709032:SULKU RS03300
gene id: 709032:SULKU_RS03300
uniprot id: E4U0U4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS05220
gene id: 709032:SULKU_RS05220
uniprot id: E4U327
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS04155
gene id: 709032:SULKU_RS04155
uniprot id: E4U1W4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

709032:SULKU RS05145
gene id: 709032:SULKU_RS05145
uniprot id: E4U312
names: Similarity
messages: Belongs to the threonine synthase family.

709032:SULKU RS02290
gene id: 709032:SULKU_RS02290
uniprot id: E4TZM8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

709032:SULKU RS12615
gene id: 709032:SULKU_RS12615
uniprot id: E4TYZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

709032:SULKU RS11560
gene id: 709032:SULKU_RS11560
uniprot id: E4TX89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

709032:SULKU RS03915
gene id: 709032:SULKU_RS03915
uniprot id: E4U1K3
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

709032:SULKU RS05980
gene id: 709032:SULKU_RS05980
uniprot id: E4TX09
names: Subcellular Location Annotation
messages: Secreted

709032:SULKU RS11215
gene id: 709032:SULKU_RS11215
uniprot id: E4TWP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

709032:SULKU RS03695
gene id: 709032:SULKU_RS03695
uniprot id: E4U190
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

709032:SULKU RS02480
gene id: 709032:SULKU_RS02480
uniprot id: E4TZZ0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

709032:SULKU RS11570
gene id: 709032:SULKU_RS11570
uniprot id: E4TX92
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

709032:SULKU RS12405
gene id: 709032:SULKU_RS12405
uniprot id: E4TYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS07990
gene id: 709032:SULKU_RS07990
uniprot id: E4U061
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS09175
gene id: 709032:SULKU_RS09175
uniprot id: E4U1F1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS11810
gene id: 709032:SULKU_RS11810
uniprot id: E4TXS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

709032:SULKU RS06445
gene id: 709032:SULKU_RS06445
uniprot id: E4TXN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

709032:SULKU RS05185
gene id: 709032:SULKU_RS05185
uniprot id: E4U320
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

709032:SULKU RS10430
gene id: 709032:SULKU_RS10430
uniprot id: E4U2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS00530
gene id: 709032:SULKU_RS00530
uniprot id: E4TWU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

709032:SULKU RS12785
gene id: 709032:SULKU_RS12785
uniprot id: E4TZG5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS04285
gene id: 709032:SULKU_RS04285
uniprot id: E4U1Z0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS04710
gene id: 709032:SULKU_RS04710
uniprot id: E4U2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

709032:SULKU RS03560
gene id: 709032:SULKU_RS03560
uniprot id: E4U163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

709032:SULKU RS06240
gene id: 709032:SULKU_RS06240
uniprot id: E4TXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

709032:SULKU RS07635
gene id: 709032:SULKU_RS07635
uniprot id: E4TZS1
names: Similarity
messages: Belongs to the ClpX chaperone family.

709032:SULKU RS02250
gene id: 709032:SULKU_RS02250
uniprot id: E4TZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

709032:SULKU RS00490
gene id: 709032:SULKU_RS00490
uniprot id: E4TWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

709032:SULKU RS00925
gene id: 709032:SULKU_RS00925
uniprot id: E4TXE9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

709032:SULKU RS10870
gene id: 709032:SULKU_RS10870
uniprot id: E4U3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

709032:SULKU RS05895
gene id: 709032:SULKU_RS05895
uniprot id: E4TWZ2
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS06300
gene id: 709032:SULKU_RS06300
uniprot id: E4TXK2
names: Similarity
messages: Belongs to the UPF0166 family.

709032:SULKU RS03880
gene id: 709032:SULKU_RS03880
uniprot id: E4U1J6
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS10660
gene id: 709032:SULKU_RS10660
uniprot id: E4U381
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00065
gene id: 709032:SULKU_RS00065
uniprot id: E4TW65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

709032:SULKU RS12810
gene id: 709032:SULKU_RS12810
uniprot id: E4TZH0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

709032:SULKU RS02915
gene id: 709032:SULKU_RS02915
uniprot id: E4U0E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

709032:SULKU RS13470
gene id: 709032:SULKU_RS13470
uniprot id: E4U3Q9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

709032:SULKU RS11195
gene id: 709032:SULKU_RS11195
uniprot id: E4TWN9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

709032:SULKU RS06930
gene id: 709032:SULKU_RS06930
uniprot id: E4TYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

709032:SULKU RS01670
gene id: 709032:SULKU_RS01670
uniprot id: E4TYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

709032:SULKU RS02630
gene id: 709032:SULKU_RS02630
uniprot id: E4U020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

709032:SULKU RS06415
gene id: 709032:SULKU_RS06415
uniprot id: E4TXM5
names: Similarity
messages: Belongs to the GPI family.

709032:SULKU RS07005
gene id: 709032:SULKU_RS07005
uniprot id: E4TYR1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

709032:SULKU RS03455
gene id: 709032:SULKU_RS03455
uniprot id: E4U142
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

709032:SULKU RS05690
gene id: 709032:SULKU_RS05690
uniprot id: E4TWH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

709032:SULKU RS01460
gene id: 709032:SULKU_RS01460
uniprot id: E4TYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

709032:SULKU RS03020
gene id: 709032:SULKU_RS03020
uniprot id: E4U0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

709032:SULKU RS05055
gene id: 709032:SULKU_RS05055
uniprot id: E4U2S8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS07815
gene id: 709032:SULKU_RS07815
uniprot id: E4TZV7
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

709032:SULKU RS07875
gene id: 709032:SULKU_RS07875
uniprot id: E4U038
names: Similarity
messages: Belongs to the LacAB/RpiB family.

709032:SULKU RS00240
gene id: 709032:SULKU_RS00240
uniprot id: E4TWA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

709032:SULKU RS04475
gene id: 709032:SULKU_RS04475
uniprot id: E4U298
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS01675
gene id: 709032:SULKU_RS01675
uniprot id: E4TYL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

709032:SULKU RS12585
gene id: 709032:SULKU_RS12585
uniprot id: E4TYZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

709032:SULKU RS09015
gene id: 709032:SULKU_RS09015
uniprot id: E4U1C0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

709032:SULKU RS07205
gene id: 709032:SULKU_RS07205
uniprot id: E4TZ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

709032:SULKU RS01995
gene id: 709032:SULKU_RS01995
uniprot id: E4TZ58
names: Similarity
messages: Belongs to the SAICAR synthetase family.

709032:SULKU RS09335
gene id: 709032:SULKU_RS09335
uniprot id: E4U1P8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

709032:SULKU RS08330
gene id: 709032:SULKU_RS08330
uniprot id: E4U0K1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09630
gene id: 709032:SULKU_RS09630
uniprot id: E4U223
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

709032:SULKU RS11295
gene id: 709032:SULKU_RS11295
uniprot id: E4TX40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00865
gene id: 709032:SULKU_RS00865
uniprot id: E4TXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

709032:SULKU RS00655
gene id: 709032:SULKU_RS00655
uniprot id: E4TWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS00765
gene id: 709032:SULKU_RS00765
uniprot id: E4TXB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

709032:SULKU RS07125
gene id: 709032:SULKU_RS07125
uniprot id: E4TYT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS12915
gene id: 709032:SULKU_RS12915
uniprot id: E4U3F0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

709032:SULKU RS12310
gene id: 709032:SULKU_RS12310
uniprot id: E4TYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

709032:SULKU RS06410
gene id: 709032:SULKU_RS06410
uniprot id: E4TXM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

709032:SULKU RS07555
gene id: 709032:SULKU_RS07555
uniprot id: E4TZQ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-115 inactivates the nitrogenase reductase and regulates nitrogenase activity.

709032:SULKU RS00370
gene id: 709032:SULKU_RS00370
uniprot id: E4TWR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

709032:SULKU RS02415
gene id: 709032:SULKU_RS02415
uniprot id: E4TZX7
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

709032:SULKU RS08040
gene id: 709032:SULKU_RS08040
uniprot id: E4U072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

709032:SULKU RS00285
gene id: 709032:SULKU_RS00285
uniprot id: E4TWB0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

709032:SULKU RS09215
gene id: 709032:SULKU_RS09215
uniprot id: E4U1G0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

709032:SULKU RS11405
gene id: 709032:SULKU_RS11405
uniprot id: E4TX62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

709032:SULKU RS02680
gene id: 709032:SULKU_RS02680
uniprot id: E4U030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS10045
gene id: 709032:SULKU_RS10045
uniprot id: E4U2G8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS09390
gene id: 709032:SULKU_RS09390
uniprot id: E4U1Q9
names: Similarity
messages: Belongs to the peptidase S11 family.

709032:SULKU RS01600
gene id: 709032:SULKU_RS01600
uniprot id: E4TYK3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

709032:SULKU RS05035
gene id: 709032:SULKU_RS05035
uniprot id: E4U2S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00820
gene id: 709032:SULKU_RS00820
uniprot id: E4TXC8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

709032:SULKU RS01465
gene id: 709032:SULKU_RS01465
uniprot id: E4TYH6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

709032:SULKU RS00740
gene id: 709032:SULKU_RS00740
uniprot id: E4TXB2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

709032:SULKU RS10565
gene id: 709032:SULKU_RS10565
uniprot id: E4U2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

709032:SULKU RS05160
gene id: 709032:SULKU_RS05160
uniprot id: E4U315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS09305
gene id: 709032:SULKU_RS09305
uniprot id: E4U1P2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS10450
gene id: 709032:SULKU_RS10450
uniprot id: E4U2X4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

709032:SULKU RS12510
gene id: 709032:SULKU_RS12510
uniprot id: E4TYY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

709032:SULKU RS02620
gene id: 709032:SULKU_RS02620
uniprot id: E4U018
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

709032:SULKU RS02285
gene id: 709032:SULKU_RS02285
uniprot id: E4TZM7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

709032:SULKU RS13990
gene id: 709032:SULKU_RS13990
uniprot id: E4U416
names: Similarity
messages: Belongs to the transposase 7 family.

709032:SULKU RS00720
gene id: 709032:SULKU_RS00720
uniprot id: E4TXA8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

709032:SULKU RS00205
gene id: 709032:SULKU_RS00205
uniprot id: E4TW94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

709032:SULKU RS09650
gene id: 709032:SULKU_RS09650
uniprot id: E4U227
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

709032:SULKU RS03280
gene id: 709032:SULKU_RS03280
uniprot id: E4U0U0
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS10185
gene id: 709032:SULKU_RS10185
uniprot id: E4U2J9
names: Similarity
messages: Belongs to the peptidase M1 family.

709032:SULKU RS10445
gene id: 709032:SULKU_RS10445
uniprot id: E4U2X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS03960
gene id: 709032:SULKU_RS03960
uniprot id: E4U1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

709032:SULKU RS01720
gene id: 709032:SULKU_RS01720
uniprot id: E4TZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

709032:SULKU RS04025
gene id: 709032:SULKU_RS04025
uniprot id: E4U1M0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

709032:SULKU RS14630
gene id: 709032:SULKU_RS14630
uniprot id: E4U3G8
names: Similarity
messages: Belongs to the ParB family.

709032:SULKU RS01680
gene id: 709032:SULKU_RS01680
uniprot id: E4TYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

709032:SULKU RS10230
gene id: 709032:SULKU_RS10230
uniprot id: E4U2K8
names: Similarity
messages: Belongs to the HupF/HypC family.

709032:SULKU RS02920
gene id: 709032:SULKU_RS02920
uniprot id: E4U0E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

709032:SULKU RS13660
gene id: 709032:SULKU_RS13660
uniprot id: E4U3U9
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS13765
gene id: 709032:SULKU_RS13765
uniprot id: E4U3X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS12460
gene id: 709032:SULKU_RS12460
uniprot id: E4TYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

709032:SULKU RS00930
gene id: 709032:SULKU_RS00930
uniprot id: E4TXF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS12065
gene id: 709032:SULKU_RS12065
uniprot id: E4TYB3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

709032:SULKU RS11315
gene id: 709032:SULKU_RS11315
uniprot id: E4TX44
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

709032:SULKU RS06395
gene id: 709032:SULKU_RS06395
uniprot id: E4TXM1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

709032:SULKU RS13775
gene id: 709032:SULKU_RS13775
uniprot id: E4U3X2
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS10750
gene id: 709032:SULKU_RS10750
uniprot id: E4U398
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

709032:SULKU RS04720
gene id: 709032:SULKU_RS04720
uniprot id: E4U2E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

709032:SULKU RS00010
gene id: 709032:SULKU_RS00010
uniprot id: E4TW54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

709032:SULKU RS07600
gene id: 709032:SULKU_RS07600
uniprot id: E4TZR4
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

709032:SULKU RS05875
gene id: 709032:SULKU_RS05875
uniprot id: E4TWY8
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01550
gene id: 709032:SULKU_RS01550
uniprot id: E4TYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

709032:SULKU RS09275
gene id: 709032:SULKU_RS09275
uniprot id: E4U1N6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

709032:SULKU RS03835
gene id: 709032:SULKU_RS03835
uniprot id: E4U1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

709032:SULKU RS03040
gene id: 709032:SULKU_RS03040
uniprot id: E4U0H1
names: Similarity
messages: Belongs to the aspartokinase family.

709032:SULKU RS13210
gene id: 709032:SULKU_RS13210
uniprot id: E4U3K9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

709032:SULKU RS04340
gene id: 709032:SULKU_RS04340
uniprot id: E4U203
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

709032:SULKU RS02435
gene id: 709032:SULKU_RS02435
uniprot id: E4TZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

709032:SULKU RS01790
gene id: 709032:SULKU_RS01790
uniprot id: E4TZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

709032:SULKU RS06475
gene id: 709032:SULKU_RS06475
uniprot id: E4TY26
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

709032:SULKU RS03420
gene id: 709032:SULKU_RS03420
uniprot id: E4U135
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

709032:SULKU RS11910
gene id: 709032:SULKU_RS11910
uniprot id: E4TXU1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

709032:SULKU RS11520
gene id: 709032:SULKU_RS11520
uniprot id: E4TX81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

709032:SULKU RS07885
gene id: 709032:SULKU_RS07885
uniprot id: E4U040
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS05585
gene id: 709032:SULKU_RS05585
uniprot id: E4TWF3
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09555
gene id: 709032:SULKU_RS09555
uniprot id: E4U1U3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS04105
gene id: 709032:SULKU_RS04105
uniprot id: E4U1V4
names: Subcellular Location Annotation
messages: Cytoplasm

709032:SULKU RS11395
gene id: 709032:SULKU_RS11395
uniprot id: E4TX60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

709032:SULKU RS00960
gene id: 709032:SULKU_RS00960
uniprot id: E4TXF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

709032:SULKU RS10830
gene id: 709032:SULKU_RS10830
uniprot id: E4U3B4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

709032:SULKU RS07705
gene id: 709032:SULKU_RS07705
uniprot id: E4TZT5
names: Similarity
messages: Belongs to the NifX/NifY family.

709032:SULKU RS13100
gene id: 709032:SULKU_RS13100
uniprot id: E4U3I6
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS10225
gene id: 709032:SULKU_RS10225
uniprot id: E4U2K7
names: Similarity
messages: Belongs to the HypD family.

709032:SULKU RS01355
gene id: 709032:SULKU_RS01355
uniprot id: E4TY19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS09200
gene id: 709032:SULKU_RS09200
uniprot id: E4U1F7
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS01255
gene id: 709032:SULKU_RS01255
uniprot id: E4TXZ9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

709032:SULKU RS01425
gene id: 709032:SULKU_RS01425
uniprot id: E4TYG9
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS11555
gene id: 709032:SULKU_RS11555
uniprot id: E4TX88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

709032:SULKU RS12820
gene id: 709032:SULKU_RS12820
uniprot id: E4TZH2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

709032:SULKU RS09330
gene id: 709032:SULKU_RS09330
uniprot id: E4U1P7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

709032:SULKU RS01025
gene id: 709032:SULKU_RS01025
uniprot id: E4TXV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

709032:SULKU RS08100
gene id: 709032:SULKU_RS08100
uniprot id: E4U085
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

709032:SULKU RS11850
gene id: 709032:SULKU_RS11850
uniprot id: E4TXS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

709032:SULKU RS09645
gene id: 709032:SULKU_RS09645
uniprot id: E4U226
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09480
gene id: 709032:SULKU_RS09480
uniprot id: E4U1S7
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS05775
gene id: 709032:SULKU_RS05775
uniprot id: E4TWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS05750
gene id: 709032:SULKU_RS05750
uniprot id: E4TWI6
names: Similarity
messages: Belongs to the NadC/ModD family.

709032:SULKU RS04165
gene id: 709032:SULKU_RS04165
uniprot id: E4U1W6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

709032:SULKU RS14395
gene id: 709032:SULKU_RS14395
uniprot id: E4TYN3
names: Similarity
messages: Belongs to the peptidase C40 family.

709032:SULKU RS14340
gene id: 709032:SULKU_RS14340
uniprot id: E4U343
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01545
gene id: 709032:SULKU_RS01545
uniprot id: E4TYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

709032:SULKU RS04945
gene id: 709032:SULKU_RS04945
uniprot id: E4U2Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

709032:SULKU RS06890
gene id: 709032:SULKU_RS06890
uniprot id: E4TYN8
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

709032:SULKU RS04010
gene id: 709032:SULKU_RS04010
uniprot id: E4U1L6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

709032:SULKU RS11165
gene id: 709032:SULKU_RS11165
uniprot id: E4TWN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

709032:SULKU RS02335
gene id: 709032:SULKU_RS02335
uniprot id: E4TZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

709032:SULKU RS11645
gene id: 709032:SULKU_RS11645
uniprot id: E4TXN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

709032:SULKU RS02520
gene id: 709032:SULKU_RS02520
uniprot id: E4TZZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

709032:SULKU RS11400
gene id: 709032:SULKU_RS11400
uniprot id: E4TX61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

709032:SULKU RS06170
gene id: 709032:SULKU_RS06170
uniprot id: E4TXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS03130
gene id: 709032:SULKU_RS03130
uniprot id: E4U0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

709032:SULKU RS04170
gene id: 709032:SULKU_RS04170
uniprot id: E4U1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

709032:SULKU RS09605
gene id: 709032:SULKU_RS09605
uniprot id: E4U218
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

709032:SULKU RS02625
gene id: 709032:SULKU_RS02625
uniprot id: E4U019
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

709032:SULKU RS04575
gene id: 709032:SULKU_RS04575
uniprot id: E4U2B7
names: Caution
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06040
gene id: 709032:SULKU_RS06040
uniprot id: E4TX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

709032:SULKU RS10470
gene id: 709032:SULKU_RS10470
uniprot id: E4U2X8
names: Similarity
messages: Belongs to the P(II) protein family.

709032:SULKU RS05015
gene id: 709032:SULKU_RS05015
uniprot id: E4U2R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

709032:SULKU RS03755
gene id: 709032:SULKU_RS03755
uniprot id: E4U1H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

709032:SULKU RS10325
gene id: 709032:SULKU_RS10325
uniprot id: E4U2V0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

709032:SULKU RS05865
gene id: 709032:SULKU_RS05865
uniprot id: E4TWY6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS11455
gene id: 709032:SULKU_RS11455
uniprot id: E4TX72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

709032:SULKU RS04015
gene id: 709032:SULKU_RS04015
uniprot id: E4U1L8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

709032:SULKU RS01695
gene id: 709032:SULKU_RS01695
uniprot id: E4TZ01
names: Similarity
messages: Belongs to the GARS family.

709032:SULKU RS12030
gene id: 709032:SULKU_RS12030
uniprot id: E4TYA6
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS00095
gene id: 709032:SULKU_RS00095
uniprot id: E4TW71
names: Subcellular Location Annotation
messages: Cell outer membrane

709032:SULKU RS04435
gene id: 709032:SULKU_RS04435
uniprot id: E4U290
names: Similarity
messages: Belongs to the UbiD family.

709032:SULKU RS10820
gene id: 709032:SULKU_RS10820
uniprot id: E4U3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

709032:SULKU RS03405
gene id: 709032:SULKU_RS03405
uniprot id: E4U132
names: Similarity
messages: Belongs to the peptidase S1C family.

709032:SULKU RS11915
gene id: 709032:SULKU_RS11915
uniprot id: E4TXU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS09600
gene id: 709032:SULKU_RS09600
uniprot id: E4U217
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

709032:SULKU RS02505
gene id: 709032:SULKU_RS02505
uniprot id: E4TZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

709032:SULKU RS00320
gene id: 709032:SULKU_RS00320
uniprot id: E4TWB7
names: Subcellular Location Annotation
messages: Mitochondrion matrix

709032:SULKU RS10235
gene id: 709032:SULKU_RS10235
uniprot id: E4U2K9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

709032:SULKU RS05575
gene id: 709032:SULKU_RS05575
uniprot id: E4TWF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

709032:SULKU RS09190
gene id: 709032:SULKU_RS09190
uniprot id: E4U1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

709032:SULKU RS03710
gene id: 709032:SULKU_RS03710
uniprot id: E4U193
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

709032:SULKU RS07105
gene id: 709032:SULKU_RS07105
uniprot id: E4TYT2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06420
gene id: 709032:SULKU_RS06420
uniprot id: E4TXM6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

709032:SULKU RS06450
gene id: 709032:SULKU_RS06450
uniprot id: E4TXN2
names: Similarity
messages: Belongs to the DEAD box helicase family.

709032:SULKU RS02760
gene id: 709032:SULKU_RS02760
uniprot id: E4U0B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

709032:SULKU RS07375
gene id: 709032:SULKU_RS07375
uniprot id: E4TZB2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

709032:SULKU RS06220
gene id: 709032:SULKU_RS06220
uniprot id: E4TXI6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

709032:SULKU RS14235
gene id: 709032:SULKU_RS14235
uniprot id: E4U144
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09235
gene id: 709032:SULKU_RS09235
uniprot id: E4U1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

709032:SULKU RS11365
gene id: 709032:SULKU_RS11365
uniprot id: E4TX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

709032:SULKU RS10645
gene id: 709032:SULKU_RS10645
uniprot id: E4U378
names: Similarity
messages: Belongs to the ABC transporter superfamily.

709032:SULKU RS09660
gene id: 709032:SULKU_RS09660
uniprot id: E4U229
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS08045
gene id: 709032:SULKU_RS08045
uniprot id: E4U073
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

709032:SULKU RS10715
gene id: 709032:SULKU_RS10715
uniprot id: E4U391
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS10000
gene id: 709032:SULKU_RS10000
uniprot id: E4U2F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

709032:SULKU RS02035
gene id: 709032:SULKU_RS02035
uniprot id: E4TZ66
names: Similarity
messages: Belongs to the SUI1 family.

709032:SULKU RS12650
gene id: 709032:SULKU_RS12650
uniprot id: E4TZD8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

709032:SULKU RS08140
gene id: 709032:SULKU_RS08140
uniprot id: E4U093
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS03085
gene id: 709032:SULKU_RS03085
uniprot id: E4U0Q1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

709032:SULKU RS04225
gene id: 709032:SULKU_RS04225
uniprot id: E4U1X8
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

709032:SULKU RS01330
gene id: 709032:SULKU_RS01330
uniprot id: E4TY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

709032:SULKU RS09040
gene id: 709032:SULKU_RS09040
uniprot id: E4U1C5
names: Similarity
messages: Belongs to the MipA/OmpV family.

709032:SULKU RS07050
gene id: 709032:SULKU_RS07050
uniprot id: E4TYS0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

709032:SULKU RS09440
gene id: 709032:SULKU_RS09440
uniprot id: E4U1R9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

709032:SULKU RS07230
gene id: 709032:SULKU_RS07230
uniprot id: E4TZ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS12420
gene id: 709032:SULKU_RS12420
uniprot id: E4TYW4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

709032:SULKU RS11940
gene id: 709032:SULKU_RS11940
uniprot id: E4TXU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06480
gene id: 709032:SULKU_RS06480
uniprot id: E4TY27
names: Similarity
messages: Belongs to the UPF0763 family.

709032:SULKU RS12715
gene id: 709032:SULKU_RS12715
uniprot id: E4TZF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

709032:SULKU RS13870
gene id: 709032:SULKU_RS13870
uniprot id: E4U3Z0
names: Similarity
messages: Belongs to the ParB family.

709032:SULKU RS04940
gene id: 709032:SULKU_RS04940
uniprot id: E4U2Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

709032:SULKU RS01145
gene id: 709032:SULKU_RS01145
uniprot id: E4TXX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

709032:SULKU RS10990
gene id: 709032:SULKU_RS10990
uniprot id: E4TWJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

709032:SULKU RS11335
gene id: 709032:SULKU_RS11335
uniprot id: E4TX48
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

709032:SULKU RS08370
gene id: 709032:SULKU_RS08370
uniprot id: E4U0K9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

709032:SULKU RS00550
gene id: 709032:SULKU_RS00550
uniprot id: E4TWU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

709032:SULKU RS08760
gene id: 709032:SULKU_RS08760
uniprot id: E4U104
names: Similarity
messages: Belongs to the TrpC family.

709032:SULKU RS00975
gene id: 709032:SULKU_RS00975
uniprot id: E4TXF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

709032:SULKU RS03185
gene id: 709032:SULKU_RS03185
uniprot id: E4U0S1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS11530
gene id: 709032:SULKU_RS11530
uniprot id: E4TX83
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01190
gene id: 709032:SULKU_RS01190
uniprot id: E4TXY6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

709032:SULKU RS03015
gene id: 709032:SULKU_RS03015
uniprot id: E4U0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

709032:SULKU RS08945
gene id: 709032:SULKU_RS08945
uniprot id: E4U1A6
names: Similarity
messages: Belongs to the SCO1/2 family.

709032:SULKU RS03140
gene id: 709032:SULKU_RS03140
uniprot id: E4U0R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

709032:SULKU RS06035
gene id: 709032:SULKU_RS06035
uniprot id: E4TX19
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01570
gene id: 709032:SULKU_RS01570
uniprot id: E4TYJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

709032:SULKU RS08975
gene id: 709032:SULKU_RS08975
uniprot id: E4U1B2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

709032:SULKU RS10825
gene id: 709032:SULKU_RS10825
uniprot id: E4U3B3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

709032:SULKU RS11600
gene id: 709032:SULKU_RS11600
uniprot id: E4TX98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

709032:SULKU RS01850
gene id: 709032:SULKU_RS01850
uniprot id: E4TZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

709032:SULKU RS00005
gene id: 709032:SULKU_RS00005
uniprot id: E4TW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

709032:SULKU RS10685
gene id: 709032:SULKU_RS10685
uniprot id: E4U385
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

709032:SULKU RS03025
gene id: 709032:SULKU_RS03025
uniprot id: E4U0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

709032:SULKU RS13190
gene id: 709032:SULKU_RS13190
uniprot id: E4U3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

709032:SULKU RS11140
gene id: 709032:SULKU_RS11140
uniprot id: E4TWM9
names: Similarity
messages: Belongs to the pirin family.

709032:SULKU RS04345
gene id: 709032:SULKU_RS04345
uniprot id: E4U204
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

709032:SULKU RS13370
gene id: 709032:SULKU_RS13370
uniprot id: E4U3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

709032:SULKU RS00365
gene id: 709032:SULKU_RS00365
uniprot id: E4TWR2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

709032:SULKU RS08735
gene id: 709032:SULKU_RS08735
uniprot id: E4U0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

709032:SULKU RS10005
gene id: 709032:SULKU_RS10005
uniprot id: E4U2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

709032:SULKU RS01920
gene id: 709032:SULKU_RS01920
uniprot id: E4TZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

709032:SULKU RS03090
gene id: 709032:SULKU_RS03090
uniprot id: E4U0Q2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

709032:SULKU RS11340
gene id: 709032:SULKU_RS11340
uniprot id: E4TX49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

709032:SULKU RS02770
gene id: 709032:SULKU_RS02770
uniprot id: E4U0B5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS04555
gene id: 709032:SULKU_RS04555
uniprot id: E4U2B4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

709032:SULKU RS01245
gene id: 709032:SULKU_RS01245
uniprot id: E4TXZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS02470
gene id: 709032:SULKU_RS02470
uniprot id: E4TZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

709032:SULKU RS02360
gene id: 709032:SULKU_RS02360
uniprot id: E4TZW6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

709032:SULKU RS08015
gene id: 709032:SULKU_RS08015
uniprot id: E4U067
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

709032:SULKU RS05840
gene id: 709032:SULKU_RS05840
uniprot id: E4TWY1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06385
gene id: 709032:SULKU_RS06385
uniprot id: E4TXL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

709032:SULKU RS14325
gene id: 709032:SULKU_RS14325
uniprot id: E4U2P8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS10140
gene id: 709032:SULKU_RS10140
uniprot id: E4U2I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

709032:SULKU RS10690
gene id: 709032:SULKU_RS10690
uniprot id: E4U386
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

709032:SULKU RS11310
gene id: 709032:SULKU_RS11310
uniprot id: E4TX43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

709032:SULKU RS10305
gene id: 709032:SULKU_RS10305
uniprot id: E4U2U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

709032:SULKU RS12135
gene id: 709032:SULKU_RS12135
uniprot id: E4TYC7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

709032:SULKU RS10400
gene id: 709032:SULKU_RS10400
uniprot id: E4U2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

709032:SULKU RS00105
gene id: 709032:SULKU_RS00105
uniprot id: E4TW73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

709032:SULKU RS09985
gene id: 709032:SULKU_RS09985
uniprot id: E4U2F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

709032:SULKU RS14645
gene id: 709032:SULKU_RS14645
uniprot id: E4U3I9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS01240
gene id: 709032:SULKU_RS01240
uniprot id: E4TXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

709032:SULKU RS07900
gene id: 709032:SULKU_RS07900
uniprot id: E4U043
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

709032:SULKU RS07220
gene id: 709032:SULKU_RS07220
uniprot id: E4TZ81
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

709032:SULKU RS04125
gene id: 709032:SULKU_RS04125
uniprot id: E4U1V8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

709032:SULKU RS13160
gene id: 709032:SULKU_RS13160
uniprot id: E4U3J9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

709032:SULKU RS07605
gene id: 709032:SULKU_RS07605
uniprot id: E4TZR5
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

709032:SULKU RS00700
gene id: 709032:SULKU_RS00700
uniprot id: E4TXA4
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS12965
gene id: 709032:SULKU_RS12965
uniprot id: E4U3G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

709032:SULKU RS01480
gene id: 709032:SULKU_RS01480
uniprot id: E4TYH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS07540
gene id: 709032:SULKU_RS07540
uniprot id: E4TZQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

709032:SULKU RS03195
gene id: 709032:SULKU_RS03195
uniprot id: E4U0S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

709032:SULKU RS01180
gene id: 709032:SULKU_RS01180
uniprot id: E4TXY4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

709032:SULKU RS03305
gene id: 709032:SULKU_RS03305
uniprot id: E4U0U5
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01875
gene id: 709032:SULKU_RS01875
uniprot id: E4TZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

709032:SULKU RS07185
gene id: 709032:SULKU_RS07185
uniprot id: E4TZ74
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

709032:SULKU RS11935
gene id: 709032:SULKU_RS11935
uniprot id: E4TXU6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

709032:SULKU RS06560
gene id: 709032:SULKU_RS06560
uniprot id: E4TY43
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

709032:SULKU RS12160
gene id: 709032:SULKU_RS12160
uniprot id: E4TYD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS12735
gene id: 709032:SULKU_RS12735
uniprot id: E4TZF5
names: Subcellular Location Annotation
messages: Cytoplasm

709032:SULKU RS02075
gene id: 709032:SULKU_RS02075
uniprot id: E4TZI5
names: Similarity
messages: Belongs to the FrmR/RcnR family.

709032:SULKU RS11895
gene id: 709032:SULKU_RS11895
uniprot id: E4TXT8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

709032:SULKU RS11700
gene id: 709032:SULKU_RS11700
uniprot id: E4TXP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

709032:SULKU RS07200
gene id: 709032:SULKU_RS07200
uniprot id: E4TZ77
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

709032:SULKU RS03845
gene id: 709032:SULKU_RS03845
uniprot id: E4U1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

709032:SULKU RS01685
gene id: 709032:SULKU_RS01685
uniprot id: E4TYM1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

709032:SULKU RS13935
gene id: 709032:SULKU_RS13935
uniprot id: E4U405
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

709032:SULKU RS05115
gene id: 709032:SULKU_RS05115
uniprot id: E4U306
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

709032:SULKU RS05260
gene id: 709032:SULKU_RS05260
uniprot id: E4U335
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

709032:SULKU RS09655
gene id: 709032:SULKU_RS09655
uniprot id: E4U228
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

709032:SULKU RS00850
gene id: 709032:SULKU_RS00850
uniprot id: E4TXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

709032:SULKU RS09100
gene id: 709032:SULKU_RS09100
uniprot id: E4U1D7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS11660
gene id: 709032:SULKU_RS11660
uniprot id: E4TXP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

709032:SULKU RS01575
gene id: 709032:SULKU_RS01575
uniprot id: E4TYJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

709032:SULKU RS03410
gene id: 709032:SULKU_RS03410
uniprot id: E4U133
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

709032:SULKU RS07445
gene id: 709032:SULKU_RS07445
uniprot id: E4TZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

709032:SULKU RS00715
gene id: 709032:SULKU_RS00715
uniprot id: E4TXA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS11765
gene id: 709032:SULKU_RS11765
uniprot id: E4TXR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

709032:SULKU RS11825
gene id: 709032:SULKU_RS11825
uniprot id: E4TXS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

709032:SULKU RS11510
gene id: 709032:SULKU_RS11510
uniprot id: E4TX79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

709032:SULKU RS07360
gene id: 709032:SULKU_RS07360
uniprot id: E4TZA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

709032:SULKU RS03840
gene id: 709032:SULKU_RS03840
uniprot id: E4U1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

709032:SULKU RS09485
gene id: 709032:SULKU_RS09485
uniprot id: E4U1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

709032:SULKU RS08070
gene id: 709032:SULKU_RS08070
uniprot id: E4U079
names: Subcellular Location Annotation
messages: Mitochondrion

709032:SULKU RS01350
gene id: 709032:SULKU_RS01350
uniprot id: E4TY18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS02535
gene id: 709032:SULKU_RS02535
uniprot id: E4U001
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

709032:SULKU RS02805
gene id: 709032:SULKU_RS02805
uniprot id: E4U0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

709032:SULKU RS04260
gene id: 709032:SULKU_RS04260
uniprot id: E4U1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

709032:SULKU RS03310
gene id: 709032:SULKU_RS03310
uniprot id: E4U0U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

709032:SULKU RS01120
gene id: 709032:SULKU_RS01120
uniprot id: E4TXX2
names: Similarity
messages: Belongs to the UPF0102 family.

709032:SULKU RS05615
gene id: 709032:SULKU_RS05615
uniprot id: E4TWF9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

709032:SULKU RS11330
gene id: 709032:SULKU_RS11330
uniprot id: E4TX47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

709032:SULKU RS13110
gene id: 709032:SULKU_RS13110
uniprot id: E4U3I8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS04295
gene id: 709032:SULKU_RS04295
uniprot id: E4U1Z3
names: Similarity
messages: Belongs to the UPF0751 family.

709032:SULKU RS09295
gene id: 709032:SULKU_RS09295
uniprot id: E4U1P0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

709032:SULKU RS11630
gene id: 709032:SULKU_RS11630
uniprot id: E4TXN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

709032:SULKU RS01105
gene id: 709032:SULKU_RS01105
uniprot id: E4TXW9
names: Similarity
messages: Belongs to the CvfB family.

709032:SULKU RS00770
gene id: 709032:SULKU_RS00770
uniprot id: E4TXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

709032:SULKU RS03335
gene id: 709032:SULKU_RS03335
uniprot id: E4U0V1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

709032:SULKU RS14545
gene id: 709032:SULKU_RS14545
uniprot id: E4U2I3
names: Similarity
messages: Belongs to the UPF0251 family.

709032:SULKU RS04605
gene id: 709032:SULKU_RS04605
uniprot id: E4U2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

709032:SULKU RS13080
gene id: 709032:SULKU_RS13080
uniprot id: E4U3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

709032:SULKU RS02575
gene id: 709032:SULKU_RS02575
uniprot id: E4U009
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

709032:SULKU RS07670
gene id: 709032:SULKU_RS07670
uniprot id: E4TZS8
names: Similarity
messages: Belongs to the pirin family.

709032:SULKU RS02205
gene id: 709032:SULKU_RS02205
uniprot id: E4TZL1
names: Subcellular Location Annotation
messages: Cell outer membrane

709032:SULKU RS01420
gene id: 709032:SULKU_RS01420
uniprot id: E4TYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS05900
gene id: 709032:SULKU_RS05900
uniprot id: E4TWZ3
names: Similarity
messages: Belongs to the ArsC family.

709032:SULKU RS13390
gene id: 709032:SULKU_RS13390
uniprot id: E4U3P1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

709032:SULKU RS05950
gene id: 709032:SULKU_RS05950
uniprot id: E4TX03
names: Similarity
messages: Belongs to the GPI family.

709032:SULKU RS06165
gene id: 709032:SULKU_RS06165
uniprot id: E4TXH8
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS05835
gene id: 709032:SULKU_RS05835
uniprot id: E4TWY0
names: Similarity
messages: Belongs to the ModE family.

709032:SULKU RS02410
gene id: 709032:SULKU_RS02410
uniprot id: E4TZX6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

709032:SULKU RS00480
gene id: 709032:SULKU_RS00480
uniprot id: E4TWT3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

709032:SULKU RS03620
gene id: 709032:SULKU_RS03620
uniprot id: E4U175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

709032:SULKU RS00120
gene id: 709032:SULKU_RS00120
uniprot id: E4TW76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS07315
gene id: 709032:SULKU_RS07315
uniprot id: E4TZA0
names: Similarity
messages: Belongs to the SCO1/2 family.

709032:SULKU RS02755
gene id: 709032:SULKU_RS02755
uniprot id: E4U0B2
names: Subcellular Location Annotation
messages: Cytoplasm

709032:SULKU RS06245
gene id: 709032:SULKU_RS06245
uniprot id: E4TXJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00265
gene id: 709032:SULKU_RS00265
uniprot id: E4TWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS06305
gene id: 709032:SULKU_RS06305
uniprot id: E4TXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

709032:SULKU RS12760
gene id: 709032:SULKU_RS12760
uniprot id: E4TZG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

709032:SULKU RS01515
gene id: 709032:SULKU_RS01515
uniprot id: E4TYI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS05375
gene id: 709032:SULKU_RS05375
uniprot id: E4U358
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01610
gene id: 709032:SULKU_RS01610
uniprot id: E4TYK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

709032:SULKU RS11025
gene id: 709032:SULKU_RS11025
uniprot id: E4TWK6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

709032:SULKU RS01170
gene id: 709032:SULKU_RS01170
uniprot id: E4TXY2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

709032:SULKU RS10540
gene id: 709032:SULKU_RS10540
uniprot id: E4U2Z0
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS11070
gene id: 709032:SULKU_RS11070
uniprot id: E4TWL5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

709032:SULKU RS01040
gene id: 709032:SULKU_RS01040
uniprot id: E4TXV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

709032:SULKU RS10475
gene id: 709032:SULKU_RS10475
uniprot id: E4U2X9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06320
gene id: 709032:SULKU_RS06320
uniprot id: E4TXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS11625
gene id: 709032:SULKU_RS11625
uniprot id: E4TXN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01070
gene id: 709032:SULKU_RS01070
uniprot id: E4TXW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

709032:SULKU RS00525
gene id: 709032:SULKU_RS00525
uniprot id: E4TWU2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

709032:SULKU RS06630
gene id: 709032:SULKU_RS06630
uniprot id: E4TY57
names: Similarity
messages: Belongs to the AlaDH/PNT family.

709032:SULKU RS07960
gene id: 709032:SULKU_RS07960
uniprot id: E4U055
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS11410
gene id: 709032:SULKU_RS11410
uniprot id: E4TX63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

709032:SULKU RS05010
gene id: 709032:SULKU_RS05010
uniprot id: E4U2R8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

709032:SULKU RS05340
gene id: 709032:SULKU_RS05340
uniprot id: E4U351
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

709032:SULKU RS11870
gene id: 709032:SULKU_RS11870
uniprot id: E4TXT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

709032:SULKU RS04190
gene id: 709032:SULKU_RS04190
uniprot id: E4U1X1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS14230
gene id: 709032:SULKU_RS14230
uniprot id: E4U141
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

709032:SULKU RS02600
gene id: 709032:SULKU_RS02600
uniprot id: E4U014
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

709032:SULKU RS01065
gene id: 709032:SULKU_RS01065
uniprot id: E4TXW1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

709032:SULKU RS10335
gene id: 709032:SULKU_RS10335
uniprot id: E4U2V2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

709032:SULKU RS04505
gene id: 709032:SULKU_RS04505
uniprot id: E4U2A4
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS04995
gene id: 709032:SULKU_RS04995
uniprot id: E4U2R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01505
gene id: 709032:SULKU_RS01505
uniprot id: E4TYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

709032:SULKU RS04550
gene id: 709032:SULKU_RS04550
uniprot id: E4U2B3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

709032:SULKU RS01780
gene id: 709032:SULKU_RS01780
uniprot id: E4TZ16
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

709032:SULKU RS09465
gene id: 709032:SULKU_RS09465
uniprot id: E4U1S4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

709032:SULKU RS05485
gene id: 709032:SULKU_RS05485
uniprot id: E4TWD3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

709032:SULKU RS14555
gene id: 709032:SULKU_RS14555
uniprot id: E4U2J5
names: Subcellular Location Annotation
messages: Cell inner membrane

709032:SULKU RS06340
gene id: 709032:SULKU_RS06340
uniprot id: E4TXL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS10850
gene id: 709032:SULKU_RS10850
uniprot id: E4U3B8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

709032:SULKU RS08970
gene id: 709032:SULKU_RS08970
uniprot id: E4U1B1
names: Similarity
messages: Belongs to the nitroreductase family.

709032:SULKU RS01990
gene id: 709032:SULKU_RS01990
uniprot id: E4TZ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

709032:SULKU RS14670
gene id: 709032:SULKU_RS14670
uniprot id: E4U3V1
names: Similarity
messages: Belongs to the transposase 7 family.

709032:SULKU RS00735
gene id: 709032:SULKU_RS00735
uniprot id: E4TXB1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

709032:SULKU RS03535
gene id: 709032:SULKU_RS03535
uniprot id: E4U158
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

709032:SULKU RS05605
gene id: 709032:SULKU_RS05605
uniprot id: E4TWF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS04480
gene id: 709032:SULKU_RS04480
uniprot id: E4U299
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

709032:SULKU RS06550
gene id: 709032:SULKU_RS06550
uniprot id: E4TY41
names: Similarity
messages: Belongs to the NifX/NifY family.

709032:SULKU RS05715
gene id: 709032:SULKU_RS05715
uniprot id: E4TWH9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

709032:SULKU RS03895
gene id: 709032:SULKU_RS03895
uniprot id: E4U1J9
names: Similarity
messages: Belongs to the fabD family.

709032:SULKU RS12780
gene id: 709032:SULKU_RS12780
uniprot id: E4TZG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

709032:SULKU RS09625
gene id: 709032:SULKU_RS09625
uniprot id: E4U222
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

709032:SULKU RS09810
gene id: 709032:SULKU_RS09810
uniprot id: E4U252
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

709032:SULKU RS03825
gene id: 709032:SULKU_RS03825
uniprot id: E4U1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

709032:SULKU RS09510
gene id: 709032:SULKU_RS09510
uniprot id: E4U1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

709032:SULKU RS07860
gene id: 709032:SULKU_RS07860
uniprot id: E4TZW4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS10550
gene id: 709032:SULKU_RS10550
uniprot id: E4U2Z2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

709032:SULKU RS12270
gene id: 709032:SULKU_RS12270
uniprot id: E4TYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS11440
gene id: 709032:SULKU_RS11440
uniprot id: E4TX69
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

709032:SULKU RS00115
gene id: 709032:SULKU_RS00115
uniprot id: E4TW75
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

709032:SULKU RS10215
gene id: 709032:SULKU_RS10215
uniprot id: E4U2K5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

709032:SULKU RS06295
gene id: 709032:SULKU_RS06295
uniprot id: E4TXK1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS03345
gene id: 709032:SULKU_RS03345
uniprot id: E4U0V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

709032:SULKU RS09690
gene id: 709032:SULKU_RS09690
uniprot id: E4U235
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

709032:SULKU RS11545
gene id: 709032:SULKU_RS11545
uniprot id: E4TX86
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

709032:SULKU RS06355
gene id: 709032:SULKU_RS06355
uniprot id: E4TXL3
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS02405
gene id: 709032:SULKU_RS02405
uniprot id: E4TZX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

709032:SULKU RS11515
gene id: 709032:SULKU_RS11515
uniprot id: E4TX80
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

709032:SULKU RS03605
gene id: 709032:SULKU_RS03605
uniprot id: E4U172
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS13360
gene id: 709032:SULKU_RS13360
uniprot id: E4U3N5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS07285
gene id: 709032:SULKU_RS07285
uniprot id: E4TZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

709032:SULKU RS06265
gene id: 709032:SULKU_RS06265
uniprot id: E4TXJ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS02515
gene id: 709032:SULKU_RS02515
uniprot id: E4TZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

709032:SULKU RS13945
gene id: 709032:SULKU_RS13945
uniprot id: E4U407
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

709032:SULKU RS08685
gene id: 709032:SULKU_RS08685
uniprot id: E4U0Z0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

709032:SULKU RS01395
gene id: 709032:SULKU_RS01395
uniprot id: E4TYG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS09815
gene id: 709032:SULKU_RS09815
uniprot id: E4U253
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

709032:SULKU RS04980
gene id: 709032:SULKU_RS04980
uniprot id: E4U2R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

709032:SULKU RS05890
gene id: 709032:SULKU_RS05890
uniprot id: E4TWZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS12970
gene id: 709032:SULKU_RS12970
uniprot id: E4U3G2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

709032:SULKU RS07630
gene id: 709032:SULKU_RS07630
uniprot id: E4TZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

709032:SULKU RS10320
gene id: 709032:SULKU_RS10320
uniprot id: E4U2U9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

709032:SULKU RS04070
gene id: 709032:SULKU_RS04070
uniprot id: E4U1U7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS08005
gene id: 709032:SULKU_RS08005
uniprot id: E4U064
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

709032:SULKU RS11775
gene id: 709032:SULKU_RS11775
uniprot id: E4TXR3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

709032:SULKU RS04705
gene id: 709032:SULKU_RS04705
uniprot id: E4U2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

709032:SULKU RS11925
gene id: 709032:SULKU_RS11925
uniprot id: E4TXU4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS11290
gene id: 709032:SULKU_RS11290
uniprot id: E4TX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

709032:SULKU RS03680
gene id: 709032:SULKU_RS03680
uniprot id: E4U187
names: Similarity
messages: Belongs to the YkuD family.

709032:SULKU RS01050
gene id: 709032:SULKU_RS01050
uniprot id: E4TXV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

709032:SULKU RS07920
gene id: 709032:SULKU_RS07920
uniprot id: E4U047
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

709032:SULKU RS05885
gene id: 709032:SULKU_RS05885
uniprot id: E4TWZ0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

709032:SULKU RS09685
gene id: 709032:SULKU_RS09685
uniprot id: E4U234
names: Similarity
messages: Belongs to the ClpA/ClpB family.

709032:SULKU RS06235
gene id: 709032:SULKU_RS06235
uniprot id: E4TXI9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

709032:SULKU RS11060
gene id: 709032:SULKU_RS11060
uniprot id: E4TWL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

709032:SULKU RS07945
gene id: 709032:SULKU_RS07945
uniprot id: E4U052
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

709032:SULKU RS02060
gene id: 709032:SULKU_RS02060
uniprot id: E4TZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

709032:SULKU RS10025
gene id: 709032:SULKU_RS10025
uniprot id: E4U2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

709032:SULKU RS09240
gene id: 709032:SULKU_RS09240
uniprot id: E4U1M9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

709032:SULKU RS13965
gene id: 709032:SULKU_RS13965
uniprot id: E4U411
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

709032:SULKU RS07040
gene id: 709032:SULKU_RS07040
uniprot id: E4TYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS00210
gene id: 709032:SULKU_RS00210
uniprot id: E4TW95
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

709032:SULKU RS09230
gene id: 709032:SULKU_RS09230
uniprot id: E4U1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

709032:SULKU RS05815
gene id: 709032:SULKU_RS05815
uniprot id: E4TWX6
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS03700
gene id: 709032:SULKU_RS03700
uniprot id: E4U191
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

709032:SULKU RS05820
gene id: 709032:SULKU_RS05820
uniprot id: E4TWX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

709032:SULKU RS12670
gene id: 709032:SULKU_RS12670
uniprot id: E4TZE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS02850
gene id: 709032:SULKU_RS02850
uniprot id: E4U0D1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

709032:SULKU RS12375
gene id: 709032:SULKU_RS12375
uniprot id: E4TYV5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS04300
gene id: 709032:SULKU_RS04300
uniprot id: E4U1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

709032:SULKU RS02350
gene id: 709032:SULKU_RS02350
uniprot id: E4TZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

709032:SULKU RS04365
gene id: 709032:SULKU_RS04365
uniprot id: E4U208
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

709032:SULKU RS04385
gene id: 709032:SULKU_RS04385
uniprot id: E4U280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

709032:SULKU RS12725
gene id: 709032:SULKU_RS12725
uniprot id: E4TZF3
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

709032:SULKU RS04975
gene id: 709032:SULKU_RS04975
uniprot id: E4U2R2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

709032:SULKU RS10255
gene id: 709032:SULKU_RS10255
uniprot id: E4U2L3
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS02440
gene id: 709032:SULKU_RS02440
uniprot id: E4TZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

709032:SULKU RS00340
gene id: 709032:SULKU_RS00340
uniprot id: E4TWC1
names: Similarity
messages: Belongs to the UPF0234 family.

709032:SULKU RS12795
gene id: 709032:SULKU_RS12795
uniprot id: E4TZG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

709032:SULKU RS07000
gene id: 709032:SULKU_RS07000
uniprot id: E4TYR0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

709032:SULKU RS02825
gene id: 709032:SULKU_RS02825
uniprot id: E4U0C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

709032:SULKU RS00385
gene id: 709032:SULKU_RS00385
uniprot id: E4TWR6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

709032:SULKU RS00305
gene id: 709032:SULKU_RS00305
uniprot id: E4TWB4
names: Similarity
messages: Belongs to the nitroreductase family.

709032:SULKU RS02445
gene id: 709032:SULKU_RS02445
uniprot id: E4TZY3
names: Similarity
messages: Belongs to the LOG family.

709032:SULKU RS00920
gene id: 709032:SULKU_RS00920
uniprot id: E4TXE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

709032:SULKU RS10150
gene id: 709032:SULKU_RS10150
uniprot id: E4U2J2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

709032:SULKU RS04510
gene id: 709032:SULKU_RS04510
uniprot id: E4U2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

709032:SULKU RS05725
gene id: 709032:SULKU_RS05725
uniprot id: E4TWI1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

709032:SULKU RS03860
gene id: 709032:SULKU_RS03860
uniprot id: E4U1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

709032:SULKU RS01005
gene id: 709032:SULKU_RS01005
uniprot id: E4TXG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

709032:SULKU RS09415
gene id: 709032:SULKU_RS09415
uniprot id: E4U1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS11620
gene id: 709032:SULKU_RS11620
uniprot id: E4TXA2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

709032:SULKU RS04600
gene id: 709032:SULKU_RS04600
uniprot id: E4U2C2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS06505
gene id: 709032:SULKU_RS06505
uniprot id: E4TY32
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

709032:SULKU RS01430
gene id: 709032:SULKU_RS01430
uniprot id: E4TYH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS00780
gene id: 709032:SULKU_RS00780
uniprot id: E4TXC0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

709032:SULKU RS04320
gene id: 709032:SULKU_RS04320
uniprot id: E4U1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS12710
gene id: 709032:SULKU_RS12710
uniprot id: E4TZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

709032:SULKU RS00630
gene id: 709032:SULKU_RS00630
uniprot id: E4TWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

709032:SULKU RS13120
gene id: 709032:SULKU_RS13120
uniprot id: E4U3J0
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS03855
gene id: 709032:SULKU_RS03855
uniprot id: E4U1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS04750
gene id: 709032:SULKU_RS04750
uniprot id: E4U2L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS02765
gene id: 709032:SULKU_RS02765
uniprot id: E4U0B4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

709032:SULKU RS08825
gene id: 709032:SULKU_RS08825
uniprot id: E4U117
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

709032:SULKU RS01870
gene id: 709032:SULKU_RS01870
uniprot id: E4TZ33
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

709032:SULKU RS06925
gene id: 709032:SULKU_RS06925
uniprot id: E4TYP5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

709032:SULKU RS04020
gene id: 709032:SULKU_RS04020
uniprot id: E4U1L9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

709032:SULKU RS01605
gene id: 709032:SULKU_RS01605
uniprot id: E4TYK4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

709032:SULKU RS02570
gene id: 709032:SULKU_RS02570
uniprot id: E4U008
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

709032:SULKU RS03705
gene id: 709032:SULKU_RS03705
uniprot id: E4U192
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

709032:SULKU RS03000
gene id: 709032:SULKU_RS03000
uniprot id: E4U0G3
names: Similarity
messages: Belongs to the DprA/Smf family.

709032:SULKU RS01475
gene id: 709032:SULKU_RS01475
uniprot id: E4TYH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS09255
gene id: 709032:SULKU_RS09255
uniprot id: E4U1N2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS09665
gene id: 709032:SULKU_RS09665
uniprot id: E4U230
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

709032:SULKU RS07485
gene id: 709032:SULKU_RS07485
uniprot id: E4TZD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

709032:SULKU RS00275
gene id: 709032:SULKU_RS00275
uniprot id: E4TWA8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

709032:SULKU RS02460
gene id: 709032:SULKU_RS02460
uniprot id: E4TZY6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

709032:SULKU RS08895
gene id: 709032:SULKU_RS08895
uniprot id: E4U196
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS13205
gene id: 709032:SULKU_RS13205
uniprot id: E4U3K8
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01785
gene id: 709032:SULKU_RS01785
uniprot id: E4TZ17
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS07270
gene id: 709032:SULKU_RS07270
uniprot id: E4TZ91
names: Similarity
messages: Belongs to the MQO family.

709032:SULKU RS10915
gene id: 709032:SULKU_RS10915
uniprot id: E4U3D2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

709032:SULKU RS10310
gene id: 709032:SULKU_RS10310
uniprot id: E4U2U7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

709032:SULKU RS01985
gene id: 709032:SULKU_RS01985
uniprot id: E4TZ56
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

709032:SULKU RS09620
gene id: 709032:SULKU_RS09620
uniprot id: E4U221
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

709032:SULKU RS04745
gene id: 709032:SULKU_RS04745
uniprot id: E4U2L6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS04325
gene id: 709032:SULKU_RS04325
uniprot id: E4U200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

709032:SULKU RS10980
gene id: 709032:SULKU_RS10980
uniprot id: E4TWJ6
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS07495
gene id: 709032:SULKU_RS07495
uniprot id: E4TZP3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

709032:SULKU RS06130
gene id: 709032:SULKU_RS06130
uniprot id: E4TXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS10495
gene id: 709032:SULKU_RS10495
uniprot id: E4U2Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS12660
gene id: 709032:SULKU_RS12660
uniprot id: E4TZE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS05580
gene id: 709032:SULKU_RS05580
uniprot id: E4TWF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS07245
gene id: 709032:SULKU_RS07245
uniprot id: E4TZ86
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

709032:SULKU RS11780
gene id: 709032:SULKU_RS11780
uniprot id: E4TXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

709032:SULKU RS10555
gene id: 709032:SULKU_RS10555
uniprot id: E4U2Z3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS03765
gene id: 709032:SULKU_RS03765
uniprot id: E4U1H2
names: Similarity
messages: Belongs to the RutC family.

709032:SULKU RS03615
gene id: 709032:SULKU_RS03615
uniprot id: E4U174
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

709032:SULKU RS03445
gene id: 709032:SULKU_RS03445
uniprot id: E4U140
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

709032:SULKU RS11995
gene id: 709032:SULKU_RS11995
uniprot id: E4TY99
names: Similarity
messages: Belongs to the asparagine synthetase family.

709032:SULKU RS03820
gene id: 709032:SULKU_RS03820
uniprot id: E4U1I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

709032:SULKU RS11605
gene id: 709032:SULKU_RS11605
uniprot id: E4TX99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

709032:SULKU RS01000
gene id: 709032:SULKU_RS01000
uniprot id: E4TXG4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

709032:SULKU RS05335
gene id: 709032:SULKU_RS05335
uniprot id: E4U350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

709032:SULKU RS07015
gene id: 709032:SULKU_RS07015
uniprot id: E4TYR3
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS03555
gene id: 709032:SULKU_RS03555
uniprot id: E4U162
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

709032:SULKU RS09700
gene id: 709032:SULKU_RS09700
uniprot id: E4U237
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06460
gene id: 709032:SULKU_RS06460
uniprot id: E4TY23
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

709032:SULKU RS05595
gene id: 709032:SULKU_RS05595
uniprot id: E4TWF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

709032:SULKU RS11375
gene id: 709032:SULKU_RS11375
uniprot id: E4TX56
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS04160
gene id: 709032:SULKU_RS04160
uniprot id: E4U1W5
names: Similarity
messages: Belongs to the TlyA family.

709032:SULKU RS02485
gene id: 709032:SULKU_RS02485
uniprot id: E4TZZ1
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS11830
gene id: 709032:SULKU_RS11830
uniprot id: E4TXS5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

709032:SULKU RS13380
gene id: 709032:SULKU_RS13380
uniprot id: E4U3N9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS05590
gene id: 709032:SULKU_RS05590
uniprot id: E4TWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

709032:SULKU RS02070
gene id: 709032:SULKU_RS02070
uniprot id: E4TZI4
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS06190
gene id: 709032:SULKU_RS06190
uniprot id: E4TXI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

709032:SULKU RS05045
gene id: 709032:SULKU_RS05045
uniprot id: E4U2S5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

709032:SULKU RS14170
gene id: 709032:SULKU_RS14170
uniprot id: E4TXF4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

709032:SULKU RS00595
gene id: 709032:SULKU_RS00595
uniprot id: E4TWV5
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

709032:SULKU RS03630
gene id: 709032:SULKU_RS03630
uniprot id: E4U177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

709032:SULKU RS04430
gene id: 709032:SULKU_RS04430
uniprot id: E4U289
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

709032:SULKU RS01015
gene id: 709032:SULKU_RS01015
uniprot id: E4TXG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

709032:SULKU RS02945
gene id: 709032:SULKU_RS02945
uniprot id: E4U0F2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06610
gene id: 709032:SULKU_RS06610
uniprot id: E4TY53
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

709032:SULKU RS04950
gene id: 709032:SULKU_RS04950
uniprot id: E4U2Q7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS10455
gene id: 709032:SULKU_RS10455
uniprot id: E4U2X5
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS03285
gene id: 709032:SULKU_RS03285
uniprot id: E4U0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

709032:SULKU RS11985
gene id: 709032:SULKU_RS11985
uniprot id: E4TY97
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

709032:SULKU RS02345
gene id: 709032:SULKU_RS02345
uniprot id: E4TZP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

709032:SULKU RS09410
gene id: 709032:SULKU_RS09410
uniprot id: E4U1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS11020
gene id: 709032:SULKU_RS11020
uniprot id: E4TWK5
names: Similarity
messages: Belongs to the glutamine synthetase family.

709032:SULKU RS06650
gene id: 709032:SULKU_RS06650
uniprot id: E4TY61
names: Similarity
messages: Belongs to the MEMO1 family.

709032:SULKU RS05740
gene id: 709032:SULKU_RS05740
uniprot id: E4TWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

709032:SULKU RS13090
gene id: 709032:SULKU_RS13090
uniprot id: E4U3I4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

709032:SULKU RS03495
gene id: 709032:SULKU_RS03495
uniprot id: E4U150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

709032:SULKU RS02580
gene id: 709032:SULKU_RS02580
uniprot id: E4U010
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

709032:SULKU RS01060
gene id: 709032:SULKU_RS01060
uniprot id: E4TXW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

709032:SULKU RS09460
gene id: 709032:SULKU_RS09460
uniprot id: E4U1S3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

709032:SULKU RS02295
gene id: 709032:SULKU_RS02295
uniprot id: E4TZM9
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS07265
gene id: 709032:SULKU_RS07265
uniprot id: E4TZ90
names: Similarity
messages: Belongs to the citrate synthase family.

709032:SULKU RS01715
gene id: 709032:SULKU_RS01715
uniprot id: E4TZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

709032:SULKU RS01905
gene id: 709032:SULKU_RS01905
uniprot id: E4TZ40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

709032:SULKU RS07935
gene id: 709032:SULKU_RS07935
uniprot id: E4U050
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

709032:SULKU RS13920
gene id: 709032:SULKU_RS13920
uniprot id: E4U401
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

709032:SULKU RS02375
gene id: 709032:SULKU_RS02375
uniprot id: E4TZW9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

709032:SULKU RS04970
gene id: 709032:SULKU_RS04970
uniprot id: E4U2R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

709032:SULKU RS01325
gene id: 709032:SULKU_RS01325
uniprot id: E4TY13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

709032:SULKU RS03885
gene id: 709032:SULKU_RS03885
uniprot id: E4U1J7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

709032:SULKU RS07775
gene id: 709032:SULKU_RS07775
uniprot id: E4TZU9
names: Similarity
messages: Belongs to the ArsC family.

709032:SULKU RS11965
gene id: 709032:SULKU_RS11965
uniprot id: E4TXV2
names: Similarity
messages: Belongs to the AdoMet synthase family.

709032:SULKU RS07370
gene id: 709032:SULKU_RS07370
uniprot id: E4TZB1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

709032:SULKU RS05795
gene id: 709032:SULKU_RS05795
uniprot id: E4TWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS09365
gene id: 709032:SULKU_RS09365
uniprot id: E4U1Q4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

709032:SULKU RS01950
gene id: 709032:SULKU_RS01950
uniprot id: E4TZ49
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

709032:SULKU RS13425
gene id: 709032:SULKU_RS13425
uniprot id: E4U3Q0
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS03625
gene id: 709032:SULKU_RS03625
uniprot id: E4U176
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

709032:SULKU RS10925
gene id: 709032:SULKU_RS10925
uniprot id: E4U3D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

709032:SULKU RS09300
gene id: 709032:SULKU_RS09300
uniprot id: E4U1P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

709032:SULKU RS12665
gene id: 709032:SULKU_RS12665
uniprot id: E4TZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

709032:SULKU RS01415
gene id: 709032:SULKU_RS01415
uniprot id: E4TYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

709032:SULKU RS01210
gene id: 709032:SULKU_RS01210
uniprot id: E4TXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

709032:SULKU RS00540
gene id: 709032:SULKU_RS00540
uniprot id: E4TWU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS14655
gene id: 709032:SULKU_RS14655
uniprot id: E4U3P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

709032:SULKU RS10220
gene id: 709032:SULKU_RS10220
uniprot id: E4U2K6
names: Similarity
messages: Belongs to the HypE family.

709032:SULKU RS08695
gene id: 709032:SULKU_RS08695
uniprot id: E4U0Z1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS04865
gene id: 709032:SULKU_RS04865
uniprot id: E4U2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS04035
gene id: 709032:SULKU_RS04035
uniprot id: E4U1M2
names: Similarity
messages: Belongs to the XseB family.

709032:SULKU RS01885
gene id: 709032:SULKU_RS01885
uniprot id: E4TZ36
names: Similarity
messages: Belongs to the TrpF family.

709032:SULKU RS03205
gene id: 709032:SULKU_RS03205
uniprot id: E4U0S5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS10670
gene id: 709032:SULKU_RS10670
uniprot id: E4U383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

709032:SULKU RS07640
gene id: 709032:SULKU_RS07640
uniprot id: E4TZS2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

709032:SULKU RS12380
gene id: 709032:SULKU_RS12380
uniprot id: E4TYV6
names: Similarity
messages: Belongs to the ArsC family.

709032:SULKU RS09220
gene id: 709032:SULKU_RS09220
uniprot id: E4U1G1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

709032:SULKU RS01700
gene id: 709032:SULKU_RS01700
uniprot id: E4TZ02
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09500
gene id: 709032:SULKU_RS09500
uniprot id: E4U1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

709032:SULKU RS00870
gene id: 709032:SULKU_RS00870
uniprot id: E4TXD8
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS09995
gene id: 709032:SULKU_RS09995
uniprot id: E4U2F8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

709032:SULKU RS12720
gene id: 709032:SULKU_RS12720
uniprot id: E4TZF2
names: Similarity
messages: Belongs to the PhoH family.

709032:SULKU RS02355
gene id: 709032:SULKU_RS02355
uniprot id: E4TZW5
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

709032:SULKU RS01965
gene id: 709032:SULKU_RS01965
uniprot id: E4TZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

709032:SULKU RS03030
gene id: 709032:SULKU_RS03030
uniprot id: E4U0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

709032:SULKU RS11760
gene id: 709032:SULKU_RS11760
uniprot id: E4TXR0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS02610
gene id: 709032:SULKU_RS02610
uniprot id: E4U016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Membrane

709032:SULKU RS04830
gene id: 709032:SULKU_RS04830
uniprot id: E4U2N3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

709032:SULKU RS00575
gene id: 709032:SULKU_RS00575
uniprot id: E4TWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

709032:SULKU RS03595
gene id: 709032:SULKU_RS03595
uniprot id: E4U170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

709032:SULKU RS00170
gene id: 709032:SULKU_RS00170
uniprot id: E4TW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS03785
gene id: 709032:SULKU_RS03785
uniprot id: E4U1H7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

709032:SULKU RS04185
gene id: 709032:SULKU_RS04185
uniprot id: E4U1X0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

709032:SULKU RS01485
gene id: 709032:SULKU_RS01485
uniprot id: E4TYI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

709032:SULKU RS11860
gene id: 709032:SULKU_RS11860
uniprot id: E4TXT1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

709032:SULKU RS03460
gene id: 709032:SULKU_RS03460
uniprot id: E4U143
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00705
gene id: 709032:SULKU_RS00705
uniprot id: E4TXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

709032:SULKU RS03790
gene id: 709032:SULKU_RS03790
uniprot id: E4U1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS14010
gene id: 709032:SULKU_RS14010
uniprot id: E4U420
names: Similarity
messages: Belongs to the transposase 7 family.

709032:SULKU RS03315
gene id: 709032:SULKU_RS03315
uniprot id: E4U0U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

709032:SULKU RS14490
gene id: 709032:SULKU_RS14490
uniprot id: E4U0L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01940
gene id: 709032:SULKU_RS01940
uniprot id: E4TZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

709032:SULKU RS07025
gene id: 709032:SULKU_RS07025
uniprot id: E4TYR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

709032:SULKU RS03070
gene id: 709032:SULKU_RS03070
uniprot id: E4U0P8
names: Similarity
messages: Belongs to the MotB family.

709032:SULKU RS12750
gene id: 709032:SULKU_RS12750
uniprot id: E4TZF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

709032:SULKU RS03065
gene id: 709032:SULKU_RS03065
uniprot id: E4U0P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS04315
gene id: 709032:SULKU_RS04315
uniprot id: E4U1Z8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

709032:SULKU RS10695
gene id: 709032:SULKU_RS10695
uniprot id: E4U387
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

709032:SULKU RS03795
gene id: 709032:SULKU_RS03795
uniprot id: E4U1H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

709032:SULKU RS09900
gene id: 709032:SULKU_RS09900
uniprot id: E4U270
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

709032:SULKU RS01030
gene id: 709032:SULKU_RS01030
uniprot id: E4TXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

709032:SULKU RS10975
gene id: 709032:SULKU_RS10975
uniprot id: E4TWJ5
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS05280
gene id: 709032:SULKU_RS05280
uniprot id: E4U339
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

709032:SULKU RS04310
gene id: 709032:SULKU_RS04310
uniprot id: E4U1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS06405
gene id: 709032:SULKU_RS06405
uniprot id: E4TXM3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

709032:SULKU RS04645
gene id: 709032:SULKU_RS04645
uniprot id: E4U2D1
names: Similarity
messages: Belongs to the UPF0178 family.

709032:SULKU RS02235
gene id: 709032:SULKU_RS02235
uniprot id: E4TZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

709032:SULKU RS10425
gene id: 709032:SULKU_RS10425
uniprot id: E4U2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

709032:SULKU RS01305
gene id: 709032:SULKU_RS01305
uniprot id: E4TY09
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

709032:SULKU RS09495
gene id: 709032:SULKU_RS09495
uniprot id: E4U1T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

709032:SULKU RS07930
gene id: 709032:SULKU_RS07930
uniprot id: E4U049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS11595
gene id: 709032:SULKU_RS11595
uniprot id: E4TX97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

709032:SULKU RS07545
gene id: 709032:SULKU_RS07545
uniprot id: E4TZQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

709032:SULKU RS01560
gene id: 709032:SULKU_RS01560
uniprot id: E4TYJ5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

709032:SULKU RS04595
gene id: 709032:SULKU_RS04595
uniprot id: E4U2C1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS12145
gene id: 709032:SULKU_RS12145
uniprot id: E4TYC9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

709032:SULKU RS11970
gene id: 709032:SULKU_RS11970
uniprot id: E4TY94
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

709032:SULKU RS05970
gene id: 709032:SULKU_RS05970
uniprot id: E4TX07
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

709032:SULKU RS04500
gene id: 709032:SULKU_RS04500
uniprot id: E4U2A3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS07085
gene id: 709032:SULKU_RS07085
uniprot id: E4TYS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS11930
gene id: 709032:SULKU_RS11930
uniprot id: E4TXU5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

709032:SULKU RS14520
gene id: 709032:SULKU_RS14520
uniprot id: E4U1B6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

709032:SULKU RS02000
gene id: 709032:SULKU_RS02000
uniprot id: E4TZ59
names: Similarity
messages: Belongs to the peptidase S41A family.

709032:SULKU RS04565
gene id: 709032:SULKU_RS04565
uniprot id: E4U2B6
names: Similarity
messages: Belongs to the UPF0045 family.

709032:SULKU RS00515
gene id: 709032:SULKU_RS00515
uniprot id: E4TWU0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

709032:SULKU RS01400
gene id: 709032:SULKU_RS01400
uniprot id: E4TYG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS02650
gene id: 709032:SULKU_RS02650
uniprot id: E4U024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

709032:SULKU RS03080
gene id: 709032:SULKU_RS03080
uniprot id: E4U0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

709032:SULKU RS05065
gene id: 709032:SULKU_RS05065
uniprot id: E4U2T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS12860
gene id: 709032:SULKU_RS12860
uniprot id: E4TZH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

709032:SULKU RS02655
gene id: 709032:SULKU_RS02655
uniprot id: E4U025
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

709032:SULKU RS08020
gene id: 709032:SULKU_RS08020
uniprot id: E4U068
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

709032:SULKU RS06955
gene id: 709032:SULKU_RS06955
uniprot id: E4TYQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

709032:SULKU RS05870
gene id: 709032:SULKU_RS05870
uniprot id: E4TWY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS00025
gene id: 709032:SULKU_RS00025
uniprot id: E4TW57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS07955
gene id: 709032:SULKU_RS07955
uniprot id: E4U054
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

709032:SULKU RS06435
gene id: 709032:SULKU_RS06435
uniprot id: E4TXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Homopentamer. In the absence of Mg(2+), interactions between subunits are weakened, and dimers, trimers and tetramers can be observed in vitro.
messages: Mediates influx of magnesium ions.
messages: Membrane

709032:SULKU RS01250
gene id: 709032:SULKU_RS01250
uniprot id: E4TXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

709032:SULKU RS12410
gene id: 709032:SULKU_RS12410
uniprot id: E4TYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS02900
gene id: 709032:SULKU_RS02900
uniprot id: E4U0E1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

709032:SULKU RS01890
gene id: 709032:SULKU_RS01890
uniprot id: E4TZ37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

709032:SULKU RS01020
gene id: 709032:SULKU_RS01020
uniprot id: E4TXG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

709032:SULKU RS03685
gene id: 709032:SULKU_RS03685
uniprot id: E4U188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

709032:SULKU RS11885
gene id: 709032:SULKU_RS11885
uniprot id: E4TXT6
names: Similarity
messages: Belongs to the MotB family.

709032:SULKU RS01915
gene id: 709032:SULKU_RS01915
uniprot id: E4TZ42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

709032:SULKU RS00175
gene id: 709032:SULKU_RS00175
uniprot id: E4TW88
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS02455
gene id: 709032:SULKU_RS02455
uniprot id: E4TZY5
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS10790
gene id: 709032:SULKU_RS10790
uniprot id: E4U3A6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

709032:SULKU RS02785
gene id: 709032:SULKU_RS02785
uniprot id: E4U0B8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

709032:SULKU RS06005
gene id: 709032:SULKU_RS06005
uniprot id: E4TX13
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

709032:SULKU RS11490
gene id: 709032:SULKU_RS11490
uniprot id: E4TX75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Homopentamer. In the absence of Mg(2+), interactions between subunits are weakened, and dimers, trimers and tetramers can be observed in vitro.
messages: Mediates influx of magnesium ions.
messages: Membrane

709032:SULKU RS00375
gene id: 709032:SULKU_RS00375
uniprot id: E4TWR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

709032:SULKU RS12275
gene id: 709032:SULKU_RS12275
uniprot id: E4TYE9
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

709032:SULKU RS06525
gene id: 709032:SULKU_RS06525
uniprot id: E4TY36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

709032:SULKU RS07350
gene id: 709032:SULKU_RS07350
uniprot id: E4TZA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

709032:SULKU RS12140
gene id: 709032:SULKU_RS12140
uniprot id: E4TYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

709032:SULKU RS07950
gene id: 709032:SULKU_RS07950
uniprot id: E4U053
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

709032:SULKU RS04445
gene id: 709032:SULKU_RS04445
uniprot id: E4U292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

709032:SULKU RS13095
gene id: 709032:SULKU_RS13095
uniprot id: E4U3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS04370
gene id: 709032:SULKU_RS04370
uniprot id: E4U209
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

709032:SULKU RS12640
gene id: 709032:SULKU_RS12640
uniprot id: E4TZD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS03100
gene id: 709032:SULKU_RS03100
uniprot id: E4U0Q4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

709032:SULKU RS08890
gene id: 709032:SULKU_RS08890
uniprot id: E4U130
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS00510
gene id: 709032:SULKU_RS00510
uniprot id: E4TWT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00995
gene id: 709032:SULKU_RS00995
uniprot id: E4TXG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

709032:SULKU RS04470
gene id: 709032:SULKU_RS04470
uniprot id: E4U297
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

709032:SULKU RS06375
gene id: 709032:SULKU_RS06375
uniprot id: E4TXL7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

709032:SULKU RS11425
gene id: 709032:SULKU_RS11425
uniprot id: E4TX66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

709032:SULKU RS10460
gene id: 709032:SULKU_RS10460
uniprot id: E4U2X6
names: Similarity
messages: Belongs to the P(II) protein family.

709032:SULKU RS10370
gene id: 709032:SULKU_RS10370
uniprot id: E4U2V9
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS04030
gene id: 709032:SULKU_RS04030
uniprot id: E4U1M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

709032:SULKU RS02325
gene id: 709032:SULKU_RS02325
uniprot id: E4TZN5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

709032:SULKU RS10995
gene id: 709032:SULKU_RS10995
uniprot id: E4TWK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

709032:SULKU RS05255
gene id: 709032:SULKU_RS05255
uniprot id: E4U334
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS04410
gene id: 709032:SULKU_RS04410
uniprot id: E4U285
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

709032:SULKU RS02795
gene id: 709032:SULKU_RS02795
uniprot id: E4U0C0
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS09435
gene id: 709032:SULKU_RS09435
uniprot id: E4U1R8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06390
gene id: 709032:SULKU_RS06390
uniprot id: E4TXM0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

709032:SULKU RS01085
gene id: 709032:SULKU_RS01085
uniprot id: E4TXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

709032:SULKU RS04200
gene id: 709032:SULKU_RS04200
uniprot id: E4U1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

709032:SULKU RS12225
gene id: 709032:SULKU_RS12225
uniprot id: E4TYD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

709032:SULKU RS08255
gene id: 709032:SULKU_RS08255
uniprot id: E4U0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

709032:SULKU RS08850
gene id: 709032:SULKU_RS08850
uniprot id: E4U122
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

709032:SULKU RS02245
gene id: 709032:SULKU_RS02245
uniprot id: E4TZL9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

709032:SULKU RS13430
gene id: 709032:SULKU_RS13430
uniprot id: E4U3Q1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS12830
gene id: 709032:SULKU_RS12830
uniprot id: E4TZH4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

709032:SULKU RS12480
gene id: 709032:SULKU_RS12480
uniprot id: E4TYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

709032:SULKU RS07770
gene id: 709032:SULKU_RS07770
uniprot id: E4TZU8
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS12570
gene id: 709032:SULKU_RS12570
uniprot id: E4TYZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

709032:SULKU RS08135
gene id: 709032:SULKU_RS08135
uniprot id: E4U092
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

709032:SULKU RS06030
gene id: 709032:SULKU_RS06030
uniprot id: E4TX18
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS01390
gene id: 709032:SULKU_RS01390
uniprot id: E4TYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

709032:SULKU RS08130
gene id: 709032:SULKU_RS08130
uniprot id: E4U091
names: Similarity
messages: Belongs to the DNA photolyase family.

709032:SULKU RS00195
gene id: 709032:SULKU_RS00195
uniprot id: E4TW92
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

709032:SULKU RS01080
gene id: 709032:SULKU_RS01080
uniprot id: E4TXW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

709032:SULKU RS03510
gene id: 709032:SULKU_RS03510
uniprot id: E4U153
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

709032:SULKU RS02565
gene id: 709032:SULKU_RS02565
uniprot id: E4U007
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

709032:SULKU RS09350
gene id: 709032:SULKU_RS09350
uniprot id: E4U1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

709032:SULKU RS11305
gene id: 709032:SULKU_RS11305
uniprot id: E4TX42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

709032:SULKU RS00015
gene id: 709032:SULKU_RS00015
uniprot id: E4TW55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

709032:SULKU RS00555
gene id: 709032:SULKU_RS00555
uniprot id: E4TWU7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

709032:SULKU RS06280
gene id: 709032:SULKU_RS06280
uniprot id: E4TXJ8
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS09515
gene id: 709032:SULKU_RS09515
uniprot id: E4U1T4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

709032:SULKU RS03720
gene id: 709032:SULKU_RS03720
uniprot id: E4U195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

709032:SULKU RS04685
gene id: 709032:SULKU_RS04685
uniprot id: E4U2D9
names: Similarity
messages: Belongs to the peptidase M18 family.

709032:SULKU RS07365
gene id: 709032:SULKU_RS07365
uniprot id: E4TZB0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

709032:SULKU RS11865
gene id: 709032:SULKU_RS11865
uniprot id: E4TXT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

709032:SULKU RS10405
gene id: 709032:SULKU_RS10405
uniprot id: E4U2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

709032:SULKU RS03635
gene id: 709032:SULKU_RS03635
uniprot id: E4U178
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS04305
gene id: 709032:SULKU_RS04305
uniprot id: E4U1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS06160
gene id: 709032:SULKU_RS06160
uniprot id: E4TXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

709032:SULKU RS06440
gene id: 709032:SULKU_RS06440
uniprot id: E4TXN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

709032:SULKU RS06545
gene id: 709032:SULKU_RS06545
uniprot id: E4TY40
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

709032:SULKU RS10285
gene id: 709032:SULKU_RS10285
uniprot id: E4U2U2
names: Similarity
messages: Belongs to the peptidase A31 family.

709032:SULKU RS05675
gene id: 709032:SULKU_RS05675
uniprot id: E4TWH1
names: Similarity
messages: Belongs to the glutamate synthase family.

709032:SULKU RS02935
gene id: 709032:SULKU_RS02935
uniprot id: E4U0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

709032:SULKU RS10505
gene id: 709032:SULKU_RS10505
uniprot id: E4U2Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS06885
gene id: 709032:SULKU_RS06885
uniprot id: E4TYN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

709032:SULKU RS05320
gene id: 709032:SULKU_RS05320
uniprot id: E4U347
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

709032:SULKU RS10265
gene id: 709032:SULKU_RS10265
uniprot id: E4U2T8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

709032:SULKU RS07905
gene id: 709032:SULKU_RS07905
uniprot id: E4U044
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

709032:SULKU RS00520
gene id: 709032:SULKU_RS00520
uniprot id: E4TWU1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

709032:SULKU RS04875
gene id: 709032:SULKU_RS04875
uniprot id: E4U2P2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

709032:SULKU RS04935
gene id: 709032:SULKU_RS04935
uniprot id: E4U2Q4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

709032:SULKU RS01865
gene id: 709032:SULKU_RS01865
uniprot id: E4TZ32
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

709032:SULKU RS05565
gene id: 709032:SULKU_RS05565
uniprot id: E4TWE9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

709032:SULKU RS02540
gene id: 709032:SULKU_RS02540
uniprot id: E4U002
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

709032:SULKU RS00150
gene id: 709032:SULKU_RS00150
uniprot id: E4TW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

709032:SULKU RS05945
gene id: 709032:SULKU_RS05945
uniprot id: E4TX02
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

709032:SULKU RS06285
gene id: 709032:SULKU_RS06285
uniprot id: E4TXJ9
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01470
gene id: 709032:SULKU_RS01470
uniprot id: E4TYH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

709032:SULKU RS00855
gene id: 709032:SULKU_RS00855
uniprot id: E4TXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

709032:SULKU RS03780
gene id: 709032:SULKU_RS03780
uniprot id: E4U1H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

709032:SULKU RS13910
gene id: 709032:SULKU_RS13910
uniprot id: E4U3Z9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.
messages: Belongs to the type-I restriction system S methylase family.

709032:SULKU RS00345
gene id: 709032:SULKU_RS00345
uniprot id: E4TWQ7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

709032:SULKU RS05330
gene id: 709032:SULKU_RS05330
uniprot id: E4U349
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

709032:SULKU RS04270
gene id: 709032:SULKU_RS04270
uniprot id: E4U1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

709032:SULKU RS00060
gene id: 709032:SULKU_RS00060
uniprot id: E4TW64
names: Similarity
messages: Belongs to the PhoU family.

709032:SULKU RS08250
gene id: 709032:SULKU_RS08250
uniprot id: E4U0I6
names: Similarity
messages: Belongs to the type III secretion exporter family.

709032:SULKU RS01075
gene id: 709032:SULKU_RS01075
uniprot id: E4TXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

709032:SULKU RS00130
gene id: 709032:SULKU_RS00130
uniprot id: E4TW78
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

709032:SULKU RS01150
gene id: 709032:SULKU_RS01150
uniprot id: E4TXX8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00430
gene id: 709032:SULKU_RS00430
uniprot id: E4TWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

709032:SULKU RS06565
gene id: 709032:SULKU_RS06565
uniprot id: E4TY44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

709032:SULKU RS11485
gene id: 709032:SULKU_RS11485
uniprot id: E4TX74
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS02495
gene id: 709032:SULKU_RS02495
uniprot id: E4TZZ3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

709032:SULKU RS06915
gene id: 709032:SULKU_RS06915
uniprot id: E4TYP3
names: Subcellular Location Annotation
messages: Cytoplasm

709032:SULKU RS06860
gene id: 709032:SULKU_RS06860
uniprot id: E4TYN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

709032:SULKU RS12485
gene id: 709032:SULKU_RS12485
uniprot id: E4TYX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

709032:SULKU RS13375
gene id: 709032:SULKU_RS13375
uniprot id: E4U3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS01595
gene id: 709032:SULKU_RS01595
uniprot id: E4TYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

709032:SULKU RS12885
gene id: 709032:SULKU_RS12885
uniprot id: E4U3E3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

709032:SULKU RS02165
gene id: 709032:SULKU_RS02165
uniprot id: E4TZK3
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS01590
gene id: 709032:SULKU_RS01590
uniprot id: E4TYK1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

709032:SULKU RS04115
gene id: 709032:SULKU_RS04115
uniprot id: E4U1V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

709032:SULKU RS07355
gene id: 709032:SULKU_RS07355
uniprot id: E4TZA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

709032:SULKU RS03225
gene id: 709032:SULKU_RS03225
uniprot id: E4U0S9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS01235
gene id: 709032:SULKU_RS01235
uniprot id: E4TXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

709032:SULKU RS01410
gene id: 709032:SULKU_RS01410
uniprot id: E4TYG6
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS11285
gene id: 709032:SULKU_RS11285
uniprot id: E4TX37
names: Similarity
messages: Belongs to the GSP E family.

709032:SULKU RS02545
gene id: 709032:SULKU_RS02545
uniprot id: E4U003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

709032:SULKU RS11960
gene id: 709032:SULKU_RS11960
uniprot id: E4TXV1
names: Similarity
messages: Belongs to the asparagine synthetase family.

709032:SULKU RS01035
gene id: 709032:SULKU_RS01035
uniprot id: E4TXV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

709032:SULKU RS04820
gene id: 709032:SULKU_RS04820
uniprot id: E4U2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

709032:SULKU RS04740
gene id: 709032:SULKU_RS04740
uniprot id: E4U2L5
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS05170
gene id: 709032:SULKU_RS05170
uniprot id: E4U317
names: Similarity
messages: Belongs to the hemerythrin family.

709032:SULKU RS11845
gene id: 709032:SULKU_RS11845
uniprot id: E4TXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS12435
gene id: 709032:SULKU_RS12435
uniprot id: E4TYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS01095
gene id: 709032:SULKU_RS01095
uniprot id: E4TXW7
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

709032:SULKU RS12700
gene id: 709032:SULKU_RS12700
uniprot id: E4TZE8
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS09140
gene id: 709032:SULKU_RS09140
uniprot id: E4U1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

709032:SULKU RS04380
gene id: 709032:SULKU_RS04380
uniprot id: E4U211
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS01360
gene id: 709032:SULKU_RS01360
uniprot id: E4TY20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709032:SULKU RS10365
gene id: 709032:SULKU_RS10365
uniprot id: E4U2V8
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS04760
gene id: 709032:SULKU_RS04760
uniprot id: E4U2L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

709032:SULKU RS02530
gene id: 709032:SULKU_RS02530
uniprot id: E4U000
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

709032:SULKU RS12730
gene id: 709032:SULKU_RS12730
uniprot id: E4TZF4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

709032:SULKU RS10895
gene id: 709032:SULKU_RS10895
uniprot id: E4U3C8
names: Similarity
messages: Belongs to the DEAD box helicase family.

709032:SULKU RS05905
gene id: 709032:SULKU_RS05905
uniprot id: E4TWZ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

709032:SULKU RS02365
gene id: 709032:SULKU_RS02365
uniprot id: E4TZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

709032:SULKU RS11615
gene id: 709032:SULKU_RS11615
uniprot id: E4TXA1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

709032:SULKU RS11420
gene id: 709032:SULKU_RS11420
uniprot id: E4TX65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

709032:SULKU RS11875
gene id: 709032:SULKU_RS11875
uniprot id: E4TXT4
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS01855
gene id: 709032:SULKU_RS01855
uniprot id: E4TZ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

709032:SULKU RS12745
gene id: 709032:SULKU_RS12745
uniprot id: E4TZF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

709032:SULKU RS04730
gene id: 709032:SULKU_RS04730
uniprot id: E4U2E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

709032:SULKU RS11445
gene id: 709032:SULKU_RS11445
uniprot id: E4TX70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

709032:SULKU RS04700
gene id: 709032:SULKU_RS04700
uniprot id: E4U2E2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

709032:SULKU RS05760
gene id: 709032:SULKU_RS05760
uniprot id: E4TWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS07090
gene id: 709032:SULKU_RS07090
uniprot id: E4TYS8
names: Similarity
messages: Belongs to the YggT family.

709032:SULKU RS01860
gene id: 709032:SULKU_RS01860
uniprot id: E4TZ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

709032:SULKU RS06465
gene id: 709032:SULKU_RS06465
uniprot id: E4TY24
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

709032:SULKU RS02615
gene id: 709032:SULKU_RS02615
uniprot id: E4U017
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

709032:SULKU RS10860
gene id: 709032:SULKU_RS10860
uniprot id: E4U3C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

709032:SULKU RS09615
gene id: 709032:SULKU_RS09615
uniprot id: E4U220
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

709032:SULKU RS10845
gene id: 709032:SULKU_RS10845
uniprot id: E4U3B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

709032:SULKU RS00505
gene id: 709032:SULKU_RS00505
uniprot id: E4TWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

709032:SULKU RS08710
gene id: 709032:SULKU_RS08710
uniprot id: E4U0Z4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS10340
gene id: 709032:SULKU_RS10340
uniprot id: E4U2V3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

709032:SULKU RS07020
gene id: 709032:SULKU_RS07020
uniprot id: E4TYR4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

709032:SULKU RS09680
gene id: 709032:SULKU_RS09680
uniprot id: E4U233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

709032:SULKU RS08680
gene id: 709032:SULKU_RS08680
uniprot id: E4U0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

709032:SULKU RS01220
gene id: 709032:SULKU_RS01220
uniprot id: E4TXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

709032:SULKU RS07925
gene id: 709032:SULKU_RS07925
uniprot id: E4U048
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

709032:SULKU RS05100
gene id: 709032:SULKU_RS05100
uniprot id: E4U303
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

709032:SULKU RS01205
gene id: 709032:SULKU_RS01205
uniprot id: E4TXY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

709032:SULKU RS13850
gene id: 709032:SULKU_RS13850
uniprot id: E4U3Y6
names: Similarity
messages: Belongs to the YciI family.

709032:SULKU RS00040
gene id: 709032:SULKU_RS00040
uniprot id: E4TW60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

709032:SULKU RS03035
gene id: 709032:SULKU_RS03035
uniprot id: E4U0H0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

709032:SULKU RS00440
gene id: 709032:SULKU_RS00440
uniprot id: E4TWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

709032:SULKU RS01010
gene id: 709032:SULKU_RS01010
uniprot id: E4TXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

709032:SULKU RS05600
gene id: 709032:SULKU_RS05600
uniprot id: E4TWF6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS07890
gene id: 709032:SULKU_RS07890
uniprot id: E4U041
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

709032:SULKU RS10910
gene id: 709032:SULKU_RS10910
uniprot id: E4U3D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS00245
gene id: 709032:SULKU_RS00245
uniprot id: E4TWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

709032:SULKU RS12125
gene id: 709032:SULKU_RS12125
uniprot id: E4TYC5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

709032:SULKU RS10315
gene id: 709032:SULKU_RS10315
uniprot id: E4U2U8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

709032:SULKU RS09830
gene id: 709032:SULKU_RS09830
uniprot id: E4U256
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

709032:SULKU RS14295
gene id: 709032:SULKU_RS14295
uniprot id: E4U201
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

709032:SULKU RS12685
gene id: 709032:SULKU_RS12685
uniprot id: E4TZE5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS04890
gene id: 709032:SULKU_RS04890
uniprot id: E4U2P5
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

709032:SULKU RS14155
gene id: 709032:SULKU_RS14155
uniprot id: E4TWB1
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS00990
gene id: 709032:SULKU_RS00990
uniprot id: E4TXG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

709032:SULKU RS09475
gene id: 709032:SULKU_RS09475
uniprot id: E4U1S6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS02585
gene id: 709032:SULKU_RS02585
uniprot id: E4U011
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

709032:SULKU RS14260
gene id: 709032:SULKU_RS14260
uniprot id: E4U1K6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

709032:SULKU RS01055
gene id: 709032:SULKU_RS01055
uniprot id: E4TXV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

709032:SULKU RS10465
gene id: 709032:SULKU_RS10465
uniprot id: E4U2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

709032:SULKU RS11415
gene id: 709032:SULKU_RS11415
uniprot id: E4TX64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

709032:SULKU RS02790
gene id: 709032:SULKU_RS02790
uniprot id: E4U0B9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

709032:SULKU RS03235
gene id: 709032:SULKU_RS03235
uniprot id: E4U0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

709032:SULKU RS12835
gene id: 709032:SULKU_RS12835
uniprot id: E4TZH5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

709032:SULKU RS01945
gene id: 709032:SULKU_RS01945
uniprot id: E4TZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

709032:SULKU RS07995
gene id: 709032:SULKU_RS07995
uniprot id: E4U062
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS00730
gene id: 709032:SULKU_RS00730
uniprot id: E4TXB0
names: Similarity
messages: Belongs to the UPF0047 family.

709032:SULKU RS05860
gene id: 709032:SULKU_RS05860
uniprot id: E4TWY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS11180
gene id: 709032:SULKU_RS11180
uniprot id: E4TWN6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

709032:SULKU RS10950
gene id: 709032:SULKU_RS10950
uniprot id: E4U3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS00565
gene id: 709032:SULKU_RS00565
uniprot id: E4TWU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS03290
gene id: 709032:SULKU_RS03290
uniprot id: E4U0U2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

709032:SULKU RS07655
gene id: 709032:SULKU_RS07655
uniprot id: E4TZS5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

709032:SULKU RS01135
gene id: 709032:SULKU_RS01135
uniprot id: E4TXX5
names: Similarity
messages: Belongs to the thioredoxin family.

709032:SULKU RS01705
gene id: 709032:SULKU_RS01705
uniprot id: E4TZ03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS08035
gene id: 709032:SULKU_RS08035
uniprot id: E4U071
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS00580
gene id: 709032:SULKU_RS00580
uniprot id: E4TWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

709032:SULKU RS01495
gene id: 709032:SULKU_RS01495
uniprot id: E4TYI2
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

709032:SULKU RS04860
gene id: 709032:SULKU_RS04860
uniprot id: E4U2N9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

709032:SULKU RS00035
gene id: 709032:SULKU_RS00035
uniprot id: E4TW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS13260
gene id: 709032:SULKU_RS13260
uniprot id: E4U3L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

709032:SULKU RS01845
gene id: 709032:SULKU_RS01845
uniprot id: E4TZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

709032:SULKU RS11565
gene id: 709032:SULKU_RS11565
uniprot id: E4TX90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

709032:SULKU RS02525
gene id: 709032:SULKU_RS02525
uniprot id: E4TZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

709032:SULKU RS09765
gene id: 709032:SULKU_RS09765
uniprot id: E4U243
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

709032:SULKU RS10680
gene id: 709032:SULKU_RS10680
uniprot id: E4U384
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

709032:SULKU RS00905
gene id: 709032:SULKU_RS00905
uniprot id: E4TXE5
names: Similarity
messages: Belongs to the bacterial secretin family.

709032:SULKU RS08755
gene id: 709032:SULKU_RS08755
uniprot id: E4U103
names: Similarity
messages: Belongs to the SCO1/2 family.

709032:SULKU RS09030
gene id: 709032:SULKU_RS09030
uniprot id: E4U1C3
names: Similarity
messages: Belongs to the YciI family.

709032:SULKU RS06230
gene id: 709032:SULKU_RS06230
uniprot id: E4TXI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS09705
gene id: 709032:SULKU_RS09705
uniprot id: E4U238
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

709032:SULKU RS13440
gene id: 709032:SULKU_RS13440
uniprot id: E4U3Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS02465
gene id: 709032:SULKU_RS02465
uniprot id: E4TZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

709032:SULKU RS03480
gene id: 709032:SULKU_RS03480
uniprot id: E4U147
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

709032:SULKU RS13175
gene id: 709032:SULKU_RS13175
uniprot id: E4U3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

709032:SULKU RS04495
gene id: 709032:SULKU_RS04495
uniprot id: E4U2A2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

709032:SULKU RS04065
gene id: 709032:SULKU_RS04065
uniprot id: E4U1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

709032:SULKU RS04765
gene id: 709032:SULKU_RS04765
uniprot id: E4U2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

709032:SULKU RS03850
gene id: 709032:SULKU_RS03850
uniprot id: E4U1J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

709032:SULKU RS00980
gene id: 709032:SULKU_RS00980
uniprot id: E4TXG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

709032:SULKU RS09055
gene id: 709032:SULKU_RS09055
uniprot id: E4U1C8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

709032:SULKU RS12705
gene id: 709032:SULKU_RS12705
uniprot id: E4TZE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

709032:SULKU RS04280
gene id: 709032:SULKU_RS04280
uniprot id: E4U1Y9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS11015
gene id: 709032:SULKU_RS11015
uniprot id: E4TWK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS09290
gene id: 709032:SULKU_RS09290
uniprot id: E4U1N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS03815
gene id: 709032:SULKU_RS03815
uniprot id: E4U1I3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

709032:SULKU RS00300
gene id: 709032:SULKU_RS00300
uniprot id: E4TWB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

709032:SULKU RS08075
gene id: 709032:SULKU_RS08075
uniprot id: E4U080
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

709032:SULKU RS10705
gene id: 709032:SULKU_RS10705
uniprot id: E4U389
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

709032:SULKU RS11105
gene id: 709032:SULKU_RS11105
uniprot id: E4TWM2
names: Similarity
messages: Belongs to the peptidase S11 family.

709032:SULKU RS01580
gene id: 709032:SULKU_RS01580
uniprot id: E4TYJ9
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS14015
gene id: 709032:SULKU_RS14015
uniprot id: E4U421
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

709032:SULKU RS04415
gene id: 709032:SULKU_RS04415
uniprot id: E4U286
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS00045
gene id: 709032:SULKU_RS00045
uniprot id: E4TW61
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

709032:SULKU RS05700
gene id: 709032:SULKU_RS05700
uniprot id: E4TWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

709032:SULKU RS05935
gene id: 709032:SULKU_RS05935
uniprot id: E4TX00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

709032:SULKU RS11435
gene id: 709032:SULKU_RS11435
uniprot id: E4TX68
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

709032:SULKU RS09405
gene id: 709032:SULKU_RS09405
uniprot id: E4U1R2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

709032:SULKU RS08780
gene id: 709032:SULKU_RS08780
uniprot id: E4U108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

709032:SULKU RS03800
gene id: 709032:SULKU_RS03800
uniprot id: E4U1I0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

709032:SULKU RS06815
gene id: 709032:SULKU_RS06815
uniprot id: E4TYM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

709032:SULKU RS01565
gene id: 709032:SULKU_RS01565
uniprot id: E4TYJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

709032:SULKU RS10290
gene id: 709032:SULKU_RS10290
uniprot id: E4U2U3
names: Similarity
messages: Belongs to the peptidase A31 family.

709032:SULKU RS08700
gene id: 709032:SULKU_RS08700
uniprot id: E4U0Z2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

709032:SULKU RS02130
gene id: 709032:SULKU_RS02130
uniprot id: E4TZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

709032:SULKU RS10060
gene id: 709032:SULKU_RS10060
uniprot id: E4U2H1
names: Similarity
messages: Belongs to the polypeptide deformylase family.

709032:SULKU RS13915
gene id: 709032:SULKU_RS13915
uniprot id: E4U400
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

709032:SULKU RS06430
gene id: 709032:SULKU_RS06430
uniprot id: E4TXM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS09245
gene id: 709032:SULKU_RS09245
uniprot id: E4U1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

709032:SULKU RS12440
gene id: 709032:SULKU_RS12440
uniprot id: E4TYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

709032:SULKU RS11550
gene id: 709032:SULKU_RS11550
uniprot id: E4TX87
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

709032:SULKU RS01775
gene id: 709032:SULKU_RS01775
uniprot id: E4TZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

709032:SULKU RS04990
gene id: 709032:SULKU_RS04990
uniprot id: E4U2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

709032:SULKU RS03330
gene id: 709032:SULKU_RS03330
uniprot id: E4U0V0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

709032:SULKU RS01910
gene id: 709032:SULKU_RS01910
uniprot id: E4TZ41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

709032:SULKU RS07225
gene id: 709032:SULKU_RS07225
uniprot id: E4TZ82
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

709032:SULKU RS04815
gene id: 709032:SULKU_RS04815
uniprot id: E4U2N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709032:SULKU RS05060
gene id: 709032:SULKU_RS05060
uniprot id: E4U2S9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

709032:SULKU RS03415
gene id: 709032:SULKU_RS03415
uniprot id: E4U134
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

709032:SULKU RS00710
gene id: 709032:SULKU_RS00710
uniprot id: E4TXA6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

709032:SULKU RS10985
gene id: 709032:SULKU_RS10985
uniprot id: E4TWJ7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

709032:SULKU RS04075
gene id: 709032:SULKU_RS04075
uniprot id: E4U1U8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

709032:SULKU RS00190
gene id: 709032:SULKU_RS00190
uniprot id: E4TW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

709032:SULKU RS10880
gene id: 709032:SULKU_RS10880
uniprot id: E4U3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

709032:SULKU RS05790
gene id: 709032:SULKU_RS05790
uniprot id: E4TWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

709032:SULKU RS00785
gene id: 709032:SULKU_RS00785
uniprot id: E4TXC1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

709032:SULKU RS00090
gene id: 709032:SULKU_RS00090
uniprot id: E4TW70
names: Subcellular Location Annotation
messages: Membrane

709032:SULKU RS11040
gene id: 709032:SULKU_RS11040
uniprot id: E4TWK9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

709032:SULKU RS01365
gene id: 709032:SULKU_RS01365
uniprot id: E4TY21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.