714067:GXN75 RS03815
gene id: 714067:GXN75_RS03815
uniprot id: A0A1N7NVY8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

714067:GXN75 RS14055
gene id: 714067:GXN75_RS14055
uniprot id: A0A1N7KEL2
names: Similarity
messages: Belongs to the citrate synthase family.

714067:GXN75 RS00910
gene id: 714067:GXN75_RS00910
uniprot id: A0A1N7MW22
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS03830
gene id: 714067:GXN75_RS03830
uniprot id: A0A1N7NWE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01385
gene id: 714067:GXN75_RS01385
uniprot id: A0A1N7N0Z3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS10510
gene id: 714067:GXN75_RS10510
uniprot id: A0A1N7J0Y1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

714067:GXN75 RS07845
gene id: 714067:GXN75_RS07845
uniprot id: A0A1N7IKX3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

714067:GXN75 RS12610
gene id: 714067:GXN75_RS12610
uniprot id: A0A1N7KXT9
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

714067:GXN75 RS03040
gene id: 714067:GXN75_RS03040
uniprot id: A0A1N7PYP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

714067:GXN75 RS14075
gene id: 714067:GXN75_RS14075
uniprot id: A0A1N7KE87
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

714067:GXN75 RS16255
gene id: 714067:GXN75_RS16255
uniprot id: A0A1N7JXT7
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

714067:GXN75 RS17315
gene id: 714067:GXN75_RS17315
uniprot id: A0A1N7JI03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

714067:GXN75 RS13805
gene id: 714067:GXN75_RS13805
uniprot id: A0A1N7KHR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02515
gene id: 714067:GXN75_RS02515
uniprot id: A0A1N7NIF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS01850
gene id: 714067:GXN75_RS01850
uniprot id: A0A1N7P4X8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

714067:GXN75 RS02935
gene id: 714067:GXN75_RS02935
uniprot id: A0A1N7NMS9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

714067:GXN75 RS04580
gene id: 714067:GXN75_RS04580
uniprot id: A0A1N7LI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

714067:GXN75 RS06325
gene id: 714067:GXN75_RS06325
uniprot id: A0A1N7MLW5
names: Similarity
messages: Belongs to the peptidase M56 family.

714067:GXN75 RS04885
gene id: 714067:GXN75_RS04885
uniprot id: A0A1N7LEH1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS13525
gene id: 714067:GXN75_RS13525
uniprot id: A0A1N7KKZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01415
gene id: 714067:GXN75_RS01415
uniprot id: A0A1N7N159
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

714067:GXN75 RS13295
gene id: 714067:GXN75_RS13295
uniprot id: A0A1N7KNW0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS15210
gene id: 714067:GXN75_RS15210
uniprot id: A0A1N7PN18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS04590
gene id: 714067:GXN75_RS04590
uniprot id: A0A1N7LHZ0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

714067:GXN75 RS02735
gene id: 714067:GXN75_RS02735
uniprot id: A0A1N7NKU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

714067:GXN75 RS05420
gene id: 714067:GXN75_RS05420
uniprot id: A0A1N7L866
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16230
gene id: 714067:GXN75_RS16230
uniprot id: A0A1N7JY49
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

714067:GXN75 RS02455
gene id: 714067:GXN75_RS02455
uniprot id: A0A1N7NI69
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

714067:GXN75 RS14975
gene id: 714067:GXN75_RS14975
uniprot id: A0A1N7Q6I6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07075
gene id: 714067:GXN75_RS07075
uniprot id: A0A1N7M1L5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

714067:GXN75 RS06895
gene id: 714067:GXN75_RS06895
uniprot id: A0A1N7LZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

714067:GXN75 RS04815
gene id: 714067:GXN75_RS04815
uniprot id: A0A1N7LF85
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS09780
gene id: 714067:GXN75_RS09780
uniprot id: A0A1N7IWH6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10620
gene id: 714067:GXN75_RS10620
uniprot id: A0A1N7J1H7
names: Similarity
messages: Belongs to the peptidase S16 family.

714067:GXN75 RS06560
gene id: 714067:GXN75_RS06560
uniprot id: A0A1N7LWI2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

714067:GXN75 RS06160
gene id: 714067:GXN75_RS06160
uniprot id: A0A1N7MK15
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

714067:GXN75 RS14925
gene id: 714067:GXN75_RS14925
uniprot id: A0A1N7N6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

714067:GXN75 RS14830
gene id: 714067:GXN75_RS14830
uniprot id: A0A1N7N7Z3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

714067:GXN75 RS03625
gene id: 714067:GXN75_RS03625
uniprot id: A0A1N7NTZ1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

714067:GXN75 RS03095
gene id: 714067:GXN75_RS03095
uniprot id: A0A1N7PZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS12180
gene id: 714067:GXN75_RS12180
uniprot id: A0A1N7PS58
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS02720
gene id: 714067:GXN75_RS02720
uniprot id: A0A1N7NKA0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

714067:GXN75 RS16265
gene id: 714067:GXN75_RS16265
uniprot id: A0A1N7JXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

714067:GXN75 RS17025
gene id: 714067:GXN75_RS17025
uniprot id: A0A1N7JKQ6
names: Similarity
messages: Belongs to the FBPase class 2 family.

714067:GXN75 RS03490
gene id: 714067:GXN75_RS03490
uniprot id: A0A1N7NS18
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS10725
gene id: 714067:GXN75_RS10725
uniprot id: A0A1N7J1T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

714067:GXN75 RS09050
gene id: 714067:GXN75_RS09050
uniprot id: A0A1N7IRY4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

714067:GXN75 RS16850
gene id: 714067:GXN75_RS16850
uniprot id: A0A1N7JN03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

714067:GXN75 RS00655
gene id: 714067:GXN75_RS00655
uniprot id: A0A1N7MTP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16630
gene id: 714067:GXN75_RS16630
uniprot id: A0A1N7JRS2
names: Subcellular Location Annotation
messages: Cytoplasm

714067:GXN75 RS13415
gene id: 714067:GXN75_RS13415
uniprot id: A0A1N7KMC6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

714067:GXN75 RS13315
gene id: 714067:GXN75_RS13315
uniprot id: A0A1N7KNI6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

714067:GXN75 RS03570
gene id: 714067:GXN75_RS03570
uniprot id: A0A1N7NTE7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

714067:GXN75 RS15445
gene id: 714067:GXN75_RS15445
uniprot id: A0A1N7PLF9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

714067:GXN75 RS02930
gene id: 714067:GXN75_RS02930
uniprot id: A0A1N7NMP5
names: Similarity
messages: Belongs to the SCO1/2 family.

714067:GXN75 RS01520
gene id: 714067:GXN75_RS01520
uniprot id: A0A1N7N228
names: Similarity
messages: Belongs to the OsmC/Ohr family.

714067:GXN75 RS10665
gene id: 714067:GXN75_RS10665
uniprot id: A0A1N7J1Q5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

714067:GXN75 RS12665
gene id: 714067:GXN75_RS12665
uniprot id: A0A1N7KWZ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS13250
gene id: 714067:GXN75_RS13250
uniprot id: A0A1N7KPB0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

714067:GXN75 RS04295
gene id: 714067:GXN75_RS04295
uniprot id: A0A1N7LLB7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS17095
gene id: 714067:GXN75_RS17095
uniprot id: A0A1N7JK71
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

714067:GXN75 RS04035
gene id: 714067:GXN75_RS04035
uniprot id: A0A1N7LNT4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

714067:GXN75 RS03845
gene id: 714067:GXN75_RS03845
uniprot id: A0A1N7NWF6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

714067:GXN75 RS16815
gene id: 714067:GXN75_RS16815
uniprot id: A0A1N7JNJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS10610
gene id: 714067:GXN75_RS10610
uniprot id: A0A1N7J1D8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

714067:GXN75 RS01425
gene id: 714067:GXN75_RS01425
uniprot id: A0A1N7N1E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

714067:GXN75 RS12575
gene id: 714067:GXN75_RS12575
uniprot id: A0A1N7KYM1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

714067:GXN75 RS07975
gene id: 714067:GXN75_RS07975
uniprot id: A0A1N7ILI8
names: Similarity
messages: Belongs to the asp23 family.

714067:GXN75 RS06580
gene id: 714067:GXN75_RS06580
uniprot id: A0A1N7LWT0
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS01600
gene id: 714067:GXN75_RS01600
uniprot id: A0A1N7P7P3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

714067:GXN75 RS11000
gene id: 714067:GXN75_RS11000
uniprot id: A0A1N7J3W9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS07990
gene id: 714067:GXN75_RS07990
uniprot id: A0A1N7ILL2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

714067:GXN75 RS04925
gene id: 714067:GXN75_RS04925
uniprot id: A0A1N7LDW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

714067:GXN75 RS14805
gene id: 714067:GXN75_RS14805
uniprot id: A0A1N7N8C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

714067:GXN75 RS08455
gene id: 714067:GXN75_RS08455
uniprot id: A0A1N7IP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

714067:GXN75 RS11230
gene id: 714067:GXN75_RS11230
uniprot id: A0A1N7J524
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

714067:GXN75 RS15240
gene id: 714067:GXN75_RS15240
uniprot id: A0A1N7PMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

714067:GXN75 RS07425
gene id: 714067:GXN75_RS07425
uniprot id: A0A1N7M5H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

714067:GXN75 RS06555
gene id: 714067:GXN75_RS06555
uniprot id: A0A1N7LWG7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

714067:GXN75 RS13015
gene id: 714067:GXN75_RS13015
uniprot id: A0A1N7KSD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

714067:GXN75 RS10440
gene id: 714067:GXN75_RS10440
uniprot id: A0A1N7J0G5
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS09845
gene id: 714067:GXN75_RS09845
uniprot id: A0A1N7IWV4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS09225
gene id: 714067:GXN75_RS09225
uniprot id: A0A1N7IT05
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

714067:GXN75 RS00780
gene id: 714067:GXN75_RS00780
uniprot id: A0A1N7MUD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS14350
gene id: 714067:GXN75_RS14350
uniprot id: A0A1N7NCN1
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS15510
gene id: 714067:GXN75_RS15510
uniprot id: A0A1N7PKA6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

714067:GXN75 RS16625
gene id: 714067:GXN75_RS16625
uniprot id: A0A1N7JRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

714067:GXN75 RS06815
gene id: 714067:GXN75_RS06815
uniprot id: A0A1N7LZ63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS11150
gene id: 714067:GXN75_RS11150
uniprot id: A0A1N7J4J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS00640
gene id: 714067:GXN75_RS00640
uniprot id: A0A1N7MT42
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

714067:GXN75 RS03985
gene id: 714067:GXN75_RS03985
uniprot id: A0A1N7QAW9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

714067:GXN75 RS03145
gene id: 714067:GXN75_RS03145
uniprot id: A0A1N7PZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00790
gene id: 714067:GXN75_RS00790
uniprot id: A0A1N7MUD7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

714067:GXN75 RS04300
gene id: 714067:GXN75_RS04300
uniprot id: A0A1N7LLB3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS00620
gene id: 714067:GXN75_RS00620
uniprot id: A0A1N7MSX0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

714067:GXN75 RS06800
gene id: 714067:GXN75_RS06800
uniprot id: A0A1N7LZ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

714067:GXN75 RS10635
gene id: 714067:GXN75_RS10635
uniprot id: A0A1N7J1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

714067:GXN75 RS14965
gene id: 714067:GXN75_RS14965
uniprot id: A0A1N7Q5X3
names: Similarity
messages: Belongs to the UPF0111 family.

714067:GXN75 RS06525
gene id: 714067:GXN75_RS06525
uniprot id: A0A1N7LW50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS04070
gene id: 714067:GXN75_RS04070
uniprot id: A0A1N7LNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02705
gene id: 714067:GXN75_RS02705
uniprot id: A0A1N7NK59
names: Similarity
messages: Belongs to the ArsC family.

714067:GXN75 RS14060
gene id: 714067:GXN75_RS14060
uniprot id: A0A1N7KEJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS10575
gene id: 714067:GXN75_RS10575
uniprot id: A0A1N7J126
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

714067:GXN75 RS10250
gene id: 714067:GXN75_RS10250
uniprot id: A0A1N7IYZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

714067:GXN75 RS15625
gene id: 714067:GXN75_RS15625
uniprot id: A0A1N7PGL2
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS10790
gene id: 714067:GXN75_RS10790
uniprot id: A0A1N7J2F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

714067:GXN75 RS03975
gene id: 714067:GXN75_RS03975
uniprot id: A0A1N7QB39
names: Similarity
messages: Belongs to the manganese catalase family.

714067:GXN75 RS07040
gene id: 714067:GXN75_RS07040
uniprot id: A0A1N7M1B1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

714067:GXN75 RS07215
gene id: 714067:GXN75_RS07215
uniprot id: A0A1N7M393
names: Similarity
messages: Belongs to the peptidase A24 family.

714067:GXN75 RS13730
gene id: 714067:GXN75_RS13730
uniprot id: A0A1N7KIM6
names: Similarity
messages: Belongs to the transpeptidase family.

714067:GXN75 RS16305
gene id: 714067:GXN75_RS16305
uniprot id: A0A1N7JWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

714067:GXN75 RS11015
gene id: 714067:GXN75_RS11015
uniprot id: A0A1N7J3V0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

714067:GXN75 RS11785
gene id: 714067:GXN75_RS11785
uniprot id: A0A1N7Q465
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

714067:GXN75 RS17295
gene id: 714067:GXN75_RS17295
uniprot id: A0A1N7JI64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

714067:GXN75 RS08105
gene id: 714067:GXN75_RS08105
uniprot id: A0A1N7IM70
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

714067:GXN75 RS02910
gene id: 714067:GXN75_RS02910
uniprot id: A0A1N7NML4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

714067:GXN75 RS12125
gene id: 714067:GXN75_RS12125
uniprot id: A0A1N7PTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS04450
gene id: 714067:GXN75_RS04450
uniprot id: A0A1N7LJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

714067:GXN75 RS15555
gene id: 714067:GXN75_RS15555
uniprot id: A0A1N7PJS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

714067:GXN75 RS12355
gene id: 714067:GXN75_RS12355
uniprot id: A0A1N7PQK2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

714067:GXN75 RS07325
gene id: 714067:GXN75_RS07325
uniprot id: A0A1N7M499
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

714067:GXN75 RS02820
gene id: 714067:GXN75_RS02820
uniprot id: A0A1N7NLT3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

714067:GXN75 RS16990
gene id: 714067:GXN75_RS16990
uniprot id: A0A1N7JL55
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

714067:GXN75 RS07895
gene id: 714067:GXN75_RS07895
uniprot id: A0A1N7IL30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

714067:GXN75 RS08305
gene id: 714067:GXN75_RS08305
uniprot id: A0A1N7INI3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

714067:GXN75 RS10955
gene id: 714067:GXN75_RS10955
uniprot id: A0A1N7J3F0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

714067:GXN75 RS02215
gene id: 714067:GXN75_RS02215
uniprot id: A0A1N7PWW2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08585
gene id: 714067:GXN75_RS08585
uniprot id: A0A1N7IPQ8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

714067:GXN75 RS08945
gene id: 714067:GXN75_RS08945
uniprot id: A0A1N7IRM5
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13500
gene id: 714067:GXN75_RS13500
uniprot id: A0A1N7KLM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS08885
gene id: 714067:GXN75_RS08885
uniprot id: A0A1N7IR21
names: Similarity
messages: Belongs to the WrbA family.

714067:GXN75 RS08705
gene id: 714067:GXN75_RS08705
uniprot id: A0A1N7IQ77
names: Similarity
messages: Belongs to the UPF0302 family.

714067:GXN75 RS11565
gene id: 714067:GXN75_RS11565
uniprot id: A0A1N7J780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

714067:GXN75 RS03090
gene id: 714067:GXN75_RS03090
uniprot id: A0A1N7PZ65
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS03255
gene id: 714067:GXN75_RS03255
uniprot id: A0A1N7QA87
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

714067:GXN75 RS09770
gene id: 714067:GXN75_RS09770
uniprot id: A0A1N7IWF3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

714067:GXN75 RS11030
gene id: 714067:GXN75_RS11030
uniprot id: A0A1N7J3Z7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

714067:GXN75 RS14375
gene id: 714067:GXN75_RS14375
uniprot id: A0A1N7NC66
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

714067:GXN75 RS15755
gene id: 714067:GXN75_RS15755
uniprot id: A0A1N7PES2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07485
gene id: 714067:GXN75_RS07485
uniprot id: A0A1N7M669
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10600
gene id: 714067:GXN75_RS10600
uniprot id: A0A1N7J112
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

714067:GXN75 RS01440
gene id: 714067:GXN75_RS01440
uniprot id: A0A1N7N1C1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

714067:GXN75 RS06610
gene id: 714067:GXN75_RS06610
uniprot id: A0A1N7LX51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS10155
gene id: 714067:GXN75_RS10155
uniprot id: A0A1N7IYK3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

714067:GXN75 RS17420
gene id: 714067:GXN75_RS17420
uniprot id: A0A1N7JHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

714067:GXN75 RS00105
gene id: 714067:GXN75_RS00105
uniprot id: A0A1N7JGN3
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13325
gene id: 714067:GXN75_RS13325
uniprot id: A0A1N7KNI5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

714067:GXN75 RS16935
gene id: 714067:GXN75_RS16935
uniprot id: A0A1N7JM56
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

714067:GXN75 RS03665
gene id: 714067:GXN75_RS03665
uniprot id: A0A1N7NUM2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS02800
gene id: 714067:GXN75_RS02800
uniprot id: A0A1N7NLG6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

714067:GXN75 RS10175
gene id: 714067:GXN75_RS10175
uniprot id: A0A1N7IYK1
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS11075
gene id: 714067:GXN75_RS11075
uniprot id: A0A1N7J466
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

714067:GXN75 RS05660
gene id: 714067:GXN75_RS05660
uniprot id: A0A1N7MEA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

714067:GXN75 RS11155
gene id: 714067:GXN75_RS11155
uniprot id: A0A1N7J4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

714067:GXN75 RS16325
gene id: 714067:GXN75_RS16325
uniprot id: A0A1N7JWS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

714067:GXN75 RS00960
gene id: 714067:GXN75_RS00960
uniprot id: A0A1N7MWI7
names: Subcellular Location Annotation
messages: Secreted

714067:GXN75 RS11095
gene id: 714067:GXN75_RS11095
uniprot id: A0A1N7J4E0
names: Similarity
messages: Belongs to the YggT family.

714067:GXN75 RS11110
gene id: 714067:GXN75_RS11110
uniprot id: A0A1N7J4C8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

714067:GXN75 RS02660
gene id: 714067:GXN75_RS02660
uniprot id: A0A1N7NKB5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

714067:GXN75 RS09005
gene id: 714067:GXN75_RS09005
uniprot id: A0A1N7IRL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

714067:GXN75 RS06245
gene id: 714067:GXN75_RS06245
uniprot id: A0A1N7MKN0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

714067:GXN75 RS06935
gene id: 714067:GXN75_RS06935
uniprot id: A0A1N7M0A3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS11125
gene id: 714067:GXN75_RS11125
uniprot id: A0A1N7J4U6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

714067:GXN75 RS02150
gene id: 714067:GXN75_RS02150
uniprot id: A0A1N7P0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

714067:GXN75 RS01935
gene id: 714067:GXN75_RS01935
uniprot id: A0A1N7P3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

714067:GXN75 RS09905
gene id: 714067:GXN75_RS09905
uniprot id: A0A1N7IX87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS03535
gene id: 714067:GXN75_RS03535
uniprot id: A0A1N7NSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

714067:GXN75 RS05260
gene id: 714067:GXN75_RS05260
uniprot id: A0A1N7LA73
names: Similarity
messages: Belongs to the Nudix hydrolase family.

714067:GXN75 RS12175
gene id: 714067:GXN75_RS12175
uniprot id: A0A1N7PS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

714067:GXN75 RS08680
gene id: 714067:GXN75_RS08680
uniprot id: A0A1N7IQ10
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

714067:GXN75 RS00695
gene id: 714067:GXN75_RS00695
uniprot id: A0A1N7MU19
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10850
gene id: 714067:GXN75_RS10850
uniprot id: A0A1N7J2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

714067:GXN75 RS08500
gene id: 714067:GXN75_RS08500
uniprot id: A0A1N7IP94
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

714067:GXN75 RS02490
gene id: 714067:GXN75_RS02490
uniprot id: A0A1N7NI56
names: Similarity
messages: Belongs to the GARS family.

714067:GXN75 RS13855
gene id: 714067:GXN75_RS13855
uniprot id: A0A1N7KH17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS06255
gene id: 714067:GXN75_RS06255
uniprot id: A0A1N7MKU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

714067:GXN75 RS12330
gene id: 714067:GXN75_RS12330
uniprot id: A0A1N7PQV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

714067:GXN75 RS08310
gene id: 714067:GXN75_RS08310
uniprot id: A0A1N7INJ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

714067:GXN75 RS17465
gene id: 714067:GXN75_RS17465
uniprot id: A0A1N7J4G3
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08615
gene id: 714067:GXN75_RS08615
uniprot id: A0A1N7IPS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

714067:GXN75 RS10810
gene id: 714067:GXN75_RS10810
uniprot id: A0A1N7J2F4
names: Similarity
messages: Belongs to the RemA family.

714067:GXN75 RS11005
gene id: 714067:GXN75_RS11005
uniprot id: A0A1N7J3U0
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS06675
gene id: 714067:GXN75_RS06675
uniprot id: A0A1N7LXS9
names: Similarity
messages: Belongs to the thioesterase family.

714067:GXN75 RS07355
gene id: 714067:GXN75_RS07355
uniprot id: A0A1N7M4U3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

714067:GXN75 RS10295
gene id: 714067:GXN75_RS10295
uniprot id: A0A1N7IZ91
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

714067:GXN75 RS15020
gene id: 714067:GXN75_RS15020
uniprot id: A0A1N7Q786
names: Similarity
messages: Belongs to the peptidase S8 family.

714067:GXN75 RS03790
gene id: 714067:GXN75_RS03790
uniprot id: A0A1N7NVX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS08060
gene id: 714067:GXN75_RS08060
uniprot id: A0A1N7IM59
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

714067:GXN75 RS17030
gene id: 714067:GXN75_RS17030
uniprot id: A0A1N7JKN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS13275
gene id: 714067:GXN75_RS13275
uniprot id: A0A1N7KP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06750
gene id: 714067:GXN75_RS06750
uniprot id: A0A1N7LYC7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

714067:GXN75 RS00665
gene id: 714067:GXN75_RS00665
uniprot id: A0A1N7MTN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

714067:GXN75 RS03695
gene id: 714067:GXN75_RS03695
uniprot id: A0A1N7NUQ6
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

714067:GXN75 RS14960
gene id: 714067:GXN75_RS14960
uniprot id: A0A1N7Q5Z1
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10590
gene id: 714067:GXN75_RS10590
uniprot id: A0A1N7J125
names: Similarity
messages: Belongs to the fabD family.

714067:GXN75 RS01445
gene id: 714067:GXN75_RS01445
uniprot id: A0A1N7N1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS07720
gene id: 714067:GXN75_RS07720
uniprot id: A0A1N7IKH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

714067:GXN75 RS05870
gene id: 714067:GXN75_RS05870
uniprot id: A0A1N7MH11
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

714067:GXN75 RS05485
gene id: 714067:GXN75_RS05485
uniprot id: A0A1N7MCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS07715
gene id: 714067:GXN75_RS07715
uniprot id: A0A1N7IKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

714067:GXN75 RS03415
gene id: 714067:GXN75_RS03415
uniprot id: A0A1N7NR94
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

714067:GXN75 RS01325
gene id: 714067:GXN75_RS01325
uniprot id: A0A1N7N077
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

714067:GXN75 RS11375
gene id: 714067:GXN75_RS11375
uniprot id: A0A1N7J5R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

714067:GXN75 RS07675
gene id: 714067:GXN75_RS07675
uniprot id: A0A1N7IK71
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

714067:GXN75 RS08110
gene id: 714067:GXN75_RS08110
uniprot id: A0A1N7IM60
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

714067:GXN75 RS10900
gene id: 714067:GXN75_RS10900
uniprot id: A0A1N7J3D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS11865
gene id: 714067:GXN75_RS11865
uniprot id: A0A1N7Q4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

714067:GXN75 RS09305
gene id: 714067:GXN75_RS09305
uniprot id: A0A1N7ITF6
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

714067:GXN75 RS01360
gene id: 714067:GXN75_RS01360
uniprot id: A0A1N7N0P9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

714067:GXN75 RS06215
gene id: 714067:GXN75_RS06215
uniprot id: A0A1N7MKL1
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

714067:GXN75 RS13170
gene id: 714067:GXN75_RS13170
uniprot id: A0A1N7KQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

714067:GXN75 RS11120
gene id: 714067:GXN75_RS11120
uniprot id: A0A1N7J4F9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

714067:GXN75 RS05620
gene id: 714067:GXN75_RS05620
uniprot id: A0A1N7ME36
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

714067:GXN75 RS16940
gene id: 714067:GXN75_RS16940
uniprot id: A0A1N7JLV7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

714067:GXN75 RS10880
gene id: 714067:GXN75_RS10880
uniprot id: A0A1N7J322
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

714067:GXN75 RS13540
gene id: 714067:GXN75_RS13540
uniprot id: A0A1N7KKR7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS04835
gene id: 714067:GXN75_RS04835
uniprot id: A0A1N7LEY7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS17380
gene id: 714067:GXN75_RS17380
uniprot id: A0A1N7JHF6
names: Similarity
messages: Belongs to the ParB family.

714067:GXN75 RS03260
gene id: 714067:GXN75_RS03260
uniprot id: A0A1N7QAQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

714067:GXN75 RS14215
gene id: 714067:GXN75_RS14215
uniprot id: A0A1N7NEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08510
gene id: 714067:GXN75_RS08510
uniprot id: A0A1N7IP95
names: Similarity
messages: Belongs to the asparaginase 1 family.

714067:GXN75 RS14035
gene id: 714067:GXN75_RS14035
uniprot id: A0A1N7KEW3
names: Similarity
messages: Belongs to the asp23 family.

714067:GXN75 RS13715
gene id: 714067:GXN75_RS13715
uniprot id: A0A1N7KIS6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16225
gene id: 714067:GXN75_RS16225
uniprot id: A0A1N7JY77
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

714067:GXN75 RS01855
gene id: 714067:GXN75_RS01855
uniprot id: A0A1N7P4Q1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

714067:GXN75 RS15895
gene id: 714067:GXN75_RS15895
uniprot id: A0A1N7PDE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

714067:GXN75 RS00630
gene id: 714067:GXN75_RS00630
uniprot id: A0A1N7MT15
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

714067:GXN75 RS06955
gene id: 714067:GXN75_RS06955
uniprot id: A0A1N7M0D5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

714067:GXN75 RS03070
gene id: 714067:GXN75_RS03070
uniprot id: A0A1N7PYY7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16835
gene id: 714067:GXN75_RS16835
uniprot id: A0A1N7JND6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

714067:GXN75 RS12310
gene id: 714067:GXN75_RS12310
uniprot id: A0A1N7PRE0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

714067:GXN75 RS01860
gene id: 714067:GXN75_RS01860
uniprot id: A0A1N7P4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

714067:GXN75 RS09670
gene id: 714067:GXN75_RS09670
uniprot id: A0A1N7IVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

714067:GXN75 RS03730
gene id: 714067:GXN75_RS03730
uniprot id: A0A1N7NV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

714067:GXN75 RS10875
gene id: 714067:GXN75_RS10875
uniprot id: A0A1N7J374
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

714067:GXN75 RS15605
gene id: 714067:GXN75_RS15605
uniprot id: A0A1N7PGK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS08800
gene id: 714067:GXN75_RS08800
uniprot id: A0A1N7IQU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

714067:GXN75 RS09890
gene id: 714067:GXN75_RS09890
uniprot id: A0A1N7IX96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

714067:GXN75 RS08670
gene id: 714067:GXN75_RS08670
uniprot id: A0A1N7IQ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

714067:GXN75 RS07350
gene id: 714067:GXN75_RS07350
uniprot id: A0A1N7M4S6
names: Similarity
messages: Belongs to the UPF0735 family.

714067:GXN75 RS17400
gene id: 714067:GXN75_RS17400
uniprot id: A0A1N7JHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

714067:GXN75 RS17040
gene id: 714067:GXN75_RS17040
uniprot id: A0A1N7JKJ5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

714067:GXN75 RS09350
gene id: 714067:GXN75_RS09350
uniprot id: A0A1N7ITJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS01240
gene id: 714067:GXN75_RS01240
uniprot id: A0A1N7MZE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

714067:GXN75 RS15115
gene id: 714067:GXN75_RS15115
uniprot id: A0A1N7Q9F9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

714067:GXN75 RS09435
gene id: 714067:GXN75_RS09435
uniprot id: A0A1N7IU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

714067:GXN75 RS12015
gene id: 714067:GXN75_RS12015
uniprot id: A0A1N7Q267
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS05305
gene id: 714067:GXN75_RS05305
uniprot id: A0A1N7L9H1
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

714067:GXN75 RS03800
gene id: 714067:GXN75_RS03800
uniprot id: A0A1N7NW47
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

714067:GXN75 RS09695
gene id: 714067:GXN75_RS09695
uniprot id: A0A1N7IVW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

714067:GXN75 RS11770
gene id: 714067:GXN75_RS11770
uniprot id: A0A1N7Q4W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

714067:GXN75 RS07320
gene id: 714067:GXN75_RS07320
uniprot id: A0A1N7M495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01170
gene id: 714067:GXN75_RS01170
uniprot id: A0A1N7MYP6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS08635
gene id: 714067:GXN75_RS08635
uniprot id: A0A1N7IQ57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

714067:GXN75 RS03615
gene id: 714067:GXN75_RS03615
uniprot id: A0A1N7NTS3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

714067:GXN75 RS08775
gene id: 714067:GXN75_RS08775
uniprot id: A0A1N7IQQ6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

714067:GXN75 RS13360
gene id: 714067:GXN75_RS13360
uniprot id: A0A1N7KN10
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

714067:GXN75 RS01955
gene id: 714067:GXN75_RS01955
uniprot id: A0A1N7P3N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

714067:GXN75 RS15855
gene id: 714067:GXN75_RS15855
uniprot id: A0A1N7PDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

714067:GXN75 RS00490
gene id: 714067:GXN75_RS00490
uniprot id: A0A1N7JEP2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

714067:GXN75 RS13640
gene id: 714067:GXN75_RS13640
uniprot id: A0A1N7KJL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS12130
gene id: 714067:GXN75_RS12130
uniprot id: A0A1N7PSU6
names: Similarity
messages: Belongs to the peptidase C40 family.

714067:GXN75 RS08620
gene id: 714067:GXN75_RS08620
uniprot id: A0A1N7IPV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

714067:GXN75 RS05250
gene id: 714067:GXN75_RS05250
uniprot id: A0A1N7LAE6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16750
gene id: 714067:GXN75_RS16750
uniprot id: A0A1N7JPM6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

714067:GXN75 RS06880
gene id: 714067:GXN75_RS06880
uniprot id: A0A1N7LZL6
names: Similarity
messages: Belongs to the thioredoxin family.

714067:GXN75 RS16875
gene id: 714067:GXN75_RS16875
uniprot id: A0A1N7JMT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

714067:GXN75 RS04545
gene id: 714067:GXN75_RS04545
uniprot id: A0A1N7LIJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

714067:GXN75 RS10320
gene id: 714067:GXN75_RS10320
uniprot id: A0A1N7IZM6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS06605
gene id: 714067:GXN75_RS06605
uniprot id: A0A1N7LXB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

714067:GXN75 RS16840
gene id: 714067:GXN75_RS16840
uniprot id: A0A1N7JN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

714067:GXN75 RS07240
gene id: 714067:GXN75_RS07240
uniprot id: A0A1N7M3E6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

714067:GXN75 RS05235
gene id: 714067:GXN75_RS05235
uniprot id: A0A1N7LAK9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

714067:GXN75 RS09235
gene id: 714067:GXN75_RS09235
uniprot id: A0A1N7ISV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS08850
gene id: 714067:GXN75_RS08850
uniprot id: A0A1N7IR43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

714067:GXN75 RS11390
gene id: 714067:GXN75_RS11390
uniprot id: A0A1N7J5X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

714067:GXN75 RS12335
gene id: 714067:GXN75_RS12335
uniprot id: A0A1N7PR32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

714067:GXN75 RS08405
gene id: 714067:GXN75_RS08405
uniprot id: A0A1N7INS3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

714067:GXN75 RS01350
gene id: 714067:GXN75_RS01350
uniprot id: A0A1N7N0G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS09660
gene id: 714067:GXN75_RS09660
uniprot id: A0A1N7IVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

714067:GXN75 RS02180
gene id: 714067:GXN75_RS02180
uniprot id: A0A1N7PX89
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

714067:GXN75 RS07395
gene id: 714067:GXN75_RS07395
uniprot id: A0A1N7M5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02470
gene id: 714067:GXN75_RS02470
uniprot id: A0A1N7NI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

714067:GXN75 RS06950
gene id: 714067:GXN75_RS06950
uniprot id: A0A1N7M0B4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

714067:GXN75 RS11210
gene id: 714067:GXN75_RS11210
uniprot id: A0A1N7J4W7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

714067:GXN75 RS01595
gene id: 714067:GXN75_RS01595
uniprot id: A0A1N7P865
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

714067:GXN75 RS12705
gene id: 714067:GXN75_RS12705
uniprot id: A0A1N7KWD9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

714067:GXN75 RS14290
gene id: 714067:GXN75_RS14290
uniprot id: A0A1N7ND54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06775
gene id: 714067:GXN75_RS06775
uniprot id: A0A1N7LYL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

714067:GXN75 RS10450
gene id: 714067:GXN75_RS10450
uniprot id: A0A1N7J073
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

714067:GXN75 RS00020
gene id: 714067:GXN75_RS00020
uniprot id: A0A1N7JH38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

714067:GXN75 RS07035
gene id: 714067:GXN75_RS07035
uniprot id: A0A1N7M191
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

714067:GXN75 RS06300
gene id: 714067:GXN75_RS06300
uniprot id: A0A1N7MKV8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

714067:GXN75 RS11025
gene id: 714067:GXN75_RS11025
uniprot id: A0A1N7J3Y8
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

714067:GXN75 RS05410
gene id: 714067:GXN75_RS05410
uniprot id: A0A1N7L8P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

714067:GXN75 RS02700
gene id: 714067:GXN75_RS02700
uniprot id: A0A1N7NKN2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

714067:GXN75 RS07640
gene id: 714067:GXN75_RS07640
uniprot id: A0A1N7IK14
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

714067:GXN75 RS00645
gene id: 714067:GXN75_RS00645
uniprot id: A0A1N7MTX3
names: Similarity
messages: Belongs to the RutC family.

714067:GXN75 RS07285
gene id: 714067:GXN75_RS07285
uniprot id: A0A1N7M3T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

714067:GXN75 RS14450
gene id: 714067:GXN75_RS14450
uniprot id: A0A1N7NBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

714067:GXN75 RS06520
gene id: 714067:GXN75_RS06520
uniprot id: A0A1N7LW23
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS06805
gene id: 714067:GXN75_RS06805
uniprot id: A0A1N7LZ36
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10800
gene id: 714067:GXN75_RS10800
uniprot id: A0A1N7J2R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

714067:GXN75 RS13340
gene id: 714067:GXN75_RS13340
uniprot id: A0A1N7KNK0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

714067:GXN75 RS09580
gene id: 714067:GXN75_RS09580
uniprot id: A0A1N7IV36
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

714067:GXN75 RS04955
gene id: 714067:GXN75_RS04955
uniprot id: A0A1N7LDN3
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

714067:GXN75 RS07910
gene id: 714067:GXN75_RS07910
uniprot id: A0A1N7IL56
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

714067:GXN75 RS16475
gene id: 714067:GXN75_RS16475
uniprot id: A0A1N7JUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

714067:GXN75 RS01845
gene id: 714067:GXN75_RS01845
uniprot id: A0A1N7P4S4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

714067:GXN75 RS17190
gene id: 714067:GXN75_RS17190
uniprot id: A0A1N7JJ37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS08660
gene id: 714067:GXN75_RS08660
uniprot id: A0A1N7IQ09
names: Similarity
messages: Belongs to the TrpC family.

714067:GXN75 RS10580
gene id: 714067:GXN75_RS10580
uniprot id: A0A1N7J1E2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

714067:GXN75 RS14905
gene id: 714067:GXN75_RS14905
uniprot id: A0A1N7N6K7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

714067:GXN75 RS16915
gene id: 714067:GXN75_RS16915
uniprot id: A0A1N7JM83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

714067:GXN75 RS01420
gene id: 714067:GXN75_RS01420
uniprot id: A0A1N7N1D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

714067:GXN75 RS03120
gene id: 714067:GXN75_RS03120
uniprot id: A0A1N7PZI6
names: Similarity
messages: Belongs to the ThiD family.

714067:GXN75 RS07440
gene id: 714067:GXN75_RS07440
uniprot id: A0A1N7M5X9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS15465
gene id: 714067:GXN75_RS15465
uniprot id: A0A1N7PKP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08415
gene id: 714067:GXN75_RS08415
uniprot id: A0A1N7INW2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS05910
gene id: 714067:GXN75_RS05910
uniprot id: A0A1N7MGZ4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

714067:GXN75 RS08920
gene id: 714067:GXN75_RS08920
uniprot id: A0A1N7IRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

714067:GXN75 RS10260
gene id: 714067:GXN75_RS10260
uniprot id: A0A1N7IZ01
names: Similarity
messages: Belongs to the CdaR family.

714067:GXN75 RS13795
gene id: 714067:GXN75_RS13795
uniprot id: A0A1N7KI26
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS15965
gene id: 714067:GXN75_RS15965
uniprot id: A0A1N7PD20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

714067:GXN75 RS06395
gene id: 714067:GXN75_RS06395
uniprot id: A0A1N7MME3
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

714067:GXN75 RS08550
gene id: 714067:GXN75_RS08550
uniprot id: A0A1N7IPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

714067:GXN75 RS17010
gene id: 714067:GXN75_RS17010
uniprot id: A0A1N7JKT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS10280
gene id: 714067:GXN75_RS10280
uniprot id: A0A1N7IZJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

714067:GXN75 RS13990
gene id: 714067:GXN75_RS13990
uniprot id: A0A1N7KFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00845
gene id: 714067:GXN75_RS00845
uniprot id: A0A1N7MV09
names: Subcellular Location Annotation
messages: Secreted

714067:GXN75 RS05765
gene id: 714067:GXN75_RS05765
uniprot id: A0A1N7MFB3
names: Similarity
messages: Belongs to the UPF0229 family.

714067:GXN75 RS03865
gene id: 714067:GXN75_RS03865
uniprot id: A0A1N7NWH6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

714067:GXN75 RS01395
gene id: 714067:GXN75_RS01395
uniprot id: A0A1N7N0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

714067:GXN75 RS04930
gene id: 714067:GXN75_RS04930
uniprot id: A0A1N7LDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00120
gene id: 714067:GXN75_RS00120
uniprot id: A0A1N7JGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS07375
gene id: 714067:GXN75_RS07375
uniprot id: A0A1N7M4V7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS03860
gene id: 714067:GXN75_RS03860
uniprot id: A0A1N7NWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06645
gene id: 714067:GXN75_RS06645
uniprot id: A0A1N7LXF6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

714067:GXN75 RS09445
gene id: 714067:GXN75_RS09445
uniprot id: A0A1N7IU68
names: Similarity
messages: Belongs to the DEAD box helicase family.

714067:GXN75 RS16805
gene id: 714067:GXN75_RS16805
uniprot id: A0A1N7JNZ1
names: Similarity
messages: Belongs to the YciI family.

714067:GXN75 RS13235
gene id: 714067:GXN75_RS13235
uniprot id: A0A1N7KPF2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS06515
gene id: 714067:GXN75_RS06515
uniprot id: A0A1N7LVW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

714067:GXN75 RS08050
gene id: 714067:GXN75_RS08050
uniprot id: A0A1N7ILV4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

714067:GXN75 RS10550
gene id: 714067:GXN75_RS10550
uniprot id: A0A1N7J127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

714067:GXN75 RS09430
gene id: 714067:GXN75_RS09430
uniprot id: A0A1N7IU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

714067:GXN75 RS09310
gene id: 714067:GXN75_RS09310
uniprot id: A0A1N7ITG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

714067:GXN75 RS10775
gene id: 714067:GXN75_RS10775
uniprot id: A0A1N7J2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

714067:GXN75 RS09325
gene id: 714067:GXN75_RS09325
uniprot id: A0A1N7ITM3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

714067:GXN75 RS14675
gene id: 714067:GXN75_RS14675
uniprot id: A0A1N7N9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

714067:GXN75 RS11465
gene id: 714067:GXN75_RS11465
uniprot id: A0A1N7J6G6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

714067:GXN75 RS07600
gene id: 714067:GXN75_RS07600
uniprot id: A0A1N7M7L6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08805
gene id: 714067:GXN75_RS08805
uniprot id: A0A1N7IQK4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

714067:GXN75 RS17405
gene id: 714067:GXN75_RS17405
uniprot id: A0A1N7JHD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS00625
gene id: 714067:GXN75_RS00625
uniprot id: A0A1N7MT87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

714067:GXN75 RS10660
gene id: 714067:GXN75_RS10660
uniprot id: A0A1N7J1T0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

714067:GXN75 RS09220
gene id: 714067:GXN75_RS09220
uniprot id: A0A1N7ISZ5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

714067:GXN75 RS08725
gene id: 714067:GXN75_RS08725
uniprot id: A0A1N7IQA2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS04095
gene id: 714067:GXN75_RS04095
uniprot id: A0A1N7LN68
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS01335
gene id: 714067:GXN75_RS01335
uniprot id: A0A1N7N0B3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

714067:GXN75 RS04040
gene id: 714067:GXN75_RS04040
uniprot id: A0A1N7LNM9
names: Similarity
messages: Belongs to the UPF0045 family.

714067:GXN75 RS11055
gene id: 714067:GXN75_RS11055
uniprot id: A0A1N7J4F1
names: Similarity
messages: Belongs to the AHA1 family.

714067:GXN75 RS14380
gene id: 714067:GXN75_RS14380
uniprot id: A0A1N7NCB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

714067:GXN75 RS01495
gene id: 714067:GXN75_RS01495
uniprot id: A0A1N7N1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

714067:GXN75 RS00660
gene id: 714067:GXN75_RS00660
uniprot id: A0A1N7MT82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

714067:GXN75 RS06380
gene id: 714067:GXN75_RS06380
uniprot id: A0A1N7MLU9
names: Similarity
messages: Belongs to the LOG family.

714067:GXN75 RS02355
gene id: 714067:GXN75_RS02355
uniprot id: A0A1N7PW51
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16775
gene id: 714067:GXN75_RS16775
uniprot id: A0A1N7JP59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

714067:GXN75 RS14235
gene id: 714067:GXN75_RS14235
uniprot id: A0A1N7NDY1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

714067:GXN75 RS16945
gene id: 714067:GXN75_RS16945
uniprot id: A0A1N7JLT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS08445
gene id: 714067:GXN75_RS08445
uniprot id: A0A1N7INY1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS07555
gene id: 714067:GXN75_RS07555
uniprot id: A0A1N7M6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

714067:GXN75 RS13710
gene id: 714067:GXN75_RS13710
uniprot id: A0A1N7KJ13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10490
gene id: 714067:GXN75_RS10490
uniprot id: A0A1N7J0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

714067:GXN75 RS11765
gene id: 714067:GXN75_RS11765
uniprot id: A0A1N7Q459
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

714067:GXN75 RS11760
gene id: 714067:GXN75_RS11760
uniprot id: A0A1N7Q439
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

714067:GXN75 RS17300
gene id: 714067:GXN75_RS17300
uniprot id: A0A1N7JIA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

714067:GXN75 RS12525
gene id: 714067:GXN75_RS12525
uniprot id: A0A1N7KYK8
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

714067:GXN75 RS09555
gene id: 714067:GXN75_RS09555
uniprot id: A0A1N7IUX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS15940
gene id: 714067:GXN75_RS15940
uniprot id: A0A1N7PCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06925
gene id: 714067:GXN75_RS06925
uniprot id: A0A1N7LZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10785
gene id: 714067:GXN75_RS10785
uniprot id: A0A1N7J286
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

714067:GXN75 RS08930
gene id: 714067:GXN75_RS08930
uniprot id: A0A1N7IR90
names: Similarity
messages: Belongs to the acylphosphatase family.

714067:GXN75 RS02320
gene id: 714067:GXN75_RS02320
uniprot id: A0A1N7PVY6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

714067:GXN75 RS07590
gene id: 714067:GXN75_RS07590
uniprot id: A0A1N7M7B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

714067:GXN75 RS07050
gene id: 714067:GXN75_RS07050
uniprot id: A0A1N7M1E4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

714067:GXN75 RS12370
gene id: 714067:GXN75_RS12370
uniprot id: A0A1N7PQF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

714067:GXN75 RS01635
gene id: 714067:GXN75_RS01635
uniprot id: A0A1N7P7F9
names: Similarity
messages: Belongs to the AHA1 family.

714067:GXN75 RS14355
gene id: 714067:GXN75_RS14355
uniprot id: A0A1N7NCL1
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13335
gene id: 714067:GXN75_RS13335
uniprot id: A0A1N7KNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS12985
gene id: 714067:GXN75_RS12985
uniprot id: A0A1N7KT89
names: Similarity
messages: Belongs to the ClpA/ClpB family.

714067:GXN75 RS03550
gene id: 714067:GXN75_RS03550
uniprot id: A0A1N7NTB7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08870
gene id: 714067:GXN75_RS08870
uniprot id: A0A1N7IR81
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

714067:GXN75 RS13555
gene id: 714067:GXN75_RS13555
uniprot id: A0A1N7KKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

714067:GXN75 RS10745
gene id: 714067:GXN75_RS10745
uniprot id: A0A1N7J1Z7
names: Similarity
messages: Belongs to the glutamate synthase family.

714067:GXN75 RS01120
gene id: 714067:GXN75_RS01120
uniprot id: A0A1N7MYB6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

714067:GXN75 RS14915
gene id: 714067:GXN75_RS14915
uniprot id: A0A1N7N6H1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

714067:GXN75 RS02915
gene id: 714067:GXN75_RS02915
uniprot id: A0A1N7NMG8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

714067:GXN75 RS01895
gene id: 714067:GXN75_RS01895
uniprot id: A0A1N7P4A4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

714067:GXN75 RS08295
gene id: 714067:GXN75_RS08295
uniprot id: A0A1N7IN62
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

714067:GXN75 RS16015
gene id: 714067:GXN75_RS16015
uniprot id: A0A1N7PBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

714067:GXN75 RS00635
gene id: 714067:GXN75_RS00635
uniprot id: A0A1N7MTU7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

714067:GXN75 RS01670
gene id: 714067:GXN75_RS01670
uniprot id: A0A1N7P6U0
names: Similarity
messages: Belongs to the PemK/MazF family.

714067:GXN75 RS00760
gene id: 714067:GXN75_RS00760
uniprot id: A0A1N7MU66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

714067:GXN75 RS06730
gene id: 714067:GXN75_RS06730
uniprot id: A0A1N7LYB8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

714067:GXN75 RS16525
gene id: 714067:GXN75_RS16525
uniprot id: A0A1N7JT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

714067:GXN75 RS17020
gene id: 714067:GXN75_RS17020
uniprot id: A0A1N7JKV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS12400
gene id: 714067:GXN75_RS12400
uniprot id: A0A1N7L067
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

714067:GXN75 RS16735
gene id: 714067:GXN75_RS16735
uniprot id: A0A1N7JPS7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10830
gene id: 714067:GXN75_RS10830
uniprot id: A0A1N7J2N5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08740
gene id: 714067:GXN75_RS08740
uniprot id: A0A1N7IQE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS05690
gene id: 714067:GXN75_RS05690
uniprot id: A0A1N7MEZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

714067:GXN75 RS06600
gene id: 714067:GXN75_RS06600
uniprot id: A0A1N7LX09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS12710
gene id: 714067:GXN75_RS12710
uniprot id: A0A1N7KW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01760
gene id: 714067:GXN75_RS01760
uniprot id: A0A1N7P5S6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07540
gene id: 714067:GXN75_RS07540
uniprot id: A0A1N7M6Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

714067:GXN75 RS05790
gene id: 714067:GXN75_RS05790
uniprot id: A0A1N7MFP5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

714067:GXN75 RS12825
gene id: 714067:GXN75_RS12825
uniprot id: A0A1N7KV96
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

714067:GXN75 RS06040
gene id: 714067:GXN75_RS06040
uniprot id: A0A1N7MIP7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS05400
gene id: 714067:GXN75_RS05400
uniprot id: A0A1N7L8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

714067:GXN75 RS13210
gene id: 714067:GXN75_RS13210
uniprot id: A0A1N7KPN3
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS04270
gene id: 714067:GXN75_RS04270
uniprot id: A0A1N7LLM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS05280
gene id: 714067:GXN75_RS05280
uniprot id: A0A1N7LA03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

714067:GXN75 RS09885
gene id: 714067:GXN75_RS09885
uniprot id: A0A1N7IX86
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS02360
gene id: 714067:GXN75_RS02360
uniprot id: A0A1N7PVS1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

714067:GXN75 RS00530
gene id: 714067:GXN75_RS00530
uniprot id: A0A1N7MS93
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

714067:GXN75 RS15675
gene id: 714067:GXN75_RS15675
uniprot id: A0A1N7PFW6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS10165
gene id: 714067:GXN75_RS10165
uniprot id: A0A1N7IYU4
names: Similarity
messages: Belongs to the UxaA family.

714067:GXN75 RS09600
gene id: 714067:GXN75_RS09600
uniprot id: A0A1N7IVB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

714067:GXN75 RS00060
gene id: 714067:GXN75_RS00060
uniprot id: A0A1N7JH62
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS09775
gene id: 714067:GXN75_RS09775
uniprot id: A0A1N7IWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

714067:GXN75 RS11930
gene id: 714067:GXN75_RS11930
uniprot id: A0A1N7Q2L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

714067:GXN75 RS02270
gene id: 714067:GXN75_RS02270
uniprot id: A0A1N7PWI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

714067:GXN75 RS01915
gene id: 714067:GXN75_RS01915
uniprot id: A0A1N7P479
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS16470
gene id: 714067:GXN75_RS16470
uniprot id: A0A1N7JU24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

714067:GXN75 RS10485
gene id: 714067:GXN75_RS10485
uniprot id: A0A1N7J0P0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

714067:GXN75 RS07090
gene id: 714067:GXN75_RS07090
uniprot id: A0A1N7M1Q0
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS14115
gene id: 714067:GXN75_RS14115
uniprot id: A0A1N7KDJ9
names: Similarity
messages: Belongs to the peptidase M29 family.

714067:GXN75 RS06915
gene id: 714067:GXN75_RS06915
uniprot id: A0A1N7LZY6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

714067:GXN75 RS15985
gene id: 714067:GXN75_RS15985
uniprot id: A0A1N7PCE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS01390
gene id: 714067:GXN75_RS01390
uniprot id: A0A1N7N108
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS09205
gene id: 714067:GXN75_RS09205
uniprot id: A0A1N7IT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

714067:GXN75 RS16235
gene id: 714067:GXN75_RS16235
uniprot id: A0A1N7JY10
names: Similarity
messages: Belongs to the sigma-54 factor family.

714067:GXN75 RS12485
gene id: 714067:GXN75_RS12485
uniprot id: A0A1N7KZ85
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

714067:GXN75 RS06500
gene id: 714067:GXN75_RS06500
uniprot id: A0A1N7LVN7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS01330
gene id: 714067:GXN75_RS01330
uniprot id: A0A1N7N0B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS03370
gene id: 714067:GXN75_RS03370
uniprot id: A0A1N7Q7T2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

714067:GXN75 RS03350
gene id: 714067:GXN75_RS03350
uniprot id: A0A1N7Q8D3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

714067:GXN75 RS03475
gene id: 714067:GXN75_RS03475
uniprot id: A0A1N7NRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

714067:GXN75 RS06205
gene id: 714067:GXN75_RS06205
uniprot id: A0A1N7MKB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

714067:GXN75 RS04670
gene id: 714067:GXN75_RS04670
uniprot id: A0A1N7LGZ1
names: Similarity
messages: Belongs to the manganese catalase family.

714067:GXN75 RS16010
gene id: 714067:GXN75_RS16010
uniprot id: A0A1N7PBP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS17290
gene id: 714067:GXN75_RS17290
uniprot id: A0A1N7JIC9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

714067:GXN75 RS13395
gene id: 714067:GXN75_RS13395
uniprot id: A0A1N7KMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

714067:GXN75 RS09680
gene id: 714067:GXN75_RS09680
uniprot id: A0A1N7IVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

714067:GXN75 RS07005
gene id: 714067:GXN75_RS07005
uniprot id: A0A1N7M0X7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

714067:GXN75 RS15740
gene id: 714067:GXN75_RS15740
uniprot id: A0A1N7PEW1
names: Similarity
messages: Belongs to the phosphopentomutase family.

714067:GXN75 RS05240
gene id: 714067:GXN75_RS05240
uniprot id: A0A1N7LAA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

714067:GXN75 RS05805
gene id: 714067:GXN75_RS05805
uniprot id: A0A1N7MG20
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

714067:GXN75 RS07605
gene id: 714067:GXN75_RS07605
uniprot id: A0A1N7M7D1
names: Similarity
messages: Belongs to the RecJ family.

714067:GXN75 RS02595
gene id: 714067:GXN75_RS02595
uniprot id: A0A1N7NIZ2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

714067:GXN75 RS02795
gene id: 714067:GXN75_RS02795
uniprot id: A0A1N7NL63
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

714067:GXN75 RS15255
gene id: 714067:GXN75_RS15255
uniprot id: A0A1N7PN54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

714067:GXN75 RS17365
gene id: 714067:GXN75_RS17365
uniprot id: A0A1N7JHS2
names: Similarity
messages: Belongs to the ParB family.

714067:GXN75 RS16690
gene id: 714067:GXN75_RS16690
uniprot id: A0A1N7JQS2
names: Similarity
messages: Belongs to the IMPACT family.

714067:GXN75 RS11800
gene id: 714067:GXN75_RS11800
uniprot id: A0A1N7Q4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

714067:GXN75 RS17080
gene id: 714067:GXN75_RS17080
uniprot id: A0A1N7JK66
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

714067:GXN75 RS16275
gene id: 714067:GXN75_RS16275
uniprot id: A0A1N7JXH7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

714067:GXN75 RS12350
gene id: 714067:GXN75_RS12350
uniprot id: A0A1N7PQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS06585
gene id: 714067:GXN75_RS06585
uniprot id: A0A1N7LWV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS06725
gene id: 714067:GXN75_RS06725
uniprot id: A0A1N7LY59
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

714067:GXN75 RS11870
gene id: 714067:GXN75_RS11870
uniprot id: A0A1N7Q4W5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS10755
gene id: 714067:GXN75_RS10755
uniprot id: A0A1N7J222
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

714067:GXN75 RS16905
gene id: 714067:GXN75_RS16905
uniprot id: A0A1N7JME4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

714067:GXN75 RS00055
gene id: 714067:GXN75_RS00055
uniprot id: A0A1N7JH83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

714067:GXN75 RS02185
gene id: 714067:GXN75_RS02185
uniprot id: A0A1N7PX84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

714067:GXN75 RS00890
gene id: 714067:GXN75_RS00890
uniprot id: A0A1N7MVJ3
names: Similarity
messages: Belongs to the peptidase A24 family.

714067:GXN75 RS10480
gene id: 714067:GXN75_RS10480
uniprot id: A0A1N7J0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS14090
gene id: 714067:GXN75_RS14090
uniprot id: A0A1N7KDV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

714067:GXN75 RS08650
gene id: 714067:GXN75_RS08650
uniprot id: A0A1N7IPX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

714067:GXN75 RS08625
gene id: 714067:GXN75_RS08625
uniprot id: A0A1N7IPT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

714067:GXN75 RS07490
gene id: 714067:GXN75_RS07490
uniprot id: A0A1N7M659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00050
gene id: 714067:GXN75_RS00050
uniprot id: A0A1N7JH40
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

714067:GXN75 RS10505
gene id: 714067:GXN75_RS10505
uniprot id: A0A1N7J0U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

714067:GXN75 RS00045
gene id: 714067:GXN75_RS00045
uniprot id: A0A1N7JHC2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

714067:GXN75 RS09620
gene id: 714067:GXN75_RS09620
uniprot id: A0A1N7IVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

714067:GXN75 RS11325
gene id: 714067:GXN75_RS11325
uniprot id: A0A1N7J5W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

714067:GXN75 RS02465
gene id: 714067:GXN75_RS02465
uniprot id: A0A1N7NHL6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

714067:GXN75 RS02445
gene id: 714067:GXN75_RS02445
uniprot id: A0A1N7NHV1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

714067:GXN75 RS06270
gene id: 714067:GXN75_RS06270
uniprot id: A0A1N7MKP5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

714067:GXN75 RS07360
gene id: 714067:GXN75_RS07360
uniprot id: A0A1N7M4W5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

714067:GXN75 RS00090
gene id: 714067:GXN75_RS00090
uniprot id: A0A1N7JGZ1
names: Similarity
messages: Belongs to the asparagine synthetase family.

714067:GXN75 RS08915
gene id: 714067:GXN75_RS08915
uniprot id: A0A1N7IRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

714067:GXN75 RS00770
gene id: 714067:GXN75_RS00770
uniprot id: A0A1N7MUC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

714067:GXN75 RS09450
gene id: 714067:GXN75_RS09450
uniprot id: A0A1N7IU80
names: Similarity
messages: Belongs to the CinA family.

714067:GXN75 RS01870
gene id: 714067:GXN75_RS01870
uniprot id: A0A1N7P4F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

714067:GXN75 RS10140
gene id: 714067:GXN75_RS10140
uniprot id: A0A1N7IYQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS15665
gene id: 714067:GXN75_RS15665
uniprot id: A0A1N7PG55
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

714067:GXN75 RS15610
gene id: 714067:GXN75_RS15610
uniprot id: A0A1N7PGQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

714067:GXN75 RS10035
gene id: 714067:GXN75_RS10035
uniprot id: A0A1N7IXZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16755
gene id: 714067:GXN75_RS16755
uniprot id: A0A1N7JPJ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

714067:GXN75 RS12685
gene id: 714067:GXN75_RS12685
uniprot id: A0A1N7KWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

714067:GXN75 RS04720
gene id: 714067:GXN75_RS04720
uniprot id: A0A1N7LGA2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS15595
gene id: 714067:GXN75_RS15595
uniprot id: A0A1N7PGN3
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS01250
gene id: 714067:GXN75_RS01250
uniprot id: A0A1N7MZL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

714067:GXN75 RS06870
gene id: 714067:GXN75_RS06870
uniprot id: A0A1N7LZF6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

714067:GXN75 RS16620
gene id: 714067:GXN75_RS16620
uniprot id: A0A1N7JRY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

714067:GXN75 RS10585
gene id: 714067:GXN75_RS10585
uniprot id: A0A1N7J0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

714067:GXN75 RS00035
gene id: 714067:GXN75_RS00035
uniprot id: A0A1N7JH54
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

714067:GXN75 RS04520
gene id: 714067:GXN75_RS04520
uniprot id: A0A1N7LIT4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS09720
gene id: 714067:GXN75_RS09720
uniprot id: A0A1N7IW27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

714067:GXN75 RS04830
gene id: 714067:GXN75_RS04830
uniprot id: A0A1N7LF05
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

714067:GXN75 RS01735
gene id: 714067:GXN75_RS01735
uniprot id: A0A1N7P5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

714067:GXN75 RS08665
gene id: 714067:GXN75_RS08665
uniprot id: A0A1N7IQA4
names: Similarity
messages: Belongs to the TrpF family.

714067:GXN75 RS17330
gene id: 714067:GXN75_RS17330
uniprot id: A0A1N7JI42
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

714067:GXN75 RS06340
gene id: 714067:GXN75_RS06340
uniprot id: A0A1N7MLL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

714067:GXN75 RS16575
gene id: 714067:GXN75_RS16575
uniprot id: A0A1N7JSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01835
gene id: 714067:GXN75_RS01835
uniprot id: A0A1N7P4V1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

714067:GXN75 RS04935
gene id: 714067:GXN75_RS04935
uniprot id: A0A1N7LDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10990
gene id: 714067:GXN75_RS10990
uniprot id: A0A1N7J3T8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16965
gene id: 714067:GXN75_RS16965
uniprot id: A0A1N7JLH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

714067:GXN75 RS01615
gene id: 714067:GXN75_RS01615
uniprot id: A0A1N7P7M2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

714067:GXN75 RS15235
gene id: 714067:GXN75_RS15235
uniprot id: A0A1N7PMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02760
gene id: 714067:GXN75_RS02760
uniprot id: A0A1N7NL67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16535
gene id: 714067:GXN75_RS16535
uniprot id: A0A1N7JSY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

714067:GXN75 RS12715
gene id: 714067:GXN75_RS12715
uniprot id: A0A1N7KWF7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

714067:GXN75 RS12280
gene id: 714067:GXN75_RS12280
uniprot id: A0A1N7PR84
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

714067:GXN75 RS13935
gene id: 714067:GXN75_RS13935
uniprot id: A0A1N7KG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10335
gene id: 714067:GXN75_RS10335
uniprot id: A0A1N7IZU1
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

714067:GXN75 RS00485
gene id: 714067:GXN75_RS00485
uniprot id: A0A1N7JET9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

714067:GXN75 RS07885
gene id: 714067:GXN75_RS07885
uniprot id: A0A1N7ILC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

714067:GXN75 RS05700
gene id: 714067:GXN75_RS05700
uniprot id: A0A1N7MEU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

714067:GXN75 RS04470
gene id: 714067:GXN75_RS04470
uniprot id: A0A1N7LJF6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

714067:GXN75 RS14630
gene id: 714067:GXN75_RS14630
uniprot id: A0A1N7NA21
names: Subcellular Location Annotation
messages: Cell membrane

714067:GXN75 RS17085
gene id: 714067:GXN75_RS17085
uniprot id: A0A1N7JK46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS04805
gene id: 714067:GXN75_RS04805
uniprot id: A0A1N7LFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS16315
gene id: 714067:GXN75_RS16315
uniprot id: A0A1N7JWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

714067:GXN75 RS15010
gene id: 714067:GXN75_RS15010
uniprot id: A0A1N7Q691
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

714067:GXN75 RS16480
gene id: 714067:GXN75_RS16480
uniprot id: A0A1N7JTY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

714067:GXN75 RS10255
gene id: 714067:GXN75_RS10255
uniprot id: A0A1N7IZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

714067:GXN75 RS15440
gene id: 714067:GXN75_RS15440
uniprot id: A0A1N7PKX7
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS07400
gene id: 714067:GXN75_RS07400
uniprot id: A0A1N7M537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06130
gene id: 714067:GXN75_RS06130
uniprot id: A0A1N7MJ72
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

714067:GXN75 RS15540
gene id: 714067:GXN75_RS15540
uniprot id: A0A1N7PK06
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS06930
gene id: 714067:GXN75_RS06930
uniprot id: A0A1N7M042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS13505
gene id: 714067:GXN75_RS13505
uniprot id: A0A1N7KL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS13280
gene id: 714067:GXN75_RS13280
uniprot id: A0A1N7KP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS15280
gene id: 714067:GXN75_RS15280
uniprot id: A0A1N7PM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06430
gene id: 714067:GXN75_RS06430
uniprot id: A0A1N7LV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

714067:GXN75 RS12440
gene id: 714067:GXN75_RS12440
uniprot id: A0A1N7KZQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

714067:GXN75 RS08300
gene id: 714067:GXN75_RS08300
uniprot id: A0A1N7IN82
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

714067:GXN75 RS15750
gene id: 714067:GXN75_RS15750
uniprot id: A0A1N7PEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

714067:GXN75 RS14745
gene id: 714067:GXN75_RS14745
uniprot id: A0A1N7N8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

714067:GXN75 RS01145
gene id: 714067:GXN75_RS01145
uniprot id: A0A1N7MYI2
names: Similarity
messages: Belongs to the ycf81 family.

714067:GXN75 RS09015
gene id: 714067:GXN75_RS09015
uniprot id: A0A1N7IRP8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

714067:GXN75 RS06790
gene id: 714067:GXN75_RS06790
uniprot id: A0A1N7LYQ0
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS11170
gene id: 714067:GXN75_RS11170
uniprot id: A0A1N7J4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

714067:GXN75 RS09195
gene id: 714067:GXN75_RS09195
uniprot id: A0A1N7ISN8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

714067:GXN75 RS14845
gene id: 714067:GXN75_RS14845
uniprot id: A0A1N7N7C6
names: Similarity
messages: Belongs to the SleB family.

714067:GXN75 RS12225
gene id: 714067:GXN75_RS12225
uniprot id: A0A1N7PS45
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

714067:GXN75 RS10315
gene id: 714067:GXN75_RS10315
uniprot id: A0A1N7IZL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS07660
gene id: 714067:GXN75_RS07660
uniprot id: A0A1N7IK43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

714067:GXN75 RS12540
gene id: 714067:GXN75_RS12540
uniprot id: A0A1N7KYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

714067:GXN75 RS13375
gene id: 714067:GXN75_RS13375
uniprot id: A0A1N7KMY3
names: Similarity
messages: Belongs to the UPF0473 family.

714067:GXN75 RS11935
gene id: 714067:GXN75_RS11935
uniprot id: A0A1N7Q2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10720
gene id: 714067:GXN75_RS10720
uniprot id: A0A1N7J218
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

714067:GXN75 RS03635
gene id: 714067:GXN75_RS03635
uniprot id: A0A1N7NTX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS12530
gene id: 714067:GXN75_RS12530
uniprot id: A0A1N7KYJ2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

714067:GXN75 RS04530
gene id: 714067:GXN75_RS04530
uniprot id: A0A1N7LIU8
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS15470
gene id: 714067:GXN75_RS15470
uniprot id: A0A1N7PKI3
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07170
gene id: 714067:GXN75_RS07170
uniprot id: A0A1N7M2W7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

714067:GXN75 RS02625
gene id: 714067:GXN75_RS02625
uniprot id: A0A1N7NJ75
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

714067:GXN75 RS09795
gene id: 714067:GXN75_RS09795
uniprot id: A0A1N7IWJ3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

714067:GXN75 RS10910
gene id: 714067:GXN75_RS10910
uniprot id: A0A1N7J3I4
names: Subcellular Location Annotation
messages: Cytoplasm

714067:GXN75 RS02520
gene id: 714067:GXN75_RS02520
uniprot id: A0A1N7NI82
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS12770
gene id: 714067:GXN75_RS12770
uniprot id: A0A1N7KW32
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

714067:GXN75 RS01825
gene id: 714067:GXN75_RS01825
uniprot id: A0A1N7P512
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

714067:GXN75 RS14285
gene id: 714067:GXN75_RS14285
uniprot id: A0A1N7ND63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06005
gene id: 714067:GXN75_RS06005
uniprot id: A0A1N7MID4
names: Similarity
messages: Belongs to the UPF0173 family.

714067:GXN75 RS13785
gene id: 714067:GXN75_RS13785
uniprot id: A0A1N7KI40
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

714067:GXN75 RS06735
gene id: 714067:GXN75_RS06735
uniprot id: A0A1N7LY89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

714067:GXN75 RS16145
gene id: 714067:GXN75_RS16145
uniprot id: A0A1N7JZF8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

714067:GXN75 RS04125
gene id: 714067:GXN75_RS04125
uniprot id: A0A1N7LMY7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

714067:GXN75 RS00955
gene id: 714067:GXN75_RS00955
uniprot id: A0A1N7MWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS11635
gene id: 714067:GXN75_RS11635
uniprot id: A0A1N7J7Q0
names: Similarity
messages: Belongs to the GSP E family.

714067:GXN75 RS12500
gene id: 714067:GXN75_RS12500
uniprot id: A0A1N7KZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

714067:GXN75 RS01175
gene id: 714067:GXN75_RS01175
uniprot id: A0A1N7MZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

714067:GXN75 RS16520
gene id: 714067:GXN75_RS16520
uniprot id: A0A1N7JT86
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

714067:GXN75 RS07140
gene id: 714067:GXN75_RS07140
uniprot id: A0A1N7M2A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

714067:GXN75 RS10465
gene id: 714067:GXN75_RS10465
uniprot id: A0A1N7J0N8
names: Similarity
messages: Belongs to the UPF0102 family.

714067:GXN75 RS17395
gene id: 714067:GXN75_RS17395
uniprot id: A0A1N7JHP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

714067:GXN75 RS07565
gene id: 714067:GXN75_RS07565
uniprot id: A0A1N7M6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

714067:GXN75 RS06670
gene id: 714067:GXN75_RS06670
uniprot id: A0A1N7LXL0
names: Similarity
messages: Belongs to the threonine aldolase family.

714067:GXN75 RS04080
gene id: 714067:GXN75_RS04080
uniprot id: A0A1N7LND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

714067:GXN75 RS01290
gene id: 714067:GXN75_RS01290
uniprot id: A0A1N7MZT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

714067:GXN75 RS10555
gene id: 714067:GXN75_RS10555
uniprot id: A0A1N7J146
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

714067:GXN75 RS13255
gene id: 714067:GXN75_RS13255
uniprot id: A0A1N7KPQ3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

714067:GXN75 RS10500
gene id: 714067:GXN75_RS10500
uniprot id: A0A1N7J0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

714067:GXN75 RS00560
gene id: 714067:GXN75_RS00560
uniprot id: A0A1N7MT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

714067:GXN75 RS16845
gene id: 714067:GXN75_RS16845
uniprot id: A0A1N7JNF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

714067:GXN75 RS07015
gene id: 714067:GXN75_RS07015
uniprot id: A0A1N7M0X8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

714067:GXN75 RS12300
gene id: 714067:GXN75_RS12300
uniprot id: A0A1N7PRH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS05150
gene id: 714067:GXN75_RS05150
uniprot id: A0A1N7LBI7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

714067:GXN75 RS07365
gene id: 714067:GXN75_RS07365
uniprot id: A0A1N7M4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

714067:GXN75 RS07545
gene id: 714067:GXN75_RS07545
uniprot id: A0A1N7M6T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

714067:GXN75 RS01305
gene id: 714067:GXN75_RS01305
uniprot id: A0A1N7N0B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

714067:GXN75 RS04330
gene id: 714067:GXN75_RS04330
uniprot id: A0A1N7LKX4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

714067:GXN75 RS08530
gene id: 714067:GXN75_RS08530
uniprot id: A0A1N7IPD2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

714067:GXN75 RS04765
gene id: 714067:GXN75_RS04765
uniprot id: A0A1N7LFR7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

714067:GXN75 RS08600
gene id: 714067:GXN75_RS08600
uniprot id: A0A1N7IPP0
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

714067:GXN75 RS07710
gene id: 714067:GXN75_RS07710
uniprot id: A0A1N7IKM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

714067:GXN75 RS08895
gene id: 714067:GXN75_RS08895
uniprot id: A0A1N7IR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

714067:GXN75 RS08230
gene id: 714067:GXN75_RS08230
uniprot id: A0A1N7IMV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

714067:GXN75 RS05465
gene id: 714067:GXN75_RS05465
uniprot id: A0A1N7L7Z3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

714067:GXN75 RS01805
gene id: 714067:GXN75_RS01805
uniprot id: A0A1N7P5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

714067:GXN75 RS00975
gene id: 714067:GXN75_RS00975
uniprot id: A0A1N7MWC3
names: Subcellular Location Annotation
messages: Secreted

714067:GXN75 RS15120
gene id: 714067:GXN75_RS15120
uniprot id: A0A1N7QA57
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

714067:GXN75 RS07340
gene id: 714067:GXN75_RS07340
uniprot id: A0A1N7M4K6
names: Similarity
messages: Belongs to the fructosamine kinase family.

714067:GXN75 RS04430
gene id: 714067:GXN75_RS04430
uniprot id: A0A1N7LJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

714067:GXN75 RS09355
gene id: 714067:GXN75_RS09355
uniprot id: A0A1N7ITS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

714067:GXN75 RS05865
gene id: 714067:GXN75_RS05865
uniprot id: A0A1N7MGV4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16270
gene id: 714067:GXN75_RS16270
uniprot id: A0A1N7JXU0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

714067:GXN75 RS03285
gene id: 714067:GXN75_RS03285
uniprot id: A0A1N7QAM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS15695
gene id: 714067:GXN75_RS15695
uniprot id: A0A1N7PFA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

714067:GXN75 RS01460
gene id: 714067:GXN75_RS01460
uniprot id: A0A1N7N1M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS15520
gene id: 714067:GXN75_RS15520
uniprot id: A0A1N7PK84
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

714067:GXN75 RS11010
gene id: 714067:GXN75_RS11010
uniprot id: A0A1N7J458
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

714067:GXN75 RS06265
gene id: 714067:GXN75_RS06265
uniprot id: A0A1N7MKY9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16595
gene id: 714067:GXN75_RS16595
uniprot id: A0A1N7JS12
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

714067:GXN75 RS13305
gene id: 714067:GXN75_RS13305
uniprot id: A0A1N7KNX8
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

714067:GXN75 RS08365
gene id: 714067:GXN75_RS08365
uniprot id: A0A1N7INK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

714067:GXN75 RS08790
gene id: 714067:GXN75_RS08790
uniprot id: A0A1N7IQI1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

714067:GXN75 RS15970
gene id: 714067:GXN75_RS15970
uniprot id: A0A1N7PCN0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

714067:GXN75 RS04960
gene id: 714067:GXN75_RS04960
uniprot id: A0A1N7LDF8
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

714067:GXN75 RS00705
gene id: 714067:GXN75_RS00705
uniprot id: A0A1N7MU49
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

714067:GXN75 RS17285
gene id: 714067:GXN75_RS17285
uniprot id: A0A1N7JID9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

714067:GXN75 RS13350
gene id: 714067:GXN75_RS13350
uniprot id: A0A1N7KNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

714067:GXN75 RS09520
gene id: 714067:GXN75_RS09520
uniprot id: A0A1N7IV06
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

714067:GXN75 RS17425
gene id: 714067:GXN75_RS17425
uniprot id: A0A1N7JHA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

714067:GXN75 RS01315
gene id: 714067:GXN75_RS01315
uniprot id: A0A1N7N039
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

714067:GXN75 RS01465
gene id: 714067:GXN75_RS01465
uniprot id: A0A1N7N1Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

714067:GXN75 RS08045
gene id: 714067:GXN75_RS08045
uniprot id: A0A1N7IM30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

714067:GXN75 RS08030
gene id: 714067:GXN75_RS08030
uniprot id: A0A1N7ILT0
names: Similarity
messages: Belongs to the TlyA family.

714067:GXN75 RS02525
gene id: 714067:GXN75_RS02525
uniprot id: A0A1N7NII8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

714067:GXN75 RS08410
gene id: 714067:GXN75_RS08410
uniprot id: A0A1N7INX9
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07150
gene id: 714067:GXN75_RS07150
uniprot id: A0A1N7M2G7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS13970
gene id: 714067:GXN75_RS13970
uniprot id: A0A1N7KFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

714067:GXN75 RS03445
gene id: 714067:GXN75_RS03445
uniprot id: A0A1N7NRK0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

714067:GXN75 RS11470
gene id: 714067:GXN75_RS11470
uniprot id: A0A1N7J6M9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

714067:GXN75 RS08040
gene id: 714067:GXN75_RS08040
uniprot id: A0A1N7ILS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS00795
gene id: 714067:GXN75_RS00795
uniprot id: A0A1N7MUZ8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

714067:GXN75 RS00525
gene id: 714067:GXN75_RS00525
uniprot id: A0A1N7MS00
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

714067:GXN75 RS01345
gene id: 714067:GXN75_RS01345
uniprot id: A0A1N7N0G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

714067:GXN75 RS10390
gene id: 714067:GXN75_RS10390
uniprot id: A0A1N7IZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS05855
gene id: 714067:GXN75_RS05855
uniprot id: A0A1N7MGK0
names: Similarity
messages: Belongs to the archaeal-type GPI family.

714067:GXN75 RS07560
gene id: 714067:GXN75_RS07560
uniprot id: A0A1N7M720
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

714067:GXN75 RS01435
gene id: 714067:GXN75_RS01435
uniprot id: A0A1N7N1I3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

714067:GXN75 RS14750
gene id: 714067:GXN75_RS14750
uniprot id: A0A1N7N8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

714067:GXN75 RS11185
gene id: 714067:GXN75_RS11185
uniprot id: A0A1N7J4Y0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS11580
gene id: 714067:GXN75_RS11580
uniprot id: A0A1N7J7A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

714067:GXN75 RS06220
gene id: 714067:GXN75_RS06220
uniprot id: A0A1N7MKM7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

714067:GXN75 RS12735
gene id: 714067:GXN75_RS12735
uniprot id: A0A1N7KVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

714067:GXN75 RS00730
gene id: 714067:GXN75_RS00730
uniprot id: A0A1N7MUQ9
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08025
gene id: 714067:GXN75_RS08025
uniprot id: A0A1N7ILR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

714067:GXN75 RS15275
gene id: 714067:GXN75_RS15275
uniprot id: A0A1N7PMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

714067:GXN75 RS13145
gene id: 714067:GXN75_RS13145
uniprot id: A0A1N7KQL7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

714067:GXN75 RS07205
gene id: 714067:GXN75_RS07205
uniprot id: A0A1N7M318
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

714067:GXN75 RS13380
gene id: 714067:GXN75_RS13380
uniprot id: A0A1N7KMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

714067:GXN75 RS03630
gene id: 714067:GXN75_RS03630
uniprot id: A0A1N7NU48
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

714067:GXN75 RS16870
gene id: 714067:GXN75_RS16870
uniprot id: A0A1N7JMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

714067:GXN75 RS08335
gene id: 714067:GXN75_RS08335
uniprot id: A0A1N7INN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

714067:GXN75 RS16210
gene id: 714067:GXN75_RS16210
uniprot id: A0A1N7JYE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

714067:GXN75 RS01675
gene id: 714067:GXN75_RS01675
uniprot id: A0A1N7P6X9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

714067:GXN75 RS15260
gene id: 714067:GXN75_RS15260
uniprot id: A0A1N7PMM0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

714067:GXN75 RS14800
gene id: 714067:GXN75_RS14800
uniprot id: A0A1N7N864
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

714067:GXN75 RS15905
gene id: 714067:GXN75_RS15905
uniprot id: A0A1N7PDB7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

714067:GXN75 RS13595
gene id: 714067:GXN75_RS13595
uniprot id: A0A1N7KK71
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

714067:GXN75 RS16895
gene id: 714067:GXN75_RS16895
uniprot id: A0A1N7JMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

714067:GXN75 RS08820
gene id: 714067:GXN75_RS08820
uniprot id: A0A1N7IQP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

714067:GXN75 RS14445
gene id: 714067:GXN75_RS14445
uniprot id: A0A1N7NBM0
names: Similarity
messages: Belongs to the glutamate synthase family.

714067:GXN75 RS10030
gene id: 714067:GXN75_RS10030
uniprot id: A0A1N7IY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

714067:GXN75 RS05225
gene id: 714067:GXN75_RS05225
uniprot id: A0A1N7LAG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

714067:GXN75 RS11920
gene id: 714067:GXN75_RS11920
uniprot id: A0A1N7Q3K1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

714067:GXN75 RS04780
gene id: 714067:GXN75_RS04780
uniprot id: A0A1N7LFK2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS02785
gene id: 714067:GXN75_RS02785
uniprot id: A0A1N7NL02
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

714067:GXN75 RS13090
gene id: 714067:GXN75_RS13090
uniprot id: A0A1N7KR93
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

714067:GXN75 RS16515
gene id: 714067:GXN75_RS16515
uniprot id: A0A1N7JTC7
names: Similarity
messages: Belongs to the CarA family.

714067:GXN75 RS17060
gene id: 714067:GXN75_RS17060
uniprot id: A0A1N7JKA2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS10860
gene id: 714067:GXN75_RS10860
uniprot id: A0A1N7J348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08195
gene id: 714067:GXN75_RS08195
uniprot id: A0A1N7IMM9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

714067:GXN75 RS07245
gene id: 714067:GXN75_RS07245
uniprot id: A0A1N7M3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

714067:GXN75 RS06165
gene id: 714067:GXN75_RS06165
uniprot id: A0A1N7MJI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

714067:GXN75 RS09605
gene id: 714067:GXN75_RS09605
uniprot id: A0A1N7IVG4
names: Similarity
messages: Belongs to the ribF family.

714067:GXN75 RS03690
gene id: 714067:GXN75_RS03690
uniprot id: A0A1N7NUQ8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS09315
gene id: 714067:GXN75_RS09315
uniprot id: A0A1N7ITC9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

714067:GXN75 RS03480
gene id: 714067:GXN75_RS03480
uniprot id: A0A1N7NRP3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06450
gene id: 714067:GXN75_RS06450
uniprot id: A0A1N7LV36
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

714067:GXN75 RS01380
gene id: 714067:GXN75_RS01380
uniprot id: A0A1N7N0U8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

714067:GXN75 RS05930
gene id: 714067:GXN75_RS05930
uniprot id: A0A1N7MH75
names: PTM
messages: Binds 1 heme c group covalently per subunit.

714067:GXN75 RS01260
gene id: 714067:GXN75_RS01260
uniprot id: A0A1N7MZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

714067:GXN75 RS02855
gene id: 714067:GXN75_RS02855
uniprot id: A0A1N7NM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

714067:GXN75 RS02135
gene id: 714067:GXN75_RS02135
uniprot id: A0A1N7P146
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

714067:GXN75 RS13195
gene id: 714067:GXN75_RS13195
uniprot id: A0A1N7KPY7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08360
gene id: 714067:GXN75_RS08360
uniprot id: A0A1N7INL3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

714067:GXN75 RS11505
gene id: 714067:GXN75_RS11505
uniprot id: A0A1N7J6Q5
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

714067:GXN75 RS01700
gene id: 714067:GXN75_RS01700
uniprot id: A0A1N7P6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

714067:GXN75 RS06435
gene id: 714067:GXN75_RS06435
uniprot id: A0A1N7LUV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

714067:GXN75 RS10365
gene id: 714067:GXN75_RS10365
uniprot id: A0A1N7IZW6
names: Similarity
messages: Belongs to the PdxA family. PdxA2 subfamily.

714067:GXN75 RS17200
gene id: 714067:GXN75_RS17200
uniprot id: A0A1N7JIT7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

714067:GXN75 RS09455
gene id: 714067:GXN75_RS09455
uniprot id: A0A1N7IUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

714067:GXN75 RS10080
gene id: 714067:GXN75_RS10080
uniprot id: A0A1N7IYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06905
gene id: 714067:GXN75_RS06905
uniprot id: A0A1N7M071
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

714067:GXN75 RS02510
gene id: 714067:GXN75_RS02510
uniprot id: A0A1N7NIB8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

714067:GXN75 RS09915
gene id: 714067:GXN75_RS09915
uniprot id: A0A1N7IXE6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS11130
gene id: 714067:GXN75_RS11130
uniprot id: A0A1N7J4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

714067:GXN75 RS00550
gene id: 714067:GXN75_RS00550
uniprot id: A0A1N7MSG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

714067:GXN75 RS14435
gene id: 714067:GXN75_RS14435
uniprot id: A0A1N7NBQ5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

714067:GXN75 RS02870
gene id: 714067:GXN75_RS02870
uniprot id: A0A1N7NMK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

714067:GXN75 RS07030
gene id: 714067:GXN75_RS07030
uniprot id: A0A1N7M139
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

714067:GXN75 RS00945
gene id: 714067:GXN75_RS00945
uniprot id: A0A1N7MW70
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS05445
gene id: 714067:GXN75_RS05445
uniprot id: A0A1N7L7P5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

714067:GXN75 RS12035
gene id: 714067:GXN75_RS12035
uniprot id: A0A1N7Q2G0
names: Similarity
messages: Belongs to the GerABKA family.

714067:GXN75 RS13495
gene id: 714067:GXN75_RS13495
uniprot id: A0A1N7KLH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS01110
gene id: 714067:GXN75_RS01110
uniprot id: A0A1N7MYA3
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

714067:GXN75 RS01370
gene id: 714067:GXN75_RS01370
uniprot id: A0A1N7N0P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

714067:GXN75 RS13765
gene id: 714067:GXN75_RS13765
uniprot id: A0A1N7KI78
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

714067:GXN75 RS08140
gene id: 714067:GXN75_RS08140
uniprot id: A0A1N7IMK7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS08170
gene id: 714067:GXN75_RS08170
uniprot id: A0A1N7IMH2
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS09690
gene id: 714067:GXN75_RS09690
uniprot id: A0A1N7IVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

714067:GXN75 RS09710
gene id: 714067:GXN75_RS09710
uniprot id: A0A1N7IW15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

714067:GXN75 RS16215
gene id: 714067:GXN75_RS16215
uniprot id: A0A1N7JYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

714067:GXN75 RS05175
gene id: 714067:GXN75_RS05175
uniprot id: A0A1N7LB95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS13600
gene id: 714067:GXN75_RS13600
uniprot id: A0A1N7KK18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS12630
gene id: 714067:GXN75_RS12630
uniprot id: A0A1N7KXF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

714067:GXN75 RS01900
gene id: 714067:GXN75_RS01900
uniprot id: A0A1N7P474
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS12675
gene id: 714067:GXN75_RS12675
uniprot id: A0A1N7KX10
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS03195
gene id: 714067:GXN75_RS03195
uniprot id: A0A1N7Q0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

714067:GXN75 RS15160
gene id: 714067:GXN75_RS15160
uniprot id: A0A1N7Q9P0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

714067:GXN75 RS11905
gene id: 714067:GXN75_RS11905
uniprot id: A0A1N7Q2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

714067:GXN75 RS17005
gene id: 714067:GXN75_RS17005
uniprot id: A0A1N7JL73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

714067:GXN75 RS05545
gene id: 714067:GXN75_RS05545
uniprot id: A0A1N7MDC4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

714067:GXN75 RS03685
gene id: 714067:GXN75_RS03685
uniprot id: A0A1N7NUI1
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

714067:GXN75 RS01200
gene id: 714067:GXN75_RS01200
uniprot id: A0A1N7MZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

714067:GXN75 RS03590
gene id: 714067:GXN75_RS03590
uniprot id: A0A1N7NTL2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

714067:GXN75 RS04980
gene id: 714067:GXN75_RS04980
uniprot id: A0A1N7LD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01300
gene id: 714067:GXN75_RS01300
uniprot id: A0A1N7N0I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

714067:GXN75 RS08645
gene id: 714067:GXN75_RS08645
uniprot id: A0A1N7IPY7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

714067:GXN75 RS09550
gene id: 714067:GXN75_RS09550
uniprot id: A0A1N7IV75
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

714067:GXN75 RS05205
gene id: 714067:GXN75_RS05205
uniprot id: A0A1N7LAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

714067:GXN75 RS10780
gene id: 714067:GXN75_RS10780
uniprot id: A0A1N7J2I7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

714067:GXN75 RS14110
gene id: 714067:GXN75_RS14110
uniprot id: A0A1N7KDN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

714067:GXN75 RS16260
gene id: 714067:GXN75_RS16260
uniprot id: A0A1N7JXK9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

714067:GXN75 RS06290
gene id: 714067:GXN75_RS06290
uniprot id: A0A1N7MKY7
names: Similarity
messages: Belongs to the citrate synthase family.

714067:GXN75 RS00785
gene id: 714067:GXN75_RS00785
uniprot id: A0A1N7MUJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

714067:GXN75 RS04605
gene id: 714067:GXN75_RS04605
uniprot id: A0A1N7LHV0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

714067:GXN75 RS06210
gene id: 714067:GXN75_RS06210
uniprot id: A0A1N7MK16
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS04675
gene id: 714067:GXN75_RS04675
uniprot id: A0A1N7LGW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS08210
gene id: 714067:GXN75_RS08210
uniprot id: A0A1N7IMY7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

714067:GXN75 RS12445
gene id: 714067:GXN75_RS12445
uniprot id: A0A1N7KZT2
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13020
gene id: 714067:GXN75_RS13020
uniprot id: A0A1N7KSQ3
names: Similarity
messages: Belongs to the peptidase S66 family.

714067:GXN75 RS02475
gene id: 714067:GXN75_RS02475
uniprot id: A0A1N7NID7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

714067:GXN75 RS13895
gene id: 714067:GXN75_RS13895
uniprot id: A0A1N7KGW3
names: Similarity
messages: Belongs to the peptidase S8 family.

714067:GXN75 RS10965
gene id: 714067:GXN75_RS10965
uniprot id: A0A1N7J3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08750
gene id: 714067:GXN75_RS08750
uniprot id: A0A1N7IQE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

714067:GXN75 RS16650
gene id: 714067:GXN75_RS16650
uniprot id: A0A1N7JQZ9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

714067:GXN75 RS11315
gene id: 714067:GXN75_RS11315
uniprot id: A0A1N7J5J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS03215
gene id: 714067:GXN75_RS03215
uniprot id: A0A1N7Q0B0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

714067:GXN75 RS07125
gene id: 714067:GXN75_RS07125
uniprot id: A0A1N7M250
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS11100
gene id: 714067:GXN75_RS11100
uniprot id: A0A1N7J4F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

714067:GXN75 RS07575
gene id: 714067:GXN75_RS07575
uniprot id: A0A1N7M727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS14620
gene id: 714067:GXN75_RS14620
uniprot id: A0A1N7N9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08165
gene id: 714067:GXN75_RS08165
uniprot id: A0A1N7IMG2
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS07770
gene id: 714067:GXN75_RS07770
uniprot id: A0A1N7IKJ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

714067:GXN75 RS11845
gene id: 714067:GXN75_RS11845
uniprot id: A0A1N7Q4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

714067:GXN75 RS01405
gene id: 714067:GXN75_RS01405
uniprot id: A0A1N7N107
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

714067:GXN75 RS06390
gene id: 714067:GXN75_RS06390
uniprot id: A0A1N7MMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

714067:GXN75 RS08490
gene id: 714067:GXN75_RS08490
uniprot id: A0A1N7IP61
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

714067:GXN75 RS14335
gene id: 714067:GXN75_RS14335
uniprot id: A0A1N7NCU3
names: Similarity
messages: Belongs to the histone deacetylase family.

714067:GXN75 RS08155
gene id: 714067:GXN75_RS08155
uniprot id: A0A1N7IME3
names: Similarity
messages: Belongs to the ribulokinase family.

714067:GXN75 RS05945
gene id: 714067:GXN75_RS05945
uniprot id: A0A1N7MHW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16205
gene id: 714067:GXN75_RS16205
uniprot id: A0A1N7JYI1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

714067:GXN75 RS00030
gene id: 714067:GXN75_RS00030
uniprot id: A0A1N7JH44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

714067:GXN75 RS06135
gene id: 714067:GXN75_RS06135
uniprot id: A0A1N7MJT6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

714067:GXN75 RS01400
gene id: 714067:GXN75_RS01400
uniprot id: A0A1N7N1B9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS01365
gene id: 714067:GXN75_RS01365
uniprot id: A0A1N7N0X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

714067:GXN75 RS01220
gene id: 714067:GXN75_RS01220
uniprot id: A0A1N7MZ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

714067:GXN75 RS06780
gene id: 714067:GXN75_RS06780
uniprot id: A0A1N7LYP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

714067:GXN75 RS10495
gene id: 714067:GXN75_RS10495
uniprot id: A0A1N7J0V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

714067:GXN75 RS12670
gene id: 714067:GXN75_RS12670
uniprot id: A0A1N7KX08
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS17280
gene id: 714067:GXN75_RS17280
uniprot id: A0A1N7JI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

714067:GXN75 RS09000
gene id: 714067:GXN75_RS09000
uniprot id: A0A1N7IRT1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

714067:GXN75 RS13485
gene id: 714067:GXN75_RS13485
uniprot id: A0A1N7KLW1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

714067:GXN75 RS06510
gene id: 714067:GXN75_RS06510
uniprot id: A0A1N7LVU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

714067:GXN75 RS01115
gene id: 714067:GXN75_RS01115
uniprot id: A0A1N7MYG8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

714067:GXN75 RS16300
gene id: 714067:GXN75_RS16300
uniprot id: A0A1N7JWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

714067:GXN75 RS10685
gene id: 714067:GXN75_RS10685
uniprot id: A0A1N7J1L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

714067:GXN75 RS12645
gene id: 714067:GXN75_RS12645
uniprot id: A0A1N7KX79
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13215
gene id: 714067:GXN75_RS13215
uniprot id: A0A1N7KPR9
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS01055
gene id: 714067:GXN75_RS01055
uniprot id: A0A1N7MY56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS01265
gene id: 714067:GXN75_RS01265
uniprot id: A0A1N7MZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

714067:GXN75 RS09745
gene id: 714067:GXN75_RS09745
uniprot id: A0A1N7IWA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

714067:GXN75 RS08010
gene id: 714067:GXN75_RS08010
uniprot id: A0A1N7ILP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

714067:GXN75 RS13285
gene id: 714067:GXN75_RS13285
uniprot id: A0A1N7KNZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00585
gene id: 714067:GXN75_RS00585
uniprot id: A0A1N7MST4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS04400
gene id: 714067:GXN75_RS04400
uniprot id: A0A1N7LK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

714067:GXN75 RS04575
gene id: 714067:GXN75_RS04575
uniprot id: A0A1N7LIB6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

714067:GXN75 RS06845
gene id: 714067:GXN75_RS06845
uniprot id: A0A1N7LZC0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

714067:GXN75 RS11695
gene id: 714067:GXN75_RS11695
uniprot id: A0A1N7Q8P1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

714067:GXN75 RS03775
gene id: 714067:GXN75_RS03775
uniprot id: A0A1N7NW37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

714067:GXN75 RS16200
gene id: 714067:GXN75_RS16200
uniprot id: A0A1N7JYM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS16440
gene id: 714067:GXN75_RS16440
uniprot id: A0A1N7JUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

714067:GXN75 RS16780
gene id: 714067:GXN75_RS16780
uniprot id: A0A1N7JP50
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

714067:GXN75 RS11160
gene id: 714067:GXN75_RS11160
uniprot id: A0A1N7J4M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS07825
gene id: 714067:GXN75_RS07825
uniprot id: A0A1N7IKU3
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

714067:GXN75 RS16900
gene id: 714067:GXN75_RS16900
uniprot id: A0A1N7JMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

714067:GXN75 RS03100
gene id: 714067:GXN75_RS03100
uniprot id: A0A1N7PZT4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS12470
gene id: 714067:GXN75_RS12470
uniprot id: A0A1N7KZL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02070
gene id: 714067:GXN75_RS02070
uniprot id: A0A1N7P2Q9
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

714067:GXN75 RS05800
gene id: 714067:GXN75_RS05800
uniprot id: A0A1N7MFY0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

714067:GXN75 RS15140
gene id: 714067:GXN75_RS15140
uniprot id: A0A1N7Q9J2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

714067:GXN75 RS02580
gene id: 714067:GXN75_RS02580
uniprot id: A0A1N7NJ20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS16920
gene id: 714067:GXN75_RS16920
uniprot id: A0A1N7JM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

714067:GXN75 RS05415
gene id: 714067:GXN75_RS05415
uniprot id: A0A1N7L851
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

714067:GXN75 RS16340
gene id: 714067:GXN75_RS16340
uniprot id: A0A1N7JWJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Monomer.

714067:GXN75 RS15775
gene id: 714067:GXN75_RS15775
uniprot id: A0A1N7PEK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

714067:GXN75 RS11975
gene id: 714067:GXN75_RS11975
uniprot id: A0A1N7Q2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS12340
gene id: 714067:GXN75_RS12340
uniprot id: A0A1N7PQS4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

714067:GXN75 RS12940
gene id: 714067:GXN75_RS12940
uniprot id: A0A1N7KTI3
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

714067:GXN75 RS08980
gene id: 714067:GXN75_RS08980
uniprot id: A0A1N7IRH6
names: Similarity
messages: Belongs to the FGGY kinase family.

714067:GXN75 RS13450
gene id: 714067:GXN75_RS13450
uniprot id: A0A1N7KM74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

714067:GXN75 RS07225
gene id: 714067:GXN75_RS07225
uniprot id: A0A1N7M385
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

714067:GXN75 RS12255
gene id: 714067:GXN75_RS12255
uniprot id: A0A1N7PRG6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

714067:GXN75 RS03595
gene id: 714067:GXN75_RS03595
uniprot id: A0A1N7NTP4
names: Similarity
messages: Belongs to the GerABKA family.
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

714067:GXN75 RS11630
gene id: 714067:GXN75_RS11630
uniprot id: A0A1N7J7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

714067:GXN75 RS07175
gene id: 714067:GXN75_RS07175
uniprot id: A0A1N7M2M4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

714067:GXN75 RS16770
gene id: 714067:GXN75_RS16770
uniprot id: A0A1N7JPI4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

714067:GXN75 RS12775
gene id: 714067:GXN75_RS12775
uniprot id: A0A1N7KVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

714067:GXN75 RS01100
gene id: 714067:GXN75_RS01100
uniprot id: A0A1N7MY20
names: Similarity
messages: Belongs to the CtsR family.

714067:GXN75 RS05300
gene id: 714067:GXN75_RS05300
uniprot id: A0A1N7L9R3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

714067:GXN75 RS09540
gene id: 714067:GXN75_RS09540
uniprot id: A0A1N7IUW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

714067:GXN75 RS04325
gene id: 714067:GXN75_RS04325
uniprot id: A0A1N7LKV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS05530
gene id: 714067:GXN75_RS05530
uniprot id: A0A1N7MD63
names: Subunit
messages: Monomer.

714067:GXN75 RS01225
gene id: 714067:GXN75_RS01225
uniprot id: A0A1N7MZ85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

714067:GXN75 RS01375
gene id: 714067:GXN75_RS01375
uniprot id: A0A1N7N0W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

714067:GXN75 RS17145
gene id: 714067:GXN75_RS17145
uniprot id: A0A1N7JJN3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

714067:GXN75 RS14300
gene id: 714067:GXN75_RS14300
uniprot id: A0A1N7NDC3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS08555
gene id: 714067:GXN75_RS08555
uniprot id: A0A1N7IPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

714067:GXN75 RS10010
gene id: 714067:GXN75_RS10010
uniprot id: A0A1N7IXY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS16715
gene id: 714067:GXN75_RS16715
uniprot id: A0A1N7JQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

714067:GXN75 RS04310
gene id: 714067:GXN75_RS04310
uniprot id: A0A1N7LL36
names: Similarity
messages: Belongs to the phosphopentomutase family.

714067:GXN75 RS15245
gene id: 714067:GXN75_RS15245
uniprot id: A0A1N7PMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS03760
gene id: 714067:GXN75_RS03760
uniprot id: A0A1N7NVP9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

714067:GXN75 RS11215
gene id: 714067:GXN75_RS11215
uniprot id: A0A1N7J4Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

714067:GXN75 RS13700
gene id: 714067:GXN75_RS13700
uniprot id: A0A1N7KJI9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

714067:GXN75 RS14640
gene id: 714067:GXN75_RS14640
uniprot id: A0A1N7N9M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

714067:GXN75 RS10870
gene id: 714067:GXN75_RS10870
uniprot id: A0A1N7J2Z0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

714067:GXN75 RS04045
gene id: 714067:GXN75_RS04045
uniprot id: A0A1N7LNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08150
gene id: 714067:GXN75_RS08150
uniprot id: A0A1N7IMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

714067:GXN75 RS11415
gene id: 714067:GXN75_RS11415
uniprot id: A0A1N7J6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS06285
gene id: 714067:GXN75_RS06285
uniprot id: A0A1N7ML64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

714067:GXN75 RS12475
gene id: 714067:GXN75_RS12475
uniprot id: A0A1N7KZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

714067:GXN75 RS16245
gene id: 714067:GXN75_RS16245
uniprot id: A0A1N7JXX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

714067:GXN75 RS09925
gene id: 714067:GXN75_RS09925
uniprot id: A0A1N7IXH5
names: Similarity
messages: Belongs to the EamA transporter family.

714067:GXN75 RS06045
gene id: 714067:GXN75_RS06045
uniprot id: A0A1N7MIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS07305
gene id: 714067:GXN75_RS07305
uniprot id: A0A1N7M4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS02755
gene id: 714067:GXN75_RS02755
uniprot id: A0A1N7NKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

714067:GXN75 RS15225
gene id: 714067:GXN75_RS15225
uniprot id: A0A1N7PMV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

714067:GXN75 RS15845
gene id: 714067:GXN75_RS15845
uniprot id: A0A1N7PDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

714067:GXN75 RS03175
gene id: 714067:GXN75_RS03175
uniprot id: A0A1N7PZY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16960
gene id: 714067:GXN75_RS16960
uniprot id: A0A1N7JLR9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

714067:GXN75 RS17035
gene id: 714067:GXN75_RS17035
uniprot id: A0A1N7JKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

714067:GXN75 RS16220
gene id: 714067:GXN75_RS16220
uniprot id: A0A1N7JYA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS15230
gene id: 714067:GXN75_RS15230
uniprot id: A0A1N7PMP7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

714067:GXN75 RS11400
gene id: 714067:GXN75_RS11400
uniprot id: A0A1N7J6B7
names: Similarity
messages: Belongs to the UPF0637 family.

714067:GXN75 RS06720
gene id: 714067:GXN75_RS06720
uniprot id: A0A1N7LY86
names: Similarity
messages: Belongs to the peptidase C56 family.

714067:GXN75 RS10835
gene id: 714067:GXN75_RS10835
uniprot id: A0A1N7J2P5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

714067:GXN75 RS17320
gene id: 714067:GXN75_RS17320
uniprot id: A0A1N7JI13
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

714067:GXN75 RS06970
gene id: 714067:GXN75_RS06970
uniprot id: A0A1N7M0Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

714067:GXN75 RS16955
gene id: 714067:GXN75_RS16955
uniprot id: A0A1N7JLP4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

714067:GXN75 RS07535
gene id: 714067:GXN75_RS07535
uniprot id: A0A1N7M6N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

714067:GXN75 RS05785
gene id: 714067:GXN75_RS05785
uniprot id: A0A1N7MFS6
names: Similarity
messages: Belongs to the FGGY kinase family.

714067:GXN75 RS01450
gene id: 714067:GXN75_RS01450
uniprot id: A0A1N7N1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

714067:GXN75 RS08260
gene id: 714067:GXN75_RS08260
uniprot id: A0A1N7IN05
names: Similarity
messages: Belongs to the Fur family.

714067:GXN75 RS08685
gene id: 714067:GXN75_RS08685
uniprot id: A0A1N7IQB0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

714067:GXN75 RS13735
gene id: 714067:GXN75_RS13735
uniprot id: A0A1N7KIS4
names: Similarity
messages: Belongs to the peptidase S8 family.

714067:GXN75 RS09880
gene id: 714067:GXN75_RS09880
uniprot id: A0A1N7IX76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

714067:GXN75 RS05340
gene id: 714067:GXN75_RS05340
uniprot id: A0A1N7L911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS12140
gene id: 714067:GXN75_RS12140
uniprot id: A0A1N7PSR1
names: Subcellular Location Annotation
messages: Cytoplasm

714067:GXN75 RS16925
gene id: 714067:GXN75_RS16925
uniprot id: A0A1N7JM57
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS03825
gene id: 714067:GXN75_RS03825
uniprot id: A0A1N7NWB9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

714067:GXN75 RS14700
gene id: 714067:GXN75_RS14700
uniprot id: A0A1N7N998
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS09515
gene id: 714067:GXN75_RS09515
uniprot id: A0A1N7IUZ5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

714067:GXN75 RS11190
gene id: 714067:GXN75_RS11190
uniprot id: A0A1N7J4T7
names: Similarity
messages: Belongs to the transpeptidase family.

714067:GXN75 RS09080
gene id: 714067:GXN75_RS09080
uniprot id: A0A1N7IS34
names: Similarity
messages: Belongs to the transposase 7 family.

714067:GXN75 RS04650
gene id: 714067:GXN75_RS04650
uniprot id: A0A1N7LH91
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

714067:GXN75 RS06760
gene id: 714067:GXN75_RS06760
uniprot id: A0A1N7LYI3
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

714067:GXN75 RS08265
gene id: 714067:GXN75_RS08265
uniprot id: A0A1N7INA3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

714067:GXN75 RS08345
gene id: 714067:GXN75_RS08345
uniprot id: A0A1N7INI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

714067:GXN75 RS15795
gene id: 714067:GXN75_RS15795
uniprot id: A0A1N7PE99
names: Similarity
messages: Belongs to the phosphohexose mutase family.

714067:GXN75 RS01620
gene id: 714067:GXN75_RS01620
uniprot id: A0A1N7P7K9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS09895
gene id: 714067:GXN75_RS09895
uniprot id: A0A1N7IXA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

714067:GXN75 RS12305
gene id: 714067:GXN75_RS12305
uniprot id: A0A1N7PQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

714067:GXN75 RS01625
gene id: 714067:GXN75_RS01625
uniprot id: A0A1N7P7H7
names: Similarity
messages: Belongs to the AHA1 family.

714067:GXN75 RS02715
gene id: 714067:GXN75_RS02715
uniprot id: A0A1N7NKE3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

714067:GXN75 RS16640
gene id: 714067:GXN75_RS16640
uniprot id: A0A1N7JR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS14850
gene id: 714067:GXN75_RS14850
uniprot id: A0A1N7N7S3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

714067:GXN75 RS10370
gene id: 714067:GXN75_RS10370
uniprot id: A0A1N7IZX6
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

714067:GXN75 RS16330
gene id: 714067:GXN75_RS16330
uniprot id: A0A1N7JWD3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

714067:GXN75 RS12135
gene id: 714067:GXN75_RS12135
uniprot id: A0A1N7PSW0
names: Similarity
messages: Belongs to the peptidase S13 family.

714067:GXN75 RS12315
gene id: 714067:GXN75_RS12315
uniprot id: A0A1N7PQQ6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

714067:GXN75 RS09260
gene id: 714067:GXN75_RS09260
uniprot id: A0A1N7ITD1
names: Similarity
messages: Belongs to the glutamine synthetase family.

714067:GXN75 RS00010
gene id: 714067:GXN75_RS00010
uniprot id: A0A1N7JHB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

714067:GXN75 RS00800
gene id: 714067:GXN75_RS00800
uniprot id: A0A1N7MVB7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

714067:GXN75 RS07800
gene id: 714067:GXN75_RS07800
uniprot id: A0A1N7IKN9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

714067:GXN75 RS13365
gene id: 714067:GXN75_RS13365
uniprot id: A0A1N7KMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

714067:GXN75 RS02155
gene id: 714067:GXN75_RS02155
uniprot id: A0A1N7P0Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

714067:GXN75 RS01800
gene id: 714067:GXN75_RS01800
uniprot id: A0A1N7P5C6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS13720
gene id: 714067:GXN75_RS13720
uniprot id: A0A1N7KJA0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

714067:GXN75 RS12515
gene id: 714067:GXN75_RS12515
uniprot id: A0A1N7KYN4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

714067:GXN75 RS15215
gene id: 714067:GXN75_RS15215
uniprot id: A0A1N7PNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS03770
gene id: 714067:GXN75_RS03770
uniprot id: A0A1N7NVP6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

714067:GXN75 RS08120
gene id: 714067:GXN75_RS08120
uniprot id: A0A1N7IM85
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

714067:GXN75 RS09740
gene id: 714067:GXN75_RS09740
uniprot id: A0A1N7IWC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

714067:GXN75 RS17090
gene id: 714067:GXN75_RS17090
uniprot id: A0A1N7JK26
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

714067:GXN75 RS07345
gene id: 714067:GXN75_RS07345
uniprot id: A0A1N7M4K4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

714067:GXN75 RS06320
gene id: 714067:GXN75_RS06320
uniprot id: A0A1N7MLL0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

714067:GXN75 RS09970
gene id: 714067:GXN75_RS09970
uniprot id: A0A1N7IXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS08810
gene id: 714067:GXN75_RS08810
uniprot id: A0A1N7IQP2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

714067:GXN75 RS13010
gene id: 714067:GXN75_RS13010
uniprot id: A0A1N7KSJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

714067:GXN75 RS15815
gene id: 714067:GXN75_RS15815
uniprot id: A0A1N7PE53
names: Similarity
messages: Belongs to the alkaline phosphatase family.

714067:GXN75 RS11020
gene id: 714067:GXN75_RS11020
uniprot id: A0A1N7J3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

714067:GXN75 RS02710
gene id: 714067:GXN75_RS02710
uniprot id: A0A1N7NKH3
names: Similarity
messages: Belongs to the TPP enzyme family.

714067:GXN75 RS12040
gene id: 714067:GXN75_RS12040
uniprot id: A0A1N7Q1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

714067:GXN75 RS09020
gene id: 714067:GXN75_RS09020
uniprot id: A0A1N7IRW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably oligomerizes.

714067:GXN75 RS07765
gene id: 714067:GXN75_RS07765
uniprot id: A0A1N7IKK9
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS09685
gene id: 714067:GXN75_RS09685
uniprot id: A0A1N7IVV7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS03515
gene id: 714067:GXN75_RS03515
uniprot id: A0A1N7NSL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

714067:GXN75 RS01430
gene id: 714067:GXN75_RS01430
uniprot id: A0A1N7N1B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

714067:GXN75 RS08225
gene id: 714067:GXN75_RS08225
uniprot id: A0A1N7IMU3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

714067:GXN75 RS11220
gene id: 714067:GXN75_RS11220
uniprot id: A0A1N7J5B7
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

714067:GXN75 RS03080
gene id: 714067:GXN75_RS03080
uniprot id: A0A1N7PYU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

714067:GXN75 RS15575
gene id: 714067:GXN75_RS15575
uniprot id: A0A1N7PH33
names: Cofactor
messages: Binds 1 FAD per subunit.

714067:GXN75 RS10740
gene id: 714067:GXN75_RS10740
uniprot id: A0A1N7J251
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

714067:GXN75 RS09715
gene id: 714067:GXN75_RS09715
uniprot id: A0A1N7IVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

714067:GXN75 RS11280
gene id: 714067:GXN75_RS11280
uniprot id: A0A1N7J5E6
names: Subcellular Location Annotation
messages: Mitochondrion

714067:GXN75 RS16885
gene id: 714067:GXN75_RS16885
uniprot id: A0A1N7JMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

714067:GXN75 RS01660
gene id: 714067:GXN75_RS01660
uniprot id: A0A1N7P7B0
names: Similarity
messages: Belongs to the DinB family.

714067:GXN75 RS05505
gene id: 714067:GXN75_RS05505
uniprot id: A0A1N7MCU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS00125
gene id: 714067:GXN75_RS00125
uniprot id: A0A1N7JGQ3
names: Similarity
messages: Belongs to the Fur family.

714067:GXN75 RS13260
gene id: 714067:GXN75_RS13260
uniprot id: A0A1N7KP51
names: Similarity
messages: Belongs to the GerABKA family.

714067:GXN75 RS01485
gene id: 714067:GXN75_RS01485
uniprot id: A0A1N7N2H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

714067:GXN75 RS12535
gene id: 714067:GXN75_RS12535
uniprot id: A0A1N7KYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

714067:GXN75 RS07065
gene id: 714067:GXN75_RS07065
uniprot id: A0A1N7M1K1
names: Similarity
messages: Belongs to the peptidase S16 family.

714067:GXN75 RS14500
gene id: 714067:GXN75_RS14500
uniprot id: A0A1N7NB84
names: Similarity
messages: Belongs to the peptidase M29 family.

714067:GXN75 RS10995
gene id: 714067:GXN75_RS10995
uniprot id: A0A1N7J410
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

714067:GXN75 RS06360
gene id: 714067:GXN75_RS06360
uniprot id: A0A1N7MM24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

714067:GXN75 RS16405
gene id: 714067:GXN75_RS16405
uniprot id: A0A1N7JVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

714067:GXN75 RS14310
gene id: 714067:GXN75_RS14310
uniprot id: A0A1N7NDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS16585
gene id: 714067:GXN75_RS16585
uniprot id: A0A1N7JS66
names: PTM
messages: Binds 1 heme c group covalently per subunit.

714067:GXN75 RS13860
gene id: 714067:GXN75_RS13860
uniprot id: A0A1N7KH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

714067:GXN75 RS01310
gene id: 714067:GXN75_RS01310
uniprot id: A0A1N7N009
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

714067:GXN75 RS08440
gene id: 714067:GXN75_RS08440
uniprot id: A0A1N7IP83
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

714067:GXN75 RS03165
gene id: 714067:GXN75_RS03165
uniprot id: A0A1N7PZU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

714067:GXN75 RS09160
gene id: 714067:GXN75_RS09160
uniprot id: A0A1N7ISQ6
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS17070
gene id: 714067:GXN75_RS17070
uniprot id: A0A1N7JK99
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS01255
gene id: 714067:GXN75_RS01255
uniprot id: A0A1N7N0B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

714067:GXN75 RS12000
gene id: 714067:GXN75_RS12000
uniprot id: A0A1N7Q2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

714067:GXN75 RS07915
gene id: 714067:GXN75_RS07915
uniprot id: A0A1N7ILH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS05160
gene id: 714067:GXN75_RS05160
uniprot id: A0A1N7LBC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

714067:GXN75 RS10515
gene id: 714067:GXN75_RS10515
uniprot id: A0A1N7J0Z0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

714067:GXN75 RS00680
gene id: 714067:GXN75_RS00680
uniprot id: A0A1N7MTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

714067:GXN75 RS15290
gene id: 714067:GXN75_RS15290
uniprot id: A0A1N7PMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

714067:GXN75 RS04320
gene id: 714067:GXN75_RS04320
uniprot id: A0A1N7LL44
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

714067:GXN75 RS07255
gene id: 714067:GXN75_RS07255
uniprot id: A0A1N7M3Y4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

714067:GXN75 RS13185
gene id: 714067:GXN75_RS13185
uniprot id: A0A1N7KQ55
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS13840
gene id: 714067:GXN75_RS13840
uniprot id: A0A1N7KHG2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

714067:GXN75 RS16695
gene id: 714067:GXN75_RS16695
uniprot id: A0A1N7JQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

714067:GXN75 RS08390
gene id: 714067:GXN75_RS08390
uniprot id: A0A1N7INU7
names: Similarity
messages: Belongs to the peptidase S11 family.

714067:GXN75 RS09725
gene id: 714067:GXN75_RS09725
uniprot id: A0A1N7IW34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

714067:GXN75 RS03130
gene id: 714067:GXN75_RS03130
uniprot id: A0A1N7PZJ7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

714067:GXN75 RS17100
gene id: 714067:GXN75_RS17100
uniprot id: A0A1N7JJZ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

714067:GXN75 RS10085
gene id: 714067:GXN75_RS10085
uniprot id: A0A1N7IYC1
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS15620
gene id: 714067:GXN75_RS15620
uniprot id: A0A1N7PGS9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

714067:GXN75 RS17325
gene id: 714067:GXN75_RS17325
uniprot id: A0A1N7JHY8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

714067:GXN75 RS05165
gene id: 714067:GXN75_RS05165
uniprot id: A0A1N7LBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS05825
gene id: 714067:GXN75_RS05825
uniprot id: A0A1N7MGE8
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS12455
gene id: 714067:GXN75_RS12455
uniprot id: A0A1N7KZK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

714067:GXN75 RS07130
gene id: 714067:GXN75_RS07130
uniprot id: A0A1N7M237
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

714067:GXN75 RS07905
gene id: 714067:GXN75_RS07905
uniprot id: A0A1N7IL57
names: Similarity
messages: Belongs to the ComB family.

714067:GXN75 RS09840
gene id: 714067:GXN75_RS09840
uniprot id: A0A1N7IWU4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

714067:GXN75 RS12810
gene id: 714067:GXN75_RS12810
uniprot id: A0A1N7KUW8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

714067:GXN75 RS14645
gene id: 714067:GXN75_RS14645
uniprot id: A0A1N7N9X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

714067:GXN75 RS16505
gene id: 714067:GXN75_RS16505
uniprot id: A0A1N7JTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

714067:GXN75 RS16375
gene id: 714067:GXN75_RS16375
uniprot id: A0A1N7JVT8
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10475
gene id: 714067:GXN75_RS10475
uniprot id: A0A1N7J0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

714067:GXN75 RS13955
gene id: 714067:GXN75_RS13955
uniprot id: A0A1N7KFU8
names: Subcellular Location Annotation
messages: Cytoplasm

714067:GXN75 RS01960
gene id: 714067:GXN75_RS01960
uniprot id: A0A1N7P3I7
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

714067:GXN75 RS06455
gene id: 714067:GXN75_RS06455
uniprot id: A0A1N7LV54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

714067:GXN75 RS07760
gene id: 714067:GXN75_RS07760
uniprot id: A0A1N7IKN7
names: Similarity
messages: Belongs to the AHA1 family.

714067:GXN75 RS06120
gene id: 714067:GXN75_RS06120
uniprot id: A0A1N7MJ06
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

714067:GXN75 RS11615
gene id: 714067:GXN75_RS11615
uniprot id: A0A1N7J7I6
names: Function
messages: Required for transformation and DNA binding.

714067:GXN75 RS06595
gene id: 714067:GXN75_RS06595
uniprot id: A0A1N7LWW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

714067:GXN75 RS12640
gene id: 714067:GXN75_RS12640
uniprot id: A0A1N7KXL6
names: Similarity
messages: Belongs to the UPF0145 family.

714067:GXN75 RS03765
gene id: 714067:GXN75_RS03765
uniprot id: A0A1N7NVQ1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

714067:GXN75 RS07330
gene id: 714067:GXN75_RS07330
uniprot id: A0A1N7M4H0
names: Cofactor
messages: Binds 1 FAD per subunit.

714067:GXN75 RS10935
gene id: 714067:GXN75_RS10935
uniprot id: A0A1N7J3L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

714067:GXN75 RS04820
gene id: 714067:GXN75_RS04820
uniprot id: A0A1N7LF44
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS12510
gene id: 714067:GXN75_RS12510
uniprot id: A0A1N7KYY7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

714067:GXN75 RS07900
gene id: 714067:GXN75_RS07900
uniprot id: A0A1N7IL64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS11600
gene id: 714067:GXN75_RS11600
uniprot id: A0A1N7J7A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

714067:GXN75 RS13430
gene id: 714067:GXN75_RS13430
uniprot id: A0A1N7KMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

714067:GXN75 RS04810
gene id: 714067:GXN75_RS04810
uniprot id: A0A1N7LFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS10750
gene id: 714067:GXN75_RS10750
uniprot id: A0A1N7J269
names: Similarity
messages: Belongs to the glutamate synthase family.

714067:GXN75 RS03890
gene id: 714067:GXN75_RS03890
uniprot id: A0A1N7NWZ3
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

714067:GXN75 RS01130
gene id: 714067:GXN75_RS01130
uniprot id: A0A1N7MYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

714067:GXN75 RS10470
gene id: 714067:GXN75_RS10470
uniprot id: A0A1N7J0P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

714067:GXN75 RS08875
gene id: 714067:GXN75_RS08875
uniprot id: A0A1N7IQZ6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS06535
gene id: 714067:GXN75_RS06535
uniprot id: A0A1N7LW24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS07105
gene id: 714067:GXN75_RS07105
uniprot id: A0A1N7M1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS09060
gene id: 714067:GXN75_RS09060
uniprot id: A0A1N7IS03
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10375
gene id: 714067:GXN75_RS10375
uniprot id: A0A1N7J033
names: Similarity
messages: Belongs to the KdgT transporter family.

714067:GXN75 RS15680
gene id: 714067:GXN75_RS15680
uniprot id: A0A1N7PFW2
names: Similarity
messages: Belongs to the peptidase C40 family.

714067:GXN75 RS15825
gene id: 714067:GXN75_RS15825
uniprot id: A0A1N7PDS1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

714067:GXN75 RS02450
gene id: 714067:GXN75_RS02450
uniprot id: A0A1N7NHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

714067:GXN75 RS03160
gene id: 714067:GXN75_RS03160
uniprot id: A0A1N7PZY0
names: Similarity
messages: Belongs to the arginase family.

714067:GXN75 RS10230
gene id: 714067:GXN75_RS10230
uniprot id: A0A1N7IYT7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

714067:GXN75 RS13005
gene id: 714067:GXN75_RS13005
uniprot id: A0A1N7KSI6
names: Similarity
messages: Belongs to the PspA/IM30 family.

714067:GXN75 RS11990
gene id: 714067:GXN75_RS11990
uniprot id: A0A1N7Q280
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS01340
gene id: 714067:GXN75_RS01340
uniprot id: A0A1N7N0I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

714067:GXN75 RS08000
gene id: 714067:GXN75_RS08000
uniprot id: A0A1N7ILW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS06795
gene id: 714067:GXN75_RS06795
uniprot id: A0A1N7LYT7
names: Similarity
messages: Belongs to the SleB family.

714067:GXN75 RS12620
gene id: 714067:GXN75_RS12620
uniprot id: A0A1N7KXJ2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

714067:GXN75 RS17065
gene id: 714067:GXN75_RS17065
uniprot id: A0A1N7JK82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

714067:GXN75 RS02690
gene id: 714067:GXN75_RS02690
uniprot id: A0A1N7NK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

714067:GXN75 RS01155
gene id: 714067:GXN75_RS01155
uniprot id: A0A1N7MYJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

714067:GXN75 RS02880
gene id: 714067:GXN75_RS02880
uniprot id: A0A1N7NM24
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

714067:GXN75 RS12895
gene id: 714067:GXN75_RS12895
uniprot id: A0A1N7KUB8
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS10760
gene id: 714067:GXN75_RS10760
uniprot id: A0A1N7J244
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

714067:GXN75 RS04890
gene id: 714067:GXN75_RS04890
uniprot id: A0A1N7LEF3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

714067:GXN75 RS08525
gene id: 714067:GXN75_RS08525
uniprot id: A0A1N7IPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

714067:GXN75 RS08290
gene id: 714067:GXN75_RS08290
uniprot id: A0A1N7IN58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

714067:GXN75 RS01810
gene id: 714067:GXN75_RS01810
uniprot id: A0A1N7P538
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS12365
gene id: 714067:GXN75_RS12365
uniprot id: A0A1N7PQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

714067:GXN75 RS15515
gene id: 714067:GXN75_RS15515
uniprot id: A0A1N7PK83
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

714067:GXN75 RS01050
gene id: 714067:GXN75_RS01050
uniprot id: A0A1N7MY41
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS06345
gene id: 714067:GXN75_RS06345
uniprot id: A0A1N7MLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS02425
gene id: 714067:GXN75_RS02425
uniprot id: A0A1N7NHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

714067:GXN75 RS05615
gene id: 714067:GXN75_RS05615
uniprot id: A0A1N7ME35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

714067:GXN75 RS02575
gene id: 714067:GXN75_RS02575
uniprot id: A0A1N7NIZ8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

714067:GXN75 RS08430
gene id: 714067:GXN75_RS08430
uniprot id: A0A1N7INX4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS16510
gene id: 714067:GXN75_RS16510
uniprot id: A0A1N7JTH3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS05140
gene id: 714067:GXN75_RS05140
uniprot id: A0A1N7LBH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

714067:GXN75 RS08005
gene id: 714067:GXN75_RS08005
uniprot id: A0A1N7ILK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

714067:GXN75 RS11135
gene id: 714067:GXN75_RS11135
uniprot id: A0A1N7J4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

714067:GXN75 RS10570
gene id: 714067:GXN75_RS10570
uniprot id: A0A1N7J141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

714067:GXN75 RS09650
gene id: 714067:GXN75_RS09650
uniprot id: A0A1N7IVU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

714067:GXN75 RS08795
gene id: 714067:GXN75_RS08795
uniprot id: A0A1N7IQJ7
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS08925
gene id: 714067:GXN75_RS08925
uniprot id: A0A1N7IR71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS11180
gene id: 714067:GXN75_RS11180
uniprot id: A0A1N7J4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

714067:GXN75 RS00915
gene id: 714067:GXN75_RS00915
uniprot id: A0A1N7MVT4
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS07070
gene id: 714067:GXN75_RS07070
uniprot id: A0A1N7M1I8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

714067:GXN75 RS16890
gene id: 714067:GXN75_RS16890
uniprot id: A0A1N7JMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

714067:GXN75 RS16970
gene id: 714067:GXN75_RS16970
uniprot id: A0A1N7JLB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

714067:GXN75 RS10170
gene id: 714067:GXN75_RS10170
uniprot id: A0A1N7IYR8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

714067:GXN75 RS07475
gene id: 714067:GXN75_RS07475
uniprot id: A0A1N7M664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

714067:GXN75 RS02600
gene id: 714067:GXN75_RS02600
uniprot id: A0A1N7NJ89
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

714067:GXN75 RS12185
gene id: 714067:GXN75_RS12185
uniprot id: A0A1N7PRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

714067:GXN75 RS03005
gene id: 714067:GXN75_RS03005
uniprot id: A0A1N7PYC0
names: Subcellular Location Annotation
messages: Cell membrane

714067:GXN75 RS01730
gene id: 714067:GXN75_RS01730
uniprot id: A0A1N7P609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

714067:GXN75 RS05670
gene id: 714067:GXN75_RS05670
uniprot id: A0A1N7MEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

714067:GXN75 RS09250
gene id: 714067:GXN75_RS09250
uniprot id: A0A1N7ISZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

714067:GXN75 RS05355
gene id: 714067:GXN75_RS05355
uniprot id: A0A1N7L9B8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

714067:GXN75 RS04460
gene id: 714067:GXN75_RS04460
uniprot id: A0A1N7LJE1
names: Similarity
messages: Belongs to the alkaline phosphatase family.

714067:GXN75 RS14495
gene id: 714067:GXN75_RS14495
uniprot id: A0A1N7NB10
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

714067:GXN75 RS12520
gene id: 714067:GXN75_RS12520
uniprot id: A0A1N7KYL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

714067:GXN75 RS11915
gene id: 714067:GXN75_RS11915
uniprot id: A0A1N7Q3D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS07120
gene id: 714067:GXN75_RS07120
uniprot id: A0A1N7M240
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

714067:GXN75 RS10795
gene id: 714067:GXN75_RS10795
uniprot id: A0A1N7J2C1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS05375
gene id: 714067:GXN75_RS05375
uniprot id: A0A1N7L8N2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

714067:GXN75 RS13460
gene id: 714067:GXN75_RS13460
uniprot id: A0A1N7KLV7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

714067:GXN75 RS01160
gene id: 714067:GXN75_RS01160
uniprot id: A0A1N7MYG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

714067:GXN75 RS12580
gene id: 714067:GXN75_RS12580
uniprot id: A0A1N7KXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

714067:GXN75 RS06310
gene id: 714067:GXN75_RS06310
uniprot id: A0A1N7MLM7
names: Subcellular Location Annotation
messages: Membrane

714067:GXN75 RS02375
gene id: 714067:GXN75_RS02375
uniprot id: A0A1N7PVL7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

714067:GXN75 RS02440
gene id: 714067:GXN75_RS02440
uniprot id: A0A1N7NHC8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

714067:GXN75 RS16485
gene id: 714067:GXN75_RS16485
uniprot id: A0A1N7JU19
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS16410
gene id: 714067:GXN75_RS16410
uniprot id: A0A1N7JVB0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

714067:GXN75 RS02145
gene id: 714067:GXN75_RS02145
uniprot id: A0A1N7P102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

714067:GXN75 RS16335
gene id: 714067:GXN75_RS16335
uniprot id: A0A1N7JWM7
names: Similarity
messages: Belongs to the HAM1 NTPase family.

714067:GXN75 RS08100
gene id: 714067:GXN75_RS08100
uniprot id: A0A1N7IM63
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

714067:GXN75 RS09645
gene id: 714067:GXN75_RS09645
uniprot id: A0A1N7IVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

714067:GXN75 RS10150
gene id: 714067:GXN75_RS10150
uniprot id: A0A1N7IYI3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

714067:GXN75 RS00765
gene id: 714067:GXN75_RS00765
uniprot id: A0A1N7MUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

714067:GXN75 RS16785
gene id: 714067:GXN75_RS16785
uniprot id: A0A1N7JP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

714067:GXN75 RS01940
gene id: 714067:GXN75_RS01940
uniprot id: A0A1N7P3Q5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

714067:GXN75 RS03605
gene id: 714067:GXN75_RS03605
uniprot id: A0A1N7NTM9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

714067:GXN75 RS12615
gene id: 714067:GXN75_RS12615
uniprot id: A0A1N7KXV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

714067:GXN75 RS10855
gene id: 714067:GXN75_RS10855
uniprot id: A0A1N7J2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS00650
gene id: 714067:GXN75_RS00650
uniprot id: A0A1N7MTM7
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

714067:GXN75 RS00260
gene id: 714067:GXN75_RS00260
uniprot id: A0A1N7JG43
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

714067:GXN75 RS07295
gene id: 714067:GXN75_RS07295
uniprot id: A0A1N7M4E9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

714067:GXN75 RS01095
gene id: 714067:GXN75_RS01095
uniprot id: A0A1N7MY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

714067:GXN75 RS08990
gene id: 714067:GXN75_RS08990
uniprot id: A0A1N7IRJ5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

714067:GXN75 RS02175
gene id: 714067:GXN75_RS02175
uniprot id: A0A1N7PXB6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

714067:GXN75 RS14205
gene id: 714067:GXN75_RS14205
uniprot id: A0A1N7NEK2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

714067:GXN75 RS10305
gene id: 714067:GXN75_RS10305
uniprot id: A0A1N7IZN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

714067:GXN75 RS01150
gene id: 714067:GXN75_RS01150
uniprot id: A0A1N7MZ72
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

714067:GXN75 RS04485
gene id: 714067:GXN75_RS04485
uniprot id: A0A1N7LJ91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

714067:GXN75 RS05310
gene id: 714067:GXN75_RS05310
uniprot id: A0A1N7L9F9
names: Similarity
messages: Belongs to the ribulokinase family.

714067:GXN75 RS10020
gene id: 714067:GXN75_RS10020
uniprot id: A0A1N7IY56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

714067:GXN75 RS09665
gene id: 714067:GXN75_RS09665
uniprot id: A0A1N7IVK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

714067:GXN75 RS07055
gene id: 714067:GXN75_RS07055
uniprot id: A0A1N7M1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

714067:GXN75 RS03140
gene id: 714067:GXN75_RS03140
uniprot id: A0A1N7PZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS03430
gene id: 714067:GXN75_RS03430
uniprot id: A0A1N7NRE3
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

714067:GXN75 RS08465
gene id: 714067:GXN75_RS08465
uniprot id: A0A1N7IP40
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

714067:GXN75 RS14305
gene id: 714067:GXN75_RS14305
uniprot id: A0A1N7NDH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

714067:GXN75 RS01470
gene id: 714067:GXN75_RS01470
uniprot id: A0A1N7N1P4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

714067:GXN75 RS15690
gene id: 714067:GXN75_RS15690
uniprot id: A0A1N7PFC8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

714067:GXN75 RS16865
gene id: 714067:GXN75_RS16865
uniprot id: A0A1N7JN43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

714067:GXN75 RS00480
gene id: 714067:GXN75_RS00480
uniprot id: A0A1N7JES6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

714067:GXN75 RS09655
gene id: 714067:GXN75_RS09655
uniprot id: A0A1N7IVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

714067:GXN75 RS07190
gene id: 714067:GXN75_RS07190
uniprot id: A0A1N7M2V2
names: Similarity
messages: Belongs to the SCO1/2 family.

714067:GXN75 RS12745
gene id: 714067:GXN75_RS12745
uniprot id: A0A1N7KVU1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

714067:GXN75 RS07495
gene id: 714067:GXN75_RS07495
uniprot id: A0A1N7M6A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS16180
gene id: 714067:GXN75_RS16180
uniprot id: A0A1N7JYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

714067:GXN75 RS05315
gene id: 714067:GXN75_RS05315
uniprot id: A0A1N7L9M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

714067:GXN75 RS10840
gene id: 714067:GXN75_RS10840
uniprot id: A0A1N7J2K1
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

714067:GXN75 RS11560
gene id: 714067:GXN75_RS11560
uniprot id: A0A1N7J761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS16700
gene id: 714067:GXN75_RS16700
uniprot id: A0A1N7JQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

714067:GXN75 RS15660
gene id: 714067:GXN75_RS15660
uniprot id: A0A1N7PGZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

714067:GXN75 RS12680
gene id: 714067:GXN75_RS12680
uniprot id: A0A1N7KWZ0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

714067:GXN75 RS03300
gene id: 714067:GXN75_RS03300
uniprot id: A0A1N7Q773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

714067:GXN75 RS14385
gene id: 714067:GXN75_RS14385
uniprot id: A0A1N7NC22
names: Similarity
messages: Belongs to the EamA transporter family.