698758:AXY RS00370
gene id: 698758:AXY_RS00370
uniprot id: K0J155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

698758:AXY RS10545
gene id: 698758:AXY_RS10545
uniprot id: K0J5I1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

698758:AXY RS06385
gene id: 698758:AXY_RS06385
uniprot id: K0IXZ4
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

698758:AXY RS07690
gene id: 698758:AXY_RS07690
uniprot id: K0J3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

698758:AXY RS12085
gene id: 698758:AXY_RS12085
uniprot id: K0J543
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

698758:AXY RS05390
gene id: 698758:AXY_RS05390
uniprot id: K0IXJ2
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07440
gene id: 698758:AXY_RS07440
uniprot id: K0J388
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

698758:AXY RS05660
gene id: 698758:AXY_RS05660
uniprot id: K0J3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

698758:AXY RS05030
gene id: 698758:AXY_RS05030
uniprot id: K0IXH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

698758:AXY RS10420
gene id: 698758:AXY_RS10420
uniprot id: K0J5G8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

698758:AXY RS07895
gene id: 698758:AXY_RS07895
uniprot id: K0J3H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

698758:AXY RS00825
gene id: 698758:AXY_RS00825
uniprot id: K0IZ76
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

698758:AXY RS10865
gene id: 698758:AXY_RS10865
uniprot id: K0J0B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

698758:AXY RS08410
gene id: 698758:AXY_RS08410
uniprot id: K0J4S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS10430
gene id: 698758:AXY_RS10430
uniprot id: K0J7Y8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS09225
gene id: 698758:AXY_RS09225
uniprot id: K0IZL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS05265
gene id: 698758:AXY_RS05265
uniprot id: K0IXI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

698758:AXY RS07480
gene id: 698758:AXY_RS07480
uniprot id: K0IYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

698758:AXY RS00705
gene id: 698758:AXY_RS00705
uniprot id: K0J5P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

698758:AXY RS10250
gene id: 698758:AXY_RS10250
uniprot id: K0J7Y1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

698758:AXY RS09850
gene id: 698758:AXY_RS09850
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS10375
gene id: 698758:AXY_RS10375
uniprot id: K0J4H8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

698758:AXY RS01510
gene id: 698758:AXY_RS01510
uniprot id: K0J1Q6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

698758:AXY RS11120
gene id: 698758:AXY_RS11120
uniprot id: K0J5P4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

698758:AXY RS09105
gene id: 698758:AXY_RS09105
uniprot id: K0IZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS00270
gene id: 698758:AXY_RS00270
uniprot id: K0J143
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

698758:AXY RS06735
gene id: 698758:AXY_RS06735
uniprot id: K0J7I4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

698758:AXY RS10450
gene id: 698758:AXY_RS10450
uniprot id: K0J4I2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

698758:AXY RS01595
gene id: 698758:AXY_RS01595
uniprot id: K0J5Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS08985
gene id: 698758:AXY_RS08985
uniprot id: K0IZC3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

698758:AXY RS03005
gene id: 698758:AXY_RS03005
uniprot id: K0J2H5
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08255
gene id: 698758:AXY_RS08255
uniprot id: K0IYX9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

698758:AXY RS00085
gene id: 698758:AXY_RS00085
uniprot id: K0J5I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

698758:AXY RS09365
gene id: 698758:AXY_RS09365
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS06590
gene id: 698758:AXY_RS06590
uniprot id: K0J7H5
names: Similarity
messages: Belongs to the peptidase C40 family.

698758:AXY RS07675
gene id: 698758:AXY_RS07675
uniprot id: K0IYW3
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS05555
gene id: 698758:AXY_RS05555
uniprot id: K0IXT2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

698758:AXY RS00570
gene id: 698758:AXY_RS00570
uniprot id: K0IV69
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

698758:AXY RS01990
gene id: 698758:AXY_RS01990
uniprot id: K0IVN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

698758:AXY RS02795
gene id: 698758:AXY_RS02795
uniprot id: K0J0J4
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

698758:AXY RS03075
gene id: 698758:AXY_RS03075
uniprot id: K0IW87
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS02080
gene id: 698758:AXY_RS02080
uniprot id: K0J651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05010
gene id: 698758:AXY_RS05010
uniprot id: K0IXB3
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08215
gene id: 698758:AXY_RS08215
uniprot id: K0J3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

698758:AXY RS05775
gene id: 698758:AXY_RS05775
uniprot id: K0IXW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

698758:AXY RS03855
gene id: 698758:AXY_RS03855
uniprot id: K0J2S9
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS02415
gene id: 698758:AXY_RS02415
uniprot id: K0IVX2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

698758:AXY RS00060
gene id: 698758:AXY_RS00060
uniprot id: K0IUX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09580
gene id: 698758:AXY_RS09580
uniprot id: K0IZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

698758:AXY RS10885
gene id: 698758:AXY_RS10885
uniprot id: K0J0F0
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

698758:AXY RS08055
gene id: 698758:AXY_RS08055
uniprot id: K0IYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

698758:AXY RS10620
gene id: 698758:AXY_RS10620
uniprot id: K0J5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

698758:AXY RS02815
gene id: 698758:AXY_RS02815
uniprot id: K0J2F1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

698758:AXY RS00055
gene id: 698758:AXY_RS00055
uniprot id: K0J5I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

698758:AXY RS09680
gene id: 698758:AXY_RS09680
uniprot id: K0IZQ6
names: Similarity
messages: Belongs to the IMPACT family.

698758:AXY RS11775
gene id: 698758:AXY_RS11775
uniprot id: K0J505
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

698758:AXY RS07515
gene id: 698758:AXY_RS07515
uniprot id: K0J3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

698758:AXY RS00635
gene id: 698758:AXY_RS00635
uniprot id: K0IV16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

698758:AXY RS12040
gene id: 698758:AXY_RS12040
uniprot id: K0J855
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

698758:AXY RS01505
gene id: 698758:AXY_RS01505
uniprot id: K0IVG4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

698758:AXY RS06755
gene id: 698758:AXY_RS06755
uniprot id: K0J2T3
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

698758:AXY RS00365
gene id: 698758:AXY_RS00365
uniprot id: K0IV60
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS04295
gene id: 698758:AXY_RS04295
uniprot id: K0J2Z1
names: Similarity
messages: Belongs to the HsdR family.

698758:AXY RS01820
gene id: 698758:AXY_RS01820
uniprot id: K0IVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

698758:AXY RS08700
gene id: 698758:AXY_RS08700
uniprot id: K0J3U4
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

698758:AXY RS00460
gene id: 698758:AXY_RS00460
uniprot id: K0J5M4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS04845
gene id: 698758:AXY_RS04845
uniprot id: K0J1S6
names: Similarity
messages: Belongs to the citrate synthase family.

698758:AXY RS02310
gene id: 698758:AXY_RS02310
uniprot id: K0IW06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

698758:AXY RS07970
gene id: 698758:AXY_RS07970
uniprot id: K0J7N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

698758:AXY RS06830
gene id: 698758:AXY_RS06830
uniprot id: K0J2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

698758:AXY RS06950
gene id: 698758:AXY_RS06950
uniprot id: K0J4A5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

698758:AXY RS00180
gene id: 698758:AXY_RS00180
uniprot id: K0IYV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

698758:AXY RS11615
gene id: 698758:AXY_RS11615
uniprot id: K0J837
names: Similarity
messages: Belongs to the peptidase S24 family.

698758:AXY RS08100
gene id: 698758:AXY_RS08100
uniprot id: K0IZ31
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS10880
gene id: 698758:AXY_RS10880
uniprot id: K0J806
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

698758:AXY RS06425
gene id: 698758:AXY_RS06425
uniprot id: K0J7G2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

698758:AXY RS08250
gene id: 698758:AXY_RS08250
uniprot id: K0IZ49
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

698758:AXY RS05075
gene id: 698758:AXY_RS05075
uniprot id: K0J767
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

698758:AXY RS00875
gene id: 698758:AXY_RS00875
uniprot id: K0J5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

698758:AXY RS05195
gene id: 698758:AXY_RS05195
uniprot id: K0IXH0
names: Similarity
messages: Belongs to the GSP E family.

698758:AXY RS07005
gene id: 698758:AXY_RS07005
uniprot id: K0J2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

698758:AXY RS06870
gene id: 698758:AXY_RS06870
uniprot id: K0IY87
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

698758:AXY RS01240
gene id: 698758:AXY_RS01240
uniprot id: K0IZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

698758:AXY RS11400
gene id: 698758:AXY_RS11400
uniprot id: K0J0J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

698758:AXY RS08920
gene id: 698758:AXY_RS08920
uniprot id: K0J4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

698758:AXY RS09600
gene id: 698758:AXY_RS09600
uniprot id: K0IZS3
names: Similarity
messages: Belongs to the bacterial flagellin family.

698758:AXY RS06440
gene id: 698758:AXY_RS06440
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS02635
gene id: 698758:AXY_RS02635
uniprot id: K0IWD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

698758:AXY RS01755
gene id: 698758:AXY_RS01755
uniprot id: K0IVL7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS07995
gene id: 698758:AXY_RS07995
uniprot id: K0J7N9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

698758:AXY RS00790
gene id: 698758:AXY_RS00790
uniprot id: K0IV91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

698758:AXY RS04610
gene id: 698758:AXY_RS04610
uniprot id: K0J348
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

698758:AXY RS07455
gene id: 698758:AXY_RS07455
uniprot id: K0IYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

698758:AXY RS02725
gene id: 698758:AXY_RS02725
uniprot id: K0J6H2
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS08395
gene id: 698758:AXY_RS08395
uniprot id: K0J7Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

698758:AXY RS11090
gene id: 698758:AXY_RS11090
uniprot id: K0J0E1
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS11875
gene id: 698758:AXY_RS11875
uniprot id: K0J0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

698758:AXY RS06125
gene id: 698758:AXY_RS06125
uniprot id: K0J7D9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

698758:AXY RS09645
gene id: 698758:AXY_RS09645
uniprot id: K0J7V6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

698758:AXY RS03305
gene id: 698758:AXY_RS03305
uniprot id: K0IWC0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

698758:AXY RS07395
gene id: 698758:AXY_RS07395
uniprot id: K0J7L5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

698758:AXY RS00010
gene id: 698758:AXY_RS00010
uniprot id: K0IUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

698758:AXY RS06250
gene id: 698758:AXY_RS06250
uniprot id: K0J7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

698758:AXY RS06120
gene id: 698758:AXY_RS06120
uniprot id: K0J2D0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

698758:AXY RS03900
gene id: 698758:AXY_RS03900
uniprot id: K0J2T6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS10305
gene id: 698758:AXY_RS10305
uniprot id: K0J7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

698758:AXY RS09325
gene id: 698758:AXY_RS09325
uniprot id: K0IZN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

698758:AXY RS07720
gene id: 698758:AXY_RS07720
uniprot id: K0J7M8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

698758:AXY RS07135
gene id: 698758:AXY_RS07135
uniprot id: K0J7K4
names: Function
messages: Involved in the transposition of the insertion sequence.

698758:AXY RS01635
gene id: 698758:AXY_RS01635
uniprot id: K0J1T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

698758:AXY RS09040
gene id: 698758:AXY_RS09040
uniprot id: K0IZD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS02810
gene id: 698758:AXY_RS02810
uniprot id: K0IW50
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

698758:AXY RS08650
gene id: 698758:AXY_RS08650
uniprot id: K0J4V1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

698758:AXY RS05680
gene id: 698758:AXY_RS05680
uniprot id: K0IXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

698758:AXY RS04440
gene id: 698758:AXY_RS04440
uniprot id: K0IX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

698758:AXY RS06945
gene id: 698758:AXY_RS06945
uniprot id: K0IYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

698758:AXY RS00035
gene id: 698758:AXY_RS00035
uniprot id: K0IUW9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

698758:AXY RS06170
gene id: 698758:AXY_RS06170
uniprot id: K0J7E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

698758:AXY RS03700
gene id: 698758:AXY_RS03700
uniprot id: K0J2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

698758:AXY RS06270
gene id: 698758:AXY_RS06270
uniprot id: K0J2H2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

698758:AXY RS08390
gene id: 698758:AXY_RS08390
uniprot id: K0J3P5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

698758:AXY RS00740
gene id: 698758:AXY_RS00740
uniprot id: K0IV86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

698758:AXY RS12260
gene id: 698758:AXY_RS12260
uniprot id: K0J206
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

698758:AXY RS04060
gene id: 698758:AXY_RS04060
uniprot id: K0J6V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

698758:AXY RS01690
gene id: 698758:AXY_RS01690
uniprot id: K0IZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

698758:AXY RS06680
gene id: 698758:AXY_RS06680
uniprot id: K0J468
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS00855
gene id: 698758:AXY_RS00855
uniprot id: K0J5R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

698758:AXY RS10160
gene id: 698758:AXY_RS10160
uniprot id: K0J5E9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

698758:AXY RS05910
gene id: 698758:AXY_RS05910
uniprot id: K0IXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03740
gene id: 698758:AXY_RS03740
uniprot id: K0IWT1
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS05670
gene id: 698758:AXY_RS05670
uniprot id: K0J7A9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

698758:AXY RS03210
gene id: 698758:AXY_RS03210
uniprot id: K0J0T2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

698758:AXY RS11085
gene id: 698758:AXY_RS11085
uniprot id: K0J0J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

698758:AXY RS07390
gene id: 698758:AXY_RS07390
uniprot id: K0J375
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

698758:AXY RS11195
gene id: 698758:AXY_RS11195
uniprot id: K0J4S0
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

698758:AXY RS01160
gene id: 698758:AXY_RS01160
uniprot id: K0IV92
names: Similarity
messages: Belongs to the peptidase S14 family.

698758:AXY RS02695
gene id: 698758:AXY_RS02695
uniprot id: K0J0H1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

698758:AXY RS00805
gene id: 698758:AXY_RS00805
uniprot id: K0J5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

698758:AXY RS04990
gene id: 698758:AXY_RS04990
uniprot id: K0J3E3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

698758:AXY RS02870
gene id: 698758:AXY_RS02870
uniprot id: K0J0L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

698758:AXY RS06815
gene id: 698758:AXY_RS06815
uniprot id: K0IYD8
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

698758:AXY RS05000
gene id: 698758:AXY_RS05000
uniprot id: K0J753
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

698758:AXY RS00830
gene id: 698758:AXY_RS00830
uniprot id: K0J5R0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

698758:AXY RS06150
gene id: 698758:AXY_RS06150
uniprot id: K0IY24
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

698758:AXY RS07510
gene id: 698758:AXY_RS07510
uniprot id: K0J4H1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS07290
gene id: 698758:AXY_RS07290
uniprot id: K0J4E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

698758:AXY RS04995
gene id: 698758:AXY_RS04995
uniprot id: K0J1V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

698758:AXY RS03715
gene id: 698758:AXY_RS03715
uniprot id: K0IWS6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS08665
gene id: 698758:AXY_RS08665
uniprot id: K0IZB9
names: Similarity
messages: Belongs to the Dps family.

698758:AXY RS05755
gene id: 698758:AXY_RS05755
uniprot id: K0IXN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

698758:AXY RS08800
gene id: 698758:AXY_RS08800
uniprot id: K0J3V8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

698758:AXY RS10380
gene id: 698758:AXY_RS10380
uniprot id: K0J7Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS05655
gene id: 698758:AXY_RS05655
uniprot id: K0IXM5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

698758:AXY RS07940
gene id: 698758:AXY_RS07940
uniprot id: K0J4M0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

698758:AXY RS10740
gene id: 698758:AXY_RS10740
uniprot id: K0J091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

698758:AXY RS06435
gene id: 698758:AXY_RS06435
uniprot id: K0IY02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

698758:AXY RS08540
gene id: 698758:AXY_RS08540
uniprot id: K0J7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

698758:AXY RS11880
gene id: 698758:AXY_RS11880
uniprot id: K0J5Y0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

698758:AXY RS06725
gene id: 698758:AXY_RS06725
uniprot id: K0J475
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

698758:AXY RS04625
gene id: 698758:AXY_RS04625
uniprot id: K0IXA3
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS02200
gene id: 698758:AXY_RS02200
uniprot id: K0J009
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

698758:AXY RS02220
gene id: 698758:AXY_RS02220
uniprot id: K0J239
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08995
gene id: 698758:AXY_RS08995
uniprot id: K0J4Y8
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS10265
gene id: 698758:AXY_RS10265
uniprot id: K0J5F6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

698758:AXY RS06475
gene id: 698758:AXY_RS06475
uniprot id: K0IY77
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

698758:AXY RS08020
gene id: 698758:AXY_RS08020
uniprot id: K0J7P0
names: Similarity
messages: Belongs to the YggT family.

698758:AXY RS08580
gene id: 698758:AXY_RS08580
uniprot id: K0J4U3
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS09490
gene id: 698758:AXY_RS09490
uniprot id: K0IZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

698758:AXY RS05745
gene id: 698758:AXY_RS05745
uniprot id: K0J7B5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

698758:AXY RS08795
gene id: 698758:AXY_RS08795
uniprot id: K0J4W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

698758:AXY RS03555
gene id: 698758:AXY_RS03555
uniprot id: K0J0X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS04180
gene id: 698758:AXY_RS04180
uniprot id: K0J1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03525
gene id: 698758:AXY_RS03525
uniprot id: K0IWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

698758:AXY RS12070
gene id: 698758:AXY_RS12070
uniprot id: K0J187
names: Similarity
messages: Belongs to the ParB family.

698758:AXY RS08435
gene id: 698758:AXY_RS08435
uniprot id: K0J4S5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

698758:AXY RS11675
gene id: 698758:AXY_RS11675
uniprot id: K0J4Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

698758:AXY RS11515
gene id: 698758:AXY_RS11515
uniprot id: K0J833
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

698758:AXY RS01070
gene id: 698758:AXY_RS01070
uniprot id: K0J1F5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

698758:AXY RS00780
gene id: 698758:AXY_RS00780
uniprot id: K0J5Q3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS07790
gene id: 698758:AXY_RS07790
uniprot id: K0J3G2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

698758:AXY RS09795
gene id: 698758:AXY_RS09795
uniprot id: K0IZS5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

698758:AXY RS07400
gene id: 698758:AXY_RS07400
uniprot id: K0IYN7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS10770
gene id: 698758:AXY_RS10770
uniprot id: K0J5K6
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

698758:AXY RS09230
gene id: 698758:AXY_RS09230
uniprot id: K0IZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

698758:AXY RS11305
gene id: 698758:AXY_RS11305
uniprot id: K0J0H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

698758:AXY RS05760
gene id: 698758:AXY_RS05760
uniprot id: K0J3T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

698758:AXY RS01435
gene id: 698758:AXY_RS01435
uniprot id: K0J1P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

698758:AXY RS06915
gene id: 698758:AXY_RS06915
uniprot id: K0IYF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

698758:AXY RS09160
gene id: 698758:AXY_RS09160
uniprot id: K0J507
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

698758:AXY RS08865
gene id: 698758:AXY_RS08865
uniprot id: K0IZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

698758:AXY RS09125
gene id: 698758:AXY_RS09125
uniprot id: K0J7T5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS03470
gene id: 698758:AXY_RS03470
uniprot id: K0J6N8
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS03085
gene id: 698758:AXY_RS03085
uniprot id: K0J0Q8
names: Similarity
messages: Belongs to the UPF0237 family.

698758:AXY RS08120
gene id: 698758:AXY_RS08120
uniprot id: K0J7P4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS03705
gene id: 698758:AXY_RS03705
uniprot id: K0J101
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

698758:AXY RS00100
gene id: 698758:AXY_RS00100
uniprot id: K0J119
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

698758:AXY RS10165
gene id: 698758:AXY_RS10165
uniprot id: K0J4G6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

698758:AXY RS05510
gene id: 698758:AXY_RS05510
uniprot id: K0IXK6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

698758:AXY RS06885
gene id: 698758:AXY_RS06885
uniprot id: K0J7J4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

698758:AXY RS05165
gene id: 698758:AXY_RS05165
uniprot id: K0IXM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

698758:AXY RS05425
gene id: 698758:AXY_RS05425
uniprot id: K0J238
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS01895
gene id: 698758:AXY_RS01895
uniprot id: K0IVL4
names: Similarity
messages: Belongs to the carbamate kinase family.

698758:AXY RS08145
gene id: 698758:AXY_RS08145
uniprot id: K0J7P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

698758:AXY RS02275
gene id: 698758:AXY_RS02275
uniprot id: K0J027
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

698758:AXY RS05625
gene id: 698758:AXY_RS05625
uniprot id: K0IXU5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

698758:AXY RS00760
gene id: 698758:AXY_RS00760
uniprot id: K0IV32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

698758:AXY RS10670
gene id: 698758:AXY_RS10670
uniprot id: K0J5J4
names: Similarity
messages: Belongs to the TrpC family.

698758:AXY RS10290
gene id: 698758:AXY_RS10290
uniprot id: K0J5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

698758:AXY RS06505
gene id: 698758:AXY_RS06505
uniprot id: K0IY17
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

698758:AXY RS06380
gene id: 698758:AXY_RS06380
uniprot id: K0IY61
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

698758:AXY RS01640
gene id: 698758:AXY_RS01640
uniprot id: K0IZP6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

698758:AXY RS08535
gene id: 698758:AXY_RS08535
uniprot id: K0J3R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

698758:AXY RS05020
gene id: 698758:AXY_RS05020
uniprot id: K0J1W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

698758:AXY RS01655
gene id: 698758:AXY_RS01655
uniprot id: K0IVJ9
names: Similarity
messages: Belongs to the ThiD family.

698758:AXY RS07820
gene id: 698758:AXY_RS07820
uniprot id: K0J7N2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

698758:AXY RS08385
gene id: 698758:AXY_RS08385
uniprot id: K0J4R8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

698758:AXY RS03460
gene id: 698758:AXY_RS03460
uniprot id: K0J2L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

698758:AXY RS04930
gene id: 698758:AXY_RS04930
uniprot id: K0IXF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

698758:AXY RS10600
gene id: 698758:AXY_RS10600
uniprot id: K0J4J6
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS09140
gene id: 698758:AXY_RS09140
uniprot id: K0J504
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS00565
gene id: 698758:AXY_RS00565
uniprot id: K0IV08
names: Similarity
messages: Belongs to the ClpA/ClpB family.

698758:AXY RS04705
gene id: 698758:AXY_RS04705
uniprot id: K0IX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS00420
gene id: 698758:AXY_RS00420
uniprot id: K0IV64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS07965
gene id: 698758:AXY_RS07965
uniprot id: K0J3I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

698758:AXY RS04170
gene id: 698758:AXY_RS04170
uniprot id: K0IWR0
names: Similarity
messages: Belongs to the universal stress protein A family.

698758:AXY RS01845
gene id: 698758:AXY_RS01845
uniprot id: K0IVJ7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

698758:AXY RS08130
gene id: 698758:AXY_RS08130
uniprot id: K0IYV8
names: Similarity
messages: Belongs to the transpeptidase family.

698758:AXY RS06230
gene id: 698758:AXY_RS06230
uniprot id: K0IY35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

698758:AXY RS05140
gene id: 698758:AXY_RS05140
uniprot id: K0IXM3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

698758:AXY RS09075
gene id: 698758:AXY_RS09075
uniprot id: K0J7T3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS06490
gene id: 698758:AXY_RS06490
uniprot id: K0J2M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

698758:AXY RS06875
gene id: 698758:AXY_RS06875
uniprot id: K0J498
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

698758:AXY RS05980
gene id: 698758:AXY_RS05980
uniprot id: K0IXZ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

698758:AXY RS03035
gene id: 698758:AXY_RS03035
uniprot id: K0J0P9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS05210
gene id: 698758:AXY_RS05210
uniprot id: K0J776
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

698758:AXY RS08275
gene id: 698758:AXY_RS08275
uniprot id: K0IZ53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

698758:AXY RS09035
gene id: 698758:AXY_RS09035
uniprot id: K0IZI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

698758:AXY RS07840
gene id: 698758:AXY_RS07840
uniprot id: K0J3G7
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

698758:AXY RS03485
gene id: 698758:AXY_RS03485
uniprot id: K0J2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

698758:AXY RS04410
gene id: 698758:AXY_RS04410
uniprot id: K0J6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

698758:AXY RS06285
gene id: 698758:AXY_RS06285
uniprot id: K0IXX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

698758:AXY RS00195
gene id: 698758:AXY_RS00195
uniprot id: K0IV45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

698758:AXY RS00860
gene id: 698758:AXY_RS00860
uniprot id: K0IV47
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

698758:AXY RS05740
gene id: 698758:AXY_RS05740
uniprot id: K0J276
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

698758:AXY RS01605
gene id: 698758:AXY_RS01605
uniprot id: K0IVI5
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07055
gene id: 698758:AXY_RS07055
uniprot id: K0J2Y9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

698758:AXY RS11360
gene id: 698758:AXY_RS11360
uniprot id: K0J4U2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

698758:AXY RS00845
gene id: 698758:AXY_RS00845
uniprot id: K0J1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

698758:AXY RS09310
gene id: 698758:AXY_RS09310
uniprot id: K0J525
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

698758:AXY RS03120
gene id: 698758:AXY_RS03120
uniprot id: K0IWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

698758:AXY RS02005
gene id: 698758:AXY_RS02005
uniprot id: K0IZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

698758:AXY RS04220
gene id: 698758:AXY_RS04220
uniprot id: K0IWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS07655
gene id: 698758:AXY_RS07655
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS05435
gene id: 698758:AXY_RS05435
uniprot id: K0IXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

698758:AXY RS07600
gene id: 698758:AXY_RS07600
uniprot id: K0IYU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

698758:AXY RS08030
gene id: 698758:AXY_RS08030
uniprot id: K0IYU3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

698758:AXY RS05255
gene id: 698758:AXY_RS05255
uniprot id: K0J779
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

698758:AXY RS01975
gene id: 698758:AXY_RS01975
uniprot id: K0J1Z4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

698758:AXY RS03310
gene id: 698758:AXY_RS03310
uniprot id: K0J2K6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

698758:AXY RS01490
gene id: 698758:AXY_RS01490
uniprot id: K0IZL3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

698758:AXY RS00665
gene id: 698758:AXY_RS00665
uniprot id: K0IV79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

698758:AXY RS06005
gene id: 698758:AXY_RS06005
uniprot id: K0IXZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

698758:AXY RS00375
gene id: 698758:AXY_RS00375
uniprot id: K0IZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

698758:AXY RS11780
gene id: 698758:AXY_RS11780
uniprot id: K0J844
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

698758:AXY RS04425
gene id: 698758:AXY_RS04425
uniprot id: K0J312
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06160
gene id: 698758:AXY_RS06160
uniprot id: K0J3Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

698758:AXY RS06895
gene id: 698758:AXY_RS06895
uniprot id: K0IY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

698758:AXY RS11890
gene id: 698758:AXY_RS11890
uniprot id: K0J849
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

698758:AXY RS05545
gene id: 698758:AXY_RS05545
uniprot id: K0J252
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

698758:AXY RS02510
gene id: 698758:AXY_RS02510
uniprot id: K0IVZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

698758:AXY RS06065
gene id: 698758:AXY_RS06065
uniprot id: K0J3X7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

698758:AXY RS00075
gene id: 698758:AXY_RS00075
uniprot id: K0J117
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

698758:AXY RS11695
gene id: 698758:AXY_RS11695
uniprot id: K0J5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS06175
gene id: 698758:AXY_RS06175
uniprot id: K0IY27
names: Similarity
messages: Belongs to the Nudix hydrolase family.

698758:AXY RS06395
gene id: 698758:AXY_RS06395
uniprot id: K0J2K3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

698758:AXY RS07760
gene id: 698758:AXY_RS07760
uniprot id: K0J4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03560
gene id: 698758:AXY_RS03560
uniprot id: K0J6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

698758:AXY RS03575
gene id: 698758:AXY_RS03575
uniprot id: K0J2N1
names: Similarity
messages: Belongs to the peptidase S41A family.

698758:AXY RS04260
gene id: 698758:AXY_RS04260
uniprot id: K0J6X4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

698758:AXY RS10785
gene id: 698758:AXY_RS10785
uniprot id: K0J0C5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

698758:AXY RS07795
gene id: 698758:AXY_RS07795
uniprot id: K0J7N1
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

698758:AXY RS10215
gene id: 698758:AXY_RS10215
uniprot id: K0J5F2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

698758:AXY RS04945
gene id: 698758:AXY_RS04945
uniprot id: K0J1U9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

698758:AXY RS11885
gene id: 698758:AXY_RS11885
uniprot id: K0J522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

698758:AXY RS02285
gene id: 698758:AXY_RS02285
uniprot id: K0IW00
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS10155
gene id: 698758:AXY_RS10155
uniprot id: K0J002
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

698758:AXY RS07750
gene id: 698758:AXY_RS07750
uniprot id: K0IYX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

698758:AXY RS08285
gene id: 698758:AXY_RS08285
uniprot id: K0J4Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

698758:AXY RS03755
gene id: 698758:AXY_RS03755
uniprot id: K0J6S2
names: Similarity
messages: Belongs to the peptidase A8 family.

698758:AXY RS07285
gene id: 698758:AXY_RS07285
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS09605
gene id: 698758:AXY_RS09605
uniprot id: K0IZP0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

698758:AXY RS10315
gene id: 698758:AXY_RS10315
uniprot id: K0J024
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

698758:AXY RS08975
gene id: 698758:AXY_RS08975
uniprot id: K0J7S9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

698758:AXY RS06410
gene id: 698758:AXY_RS06410
uniprot id: K0IXZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

698758:AXY RS07990
gene id: 698758:AXY_RS07990
uniprot id: K0J3I7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

698758:AXY RS03815
gene id: 698758:AXY_RS03815
uniprot id: K0J145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

698758:AXY RS04300
gene id: 698758:AXY_RS04300
uniprot id: K0J1F2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

698758:AXY RS00110
gene id: 698758:AXY_RS00110
uniprot id: K0J5I8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

698758:AXY RS10935
gene id: 698758:AXY_RS10935
uniprot id: K0J0H2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

698758:AXY RS07310
gene id: 698758:AXY_RS07310
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS04230
gene id: 698758:AXY_RS04230
uniprot id: K0J1D7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

698758:AXY RS05370
gene id: 698758:AXY_RS05370
uniprot id: K0J3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

698758:AXY RS11565
gene id: 698758:AXY_RS11565
uniprot id: K0J835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

698758:AXY RS00405
gene id: 698758:AXY_RS00405
uniprot id: K0IZ07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

698758:AXY RS09585
gene id: 698758:AXY_RS09585
uniprot id: K0J561
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

698758:AXY RS10830
gene id: 698758:AXY_RS10830
uniprot id: K0J804
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

698758:AXY RS04460
gene id: 698758:AXY_RS04460
uniprot id: K0J6Z3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

698758:AXY RS10355
gene id: 698758:AXY_RS10355
uniprot id: K0J7Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS01515
gene id: 698758:AXY_RS01515
uniprot id: K0IZL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

698758:AXY RS11735
gene id: 698758:AXY_RS11735
uniprot id: K0J0X3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

698758:AXY RS06810
gene id: 698758:AXY_RS06810
uniprot id: K0J7I8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

698758:AXY RS02615
gene id: 698758:AXY_RS02615
uniprot id: K0IWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

698758:AXY RS06745
gene id: 698758:AXY_RS06745
uniprot id: K0IY64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

698758:AXY RS06825
gene id: 698758:AXY_RS06825
uniprot id: K0J491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

698758:AXY RS03530
gene id: 698758:AXY_RS03530
uniprot id: K0J2M3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

698758:AXY RS04925
gene id: 698758:AXY_RS04925
uniprot id: K0J744
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

698758:AXY RS02835
gene id: 698758:AXY_RS02835
uniprot id: K0IW54
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

698758:AXY RS05215
gene id: 698758:AXY_RS05215
uniprot id: K0IXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

698758:AXY RS02050
gene id: 698758:AXY_RS02050
uniprot id: K0IZY4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

698758:AXY RS00630
gene id: 698758:AXY_RS00630
uniprot id: K0J5N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

698758:AXY RS05240
gene id: 698758:AXY_RS05240
uniprot id: K0IXN4
names: Similarity
messages: Belongs to the UPF0758 family.

698758:AXY RS08735
gene id: 698758:AXY_RS08735
uniprot id: K0IZD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

698758:AXY RS05450
gene id: 698758:AXY_RS05450
uniprot id: K0J240
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS08070
gene id: 698758:AXY_RS08070
uniprot id: K0J7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

698758:AXY RS08075
gene id: 698758:AXY_RS08075
uniprot id: K0IZ27
names: Similarity
messages: Belongs to the UPF0749 family.

698758:AXY RS07855
gene id: 698758:AXY_RS07855
uniprot id: K0IYR8
names: Similarity
messages: Belongs to the asp23 family.

698758:AXY RS05525
gene id: 698758:AXY_RS05525
uniprot id: K0J798
names: Similarity
messages: Belongs to the UPF0473 family.

698758:AXY RS05470
gene id: 698758:AXY_RS05470
uniprot id: K0J3P6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

698758:AXY RS07250
gene id: 698758:AXY_RS07250
uniprot id: K0J7K9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

698758:AXY RS02245
gene id: 698758:AXY_RS02245
uniprot id: K0J244
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

698758:AXY RS00575
gene id: 698758:AXY_RS00575
uniprot id: K0J166
names: Similarity
messages: Belongs to the ycf81 family.

698758:AXY RS04770
gene id: 698758:AXY_RS04770
uniprot id: K0J1Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

698758:AXY RS09110
gene id: 698758:AXY_RS09110
uniprot id: K0IZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS04775
gene id: 698758:AXY_RS04775
uniprot id: K0J725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

698758:AXY RS08140
gene id: 698758:AXY_RS08140
uniprot id: K0J3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

698758:AXY RS07340
gene id: 698758:AXY_RS07340
uniprot id: K0J4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

698758:AXY RS09895
gene id: 698758:AXY_RS09895
uniprot id: K0J4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

698758:AXY RS03565
gene id: 698758:AXY_RS03565
uniprot id: K0IWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

698758:AXY RS04825
gene id: 698758:AXY_RS04825
uniprot id: K0J731
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

698758:AXY RS11055
gene id: 698758:AXY_RS11055
uniprot id: K0J813
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

698758:AXY RS00840
gene id: 698758:AXY_RS00840
uniprot id: K0IV97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

698758:AXY RS05260
gene id: 698758:AXY_RS05260
uniprot id: K0IXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

698758:AXY RS03510
gene id: 698758:AXY_RS03510
uniprot id: K0J0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

698758:AXY RS05905
gene id: 698758:AXY_RS05905
uniprot id: K0IXY2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

698758:AXY RS00620
gene id: 698758:AXY_RS00620
uniprot id: K0J171
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

698758:AXY RS09700
gene id: 698758:AXY_RS09700
uniprot id: K0IZT8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

698758:AXY RS07590
gene id: 698758:AXY_RS07590
uniprot id: K0J3D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

698758:AXY RS04225
gene id: 698758:AXY_RS04225
uniprot id: K0J2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

698758:AXY RS07620
gene id: 698758:AXY_RS07620
uniprot id: K0J7M4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

698758:AXY RS11470
gene id: 698758:AXY_RS11470
uniprot id: K0J831
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

698758:AXY RS07705
gene id: 698758:AXY_RS07705
uniprot id: K0IYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

698758:AXY RS07475
gene id: 698758:AXY_RS07475
uniprot id: K0IYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

698758:AXY RS08930
gene id: 698758:AXY_RS08930
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS07730
gene id: 698758:AXY_RS07730
uniprot id: K0IYQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

698758:AXY RS03150
gene id: 698758:AXY_RS03150
uniprot id: K0IW98
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07545
gene id: 698758:AXY_RS07545
uniprot id: K0J7M1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

698758:AXY RS03515
gene id: 698758:AXY_RS03515
uniprot id: K0J6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

698758:AXY RS09275
gene id: 698758:AXY_RS09275
uniprot id: K0IZM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS06450
gene id: 698758:AXY_RS06450
uniprot id: K0IY73
names: Similarity
messages: Belongs to the UPF0302 family.

698758:AXY RS07710
gene id: 698758:AXY_RS07710
uniprot id: K0J4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

698758:AXY RS04695
gene id: 698758:AXY_RS04695
uniprot id: K0J713
names: Similarity
messages: Belongs to the MotB family.

698758:AXY RS11960
gene id: 698758:AXY_RS11960
uniprot id: K0J529
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS08005
gene id: 698758:AXY_RS08005
uniprot id: K0IYT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

698758:AXY RS06330
gene id: 698758:AXY_RS06330
uniprot id: K0IY54
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

698758:AXY RS04445
gene id: 698758:AXY_RS04445
uniprot id: K0IX20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

698758:AXY RS06840
gene id: 698758:AXY_RS06840
uniprot id: K0IYE4
names: Similarity
messages: Belongs to the CvfB family.

698758:AXY RS06540
gene id: 698758:AXY_RS06540
uniprot id: K0J2N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

698758:AXY RS10170
gene id: 698758:AXY_RS10170
uniprot id: K0J7X8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

698758:AXY RS03080
gene id: 698758:AXY_RS03080
uniprot id: K0J2I3
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

698758:AXY RS08590
gene id: 698758:AXY_RS08590
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS07715
gene id: 698758:AXY_RS07715
uniprot id: K0J3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

698758:AXY RS09175
gene id: 698758:AXY_RS09175
uniprot id: K0IZL1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

698758:AXY RS01525
gene id: 698758:AXY_RS01525
uniprot id: K0IVD9
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

698758:AXY RS00650
gene id: 698758:AXY_RS00650
uniprot id: K0IZ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

698758:AXY RS11040
gene id: 698758:AXY_RS11040
uniprot id: K0J0D3
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

698758:AXY RS08345
gene id: 698758:AXY_RS08345
uniprot id: K0J7Q3
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS01400
gene id: 698758:AXY_RS01400
uniprot id: K0IVC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

698758:AXY RS09010
gene id: 698758:AXY_RS09010
uniprot id: K0IZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05595
gene id: 698758:AXY_RS05595
uniprot id: K0J7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

698758:AXY RS08105
gene id: 698758:AXY_RS08105
uniprot id: K0IYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

698758:AXY RS01675
gene id: 698758:AXY_RS01675
uniprot id: K0IVG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

698758:AXY RS11340
gene id: 698758:AXY_RS11340
uniprot id: K0J4T8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

698758:AXY RS11380
gene id: 698758:AXY_RS11380
uniprot id: K0J5S0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

698758:AXY RS11705
gene id: 698758:AXY_RS11705
uniprot id: K0J841
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

698758:AXY RS07520
gene id: 698758:AXY_RS07520
uniprot id: K0J7M0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

698758:AXY RS09590
gene id: 698758:AXY_RS09590
uniprot id: K0J480
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

698758:AXY RS06095
gene id: 698758:AXY_RS06095
uniprot id: K0J2C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

698758:AXY RS08880
gene id: 698758:AXY_RS08880
uniprot id: K0J7S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

698758:AXY RS07980
gene id: 698758:AXY_RS07980
uniprot id: K0IYT4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

698758:AXY RS08825
gene id: 698758:AXY_RS08825
uniprot id: K0J3W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

698758:AXY RS01725
gene id: 698758:AXY_RS01725
uniprot id: K0IVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS05770
gene id: 698758:AXY_RS05770
uniprot id: K0J7B6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

698758:AXY RS04235
gene id: 698758:AXY_RS04235
uniprot id: K0J6X2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

698758:AXY RS00910
gene id: 698758:AXY_RS00910
uniprot id: K0IVA4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS05175
gene id: 698758:AXY_RS05175
uniprot id: K0J3K0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

698758:AXY RS08065
gene id: 698758:AXY_RS08065
uniprot id: K0J3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

698758:AXY RS00300
gene id: 698758:AXY_RS00300
uniprot id: K0IYY6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07685
gene id: 698758:AXY_RS07685
uniprot id: K0J4J3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

698758:AXY RS00755
gene id: 698758:AXY_RS00755
uniprot id: K0J5Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

698758:AXY RS12110
gene id: 698758:AXY_RS12110
uniprot id: K0J548
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

698758:AXY RS01415
gene id: 698758:AXY_RS01415
uniprot id: K0IZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

698758:AXY RS07280
gene id: 698758:AXY_RS07280
uniprot id: K0IYL9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

698758:AXY RS06470
gene id: 698758:AXY_RS06470
uniprot id: K0J7G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

698758:AXY RS04855
gene id: 698758:AXY_RS04855
uniprot id: K0IXE3
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS10465
gene id: 698758:AXY_RS10465
uniprot id: K0J042
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

698758:AXY RS00955
gene id: 698758:AXY_RS00955
uniprot id: K0IV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

698758:AXY RS10665
gene id: 698758:AXY_RS10665
uniprot id: K0J073
names: Similarity
messages: Belongs to the TrpF family.

698758:AXY RS04740
gene id: 698758:AXY_RS04740
uniprot id: K0J378
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

698758:AXY RS09785
gene id: 698758:AXY_RS09785
uniprot id: K0J7W2
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

698758:AXY RS07800
gene id: 698758:AXY_RS07800
uniprot id: K0IYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

698758:AXY RS10460
gene id: 698758:AXY_RS10460
uniprot id: K0J072
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS07955
gene id: 698758:AXY_RS07955
uniprot id: K0IYT1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS10715
gene id: 698758:AXY_RS10715
uniprot id: K0J086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03185
gene id: 698758:AXY_RS03185
uniprot id: K0J0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

698758:AXY RS07805
gene id: 698758:AXY_RS07805
uniprot id: K0IYR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

698758:AXY RS10930
gene id: 698758:AXY_RS10930
uniprot id: K0J808
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

698758:AXY RS00785
gene id: 698758:AXY_RS00785
uniprot id: K0IV36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS04865
gene id: 698758:AXY_RS04865
uniprot id: K0J3A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

698758:AXY RS07010
gene id: 698758:AXY_RS07010
uniprot id: K0J7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

698758:AXY RS09320
gene id: 698758:AXY_RS09320
uniprot id: K0J7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

698758:AXY RS00130
gene id: 698758:AXY_RS00130
uniprot id: K0IYU5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS08110
gene id: 698758:AXY_RS08110
uniprot id: K0J4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

698758:AXY RS05685
gene id: 698758:AXY_RS05685
uniprot id: K0J3S7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

698758:AXY RS05015
gene id: 698758:AXY_RS05015
uniprot id: K0J3F1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

698758:AXY RS02735
gene id: 698758:AXY_RS02735
uniprot id: K0IW40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

698758:AXY RS11570
gene id: 698758:AXY_RS11570
uniprot id: K0J0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05270
gene id: 698758:AXY_RS05270
uniprot id: K0J3L4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

698758:AXY RS00205
gene id: 698758:AXY_RS00205
uniprot id: K0IYW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09830
gene id: 698758:AXY_RS09830
uniprot id: K0J4B9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

698758:AXY RS11925
gene id: 698758:AXY_RS11925
uniprot id: K0J0W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS01815
gene id: 698758:AXY_RS01815
uniprot id: K0J625
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS03270
gene id: 698758:AXY_RS03270
uniprot id: K0J6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

698758:AXY RS11145
gene id: 698758:AXY_RS11145
uniprot id: K0J4R2
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

698758:AXY RS06515
gene id: 698758:AXY_RS06515
uniprot id: K0J2M9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

698758:AXY RS09790
gene id: 698758:AXY_RS09790
uniprot id: K0IZV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

698758:AXY RS10025
gene id: 698758:AXY_RS10025
uniprot id: K0J005
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

698758:AXY RS10385
gene id: 698758:AXY_RS10385
uniprot id: K0J050
names: Similarity
messages: Belongs to the LacAB/RpiB family.

698758:AXY RS05135
gene id: 698758:AXY_RS05135
uniprot id: K0J770
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

698758:AXY RS11020
gene id: 698758:AXY_RS11020
uniprot id: K0J5N3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06600
gene id: 698758:AXY_RS06600
uniprot id: K0IY34
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

698758:AXY RS08760
gene id: 698758:AXY_RS08760
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS03100
gene id: 698758:AXY_RS03100
uniprot id: K0IW89
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06085
gene id: 698758:AXY_RS06085
uniprot id: K0IXT9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

698758:AXY RS02340
gene id: 698758:AXY_RS02340
uniprot id: K0IVV6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

698758:AXY RS03000
gene id: 698758:AXY_RS03000
uniprot id: K0IWI8
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family.

698758:AXY RS05615
gene id: 698758:AXY_RS05615
uniprot id: K0J260
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS04405
gene id: 698758:AXY_RS04405
uniprot id: K0J1H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

698758:AXY RS00850
gene id: 698758:AXY_RS00850
uniprot id: K0IZ82
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS10855
gene id: 698758:AXY_RS10855
uniprot id: K0J805
names: Similarity
messages: Belongs to the UPF0047 family.

698758:AXY RS03645
gene id: 698758:AXY_RS03645
uniprot id: K0IWH1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

698758:AXY RS07785
gene id: 698758:AXY_RS07785
uniprot id: K0J4K1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

698758:AXY RS00695
gene id: 698758:AXY_RS00695
uniprot id: K0J180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS10745
gene id: 698758:AXY_RS10745
uniprot id: K0J5K3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

698758:AXY RS02540
gene id: 698758:AXY_RS02540
uniprot id: K0J2B7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

698758:AXY RS00595
gene id: 698758:AXY_RS00595
uniprot id: K0IV72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

698758:AXY RS05495
gene id: 698758:AXY_RS05495
uniprot id: K0J247
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

698758:AXY RS10795
gene id: 698758:AXY_RS10795
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS08240
gene id: 698758:AXY_RS08240
uniprot id: K0J3M2
names: Similarity
messages: Belongs to the UPF0223 family.

698758:AXY RS10425
gene id: 698758:AXY_RS10425
uniprot id: K0J4I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

698758:AXY RS07305
gene id: 698758:AXY_RS07305
uniprot id: K0IYM2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

698758:AXY RS07575
gene id: 698758:AXY_RS07575
uniprot id: K0IYU6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

698758:AXY RS00725
gene id: 698758:AXY_RS00725
uniprot id: K0IZ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS10050
gene id: 698758:AXY_RS10050
uniprot id: K0J008
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

698758:AXY RS01715
gene id: 698758:AXY_RS01715
uniprot id: K0IZS0
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS10005
gene id: 698758:AXY_RS10005
uniprot id: K0IZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

698758:AXY RS06110
gene id: 698758:AXY_RS06110
uniprot id: K0IXU4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

698758:AXY RS09690
gene id: 698758:AXY_RS09690
uniprot id: K0J499
names: Similarity
messages: Belongs to the transpeptidase family.

698758:AXY RS08415
gene id: 698758:AXY_RS08415
uniprot id: K0J3P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

698758:AXY RS05700
gene id: 698758:AXY_RS05700
uniprot id: K0IXV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

698758:AXY RS04745
gene id: 698758:AXY_RS04745
uniprot id: K0J1Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS03440
gene id: 698758:AXY_RS03440
uniprot id: K0J2L1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

698758:AXY RS00795
gene id: 698758:AXY_RS00795
uniprot id: K0J1A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS04960
gene id: 698758:AXY_RS04960
uniprot id: K0IXA4
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07445
gene id: 698758:AXY_RS07445
uniprot id: K0J7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

698758:AXY RS00690
gene id: 698758:AXY_RS00690
uniprot id: K0IV82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

698758:AXY RS02295
gene id: 698758:AXY_RS02295
uniprot id: K0J250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

698758:AXY RS07435
gene id: 698758:AXY_RS07435
uniprot id: K0J4F8
names: Similarity
messages: Belongs to the ribF family.

698758:AXY RS06770
gene id: 698758:AXY_RS06770
uniprot id: K0IY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

698758:AXY RS08010
gene id: 698758:AXY_RS08010
uniprot id: K0J4M8
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS00225
gene id: 698758:AXY_RS00225
uniprot id: K0J134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

698758:AXY RS01650
gene id: 698758:AXY_RS01650
uniprot id: K0IVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03720
gene id: 698758:AXY_RS03720
uniprot id: K0IWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS10675
gene id: 698758:AXY_RS10675
uniprot id: K0J4K3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS04320
gene id: 698758:AXY_RS04320
uniprot id: K0J6Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

698758:AXY RS07490
gene id: 698758:AXY_RS07490
uniprot id: K0J3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

698758:AXY RS04430
gene id: 698758:AXY_RS04430
uniprot id: K0J1I1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

698758:AXY RS00675
gene id: 698758:AXY_RS00675
uniprot id: K0IZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

698758:AXY RS03090
gene id: 698758:AXY_RS03090
uniprot id: K0J6K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

698758:AXY RS05145
gene id: 698758:AXY_RS05145
uniprot id: K0IXG4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

698758:AXY RS05200
gene id: 698758:AXY_RS05200
uniprot id: K0J3K5
names: Similarity
messages: Belongs to the GSP E family.

698758:AXY RS07765
gene id: 698758:AXY_RS07765
uniprot id: K0J3G1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

698758:AXY RS02435
gene id: 698758:AXY_RS02435
uniprot id: K0IW52
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

698758:AXY RS01835
gene id: 698758:AXY_RS01835
uniprot id: K0IZV1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

698758:AXY RS02825
gene id: 698758:AXY_RS02825
uniprot id: K0J6I0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

698758:AXY RS11035
gene id: 698758:AXY_RS11035
uniprot id: K0J0I6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

698758:AXY RS04240
gene id: 698758:AXY_RS04240
uniprot id: K0IX30
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

698758:AXY RS04955
gene id: 698758:AXY_RS04955
uniprot id: K0IXG2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS07775
gene id: 698758:AXY_RS07775
uniprot id: K0IYY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

698758:AXY RS08045
gene id: 698758:AXY_RS08045
uniprot id: K0J7P1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

698758:AXY RS03655
gene id: 698758:AXY_RS03655
uniprot id: K0J0Y5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

698758:AXY RS05090
gene id: 698758:AXY_RS05090
uniprot id: K0J3I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

698758:AXY RS09095
gene id: 698758:AXY_RS09095
uniprot id: K0J400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

698758:AXY RS04075
gene id: 698758:AXY_RS04075
uniprot id: K0J2W0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS07355
gene id: 698758:AXY_RS07355
uniprot id: K0IYM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

698758:AXY RS08755
gene id: 698758:AXY_RS08755
uniprot id: K0J7S0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

698758:AXY RS08900
gene id: 698758:AXY_RS08900
uniprot id: K0J3X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS05290
gene id: 698758:AXY_RS05290
uniprot id: K0IXI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

698758:AXY RS01620
gene id: 698758:AXY_RS01620
uniprot id: K0J601
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

698758:AXY RS03625
gene id: 698758:AXY_RS03625
uniprot id: K0J2P1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

698758:AXY RS02145
gene id: 698758:AXY_RS02145
uniprot id: K0J226
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

698758:AXY RS11985
gene id: 698758:AXY_RS11985
uniprot id: K0J533
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

698758:AXY RS05730
gene id: 698758:AXY_RS05730
uniprot id: K0IXN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

698758:AXY RS01615
gene id: 698758:AXY_RS01615
uniprot id: K0IZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

698758:AXY RS02890
gene id: 698758:AXY_RS02890
uniprot id: K0J2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

698758:AXY RS00940
gene id: 698758:AXY_RS00940
uniprot id: K0J1D0
names: Similarity
messages: Belongs to the manganese catalase family.

698758:AXY RS07645
gene id: 698758:AXY_RS07645
uniprot id: K0J7M5
names: Similarity
messages: Belongs to the FlgD family.

698758:AXY RS11955
gene id: 698758:AXY_RS11955
uniprot id: K0J5Y7
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS10915
gene id: 698758:AXY_RS10915
uniprot id: K0J0B6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

698758:AXY RS06910
gene id: 698758:AXY_RS06910
uniprot id: K0J7J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

698758:AXY RS09640
gene id: 698758:AXY_RS09640
uniprot id: K0J488
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS08970
gene id: 698758:AXY_RS08970
uniprot id: K0J3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

698758:AXY RS12050
gene id: 698758:AXY_RS12050
uniprot id: K0J0Y3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

698758:AXY RS03490
gene id: 698758:AXY_RS03490
uniprot id: K0J0V9
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS11365
gene id: 698758:AXY_RS11365
uniprot id: K0J826
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

698758:AXY RS04360
gene id: 698758:AXY_RS04360
uniprot id: K0J6Y7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

698758:AXY RS04325
gene id: 698758:AXY_RS04325
uniprot id: K0IX50
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

698758:AXY RS07495
gene id: 698758:AXY_RS07495
uniprot id: K0J7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

698758:AXY RS01470
gene id: 698758:AXY_RS01470
uniprot id: K0J5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS09000
gene id: 698758:AXY_RS09000
uniprot id: K0J3Y5
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS00735
gene id: 698758:AXY_RS00735
uniprot id: K0IV29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

698758:AXY RS06100
gene id: 698758:AXY_RS06100
uniprot id: K0J7D8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

698758:AXY RS00625
gene id: 698758:AXY_RS00625
uniprot id: K0IZ38
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

698758:AXY RS06595
gene id: 698758:AXY_RS06595
uniprot id: K0IY98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS07860
gene id: 698758:AXY_RS07860
uniprot id: K0J4K8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

698758:AXY RS10765
gene id: 698758:AXY_RS10765
uniprot id: K0J096
names: Similarity
messages: Belongs to the peptidase S11 family.

698758:AXY RS09510
gene id: 698758:AXY_RS09510
uniprot id: K0IZR2
names: Similarity
messages: Belongs to the PspA/IM30 family.

698758:AXY RS10655
gene id: 698758:AXY_RS10655
uniprot id: K0J7Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

698758:AXY RS01335
gene id: 698758:AXY_RS01335
uniprot id: K0IVE0
names: Similarity
messages: Belongs to the LOR family.

698758:AXY RS05300
gene id: 698758:AXY_RS05300
uniprot id: K0J222
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

698758:AXY RS09235
gene id: 698758:AXY_RS09235
uniprot id: K0J516
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS11640
gene id: 698758:AXY_RS11640
uniprot id: K0J838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

698758:AXY RS06320
gene id: 698758:AXY_RS06320
uniprot id: K0J2I5
names: Similarity
messages: Belongs to the SleB family.

698758:AXY RS00360
gene id: 698758:AXY_RS00360
uniprot id: K0IUZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

698758:AXY RS03125
gene id: 698758:AXY_RS03125
uniprot id: K0IW92
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS01750
gene id: 698758:AXY_RS01750
uniprot id: K0IVH6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS12035
gene id: 698758:AXY_RS12035
uniprot id: K0J538
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

698758:AXY RS00445
gene id: 698758:AXY_RS00445
uniprot id: K0IV66
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

698758:AXY RS01560
gene id: 698758:AXY_RS01560
uniprot id: K0J1R9
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS09360
gene id: 698758:AXY_RS09360
uniprot id: K0IZN9
names: Similarity
messages: Belongs to the UPF0342 family.

698758:AXY RS06520
gene id: 698758:AXY_RS06520
uniprot id: K0J7G9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS12115
gene id: 698758:AXY_RS12115
uniprot id: K0J858
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

698758:AXY RS10805
gene id: 698758:AXY_RS10805
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS04120
gene id: 698758:AXY_RS04120
uniprot id: K0IWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

698758:AXY RS08060
gene id: 698758:AXY_RS08060
uniprot id: K0J4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

698758:AXY RS05650
gene id: 698758:AXY_RS05650
uniprot id: K0IXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

698758:AXY RS08560
gene id: 698758:AXY_RS08560
uniprot id: K0J3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

698758:AXY RS02315
gene id: 698758:AXY_RS02315
uniprot id: K0IVV2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

698758:AXY RS08125
gene id: 698758:AXY_RS08125
uniprot id: K0IZ33
names: Similarity
messages: Belongs to the transpeptidase family.

698758:AXY RS10810
gene id: 698758:AXY_RS10810
uniprot id: K0J0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

698758:AXY RS01310
gene id: 698758:AXY_RS01310
uniprot id: K0IVD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

698758:AXY RS04645
gene id: 698758:AXY_RS04645
uniprot id: K0J707
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

698758:AXY RS11375
gene id: 698758:AXY_RS11375
uniprot id: K0J0J2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

698758:AXY RS02360
gene id: 698758:AXY_RS02360
uniprot id: K0IW16
names: Similarity
messages: Belongs to the GARS family.

698758:AXY RS07915
gene id: 698758:AXY_RS07915
uniprot id: K0J4L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

698758:AXY RS07975
gene id: 698758:AXY_RS07975
uniprot id: K0IZ10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

698758:AXY RS06155
gene id: 698758:AXY_RS06155
uniprot id: K0IXV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

698758:AXY RS05955
gene id: 698758:AXY_RS05955
uniprot id: K0IXZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS02425
gene id: 698758:AXY_RS02425
uniprot id: K0J078
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

698758:AXY RS00715
gene id: 698758:AXY_RS00715
uniprot id: K0IV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

698758:AXY RS04465
gene id: 698758:AXY_RS04465
uniprot id: K0IX79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

698758:AXY RS07205
gene id: 698758:AXY_RS07205
uniprot id: K0IYK8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

698758:AXY RS07000
gene id: 698758:AXY_RS07000
uniprot id: K0J4A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

698758:AXY RS00265
gene id: 698758:AXY_RS00265
uniprot id: K0IV51
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS02445
gene id: 698758:AXY_RS02445
uniprot id: K0J287
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

698758:AXY RS02350
gene id: 698758:AXY_RS02350
uniprot id: K0J055
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

698758:AXY RS08405
gene id: 698758:AXY_RS08405
uniprot id: K0IZ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

698758:AXY RS07580
gene id: 698758:AXY_RS07580
uniprot id: K0IYN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

698758:AXY RS12030
gene id: 698758:AXY_RS12030
uniprot id: K0J5Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

698758:AXY RS11185
gene id: 698758:AXY_RS11185
uniprot id: K0J0F6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

698758:AXY RS10415
gene id: 698758:AXY_RS10415
uniprot id: K0J038
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

698758:AXY RS05400
gene id: 698758:AXY_RS05400
uniprot id: K0J236
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

698758:AXY RS03545
gene id: 698758:AXY_RS03545
uniprot id: K0IWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

698758:AXY RS07670
gene id: 698758:AXY_RS07670
uniprot id: K0J7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

698758:AXY RS02325
gene id: 698758:AXY_RS02325
uniprot id: K0J046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

698758:AXY RS10555
gene id: 698758:AXY_RS10555
uniprot id: K0J7Z3
names: Similarity
messages: Belongs to the peptidase M29 family.

698758:AXY RS09265
gene id: 698758:AXY_RS09265
uniprot id: K0J428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

698758:AXY RS00670
gene id: 698758:AXY_RS00670
uniprot id: K0J177
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

698758:AXY RS00775
gene id: 698758:AXY_RS00775
uniprot id: K0IZ65
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

698758:AXY RS07635
gene id: 698758:AXY_RS07635
uniprot id: K0J4I8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

698758:AXY RS04335
gene id: 698758:AXY_RS04335
uniprot id: K0J1G2
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS06205
gene id: 698758:AXY_RS06205
uniprot id: K0IY32
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

698758:AXY RS03495
gene id: 698758:AXY_RS03495
uniprot id: K0J6P2
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS05205
gene id: 698758:AXY_RS05205
uniprot id: K0J209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

698758:AXY RS07770
gene id: 698758:AXY_RS07770
uniprot id: K0J7N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

698758:AXY RS10105
gene id: 698758:AXY_RS10105
uniprot id: K0IZZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

698758:AXY RS02380
gene id: 698758:AXY_RS02380
uniprot id: K0J6A7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS00745
gene id: 698758:AXY_RS00745
uniprot id: K0J192
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

698758:AXY RS03095
gene id: 698758:AXY_RS03095
uniprot id: K0IWK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

698758:AXY RS05420
gene id: 698758:AXY_RS05420
uniprot id: K0J3N8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

698758:AXY RS07755
gene id: 698758:AXY_RS07755
uniprot id: K0IYQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

698758:AXY RS02020
gene id: 698758:AXY_RS02020
uniprot id: K0IVP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

698758:AXY RS09285
gene id: 698758:AXY_RS09285
uniprot id: K0J520
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

698758:AXY RS05885
gene id: 698758:AXY_RS05885
uniprot id: K0J431
names: Similarity
messages: Belongs to the UPF0236 family.

698758:AXY RS00410
gene id: 698758:AXY_RS00410
uniprot id: K0J5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

698758:AXY RS10230
gene id: 698758:AXY_RS10230
uniprot id: K0J025
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS00415
gene id: 698758:AXY_RS00415
uniprot id: K0IV02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

698758:AXY RS05935
gene id: 698758:AXY_RS05935
uniprot id: K0IXR3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

698758:AXY RS07505
gene id: 698758:AXY_RS07505
uniprot id: K0IYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

698758:AXY RS02355
gene id: 698758:AXY_RS02355
uniprot id: K0J6A0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

698758:AXY RS05675
gene id: 698758:AXY_RS05675
uniprot id: K0IXV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

698758:AXY RS03595
gene id: 698758:AXY_RS03595
uniprot id: K0IWG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

698758:AXY RS08220
gene id: 698758:AXY_RS08220
uniprot id: K0J7P8
names: Similarity
messages: Belongs to the UPF0358 family.

698758:AXY RS01695
gene id: 698758:AXY_RS01695
uniprot id: K0J609
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

698758:AXY RS00580
gene id: 698758:AXY_RS00580
uniprot id: K0IZ28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

698758:AXY RS11980
gene id: 698758:AXY_RS11980
uniprot id: K0J5Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

698758:AXY RS06480
gene id: 698758:AXY_RS06480
uniprot id: K0IY12
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

698758:AXY RS00640
gene id: 698758:AXY_RS00640
uniprot id: K0IV76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

698758:AXY RS02430
gene id: 698758:AXY_RS02430
uniprot id: K0J6B9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

698758:AXY RS05665
gene id: 698758:AXY_RS05665
uniprot id: K0J266
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

698758:AXY RS10325
gene id: 698758:AXY_RS10325
uniprot id: K0J4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

698758:AXY RS10570
gene id: 698758:AXY_RS10570
uniprot id: K0J5I3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

698758:AXY RS06850
gene id: 698758:AXY_RS06850
uniprot id: K0J495
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

698758:AXY RS04250
gene id: 698758:AXY_RS04250
uniprot id: K0J2Y4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

698758:AXY RS07625
gene id: 698758:AXY_RS07625
uniprot id: K0IYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

698758:AXY RS06315
gene id: 698758:AXY_RS06315
uniprot id: K0J411
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Homodimer.

698758:AXY RS08170
gene id: 698758:AXY_RS08170
uniprot id: K0J7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

698758:AXY RS09120
gene id: 698758:AXY_RS09120
uniprot id: K0J403
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS07260
gene id: 698758:AXY_RS07260
uniprot id: K0IYG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

698758:AXY RS06610
gene id: 698758:AXY_RS06610
uniprot id: K0J2P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

698758:AXY RS02330
gene id: 698758:AXY_RS02330
uniprot id: K0J694
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

698758:AXY RS05120
gene id: 698758:AXY_RS05120
uniprot id: K0IXG0
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

698758:AXY RS00355
gene id: 698758:AXY_RS00355
uniprot id: K0J5L3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

698758:AXY RS08830
gene id: 698758:AXY_RS08830
uniprot id: K0J7S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

698758:AXY RS02785
gene id: 698758:AXY_RS02785
uniprot id: K0IW47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

698758:AXY RS12045
gene id: 698758:AXY_RS12045
uniprot id: K0J175
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

698758:AXY RS00835
gene id: 698758:AXY_RS00835
uniprot id: K0IV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

698758:AXY RS08085
gene id: 698758:AXY_RS08085
uniprot id: K0J4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

698758:AXY RS10235
gene id: 698758:AXY_RS10235
uniprot id: K0J010
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS12025
gene id: 698758:AXY_RS12025
uniprot id: K0J0Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

698758:AXY RS07905
gene id: 698758:AXY_RS07905
uniprot id: K0IYZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

698758:AXY RS00140
gene id: 698758:AXY_RS00140
uniprot id: K0IUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS11860
gene id: 698758:AXY_RS11860
uniprot id: K0J5X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

698758:AXY RS12020
gene id: 698758:AXY_RS12020
uniprot id: K0J170
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

698758:AXY RS01980
gene id: 698758:AXY_RS01980
uniprot id: K0IZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

698758:AXY RS09460
gene id: 698758:AXY_RS09460
uniprot id: K0IZQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

698758:AXY RS04065
gene id: 698758:AXY_RS04065
uniprot id: K0IWZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

698758:AXY RS00255
gene id: 698758:AXY_RS00255
uniprot id: K0J5K4
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

698758:AXY RS02805
gene id: 698758:AXY_RS02805
uniprot id: K0IWG0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

698758:AXY RS09825
gene id: 698758:AXY_RS09825
uniprot id: K0J590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

698758:AXY RS08790
gene id: 698758:AXY_RS08790
uniprot id: K0IZ83
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS06935
gene id: 698758:AXY_RS06935
uniprot id: K0J7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

698758:AXY RS08160
gene id: 698758:AXY_RS08160
uniprot id: K0J4P4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

698758:AXY RS07875
gene id: 698758:AXY_RS07875
uniprot id: K0J7N4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS00820
gene id: 698758:AXY_RS00820
uniprot id: K0J1A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

698758:AXY RS04750
gene id: 698758:AXY_RS04750
uniprot id: K0J721
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

698758:AXY RS02115
gene id: 698758:AXY_RS02115
uniprot id: K0IVR8
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08115
gene id: 698758:AXY_RS08115
uniprot id: K0J3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

698758:AXY RS01740
gene id: 698758:AXY_RS01740
uniprot id: K0IZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

698758:AXY RS00260
gene id: 698758:AXY_RS00260
uniprot id: K0IUY9
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

698758:AXY RS01660
gene id: 698758:AXY_RS01660
uniprot id: K0J1U4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

698758:AXY RS06975
gene id: 698758:AXY_RS06975
uniprot id: K0J4A8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

698758:AXY RS07835
gene id: 698758:AXY_RS07835
uniprot id: K0J4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

698758:AXY RS05095
gene id: 698758:AXY_RS05095
uniprot id: K0J1Z5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

698758:AXY RS06970
gene id: 698758:AXY_RS06970
uniprot id: K0IYA7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

698758:AXY RS08500
gene id: 698758:AXY_RS08500
uniprot id: K0IZ21
names: Subcellular Location Annotation
messages: Cell membrane

698758:AXY RS09335
gene id: 698758:AXY_RS09335
uniprot id: K0J528
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

698758:AXY RS01735
gene id: 698758:AXY_RS01735
uniprot id: K0J1W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

698758:AXY RS02830
gene id: 698758:AXY_RS02830
uniprot id: K0IWG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

698758:AXY RS03630
gene id: 698758:AXY_RS03630
uniprot id: K0J0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

698758:AXY RS10015
gene id: 698758:AXY_RS10015
uniprot id: K0J4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

698758:AXY RS10775
gene id: 698758:AXY_RS10775
uniprot id: K0J4L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

698758:AXY RS04655
gene id: 698758:AXY_RS04655
uniprot id: K0IX57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

698758:AXY RS01875
gene id: 698758:AXY_RS01875
uniprot id: K0IVN8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

698758:AXY RS05185
gene id: 698758:AXY_RS05185
uniprot id: K0J774
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Required for transformation and DNA binding.

698758:AXY RS01330
gene id: 698758:AXY_RS01330
uniprot id: K0IVB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

698758:AXY RS05130
gene id: 698758:AXY_RS05130
uniprot id: K0J1Z8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

698758:AXY RS07275
gene id: 698758:AXY_RS07275
uniprot id: K0J7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

698758:AXY RS02440
gene id: 698758:AXY_RS02440
uniprot id: K0IVX8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

698758:AXY RS07070
gene id: 698758:AXY_RS07070
uniprot id: K0IYC5
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

698758:AXY RS07920
gene id: 698758:AXY_RS07920
uniprot id: K0J3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

698758:AXY RS04890
gene id: 698758:AXY_RS04890
uniprot id: K0J3B5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

698758:AXY RS01380
gene id: 698758:AXY_RS01380
uniprot id: K0IVE5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

698758:AXY RS08545
gene id: 698758:AXY_RS08545
uniprot id: K0IZ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

698758:AXY RS08000
gene id: 698758:AXY_RS08000
uniprot id: K0IZ14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

698758:AXY RS06220
gene id: 698758:AXY_RS06220
uniprot id: K0J2F9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

698758:AXY RS07425
gene id: 698758:AXY_RS07425
uniprot id: K0IYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

698758:AXY RS06185
gene id: 698758:AXY_RS06185
uniprot id: K0J3Z4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the MPD complex composed of SpoIIM, SpoIIP and SpoIID.
messages: Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.

698758:AXY RS04870
gene id: 698758:AXY_RS04870
uniprot id: K0J1T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

698758:AXY RS04815
gene id: 698758:AXY_RS04815
uniprot id: K0J396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

698758:AXY RS03155
gene id: 698758:AXY_RS03155
uniprot id: K0J2J1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS02745
gene id: 698758:AXY_RS02745
uniprot id: K0J0I5
names: Similarity
messages: Belongs to the peptidase C59 family.

698758:AXY RS09395
gene id: 698758:AXY_RS09395
uniprot id: K0J536
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS06050
gene id: 698758:AXY_RS06050
uniprot id: K0J7D4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

698758:AXY RS06645
gene id: 698758:AXY_RS06645
uniprot id: K0IYA5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

698758:AXY RS04545
gene id: 698758:AXY_RS04545
uniprot id: K0J1K0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

698758:AXY RS08135
gene id: 698758:AXY_RS08135
uniprot id: K0J4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

698758:AXY RS05825
gene id: 698758:AXY_RS05825
uniprot id: K0IXX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS05360
gene id: 698758:AXY_RS05360
uniprot id: K0IXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

698758:AXY RS10625
gene id: 698758:AXY_RS10625
uniprot id: K0J4J8
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

698758:AXY RS03480
gene id: 698758:AXY_RS03480
uniprot id: K0IWE1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS10575
gene id: 698758:AXY_RS10575
uniprot id: K0J4J2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

698758:AXY RS10755
gene id: 698758:AXY_RS10755
uniprot id: K0J801
names: Similarity
messages: Belongs to the aldose epimerase family.

698758:AXY RS09115
gene id: 698758:AXY_RS09115
uniprot id: K0J502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS10660
gene id: 698758:AXY_RS10660
uniprot id: K0J0A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

698758:AXY RS06055
gene id: 698758:AXY_RS06055
uniprot id: K0IY06
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

698758:AXY RS02645
gene id: 698758:AXY_RS02645
uniprot id: K0J2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS03255
gene id: 698758:AXY_RS03255
uniprot id: K0IWB1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

698758:AXY RS11125
gene id: 698758:AXY_RS11125
uniprot id: K0J4Q8
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer; disulfide-linked, upon oxidation (PubMed:10960086, PubMed:15770647). 5 homodimers assemble to form a ring-like decamer (PubMed:15770647).
messages: Induced significantly under aerobic conditions.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this typical 2-Cys peroxiredoxin, C(R) is provided by the other dimeric subunit to form an intersubunit disulfide (PubMed:15770647). The disulfide is subsequently reduced by AhpF (By similarity).
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

698758:AXY RS07780
gene id: 698758:AXY_RS07780
uniprot id: K0IYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

698758:AXY RS10985
gene id: 698758:AXY_RS10985
uniprot id: K0J0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

698758:AXY RS07910
gene id: 698758:AXY_RS07910
uniprot id: K0IYS5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09800
gene id: 698758:AXY_RS09800
uniprot id: K0J585
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

698758:AXY RS05560
gene id: 698758:AXY_RS05560
uniprot id: K0IXL2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

698758:AXY RS10475
gene id: 698758:AXY_RS10475
uniprot id: K0J4I4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS00340
gene id: 698758:AXY_RS00340
uniprot id: K0IV58
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

698758:AXY RS06280
gene id: 698758:AXY_RS06280
uniprot id: K0IY44
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS02765
gene id: 698758:AXY_RS02765
uniprot id: K0J2E7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS04820
gene id: 698758:AXY_RS04820
uniprot id: K0J1S2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS00550
gene id: 698758:AXY_RS00550
uniprot id: K0J164
names: Similarity
messages: Belongs to the CtsR family.

698758:AXY RS10270
gene id: 698758:AXY_RS10270
uniprot id: K0J4H4
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08420
gene id: 698758:AXY_RS08420
uniprot id: K0J7Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

698758:AXY RS08815
gene id: 698758:AXY_RS08815
uniprot id: K0IZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

698758:AXY RS00720
gene id: 698758:AXY_RS00720
uniprot id: K0J184
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

698758:AXY RS10480
gene id: 698758:AXY_RS10480
uniprot id: K0J7Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS04125
gene id: 698758:AXY_RS04125
uniprot id: K0J2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

698758:AXY RS10115
gene id: 698758:AXY_RS10115
uniprot id: K0J4G2
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS03195
gene id: 698758:AXY_RS03195
uniprot id: K0IWL6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

698758:AXY RS10840
gene id: 698758:AXY_RS10840
uniprot id: K0J0A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

698758:AXY RS00435
gene id: 698758:AXY_RS00435
uniprot id: K0J5M1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

698758:AXY RS02335
gene id: 698758:AXY_RS02335
uniprot id: K0IW10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

698758:AXY RS09240
gene id: 698758:AXY_RS09240
uniprot id: K0J424
names: Subcellular Location Annotation
messages: cell wall

698758:AXY RS00590
gene id: 698758:AXY_RS00590
uniprot id: K0IV10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS10210
gene id: 698758:AXY_RS10210
uniprot id: K0J007
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

698758:AXY RS08175
gene id: 698758:AXY_RS08175
uniprot id: K0IZ39
names: Similarity
messages: Belongs to the peptidase S16 family.

698758:AXY RS05585
gene id: 698758:AXY_RS05585
uniprot id: K0J3R2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

698758:AXY RS10185
gene id: 698758:AXY_RS10185
uniprot id: K0J004
names: Similarity
messages: Belongs to the CpsD/CapB family.

698758:AXY RS00005
gene id: 698758:AXY_RS00005
uniprot id: K0J5H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

698758:AXY RS07385
gene id: 698758:AXY_RS07385
uniprot id: K0J4F2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

698758:AXY RS07270
gene id: 698758:AXY_RS07270
uniprot id: K0J344
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

698758:AXY RS04015
gene id: 698758:AXY_RS04015
uniprot id: K0IWY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

698758:AXY RS00290
gene id: 698758:AXY_RS00290
uniprot id: K0IV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

698758:AXY RS00220
gene id: 698758:AXY_RS00220
uniprot id: K0IV46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

698758:AXY RS06070
gene id: 698758:AXY_RS06070
uniprot id: K0J2B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

698758:AXY RS11540
gene id: 698758:AXY_RS11540
uniprot id: K0J834
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

698758:AXY RS08400
gene id: 698758:AXY_RS08400
uniprot id: K0IZ70
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS11315
gene id: 698758:AXY_RS11315
uniprot id: K0J4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05890
gene id: 698758:AXY_RS05890
uniprot id: K0J3V1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

698758:AXY RS04190
gene id: 698758:AXY_RS04190
uniprot id: K0IX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

698758:AXY RS09915
gene id: 698758:AXY_RS09915
uniprot id: K0J5B5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

698758:AXY RS07985
gene id: 698758:AXY_RS07985
uniprot id: K0J4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

698758:AXY RS06360
gene id: 698758:AXY_RS06360
uniprot id: K0IXY9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

698758:AXY RS04635
gene id: 698758:AXY_RS04635
uniprot id: K0J355
names: Similarity
messages: Belongs to the UPF0354 family.

698758:AXY RS04715
gene id: 698758:AXY_RS04715
uniprot id: K0J371
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

698758:AXY RS04840
gene id: 698758:AXY_RS04840
uniprot id: K0J3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

698758:AXY RS11495
gene id: 698758:AXY_RS11495
uniprot id: K0J832
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

698758:AXY RS10245
gene id: 698758:AXY_RS10245
uniprot id: K0J4H2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

698758:AXY RS06855
gene id: 698758:AXY_RS06855
uniprot id: K0J2V2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

698758:AXY RS06365
gene id: 698758:AXY_RS06365
uniprot id: K0J418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

698758:AXY RS06630
gene id: 698758:AXY_RS06630
uniprot id: K0J461
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS04810
gene id: 698758:AXY_RS04810
uniprot id: K0IX81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

698758:AXY RS07430
gene id: 698758:AXY_RS07430
uniprot id: K0IYJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

698758:AXY RS00770
gene id: 698758:AXY_RS00770
uniprot id: K0J196
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

698758:AXY RS02875
gene id: 698758:AXY_RS02875
uniprot id: K0J6I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

698758:AXY RS10320
gene id: 698758:AXY_RS10320
uniprot id: K0J5G1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

698758:AXY RS07500
gene id: 698758:AXY_RS07500
uniprot id: K0IYQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

698758:AXY RS06375
gene id: 698758:AXY_RS06375
uniprot id: K0J7F8
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

698758:AXY RS04105
gene id: 698758:AXY_RS04105
uniprot id: K0J1B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS09355
gene id: 698758:AXY_RS09355
uniprot id: K0J7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

698758:AXY RS04175
gene id: 698758:AXY_RS04175
uniprot id: K0J2X5
names: Similarity
messages: Belongs to the Fur family.

698758:AXY RS06430
gene id: 698758:AXY_RS06430
uniprot id: K0IY68
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

698758:AXY RS08570
gene id: 698758:AXY_RS08570
uniprot id: K0IZA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS05025
gene id: 698758:AXY_RS05025
uniprot id: K0J756
names: Similarity
messages: Belongs to the thioredoxin family.

698758:AXY RS00095
gene id: 698758:AXY_RS00095
uniprot id: K0IV35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

698758:AXY RS07815
gene id: 698758:AXY_RS07815
uniprot id: K0J3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

698758:AXY RS08655
gene id: 698758:AXY_RS08655
uniprot id: K0J3T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

698758:AXY RS04570
gene id: 698758:AXY_RS04570
uniprot id: K0J6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05790
gene id: 698758:AXY_RS05790
uniprot id: K0J284
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

698758:AXY RS10910
gene id: 698758:AXY_RS10910
uniprot id: K0J0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

698758:AXY RS07925
gene id: 698758:AXY_RS07925
uniprot id: K0J7N6
names: Similarity
messages: Belongs to the RemA family.

698758:AXY RS05350
gene id: 698758:AXY_RS05350
uniprot id: K0J231
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

698758:AXY RS02740
gene id: 698758:AXY_RS02740
uniprot id: K0J2E5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

698758:AXY RS11895
gene id: 698758:AXY_RS11895
uniprot id: K0J123
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS00045
gene id: 698758:AXY_RS00045
uniprot id: K0J114
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

698758:AXY RS08305
gene id: 698758:AXY_RS08305
uniprot id: K0IYY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

698758:AXY RS12105
gene id: 698758:AXY_RS12105
uniprot id: K0J5Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

698758:AXY RS10920
gene id: 698758:AXY_RS10920
uniprot id: K0J5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

698758:AXY RS03695
gene id: 698758:AXY_RS03695
uniprot id: K0IWH8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

698758:AXY RS01825
gene id: 698758:AXY_RS01825
uniprot id: K0IVN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

698758:AXY RS09910
gene id: 698758:AXY_RS09910
uniprot id: K0IZU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

698758:AXY RS09205
gene id: 698758:AXY_RS09205
uniprot id: K0IZG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

698758:AXY RS04045
gene id: 698758:AXY_RS04045
uniprot id: K0IWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS04975
gene id: 698758:AXY_RS04975
uniprot id: K0J750
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

698758:AXY RS07615
gene id: 698758:AXY_RS07615
uniprot id: K0J3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

698758:AXY RS12090
gene id: 698758:AXY_RS12090
uniprot id: K0J857
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

698758:AXY RS00685
gene id: 698758:AXY_RS00685
uniprot id: K0IV21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

698758:AXY RS02025
gene id: 698758:AXY_RS02025
uniprot id: K0J204
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

698758:AXY RS07595
gene id: 698758:AXY_RS07595
uniprot id: K0J7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

698758:AXY RS05515
gene id: 698758:AXY_RS05515
uniprot id: K0J3Q3
names: Similarity
messages: Belongs to the UPF0297 family.

698758:AXY RS04355
gene id: 698758:AXY_RS04355
uniprot id: K0J1G7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

698758:AXY RS01720
gene id: 698758:AXY_RS01720
uniprot id: K0J612
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS05530
gene id: 698758:AXY_RS05530
uniprot id: K0IXS7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

698758:AXY RS08860
gene id: 698758:AXY_RS08860
uniprot id: K0IZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS04530
gene id: 698758:AXY_RS04530
uniprot id: K0IX87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

698758:AXY RS01540
gene id: 698758:AXY_RS01540
uniprot id: K0IZM4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

698758:AXY RS09865
gene id: 698758:AXY_RS09865
uniprot id: K0J5A1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06190
gene id: 698758:AXY_RS06190
uniprot id: K0J2F3
names: Similarity
messages: Belongs to the Fur family.

698758:AXY RS01665
gene id: 698758:AXY_RS01665
uniprot id: K0IZQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

698758:AXY RS02860
gene id: 698758:AXY_RS02860
uniprot id: K0IW57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS09660
gene id: 698758:AXY_RS09660
uniprot id: K0J569
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS02345
gene id: 698758:AXY_RS02345
uniprot id: K0J261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

698758:AXY RS02075
gene id: 698758:AXY_RS02075
uniprot id: K0IZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS07200
gene id: 698758:AXY_RS07200
uniprot id: K0J7K7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

698758:AXY RS10720
gene id: 698758:AXY_RS10720
uniprot id: K0J5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS00710
gene id: 698758:AXY_RS00710
uniprot id: K0IV26
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

698758:AXY RS04400
gene id: 698758:AXY_RS04400
uniprot id: K0J310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

698758:AXY RS06845
gene id: 698758:AXY_RS06845
uniprot id: K0IY83
names: Similarity
messages: Belongs to the UPF0178 family.

698758:AXY RS06495
gene id: 698758:AXY_RS06495
uniprot id: K0J7G8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

698758:AXY RS01395
gene id: 698758:AXY_RS01395
uniprot id: K0J5X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

698758:AXY RS09090
gene id: 698758:AXY_RS09090
uniprot id: K0J4Z9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

698758:AXY RS07830
gene id: 698758:AXY_RS07830
uniprot id: K0IYR5
names: Similarity
messages: Belongs to the fabD family.

698758:AXY RS10440
gene id: 698758:AXY_RS10440
uniprot id: K0J039
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS10510
gene id: 698758:AXY_RS10510
uniprot id: K0J080
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

698758:AXY RS00135
gene id: 698758:AXY_RS00135
uniprot id: K0J5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS00105
gene id: 698758:AXY_RS00105
uniprot id: K0IYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

698758:AXY RS09330
gene id: 698758:AXY_RS09330
uniprot id: K0IZJ0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

698758:AXY RS06485
gene id: 698758:AXY_RS06485
uniprot id: K0J439
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS04115
gene id: 698758:AXY_RS04115
uniprot id: K0IX03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

698758:AXY RS11170
gene id: 698758:AXY_RS11170
uniprot id: K0J4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

698758:AXY RS04110
gene id: 698758:AXY_RS04110
uniprot id: K0J6W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

698758:AXY RS08595
gene id: 698758:AXY_RS08595
uniprot id: K0IZA6
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS05410
gene id: 698758:AXY_RS05410
uniprot id: K0IXQ8
names: Similarity
messages: Belongs to the RecJ family.

698758:AXY RS04205
gene id: 698758:AXY_RS04205
uniprot id: K0J1D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

698758:AXY RS02155
gene id: 698758:AXY_RS02155
uniprot id: K0J665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS06900
gene id: 698758:AXY_RS06900
uniprot id: K0J4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

698758:AXY RS02985
gene id: 698758:AXY_RS02985
uniprot id: K0J2H3
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

698758:AXY RS00275
gene id: 698758:AXY_RS00275
uniprot id: K0IYX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

698758:AXY RS05365
gene id: 698758:AXY_RS05365
uniprot id: K0IXJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

698758:AXY RS11275
gene id: 698758:AXY_RS11275
uniprot id: K0J0N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

698758:AXY RS04480
gene id: 698758:AXY_RS04480
uniprot id: K0J1I8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS01430
gene id: 698758:AXY_RS01430
uniprot id: K0IVF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS06080
gene id: 698758:AXY_RS06080
uniprot id: K0IY11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

698758:AXY RS10940
gene id: 698758:AXY_RS10940
uniprot id: K0J0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

698758:AXY RS03105
gene id: 698758:AXY_RS03105
uniprot id: K0J2I7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.

698758:AXY RS08480
gene id: 698758:AXY_RS08480
uniprot id: K0IZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

698758:AXY RS12095
gene id: 698758:AXY_RS12095
uniprot id: K0J193
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS08605
gene id: 698758:AXY_RS08605
uniprot id: K0J4U6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07345
gene id: 698758:AXY_RS07345
uniprot id: K0J363
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

698758:AXY RS11560
gene id: 698758:AXY_RS11560
uniprot id: K0J4X2
names: Similarity
messages: Belongs to the peptidase M20A family.

698758:AXY RS10870
gene id: 698758:AXY_RS10870
uniprot id: K0J5L7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

698758:AXY RS09985
gene id: 698758:AXY_RS09985
uniprot id: K0J5D0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

698758:AXY RS08505
gene id: 698758:AXY_RS08505
uniprot id: K0J4T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS10505
gene id: 698758:AXY_RS10505
uniprot id: K0J7Z1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

698758:AXY RS01500
gene id: 698758:AXY_RS01500
uniprot id: K0IVD6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

698758:AXY RS10735
gene id: 698758:AXY_RS10735
uniprot id: K0J0B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

698758:AXY RS10280
gene id: 698758:AXY_RS10280
uniprot id: K0J036
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

698758:AXY RS06060
gene id: 698758:AXY_RS06060
uniprot id: K0IXT4
names: Similarity
messages: Belongs to the asp23 family.

698758:AXY RS08280
gene id: 698758:AXY_RS08280
uniprot id: K0IYY3
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

698758:AXY RS03590
gene id: 698758:AXY_RS03590
uniprot id: K0IWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

698758:AXY RS07025
gene id: 698758:AXY_RS07025
uniprot id: K0J4B3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

698758:AXY RS07880
gene id: 698758:AXY_RS07880
uniprot id: K0IYZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

698758:AXY RS05540
gene id: 698758:AXY_RS05540
uniprot id: K0J3Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

698758:AXY RS10960
gene id: 698758:AXY_RS10960
uniprot id: K0J0H5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

698758:AXY RS00750
gene id: 698758:AXY_RS00750
uniprot id: K0IZ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

698758:AXY RS06415
gene id: 698758:AXY_RS06415
uniprot id: K0J427
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06930
gene id: 698758:AXY_RS06930
uniprot id: K0J2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

698758:AXY RS01870
gene id: 698758:AXY_RS01870
uniprot id: K0IVK5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

698758:AXY RS09410
gene id: 698758:AXY_RS09410
uniprot id: K0IZP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

698758:AXY RS05735
gene id: 698758:AXY_RS05735
uniprot id: K0J3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

698758:AXY RS03680
gene id: 698758:AXY_RS03680
uniprot id: K0J0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

698758:AXY RS09480
gene id: 698758:AXY_RS09480
uniprot id: K0J7U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09315
gene id: 698758:AXY_RS09315
uniprot id: K0J437
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

698758:AXY RS04535
gene id: 698758:AXY_RS04535
uniprot id: K0IX34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

698758:AXY RS06795
gene id: 698758:AXY_RS06795
uniprot id: K0IY72
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

698758:AXY RS06530
gene id: 698758:AXY_RS06530
uniprot id: K0IY20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

698758:AXY RS06340
gene id: 698758:AXY_RS06340
uniprot id: K0J416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

698758:AXY RS00700
gene id: 698758:AXY_RS00700
uniprot id: K0IZ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

698758:AXY RS04730
gene id: 698758:AXY_RS04730
uniprot id: K0IXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

698758:AXY RS06800
gene id: 698758:AXY_RS06800
uniprot id: K0J486
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

698758:AXY RS05340
gene id: 698758:AXY_RS05340
uniprot id: K0IXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

698758:AXY RS09900
gene id: 698758:AXY_RS09900
uniprot id: K0J7W7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

698758:AXY RS01480
gene id: 698758:AXY_RS01480
uniprot id: K0IVF9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

698758:AXY RS09155
gene id: 698758:AXY_RS09155
uniprot id: K0IZF5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

698758:AXY RS06785
gene id: 698758:AXY_RS06785
uniprot id: K0J7I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

698758:AXY RS09925
gene id: 698758:AXY_RS09925
uniprot id: K0J7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS00815
gene id: 698758:AXY_RS00815
uniprot id: K0IV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

698758:AXY RS02755
gene id: 698758:AXY_RS02755
uniprot id: K0IWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

698758:AXY RS00730
gene id: 698758:AXY_RS00730
uniprot id: K0J5P6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

698758:AXY RS09280
gene id: 698758:AXY_RS09280
uniprot id: K0IZH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

698758:AXY RS03605
gene id: 698758:AXY_RS03605
uniprot id: K0J0X7
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08805
gene id: 698758:AXY_RS08805
uniprot id: K0J7S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

698758:AXY RS06990
gene id: 698758:AXY_RS06990
uniprot id: K0IYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS04940
gene id: 698758:AXY_RS04940
uniprot id: K0J3C4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

698758:AXY RS01455
gene id: 698758:AXY_RS01455
uniprot id: K0IVF6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07035
gene id: 698758:AXY_RS07035
uniprot id: K0J7K0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

698758:AXY RS06905
gene id: 698758:AXY_RS06905
uniprot id: K0J2W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

698758:AXY RS06650
gene id: 698758:AXY_RS06650
uniprot id: K0IY43
names: Similarity
messages: Belongs to the acylphosphatase family.

698758:AXY RS00905
gene id: 698758:AXY_RS00905
uniprot id: K0IV55
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS04025
gene id: 698758:AXY_RS04025
uniprot id: K0J2V4
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS04690
gene id: 698758:AXY_RS04690
uniprot id: K0J1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

698758:AXY RS06200
gene id: 698758:AXY_RS06200
uniprot id: K0J7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

698758:AXY RS10945
gene id: 698758:AXY_RS10945
uniprot id: K0J5M5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

698758:AXY RS06235
gene id: 698758:AXY_RS06235
uniprot id: K0IXW7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

698758:AXY RS05865
gene id: 698758:AXY_RS05865
uniprot id: K0J3U6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

698758:AXY RS09885
gene id: 698758:AXY_RS09885
uniprot id: K0IZU4
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS07735
gene id: 698758:AXY_RS07735
uniprot id: K0J4J7
names: Similarity
messages: Belongs to the DprA/Smf family.

698758:AXY RS08335
gene id: 698758:AXY_RS08335
uniprot id: K0J4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

698758:AXY RS08935
gene id: 698758:AXY_RS08935
uniprot id: K0IZG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS10445
gene id: 698758:AXY_RS10445
uniprot id: K0J5H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09655
gene id: 698758:AXY_RS09655
uniprot id: K0IZQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05415
gene id: 698758:AXY_RS05415
uniprot id: K0IXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS01410
gene id: 698758:AXY_RS01410
uniprot id: K0J1N6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

698758:AXY RS05355
gene id: 698758:AXY_RS05355
uniprot id: K0J786
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

698758:AXY RS09435
gene id: 698758:AXY_RS09435
uniprot id: K0IZQ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

698758:AXY RS00680
gene id: 698758:AXY_RS00680
uniprot id: K0J5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

698758:AXY RS06500
gene id: 698758:AXY_RS06500
uniprot id: K0IY81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

698758:AXY RS05085
gene id: 698758:AXY_RS05085
uniprot id: K0IXF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

698758:AXY RS07695
gene id: 698758:AXY_RS07695
uniprot id: K0J7M7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

698758:AXY RS09855
gene id: 698758:AXY_RS09855
uniprot id: K0IZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

698758:AXY RS06585
gene id: 698758:AXY_RS06585
uniprot id: K0J2P5
names: Subcellular Location Annotation
messages: Cytoplasm

698758:AXY RS02880
gene id: 698758:AXY_RS02880
uniprot id: K0IWH2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

698758:AXY RS00810
gene id: 698758:AXY_RS00810
uniprot id: K0IV39
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

698758:AXY RS06215
gene id: 698758:AXY_RS06215
uniprot id: K0J3Z8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

698758:AXY RS04200
gene id: 698758:AXY_RS04200
uniprot id: K0J2X8
names: Similarity
messages: Belongs to the ArsC family.

698758:AXY RS06090
gene id: 698758:AXY_RS06090
uniprot id: K0J3Y0
names: Similarity
messages: Belongs to the TlyA family.

698758:AXY RS04160
gene id: 698758:AXY_RS04160
uniprot id: K0J6W6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

698758:AXY RS01575
gene id: 698758:AXY_RS01575
uniprot id: K0IVE6
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS02900
gene id: 698758:AXY_RS02900
uniprot id: K0J6I6
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

698758:AXY RS00560
gene id: 698758:AXY_RS00560
uniprot id: K0J5M7
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

698758:AXY RS07470
gene id: 698758:AXY_RS07470
uniprot id: K0J7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

698758:AXY RS08025
gene id: 698758:AXY_RS08025
uniprot id: K0IZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

698758:AXY RS08555
gene id: 698758:AXY_RS08555
uniprot id: K0J4U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

698758:AXY RS10540
gene id: 698758:AXY_RS10540
uniprot id: K0J054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

698758:AXY RS10835
gene id: 698758:AXY_RS10835
uniprot id: K0J0D2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS09505
gene id: 698758:AXY_RS09505
uniprot id: K0J7V0
names: Similarity
messages: Belongs to the PspA/IM30 family.

698758:AXY RS02820
gene id: 698758:AXY_RS02820
uniprot id: K0J0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

698758:AXY RS07700
gene id: 698758:AXY_RS07700
uniprot id: K0IYW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

698758:AXY RS10400
gene id: 698758:AXY_RS10400
uniprot id: K0J4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

698758:AXY RS03160
gene id: 698758:AXY_RS03160
uniprot id: K0J0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

698758:AXY RS05950
gene id: 698758:AXY_RS05950
uniprot id: K0J7C7
names: Similarity
messages: Belongs to the GSP E family.

698758:AXY RS08185
gene id: 698758:AXY_RS08185
uniprot id: K0J4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

698758:AXY RS08035
gene id: 698758:AXY_RS08035
uniprot id: K0J4N1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

698758:AXY RS04435
gene id: 698758:AXY_RS04435
uniprot id: K0J6Z2
names: Similarity
messages: Belongs to the asparagine synthetase family.

698758:AXY RS07040
gene id: 698758:AXY_RS07040
uniprot id: K0IYI0
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS02305
gene id: 698758:AXY_RS02305
uniprot id: K0J688
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

698758:AXY RS07960
gene id: 698758:AXY_RS07960
uniprot id: K0J4M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

698758:AXY RS03710
gene id: 698758:AXY_RS03710
uniprot id: K0J6R6
names: Similarity
messages: Belongs to the HPr family.

698758:AXY RS02195
gene id: 698758:AXY_RS02195
uniprot id: K0J235
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

698758:AXY RS04585
gene id: 698758:AXY_RS04585
uniprot id: K0J342
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

698758:AXY RS02140
gene id: 698758:AXY_RS02140
uniprot id: K0IVS3
names: Caution
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS06760
gene id: 698758:AXY_RS06760
uniprot id: K0J7I5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

698758:AXY RS05335
gene id: 698758:AXY_RS05335
uniprot id: K0IXP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

698758:AXY RS06295
gene id: 698758:AXY_RS06295
uniprot id: K0J2H9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

698758:AXY RS02230
gene id: 698758:AXY_RS02230
uniprot id: K0J677
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS05520
gene id: 698758:AXY_RS05520
uniprot id: K0J251
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

698758:AXY RS04880
gene id: 698758:AXY_RS04880
uniprot id: K0IXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

698758:AXY RS11990
gene id: 698758:AXY_RS11990
uniprot id: K0J853
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

698758:AXY RS06890
gene id: 698758:AXY_RS06890
uniprot id: K0IYF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

698758:AXY RS00030
gene id: 698758:AXY_RS00030
uniprot id: K0J5I2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

698758:AXY RS03130
gene id: 698758:AXY_RS03130
uniprot id: K0J2I9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

698758:AXY RS07080
gene id: 698758:AXY_RS07080
uniprot id: K0J2Z7
names: Similarity
messages: Belongs to the YjdM family.

698758:AXY RS00765
gene id: 698758:AXY_RS00765
uniprot id: K0IV90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

698758:AXY RS02865
gene id: 698758:AXY_RS02865
uniprot id: K0J2F7
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS09080
gene id: 698758:AXY_RS09080
uniprot id: K0IZJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

698758:AXY RS01630
gene id: 698758:AXY_RS01630
uniprot id: K0IVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

698758:AXY RS07295
gene id: 698758:AXY_RS07295
uniprot id: K0J352
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

698758:AXY RS09380
gene id: 698758:AXY_RS09380
uniprot id: K0J7U5
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

698758:AXY RS04685
gene id: 698758:AXY_RS04685
uniprot id: K0J365
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

698758:AXY RS09475
gene id: 698758:AXY_RS09475
uniprot id: K0J460
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

698758:AXY RS00020
gene id: 698758:AXY_RS00020
uniprot id: K0J112
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

698758:AXY RS11130
gene id: 698758:AXY_RS11130
uniprot id: K0J816
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

698758:AXY RS07900
gene id: 698758:AXY_RS07900
uniprot id: K0J7N5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

698758:AXY RS03140
gene id: 698758:AXY_RS03140
uniprot id: K0J6K9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

698758:AXY RS10605
gene id: 698758:AXY_RS10605
uniprot id: K0J7Z5
names: Subcellular Location Annotation
messages: Cell membrane

698758:AXY RS00425
gene id: 698758:AXY_RS00425
uniprot id: K0J159
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

698758:AXY RS01590
gene id: 698758:AXY_RS01590
uniprot id: K0IZN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

698758:AXY RS04365
gene id: 698758:AXY_RS04365
uniprot id: K0IX62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

698758:AXY RS06140
gene id: 698758:AXY_RS06140
uniprot id: K0J3Y6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

698758:AXY RS11920
gene id: 698758:AXY_RS11920
uniprot id: K0J135
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS08430
gene id: 698758:AXY_RS08430
uniprot id: K0IZ08
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

698758:AXY RS05575
gene id: 698758:AXY_RS05575
uniprot id: K0IXT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS11805
gene id: 698758:AXY_RS11805
uniprot id: K0J845
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

698758:AXY RS03665
gene id: 698758:AXY_RS03665
uniprot id: K0IWS1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

698758:AXY RS05250
gene id: 698758:AXY_RS05250
uniprot id: K0J215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

698758:AXY RS10190
gene id: 698758:AXY_RS10190
uniprot id: K0J5F1
names: Subcellular Location Annotation
messages: Membrane

698758:AXY RS08690
gene id: 698758:AXY_RS08690
uniprot id: K0IZC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

698758:AXY RS08095
gene id: 698758:AXY_RS08095
uniprot id: K0J7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

698758:AXY RS05475
gene id: 698758:AXY_RS05475
uniprot id: K0J245
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

698758:AXY RS05310
gene id: 698758:AXY_RS05310
uniprot id: K0IXP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

698758:AXY RS08050
gene id: 698758:AXY_RS08050
uniprot id: K0IZ22
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

698758:AXY RS07725
gene id: 698758:AXY_RS07725
uniprot id: K0IYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

698758:AXY RS08080
gene id: 698758:AXY_RS08080
uniprot id: K0IYU9
names: Similarity
messages: Belongs to the UPF0749 family.

698758:AXY RS09405
gene id: 698758:AXY_RS09405
uniprot id: K0J7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

698758:AXY RS11995
gene id: 698758:AXY_RS11995
uniprot id: K0J161
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

698758:AXY RS04910
gene id: 698758:AXY_RS04910
uniprot id: K0IX96
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.