120
uniprot id: D6YRY1
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS06400
gene id: 716544:WCW_RS06400
uniprot id: D6YRH9
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS07905
gene id: 716544:WCW_RS07905
uniprot id: D6YSD9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

716544:WCW RS03420
gene id: 716544:WCW_RS03420
uniprot id: D6YVB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

716544:WCW RS08320
gene id: 716544:WCW_RS08320
uniprot id: D6YSM5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

716544:WCW RS03360
gene id: 716544:WCW_RS03360
uniprot id: D6YVA3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

716544:WCW RS03670
gene id: 716544:WCW_RS03670
uniprot id: D6YVG8
names: Similarity
messages: Belongs to the bacterial glucokinase family.

716544:WCW RS03795
gene id: 716544:WCW_RS03795
uniprot id: D6YVJ3
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

716544:WCW RS07700
gene id: 716544:WCW_RS07700
uniprot id: D6YS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

716544:WCW RS09020
gene id: 716544:WCW_RS09020
uniprot id: D6YT22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

716544:WCW RS04440
gene id: 716544:WCW_RS04440
uniprot id: D6YVW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

716544:WCW RS07215
gene id: 716544:WCW_RS07215
uniprot id: D6YS00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

716544:WCW RS05145
gene id: 716544:WCW_RS05145
uniprot id: D6YWB1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

716544:WCW RS07220
gene id: 716544:WCW_RS07220
uniprot id: D6YS01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

716544:WCW RS04860
gene id: 716544:WCW_RS04860
uniprot id: D6YW52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

716544:WCW RS09320
gene id: 716544:WCW_RS09320
uniprot id: D6YT78
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS03280
gene id: 716544:WCW_RS03280
uniprot id: D6YV87
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS02805
gene id: 716544:WCW_RS02805
uniprot id: D6YUZ4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

716544:WCW RS05035
gene id: 716544:WCW_RS05035
uniprot id: D6YW86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

716544:WCW RS07945
gene id: 716544:WCW_RS07945
uniprot id: D6YSE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS09220
gene id: 716544:WCW_RS09220
uniprot id: D6YT60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

716544:WCW RS00390
gene id: 716544:WCW_RS00390
uniprot id: D6YTJ9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

716544:WCW RS01630
gene id: 716544:WCW_RS01630
uniprot id: D6YUA2
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

716544:WCW RS07395
gene id: 716544:WCW_RS07395
uniprot id: D6YS37
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

716544:WCW RS02780
gene id: 716544:WCW_RS02780
uniprot id: D6YUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

716544:WCW RS07195
gene id: 716544:WCW_RS07195
uniprot id: D6YRZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

716544:WCW RS00460
gene id: 716544:WCW_RS00460
uniprot id: D6YTL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

716544:WCW RS07955
gene id: 716544:WCW_RS07955
uniprot id: D6YSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

716544:WCW RS05505
gene id: 716544:WCW_RS05505
uniprot id: D6YWI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

716544:WCW RS06920
gene id: 716544:WCW_RS06920
uniprot id: D6YRT9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

716544:WCW RS04060
gene id: 716544:WCW_RS04060
uniprot id: D6YVP5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

716544:WCW RS05305
gene id: 716544:WCW_RS05305
uniprot id: D6YWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

716544:WCW RS05880
gene id: 716544:WCW_RS05880
uniprot id: D6YWR4
names: Similarity
messages: Belongs to the asparagine synthetase family.

716544:WCW RS07010
gene id: 716544:WCW_RS07010
uniprot id: D6YRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

716544:WCW RS08595
gene id: 716544:WCW_RS08595
uniprot id: D6YST1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

716544:WCW RS10330
gene id: 716544:WCW_RS10330
uniprot id: D6YSC0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

716544:WCW RS00130
gene id: 716544:WCW_RS00130
uniprot id: D6YTE7
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS06105
gene id: 716544:WCW_RS06105
uniprot id: D6YWV4
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS07445
gene id: 716544:WCW_RS07445
uniprot id: D6YS49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

716544:WCW RS02505
gene id: 716544:WCW_RS02505
uniprot id: D6YUT2
names: Similarity
messages: Belongs to the terpene synthase family.

716544:WCW RS05510
gene id: 716544:WCW_RS05510
uniprot id: D6YWI6
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03930
gene id: 716544:WCW_RS03930
uniprot id: D6YVM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

716544:WCW RS04600
gene id: 716544:WCW_RS04600
uniprot id: D6YW00
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS01995
gene id: 716544:WCW_RS01995
uniprot id: D6YUH6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

716544:WCW RS08125
gene id: 716544:WCW_RS08125
uniprot id: D6YSI8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

716544:WCW RS06335
gene id: 716544:WCW_RS06335
uniprot id: D6YX00
names: Caution
names: Function
names: PTM
names: Similarity
messages: Autophosphorylated on serine and threonine residues.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.

716544:WCW RS03470
gene id: 716544:WCW_RS03470
uniprot id: D6YVC5
names: Cofactor
messages: Can also use Mn(2+) ion.

716544:WCW RS08975
gene id: 716544:WCW_RS08975
uniprot id: D6YT11
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

716544:WCW RS04495
gene id: 716544:WCW_RS04495
uniprot id: D6YVX7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

716544:WCW RS07235
gene id: 716544:WCW_RS07235
uniprot id: D6YS04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

716544:WCW RS02790
gene id: 716544:WCW_RS02790
uniprot id: D6YUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

716544:WCW RS09385
gene id: 716544:WCW_RS09385
uniprot id: D6YT92
names: Similarity
messages: Belongs to the disproportionating enzyme family.

716544:WCW RS02425
gene id: 716544:WCW_RS02425
uniprot id: D6YUR4
names: Similarity
messages: Belongs to the DEAD box helicase family.

716544:WCW RS07860
gene id: 716544:WCW_RS07860
uniprot id: D6YSD0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00340
gene id: 716544:WCW_RS00340
uniprot id: D6YTI9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

716544:WCW RS01280
gene id: 716544:WCW_RS01280
uniprot id: D6YU33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

716544:WCW RS07660
gene id: 716544:WCW_RS07660
uniprot id: D6YS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

716544:WCW RS04890
gene id: 716544:WCW_RS04890
uniprot id: D6YW57
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

716544:WCW RS02175
gene id: 716544:WCW_RS02175
uniprot id: D6YUL1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

716544:WCW RS04435
gene id: 716544:WCW_RS04435
uniprot id: D6YVW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

716544:WCW RS06040
gene id: 716544:WCW_RS06040
uniprot id: D6YWU6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

716544:WCW RS08240
gene id: 716544:WCW_RS08240
uniprot id: D6YSL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

716544:WCW RS08330
gene id: 716544:WCW_RS08330
uniprot id: D6YSM7
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS07730
gene id: 716544:WCW_RS07730
uniprot id: D6YSA4
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

716544:WCW RS00395
gene id: 716544:WCW_RS00395
uniprot id: D6YTK0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

716544:WCW RS02770
gene id: 716544:WCW_RS02770
uniprot id: D6YUY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

716544:WCW RS03655
gene id: 716544:WCW_RS03655
uniprot id: D6YVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

716544:WCW RS03785
gene id: 716544:WCW_RS03785
uniprot id: D6YVJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

716544:WCW RS02545
gene id: 716544:WCW_RS02545
uniprot id: D6YUU1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

716544:WCW RS05575
gene id: 716544:WCW_RS05575
uniprot id: D6YWJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

716544:WCW RS06095
gene id: 716544:WCW_RS06095
uniprot id: D6YWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

716544:WCW RS00260
gene id: 716544:WCW_RS00260
uniprot id: D6YTH2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

716544:WCW RS05665
gene id: 716544:WCW_RS05665
uniprot id: D6YWM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

716544:WCW RS07435
gene id: 716544:WCW_RS07435
uniprot id: D6YS47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

716544:WCW RS09475
gene id: 716544:WCW_RS09475
uniprot id: D6YTB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS04190
gene id: 716544:WCW_RS04190
uniprot id: D6YVS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

716544:WCW RS06395
gene id: 716544:WCW_RS06395
uniprot id: D6YRH8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS04445
gene id: 716544:WCW_RS04445
uniprot id: D6YVW7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

716544:WCW RS03630
gene id: 716544:WCW_RS03630
uniprot id: D6YVG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

716544:WCW RS07155
gene id: 716544:WCW_RS07155
uniprot id: D6YRY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

716544:WCW RS01640
gene id: 716544:WCW_RS01640
uniprot id: D6YUA4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

716544:WCW RS00425
gene id: 716544:WCW_RS00425
uniprot id: D6YTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

716544:WCW RS06815
gene id: 716544:WCW_RS06815
uniprot id: D6YRR7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

716544:WCW RS00585
gene id: 716544:WCW_RS00585
uniprot id: D6YTN8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

716544:WCW RS03950
gene id: 716544:WCW_RS03950
uniprot id: D6YVM4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

716544:WCW RS06390
gene id: 716544:WCW_RS06390
uniprot id: D6YRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

716544:WCW RS03650
gene id: 716544:WCW_RS03650
uniprot id: D6YVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

716544:WCW RS04160
gene id: 716544:WCW_RS04160
uniprot id: D6YVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

716544:WCW RS06740
gene id: 716544:WCW_RS06740
uniprot id: D6YRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

716544:WCW RS02475
gene id: 716544:WCW_RS02475
uniprot id: D6YUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

716544:WCW RS08210
gene id: 716544:WCW_RS08210
uniprot id: D6YSK6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

716544:WCW RS05385
gene id: 716544:WCW_RS05385
uniprot id: D6YWG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

716544:WCW RS01815
gene id: 716544:WCW_RS01815
uniprot id: D6YUD9
names: Similarity
messages: Belongs to the UDPGP type 1 family.

716544:WCW RS07485
gene id: 716544:WCW_RS07485
uniprot id: D6YS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

716544:WCW RS03430
gene id: 716544:WCW_RS03430
uniprot id: D6YVB7
names: Similarity
messages: Belongs to the peptidase M13 family.

716544:WCW RS00065
gene id: 716544:WCW_RS00065
uniprot id: D6YTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

716544:WCW RS05025
gene id: 716544:WCW_RS05025
uniprot id: D6YW84
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

716544:WCW RS05395
gene id: 716544:WCW_RS05395
uniprot id: D6YWG3
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

716544:WCW RS03685
gene id: 716544:WCW_RS03685
uniprot id: D6YVH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

716544:WCW RS05235
gene id: 716544:WCW_RS05235
uniprot id: D6YWC7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

716544:WCW RS07190
gene id: 716544:WCW_RS07190
uniprot id: D6YRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

716544:WCW RS00985
gene id: 716544:WCW_RS00985
uniprot id: D6YTW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS02045
gene id: 716544:WCW_RS02045
uniprot id: D6YUI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

716544:WCW RS09590
gene id: 716544:WCW_RS09590
uniprot id: D6YX27
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

716544:WCW RS05350
gene id: 716544:WCW_RS05350
uniprot id: D6YWF4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS07935
gene id: 716544:WCW_RS07935
uniprot id: D6YSE5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

716544:WCW RS08255
gene id: 716544:WCW_RS08255
uniprot id: D6YSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

716544:WCW RS06415
gene id: 716544:WCW_RS06415
uniprot id: D6YRI2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

716544:WCW RS01510
gene id: 716544:WCW_RS01510
uniprot id: D6YU79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

716544:WCW RS04450
gene id: 716544:WCW_RS04450
uniprot id: D6YVW8
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

716544:WCW RS07285
gene id: 716544:WCW_RS07285
uniprot id: D6YS14
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

716544:WCW RS07840
gene id: 716544:WCW_RS07840
uniprot id: D6YSC6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

716544:WCW RS07535
gene id: 716544:WCW_RS07535
uniprot id: D6YS67
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

716544:WCW RS07280
gene id: 716544:WCW_RS07280
uniprot id: D6YS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

716544:WCW RS03265
gene id: 716544:WCW_RS03265
uniprot id: D6YV84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

716544:WCW RS09445
gene id: 716544:WCW_RS09445
uniprot id: D6YTB0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

716544:WCW RS05825
gene id: 716544:WCW_RS05825
uniprot id: D6YWQ3
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

716544:WCW RS01335
gene id: 716544:WCW_RS01335
uniprot id: D6YU45
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

716544:WCW RS09415
gene id: 716544:WCW_RS09415
uniprot id: D6YTA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

716544:WCW RS07230
gene id: 716544:WCW_RS07230
uniprot id: D6YS03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

716544:WCW RS01285
gene id: 716544:WCW_RS01285
uniprot id: D6YU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

716544:WCW RS07490
gene id: 716544:WCW_RS07490
uniprot id: D6YS58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS03860
gene id: 716544:WCW_RS03860
uniprot id: D6YVK7
names: Similarity
messages: Belongs to the asp23 family.

716544:WCW RS03810
gene id: 716544:WCW_RS03810
uniprot id: D6YVJ6
names: Subcellular Location Annotation
messages: Cytoplasm

716544:WCW RS02895
gene id: 716544:WCW_RS02895
uniprot id: D6YV12
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

716544:WCW RS06200
gene id: 716544:WCW_RS06200
uniprot id: D6YWX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

716544:WCW RS05910
gene id: 716544:WCW_RS05910
uniprot id: D6YWS0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

716544:WCW RS05310
gene id: 716544:WCW_RS05310
uniprot id: D6YWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

716544:WCW RS08770
gene id: 716544:WCW_RS08770
uniprot id: D6YSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

716544:WCW RS01450
gene id: 716544:WCW_RS01450
uniprot id: D6YU66
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS05255
gene id: 716544:WCW_RS05255
uniprot id: D6YWD1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

716544:WCW RS05200
gene id: 716544:WCW_RS05200
uniprot id: D6YWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

716544:WCW RS06370
gene id: 716544:WCW_RS06370
uniprot id: D6YRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

716544:WCW RS04880
gene id: 716544:WCW_RS04880
uniprot id: D6YW55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

716544:WCW RS05550
gene id: 716544:WCW_RS05550
uniprot id: D6YWJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

716544:WCW RS02915
gene id: 716544:WCW_RS02915
uniprot id: D6YV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

716544:WCW RS08625
gene id: 716544:WCW_RS08625
uniprot id: D6YST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

716544:WCW RS02430
gene id: 716544:WCW_RS02430
uniprot id: D6YUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

716544:WCW RS01185
gene id: 716544:WCW_RS01185
uniprot id: D6YU13
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

716544:WCW RS08570
gene id: 716544:WCW_RS08570
uniprot id: D6YSS6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

716544:WCW RS05070
gene id: 716544:WCW_RS05070
uniprot id: D6YW96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS02000
gene id: 716544:WCW_RS02000
uniprot id: D6YUH7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS00335
gene id: 716544:WCW_RS00335
uniprot id: D6YTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

716544:WCW RS00105
gene id: 716544:WCW_RS00105
uniprot id: D6YTE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

716544:WCW RS02555
gene id: 716544:WCW_RS02555
uniprot id: D6YUU3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

716544:WCW RS07140
gene id: 716544:WCW_RS07140
uniprot id: D6YRY5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

716544:WCW RS00695
gene id: 716544:WCW_RS00695
uniprot id: D6YTR0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS03405
gene id: 716544:WCW_RS03405
uniprot id: D6YVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

716544:WCW RS05315
gene id: 716544:WCW_RS05315
uniprot id: D6YWE7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

716544:WCW RS07130
gene id: 716544:WCW_RS07130
uniprot id: D6YRY3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

716544:WCW RS07270
gene id: 716544:WCW_RS07270
uniprot id: D6YS11
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

716544:WCW RS06655
gene id: 716544:WCW_RS06655
uniprot id: D6YRN3
names: Similarity
messages: Belongs to the glutamine synthetase family.

716544:WCW RS04320
gene id: 716544:WCW_RS04320
uniprot id: D6YVU3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

716544:WCW RS04690
gene id: 716544:WCW_RS04690
uniprot id: D6YW17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

716544:WCW RS07565
gene id: 716544:WCW_RS07565
uniprot id: D6YS73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

716544:WCW RS06735
gene id: 716544:WCW_RS06735
uniprot id: D6YRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

716544:WCW RS00660
gene id: 716544:WCW_RS00660
uniprot id: D6YTQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

716544:WCW RS04575
gene id: 716544:WCW_RS04575
uniprot id: D6YVZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

716544:WCW RS08405
gene id: 716544:WCW_RS08405
uniprot id: D6YSP3
names: Similarity
messages: Belongs to the CinA family.

716544:WCW RS01515
gene id: 716544:WCW_RS01515
uniprot id: D6YU80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

716544:WCW RS05805
gene id: 716544:WCW_RS05805
uniprot id: D6YWP9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

716544:WCW RS01175
gene id: 716544:WCW_RS01175
uniprot id: D6YU11
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

716544:WCW RS01320
gene id: 716544:WCW_RS01320
uniprot id: D6YU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

716544:WCW RS02820
gene id: 716544:WCW_RS02820
uniprot id: D6YUZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

716544:WCW RS07875
gene id: 716544:WCW_RS07875
uniprot id: D6YSD3
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS06455
gene id: 716544:WCW_RS06455
uniprot id: D6YRJ0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

716544:WCW RS05010
gene id: 716544:WCW_RS05010
uniprot id: D6YW81
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

716544:WCW RS05815
gene id: 716544:WCW_RS05815
uniprot id: D6YWQ1
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS08335
gene id: 716544:WCW_RS08335
uniprot id: D6YSM8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

716544:WCW RS08425
gene id: 716544:WCW_RS08425
uniprot id: D6YSP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

716544:WCW RS07920
gene id: 716544:WCW_RS07920
uniprot id: D6YSE2
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS08615
gene id: 716544:WCW_RS08615
uniprot id: D6YST5
names: Similarity
messages: Belongs to the UDPGP type 1 family.

716544:WCW RS04140
gene id: 716544:WCW_RS04140
uniprot id: D6YVR0
names: Similarity
messages: Belongs to the ribF family.

716544:WCW RS04300
gene id: 716544:WCW_RS04300
uniprot id: D6YVT9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

716544:WCW RS05795
gene id: 716544:WCW_RS05795
uniprot id: D6YWP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

716544:WCW RS02240
gene id: 716544:WCW_RS02240
uniprot id: D6YUM7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

716544:WCW RS07245
gene id: 716544:WCW_RS07245
uniprot id: D6YS06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

716544:WCW RS06695
gene id: 716544:WCW_RS06695
uniprot id: D6YRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

716544:WCW RS03775
gene id: 716544:WCW_RS03775
uniprot id: D6YVI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

716544:WCW RS06005
gene id: 716544:WCW_RS06005
uniprot id: D6YWT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

716544:WCW RS01130
gene id: 716544:WCW_RS01130
uniprot id: D6YU01
names: Similarity
messages: Belongs to the YjdM family.

716544:WCW RS07355
gene id: 716544:WCW_RS07355
uniprot id: D6YS28
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS03440
gene id: 716544:WCW_RS03440
uniprot id: D6YVB9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

716544:WCW RS05740
gene id: 716544:WCW_RS05740
uniprot id: D6YWN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

716544:WCW RS01685
gene id: 716544:WCW_RS01685
uniprot id: D6YUB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

716544:WCW RS04020
gene id: 716544:WCW_RS04020
uniprot id: D6YVN8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

716544:WCW RS07835
gene id: 716544:WCW_RS07835
uniprot id: D6YSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

716544:WCW RS05870
gene id: 716544:WCW_RS05870
uniprot id: D6YWR2
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS00680
gene id: 716544:WCW_RS00680
uniprot id: D6YTQ7
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS05590
gene id: 716544:WCW_RS05590
uniprot id: D6YWK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

716544:WCW RS08260
gene id: 716544:WCW_RS08260
uniprot id: D6YSL6
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS00920
gene id: 716544:WCW_RS00920
uniprot id: D6YTV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

716544:WCW RS04470
gene id: 716544:WCW_RS04470
uniprot id: D6YVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

716544:WCW RS06570
gene id: 716544:WCW_RS06570
uniprot id: D6YRL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS00190
gene id: 716544:WCW_RS00190
uniprot id: D6YTF9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

716544:WCW RS03935
gene id: 716544:WCW_RS03935
uniprot id: D6YVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

716544:WCW RS05850
gene id: 716544:WCW_RS05850
uniprot id: D6YWQ8
names: Subcellular Location Annotation
messages: Membrane

716544:WCW RS05120
gene id: 716544:WCW_RS05120
uniprot id: D6YWA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05600
gene id: 716544:WCW_RS05600
uniprot id: D6YWK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS01970
gene id: 716544:WCW_RS01970
uniprot id: D6YUH1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

716544:WCW RS01615
gene id: 716544:WCW_RS01615
uniprot id: D6YU99
names: Function
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

716544:WCW RS07100
gene id: 716544:WCW_RS07100
uniprot id: D6YRX7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

716544:WCW RS00345
gene id: 716544:WCW_RS00345
uniprot id: D6YTJ0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

716544:WCW RS05455
gene id: 716544:WCW_RS05455
uniprot id: D6YWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

716544:WCW RS02955
gene id: 716544:WCW_RS02955
uniprot id: D6YV24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

716544:WCW RS02080
gene id: 716544:WCW_RS02080
uniprot id: D6YUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

716544:WCW RS05585
gene id: 716544:WCW_RS05585
uniprot id: D6YWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

716544:WCW RS03885
gene id: 716544:WCW_RS03885
uniprot id: D6YVL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

716544:WCW RS08160
gene id: 716544:WCW_RS08160
uniprot id: D6YSJ6
names: Similarity
messages: Belongs to the Fur family.

716544:WCW RS06310
gene id: 716544:WCW_RS06310
uniprot id: D6YWZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

716544:WCW RS05100
gene id: 716544:WCW_RS05100
uniprot id: D6YWA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

716544:WCW RS05990
gene id: 716544:WCW_RS05990
uniprot id: D6YWT6
names: Similarity
messages: Belongs to the citrate synthase family.

716544:WCW RS01195
gene id: 716544:WCW_RS01195
uniprot id: D6YU15
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

716544:WCW RS06785
gene id: 716544:WCW_RS06785
uniprot id: D6YRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

716544:WCW RS09860
gene id: 716544:WCW_RS09860
uniprot id: D6YTJ3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

716544:WCW RS00410
gene id: 716544:WCW_RS00410
uniprot id: D6YTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

716544:WCW RS07170
gene id: 716544:WCW_RS07170
uniprot id: D6YRZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

716544:WCW RS02350
gene id: 716544:WCW_RS02350
uniprot id: D6YUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane