696281:DESRU RS08245
gene id: 696281:DESRU_RS08245
uniprot id: F6DSA6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

696281:DESRU RS00570
gene id: 696281:DESRU_RS00570
uniprot id: F6DLW5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS06545
gene id: 696281:DESRU_RS06545
uniprot id: F6DNW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

696281:DESRU RS03745
gene id: 696281:DESRU_RS03745
uniprot id: F6DU01
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

696281:DESRU RS13710
gene id: 696281:DESRU_RS13710
uniprot id: F6DR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

696281:DESRU RS05210
gene id: 696281:DESRU_RS05210
uniprot id: F6DL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

696281:DESRU RS04985
gene id: 696281:DESRU_RS04985
uniprot id: F6DKJ4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

696281:DESRU RS11685
gene id: 696281:DESRU_RS11685
uniprot id: F6DM92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

696281:DESRU RS02560
gene id: 696281:DESRU_RS02560
uniprot id: F6DS28
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS09865
gene id: 696281:DESRU_RS09865
uniprot id: F6DUR0
names: Similarity
messages: Belongs to the CinA family.

696281:DESRU RS08175
gene id: 696281:DESRU_RS08175
uniprot id: F6DS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

696281:DESRU RS15765
gene id: 696281:DESRU_RS15765
uniprot id: F6DUE5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS04880
gene id: 696281:DESRU_RS04880
uniprot id: F6DKH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

696281:DESRU RS12080
gene id: 696281:DESRU_RS12080
uniprot id: F6DN44
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

696281:DESRU RS09690
gene id: 696281:DESRU_RS09690
uniprot id: F6DUM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

696281:DESRU RS11990
gene id: 696281:DESRU_RS11990
uniprot id: F6DN26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

696281:DESRU RS13185
gene id: 696281:DESRU_RS13185
uniprot id: F6DPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

696281:DESRU RS18575
gene id: 696281:DESRU_RS18575
uniprot id: F6DP59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

696281:DESRU RS04435
gene id: 696281:DESRU_RS04435
uniprot id: F6DV80
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS16830
gene id: 696281:DESRU_RS16830
uniprot id: F6DKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

696281:DESRU RS00735
gene id: 696281:DESRU_RS00735
uniprot id: F6DMN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

696281:DESRU RS17425
gene id: 696281:DESRU_RS17425
uniprot id: F6DLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

696281:DESRU RS09155
gene id: 696281:DESRU_RS09155
uniprot id: F6DTJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

696281:DESRU RS19620
gene id: 696281:DESRU_RS19620
uniprot id: F6DRF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS05145
gene id: 696281:DESRU_RS05145
uniprot id: F6DL63
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

696281:DESRU RS17475
gene id: 696281:DESRU_RS17475
uniprot id: F6DLM2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

696281:DESRU RS13675
gene id: 696281:DESRU_RS13675
uniprot id: F6DR93
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

696281:DESRU RS08685
gene id: 696281:DESRU_RS08685
uniprot id: F6DSX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

696281:DESRU RS04650
gene id: 696281:DESRU_RS04650
uniprot id: F6DJX4
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

696281:DESRU RS01115
gene id: 696281:DESRU_RS01115
uniprot id: F6DNH7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

696281:DESRU RS09375
gene id: 696281:DESRU_RS09375
uniprot id: F6DU31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

696281:DESRU RS07860
gene id: 696281:DESRU_RS07860
uniprot id: F6DRP8
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS16080
gene id: 696281:DESRU_RS16080
uniprot id: F6DUZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

696281:DESRU RS19480
gene id: 696281:DESRU_RS19480
uniprot id: F6DQS5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

696281:DESRU RS09640
gene id: 696281:DESRU_RS09640
uniprot id: F6DU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

696281:DESRU RS00205
gene id: 696281:DESRU_RS00205
uniprot id: F6DL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18600
gene id: 696281:DESRU_RS18600
uniprot id: F6DP64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

696281:DESRU RS06360
gene id: 696281:DESRU_RS06360
uniprot id: F6DNS2
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

696281:DESRU RS19615
gene id: 696281:DESRU_RS19615
uniprot id: F6DRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

696281:DESRU RS18730
gene id: 696281:DESRU_RS18730
uniprot id: F6DP89
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06410
gene id: 696281:DESRU_RS06410
uniprot id: F6DNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

696281:DESRU RS12605
gene id: 696281:DESRU_RS12605
uniprot id: F6DNZ8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

696281:DESRU RS17110
gene id: 696281:DESRU_RS17110
uniprot id: F6DKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18660
gene id: 696281:DESRU_RS18660
uniprot id: F6DP76
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

696281:DESRU RS13020
gene id: 696281:DESRU_RS13020
uniprot id: F6DPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS03990
gene id: 696281:DESRU_RS03990
uniprot id: F6DUJ6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

696281:DESRU RS15735
gene id: 696281:DESRU_RS15735
uniprot id: F6DUD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

696281:DESRU RS06055
gene id: 696281:DESRU_RS06055
uniprot id: F6DN02
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

696281:DESRU RS10705
gene id: 696281:DESRU_RS10705
uniprot id: F6DK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS07125
gene id: 696281:DESRU_RS07125
uniprot id: F6DQ92
names: Similarity
messages: Belongs to the catalase family.

696281:DESRU RS01220
gene id: 696281:DESRU_RS01220
uniprot id: F6DNJ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

696281:DESRU RS06565
gene id: 696281:DESRU_RS06565
uniprot id: F6DNW4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

696281:DESRU RS07275
gene id: 696281:DESRU_RS07275
uniprot id: F6DQB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS06290
gene id: 696281:DESRU_RS06290
uniprot id: F6DNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

696281:DESRU RS05765
gene id: 696281:DESRU_RS05765
uniprot id: F6DM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

696281:DESRU RS13750
gene id: 696281:DESRU_RS13750
uniprot id: F6DRA7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS15180
gene id: 696281:DESRU_RS15180
uniprot id: F6DTP0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

696281:DESRU RS00330
gene id: 696281:DESRU_RS00330
uniprot id: F6DLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

696281:DESRU RS19920
gene id: 696281:DESRU_RS19920
uniprot id: F6DPT7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS06030
gene id: 696281:DESRU_RS06030
uniprot id: F6DMZ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS01695
gene id: 696281:DESRU_RS01695
uniprot id: F6DPE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

696281:DESRU RS18205
gene id: 696281:DESRU_RS18205
uniprot id: F6DNC4
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS08480
gene id: 696281:DESRU_RS08480
uniprot id: F6DSE9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

696281:DESRU RS15725
gene id: 696281:DESRU_RS15725
uniprot id: F6DUD7
names: Similarity
messages: Belongs to the GSP E family.

696281:DESRU RS12510
gene id: 696281:DESRU_RS12510
uniprot id: F6DNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

696281:DESRU RS17025
gene id: 696281:DESRU_RS17025
uniprot id: F6DKV0
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

696281:DESRU RS09660
gene id: 696281:DESRU_RS09660
uniprot id: F6DUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

696281:DESRU RS02375
gene id: 696281:DESRU_RS02375
uniprot id: F6DRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

696281:DESRU RS01010
gene id: 696281:DESRU_RS01010
uniprot id: F6DMT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

696281:DESRU RS18970
gene id: 696281:DESRU_RS18970
uniprot id: F6DQ24
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS02275
gene id: 696281:DESRU_RS02275
uniprot id: F6DRH9
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS06590
gene id: 696281:DESRU_RS06590
uniprot id: F6DPI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

696281:DESRU RS05790
gene id: 696281:DESRU_RS05790
uniprot id: F6DMV4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

696281:DESRU RS00415
gene id: 696281:DESRU_RS00415
uniprot id: F6DLT5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

696281:DESRU RS03015
gene id: 696281:DESRU_RS03015
uniprot id: F6DSR1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

696281:DESRU RS10170
gene id: 696281:DESRU_RS10170
uniprot id: F6DVA7
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

696281:DESRU RS13320
gene id: 696281:DESRU_RS13320
uniprot id: F6DQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS09755
gene id: 696281:DESRU_RS09755
uniprot id: F6DUP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

696281:DESRU RS08530
gene id: 696281:DESRU_RS08530
uniprot id: F6DSU2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

696281:DESRU RS12210
gene id: 696281:DESRU_RS12210
uniprot id: F6DN69
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

696281:DESRU RS11165
gene id: 696281:DESRU_RS11165
uniprot id: F6DKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS11630
gene id: 696281:DESRU_RS11630
uniprot id: F6DM81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

696281:DESRU RS16705
gene id: 696281:DESRU_RS16705
uniprot id: F6DKA1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS12515
gene id: 696281:DESRU_RS12515
uniprot id: F6DNY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

696281:DESRU RS15245
gene id: 696281:DESRU_RS15245
uniprot id: F6DTQ2
names: Similarity
messages: Belongs to the GerABKA family.

696281:DESRU RS08220
gene id: 696281:DESRU_RS08220
uniprot id: F6DSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

696281:DESRU RS11690
gene id: 696281:DESRU_RS11690
uniprot id: F6DM93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

696281:DESRU RS06450
gene id: 696281:DESRU_RS06450
uniprot id: F6DNU0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

696281:DESRU RS07610
gene id: 696281:DESRU_RS07610
uniprot id: F6DR41
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

696281:DESRU RS02645
gene id: 696281:DESRU_RS02645
uniprot id: F6DS45
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

696281:DESRU RS01930
gene id: 696281:DESRU_RS01930
uniprot id: F6DQU3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS06230
gene id: 696281:DESRU_RS06230
uniprot id: F6DNP7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

696281:DESRU RS02190
gene id: 696281:DESRU_RS02190
uniprot id: F6DQZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS08860
gene id: 696281:DESRU_RS08860
uniprot id: F6DT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

696281:DESRU RS03785
gene id: 696281:DESRU_RS03785
uniprot id: F6DUF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

696281:DESRU RS01830
gene id: 696281:DESRU_RS01830
uniprot id: F6DPH5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS03835
gene id: 696281:DESRU_RS03835
uniprot id: F6DUG9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

696281:DESRU RS18275
gene id: 696281:DESRU_RS18275
uniprot id: F6DND8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS12105
gene id: 696281:DESRU_RS12105
uniprot id: F6DN48
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

696281:DESRU RS15660
gene id: 696281:DESRU_RS15660
uniprot id: F6DUC4
names: Similarity
messages: Belongs to the peptidase U62 family.

696281:DESRU RS18055
gene id: 696281:DESRU_RS18055
uniprot id: F6DMM5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

696281:DESRU RS05020
gene id: 696281:DESRU_RS05020
uniprot id: F6DKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

696281:DESRU RS02545
gene id: 696281:DESRU_RS02545
uniprot id: F6DS25
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS12845
gene id: 696281:DESRU_RS12845
uniprot id: F6DPS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS00635
gene id: 696281:DESRU_RS00635
uniprot id: F6DLX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS01225
gene id: 696281:DESRU_RS01225
uniprot id: F6DNJ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

696281:DESRU RS12520
gene id: 696281:DESRU_RS12520
uniprot id: F6DNY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

696281:DESRU RS02360
gene id: 696281:DESRU_RS02360
uniprot id: F6DRJ6
names: Similarity
messages: Belongs to the GSP E family.

696281:DESRU RS02280
gene id: 696281:DESRU_RS02280
uniprot id: F6DRI0
names: Similarity
messages: Belongs to the glutamine synthetase family.

696281:DESRU RS15215
gene id: 696281:DESRU_RS15215
uniprot id: F6DTP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

696281:DESRU RS00200
gene id: 696281:DESRU_RS00200
uniprot id: F6DL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS13960
gene id: 696281:DESRU_RS13960
uniprot id: F6DRV6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS05425
gene id: 696281:DESRU_RS05425
uniprot id: F6DLZ6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS18150
gene id: 696281:DESRU_RS18150
uniprot id: F6DNB3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

696281:DESRU RS06595
gene id: 696281:DESRU_RS06595
uniprot id: F6DPI8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

696281:DESRU RS18435
gene id: 696281:DESRU_RS18435
uniprot id: F6DNH0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

696281:DESRU RS06935
gene id: 696281:DESRU_RS06935
uniprot id: F6DPQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS15525
gene id: 696281:DESRU_RS15525
uniprot id: F6DU97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

696281:DESRU RS01335
gene id: 696281:DESRU_RS01335
uniprot id: F6DNL3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

696281:DESRU RS15895
gene id: 696281:DESRU_RS15895
uniprot id: F6DUW0
names: Similarity
messages: Belongs to the thioredoxin family.

696281:DESRU RS07210
gene id: 696281:DESRU_RS07210
uniprot id: F6DQA8
names: Similarity
messages: Belongs to the universal stress protein A family.

696281:DESRU RS06615
gene id: 696281:DESRU_RS06615
uniprot id: F6DPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

696281:DESRU RS02520
gene id: 696281:DESRU_RS02520
uniprot id: F6DS20
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS12110
gene id: 696281:DESRU_RS12110
uniprot id: F6DN49
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

696281:DESRU RS14710
gene id: 696281:DESRU_RS14710
uniprot id: F6DT15
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

696281:DESRU RS01110
gene id: 696281:DESRU_RS01110
uniprot id: F6DNH6
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

696281:DESRU RS01365
gene id: 696281:DESRU_RS01365
uniprot id: F6DNL9
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

696281:DESRU RS13260
gene id: 696281:DESRU_RS13260
uniprot id: F6DQF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS05120
gene id: 696281:DESRU_RS05120
uniprot id: F6DL58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

696281:DESRU RS01410
gene id: 696281:DESRU_RS01410
uniprot id: F6DNM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS05710
gene id: 696281:DESRU_RS05710
uniprot id: F6DM54
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

696281:DESRU RS15575
gene id: 696281:DESRU_RS15575
uniprot id: F6DUA7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

696281:DESRU RS18715
gene id: 696281:DESRU_RS18715
uniprot id: F6DP86
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS07110
gene id: 696281:DESRU_RS07110
uniprot id: F6DQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18840
gene id: 696281:DESRU_RS18840
uniprot id: F6DPZ7
names: Similarity
messages: Belongs to the peptidase M29 family.

696281:DESRU RS08795
gene id: 696281:DESRU_RS08795
uniprot id: F6DSZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

696281:DESRU RS01260
gene id: 696281:DESRU_RS01260
uniprot id: F6DNK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

696281:DESRU RS10490
gene id: 696281:DESRU_RS10490
uniprot id: F6DK12
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

696281:DESRU RS05775
gene id: 696281:DESRU_RS05775
uniprot id: F6DM67
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

696281:DESRU RS19060
gene id: 696281:DESRU_RS19060
uniprot id: F6DQ43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS18340
gene id: 696281:DESRU_RS18340
uniprot id: F6DNF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

696281:DESRU RS10845
gene id: 696281:DESRU_RS10845
uniprot id: F6DKL7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

696281:DESRU RS06495
gene id: 696281:DESRU_RS06495
uniprot id: F6DNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

696281:DESRU RS09850
gene id: 696281:DESRU_RS09850
uniprot id: F6DUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

696281:DESRU RS15790
gene id: 696281:DESRU_RS15790
uniprot id: F6DUF0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS18545
gene id: 696281:DESRU_RS18545
uniprot id: F6DP53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS18620
gene id: 696281:DESRU_RS18620
uniprot id: F6DP68
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

696281:DESRU RS13060
gene id: 696281:DESRU_RS13060
uniprot id: F6DPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS01625
gene id: 696281:DESRU_RS01625
uniprot id: F6DPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS05140
gene id: 696281:DESRU_RS05140
uniprot id: F6DL62
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

696281:DESRU RS05795
gene id: 696281:DESRU_RS05795
uniprot id: F6DMV5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

696281:DESRU RS18290
gene id: 696281:DESRU_RS18290
uniprot id: F6DNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

696281:DESRU RS09655
gene id: 696281:DESRU_RS09655
uniprot id: F6DUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

696281:DESRU RS11960
gene id: 696281:DESRU_RS11960
uniprot id: F6DME2
names: Similarity
messages: Belongs to the HupF/HypC family.

696281:DESRU RS09160
gene id: 696281:DESRU_RS09160
uniprot id: F6DTK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

696281:DESRU RS01645
gene id: 696281:DESRU_RS01645
uniprot id: F6DPD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

696281:DESRU RS14345
gene id: 696281:DESRU_RS14345
uniprot id: F6DSF5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

696281:DESRU RS10840
gene id: 696281:DESRU_RS10840
uniprot id: F6DKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

696281:DESRU RS12050
gene id: 696281:DESRU_RS12050
uniprot id: F6DN38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

696281:DESRU RS01510
gene id: 696281:DESRU_RS01510
uniprot id: F6DPB0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

696281:DESRU RS11315
gene id: 696281:DESRU_RS11315
uniprot id: F6DLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

696281:DESRU RS01640
gene id: 696281:DESRU_RS01640
uniprot id: F6DPD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

696281:DESRU RS10080
gene id: 696281:DESRU_RS10080
uniprot id: F6DV89
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

696281:DESRU RS16340
gene id: 696281:DESRU_RS16340
uniprot id: F6DVI7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

696281:DESRU RS05905
gene id: 696281:DESRU_RS05905
uniprot id: F6DMX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

696281:DESRU RS08095
gene id: 696281:DESRU_RS08095
uniprot id: F6DRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS06200
gene id: 696281:DESRU_RS06200
uniprot id: F6DNP1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

696281:DESRU RS09080
gene id: 696281:DESRU_RS09080
uniprot id: F6DTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

696281:DESRU RS18725
gene id: 696281:DESRU_RS18725
uniprot id: F6DP88
names: Similarity
messages: Belongs to the peptidase S49 family.

696281:DESRU RS06665
gene id: 696281:DESRU_RS06665
uniprot id: F6DPK2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

696281:DESRU RS13510
gene id: 696281:DESRU_RS13510
uniprot id: F6DQK1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

696281:DESRU RS00750
gene id: 696281:DESRU_RS00750
uniprot id: F6DMN5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

696281:DESRU RS19160
gene id: 696281:DESRU_RS19160
uniprot id: F6DQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

696281:DESRU RS15155
gene id: 696281:DESRU_RS15155
uniprot id: F6DTN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

696281:DESRU RS10850
gene id: 696281:DESRU_RS10850
uniprot id: F6DKL8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

696281:DESRU RS13105
gene id: 696281:DESRU_RS13105
uniprot id: F6DPX3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

696281:DESRU RS12695
gene id: 696281:DESRU_RS12695
uniprot id: F6DP14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

696281:DESRU RS14475
gene id: 696281:DESRU_RS14475
uniprot id: F6DSI3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

696281:DESRU RS09195
gene id: 696281:DESRU_RS09195
uniprot id: F6DTK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

696281:DESRU RS13415
gene id: 696281:DESRU_RS13415
uniprot id: F6DQI1
names: Similarity
messages: Belongs to the UPF0178 family.

696281:DESRU RS12225
gene id: 696281:DESRU_RS12225
uniprot id: F6DN72
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

696281:DESRU RS01835
gene id: 696281:DESRU_RS01835
uniprot id: F6DPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

696281:DESRU RS08280
gene id: 696281:DESRU_RS08280
uniprot id: F6DSB3
names: Similarity
messages: Belongs to the Ahb/Nir family.

696281:DESRU RS18515
gene id: 696281:DESRU_RS18515
uniprot id: F6DP47
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06925
gene id: 696281:DESRU_RS06925
uniprot id: F6DPQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

696281:DESRU RS06620
gene id: 696281:DESRU_RS06620
uniprot id: F6DPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

696281:DESRU RS04790
gene id: 696281:DESRU_RS04790
uniprot id: F6DKF5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS13490
gene id: 696281:DESRU_RS13490
uniprot id: F6DQJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS16020
gene id: 696281:DESRU_RS16020
uniprot id: F6DUY7
names: Similarity
messages: Belongs to the thioredoxin family.

696281:DESRU RS16530
gene id: 696281:DESRU_RS16530
uniprot id: F6DVM5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS13870
gene id: 696281:DESRU_RS13870
uniprot id: F6DRD1
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS18690
gene id: 696281:DESRU_RS18690
uniprot id: F6DP81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS00675
gene id: 696281:DESRU_RS00675
uniprot id: F6DLY5
names: Similarity
messages: Belongs to the UPF0045 family.

696281:DESRU RS15825
gene id: 696281:DESRU_RS15825
uniprot id: F6DUF7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

696281:DESRU RS01030
gene id: 696281:DESRU_RS01030
uniprot id: F6DMU2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

696281:DESRU RS11930
gene id: 696281:DESRU_RS11930
uniprot id: F6DMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

696281:DESRU RS10095
gene id: 696281:DESRU_RS10095
uniprot id: F6DV92
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

696281:DESRU RS01185
gene id: 696281:DESRU_RS01185
uniprot id: F6DNJ0
names: Similarity
messages: Belongs to the DHPS family.

696281:DESRU RS15045
gene id: 696281:DESRU_RS15045
uniprot id: F6DT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS01980
gene id: 696281:DESRU_RS01980
uniprot id: F6DQV4
names: Similarity
messages: Belongs to the ComB family.

696281:DESRU RS00565
gene id: 696281:DESRU_RS00565
uniprot id: F6DLW4
names: Similarity
messages: Belongs to the GerABKA family.

696281:DESRU RS15280
gene id: 696281:DESRU_RS15280
uniprot id: F6DTQ9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

696281:DESRU RS06465
gene id: 696281:DESRU_RS06465
uniprot id: F6DNU3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS10975
gene id: 696281:DESRU_RS10975
uniprot id: F6DKP1
names: Similarity
messages: Belongs to the GerABKA family.

696281:DESRU RS12165
gene id: 696281:DESRU_RS12165
uniprot id: F6DN60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

696281:DESRU RS08035
gene id: 696281:DESRU_RS08035
uniprot id: F6DRT3
names: Subcellular Location Annotation
messages: Cytoplasm

696281:DESRU RS07765
gene id: 696281:DESRU_RS07765
uniprot id: F6DRN0
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS10710
gene id: 696281:DESRU_RS10710
uniprot id: F6DK51
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS13295
gene id: 696281:DESRU_RS13295
uniprot id: F6DQF8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

696281:DESRU RS18805
gene id: 696281:DESRU_RS18805
uniprot id: F6DPA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

696281:DESRU RS00515
gene id: 696281:DESRU_RS00515
uniprot id: F6DLV4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

696281:DESRU RS05355
gene id: 696281:DESRU_RS05355
uniprot id: F6DLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS13495
gene id: 696281:DESRU_RS13495
uniprot id: F6DQJ8
names: Similarity
messages: Belongs to the FBPase class 2 family.

696281:DESRU RS10545
gene id: 696281:DESRU_RS10545
uniprot id: F6DK23
names: Similarity
messages: Belongs to the EutP/PduV family.

696281:DESRU RS01535
gene id: 696281:DESRU_RS01535
uniprot id: F6DPB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

696281:DESRU RS15110
gene id: 696281:DESRU_RS15110
uniprot id: F6DTM7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

696281:DESRU RS09400
gene id: 696281:DESRU_RS09400
uniprot id: F6DU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

696281:DESRU RS11795
gene id: 696281:DESRU_RS11795
uniprot id: F6DMB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

696281:DESRU RS14420
gene id: 696281:DESRU_RS14420
uniprot id: F6DSH0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

696281:DESRU RS01765
gene id: 696281:DESRU_RS01765
uniprot id: F6DPG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

696281:DESRU RS11040
gene id: 696281:DESRU_RS11040
uniprot id: F6DKQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

696281:DESRU RS00865
gene id: 696281:DESRU_RS00865
uniprot id: F6DMQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS12555
gene id: 696281:DESRU_RS12555
uniprot id: F6DNY9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01285
gene id: 696281:DESRU_RS01285
uniprot id: F6DNK9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

696281:DESRU RS00680
gene id: 696281:DESRU_RS00680
uniprot id: F6DLY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS15865
gene id: 696281:DESRU_RS15865
uniprot id: F6DUV4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

696281:DESRU RS15350
gene id: 696281:DESRU_RS15350
uniprot id: F6DTS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS03880
gene id: 696281:DESRU_RS03880
uniprot id: F6DUH7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS18350
gene id: 696281:DESRU_RS18350
uniprot id: F6DNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

696281:DESRU RS13575
gene id: 696281:DESRU_RS13575
uniprot id: F6DR73
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

696281:DESRU RS01555
gene id: 696281:DESRU_RS01555
uniprot id: F6DPB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

696281:DESRU RS01635
gene id: 696281:DESRU_RS01635
uniprot id: F6DPD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

696281:DESRU RS10300
gene id: 696281:DESRU_RS10300
uniprot id: F6DVD4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS05770
gene id: 696281:DESRU_RS05770
uniprot id: F6DM66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

696281:DESRU RS14315
gene id: 696281:DESRU_RS14315
uniprot id: F6DS15
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

696281:DESRU RS18565
gene id: 696281:DESRU_RS18565
uniprot id: F6DP57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01585
gene id: 696281:DESRU_RS01585
uniprot id: F6DPC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

696281:DESRU RS05040
gene id: 696281:DESRU_RS05040
uniprot id: F6DKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

696281:DESRU RS16840
gene id: 696281:DESRU_RS16840
uniprot id: F6DKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

696281:DESRU RS19230
gene id: 696281:DESRU_RS19230
uniprot id: F6DQM5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS10505
gene id: 696281:DESRU_RS10505
uniprot id: F6DK15
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

696281:DESRU RS06685
gene id: 696281:DESRU_RS06685
uniprot id: F6DPK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

696281:DESRU RS13560
gene id: 696281:DESRU_RS13560
uniprot id: F6DR70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

696281:DESRU RS12365
gene id: 696281:DESRU_RS12365
uniprot id: F6DN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

696281:DESRU RS06325
gene id: 696281:DESRU_RS06325
uniprot id: F6DNR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

696281:DESRU RS09555
gene id: 696281:DESRU_RS09555
uniprot id: F6DU68
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

696281:DESRU RS02885
gene id: 696281:DESRU_RS02885
uniprot id: F6DSN5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS16710
gene id: 696281:DESRU_RS16710
uniprot id: F6DKA2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

696281:DESRU RS00010
gene id: 696281:DESRU_RS00010
uniprot id: F6DL00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

696281:DESRU RS18720
gene id: 696281:DESRU_RS18720
uniprot id: F6DP87
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS09295
gene id: 696281:DESRU_RS09295
uniprot id: F6DU15
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

696281:DESRU RS03170
gene id: 696281:DESRU_RS03170
uniprot id: F6DT91
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS19550
gene id: 696281:DESRU_RS19550
uniprot id: F6DRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

696281:DESRU RS19170
gene id: 696281:DESRU_RS19170
uniprot id: F6DQL3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

696281:DESRU RS08675
gene id: 696281:DESRU_RS08675
uniprot id: F6DSX2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

696281:DESRU RS02895
gene id: 696281:DESRU_RS02895
uniprot id: F6DSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

696281:DESRU RS17520
gene id: 696281:DESRU_RS17520
uniprot id: F6DLN1
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS03160
gene id: 696281:DESRU_RS03160
uniprot id: F6DST7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS03035
gene id: 696281:DESRU_RS03035
uniprot id: F6DSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

696281:DESRU RS05925
gene id: 696281:DESRU_RS05925
uniprot id: F6DMY1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

696281:DESRU RS08100
gene id: 696281:DESRU_RS08100
uniprot id: F6DRU6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS19405
gene id: 696281:DESRU_RS19405
uniprot id: F6DQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS00585
gene id: 696281:DESRU_RS00585
uniprot id: F6DLW8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

696281:DESRU RS17665
gene id: 696281:DESRU_RS17665
uniprot id: F6DLR3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

696281:DESRU RS02140
gene id: 696281:DESRU_RS02140
uniprot id: F6DQY3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS19425
gene id: 696281:DESRU_RS19425
uniprot id: F6DQR4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

696281:DESRU RS05270
gene id: 696281:DESRU_RS05270
uniprot id: F6DL87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

696281:DESRU RS05050
gene id: 696281:DESRU_RS05050
uniprot id: F6DKK9
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS10670
gene id: 696281:DESRU_RS10670
uniprot id: F6DK43
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS06670
gene id: 696281:DESRU_RS06670
uniprot id: F6DPK3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

696281:DESRU RS01490
gene id: 696281:DESRU_RS01490
uniprot id: F6DPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

696281:DESRU RS14655
gene id: 696281:DESRU_RS14655
uniprot id: F6DSL9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

696281:DESRU RS12040
gene id: 696281:DESRU_RS12040
uniprot id: F6DN36
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

696281:DESRU RS04855
gene id: 696281:DESRU_RS04855
uniprot id: F6DKG8
names: Similarity
messages: Belongs to the UPF0111 family.

696281:DESRU RS03010
gene id: 696281:DESRU_RS03010
uniprot id: F6DSR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

696281:DESRU RS08845
gene id: 696281:DESRU_RS08845
uniprot id: F6DT06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

696281:DESRU RS06715
gene id: 696281:DESRU_RS06715
uniprot id: F6DPL2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

696281:DESRU RS11235
gene id: 696281:DESRU_RS11235
uniprot id: F6DLC1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

696281:DESRU RS00870
gene id: 696281:DESRU_RS00870
uniprot id: F6DMR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

696281:DESRU RS14835
gene id: 696281:DESRU_RS14835
uniprot id: F6DT39
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

696281:DESRU RS06580
gene id: 696281:DESRU_RS06580
uniprot id: F6DPI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

696281:DESRU RS00090
gene id: 696281:DESRU_RS00090
uniprot id: F6DL15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

696281:DESRU RS07975
gene id: 696281:DESRU_RS07975
uniprot id: F6DRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

696281:DESRU RS12680
gene id: 696281:DESRU_RS12680
uniprot id: F6DP11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

696281:DESRU RS16040
gene id: 696281:DESRU_RS16040
uniprot id: F6DUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

696281:DESRU RS09275
gene id: 696281:DESRU_RS09275
uniprot id: F6DU11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS09190
gene id: 696281:DESRU_RS09190
uniprot id: F6DTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS12650
gene id: 696281:DESRU_RS12650
uniprot id: F6DP05
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

696281:DESRU RS07915
gene id: 696281:DESRU_RS07915
uniprot id: F6DRR0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

696281:DESRU RS04820
gene id: 696281:DESRU_RS04820
uniprot id: F6DKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS12160
gene id: 696281:DESRU_RS12160
uniprot id: F6DN59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

696281:DESRU RS15540
gene id: 696281:DESRU_RS15540
uniprot id: F6DUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

696281:DESRU RS06585
gene id: 696281:DESRU_RS06585
uniprot id: F6DPI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

696281:DESRU RS15720
gene id: 696281:DESRU_RS15720
uniprot id: F6DUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS01735
gene id: 696281:DESRU_RS01735
uniprot id: F6DPF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS02650
gene id: 696281:DESRU_RS02650
uniprot id: F6DS46
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

696281:DESRU RS01745
gene id: 696281:DESRU_RS01745
uniprot id: F6DPF7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS04525
gene id: 696281:DESRU_RS04525
uniprot id: F6DJV0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

696281:DESRU RS07875
gene id: 696281:DESRU_RS07875
uniprot id: F6DRQ1
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

696281:DESRU RS10475
gene id: 696281:DESRU_RS10475
uniprot id: F6DK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS16495
gene id: 696281:DESRU_RS16495
uniprot id: F6DVL8
names: Similarity
messages: Belongs to the RecJ family.

696281:DESRU RS11850
gene id: 696281:DESRU_RS11850
uniprot id: F6DMC1
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

696281:DESRU RS01015
gene id: 696281:DESRU_RS01015
uniprot id: F6DMT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

696281:DESRU RS02125
gene id: 696281:DESRU_RS02125
uniprot id: F6DQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS12685
gene id: 696281:DESRU_RS12685
uniprot id: F6DP12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

696281:DESRU RS14455
gene id: 696281:DESRU_RS14455
uniprot id: F6DSH8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

696281:DESRU RS09480
gene id: 696281:DESRU_RS09480
uniprot id: F6DU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

696281:DESRU RS09950
gene id: 696281:DESRU_RS09950
uniprot id: F6DUS7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

696281:DESRU RS01255
gene id: 696281:DESRU_RS01255
uniprot id: F6DNK4
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01880
gene id: 696281:DESRU_RS01880
uniprot id: F6DQT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

696281:DESRU RS14760
gene id: 696281:DESRU_RS14760
uniprot id: F6DT25
names: Similarity
messages: Belongs to the universal stress protein A family.

696281:DESRU RS08550
gene id: 696281:DESRU_RS08550
uniprot id: F6DSU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

696281:DESRU RS05175
gene id: 696281:DESRU_RS05175
uniprot id: F6DL69
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

696281:DESRU RS07810
gene id: 696281:DESRU_RS07810
uniprot id: F6DRN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

696281:DESRU RS11385
gene id: 696281:DESRU_RS11385
uniprot id: F6DLF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

696281:DESRU RS12055
gene id: 696281:DESRU_RS12055
uniprot id: F6DN39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

696281:DESRU RS00300
gene id: 696281:DESRU_RS00300
uniprot id: F6DL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

696281:DESRU RS12820
gene id: 696281:DESRU_RS12820
uniprot id: F6DPR5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01690
gene id: 696281:DESRU_RS01690
uniprot id: F6DPE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

696281:DESRU RS07130
gene id: 696281:DESRU_RS07130
uniprot id: F6DQ93
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

696281:DESRU RS19200
gene id: 696281:DESRU_RS19200
uniprot id: F6DQL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS02515
gene id: 696281:DESRU_RS02515
uniprot id: F6DS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

696281:DESRU RS14635
gene id: 696281:DESRU_RS14635
uniprot id: F6DSL5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS19590
gene id: 696281:DESRU_RS19590
uniprot id: F6DRF3
names: Similarity
messages: Belongs to the ParB family.

696281:DESRU RS02100
gene id: 696281:DESRU_RS02100
uniprot id: F6DQX5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS16860
gene id: 696281:DESRU_RS16860
uniprot id: F6DKD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS11220
gene id: 696281:DESRU_RS11220
uniprot id: F6DLB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS05805
gene id: 696281:DESRU_RS05805
uniprot id: F6DMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

696281:DESRU RS01580
gene id: 696281:DESRU_RS01580
uniprot id: F6DPC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

696281:DESRU RS04200
gene id: 696281:DESRU_RS04200
uniprot id: F6DV36
names: Similarity
messages: Belongs to the asparagine synthetase family.

696281:DESRU RS11155
gene id: 696281:DESRU_RS11155
uniprot id: F6DKS9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

696281:DESRU RS13725
gene id: 696281:DESRU_RS13725
uniprot id: F6DRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS06655
gene id: 696281:DESRU_RS06655
uniprot id: F6DPK0
names: Similarity
messages: Belongs to the RutC family.

696281:DESRU RS10760
gene id: 696281:DESRU_RS10760
uniprot id: F6DK61
names: Similarity
messages: Belongs to the peptidase M24B family.

696281:DESRU RS09460
gene id: 696281:DESRU_RS09460
uniprot id: F6DU49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

696281:DESRU RS15565
gene id: 696281:DESRU_RS15565
uniprot id: F6DUA5
names: Similarity
messages: Belongs to the asp23 family.

696281:DESRU RS16460
gene id: 696281:DESRU_RS16460
uniprot id: F6DVL1
names: Similarity
messages: Belongs to the FrhG family.

696281:DESRU RS16270
gene id: 696281:DESRU_RS16270
uniprot id: F6DVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

696281:DESRU RS02430
gene id: 696281:DESRU_RS02430
uniprot id: F6DRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS05100
gene id: 696281:DESRU_RS05100
uniprot id: F6DL53
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

696281:DESRU RS11940
gene id: 696281:DESRU_RS11940
uniprot id: F6DMD8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

696281:DESRU RS01860
gene id: 696281:DESRU_RS01860
uniprot id: F6DPI1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

696281:DESRU RS18935
gene id: 696281:DESRU_RS18935
uniprot id: F6DQ15
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

696281:DESRU RS12495
gene id: 696281:DESRU_RS12495
uniprot id: F6DNX7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

696281:DESRU RS05900
gene id: 696281:DESRU_RS05900
uniprot id: F6DMX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

696281:DESRU RS04870
gene id: 696281:DESRU_RS04870
uniprot id: F6DKH1
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS14845
gene id: 696281:DESRU_RS14845
uniprot id: F6DT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

696281:DESRU RS08275
gene id: 696281:DESRU_RS08275
uniprot id: F6DSB2
names: Similarity
messages: Belongs to the Ahb/Nir family.

696281:DESRU RS16815
gene id: 696281:DESRU_RS16815
uniprot id: F6DKC2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS15970
gene id: 696281:DESRU_RS15970
uniprot id: F6DUX5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

696281:DESRU RS01630
gene id: 696281:DESRU_RS01630
uniprot id: F6DPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

696281:DESRU RS11565
gene id: 696281:DESRU_RS11565
uniprot id: F6DLI6
names: Similarity
messages: Belongs to the leucine-binding protein family.

696281:DESRU RS17495
gene id: 696281:DESRU_RS17495
uniprot id: F6DLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

696281:DESRU RS14395
gene id: 696281:DESRU_RS14395
uniprot id: F6DSG5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

696281:DESRU RS12190
gene id: 696281:DESRU_RS12190
uniprot id: F6DN65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS03260
gene id: 696281:DESRU_RS03260
uniprot id: F6DTA6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

696281:DESRU RS13505
gene id: 696281:DESRU_RS13505
uniprot id: F6DQK0
names: Subcellular Location Annotation
messages: Cell membrane

696281:DESRU RS06965
gene id: 696281:DESRU_RS06965
uniprot id: F6DPR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS13005
gene id: 696281:DESRU_RS13005
uniprot id: F6DPV3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

696281:DESRU RS06900
gene id: 696281:DESRU_RS06900
uniprot id: F6DPQ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06280
gene id: 696281:DESRU_RS06280
uniprot id: F6DNQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

696281:DESRU RS14670
gene id: 696281:DESRU_RS14670
uniprot id: F6DSM2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

696281:DESRU RS09235
gene id: 696281:DESRU_RS09235
uniprot id: F6DTL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

696281:DESRU RS11205
gene id: 696281:DESRU_RS11205
uniprot id: F6DLB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

696281:DESRU RS09100
gene id: 696281:DESRU_RS09100
uniprot id: F6DTI8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

696281:DESRU RS14810
gene id: 696281:DESRU_RS14810
uniprot id: F6DT35
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

696281:DESRU RS13855
gene id: 696281:DESRU_RS13855
uniprot id: F6DRC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

696281:DESRU RS06550
gene id: 696281:DESRU_RS06550
uniprot id: F6DNW1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

696281:DESRU RS08000
gene id: 696281:DESRU_RS08000
uniprot id: F6DRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

696281:DESRU RS08750
gene id: 696281:DESRU_RS08750
uniprot id: F6DSY8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

696281:DESRU RS06420
gene id: 696281:DESRU_RS06420
uniprot id: F6DNT4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

696281:DESRU RS10030
gene id: 696281:DESRU_RS10030
uniprot id: F6DUU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

696281:DESRU RS10925
gene id: 696281:DESRU_RS10925
uniprot id: F6DKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS04520
gene id: 696281:DESRU_RS04520
uniprot id: F6DJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS01885
gene id: 696281:DESRU_RS01885
uniprot id: F6DQT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

696281:DESRU RS01400
gene id: 696281:DESRU_RS01400
uniprot id: F6DNM6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

696281:DESRU RS11730
gene id: 696281:DESRU_RS11730
uniprot id: F6DMA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS17530
gene id: 696281:DESRU_RS17530
uniprot id: F6DLN3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS09485
gene id: 696281:DESRU_RS09485
uniprot id: F6DU54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

696281:DESRU RS12610
gene id: 696281:DESRU_RS12610
uniprot id: F6DNZ9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

696281:DESRU RS05305
gene id: 696281:DESRU_RS05305
uniprot id: F6DL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

696281:DESRU RS00840
gene id: 696281:DESRU_RS00840
uniprot id: F6DMQ4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

696281:DESRU RS09975
gene id: 696281:DESRU_RS09975
uniprot id: F6DUT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

696281:DESRU RS13365
gene id: 696281:DESRU_RS13365
uniprot id: F6DQH1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

696281:DESRU RS12825
gene id: 696281:DESRU_RS12825
uniprot id: F6DPR6
names: Similarity
messages: Belongs to the type IA topoisomerase family.

696281:DESRU RS12070
gene id: 696281:DESRU_RS12070
uniprot id: F6DN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

696281:DESRU RS18580
gene id: 696281:DESRU_RS18580
uniprot id: F6DP60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

696281:DESRU RS09715
gene id: 696281:DESRU_RS09715
uniprot id: F6DUN2
names: Similarity
messages: Belongs to the peptidase M16 family.

696281:DESRU RS09575
gene id: 696281:DESRU_RS09575
uniprot id: F6DU72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS00005
gene id: 696281:DESRU_RS00005
uniprot id: F6DKZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

696281:DESRU RS09220
gene id: 696281:DESRU_RS09220
uniprot id: F6DTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

696281:DESRU RS18700
gene id: 696281:DESRU_RS18700
uniprot id: F6DP83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

696281:DESRU RS10600
gene id: 696281:DESRU_RS10600
uniprot id: F6DK34
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

696281:DESRU RS15890
gene id: 696281:DESRU_RS15890
uniprot id: F6DUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

696281:DESRU RS08625
gene id: 696281:DESRU_RS08625
uniprot id: F6DSW2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

696281:DESRU RS00470
gene id: 696281:DESRU_RS00470
uniprot id: F6DLU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS18425
gene id: 696281:DESRU_RS18425
uniprot id: F6DNG8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

696281:DESRU RS07330
gene id: 696281:DESRU_RS07330
uniprot id: F6DQC7
names: Similarity
messages: Belongs to the UPF0047 family.

696281:DESRU RS01375
gene id: 696281:DESRU_RS01375
uniprot id: F6DNM1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

696281:DESRU RS16895
gene id: 696281:DESRU_RS16895
uniprot id: F6DKD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

696281:DESRU RS15115
gene id: 696281:DESRU_RS15115
uniprot id: F6DTM8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS07590
gene id: 696281:DESRU_RS07590
uniprot id: F6DR38
names: Similarity
messages: Belongs to the Tlp family.

696281:DESRU RS14745
gene id: 696281:DESRU_RS14745
uniprot id: F6DT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

696281:DESRU RS08235
gene id: 696281:DESRU_RS08235
uniprot id: F6DSA4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

696281:DESRU RS11800
gene id: 696281:DESRU_RS11800
uniprot id: F6DMB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

696281:DESRU RS18110
gene id: 696281:DESRU_RS18110
uniprot id: F6DNA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

696281:DESRU RS18295
gene id: 696281:DESRU_RS18295
uniprot id: F6DNE2
names: Subcellular Location Annotation
messages: Cytoplasm

696281:DESRU RS19975
gene id: 696281:DESRU_RS19975
uniprot id: F6DT24
names: Similarity
messages: Belongs to the universal stress protein A family.

696281:DESRU RS09695
gene id: 696281:DESRU_RS09695
uniprot id: F6DUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

696281:DESRU RS07465
gene id: 696281:DESRU_RS07465
uniprot id: F6DR13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

696281:DESRU RS01660
gene id: 696281:DESRU_RS01660
uniprot id: F6DPE0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS17130
gene id: 696281:DESRU_RS17130
uniprot id: F6DKX1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

696281:DESRU RS02480
gene id: 696281:DESRU_RS02480
uniprot id: F6DRM0
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01505
gene id: 696281:DESRU_RS01505
uniprot id: F6DPA9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

696281:DESRU RS16780
gene id: 696281:DESRU_RS16780
uniprot id: F6DKB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

696281:DESRU RS03830
gene id: 696281:DESRU_RS03830
uniprot id: F6DUG8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

696281:DESRU RS05200
gene id: 696281:DESRU_RS05200
uniprot id: F6DL73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

696281:DESRU RS06905
gene id: 696281:DESRU_RS06905
uniprot id: F6DPQ1
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

696281:DESRU RS10150
gene id: 696281:DESRU_RS10150
uniprot id: F6DVA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

696281:DESRU RS09410
gene id: 696281:DESRU_RS09410
uniprot id: F6DU39
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS10570
gene id: 696281:DESRU_RS10570
uniprot id: F6DK28
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-822 that is involved in catalysis.

696281:DESRU RS01240
gene id: 696281:DESRU_RS01240
uniprot id: F6DNK1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

696281:DESRU RS10165
gene id: 696281:DESRU_RS10165
uniprot id: F6DVA6
names: Similarity
messages: Belongs to the class-I fumarase family.

696281:DESRU RS01810
gene id: 696281:DESRU_RS01810
uniprot id: F6DPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

696281:DESRU RS07665
gene id: 696281:DESRU_RS07665
uniprot id: F6DR52
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS14185
gene id: 696281:DESRU_RS14185
uniprot id: F6DRZ0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

696281:DESRU RS16310
gene id: 696281:DESRU_RS16310
uniprot id: F6DVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

696281:DESRU RS12545
gene id: 696281:DESRU_RS12545
uniprot id: F6DNY7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

696281:DESRU RS14825
gene id: 696281:DESRU_RS14825
uniprot id: F6DT38
names: Similarity
messages: Belongs to the UPF0735 family.

696281:DESRU RS06940
gene id: 696281:DESRU_RS06940
uniprot id: F6DPQ8
names: Similarity
messages: Belongs to the TrpC family.

696281:DESRU RS16550
gene id: 696281:DESRU_RS16550
uniprot id: F6DVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

696281:DESRU RS13160
gene id: 696281:DESRU_RS13160
uniprot id: F6DPY5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS16955
gene id: 696281:DESRU_RS16955
uniprot id: F6DKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

696281:DESRU RS02985
gene id: 696281:DESRU_RS02985
uniprot id: F6DSQ5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS16260
gene id: 696281:DESRU_RS16260
uniprot id: F6DVH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS06235
gene id: 696281:DESRU_RS06235
uniprot id: F6DNP8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

696281:DESRU RS19555
gene id: 696281:DESRU_RS19555
uniprot id: F6DRE6
names: Similarity
messages: Belongs to the peptidase M18 family.

696281:DESRU RS05875
gene id: 696281:DESRU_RS05875
uniprot id: F6DMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS04725
gene id: 696281:DESRU_RS04725
uniprot id: F6DJY9
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

696281:DESRU RS06440
gene id: 696281:DESRU_RS06440
uniprot id: F6DNT8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

696281:DESRU RS09185
gene id: 696281:DESRU_RS09185
uniprot id: F6DTK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

696281:DESRU RS02720
gene id: 696281:DESRU_RS02720
uniprot id: F6DS60
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

696281:DESRU RS05135
gene id: 696281:DESRU_RS05135
uniprot id: F6DL61
names: Similarity
messages: Belongs to the peptidase S16 family.

696281:DESRU RS14665
gene id: 696281:DESRU_RS14665
uniprot id: F6DSM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

696281:DESRU RS10905
gene id: 696281:DESRU_RS10905
uniprot id: F6DKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS16975
gene id: 696281:DESRU_RS16975
uniprot id: F6DKU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS01590
gene id: 696281:DESRU_RS01590
uniprot id: F6DPC6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

696281:DESRU RS13090
gene id: 696281:DESRU_RS13090
uniprot id: F6DPX0
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

696281:DESRU RS01190
gene id: 696281:DESRU_RS01190
uniprot id: F6DNJ1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

696281:DESRU RS18080
gene id: 696281:DESRU_RS18080
uniprot id: F6DN99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

696281:DESRU RS19220
gene id: 696281:DESRU_RS19220
uniprot id: F6DQM3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

696281:DESRU RS12195
gene id: 696281:DESRU_RS12195
uniprot id: F6DN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

696281:DESRU RS05820
gene id: 696281:DESRU_RS05820
uniprot id: F6DMW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

696281:DESRU RS06610
gene id: 696281:DESRU_RS06610
uniprot id: F6DPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

696281:DESRU RS10825
gene id: 696281:DESRU_RS10825
uniprot id: F6DKL3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

696281:DESRU RS01935
gene id: 696281:DESRU_RS01935
uniprot id: F6DQU4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

696281:DESRU RS04425
gene id: 696281:DESRU_RS04425
uniprot id: F6DV78
names: Similarity
messages: Belongs to the peptidase C40 family.

696281:DESRU RS17215
gene id: 696281:DESRU_RS17215
uniprot id: F6DKY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

696281:DESRU RS00350
gene id: 696281:DESRU_RS00350
uniprot id: F6DLS3
names: Similarity
messages: Belongs to the ArsC family.

696281:DESRU RS12060
gene id: 696281:DESRU_RS12060
uniprot id: F6DN40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

696281:DESRU RS13030
gene id: 696281:DESRU_RS13030
uniprot id: F6DPV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

696281:DESRU RS16295
gene id: 696281:DESRU_RS16295
uniprot id: F6DVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS08680
gene id: 696281:DESRU_RS08680
uniprot id: F6DSX4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

696281:DESRU RS17555
gene id: 696281:DESRU_RS17555
uniprot id: F6DLN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

696281:DESRU RS19455
gene id: 696281:DESRU_RS19455
uniprot id: F6DQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

696281:DESRU RS14605
gene id: 696281:DESRU_RS14605
uniprot id: F6DSK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

696281:DESRU RS14285
gene id: 696281:DESRU_RS14285
uniprot id: F6DS12
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

696281:DESRU RS08005
gene id: 696281:DESRU_RS08005
uniprot id: F6DRS7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

696281:DESRU RS01655
gene id: 696281:DESRU_RS01655
uniprot id: F6DPD9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

696281:DESRU RS18830
gene id: 696281:DESRU_RS18830
uniprot id: F6DPZ5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

696281:DESRU RS16900
gene id: 696281:DESRU_RS16900
uniprot id: F6DKE0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01515
gene id: 696281:DESRU_RS01515
uniprot id: F6DPB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

696281:DESRU RS04215
gene id: 696281:DESRU_RS04215
uniprot id: F6DV38
names: Similarity
messages: Belongs to the glutamine synthetase family.

696281:DESRU RS17440
gene id: 696281:DESRU_RS17440
uniprot id: F6DLL5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

696281:DESRU RS12995
gene id: 696281:DESRU_RS12995
uniprot id: F6DPV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

696281:DESRU RS04760
gene id: 696281:DESRU_RS04760
uniprot id: F6DJZ6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

696281:DESRU RS16335
gene id: 696281:DESRU_RS16335
uniprot id: F6DVI6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

696281:DESRU RS18590
gene id: 696281:DESRU_RS18590
uniprot id: F6DP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

696281:DESRU RS01500
gene id: 696281:DESRU_RS01500
uniprot id: F6DPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

696281:DESRU RS08705
gene id: 696281:DESRU_RS08705
uniprot id: F6DSX9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

696281:DESRU RS18065
gene id: 696281:DESRU_RS18065
uniprot id: F6DMM6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

696281:DESRU RS08130
gene id: 696281:DESRU_RS08130
uniprot id: F6DRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

696281:DESRU RS10385
gene id: 696281:DESRU_RS10385
uniprot id: F6DVF1
names: Similarity
messages: Belongs to the peptidase A31 family.

696281:DESRU RS16480
gene id: 696281:DESRU_RS16480
uniprot id: F6DVL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS10355
gene id: 696281:DESRU_RS10355
uniprot id: F6DVE5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS09175
gene id: 696281:DESRU_RS09175
uniprot id: F6DTK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

696281:DESRU RS08830
gene id: 696281:DESRU_RS08830
uniprot id: F6DT03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

696281:DESRU RS01520
gene id: 696281:DESRU_RS01520
uniprot id: F6DPB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

696281:DESRU RS19505
gene id: 696281:DESRU_RS19505
uniprot id: F6DQS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

696281:DESRU RS01430
gene id: 696281:DESRU_RS01430
uniprot id: F6DNN2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS10935
gene id: 696281:DESRU_RS10935
uniprot id: F6DKN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS00465
gene id: 696281:DESRU_RS00465
uniprot id: F6DLU5
names: Similarity
messages: Belongs to the UxaA family.

696281:DESRU RS14175
gene id: 696281:DESRU_RS14175
uniprot id: F6DRY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS01700
gene id: 696281:DESRU_RS01700
uniprot id: F6DPE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

696281:DESRU RS05950
gene id: 696281:DESRU_RS05950
uniprot id: F6DMY6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

696281:DESRU RS07680
gene id: 696281:DESRU_RS07680
uniprot id: F6DR55
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS01085
gene id: 696281:DESRU_RS01085
uniprot id: F6DMV3
names: Similarity
messages: Belongs to the HdrA family.

696281:DESRU RS11590
gene id: 696281:DESRU_RS11590
uniprot id: F6DM72
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS18815
gene id: 696281:DESRU_RS18815
uniprot id: F6DPZ2
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS11710
gene id: 696281:DESRU_RS11710
uniprot id: F6DM97
names: Similarity
messages: Belongs to the RemA family.

696281:DESRU RS18585
gene id: 696281:DESRU_RS18585
uniprot id: F6DP61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

696281:DESRU RS16400
gene id: 696281:DESRU_RS16400
uniprot id: F6DVJ9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

696281:DESRU RS02595
gene id: 696281:DESRU_RS02595
uniprot id: F6DS35
names: Similarity
messages: Belongs to the CFA/CMAS family.

696281:DESRU RS07085
gene id: 696281:DESRU_RS07085
uniprot id: F6DQ85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

696281:DESRU RS01050
gene id: 696281:DESRU_RS01050
uniprot id: F6DMU6
names: Similarity
messages: Belongs to the HdrA family.

696281:DESRU RS05230
gene id: 696281:DESRU_RS05230
uniprot id: F6DL79
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

696281:DESRU RS06890
gene id: 696281:DESRU_RS06890
uniprot id: F6DPP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

696281:DESRU RS07350
gene id: 696281:DESRU_RS07350
uniprot id: F6DQD1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS02180
gene id: 696281:DESRU_RS02180
uniprot id: F6DQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

696281:DESRU RS10340
gene id: 696281:DESRU_RS10340
uniprot id: F6DVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS05725
gene id: 696281:DESRU_RS05725
uniprot id: F6DM57
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

696281:DESRU RS18220
gene id: 696281:DESRU_RS18220
uniprot id: F6DNC7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

696281:DESRU RS02000
gene id: 696281:DESRU_RS02000
uniprot id: F6DQV8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS02065
gene id: 696281:DESRU_RS02065
uniprot id: F6DQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

696281:DESRU RS04585
gene id: 696281:DESRU_RS04585
uniprot id: F6DJW1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

696281:DESRU RS06275
gene id: 696281:DESRU_RS06275
uniprot id: F6DNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

696281:DESRU RS04600
gene id: 696281:DESRU_RS04600
uniprot id: F6DJW4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

696281:DESRU RS14430
gene id: 696281:DESRU_RS14430
uniprot id: F6DSH2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

696281:DESRU RS07700
gene id: 696281:DESRU_RS07700
uniprot id: F6DR59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS11725
gene id: 696281:DESRU_RS11725
uniprot id: F6DMA0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS09165
gene id: 696281:DESRU_RS09165
uniprot id: F6DTK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

696281:DESRU RS01605
gene id: 696281:DESRU_RS01605
uniprot id: F6DPC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS00400
gene id: 696281:DESRU_RS00400
uniprot id: F6DLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS02260
gene id: 696281:DESRU_RS02260
uniprot id: F6DRH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

696281:DESRU RS04465
gene id: 696281:DESRU_RS04465
uniprot id: F6DJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

696281:DESRU RS05880
gene id: 696281:DESRU_RS05880
uniprot id: F6DMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

696281:DESRU RS01755
gene id: 696281:DESRU_RS01755
uniprot id: F6DPG0
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01280
gene id: 696281:DESRU_RS01280
uniprot id: F6DNK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS15325
gene id: 696281:DESRU_RS15325
uniprot id: F6DTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

696281:DESRU RS05955
gene id: 696281:DESRU_RS05955
uniprot id: F6DMY7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

696281:DESRU RS03810
gene id: 696281:DESRU_RS03810
uniprot id: F6DUG4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

696281:DESRU RS16845
gene id: 696281:DESRU_RS16845
uniprot id: F6DKC9
names: Similarity
messages: Belongs to the UPF0749 family.

696281:DESRU RS11995
gene id: 696281:DESRU_RS11995
uniprot id: F6DN27
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

696281:DESRU RS01900
gene id: 696281:DESRU_RS01900
uniprot id: F6DQT8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

696281:DESRU RS07540
gene id: 696281:DESRU_RS07540
uniprot id: F6DR28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS15030
gene id: 696281:DESRU_RS15030
uniprot id: F6DT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

696281:DESRU RS00920
gene id: 696281:DESRU_RS00920
uniprot id: F6DMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

696281:DESRU RS07970
gene id: 696281:DESRU_RS07970
uniprot id: F6DRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

696281:DESRU RS18740
gene id: 696281:DESRU_RS18740
uniprot id: F6DP91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS08570
gene id: 696281:DESRU_RS08570
uniprot id: F6DSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

696281:DESRU RS08290
gene id: 696281:DESRU_RS08290
uniprot id: F6DSB5
names: Similarity
messages: Belongs to the UPF0145 family.

696281:DESRU RS11825
gene id: 696281:DESRU_RS11825
uniprot id: F6DMB6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS14385
gene id: 696281:DESRU_RS14385
uniprot id: F6DSG3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

696281:DESRU RS04850
gene id: 696281:DESRU_RS04850
uniprot id: F6DKG7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS03390
gene id: 696281:DESRU_RS03390
uniprot id: F6DTD2
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS14305
gene id: 696281:DESRU_RS14305
uniprot id: F6DS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

696281:DESRU RS18360
gene id: 696281:DESRU_RS18360
uniprot id: F6DNF5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

696281:DESRU RS06400
gene id: 696281:DESRU_RS06400
uniprot id: F6DNT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

696281:DESRU RS05235
gene id: 696281:DESRU_RS05235
uniprot id: F6DL80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

696281:DESRU RS18525
gene id: 696281:DESRU_RS18525
uniprot id: F6DP49
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS11680
gene id: 696281:DESRU_RS11680
uniprot id: F6DM91
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

696281:DESRU RS15270
gene id: 696281:DESRU_RS15270
uniprot id: F6DTQ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS01845
gene id: 696281:DESRU_RS01845
uniprot id: F6DPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

696281:DESRU RS15830
gene id: 696281:DESRU_RS15830
uniprot id: F6DUF8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

696281:DESRU RS08460
gene id: 696281:DESRU_RS08460
uniprot id: F6DSE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS15510
gene id: 696281:DESRU_RS15510
uniprot id: F6DU94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

696281:DESRU RS15815
gene id: 696281:DESRU_RS15815
uniprot id: F6DUF5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

696281:DESRU RS15480
gene id: 696281:DESRU_RS15480
uniprot id: F6DU88
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

696281:DESRU RS15930
gene id: 696281:DESRU_RS15930
uniprot id: F6DUW7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS11020
gene id: 696281:DESRU_RS11020
uniprot id: F6DKQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS10590
gene id: 696281:DESRU_RS10590
uniprot id: F6DK32
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

696281:DESRU RS02300
gene id: 696281:DESRU_RS02300
uniprot id: F6DRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

696281:DESRU RS14410
gene id: 696281:DESRU_RS14410
uniprot id: F6DSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

696281:DESRU RS03895
gene id: 696281:DESRU_RS03895
uniprot id: F6DUI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

696281:DESRU RS00695
gene id: 696281:DESRU_RS00695
uniprot id: F6DLY9
names: Similarity
messages: Belongs to the ThiD family.

696281:DESRU RS14000
gene id: 696281:DESRU_RS14000
uniprot id: F6DRW4
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS16240
gene id: 696281:DESRU_RS16240
uniprot id: F6DVG6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS14205
gene id: 696281:DESRU_RS14205
uniprot id: F6DRZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

696281:DESRU RS10075
gene id: 696281:DESRU_RS10075
uniprot id: F6DV88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

696281:DESRU RS11625
gene id: 696281:DESRU_RS11625
uniprot id: F6DM80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

696281:DESRU RS07555
gene id: 696281:DESRU_RS07555
uniprot id: F6DR31
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

696281:DESRU RS16670
gene id: 696281:DESRU_RS16670
uniprot id: F6DK94
names: Similarity
messages: Belongs to the YggT family.

696281:DESRU RS08255
gene id: 696281:DESRU_RS08255
uniprot id: F6DSA8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

696281:DESRU RS18635
gene id: 696281:DESRU_RS18635
uniprot id: F6DP71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS02465
gene id: 696281:DESRU_RS02465
uniprot id: F6DRL7
names: Similarity
messages: Belongs to the UPF0597 family.

696281:DESRU RS00505
gene id: 696281:DESRU_RS00505
uniprot id: F6DLV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

696281:DESRU RS01550
gene id: 696281:DESRU_RS01550
uniprot id: F6DPB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

696281:DESRU RS04710
gene id: 696281:DESRU_RS04710
uniprot id: F6DJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

696281:DESRU RS07480
gene id: 696281:DESRU_RS07480
uniprot id: F6DR16
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS04845
gene id: 696281:DESRU_RS04845
uniprot id: F6DKG6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

696281:DESRU RS09225
gene id: 696281:DESRU_RS09225
uniprot id: F6DTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

696281:DESRU RS11215
gene id: 696281:DESRU_RS11215
uniprot id: F6DLB7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

696281:DESRU RS00070
gene id: 696281:DESRU_RS00070
uniprot id: F6DL10
names: Similarity
messages: Belongs to the RutC family.

696281:DESRU RS09260
gene id: 696281:DESRU_RS09260
uniprot id: F6DTM0
names: Similarity
messages: Belongs to the UPF0102 family.

696281:DESRU RS09540
gene id: 696281:DESRU_RS09540
uniprot id: F6DU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

696281:DESRU RS16925
gene id: 696281:DESRU_RS16925
uniprot id: F6DKE5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

696281:DESRU RS10980
gene id: 696281:DESRU_RS10980
uniprot id: F6DKP2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

696281:DESRU RS06515
gene id: 696281:DESRU_RS06515
uniprot id: F6DNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

696281:DESRU RS02410
gene id: 696281:DESRU_RS02410
uniprot id: F6DRK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS03790
gene id: 696281:DESRU_RS03790
uniprot id: F6DUG0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

696281:DESRU RS18800
gene id: 696281:DESRU_RS18800
uniprot id: F6DPA4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

696281:DESRU RS01200
gene id: 696281:DESRU_RS01200
uniprot id: F6DNJ3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

696281:DESRU RS05105
gene id: 696281:DESRU_RS05105
uniprot id: F6DL54
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

696281:DESRU RS08105
gene id: 696281:DESRU_RS08105
uniprot id: F6DRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS11910
gene id: 696281:DESRU_RS11910
uniprot id: F6DMD2
names: Similarity
messages: Belongs to the GerABKA family.

696281:DESRU RS01825
gene id: 696281:DESRU_RS01825
uniprot id: F6DPH4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

696281:DESRU RS09495
gene id: 696281:DESRU_RS09495
uniprot id: F6DU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

696281:DESRU RS08265
gene id: 696281:DESRU_RS08265
uniprot id: F6DSB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

696281:DESRU RS13450
gene id: 696281:DESRU_RS13450
uniprot id: F6DQI9
names: Similarity
messages: Belongs to the peptidase S16 family.

696281:DESRU RS06060
gene id: 696281:DESRU_RS06060
uniprot id: F6DN03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

696281:DESRU RS10055
gene id: 696281:DESRU_RS10055
uniprot id: F6DV84
names: Similarity
messages: Belongs to the histone deacetylase family.

696281:DESRU RS05920
gene id: 696281:DESRU_RS05920
uniprot id: F6DMY0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

696281:DESRU RS11330
gene id: 696281:DESRU_RS11330
uniprot id: F6DLE2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS09300
gene id: 696281:DESRU_RS09300
uniprot id: F6DU17
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

696281:DESRU RS16385
gene id: 696281:DESRU_RS16385
uniprot id: F6DVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

696281:DESRU RS04795
gene id: 696281:DESRU_RS04795
uniprot id: F6DKF6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01920
gene id: 696281:DESRU_RS01920
uniprot id: F6DQU2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

696281:DESRU RS00745
gene id: 696281:DESRU_RS00745
uniprot id: F6DMN4
names: Similarity
messages: Belongs to the DtxR/MntR family.

696281:DESRU RS16415
gene id: 696281:DESRU_RS16415
uniprot id: F6DVK2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

696281:DESRU RS04720
gene id: 696281:DESRU_RS04720
uniprot id: F6DJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

696281:DESRU RS17455
gene id: 696281:DESRU_RS17455
uniprot id: F6DLL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS16920
gene id: 696281:DESRU_RS16920
uniprot id: F6DKE4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

696281:DESRU RS04505
gene id: 696281:DESRU_RS04505
uniprot id: F6DJU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

696281:DESRU RS18285
gene id: 696281:DESRU_RS18285
uniprot id: F6DNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

696281:DESRU RS06050
gene id: 696281:DESRU_RS06050
uniprot id: F6DN01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

696281:DESRU RS14545
gene id: 696281:DESRU_RS14545
uniprot id: F6DSJ8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

696281:DESRU RS07945
gene id: 696281:DESRU_RS07945
uniprot id: F6DRR6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

696281:DESRU RS09380
gene id: 696281:DESRU_RS09380
uniprot id: F6DU32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

696281:DESRU RS01770
gene id: 696281:DESRU_RS01770
uniprot id: F6DPG3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

696281:DESRU RS02485
gene id: 696281:DESRU_RS02485
uniprot id: F6DRM1
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS18630
gene id: 696281:DESRU_RS18630
uniprot id: F6DP70
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

696281:DESRU RS15035
gene id: 696281:DESRU_RS15035
uniprot id: F6DT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

696281:DESRU RS04150
gene id: 696281:DESRU_RS04150
uniprot id: F6DV26
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS03870
gene id: 696281:DESRU_RS03870
uniprot id: F6DUH5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

696281:DESRU RS05890
gene id: 696281:DESRU_RS05890
uniprot id: F6DMX4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

696281:DESRU RS15670
gene id: 696281:DESRU_RS15670
uniprot id: F6DUC6
names: Similarity
messages: Belongs to the peptidase U62 family.

696281:DESRU RS04540
gene id: 696281:DESRU_RS04540
uniprot id: F6DJV2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

696281:DESRU RS16940
gene id: 696281:DESRU_RS16940
uniprot id: F6DKE8
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS11410
gene id: 696281:DESRU_RS11410
uniprot id: F6DLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

696281:DESRU RS12700
gene id: 696281:DESRU_RS12700
uniprot id: F6DP15
names: Similarity
messages: Belongs to the transglycosylase Slt family.

696281:DESRU RS05780
gene id: 696281:DESRU_RS05780
uniprot id: F6DM68
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

696281:DESRU RS12025
gene id: 696281:DESRU_RS12025
uniprot id: F6DN33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

696281:DESRU RS13375
gene id: 696281:DESRU_RS13375
uniprot id: F6DQH3
names: Similarity
messages: Belongs to the threonine synthase family.

696281:DESRU RS08425
gene id: 696281:DESRU_RS08425
uniprot id: F6DSD7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS16520
gene id: 696281:DESRU_RS16520
uniprot id: F6DVM3
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS14010
gene id: 696281:DESRU_RS14010
uniprot id: F6DRW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS09520
gene id: 696281:DESRU_RS09520
uniprot id: F6DU61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

696281:DESRU RS01855
gene id: 696281:DESRU_RS01855
uniprot id: F6DPI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06080
gene id: 696281:DESRU_RS06080
uniprot id: F6DN05
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

696281:DESRU RS15055
gene id: 696281:DESRU_RS15055
uniprot id: F6DT84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

696281:DESRU RS16455
gene id: 696281:DESRU_RS16455
uniprot id: F6DVL0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

696281:DESRU RS12315
gene id: 696281:DESRU_RS12315
uniprot id: F6DN83
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

696281:DESRU RS11805
gene id: 696281:DESRU_RS11805
uniprot id: F6DMB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

696281:DESRU RS15655
gene id: 696281:DESRU_RS15655
uniprot id: F6DUC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

696281:DESRU RS13010
gene id: 696281:DESRU_RS13010
uniprot id: F6DPV4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS02095
gene id: 696281:DESRU_RS02095
uniprot id: F6DQX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

696281:DESRU RS11700
gene id: 696281:DESRU_RS11700
uniprot id: F6DM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

696281:DESRU RS02965
gene id: 696281:DESRU_RS02965
uniprot id: F6DSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS02505
gene id: 696281:DESRU_RS02505
uniprot id: F6DRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

696281:DESRU RS02365
gene id: 696281:DESRU_RS02365
uniprot id: F6DRJ7
names: Similarity
messages: Belongs to the GSP E family.

696281:DESRU RS01355
gene id: 696281:DESRU_RS01355
uniprot id: F6DNL7
names: Similarity
messages: Belongs to the CtsR family.

696281:DESRU RS10020
gene id: 696281:DESRU_RS10020
uniprot id: F6DUU0
names: Similarity
messages: Belongs to the TPP enzyme family.

696281:DESRU RS18845
gene id: 696281:DESRU_RS18845
uniprot id: F6DPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

696281:DESRU RS06810
gene id: 696281:DESRU_RS06810
uniprot id: F6DPN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

696281:DESRU RS11300
gene id: 696281:DESRU_RS11300
uniprot id: F6DLD5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

696281:DESRU RS11595
gene id: 696281:DESRU_RS11595
uniprot id: F6DM73
names: Similarity
messages: Belongs to the leucine-binding protein family.

696281:DESRU RS13540
gene id: 696281:DESRU_RS13540
uniprot id: F6DQK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS03910
gene id: 696281:DESRU_RS03910
uniprot id: F6DUI3
names: Similarity
messages: Belongs to the RutC family.

696281:DESRU RS01870
gene id: 696281:DESRU_RS01870
uniprot id: F6DPI3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06860
gene id: 696281:DESRU_RS06860
uniprot id: F6DPP2
names: Similarity
messages: Belongs to the peptidase C40 family.

696281:DESRU RS03105
gene id: 696281:DESRU_RS03105
uniprot id: F6DSS5
names: Similarity
messages: Belongs to the hexokinase family.

696281:DESRU RS13170
gene id: 696281:DESRU_RS13170
uniprot id: F6DPY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS07150
gene id: 696281:DESRU_RS07150
uniprot id: F6DQ97
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

696281:DESRU RS11390
gene id: 696281:DESRU_RS11390
uniprot id: F6DLF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

696281:DESRU RS19460
gene id: 696281:DESRU_RS19460
uniprot id: F6DQS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS00915
gene id: 696281:DESRU_RS00915
uniprot id: F6DMR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

696281:DESRU RS04375
gene id: 696281:DESRU_RS04375
uniprot id: F6DV68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS03900
gene id: 696281:DESRU_RS03900
uniprot id: F6DUI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS08060
gene id: 696281:DESRU_RS08060
uniprot id: F6DRT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS14780
gene id: 696281:DESRU_RS14780
uniprot id: F6DT29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS12590
gene id: 696281:DESRU_RS12590
uniprot id: F6DNZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

696281:DESRU RS13955
gene id: 696281:DESRU_RS13955
uniprot id: F6DRV5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS09505
gene id: 696281:DESRU_RS09505
uniprot id: F6DU58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

696281:DESRU RS11560
gene id: 696281:DESRU_RS11560
uniprot id: F6DLI5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS13045
gene id: 696281:DESRU_RS13045
uniprot id: F6DPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS02435
gene id: 696281:DESRU_RS02435
uniprot id: F6DRL1
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS15740
gene id: 696281:DESRU_RS15740
uniprot id: F6DUE0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01230
gene id: 696281:DESRU_RS01230
uniprot id: F6DNJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

696281:DESRU RS09215
gene id: 696281:DESRU_RS09215
uniprot id: F6DTL1
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

696281:DESRU RS10190
gene id: 696281:DESRU_RS10190
uniprot id: F6DVB1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

696281:DESRU RS01610
gene id: 696281:DESRU_RS01610
uniprot id: F6DPD0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

696281:DESRU RS01620
gene id: 696281:DESRU_RS01620
uniprot id: F6DPD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

696281:DESRU RS16865
gene id: 696281:DESRU_RS16865
uniprot id: F6DKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

696281:DESRU RS09545
gene id: 696281:DESRU_RS09545
uniprot id: F6DU66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

696281:DESRU RS11975
gene id: 696281:DESRU_RS11975
uniprot id: F6DME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

696281:DESRU RS14950
gene id: 696281:DESRU_RS14950
uniprot id: F6DT61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS07550
gene id: 696281:DESRU_RS07550
uniprot id: F6DR30
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

696281:DESRU RS00860
gene id: 696281:DESRU_RS00860
uniprot id: F6DMQ8
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

696281:DESRU RS03860
gene id: 696281:DESRU_RS03860
uniprot id: F6DUH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

696281:DESRU RS18975
gene id: 696281:DESRU_RS18975
uniprot id: F6DQ25
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS06560
gene id: 696281:DESRU_RS06560
uniprot id: F6DNW3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

696281:DESRU RS08810
gene id: 696281:DESRU_RS08810
uniprot id: F6DSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

696281:DESRU RS12030
gene id: 696281:DESRU_RS12030
uniprot id: F6DN34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

696281:DESRU RS14400
gene id: 696281:DESRU_RS14400
uniprot id: F6DSG6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS11445
gene id: 696281:DESRU_RS11445
uniprot id: F6DLG2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS09560
gene id: 696281:DESRU_RS09560
uniprot id: F6DU69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

696281:DESRU RS00700
gene id: 696281:DESRU_RS00700
uniprot id: F6DLZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

696281:DESRU RS15850
gene id: 696281:DESRU_RS15850
uniprot id: F6DUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS00820
gene id: 696281:DESRU_RS00820
uniprot id: F6DMQ0
names: Similarity
messages: Belongs to the peptidase S8 family.

696281:DESRU RS13585
gene id: 696281:DESRU_RS13585
uniprot id: F6DR75
names: Similarity
messages: Belongs to the UPF0251 family.

696281:DESRU RS10285
gene id: 696281:DESRU_RS10285
uniprot id: F6DVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS14600
gene id: 696281:DESRU_RS14600
uniprot id: F6DSK8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

696281:DESRU RS19530
gene id: 696281:DESRU_RS19530
uniprot id: F6DQT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

696281:DESRU RS01565
gene id: 696281:DESRU_RS01565
uniprot id: F6DPC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

696281:DESRU RS10070
gene id: 696281:DESRU_RS10070
uniprot id: F6DV87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS10750
gene id: 696281:DESRU_RS10750
uniprot id: F6DK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS10335
gene id: 696281:DESRU_RS10335
uniprot id: F6DVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS01595
gene id: 696281:DESRU_RS01595
uniprot id: F6DPC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

696281:DESRU RS06385
gene id: 696281:DESRU_RS06385
uniprot id: F6DNS7
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

696281:DESRU RS01705
gene id: 696281:DESRU_RS01705
uniprot id: F6DPE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

696281:DESRU RS04810
gene id: 696281:DESRU_RS04810
uniprot id: F6DKF9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS14405
gene id: 696281:DESRU_RS14405
uniprot id: F6DSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

696281:DESRU RS14055
gene id: 696281:DESRU_RS14055
uniprot id: F6DRX2
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS06190
gene id: 696281:DESRU_RS06190
uniprot id: F6DNN9
names: Similarity
messages: Belongs to the FlgM family.

696281:DESRU RS02130
gene id: 696281:DESRU_RS02130
uniprot id: F6DQY1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS01725
gene id: 696281:DESRU_RS01725
uniprot id: F6DPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

696281:DESRU RS09465
gene id: 696281:DESRU_RS09465
uniprot id: F6DU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

696281:DESRU RS10035
gene id: 696281:DESRU_RS10035
uniprot id: F6DUU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS16990
gene id: 696281:DESRU_RS16990
uniprot id: F6DKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

696281:DESRU RS01525
gene id: 696281:DESRU_RS01525
uniprot id: F6DPB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

696281:DESRU RS16395
gene id: 696281:DESRU_RS16395
uniprot id: F6DVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

696281:DESRU RS09255
gene id: 696281:DESRU_RS09255
uniprot id: F6DTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

696281:DESRU RS16330
gene id: 696281:DESRU_RS16330
uniprot id: F6DVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS06355
gene id: 696281:DESRU_RS06355
uniprot id: F6DNS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18655
gene id: 696281:DESRU_RS18655
uniprot id: F6DP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

696281:DESRU RS17010
gene id: 696281:DESRU_RS17010
uniprot id: F6DKU7
names: Similarity
messages: Belongs to the HdrA family.

696281:DESRU RS06390
gene id: 696281:DESRU_RS06390
uniprot id: F6DNS8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

696281:DESRU RS05130
gene id: 696281:DESRU_RS05130
uniprot id: F6DL60
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

696281:DESRU RS10495
gene id: 696281:DESRU_RS10495
uniprot id: F6DK13
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

696281:DESRU RS14940
gene id: 696281:DESRU_RS14940
uniprot id: F6DT59
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

696281:DESRU RS19045
gene id: 696281:DESRU_RS19045
uniprot id: F6DQ39
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

696281:DESRU RS07030
gene id: 696281:DESRU_RS07030
uniprot id: F6DQ74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS15845
gene id: 696281:DESRU_RS15845
uniprot id: F6DUU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS08125
gene id: 696281:DESRU_RS08125
uniprot id: F6DRV1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS04010
gene id: 696281:DESRU_RS04010
uniprot id: F6DUK0
names: Similarity
messages: Belongs to the P(II) protein family.

696281:DESRU RS05745
gene id: 696281:DESRU_RS05745
uniprot id: F6DM61
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

696281:DESRU RS10725
gene id: 696281:DESRU_RS10725
uniprot id: F6DK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

696281:DESRU RS00310
gene id: 696281:DESRU_RS00310
uniprot id: F6DL49
names: Similarity
messages: Belongs to the manganese catalase family.

696281:DESRU RS11810
gene id: 696281:DESRU_RS11810
uniprot id: F6DMB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

696281:DESRU RS05960
gene id: 696281:DESRU_RS05960
uniprot id: F6DMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

696281:DESRU RS07410
gene id: 696281:DESRU_RS07410
uniprot id: F6DR02
names: Similarity
messages: Belongs to the universal stress protein A family.

696281:DESRU RS06500
gene id: 696281:DESRU_RS06500
uniprot id: F6DNV0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

696281:DESRU RS08540
gene id: 696281:DESRU_RS08540
uniprot id: F6DSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

696281:DESRU RS01395
gene id: 696281:DESRU_RS01395
uniprot id: F6DNM5
names: Similarity
messages: Belongs to the ycf81 family.

696281:DESRU RS12290
gene id: 696281:DESRU_RS12290
uniprot id: F6DN79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

696281:DESRU RS10460
gene id: 696281:DESRU_RS10460
uniprot id: F6DK05
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS14765
gene id: 696281:DESRU_RS14765
uniprot id: F6DT26
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

696281:DESRU RS01615
gene id: 696281:DESRU_RS01615
uniprot id: F6DPD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

696281:DESRU RS17390
gene id: 696281:DESRU_RS17390
uniprot id: F6DLK5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

696281:DESRU RS05180
gene id: 696281:DESRU_RS05180
uniprot id: F6DL70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

696281:DESRU RS11485
gene id: 696281:DESRU_RS11485
uniprot id: F6DLH0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS10220
gene id: 696281:DESRU_RS10220
uniprot id: F6DVB8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS13705
gene id: 696281:DESRU_RS13705
uniprot id: F6DR98
names: Similarity
messages: Belongs to the UPRTase family.

696281:DESRU RS01730
gene id: 696281:DESRU_RS01730
uniprot id: F6DPF4
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS18875
gene id: 696281:DESRU_RS18875
uniprot id: F6DQ03
names: Similarity
messages: Belongs to the ParB family.

696281:DESRU RS18090
gene id: 696281:DESRU_RS18090
uniprot id: F6DNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

696281:DESRU RS01675
gene id: 696281:DESRU_RS01675
uniprot id: F6DPE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

696281:DESRU RS11985
gene id: 696281:DESRU_RS11985
uniprot id: F6DME7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

696281:DESRU RS01910
gene id: 696281:DESRU_RS01910
uniprot id: F6DQU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

696281:DESRU RS16450
gene id: 696281:DESRU_RS16450
uniprot id: F6DVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

696281:DESRU RS08640
gene id: 696281:DESRU_RS08640
uniprot id: F6DSW5
names: Similarity
messages: Belongs to the UxaA family.

696281:DESRU RS16000
gene id: 696281:DESRU_RS16000
uniprot id: F6DUY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS11900
gene id: 696281:DESRU_RS11900
uniprot id: F6DMD0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS11735
gene id: 696281:DESRU_RS11735
uniprot id: F6DMA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS07035
gene id: 696281:DESRU_RS07035
uniprot id: F6DQ75
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

696281:DESRU RS15470
gene id: 696281:DESRU_RS15470
uniprot id: F6DU86
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS01815
gene id: 696281:DESRU_RS01815
uniprot id: F6DPH2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

696281:DESRU RS14935
gene id: 696281:DESRU_RS14935
uniprot id: F6DT58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

696281:DESRU RS17335
gene id: 696281:DESRU_RS17335
uniprot id: F6DLJ3
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

696281:DESRU RS14340
gene id: 696281:DESRU_RS14340
uniprot id: F6DSF4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

696281:DESRU RS01670
gene id: 696281:DESRU_RS01670
uniprot id: F6DPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

696281:DESRU RS10060
gene id: 696281:DESRU_RS10060
uniprot id: F6DV85
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

696281:DESRU RS15840
gene id: 696281:DESRU_RS15840
uniprot id: F6DUU8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

696281:DESRU RS10860
gene id: 696281:DESRU_RS10860
uniprot id: F6DKM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS03735
gene id: 696281:DESRU_RS03735
uniprot id: F6DTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

696281:DESRU RS06330
gene id: 696281:DESRU_RS06330
uniprot id: F6DNR6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

696281:DESRU RS10685
gene id: 696281:DESRU_RS10685
uniprot id: F6DK46
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

696281:DESRU RS03890
gene id: 696281:DESRU_RS03890
uniprot id: F6DUH9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS00950
gene id: 696281:DESRU_RS00950
uniprot id: F6DMS6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

696281:DESRU RS16605
gene id: 696281:DESRU_RS16605
uniprot id: F6DK82
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS08150
gene id: 696281:DESRU_RS08150
uniprot id: F6DS87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

696281:DESRU RS18775
gene id: 696281:DESRU_RS18775
uniprot id: F6DP98
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

696281:DESRU RS09490
gene id: 696281:DESRU_RS09490
uniprot id: F6DU55
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

696281:DESRU RS10745
gene id: 696281:DESRU_RS10745
uniprot id: F6DK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS07940
gene id: 696281:DESRU_RS07940
uniprot id: F6DRR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

696281:DESRU RS01965
gene id: 696281:DESRU_RS01965
uniprot id: F6DQV1
names: Similarity
messages: Belongs to the Fur family.

696281:DESRU RS09345
gene id: 696281:DESRU_RS09345
uniprot id: F6DU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS09880
gene id: 696281:DESRU_RS09880
uniprot id: F6DUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

696281:DESRU RS06185
gene id: 696281:DESRU_RS06185
uniprot id: F6DN25
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

696281:DESRU RS14685
gene id: 696281:DESRU_RS14685
uniprot id: F6DSM5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS11195
gene id: 696281:DESRU_RS11195
uniprot id: F6DLB3
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01575
gene id: 696281:DESRU_RS01575
uniprot id: F6DPC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS13790
gene id: 696281:DESRU_RS13790
uniprot id: F6DRB5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS04000
gene id: 696281:DESRU_RS04000
uniprot id: F6DUJ8
names: Similarity
messages: Belongs to the P(II) protein family.

696281:DESRU RS02900
gene id: 696281:DESRU_RS02900
uniprot id: F6DSN8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS18610
gene id: 696281:DESRU_RS18610
uniprot id: F6DP66
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS17280
gene id: 696281:DESRU_RS17280
uniprot id: F6DKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS09550
gene id: 696281:DESRU_RS09550
uniprot id: F6DU67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS01840
gene id: 696281:DESRU_RS01840
uniprot id: F6DPH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

696281:DESRU RS15335
gene id: 696281:DESRU_RS15335
uniprot id: F6DTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

696281:DESRU RS11480
gene id: 696281:DESRU_RS11480
uniprot id: F6DLG9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

696281:DESRU RS17900
gene id: 696281:DESRU_RS17900
uniprot id: F6DMJ2
names: Similarity
messages: Belongs to the peptidase S14 family.

696281:DESRU RS14440
gene id: 696281:DESRU_RS14440
uniprot id: F6DSH4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS01545
gene id: 696281:DESRU_RS01545
uniprot id: F6DPB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

696281:DESRU RS14490
gene id: 696281:DESRU_RS14490
uniprot id: F6DSI6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

696281:DESRU RS19305
gene id: 696281:DESRU_RS19305
uniprot id: F6DQP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

696281:DESRU RS19535
gene id: 696281:DESRU_RS19535
uniprot id: F6DRE2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS01425
gene id: 696281:DESRU_RS01425
uniprot id: F6DNN1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

696281:DESRU RS11615
gene id: 696281:DESRU_RS11615
uniprot id: F6DM77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

696281:DESRU RS11110
gene id: 696281:DESRU_RS11110
uniprot id: F6DKS0
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS13380
gene id: 696281:DESRU_RS13380
uniprot id: F6DQH4
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS12600
gene id: 696281:DESRU_RS12600
uniprot id: F6DNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

696281:DESRU RS06635
gene id: 696281:DESRU_RS06635
uniprot id: F6DPJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS15040
gene id: 696281:DESRU_RS15040
uniprot id: F6DT81
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

696281:DESRU RS06375
gene id: 696281:DESRU_RS06375
uniprot id: F6DNS5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

696281:DESRU RS19205
gene id: 696281:DESRU_RS19205
uniprot id: F6DQM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

696281:DESRU RS05215
gene id: 696281:DESRU_RS05215
uniprot id: F6DL76
names: Similarity
messages: Belongs to the transpeptidase family.

696281:DESRU RS17410
gene id: 696281:DESRU_RS17410
uniprot id: F6DLK9
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

696281:DESRU RS06660
gene id: 696281:DESRU_RS06660
uniprot id: F6DPK1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

696281:DESRU RS10180
gene id: 696281:DESRU_RS10180
uniprot id: F6DVA9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

696281:DESRU RS10965
gene id: 696281:DESRU_RS10965
uniprot id: F6DKN9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

696281:DESRU RS17815
gene id: 696281:DESRU_RS17815
uniprot id: F6DMH5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS04580
gene id: 696281:DESRU_RS04580
uniprot id: F6DJW0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

696281:DESRU RS14540
gene id: 696281:DESRU_RS14540
uniprot id: F6DSJ7
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS11365
gene id: 696281:DESRU_RS11365
uniprot id: F6DLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

696281:DESRU RS15835
gene id: 696281:DESRU_RS15835
uniprot id: F6DUU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

696281:DESRU RS06110
gene id: 696281:DESRU_RS06110
uniprot id: F6DN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS00760
gene id: 696281:DESRU_RS00760
uniprot id: F6DMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS13250
gene id: 696281:DESRU_RS13250
uniprot id: F6DQF0
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS15520
gene id: 696281:DESRU_RS15520
uniprot id: F6DU96
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

696281:DESRU RS18420
gene id: 696281:DESRU_RS18420
uniprot id: F6DNG7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

696281:DESRU RS17065
gene id: 696281:DESRU_RS17065
uniprot id: F6DKV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS17115
gene id: 696281:DESRU_RS17115
uniprot id: F6DKW8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

696281:DESRU RS06960
gene id: 696281:DESRU_RS06960
uniprot id: F6DPR2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS16515
gene id: 696281:DESRU_RS16515
uniprot id: F6DVM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

696281:DESRU RS16070
gene id: 696281:DESRU_RS16070
uniprot id: F6DUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS05860
gene id: 696281:DESRU_RS05860
uniprot id: F6DMW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

696281:DESRU RS06950
gene id: 696281:DESRU_RS06950
uniprot id: F6DPR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

696281:DESRU RS11030
gene id: 696281:DESRU_RS11030
uniprot id: F6DKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

696281:DESRU RS06535
gene id: 696281:DESRU_RS06535
uniprot id: F6DNV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

696281:DESRU RS05625
gene id: 696281:DESRU_RS05625
uniprot id: F6DM37
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS07075
gene id: 696281:DESRU_RS07075
uniprot id: F6DQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18980
gene id: 696281:DESRU_RS18980
uniprot id: F6DQ26
names: Similarity
messages: Belongs to the GSP E family.

696281:DESRU RS11945
gene id: 696281:DESRU_RS11945
uniprot id: F6DMD9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

696281:DESRU RS06470
gene id: 696281:DESRU_RS06470
uniprot id: F6DNU4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

696281:DESRU RS16150
gene id: 696281:DESRU_RS16150
uniprot id: F6DV15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS12830
gene id: 696281:DESRU_RS12830
uniprot id: F6DPR7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

696281:DESRU RS01295
gene id: 696281:DESRU_RS01295
uniprot id: F6DNL1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

696281:DESRU RS08285
gene id: 696281:DESRU_RS08285
uniprot id: F6DSB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS10185
gene id: 696281:DESRU_RS10185
uniprot id: F6DVB0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

696281:DESRU RS11955
gene id: 696281:DESRU_RS11955
uniprot id: F6DME1
names: Similarity
messages: Belongs to the HypD family.

696281:DESRU RS04625
gene id: 696281:DESRU_RS04625
uniprot id: F6DJW9
names: Similarity
messages: Belongs to the CobH/CbiC family.

696281:DESRU RS18675
gene id: 696281:DESRU_RS18675
uniprot id: F6DP79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS04930
gene id: 696281:DESRU_RS04930
uniprot id: F6DKI4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

696281:DESRU RS01035
gene id: 696281:DESRU_RS01035
uniprot id: F6DMU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS05655
gene id: 696281:DESRU_RS05655
uniprot id: F6DM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

696281:DESRU RS19560
gene id: 696281:DESRU_RS19560
uniprot id: F6DRE7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS08730
gene id: 696281:DESRU_RS08730
uniprot id: F6DSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

696281:DESRU RS06170
gene id: 696281:DESRU_RS06170
uniprot id: F6DN22
names: Similarity
messages: Belongs to the MotB family.

696281:DESRU RS08430
gene id: 696281:DESRU_RS08430
uniprot id: F6DSD8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS19510
gene id: 696281:DESRU_RS19510
uniprot id: F6DQS9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

696281:DESRU RS19665
gene id: 696281:DESRU_RS19665
uniprot id: F6DQV2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS09840
gene id: 696281:DESRU_RS09840
uniprot id: F6DUQ5
names: Similarity
messages: Belongs to the UPF0234 family.

696281:DESRU RS18140
gene id: 696281:DESRU_RS18140
uniprot id: F6DNB1
names: Similarity
messages: Belongs to the sigma-54 factor family.

696281:DESRU RS19745
gene id: 696281:DESRU_RS19745
uniprot id: F6DV34
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS15195
gene id: 696281:DESRU_RS15195
uniprot id: F6DTP3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

696281:DESRU RS08710
gene id: 696281:DESRU_RS08710
uniprot id: F6DSY0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

696281:DESRU RS07290
gene id: 696281:DESRU_RS07290
uniprot id: F6DQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

696281:DESRU RS00110
gene id: 696281:DESRU_RS00110
uniprot id: F6DL19
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

696281:DESRU RS02740
gene id: 696281:DESRU_RS02740
uniprot id: F6DS64
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

696281:DESRU RS16810
gene id: 696281:DESRU_RS16810
uniprot id: F6DKC1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS18770
gene id: 696281:DESRU_RS18770
uniprot id: F6DP97
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

696281:DESRU RS16820
gene id: 696281:DESRU_RS16820
uniprot id: F6DKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

696281:DESRU RS01380
gene id: 696281:DESRU_RS01380
uniprot id: F6DNM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

696281:DESRU RS15495
gene id: 696281:DESRU_RS15495
uniprot id: F6DU91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS09860
gene id: 696281:DESRU_RS09860
uniprot id: F6DUQ9
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

696281:DESRU RS09500
gene id: 696281:DESRU_RS09500
uniprot id: F6DU57
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS16435
gene id: 696281:DESRU_RS16435
uniprot id: F6DVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

696281:DESRU RS00315
gene id: 696281:DESRU_RS00315
uniprot id: F6DL50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS06285
gene id: 696281:DESRU_RS06285
uniprot id: F6DNQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

696281:DESRU RS16055
gene id: 696281:DESRU_RS16055
uniprot id: F6DUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

696281:DESRU RS11645
gene id: 696281:DESRU_RS11645
uniprot id: F6DM84
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS12010
gene id: 696281:DESRU_RS12010
uniprot id: F6DN30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

696281:DESRU RS15390
gene id: 696281:DESRU_RS15390
uniprot id: F6DTT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

696281:DESRU RS17055
gene id: 696281:DESRU_RS17055
uniprot id: F6DKV5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS10820
gene id: 696281:DESRU_RS10820
uniprot id: F6DKL2
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS02220
gene id: 696281:DESRU_RS02220
uniprot id: F6DRG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS15420
gene id: 696281:DESRU_RS15420
uniprot id: F6DTT7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS15975
gene id: 696281:DESRU_RS15975
uniprot id: F6DUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

696281:DESRU RS13115
gene id: 696281:DESRU_RS13115
uniprot id: F6DPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

696281:DESRU RS05940
gene id: 696281:DESRU_RS05940
uniprot id: F6DMY4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

696281:DESRU RS08055
gene id: 696281:DESRU_RS08055
uniprot id: F6DRT7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS06040
gene id: 696281:DESRU_RS06040
uniprot id: F6DMZ9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

696281:DESRU RS13110
gene id: 696281:DESRU_RS13110
uniprot id: F6DPX4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

696281:DESRU RS00115
gene id: 696281:DESRU_RS00115
uniprot id: F6DL20
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS02980
gene id: 696281:DESRU_RS02980
uniprot id: F6DSQ4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

696281:DESRU RS01895
gene id: 696281:DESRU_RS01895
uniprot id: F6DQT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS02725
gene id: 696281:DESRU_RS02725
uniprot id: F6DS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

696281:DESRU RS04210
gene id: 696281:DESRU_RS04210
uniprot id: F6DV37
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS05265
gene id: 696281:DESRU_RS05265
uniprot id: F6DL86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

696281:DESRU RS16510
gene id: 696281:DESRU_RS16510
uniprot id: F6DVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS13595
gene id: 696281:DESRU_RS13595
uniprot id: F6DR76
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS10565
gene id: 696281:DESRU_RS10565
uniprot id: F6DK27
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS18665
gene id: 696281:DESRU_RS18665
uniprot id: F6DP77
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

696281:DESRU RS06955
gene id: 696281:DESRU_RS06955
uniprot id: F6DPR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

696281:DESRU RS11285
gene id: 696281:DESRU_RS11285
uniprot id: F6DLD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

696281:DESRU RS13225
gene id: 696281:DESRU_RS13225
uniprot id: F6DQE4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

696281:DESRU RS10945
gene id: 696281:DESRU_RS10945
uniprot id: F6DKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

696281:DESRU RS02135
gene id: 696281:DESRU_RS02135
uniprot id: F6DQY2
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS18210
gene id: 696281:DESRU_RS18210
uniprot id: F6DNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

696281:DESRU RS11440
gene id: 696281:DESRU_RS11440
uniprot id: F6DLG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS05065
gene id: 696281:DESRU_RS05065
uniprot id: F6DL51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

696281:DESRU RS08855
gene id: 696281:DESRU_RS08855
uniprot id: F6DT08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

696281:DESRU RS07900
gene id: 696281:DESRU_RS07900
uniprot id: F6DRQ7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

696281:DESRU RS07510
gene id: 696281:DESRU_RS07510
uniprot id: F6DR22
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS01350
gene id: 696281:DESRU_RS01350
uniprot id: F6DNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

696281:DESRU RS12000
gene id: 696281:DESRU_RS12000
uniprot id: F6DN28
names: Similarity
messages: Belongs to the UPF0237 family.

696281:DESRU RS01820
gene id: 696281:DESRU_RS01820
uniprot id: F6DPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

696281:DESRU RS01020
gene id: 696281:DESRU_RS01020
uniprot id: F6DMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

696281:DESRU RS09470
gene id: 696281:DESRU_RS09470
uniprot id: F6DU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

696281:DESRU RS14855
gene id: 696281:DESRU_RS14855
uniprot id: F6DT43
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

696281:DESRU RS07775
gene id: 696281:DESRU_RS07775
uniprot id: F6DRN2
names: Subcellular Location Annotation
messages: Periplasm

696281:DESRU RS09435
gene id: 696281:DESRU_RS09435
uniprot id: F6DU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

696281:DESRU RS07055
gene id: 696281:DESRU_RS07055
uniprot id: F6DQ79
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS07735
gene id: 696281:DESRU_RS07735
uniprot id: F6DR66
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS11585
gene id: 696281:DESRU_RS11585
uniprot id: F6DM71
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS12990
gene id: 696281:DESRU_RS12990
uniprot id: F6DPV0
names: Similarity
messages: Belongs to the UPF0047 family.

696281:DESRU RS13655
gene id: 696281:DESRU_RS13655
uniprot id: F6DR88
names: Similarity
messages: Belongs to the HdrA family.

696281:DESRU RS01875
gene id: 696281:DESRU_RS01875
uniprot id: F6DPI4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

696281:DESRU RS11915
gene id: 696281:DESRU_RS11915
uniprot id: F6DMD3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

696281:DESRU RS16010
gene id: 696281:DESRU_RS16010
uniprot id: F6DUY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

696281:DESRU RS16280
gene id: 696281:DESRU_RS16280
uniprot id: F6DVH5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS03245
gene id: 696281:DESRU_RS03245
uniprot id: F6DTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

696281:DESRU RS13015
gene id: 696281:DESRU_RS13015
uniprot id: F6DPV5
names: Similarity
messages: Belongs to the GerABKA family.

696281:DESRU RS01245
gene id: 696281:DESRU_RS01245
uniprot id: F6DNK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

696281:DESRU RS19260
gene id: 696281:DESRU_RS19260
uniprot id: F6DQN1
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS19520
gene id: 696281:DESRU_RS19520
uniprot id: F6DQT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

696281:DESRU RS02995
gene id: 696281:DESRU_RS02995
uniprot id: F6DSQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS02420
gene id: 696281:DESRU_RS02420
uniprot id: F6DRK8
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

696281:DESRU RS06675
gene id: 696281:DESRU_RS06675
uniprot id: F6DPK4
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

696281:DESRU RS11830
gene id: 696281:DESRU_RS11830
uniprot id: F6DMB7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

696281:DESRU RS15795
gene id: 696281:DESRU_RS15795
uniprot id: F6DUF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS03760
gene id: 696281:DESRU_RS03760
uniprot id: F6DU04
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS10715
gene id: 696281:DESRU_RS10715
uniprot id: F6DK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

696281:DESRU RS18835
gene id: 696281:DESRU_RS18835
uniprot id: F6DPZ6
names: Similarity
messages: Belongs to the CinA family.

696281:DESRU RS18370
gene id: 696281:DESRU_RS18370
uniprot id: F6DNF8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

696281:DESRU RS10955
gene id: 696281:DESRU_RS10955
uniprot id: F6DKN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18705
gene id: 696281:DESRU_RS18705
uniprot id: F6DP84
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

696281:DESRU RS07960
gene id: 696281:DESRU_RS07960
uniprot id: F6DRR9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

696281:DESRU RS03845
gene id: 696281:DESRU_RS03845
uniprot id: F6DUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

696281:DESRU RS09745
gene id: 696281:DESRU_RS09745
uniprot id: F6DUN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS08840
gene id: 696281:DESRU_RS08840
uniprot id: F6DT05
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

696281:DESRU RS05195
gene id: 696281:DESRU_RS05195
uniprot id: F6DL72
names: Similarity
messages: Belongs to the UPF0758 family.

696281:DESRU RS05385
gene id: 696281:DESRU_RS05385
uniprot id: F6DLB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

696281:DESRU RS16535
gene id: 696281:DESRU_RS16535
uniprot id: F6DVM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

696281:DESRU RS08825
gene id: 696281:DESRU_RS08825
uniprot id: F6DT02
names: Similarity
messages: Belongs to the fabD family.

696281:DESRU RS17515
gene id: 696281:DESRU_RS17515
uniprot id: F6DLN0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

696281:DESRU RS08655
gene id: 696281:DESRU_RS08655
uniprot id: F6DSW8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

696281:DESRU RS12020
gene id: 696281:DESRU_RS12020
uniprot id: F6DN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

696281:DESRU RS09675
gene id: 696281:DESRU_RS09675
uniprot id: F6DUM4
names: Similarity
messages: Belongs to the ribF family.

696281:DESRU RS16880
gene id: 696281:DESRU_RS16880
uniprot id: F6DKD6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS05370
gene id: 696281:DESRU_RS05370
uniprot id: F6DLA7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

696281:DESRU RS15145
gene id: 696281:DESRU_RS15145
uniprot id: F6DTN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

696281:DESRU RS10865
gene id: 696281:DESRU_RS10865
uniprot id: F6DKM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

696281:DESRU RS01040
gene id: 696281:DESRU_RS01040
uniprot id: F6DMU4
names: Similarity
messages: Belongs to the peptidase C56 family.

696281:DESRU RS08250
gene id: 696281:DESRU_RS08250
uniprot id: F6DSA7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

696281:DESRU RS10885
gene id: 696281:DESRU_RS10885
uniprot id: F6DKM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

696281:DESRU RS12170
gene id: 696281:DESRU_RS12170
uniprot id: F6DN61
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS17140
gene id: 696281:DESRU_RS17140
uniprot id: F6DKX3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

696281:DESRU RS09910
gene id: 696281:DESRU_RS09910
uniprot id: F6DUR9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS18885
gene id: 696281:DESRU_RS18885
uniprot id: F6DQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

696281:DESRU RS18115
gene id: 696281:DESRU_RS18115
uniprot id: F6DNA6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

696281:DESRU RS19325
gene id: 696281:DESRU_RS19325
uniprot id: F6DQP4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS12665
gene id: 696281:DESRU_RS12665
uniprot id: F6DP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS06540
gene id: 696281:DESRU_RS06540
uniprot id: F6DNV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

696281:DESRU RS04315
gene id: 696281:DESRU_RS04315
uniprot id: F6DV58
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS07170
gene id: 696281:DESRU_RS07170
uniprot id: F6DQA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

696281:DESRU RS12175
gene id: 696281:DESRU_RS12175
uniprot id: F6DN62
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS01300
gene id: 696281:DESRU_RS01300
uniprot id: F6DNL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS07090
gene id: 696281:DESRU_RS07090
uniprot id: F6DQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

696281:DESRU RS10200
gene id: 696281:DESRU_RS10200
uniprot id: F6DVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

696281:DESRU RS06530
gene id: 696281:DESRU_RS06530
uniprot id: F6DNV7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

696281:DESRU RS16445
gene id: 696281:DESRU_RS16445
uniprot id: F6DVK8
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS04230
gene id: 696281:DESRU_RS04230
uniprot id: F6DV40
names: Similarity
messages: Belongs to the glutamate synthase family.

696281:DESRU RS19400
gene id: 696281:DESRU_RS19400
uniprot id: F6DQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS17125
gene id: 696281:DESRU_RS17125
uniprot id: F6DKX0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

696281:DESRU RS03400
gene id: 696281:DESRU_RS03400
uniprot id: F6DTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

696281:DESRU RS15555
gene id: 696281:DESRU_RS15555
uniprot id: F6DUA3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

696281:DESRU RS18160
gene id: 696281:DESRU_RS18160
uniprot id: F6DNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

696281:DESRU RS06350
gene id: 696281:DESRU_RS06350
uniprot id: F6DNS0
names: Subcellular Location Annotation
messages: Cytoplasm

696281:DESRU RS09205
gene id: 696281:DESRU_RS09205
uniprot id: F6DTK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

696281:DESRU RS13695
gene id: 696281:DESRU_RS13695
uniprot id: F6DR96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

696281:DESRU RS17340
gene id: 696281:DESRU_RS17340
uniprot id: F6DLJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

696281:DESRU RS15800
gene id: 696281:DESRU_RS15800
uniprot id: F6DUF2
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS07015
gene id: 696281:DESRU_RS07015
uniprot id: F6DQ71
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

696281:DESRU RS08760
gene id: 696281:DESRU_RS08760
uniprot id: F6DSZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

696281:DESRU RS09790
gene id: 696281:DESRU_RS09790
uniprot id: F6DUP7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

696281:DESRU RS09670
gene id: 696281:DESRU_RS09670
uniprot id: F6DUM3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

696281:DESRU RS18450
gene id: 696281:DESRU_RS18450
uniprot id: F6DP35
names: Subcellular Location Annotation
messages: Periplasm

696281:DESRU RS04330
gene id: 696281:DESRU_RS04330
uniprot id: F6DV60
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

696281:DESRU RS12230
gene id: 696281:DESRU_RS12230
uniprot id: F6DN73
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS16905
gene id: 696281:DESRU_RS16905
uniprot id: F6DKE1
names: Similarity
messages: Belongs to the transpeptidase family.

696281:DESRU RS00255
gene id: 696281:DESRU_RS00255
uniprot id: F6DL40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS11665
gene id: 696281:DESRU_RS11665
uniprot id: F6DM88
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

696281:DESRU RS02760
gene id: 696281:DESRU_RS02760
uniprot id: F6DS68
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

696281:DESRU RS04635
gene id: 696281:DESRU_RS04635
uniprot id: F6DJX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

696281:DESRU RS09105
gene id: 696281:DESRU_RS09105
uniprot id: F6DTI9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

696281:DESRU RS08070
gene id: 696281:DESRU_RS08070
uniprot id: F6DRU0
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS05800
gene id: 696281:DESRU_RS05800
uniprot id: F6DMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

696281:DESRU RS08670
gene id: 696281:DESRU_RS08670
uniprot id: F6DSX1
names: Similarity
messages: Belongs to the UxaA family.

696281:DESRU RS12305
gene id: 696281:DESRU_RS12305
uniprot id: F6DN81
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS15645
gene id: 696281:DESRU_RS15645
uniprot id: F6DUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

696281:DESRU RS03705
gene id: 696281:DESRU_RS03705
uniprot id: F6DTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

696281:DESRU RS15945
gene id: 696281:DESRU_RS15945
uniprot id: F6DUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

696281:DESRU RS11925
gene id: 696281:DESRU_RS11925
uniprot id: F6DMD5
names: Similarity
messages: Belongs to the glutamate synthase family.

696281:DESRU RS11820
gene id: 696281:DESRU_RS11820
uniprot id: F6DMB5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

696281:DESRU RS02285
gene id: 696281:DESRU_RS02285
uniprot id: F6DRI1
names: Similarity
messages: Belongs to the glutamate synthase family.

696281:DESRU RS19445
gene id: 696281:DESRU_RS19445
uniprot id: F6DQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

696281:DESRU RS00805
gene id: 696281:DESRU_RS00805
uniprot id: F6DMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

696281:DESRU RS13745
gene id: 696281:DESRU_RS13745
uniprot id: F6DRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS18480
gene id: 696281:DESRU_RS18480
uniprot id: F6DP40
names: Similarity
messages: Belongs to the ABC transporter superfamily.

696281:DESRU RS10120
gene id: 696281:DESRU_RS10120
uniprot id: F6DV97
names: Similarity
messages: Belongs to the UPF0251 family.

696281:DESRU RS16440
gene id: 696281:DESRU_RS16440
uniprot id: F6DVK7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS16930
gene id: 696281:DESRU_RS16930
uniprot id: F6DKE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS11790
gene id: 696281:DESRU_RS11790
uniprot id: F6DMA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS10515
gene id: 696281:DESRU_RS10515
uniprot id: F6DK17
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

696281:DESRU RS01405
gene id: 696281:DESRU_RS01405
uniprot id: F6DNM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS12785
gene id: 696281:DESRU_RS12785
uniprot id: F6DP29
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

696281:DESRU RS18780
gene id: 696281:DESRU_RS18780
uniprot id: F6DPA0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS18605
gene id: 696281:DESRU_RS18605
uniprot id: F6DP65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

696281:DESRU RS13425
gene id: 696281:DESRU_RS13425
uniprot id: F6DQI3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

696281:DESRU RS01560
gene id: 696281:DESRU_RS01560
uniprot id: F6DPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

696281:DESRU RS07240
gene id: 696281:DESRU_RS07240
uniprot id: F6DQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS17415
gene id: 696281:DESRU_RS17415
uniprot id: F6DLL0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

696281:DESRU RS00610
gene id: 696281:DESRU_RS00610
uniprot id: F6DLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

696281:DESRU RS17345
gene id: 696281:DESRU_RS17345
uniprot id: F6DLJ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

696281:DESRU RS13625
gene id: 696281:DESRU_RS13625
uniprot id: F6DR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

696281:DESRU RS01865
gene id: 696281:DESRU_RS01865
uniprot id: F6DPI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

696281:DESRU RS17420
gene id: 696281:DESRU_RS17420
uniprot id: F6DLL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

696281:DESRU RS01235
gene id: 696281:DESRU_RS01235
uniprot id: F6DNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

696281:DESRU RS06840
gene id: 696281:DESRU_RS06840
uniprot id: F6DPN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

696281:DESRU RS15905
gene id: 696281:DESRU_RS15905
uniprot id: F6DUW2
names: Similarity
messages: Belongs to the transpeptidase family.

696281:DESRU RS19635
gene id: 696281:DESRU_RS19635
uniprot id: F6DRG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

696281:DESRU RS06340
gene id: 696281:DESRU_RS06340
uniprot id: F6DNR8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

696281:DESRU RS12480
gene id: 696281:DESRU_RS12480
uniprot id: F6DNX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

696281:DESRU RS13765
gene id: 696281:DESRU_RS13765
uniprot id: F6DRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS00175
gene id: 696281:DESRU_RS00175
uniprot id: F6DL26
names: Similarity
messages: Belongs to the peptidase S11 family.

696281:DESRU RS12540
gene id: 696281:DESRU_RS12540
uniprot id: F6DNY6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

696281:DESRU RS06215
gene id: 696281:DESRU_RS06215
uniprot id: F6DNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

696281:DESRU RS03050
gene id: 696281:DESRU_RS03050
uniprot id: F6DSR8
names: Similarity
messages: Belongs to the peptidase S11 family.

696281:DESRU RS17275
gene id: 696281:DESRU_RS17275
uniprot id: F6DKZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS06145
gene id: 696281:DESRU_RS06145
uniprot id: F6DN17
names: Similarity
messages: Belongs to the Nudix hydrolase family.

696281:DESRU RS00930
gene id: 696281:DESRU_RS00930
uniprot id: F6DMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

696281:DESRU RS10315
gene id: 696281:DESRU_RS10315
uniprot id: F6DVD7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

696281:DESRU RS17945
gene id: 696281:DESRU_RS17945
uniprot id: F6DMK1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

696281:DESRU RS11340
gene id: 696281:DESRU_RS11340
uniprot id: F6DLE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS07925
gene id: 696281:DESRU_RS07925
uniprot id: F6DRR2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

696281:DESRU RS15745
gene id: 696281:DESRU_RS15745
uniprot id: F6DUE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS00425
gene id: 696281:DESRU_RS00425
uniprot id: F6DLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

696281:DESRU RS19190
gene id: 696281:DESRU_RS19190
uniprot id: F6DQL7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01435
gene id: 696281:DESRU_RS01435
uniprot id: F6DNN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

696281:DESRU RS02325
gene id: 696281:DESRU_RS02325
uniprot id: F6DRI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

696281:DESRU RS18380
gene id: 696281:DESRU_RS18380
uniprot id: F6DNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

696281:DESRU RS15550
gene id: 696281:DESRU_RS15550
uniprot id: F6DUA2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

696281:DESRU RS16915
gene id: 696281:DESRU_RS16915
uniprot id: F6DKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

696281:DESRU RS15150
gene id: 696281:DESRU_RS15150
uniprot id: F6DTN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

696281:DESRU RS16430
gene id: 696281:DESRU_RS16430
uniprot id: F6DVK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

696281:DESRU RS06555
gene id: 696281:DESRU_RS06555
uniprot id: F6DNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

696281:DESRU RS18445
gene id: 696281:DESRU_RS18445
uniprot id: F6DP34
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

696281:DESRU RS19280
gene id: 696281:DESRU_RS19280
uniprot id: F6DQN5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

696281:DESRU RS06520
gene id: 696281:DESRU_RS06520
uniprot id: F6DNV5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

696281:DESRU RS00375
gene id: 696281:DESRU_RS00375
uniprot id: F6DLS7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS18645
gene id: 696281:DESRU_RS18645
uniprot id: F6DP73
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

696281:DESRU RS02175
gene id: 696281:DESRU_RS02175
uniprot id: F6DQZ0
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

696281:DESRU RS17105
gene id: 696281:DESRU_RS17105
uniprot id: F6DKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS08465
gene id: 696281:DESRU_RS08465
uniprot id: F6DSE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

696281:DESRU RS02205
gene id: 696281:DESRU_RS02205
uniprot id: F6DRG6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

696281:DESRU RS09145
gene id: 696281:DESRU_RS09145
uniprot id: F6DTJ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS08600
gene id: 696281:DESRU_RS08600
uniprot id: F6DSV7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

696281:DESRU RS03815
gene id: 696281:DESRU_RS03815
uniprot id: F6DUG5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS18120
gene id: 696281:DESRU_RS18120
uniprot id: F6DNA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

696281:DESRU RS05660
gene id: 696281:DESRU_RS05660
uniprot id: F6DM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

696281:DESRU RS18130
gene id: 696281:DESRU_RS18130
uniprot id: F6DNA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

696281:DESRU RS14885
gene id: 696281:DESRU_RS14885
uniprot id: F6DT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

696281:DESRU RS11190
gene id: 696281:DESRU_RS11190
uniprot id: F6DKT5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

696281:DESRU RS12710
gene id: 696281:DESRU_RS12710
uniprot id: F6DP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS04030
gene id: 696281:DESRU_RS04030
uniprot id: F6DUK4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

696281:DESRU RS19215
gene id: 696281:DESRU_RS19215
uniprot id: F6DQM2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

696281:DESRU RS16035
gene id: 696281:DESRU_RS16035
uniprot id: F6DUZ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS19290
gene id: 696281:DESRU_RS19290
uniprot id: F6DQN7
names: Similarity
messages: Belongs to the TPP enzyme family.

696281:DESRU RS03450
gene id: 696281:DESRU_RS03450
uniprot id: F6DTE4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

696281:DESRU RS06475
gene id: 696281:DESRU_RS06475
uniprot id: F6DNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

696281:DESRU RS09110
gene id: 696281:DESRU_RS09110
uniprot id: F6DTJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

696281:DESRU RS09250
gene id: 696281:DESRU_RS09250
uniprot id: F6DTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

696281:DESRU RS01600
gene id: 696281:DESRU_RS01600
uniprot id: F6DPC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

696281:DESRU RS08545
gene id: 696281:DESRU_RS08545
uniprot id: F6DSU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

696281:DESRU RS06605
gene id: 696281:DESRU_RS06605
uniprot id: F6DPJ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

696281:DESRU RS01570
gene id: 696281:DESRU_RS01570
uniprot id: F6DPC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

696281:DESRU RS04640
gene id: 696281:DESRU_RS04640
uniprot id: F6DJX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

696281:DESRU RS06880
gene id: 696281:DESRU_RS06880
uniprot id: F6DPP6
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

696281:DESRU RS03125
gene id: 696281:DESRU_RS03125
uniprot id: F6DSS9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

696281:DESRU RS12935
gene id: 696281:DESRU_RS12935
uniprot id: F6DPT9
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01785
gene id: 696281:DESRU_RS01785
uniprot id: F6DPG6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

696281:DESRU RS15240
gene id: 696281:DESRU_RS15240
uniprot id: F6DTQ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

696281:DESRU RS06805
gene id: 696281:DESRU_RS06805
uniprot id: F6DPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

696281:DESRU RS16875
gene id: 696281:DESRU_RS16875
uniprot id: F6DKD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS15875
gene id: 696281:DESRU_RS15875
uniprot id: F6DUV6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

696281:DESRU RS18595
gene id: 696281:DESRU_RS18595
uniprot id: F6DP63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

696281:DESRU RS06640
gene id: 696281:DESRU_RS06640
uniprot id: F6DPJ7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

696281:DESRU RS18250
gene id: 696281:DESRU_RS18250
uniprot id: F6DND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

696281:DESRU RS19515
gene id: 696281:DESRU_RS19515
uniprot id: F6DQT0
names: Similarity
messages: Belongs to the peptidase S16 family.

696281:DESRU RS14740
gene id: 696281:DESRU_RS14740
uniprot id: F6DT21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

696281:DESRU RS06570
gene id: 696281:DESRU_RS06570
uniprot id: F6DNW5
names: Similarity
messages: Belongs to the GARS family.

696281:DESRU RS06895
gene id: 696281:DESRU_RS06895
uniprot id: F6DPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

696281:DESRU RS16655
gene id: 696281:DESRU_RS16655
uniprot id: F6DK91
names: Similarity
messages: Belongs to the UPF0235 family.

696281:DESRU RS09875
gene id: 696281:DESRU_RS09875
uniprot id: F6DUR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

696281:DESRU RS02290
gene id: 696281:DESRU_RS02290
uniprot id: F6DRI2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

696281:DESRU RS10450
gene id: 696281:DESRU_RS10450
uniprot id: F6DK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS11380
gene id: 696281:DESRU_RS11380
uniprot id: F6DLF2
names: Similarity
messages: Belongs to the UPF0173 family.

696281:DESRU RS09240
gene id: 696281:DESRU_RS09240
uniprot id: F6DTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

696281:DESRU RS06415
gene id: 696281:DESRU_RS06415
uniprot id: F6DNT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

696281:DESRU RS04860
gene id: 696281:DESRU_RS04860
uniprot id: F6DKG9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

696281:DESRU RS01775
gene id: 696281:DESRU_RS01775
uniprot id: F6DPG4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

696281:DESRU RS06630
gene id: 696281:DESRU_RS06630
uniprot id: F6DPJ5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

696281:DESRU RS02990
gene id: 696281:DESRU_RS02990
uniprot id: F6DSQ6
names: Similarity
messages: Belongs to the TPP enzyme family.

696281:DESRU RS02445
gene id: 696281:DESRU_RS02445
uniprot id: F6DRL3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS07440
gene id: 696281:DESRU_RS07440
uniprot id: F6DR08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

696281:DESRU RS13395
gene id: 696281:DESRU_RS13395
uniprot id: F6DQH7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

696281:DESRU RS16490
gene id: 696281:DESRU_RS16490
uniprot id: F6DVL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS06970
gene id: 696281:DESRU_RS06970
uniprot id: F6DQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

696281:DESRU RS18255
gene id: 696281:DESRU_RS18255
uniprot id: F6DND4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

696281:DESRU RS16485
gene id: 696281:DESRU_RS16485
uniprot id: F6DVL6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

696281:DESRU RS12205
gene id: 696281:DESRU_RS12205
uniprot id: F6DN68
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

696281:DESRU RS15955
gene id: 696281:DESRU_RS15955
uniprot id: F6DUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS05400
gene id: 696281:DESRU_RS05400
uniprot id: F6DLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

696281:DESRU RS11470
gene id: 696281:DESRU_RS11470
uniprot id: F6DLG6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

696281:DESRU RS13390
gene id: 696281:DESRU_RS13390
uniprot id: F6DQH6
names: Similarity
messages: Belongs to the agmatine deiminase family.

696281:DESRU RS18570
gene id: 696281:DESRU_RS18570
uniprot id: F6DP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

696281:DESRU RS13815
gene id: 696281:DESRU_RS13815
uniprot id: F6DRB9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS02970
gene id: 696281:DESRU_RS02970
uniprot id: F6DSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS19360
gene id: 696281:DESRU_RS19360
uniprot id: F6DQQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS03175
gene id: 696281:DESRU_RS03175
uniprot id: F6DT92
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS07065
gene id: 696281:DESRU_RS07065
uniprot id: F6DQ81
names: Similarity
messages: Belongs to the AOR/FOR family.

696281:DESRU RS02615
gene id: 696281:DESRU_RS02615
uniprot id: F6DS39
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

696281:DESRU RS19130
gene id: 696281:DESRU_RS19130
uniprot id: F6DQ58
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS14815
gene id: 696281:DESRU_RS14815
uniprot id: F6DT36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

696281:DESRU RS11345
gene id: 696281:DESRU_RS11345
uniprot id: F6DLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS02910
gene id: 696281:DESRU_RS02910
uniprot id: F6DSP0
names: Similarity
messages: Belongs to the UPF0751 family.

696281:DESRU RS02155
gene id: 696281:DESRU_RS02155
uniprot id: F6DQY6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

696281:DESRU RS19540
gene id: 696281:DESRU_RS19540
uniprot id: F6DRE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

696281:DESRU RS01685
gene id: 696281:DESRU_RS01685
uniprot id: F6DPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

696281:DESRU RS15275
gene id: 696281:DESRU_RS15275
uniprot id: F6DTQ8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

696281:DESRU RS01665
gene id: 696281:DESRU_RS01665
uniprot id: F6DPE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

696281:DESRU RS03770
gene id: 696281:DESRU_RS03770
uniprot id: F6DU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

696281:DESRU RS15485
gene id: 696281:DESRU_RS15485
uniprot id: F6DU89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

696281:DESRU RS16690
gene id: 696281:DESRU_RS16690
uniprot id: F6DK98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

696281:DESRU RS00590
gene id: 696281:DESRU_RS00590
uniprot id: F6DLW9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

696281:DESRU RS16045
gene id: 696281:DESRU_RS16045
uniprot id: F6DUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

696281:DESRU RS16885
gene id: 696281:DESRU_RS16885
uniprot id: F6DKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

696281:DESRU RS11815
gene id: 696281:DESRU_RS11815
uniprot id: F6DMB4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS10045
gene id: 696281:DESRU_RS10045
uniprot id: F6DV82
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

696281:DESRU RS05870
gene id: 696281:DESRU_RS05870
uniprot id: F6DMX0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

696281:DESRU RS13950
gene id: 696281:DESRU_RS13950
uniprot id: F6DRV4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

696281:DESRU RS10375
gene id: 696281:DESRU_RS10375
uniprot id: F6DVE8
names: Similarity
messages: Belongs to the peptidase C40 family.

696281:DESRU RS16390
gene id: 696281:DESRU_RS16390
uniprot id: F6DVJ7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS11780
gene id: 696281:DESRU_RS11780
uniprot id: F6DMA7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

696281:DESRU RS01890
gene id: 696281:DESRU_RS01890
uniprot id: F6DQT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

696281:DESRU RS13130
gene id: 696281:DESRU_RS13130
uniprot id: F6DPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

696281:DESRU RS00510
gene id: 696281:DESRU_RS00510
uniprot id: F6DLV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

696281:DESRU RS05225
gene id: 696281:DESRU_RS05225
uniprot id: F6DL78
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

696281:DESRU RS18135
gene id: 696281:DESRU_RS18135
uniprot id: F6DNB0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

696281:DESRU RS10210
gene id: 696281:DESRU_RS10210
uniprot id: F6DVB6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS01715
gene id: 696281:DESRU_RS01715
uniprot id: F6DPF1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

696281:DESRU RS03855
gene id: 696281:DESRU_RS03855
uniprot id: F6DUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

696281:DESRU RS16115
gene id: 696281:DESRU_RS16115
uniprot id: F6DV08
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS16945
gene id: 696281:DESRU_RS16945
uniprot id: F6DKE9
names: Similarity
messages: Belongs to the Fur family.

696281:DESRU RS08595
gene id: 696281:DESRU_RS08595
uniprot id: F6DSV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS09750
gene id: 696281:DESRU_RS09750
uniprot id: F6DUN9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

696281:DESRU RS07175
gene id: 696281:DESRU_RS07175
uniprot id: F6DQA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

696281:DESRU RS13180
gene id: 696281:DESRU_RS13180
uniprot id: F6DPY9
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

696281:DESRU RS01495
gene id: 696281:DESRU_RS01495
uniprot id: F6DPA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

696281:DESRU RS09535
gene id: 696281:DESRU_RS09535
uniprot id: F6DU64
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

696281:DESRU RS12370
gene id: 696281:DESRU_RS12370
uniprot id: F6DN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS07010
gene id: 696281:DESRU_RS07010
uniprot id: F6DQ70
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

696281:DESRU RS15285
gene id: 696281:DESRU_RS15285
uniprot id: F6DTR0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

696281:DESRU RS02210
gene id: 696281:DESRU_RS02210
uniprot id: F6DRG7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

696281:DESRU RS00410
gene id: 696281:DESRU_RS00410
uniprot id: F6DLT4
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

696281:DESRU RS15570
gene id: 696281:DESRU_RS15570
uniprot id: F6DUA6
names: Similarity
messages: Belongs to the asp23 family.

696281:DESRU RS17315
gene id: 696281:DESRU_RS17315
uniprot id: F6DLI9
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS14820
gene id: 696281:DESRU_RS14820
uniprot id: F6DT37
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

696281:DESRU RS01370
gene id: 696281:DESRU_RS01370
uniprot id: F6DNM0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

696281:DESRU RS17310
gene id: 696281:DESRU_RS17310
uniprot id: F6DKZ8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

696281:DESRU RS04225
gene id: 696281:DESRU_RS04225
uniprot id: F6DV39
names: Similarity
messages: Belongs to the glutamine synthetase family.

696281:DESRU RS06525
gene id: 696281:DESRU_RS06525
uniprot id: F6DNV6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

696281:DESRU RS14750
gene id: 696281:DESRU_RS14750
uniprot id: F6DT23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

696281:DESRU RS05435
gene id: 696281:DESRU_RS05435
uniprot id: F6DLZ8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

696281:DESRU RS11905
gene id: 696281:DESRU_RS11905
uniprot id: F6DMD1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS18455
gene id: 696281:DESRU_RS18455
uniprot id: F6DP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

696281:DESRU RS07835
gene id: 696281:DESRU_RS07835
uniprot id: F6DRP3
names: Similarity
messages: Belongs to the Fur family.

696281:DESRU RS00040
gene id: 696281:DESRU_RS00040
uniprot id: F6DL06
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

696281:DESRU RS15535
gene id: 696281:DESRU_RS15535
uniprot id: F6DU99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

696281:DESRU RS01650
gene id: 696281:DESRU_RS01650
uniprot id: F6DPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

696281:DESRU RS09180
gene id: 696281:DESRU_RS09180
uniprot id: F6DTK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

696281:DESRU RS00020
gene id: 696281:DESRU_RS00020
uniprot id: F6DL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

696281:DESRU RS02580
gene id: 696281:DESRU_RS02580
uniprot id: F6DS32
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

696281:DESRU RS03540
gene id: 696281:DESRU_RS03540
uniprot id: F6DTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

696281:DESRU RS17700
gene id: 696281:DESRU_RS17700
uniprot id: F6DMF2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

696281:DESRU RS02235
gene id: 696281:DESRU_RS02235
uniprot id: F6DRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

696281:DESRU RS11705
gene id: 696281:DESRU_RS11705
uniprot id: F6DM96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

696281:DESRU RS16770
gene id: 696281:DESRU_RS16770
uniprot id: F6DKB4
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

696281:DESRU RS02575
gene id: 696281:DESRU_RS02575
uniprot id: F6DS31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

696281:DESRU RS03915
gene id: 696281:DESRU_RS03915
uniprot id: F6DUI4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

696281:DESRU RS07405
gene id: 696281:DESRU_RS07405
uniprot id: F6DR01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS07600
gene id: 696281:DESRU_RS07600
uniprot id: F6DR40
names: Similarity
messages: Belongs to the pirin family.

696281:DESRU RS00550
gene id: 696281:DESRU_RS00550
uniprot id: F6DLW1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS12840
gene id: 696281:DESRU_RS12840
uniprot id: F6DPS0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

696281:DESRU RS05670
gene id: 696281:DESRU_RS05670
uniprot id: F6DM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

696281:DESRU RS05495
gene id: 696281:DESRU_RS05495
uniprot id: F6DM10
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

696281:DESRU RS03040
gene id: 696281:DESRU_RS03040
uniprot id: F6DSX1
names: Similarity
messages: Belongs to the UxaA family.

696281:DESRU RS08455
gene id: 696281:DESRU_RS08455
uniprot id: F6DSE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS13305
gene id: 696281:DESRU_RS13305
uniprot id: F6DQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS13385
gene id: 696281:DESRU_RS13385
uniprot id: F6DQH5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

696281:DESRU RS14595
gene id: 696281:DESRU_RS14595
uniprot id: F6DSK7
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS16545
gene id: 696281:DESRU_RS16545
uniprot id: F6DVM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

696281:DESRU RS13830
gene id: 696281:DESRU_RS13830
uniprot id: F6DRC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

696281:DESRU RS04415
gene id: 696281:DESRU_RS04415
uniprot id: F6DV76
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS16680
gene id: 696281:DESRU_RS16680
uniprot id: F6DK96
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

696281:DESRU RS12005
gene id: 696281:DESRU_RS12005
uniprot id: F6DN29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

696281:DESRU RS16850
gene id: 696281:DESRU_RS16850
uniprot id: F6DKD0
names: Similarity
messages: Belongs to the UPF0749 family.

696281:DESRU RS19330
gene id: 696281:DESRU_RS19330
uniprot id: F6DQP5
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS00030
gene id: 696281:DESRU_RS00030
uniprot id: F6DL04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

696281:DESRU RS11405
gene id: 696281:DESRU_RS11405
uniprot id: F6DLF7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

696281:DESRU RS09760
gene id: 696281:DESRU_RS09760
uniprot id: F6DUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

696281:DESRU RS02770
gene id: 696281:DESRU_RS02770
uniprot id: F6DS70
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS08050
gene id: 696281:DESRU_RS08050
uniprot id: F6DRT6
names: Subcellular Location Annotation
messages: Membrane

696281:DESRU RS04305
gene id: 696281:DESRU_RS04305
uniprot id: F6DV56
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

696281:DESRU RS02230
gene id: 696281:DESRU_RS02230
uniprot id: F6DRH0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

696281:DESRU RS15220
gene id: 696281:DESRU_RS15220
uniprot id: F6DTP8
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

696281:DESRU RS20065
gene id: 696281:DESRU_RS20065
uniprot id: F6DQ21
names: Similarity
messages: Belongs to the peptidase A24 family.

696281:DESRU RS09870
gene id: 696281:DESRU_RS09870
uniprot id: F6DUR1
names: Similarity
messages: Belongs to the DEAD box helicase family.

696281:DESRU RS15755
gene id: 696281:DESRU_RS15755
uniprot id: F6DUE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

696281:DESRU RS12295
gene id: 696281:DESRU_RS12295
uniprot id: F6DN80
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS15940
gene id: 696281:DESRU_RS15940
uniprot id: F6DUW9
names: Similarity
messages: Belongs to the UPF0473 family.

696281:DESRU RS00105
gene id: 696281:DESRU_RS00105
uniprot id: F6DL18
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

696281:DESRU RS07580
gene id: 696281:DESRU_RS07580
uniprot id: F6DR36
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

696281:DESRU RS16075
gene id: 696281:DESRU_RS16075
uniprot id: F6DUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

696281:DESRU RS03025
gene id: 696281:DESRU_RS03025
uniprot id: F6DSR3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

696281:DESRU RS01710
gene id: 696281:DESRU_RS01710
uniprot id: F6DPF0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

696281:DESRU RS00450
gene id: 696281:DESRU_RS00450
uniprot id: F6DLU2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

696281:DESRU RS09305
gene id: 696281:DESRU_RS09305
uniprot id: F6DU18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

696281:DESRU RS13270
gene id: 696281:DESRU_RS13270
uniprot id: F6DQF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS00325
gene id: 696281:DESRU_RS00325
uniprot id: F6DLR8
names: Similarity
messages: Belongs to the EamA transporter family.

696281:DESRU RS01075
gene id: 696281:DESRU_RS01075
uniprot id: F6DNH6
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

696281:DESRU RS10970
gene id: 696281:DESRU_RS10970
uniprot id: F6DKP0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

696281:DESRU RS03225
gene id: 696281:DESRU_RS03225
uniprot id: F6DTA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

696281:DESRU RS11670
gene id: 696281:DESRU_RS11670
uniprot id: F6DM89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.