692370:A6F68 RS03285
gene id: 692370:A6F68_RS03285
uniprot id: A0A1B2AAJ6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

692370:A6F68 RS12625
gene id: 692370:A6F68_RS12625
uniprot id: A0A1B2AFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

692370:A6F68 RS07005
gene id: 692370:A6F68_RS07005
uniprot id: A0A1B2ACQ9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

692370:A6F68 RS12395
gene id: 692370:A6F68_RS12395
uniprot id: A0A1B2AFY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

692370:A6F68 RS02985
gene id: 692370:A6F68_RS02985
uniprot id: A0A1B2AAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

692370:A6F68 RS03845
gene id: 692370:A6F68_RS03845
uniprot id: A0A1B2AAY7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

692370:A6F68 RS06610
gene id: 692370:A6F68_RS06610
uniprot id: A0A1B2ACH5
names: Similarity
messages: Belongs to the CFA/CMAS family.

692370:A6F68 RS07795
gene id: 692370:A6F68_RS07795
uniprot id: A0A1B2AD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

692370:A6F68 RS10875
gene id: 692370:A6F68_RS10875
uniprot id: A0A1B2AF99
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

692370:A6F68 RS00570
gene id: 692370:A6F68_RS00570
uniprot id: A0A1B2A911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

692370:A6F68 RS13140
gene id: 692370:A6F68_RS13140
uniprot id: A0A1B2AG90
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

692370:A6F68 RS01930
gene id: 692370:A6F68_RS01930
uniprot id: A0A1B2A9T6
names: Similarity
messages: Belongs to the PhzF family.

692370:A6F68 RS07020
gene id: 692370:A6F68_RS07020
uniprot id: A0A1B2ACQ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

692370:A6F68 RS05650
gene id: 692370:A6F68_RS05650
uniprot id: A0A1B2ABX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

692370:A6F68 RS07630
gene id: 692370:A6F68_RS07630
uniprot id: A0A1B2AD28
names: Similarity
messages: Belongs to the YkuD family.

692370:A6F68 RS09890
gene id: 692370:A6F68_RS09890
uniprot id: A0A1B2AEH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

692370:A6F68 RS06290
gene id: 692370:A6F68_RS06290
uniprot id: A0A1B2ACB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

692370:A6F68 RS13245
gene id: 692370:A6F68_RS13245
uniprot id: A0A1B2AGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

692370:A6F68 RS11970
gene id: 692370:A6F68_RS11970
uniprot id: A0A1B2AFW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

692370:A6F68 RS04070
gene id: 692370:A6F68_RS04070
uniprot id: A0A1B2AB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS08560
gene id: 692370:A6F68_RS08560
uniprot id: A0A1B2ADN7
names: Similarity
messages: Belongs to the GST superfamily.

692370:A6F68 RS10530
gene id: 692370:A6F68_RS10530
uniprot id: A0A1B2AEQ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS00380
gene id: 692370:A6F68_RS00380
uniprot id: A0A1B2A904
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS01155
gene id: 692370:A6F68_RS01155
uniprot id: A0A1B2A9N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

692370:A6F68 RS02350
gene id: 692370:A6F68_RS02350
uniprot id: A0A1B2AA34
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

692370:A6F68 RS14550
gene id: 692370:A6F68_RS14550
uniprot id: A0A1B2AH27
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS13545
gene id: 692370:A6F68_RS13545
uniprot id: A0A1B2AGG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

692370:A6F68 RS06340
gene id: 692370:A6F68_RS06340
uniprot id: A0A1B2ACC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

692370:A6F68 RS04045
gene id: 692370:A6F68_RS04045
uniprot id: A0A1B2AB03
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

692370:A6F68 RS00720
gene id: 692370:A6F68_RS00720
uniprot id: A0A1B2A9C1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

692370:A6F68 RS04410
gene id: 692370:A6F68_RS04410
uniprot id: A0A1B2AB64
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS02825
gene id: 692370:A6F68_RS02825
uniprot id: A0A1B2AAB2
names: Similarity
messages: Belongs to the peptidase M24B family.

692370:A6F68 RS00140
gene id: 692370:A6F68_RS00140
uniprot id: A0A1B2A908
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

692370:A6F68 RS05920
gene id: 692370:A6F68_RS05920
uniprot id: A0A1B2ACA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

692370:A6F68 RS00320
gene id: 692370:A6F68_RS00320
uniprot id: A0A1B2A8V6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

692370:A6F68 RS06370
gene id: 692370:A6F68_RS06370
uniprot id: A0A1B2ACC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

692370:A6F68 RS06130
gene id: 692370:A6F68_RS06130
uniprot id: A0A1B2ACD2
names: Similarity
messages: Belongs to the UPF0276 family.

692370:A6F68 RS02870
gene id: 692370:A6F68_RS02870
uniprot id: A0A1B2AAK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

692370:A6F68 RS13300
gene id: 692370:A6F68_RS13300
uniprot id: A0A1B2AGB7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

692370:A6F68 RS02415
gene id: 692370:A6F68_RS02415
uniprot id: A0A1B2AA31
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

692370:A6F68 RS01935
gene id: 692370:A6F68_RS01935
uniprot id: A0A1B2A9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

692370:A6F68 RS11115
gene id: 692370:A6F68_RS11115
uniprot id: A0A1B2AF31
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

692370:A6F68 RS04605
gene id: 692370:A6F68_RS04605
uniprot id: A0A1B2ABH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

692370:A6F68 RS02730
gene id: 692370:A6F68_RS02730
uniprot id: A0A1B2AAF2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

692370:A6F68 RS06035
gene id: 692370:A6F68_RS06035
uniprot id: A0A1B2AC48
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS14430
gene id: 692370:A6F68_RS14430
uniprot id: A0A1B2AGY3
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS09720
gene id: 692370:A6F68_RS09720
uniprot id: A0A1B2AEB7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

692370:A6F68 RS14245
gene id: 692370:A6F68_RS14245
uniprot id: A0A1B2AH33
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

692370:A6F68 RS05435
gene id: 692370:A6F68_RS05435
uniprot id: A0A1B2ABT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

692370:A6F68 RS10100
gene id: 692370:A6F68_RS10100
uniprot id: A0A1B2AEH0
names: Similarity
messages: Belongs to the YkuD family.

692370:A6F68 RS03130
gene id: 692370:A6F68_RS03130
uniprot id: A0A1B2AAG5
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

692370:A6F68 RS14095
gene id: 692370:A6F68_RS14095
uniprot id: A0A1B2AH26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

692370:A6F68 RS02190
gene id: 692370:A6F68_RS02190
uniprot id: A0A1B2A9W3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

692370:A6F68 RS12595
gene id: 692370:A6F68_RS12595
uniprot id: A0A1B2AFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

692370:A6F68 RS05540
gene id: 692370:A6F68_RS05540
uniprot id: A0A1B2AC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

692370:A6F68 RS06470
gene id: 692370:A6F68_RS06470
uniprot id: A0A1B2ACE3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

692370:A6F68 RS03070
gene id: 692370:A6F68_RS03070
uniprot id: A0A1B2AAF6
names: Similarity
messages: Belongs to the peptidase M1 family.

692370:A6F68 RS01035
gene id: 692370:A6F68_RS01035
uniprot id: A0A1B2A9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

692370:A6F68 RS01775
gene id: 692370:A6F68_RS01775
uniprot id: A0A1B2A9Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS06640
gene id: 692370:A6F68_RS06640
uniprot id: A0A1B2ACT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

692370:A6F68 RS04940
gene id: 692370:A6F68_RS04940
uniprot id: A0A1B2ABI4
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

692370:A6F68 RS06390
gene id: 692370:A6F68_RS06390
uniprot id: A0A1B2ACD7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS05525
gene id: 692370:A6F68_RS05525
uniprot id: A0A1B2AC18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS07230
gene id: 692370:A6F68_RS07230
uniprot id: A0A1B2ACV7
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS01470
gene id: 692370:A6F68_RS01470
uniprot id: A0A1B2A9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS12455
gene id: 692370:A6F68_RS12455
uniprot id: A0A1B2AFU7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

692370:A6F68 RS12385
gene id: 692370:A6F68_RS12385
uniprot id: A0A1B2AFU8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

692370:A6F68 RS14000
gene id: 692370:A6F68_RS14000
uniprot id: A0A1B2AGQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS11050
gene id: 692370:A6F68_RS11050
uniprot id: A0A1B2AF55
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

692370:A6F68 RS05620
gene id: 692370:A6F68_RS05620
uniprot id: A0A1B2ABX8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

692370:A6F68 RS13595
gene id: 692370:A6F68_RS13595
uniprot id: A0A1B2AGH4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS00325
gene id: 692370:A6F68_RS00325
uniprot id: A0A1B2A910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

692370:A6F68 RS10470
gene id: 692370:A6F68_RS10470
uniprot id: A0A1B2AF10
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

692370:A6F68 RS11895
gene id: 692370:A6F68_RS11895
uniprot id: A0A1B2AFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

692370:A6F68 RS01175
gene id: 692370:A6F68_RS01175
uniprot id: A0A1B2A9D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

692370:A6F68 RS11845
gene id: 692370:A6F68_RS11845
uniprot id: A0A1B2AFH5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

692370:A6F68 RS07835
gene id: 692370:A6F68_RS07835
uniprot id: A0A1B2AD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

692370:A6F68 RS00950
gene id: 692370:A6F68_RS00950
uniprot id: A0A1B2A9G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

692370:A6F68 RS08905
gene id: 692370:A6F68_RS08905
uniprot id: A0A1B2ADU3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

692370:A6F68 RS07395
gene id: 692370:A6F68_RS07395
uniprot id: A0A1B2AD07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

692370:A6F68 RS08355
gene id: 692370:A6F68_RS08355
uniprot id: A0A1B2ADP1
names: Subunit
messages: Homodimer.

692370:A6F68 RS01610
gene id: 692370:A6F68_RS01610
uniprot id: A0A1B2A9M3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS00195
gene id: 692370:A6F68_RS00195
uniprot id: A0A1B2A937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

692370:A6F68 RS02500
gene id: 692370:A6F68_RS02500
uniprot id: A0A1B2AAG1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

692370:A6F68 RS07455
gene id: 692370:A6F68_RS07455
uniprot id: A0A1B2ACZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

692370:A6F68 RS09700
gene id: 692370:A6F68_RS09700
uniprot id: A0A1B2AEA4
names: Similarity
messages: Belongs to the DNA photolyase family.

692370:A6F68 RS12400
gene id: 692370:A6F68_RS12400
uniprot id: A0A1B2AFT4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

692370:A6F68 RS13770
gene id: 692370:A6F68_RS13770
uniprot id: A0A1B2AGN1
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS02850
gene id: 692370:A6F68_RS02850
uniprot id: A0A1B2AAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

692370:A6F68 RS00415
gene id: 692370:A6F68_RS00415
uniprot id: A0A1B2A8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

692370:A6F68 RS02305
gene id: 692370:A6F68_RS02305
uniprot id: A0A1B2AA08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS11505
gene id: 692370:A6F68_RS11505
uniprot id: A0A1B2AFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

692370:A6F68 RS05905
gene id: 692370:A6F68_RS05905
uniprot id: A0A1B2ACD8
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS10720
gene id: 692370:A6F68_RS10720
uniprot id: A0A1B2AF62
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

692370:A6F68 RS13915
gene id: 692370:A6F68_RS13915
uniprot id: A0A1B2AGP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

692370:A6F68 RS03055
gene id: 692370:A6F68_RS03055
uniprot id: A0A1B2AAM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

692370:A6F68 RS07125
gene id: 692370:A6F68_RS07125
uniprot id: A0A1B2ACS8
names: Similarity
messages: Belongs to the pirin family.

692370:A6F68 RS10330
gene id: 692370:A6F68_RS10330
uniprot id: A0A1B2AEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

692370:A6F68 RS12490
gene id: 692370:A6F68_RS12490
uniprot id: A0A1B2AFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

692370:A6F68 RS08390
gene id: 692370:A6F68_RS08390
uniprot id: A0A1B2ADU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

692370:A6F68 RS06970
gene id: 692370:A6F68_RS06970
uniprot id: A0A1B2ACP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

692370:A6F68 RS07520
gene id: 692370:A6F68_RS07520
uniprot id: A0A1B2AD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

692370:A6F68 RS07880
gene id: 692370:A6F68_RS07880
uniprot id: A0A1B2ADD9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

692370:A6F68 RS02615
gene id: 692370:A6F68_RS02615
uniprot id: A0A1B2AAF3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

692370:A6F68 RS14140
gene id: 692370:A6F68_RS14140
uniprot id: A0A1B2AGS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS10380
gene id: 692370:A6F68_RS10380
uniprot id: A0A1B2AEP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

692370:A6F68 RS06005
gene id: 692370:A6F68_RS06005
uniprot id: A0A1B2AC61
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

692370:A6F68 RS07705
gene id: 692370:A6F68_RS07705
uniprot id: A0A1B2AD54
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

692370:A6F68 RS12350
gene id: 692370:A6F68_RS12350
uniprot id: A0A1B2AFS7
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

692370:A6F68 RS05075
gene id: 692370:A6F68_RS05075
uniprot id: A0A1B2ABN3
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS12575
gene id: 692370:A6F68_RS12575
uniprot id: A0A1B2AFX7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

692370:A6F68 RS03905
gene id: 692370:A6F68_RS03905
uniprot id: A0A1B2AB34
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS02545
gene id: 692370:A6F68_RS02545
uniprot id: A0A1B2AAB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

692370:A6F68 RS10745
gene id: 692370:A6F68_RS10745
uniprot id: A0A1B2AEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

692370:A6F68 RS14255
gene id: 692370:A6F68_RS14255
uniprot id: A0A1B2AGV7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

692370:A6F68 RS01780
gene id: 692370:A6F68_RS01780
uniprot id: A0A1B2A9Q7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

692370:A6F68 RS00085
gene id: 692370:A6F68_RS00085
uniprot id: A0A1B2A8Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

692370:A6F68 RS00765
gene id: 692370:A6F68_RS00765
uniprot id: A0A1B2A940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

692370:A6F68 RS09425
gene id: 692370:A6F68_RS09425
uniprot id: A0A1B2AE41
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

692370:A6F68 RS02410
gene id: 692370:A6F68_RS02410
uniprot id: A0A1B2AAB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS01495
gene id: 692370:A6F68_RS01495
uniprot id: A0A1B2A9H9
names: Function
messages: Acts on leucine, isoleucine and valine.

692370:A6F68 RS08990
gene id: 692370:A6F68_RS08990
uniprot id: A0A1B2ADU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

692370:A6F68 RS03500
gene id: 692370:A6F68_RS03500
uniprot id: A0A1B2AAN2
names: Similarity
messages: Belongs to the peptidase U62 family.

692370:A6F68 RS02555
gene id: 692370:A6F68_RS02555
uniprot id: A0A1B2AA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

692370:A6F68 RS07220
gene id: 692370:A6F68_RS07220
uniprot id: A0A1B2AD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

692370:A6F68 RS09705
gene id: 692370:A6F68_RS09705
uniprot id: A0A1B2AE99
names: Similarity
messages: Belongs to the CFA/CMAS family.

692370:A6F68 RS08875
gene id: 692370:A6F68_RS08875
uniprot id: A0A1B2ADS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

692370:A6F68 RS01075
gene id: 692370:A6F68_RS01075
uniprot id: A0A1B2A9B0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS06090
gene id: 692370:A6F68_RS06090
uniprot id: A0A1B2AC74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS09780
gene id: 692370:A6F68_RS09780
uniprot id: A0A1B2AEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS02650
gene id: 692370:A6F68_RS02650
uniprot id: A0A1B2AAI7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

692370:A6F68 RS04985
gene id: 692370:A6F68_RS04985
uniprot id: A0A1B2ABI3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

692370:A6F68 RS01375
gene id: 692370:A6F68_RS01375
uniprot id: A0A1B2A9H5
names: Similarity
messages: Belongs to the peptidase C40 family.

692370:A6F68 RS02695
gene id: 692370:A6F68_RS02695
uniprot id: A0A1B2AAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

692370:A6F68 RS03645
gene id: 692370:A6F68_RS03645
uniprot id: A0A1B2AAU8
names: Subcellular Location Annotation
messages: Mitochondrion

692370:A6F68 RS14230
gene id: 692370:A6F68_RS14230
uniprot id: A0A1B2AGV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

692370:A6F68 RS02220
gene id: 692370:A6F68_RS02220
uniprot id: A0A1B2A9Z4
names: Similarity
messages: Belongs to the peptidase S9C family.

692370:A6F68 RS07410
gene id: 692370:A6F68_RS07410
uniprot id: A0A1B2ACY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

692370:A6F68 RS01140
gene id: 692370:A6F68_RS01140
uniprot id: A0A1B2A9E9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

692370:A6F68 RS08900
gene id: 692370:A6F68_RS08900
uniprot id: A0A1B2AE49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS04860
gene id: 692370:A6F68_RS04860
uniprot id: A0A1B2ABI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07990
gene id: 692370:A6F68_RS07990
uniprot id: A0A1B2ADC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

692370:A6F68 RS14455
gene id: 692370:A6F68_RS14455
uniprot id: A0A1B2AGY9
names: Similarity
messages: Belongs to the peptidase S9C family.

692370:A6F68 RS06140
gene id: 692370:A6F68_RS06140
uniprot id: A0A1B2AC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS00385
gene id: 692370:A6F68_RS00385
uniprot id: A0A1B2A8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

692370:A6F68 RS11070
gene id: 692370:A6F68_RS11070
uniprot id: A0A1B2AFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS06760
gene id: 692370:A6F68_RS06760
uniprot id: A0A1B2ACK1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

692370:A6F68 RS11880
gene id: 692370:A6F68_RS11880
uniprot id: A0A1B2AFH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS03355
gene id: 692370:A6F68_RS03355
uniprot id: A0A1B2AAS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS11720
gene id: 692370:A6F68_RS11720
uniprot id: A0A1B2AFG5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

692370:A6F68 RS13970
gene id: 692370:A6F68_RS13970
uniprot id: A0A1B2AGQ4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS13165
gene id: 692370:A6F68_RS13165
uniprot id: A0A1B2AG84
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

692370:A6F68 RS08590
gene id: 692370:A6F68_RS08590
uniprot id: A0A1B2ADN5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

692370:A6F68 RS06480
gene id: 692370:A6F68_RS06480
uniprot id: A0A1B2ACK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

692370:A6F68 RS12565
gene id: 692370:A6F68_RS12565
uniprot id: A0A1B2AFW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

692370:A6F68 RS01105
gene id: 692370:A6F68_RS01105
uniprot id: A0A1B2A9M8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

692370:A6F68 RS02000
gene id: 692370:A6F68_RS02000
uniprot id: A0A1B2AA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

692370:A6F68 RS06540
gene id: 692370:A6F68_RS06540
uniprot id: A0A1B2ACK9
names: Similarity
messages: Belongs to the peptidase M13 family.

692370:A6F68 RS07920
gene id: 692370:A6F68_RS07920
uniprot id: A0A1B2AD80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

692370:A6F68 RS02550
gene id: 692370:A6F68_RS02550
uniprot id: A0A1B2AAG9
names: Similarity
messages: Belongs to the CutA family.

692370:A6F68 RS10130
gene id: 692370:A6F68_RS10130
uniprot id: A0A1B2AEI4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS07810
gene id: 692370:A6F68_RS07810
uniprot id: A0A1B2AD87
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

692370:A6F68 RS04880
gene id: 692370:A6F68_RS04880
uniprot id: A0A1B2ABH1
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

692370:A6F68 RS14975
gene id: 692370:A6F68_RS14975
uniprot id: A0A1B2ABN1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

692370:A6F68 RS11170
gene id: 692370:A6F68_RS11170
uniprot id: A0A1B2AF64
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS04635
gene id: 692370:A6F68_RS04635
uniprot id: A0A1B2ABB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

692370:A6F68 RS02960
gene id: 692370:A6F68_RS02960
uniprot id: A0A1B2AAF9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

692370:A6F68 RS06685
gene id: 692370:A6F68_RS06685
uniprot id: A0A1B2ACN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

692370:A6F68 RS07040
gene id: 692370:A6F68_RS07040
uniprot id: A0A1B2ACS5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

692370:A6F68 RS03550
gene id: 692370:A6F68_RS03550
uniprot id: A0A1B2AAP2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

692370:A6F68 RS02025
gene id: 692370:A6F68_RS02025
uniprot id: A0A1B2A9V2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

692370:A6F68 RS07960
gene id: 692370:A6F68_RS07960
uniprot id: A0A1B2ADF7
names: Similarity
messages: Belongs to the peptidase S8 family.

692370:A6F68 RS12535
gene id: 692370:A6F68_RS12535
uniprot id: A0A1B2AFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS12970
gene id: 692370:A6F68_RS12970
uniprot id: A0A1B2AG44
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

692370:A6F68 RS09145
gene id: 692370:A6F68_RS09145
uniprot id: A0A1B2ADZ1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

692370:A6F68 RS12485
gene id: 692370:A6F68_RS12485
uniprot id: A0A1B2AG68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS12210
gene id: 692370:A6F68_RS12210
uniprot id: A0A1B2AFS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

692370:A6F68 RS01390
gene id: 692370:A6F68_RS01390
uniprot id: A0A1B2A9K0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

692370:A6F68 RS11535
gene id: 692370:A6F68_RS11535
uniprot id: A0A1B2AFA5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

692370:A6F68 RS08055
gene id: 692370:A6F68_RS08055
uniprot id: A0A1B2ADD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

692370:A6F68 RS11875
gene id: 692370:A6F68_RS11875
uniprot id: A0A1B2AFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

692370:A6F68 RS06380
gene id: 692370:A6F68_RS06380
uniprot id: A0A1B2ACI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

692370:A6F68 RS03045
gene id: 692370:A6F68_RS03045
uniprot id: A0A1B2AAI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS08820
gene id: 692370:A6F68_RS08820
uniprot id: A0A1B2ADS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

692370:A6F68 RS11590
gene id: 692370:A6F68_RS11590
uniprot id: A0A1B2AFC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS10860
gene id: 692370:A6F68_RS10860
uniprot id: A0A1B2AEW9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS05025
gene id: 692370:A6F68_RS05025
uniprot id: A0A1B2ABS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

692370:A6F68 RS01650
gene id: 692370:A6F68_RS01650
uniprot id: A0A1B2A9U4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS14565
gene id: 692370:A6F68_RS14565
uniprot id: A0A1B2AH28
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

692370:A6F68 RS10340
gene id: 692370:A6F68_RS10340
uniprot id: A0A1B2AET3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS05555
gene id: 692370:A6F68_RS05555
uniprot id: A0A1B2AC25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

692370:A6F68 RS12470
gene id: 692370:A6F68_RS12470
uniprot id: A0A1B2AFU1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

692370:A6F68 RS06825
gene id: 692370:A6F68_RS06825
uniprot id: A0A1B2ACL7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

692370:A6F68 RS00175
gene id: 692370:A6F68_RS00175
uniprot id: A0A1B2A8X9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

692370:A6F68 RS12930
gene id: 692370:A6F68_RS12930
uniprot id: A0A1B2AGG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS09655
gene id: 692370:A6F68_RS09655
uniprot id: A0A1B2AE91
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

692370:A6F68 RS14575
gene id: 692370:A6F68_RS14575
uniprot id: A0A1B2AH06
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

692370:A6F68 RS08185
gene id: 692370:A6F68_RS08185
uniprot id: A0A1B2ADE6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS00345
gene id: 692370:A6F68_RS00345
uniprot id: A0A1B2A971
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

692370:A6F68 RS08780
gene id: 692370:A6F68_RS08780
uniprot id: A0A1B2ADW6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS05470
gene id: 692370:A6F68_RS05470
uniprot id: A0A1B2ABW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

692370:A6F68 RS05915
gene id: 692370:A6F68_RS05915
uniprot id: A0A1B2AC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

692370:A6F68 RS09075
gene id: 692370:A6F68_RS09075
uniprot id: A0A1B2ADW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

692370:A6F68 RS13070
gene id: 692370:A6F68_RS13070
uniprot id: A0A1B2AG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS13455
gene id: 692370:A6F68_RS13455
uniprot id: A0A1B2AGF3
names: Similarity
messages: Belongs to the DEAD box helicase family.

692370:A6F68 RS08015
gene id: 692370:A6F68_RS08015
uniprot id: A0A1B2ADA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

692370:A6F68 RS09905
gene id: 692370:A6F68_RS09905
uniprot id: A0A1B2AEE3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

692370:A6F68 RS06245
gene id: 692370:A6F68_RS06245
uniprot id: A0A1B2ACF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

692370:A6F68 RS05655
gene id: 692370:A6F68_RS05655
uniprot id: A0A1B2ABY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

692370:A6F68 RS11955
gene id: 692370:A6F68_RS11955
uniprot id: A0A1B2AFJ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

692370:A6F68 RS08335
gene id: 692370:A6F68_RS08335
uniprot id: A0A1B2ADJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

692370:A6F68 RS10085
gene id: 692370:A6F68_RS10085
uniprot id: A0A1B2AEH5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

692370:A6F68 RS06730
gene id: 692370:A6F68_RS06730
uniprot id: A0A1B2ACK5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

692370:A6F68 RS10920
gene id: 692370:A6F68_RS10920
uniprot id: A0A1B2AEZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS05000
gene id: 692370:A6F68_RS05000
uniprot id: A0A1B2ABJ2
names: PTM
messages: Binds 1 heme group per subunit.

692370:A6F68 RS09640
gene id: 692370:A6F68_RS09640
uniprot id: A0A1B2AED7
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS00210
gene id: 692370:A6F68_RS00210
uniprot id: A0A1B2A926
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

692370:A6F68 RS06625
gene id: 692370:A6F68_RS06625
uniprot id: A0A1B2ACG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

692370:A6F68 RS11550
gene id: 692370:A6F68_RS11550
uniprot id: A0A1B2AFA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

692370:A6F68 RS10510
gene id: 692370:A6F68_RS10510
uniprot id: A0A1B2AEQ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

692370:A6F68 RS11790
gene id: 692370:A6F68_RS11790
uniprot id: A0A1B2AFG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

692370:A6F68 RS00860
gene id: 692370:A6F68_RS00860
uniprot id: A0A1B2A977
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

692370:A6F68 RS14335
gene id: 692370:A6F68_RS14335
uniprot id: A0A1B2AH01
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS12340
gene id: 692370:A6F68_RS12340
uniprot id: A0A1B2AFR5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS06865
gene id: 692370:A6F68_RS06865
uniprot id: A0A1B2ACT8
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

692370:A6F68 RS08000
gene id: 692370:A6F68_RS08000
uniprot id: A0A1B2ADC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

692370:A6F68 RS06795
gene id: 692370:A6F68_RS06795
uniprot id: A0A1B2ACM2
names: Similarity
messages: Belongs to the DEAD box helicase family.

692370:A6F68 RS12035
gene id: 692370:A6F68_RS12035
uniprot id: A0A1B2AFK8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

692370:A6F68 RS13985
gene id: 692370:A6F68_RS13985
uniprot id: A0A1B2AGP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

692370:A6F68 RS00425
gene id: 692370:A6F68_RS00425
uniprot id: A0A1B2A931
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

692370:A6F68 RS14065
gene id: 692370:A6F68_RS14065
uniprot id: A0A1B2AGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

692370:A6F68 RS07085
gene id: 692370:A6F68_RS07085
uniprot id: A0A1B2AD26
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

692370:A6F68 RS09265
gene id: 692370:A6F68_RS09265
uniprot id: A0A1B2AE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS07130
gene id: 692370:A6F68_RS07130
uniprot id: A0A1B2ACT7
names: Similarity
messages: Belongs to the BolA/IbaG family.

692370:A6F68 RS06945
gene id: 692370:A6F68_RS06945
uniprot id: A0A1B2ACR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

692370:A6F68 RS07495
gene id: 692370:A6F68_RS07495
uniprot id: A0A1B2AD13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

692370:A6F68 RS14145
gene id: 692370:A6F68_RS14145
uniprot id: A0A1B2AGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

692370:A6F68 RS04730
gene id: 692370:A6F68_RS04730
uniprot id: A0A1B2ABF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS11485
gene id: 692370:A6F68_RS11485
uniprot id: A0A1B2AF96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

692370:A6F68 RS11785
gene id: 692370:A6F68_RS11785
uniprot id: A0A1B2AFF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS06435
gene id: 692370:A6F68_RS06435
uniprot id: A0A1B2ACD1
names: Similarity
messages: Belongs to the peptidase S9A family.

692370:A6F68 RS01995
gene id: 692370:A6F68_RS01995
uniprot id: A0A1B2AA15
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

692370:A6F68 RS11320
gene id: 692370:A6F68_RS11320
uniprot id: A0A1B2AFI3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

692370:A6F68 RS10685
gene id: 692370:A6F68_RS10685
uniprot id: A0A1B2AF04
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS08375
gene id: 692370:A6F68_RS08375
uniprot id: A0A1B2ADH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS08035
gene id: 692370:A6F68_RS08035
uniprot id: A0A1B2ADA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

692370:A6F68 RS12745
gene id: 692370:A6F68_RS12745
uniprot id: A0A1B2AG45
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS11705
gene id: 692370:A6F68_RS11705
uniprot id: A0A1B2AFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

692370:A6F68 RS06585
gene id: 692370:A6F68_RS06585
uniprot id: A0A1B2ACL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

692370:A6F68 RS02540
gene id: 692370:A6F68_RS02540
uniprot id: A0A1B2AA33
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

692370:A6F68 RS01005
gene id: 692370:A6F68_RS01005
uniprot id: A0A1B2A9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS12030
gene id: 692370:A6F68_RS12030
uniprot id: A0A1B2AFM5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

692370:A6F68 RS13745
gene id: 692370:A6F68_RS13745
uniprot id: A0A1B2AGK7
names: Similarity
messages: Belongs to the LOG family.

692370:A6F68 RS02420
gene id: 692370:A6F68_RS02420
uniprot id: A0A1B2AA36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

692370:A6F68 RS09620
gene id: 692370:A6F68_RS09620
uniprot id: A0A1B2AE95
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

692370:A6F68 RS01630
gene id: 692370:A6F68_RS01630
uniprot id: A0A1B2A9M7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS03710
gene id: 692370:A6F68_RS03710
uniprot id: A0A1B2AB55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

692370:A6F68 RS11570
gene id: 692370:A6F68_RS11570
uniprot id: A0A1B2AFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

692370:A6F68 RS10450
gene id: 692370:A6F68_RS10450
uniprot id: A0A1B2AEN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

692370:A6F68 RS01700
gene id: 692370:A6F68_RS01700
uniprot id: A0A1B2A9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

692370:A6F68 RS08730
gene id: 692370:A6F68_RS08730
uniprot id: A0A1B2ADV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

692370:A6F68 RS05150
gene id: 692370:A6F68_RS05150
uniprot id: A0A1B2ABM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

692370:A6F68 RS06285
gene id: 692370:A6F68_RS06285
uniprot id: A0A1B2AC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

692370:A6F68 RS13865
gene id: 692370:A6F68_RS13865
uniprot id: A0A1B2AGN3
names: Similarity
messages: Belongs to the HIBADH-related family.

692370:A6F68 RS07340
gene id: 692370:A6F68_RS07340
uniprot id: A0A1B2ACY7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

692370:A6F68 RS07390
gene id: 692370:A6F68_RS07390
uniprot id: A0A1B2ACZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS08440
gene id: 692370:A6F68_RS08440
uniprot id: A0A1B2ADK9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

692370:A6F68 RS02425
gene id: 692370:A6F68_RS02425
uniprot id: A0A1B2AA89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS11525
gene id: 692370:A6F68_RS11525
uniprot id: A0A1B2AFD1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS08720
gene id: 692370:A6F68_RS08720
uniprot id: A0A1B2ADQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

692370:A6F68 RS07595
gene id: 692370:A6F68_RS07595
uniprot id: A0A1B2ADD2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

692370:A6F68 RS13305
gene id: 692370:A6F68_RS13305
uniprot id: A0A1B2AGC4
names: Similarity
messages: Belongs to the arginine deiminase family.

692370:A6F68 RS04915
gene id: 692370:A6F68_RS04915
uniprot id: A0A1B2ABJ8
names: Similarity
messages: Belongs to the virb1 family.

692370:A6F68 RS06100
gene id: 692370:A6F68_RS06100
uniprot id: A0A1B2ACH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS01915
gene id: 692370:A6F68_RS01915
uniprot id: A0A1B2A9T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS09080
gene id: 692370:A6F68_RS09080
uniprot id: A0A1B2ADW5
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

692370:A6F68 RS05645
gene id: 692370:A6F68_RS05645
uniprot id: A0A1B2AC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS04420
gene id: 692370:A6F68_RS04420
uniprot id: A0A1B2ABI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

692370:A6F68 RS06935
gene id: 692370:A6F68_RS06935
uniprot id: A0A1B2ACZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

692370:A6F68 RS01675
gene id: 692370:A6F68_RS01675
uniprot id: A0A1B2A9N7
names: Similarity
messages: Belongs to the glutamate synthase family.

692370:A6F68 RS00810
gene id: 692370:A6F68_RS00810
uniprot id: A0A1B2A967
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

692370:A6F68 RS11095
gene id: 692370:A6F68_RS11095
uniprot id: A0A1B2AF28
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS11205
gene id: 692370:A6F68_RS11205
uniprot id: A0A1B2AF49
names: Similarity
messages: Belongs to the asparagine synthetase family.

692370:A6F68 RS01015
gene id: 692370:A6F68_RS01015
uniprot id: A0A1B2A996
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

692370:A6F68 RS12800
gene id: 692370:A6F68_RS12800
uniprot id: A0A1B2AG16
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS14570
gene id: 692370:A6F68_RS14570
uniprot id: A0A1B2AH13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

692370:A6F68 RS02900
gene id: 692370:A6F68_RS02900
uniprot id: A0A1B2AAJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

692370:A6F68 RS01535
gene id: 692370:A6F68_RS01535
uniprot id: A0A1B2A9Q8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

692370:A6F68 RS01465
gene id: 692370:A6F68_RS01465
uniprot id: A0A1B2A9I5
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS06335
gene id: 692370:A6F68_RS06335
uniprot id: A0A1B2ACB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS08770
gene id: 692370:A6F68_RS08770
uniprot id: A0A1B2ADR4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

692370:A6F68 RS10855
gene id: 692370:A6F68_RS10855
uniprot id: A0A1B2AF16
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

692370:A6F68 RS10900
gene id: 692370:A6F68_RS10900
uniprot id: A0A1B2AEX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS12935
gene id: 692370:A6F68_RS12935
uniprot id: A0A1B2AG47
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

692370:A6F68 RS06430
gene id: 692370:A6F68_RS06430
uniprot id: A0A1B2ACJ6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

692370:A6F68 RS10925
gene id: 692370:A6F68_RS10925
uniprot id: A0A1B2AFB0
names: Similarity
messages: Belongs to the citrate synthase family.

692370:A6F68 RS09590
gene id: 692370:A6F68_RS09590
uniprot id: A0A1B2AEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS13460
gene id: 692370:A6F68_RS13460
uniprot id: A0A1B2AGE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

692370:A6F68 RS00285
gene id: 692370:A6F68_RS00285
uniprot id: A0A1B2A8U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

692370:A6F68 RS09960
gene id: 692370:A6F68_RS09960
uniprot id: A0A1B2AEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

692370:A6F68 RS09795
gene id: 692370:A6F68_RS09795
uniprot id: A0A1B2AEB0
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS09985
gene id: 692370:A6F68_RS09985
uniprot id: A0A1B2AEF1
names: Similarity
messages: Belongs to the group II decarboxylase family.

692370:A6F68 RS12305
gene id: 692370:A6F68_RS12305
uniprot id: A0A1B2AFR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS11225
gene id: 692370:A6F68_RS11225
uniprot id: A0A1B2AF43
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

692370:A6F68 RS01040
gene id: 692370:A6F68_RS01040
uniprot id: A0A1B2A9C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

692370:A6F68 RS09895
gene id: 692370:A6F68_RS09895
uniprot id: A0A1B2AED2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

692370:A6F68 RS00805
gene id: 692370:A6F68_RS00805
uniprot id: A0A1B2A9G5
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

692370:A6F68 RS10505
gene id: 692370:A6F68_RS10505
uniprot id: A0A1B2AET8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

692370:A6F68 RS03770
gene id: 692370:A6F68_RS03770
uniprot id: A0A1B2AAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

692370:A6F68 RS03465
gene id: 692370:A6F68_RS03465
uniprot id: A0A1B2AAQ6
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS05110
gene id: 692370:A6F68_RS05110
uniprot id: A0A1B2ABS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

692370:A6F68 RS11765
gene id: 692370:A6F68_RS11765
uniprot id: A0A1B2AFS8
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS08620
gene id: 692370:A6F68_RS08620
uniprot id: A0A1B2ADN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

692370:A6F68 RS13240
gene id: 692370:A6F68_RS13240
uniprot id: A0A1B2AGE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

692370:A6F68 RS07670
gene id: 692370:A6F68_RS07670
uniprot id: A0A1B2AD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

692370:A6F68 RS04055
gene id: 692370:A6F68_RS04055
uniprot id: A0A1B2AB61
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

692370:A6F68 RS04155
gene id: 692370:A6F68_RS04155
uniprot id: A0A1B2AB87
names: Similarity
messages: Belongs to the IlvD/Edd family.

692370:A6F68 RS10225
gene id: 692370:A6F68_RS10225
uniprot id: A0A1B2AEJ9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

692370:A6F68 RS01735
gene id: 692370:A6F68_RS01735
uniprot id: A0A1B2A9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

692370:A6F68 RS03735
gene id: 692370:A6F68_RS03735
uniprot id: A0A1B2AAU4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

692370:A6F68 RS12140
gene id: 692370:A6F68_RS12140
uniprot id: A0A1B2AFM8
names: Similarity
messages: Belongs to the peptidase S13 family.

692370:A6F68 RS10070
gene id: 692370:A6F68_RS10070
uniprot id: A0A1B2AEH8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

692370:A6F68 RS14385
gene id: 692370:A6F68_RS14385
uniprot id: A0A1B2AH11
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

692370:A6F68 RS14055
gene id: 692370:A6F68_RS14055
uniprot id: A0A1B2AGR5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

692370:A6F68 RS09585
gene id: 692370:A6F68_RS09585
uniprot id: A0A1B2AE63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

692370:A6F68 RS06000
gene id: 692370:A6F68_RS06000
uniprot id: A0A1B2ACF8
names: Subcellular Location Annotation
messages: Cytoplasm

692370:A6F68 RS03830
gene id: 692370:A6F68_RS03830
uniprot id: A0A1B2AAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

692370:A6F68 RS00785
gene id: 692370:A6F68_RS00785
uniprot id: A0A1B2A9A4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

692370:A6F68 RS12645
gene id: 692370:A6F68_RS12645
uniprot id: A0A1B2AG25
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS11930
gene id: 692370:A6F68_RS11930
uniprot id: A0A1B2AFI2
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

692370:A6F68 RS11750
gene id: 692370:A6F68_RS11750
uniprot id: A0A1B2AFF1
names: Similarity
messages: Belongs to the Gfa family.

692370:A6F68 RS13765
gene id: 692370:A6F68_RS13765
uniprot id: A0A1B2AGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS12180
gene id: 692370:A6F68_RS12180
uniprot id: A0A1B2AG08
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

692370:A6F68 RS13920
gene id: 692370:A6F68_RS13920
uniprot id: A0A1B2AGP2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

692370:A6F68 RS11145
gene id: 692370:A6F68_RS11145
uniprot id: A0A1B2AF36
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

692370:A6F68 RS03680
gene id: 692370:A6F68_RS03680
uniprot id: A0A1B2AAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

692370:A6F68 RS01510
gene id: 692370:A6F68_RS01510
uniprot id: A0A1B2A9K6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

692370:A6F68 RS10750
gene id: 692370:A6F68_RS10750
uniprot id: A0A1B2AEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

692370:A6F68 RS01750
gene id: 692370:A6F68_RS01750
uniprot id: A0A1B2A9W5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS06185
gene id: 692370:A6F68_RS06185
uniprot id: A0A1B2AC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

692370:A6F68 RS01955
gene id: 692370:A6F68_RS01955
uniprot id: A0A1B2AA41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

692370:A6F68 RS09320
gene id: 692370:A6F68_RS09320
uniprot id: A0A1B2AE78
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

692370:A6F68 RS03945
gene id: 692370:A6F68_RS03945
uniprot id: A0A1B2AB40
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

692370:A6F68 RS09580
gene id: 692370:A6F68_RS09580
uniprot id: A0A1B2AE71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

692370:A6F68 RS14030
gene id: 692370:A6F68_RS14030
uniprot id: A0A1B2AGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

692370:A6F68 RS01225
gene id: 692370:A6F68_RS01225
uniprot id: A0A1B2A9E1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

692370:A6F68 RS03530
gene id: 692370:A6F68_RS03530
uniprot id: A0A1B2AAP7
names: Similarity
messages: Belongs to the Nth/MutY family.

692370:A6F68 RS11625
gene id: 692370:A6F68_RS11625
uniprot id: A0A1B2AFB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS08670
gene id: 692370:A6F68_RS08670
uniprot id: A0A1B2ADN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

692370:A6F68 RS03765
gene id: 692370:A6F68_RS03765
uniprot id: A0A1B2AAW6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

692370:A6F68 RS14490
gene id: 692370:A6F68_RS14490
uniprot id: A0A1B2AGZ7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

692370:A6F68 RS02865
gene id: 692370:A6F68_RS02865
uniprot id: A0A1B2AAB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

692370:A6F68 RS08095
gene id: 692370:A6F68_RS08095
uniprot id: A0A1B2ADN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

692370:A6F68 RS09880
gene id: 692370:A6F68_RS09880
uniprot id: A0A1B2AEC9
names: Similarity
messages: Belongs to the peptidase S66 family.

692370:A6F68 RS10230
gene id: 692370:A6F68_RS10230
uniprot id: A0A1B2AER3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

692370:A6F68 RS01060
gene id: 692370:A6F68_RS01060
uniprot id: A0A1B2A9B7
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

692370:A6F68 RS05965
gene id: 692370:A6F68_RS05965
uniprot id: A0A1B2ACB0
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS03670
gene id: 692370:A6F68_RS03670
uniprot id: A0A1B2AAS8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

692370:A6F68 RS03400
gene id: 692370:A6F68_RS03400
uniprot id: A0A1B2AAQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

692370:A6F68 RS00310
gene id: 692370:A6F68_RS00310
uniprot id: A0A1B2A944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

692370:A6F68 RS03230
gene id: 692370:A6F68_RS03230
uniprot id: A0A1B2AAR8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

692370:A6F68 RS13540
gene id: 692370:A6F68_RS13540
uniprot id: A0A1B2AGE8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

692370:A6F68 RS11685
gene id: 692370:A6F68_RS11685
uniprot id: A0A1B2AFD9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

692370:A6F68 RS05135
gene id: 692370:A6F68_RS05135
uniprot id: A0A1B2ABL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

692370:A6F68 RS11575
gene id: 692370:A6F68_RS11575
uniprot id: A0A1B2AFA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

692370:A6F68 RS06450
gene id: 692370:A6F68_RS06450
uniprot id: A0A1B2ACP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

692370:A6F68 RS09670
gene id: 692370:A6F68_RS09670
uniprot id: A0A1B2AEA7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

692370:A6F68 RS02715
gene id: 692370:A6F68_RS02715
uniprot id: A0A1B2AAH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

692370:A6F68 RS11645
gene id: 692370:A6F68_RS11645
uniprot id: A0A1B2AFH1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

692370:A6F68 RS04900
gene id: 692370:A6F68_RS04900
uniprot id: A0A1B2ABP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS01460
gene id: 692370:A6F68_RS01460
uniprot id: A0A1B2A9J5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

692370:A6F68 RS04870
gene id: 692370:A6F68_RS04870
uniprot id: A0A1B2ABP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

692370:A6F68 RS08515
gene id: 692370:A6F68_RS08515
uniprot id: A0A1B2ADK8
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

692370:A6F68 RS06485
gene id: 692370:A6F68_RS06485
uniprot id: A0A1B2ACE2
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

692370:A6F68 RS11060
gene id: 692370:A6F68_RS11060
uniprot id: A0A1B2AF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS00050
gene id: 692370:A6F68_RS00050
uniprot id: A0A1B2A8R8
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS03390
gene id: 692370:A6F68_RS03390
uniprot id: A0A1B2AAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS06840
gene id: 692370:A6F68_RS06840
uniprot id: A0A1B2ACX2
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

692370:A6F68 RS08090
gene id: 692370:A6F68_RS08090
uniprot id: A0A1B2ADE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

692370:A6F68 RS05305
gene id: 692370:A6F68_RS05305
uniprot id: A0A1B2ABX4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

692370:A6F68 RS10440
gene id: 692370:A6F68_RS10440
uniprot id: A0A1B2AEU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

692370:A6F68 RS13615
gene id: 692370:A6F68_RS13615
uniprot id: A0A1B2AGL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

692370:A6F68 RS07830
gene id: 692370:A6F68_RS07830
uniprot id: A0A1B2ADC4
names: Similarity
messages: Belongs to the peptidase C56 family.

692370:A6F68 RS03585
gene id: 692370:A6F68_RS03585
uniprot id: A0A1B2AAR0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

692370:A6F68 RS14100
gene id: 692370:A6F68_RS14100
uniprot id: A0A1B2AGS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

692370:A6F68 RS07815
gene id: 692370:A6F68_RS07815
uniprot id: A0A1B2ADC7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

692370:A6F68 RS07570
gene id: 692370:A6F68_RS07570
uniprot id: A0A1B2AD11
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

692370:A6F68 RS11365
gene id: 692370:A6F68_RS11365
uniprot id: A0A1B2AF86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS06560
gene id: 692370:A6F68_RS06560
uniprot id: A0A1B2ACM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

692370:A6F68 RS00920
gene id: 692370:A6F68_RS00920
uniprot id: A0A1B2A9G2
names: Function
messages: Multidrug efflux pump.

692370:A6F68 RS10255
gene id: 692370:A6F68_RS10255
uniprot id: A0A1B2AEK8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

692370:A6F68 RS08320
gene id: 692370:A6F68_RS08320
uniprot id: A0A1B2ADM6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

692370:A6F68 RS04135
gene id: 692370:A6F68_RS04135
uniprot id: A0A1B2AB14
names: Similarity
messages: Belongs to the IlvD/Edd family.

692370:A6F68 RS11805
gene id: 692370:A6F68_RS11805
uniprot id: A0A1B2AFG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

692370:A6F68 RS04665
gene id: 692370:A6F68_RS04665
uniprot id: A0A1B2ABE4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

692370:A6F68 RS03065
gene id: 692370:A6F68_RS03065
uniprot id: A0A1B2AAH8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

692370:A6F68 RS09515
gene id: 692370:A6F68_RS09515
uniprot id: A0A1B2AE69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS08650
gene id: 692370:A6F68_RS08650
uniprot id: A0A1B2ADP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

692370:A6F68 RS12640
gene id: 692370:A6F68_RS12640
uniprot id: A0A1B2AFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

692370:A6F68 RS07015
gene id: 692370:A6F68_RS07015
uniprot id: A0A1B2ACW1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

692370:A6F68 RS11775
gene id: 692370:A6F68_RS11775
uniprot id: A0A1B2AFF0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

692370:A6F68 RS05125
gene id: 692370:A6F68_RS05125
uniprot id: A0A1B2ABU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

692370:A6F68 RS14480
gene id: 692370:A6F68_RS14480
uniprot id: A0A1B2AGZ3
names: Similarity
messages: Belongs to the UPF0174 family.

692370:A6F68 RS01600
gene id: 692370:A6F68_RS01600
uniprot id: A0A1B2A9T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS01070
gene id: 692370:A6F68_RS01070
uniprot id: A0A1B2A9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS09370
gene id: 692370:A6F68_RS09370
uniprot id: A0A1B2AE83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07060
gene id: 692370:A6F68_RS07060
uniprot id: A0A1B2ACR8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

692370:A6F68 RS02470
gene id: 692370:A6F68_RS02470
uniprot id: A0A1B2AA47
names: Similarity
messages: Belongs to the HesB/IscA family.

692370:A6F68 RS07590
gene id: 692370:A6F68_RS07590
uniprot id: A0A1B2AD57
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

692370:A6F68 RS09030
gene id: 692370:A6F68_RS09030
uniprot id: A0A1B2ADV1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

692370:A6F68 RS03815
gene id: 692370:A6F68_RS03815
uniprot id: A0A1B2AAY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

692370:A6F68 RS04115
gene id: 692370:A6F68_RS04115
uniprot id: A0A1B2AB02
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

692370:A6F68 RS09765
gene id: 692370:A6F68_RS09765
uniprot id: A0A1B2AEC2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

692370:A6F68 RS06190
gene id: 692370:A6F68_RS06190
uniprot id: A0A1B2AC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

692370:A6F68 RS11300
gene id: 692370:A6F68_RS11300
uniprot id: A0A1B2AF60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS05725
gene id: 692370:A6F68_RS05725
uniprot id: A0A1B2AC13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

692370:A6F68 RS01940
gene id: 692370:A6F68_RS01940
uniprot id: A0A1B2A9V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

692370:A6F68 RS12495
gene id: 692370:A6F68_RS12495
uniprot id: A0A1B2AG01
names: Similarity
messages: Belongs to the RelE toxin family.

692370:A6F68 RS11640
gene id: 692370:A6F68_RS11640
uniprot id: A0A1B2AFD3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

692370:A6F68 RS05500
gene id: 692370:A6F68_RS05500
uniprot id: A0A1B2ABU8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

692370:A6F68 RS06535
gene id: 692370:A6F68_RS06535
uniprot id: A0A1B2ACG3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

692370:A6F68 RS03150
gene id: 692370:A6F68_RS03150
uniprot id: A0A1B2AAF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

692370:A6F68 RS07430
gene id: 692370:A6F68_RS07430
uniprot id: A0A1B2AD23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

692370:A6F68 RS09270
gene id: 692370:A6F68_RS09270
uniprot id: A0A1B2AE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

692370:A6F68 RS10015
gene id: 692370:A6F68_RS10015
uniprot id: A0A1B2AEG8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

692370:A6F68 RS13550
gene id: 692370:A6F68_RS13550
uniprot id: A0A1B2AGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

692370:A6F68 RS08295
gene id: 692370:A6F68_RS08295
uniprot id: A0A1B2ADS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

692370:A6F68 RS11925
gene id: 692370:A6F68_RS11925
uniprot id: A0A1B2AFK3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

692370:A6F68 RS04955
gene id: 692370:A6F68_RS04955
uniprot id: A0A1B2ABV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS02920
gene id: 692370:A6F68_RS02920
uniprot id: A0A1B2AAL3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

692370:A6F68 RS07265
gene id: 692370:A6F68_RS07265
uniprot id: A0A1B2ACV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

692370:A6F68 RS02140
gene id: 692370:A6F68_RS02140
uniprot id: A0A1B2A9V4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS00850
gene id: 692370:A6F68_RS00850
uniprot id: A0A1B2A9E8
names: Similarity
messages: Belongs to the PRORSD1 family.

692370:A6F68 RS04800
gene id: 692370:A6F68_RS04800
uniprot id: A0A1B2ABE0
names: Similarity
messages: Belongs to the FGGY kinase family.

692370:A6F68 RS03785
gene id: 692370:A6F68_RS03785
uniprot id: A0A1B2AAV4
names: Similarity
messages: Belongs to the pyruvate kinase family.

692370:A6F68 RS09980
gene id: 692370:A6F68_RS09980
uniprot id: A0A1B2AEJ8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

692370:A6F68 RS11460
gene id: 692370:A6F68_RS11460
uniprot id: A0A1B2AFA8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

692370:A6F68 RS06415
gene id: 692370:A6F68_RS06415
uniprot id: A0A1B2ACJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

692370:A6F68 RS12205
gene id: 692370:A6F68_RS12205
uniprot id: A0A1B2AFP9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS03700
gene id: 692370:A6F68_RS03700
uniprot id: A0A1B2AAS2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

692370:A6F68 RS12390
gene id: 692370:A6F68_RS12390
uniprot id: A0A1B2AFS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

692370:A6F68 RS00295
gene id: 692370:A6F68_RS00295
uniprot id: A0A1B2A958
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

692370:A6F68 RS00750
gene id: 692370:A6F68_RS00750
uniprot id: A0A1B2A9C8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

692370:A6F68 RS14305
gene id: 692370:A6F68_RS14305
uniprot id: A0A1B2AH34
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

692370:A6F68 RS01960
gene id: 692370:A6F68_RS01960
uniprot id: A0A1B2A9U9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

692370:A6F68 RS03310
gene id: 692370:A6F68_RS03310
uniprot id: A0A1B2AAW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

692370:A6F68 RS02370
gene id: 692370:A6F68_RS02370
uniprot id: A0A1B2AA25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS06615
gene id: 692370:A6F68_RS06615
uniprot id: A0A1B2ACH2
names: Similarity
messages: Belongs to the CFA/CMAS family.

692370:A6F68 RS02400
gene id: 692370:A6F68_RS02400
uniprot id: A0A1B2AA42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07715
gene id: 692370:A6F68_RS07715
uniprot id: A0A1B2ADA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

692370:A6F68 RS06420
gene id: 692370:A6F68_RS06420
uniprot id: A0A1B2ACD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

692370:A6F68 RS07320
gene id: 692370:A6F68_RS07320
uniprot id: A0A1B2ACW9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

692370:A6F68 RS01045
gene id: 692370:A6F68_RS01045
uniprot id: A0A1B2A992
names: Similarity
messages: Belongs to the peptidase U62 family.

692370:A6F68 RS10715
gene id: 692370:A6F68_RS10715
uniprot id: A0A1B2AEV4
names: Similarity
messages: Belongs to the UPF0166 family.

692370:A6F68 RS06180
gene id: 692370:A6F68_RS06180
uniprot id: A0A1B2ACE0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS09935
gene id: 692370:A6F68_RS09935
uniprot id: A0A1B2AEE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

692370:A6F68 RS11135
gene id: 692370:A6F68_RS11135
uniprot id: A0A1B2AF84
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

692370:A6F68 RS04480
gene id: 692370:A6F68_RS04480
uniprot id: A0A1B2ABG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS02435
gene id: 692370:A6F68_RS02435
uniprot id: A0A1B2AA10
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

692370:A6F68 RS01900
gene id: 692370:A6F68_RS01900
uniprot id: A0A1B2A9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

692370:A6F68 RS09865
gene id: 692370:A6F68_RS09865
uniprot id: A0A1B2AEE1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

692370:A6F68 RS09420
gene id: 692370:A6F68_RS09420
uniprot id: A0A1B2AE90
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

692370:A6F68 RS10430
gene id: 692370:A6F68_RS10430
uniprot id: A0A1B2AEQ9
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

692370:A6F68 RS02565
gene id: 692370:A6F68_RS02565
uniprot id: A0A1B2AAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

692370:A6F68 RS11745
gene id: 692370:A6F68_RS11745
uniprot id: A0A1B2AFJ0
names: Similarity
messages: Belongs to the Gfa family.

692370:A6F68 RS03805
gene id: 692370:A6F68_RS03805
uniprot id: A0A1B2AB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

692370:A6F68 RS08260
gene id: 692370:A6F68_RS08260
uniprot id: A0A1B2ADH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

692370:A6F68 RS02165
gene id: 692370:A6F68_RS02165
uniprot id: A0A1B2AA65
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

692370:A6F68 RS06845
gene id: 692370:A6F68_RS06845
uniprot id: A0A1B2ACN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

692370:A6F68 RS12310
gene id: 692370:A6F68_RS12310
uniprot id: A0A1B2AFV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS08170
gene id: 692370:A6F68_RS08170
uniprot id: A0A1B2ADC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS01980
gene id: 692370:A6F68_RS01980
uniprot id: A0A1B2A9Z9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

692370:A6F68 RS00330
gene id: 692370:A6F68_RS00330
uniprot id: A0A1B2A8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

692370:A6F68 RS04630
gene id: 692370:A6F68_RS04630
uniprot id: A0A1B2ABC8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

692370:A6F68 RS09660
gene id: 692370:A6F68_RS09660
uniprot id: A0A1B2AEK4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS14270
gene id: 692370:A6F68_RS14270
uniprot id: A0A1B2AGW4
names: Subcellular Location Annotation
messages: Cell inner membrane

692370:A6F68 RS04620
gene id: 692370:A6F68_RS04620
uniprot id: A0A1B2ABC7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

692370:A6F68 RS00980
gene id: 692370:A6F68_RS00980
uniprot id: A0A1B2A993
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

692370:A6F68 RS08525
gene id: 692370:A6F68_RS08525
uniprot id: A0A1B2ADR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS05035
gene id: 692370:A6F68_RS05035
uniprot id: A0A1B2ABJ7
names: Similarity
messages: Belongs to the sterol desaturase family.

692370:A6F68 RS07245
gene id: 692370:A6F68_RS07245
uniprot id: A0A1B2ACW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

692370:A6F68 RS06375
gene id: 692370:A6F68_RS06375
uniprot id: A0A1B2ACC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

692370:A6F68 RS01875
gene id: 692370:A6F68_RS01875
uniprot id: A0A1B2A9S4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS10705
gene id: 692370:A6F68_RS10705
uniprot id: A0A1B2AEU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

692370:A6F68 RS05660
gene id: 692370:A6F68_RS05660
uniprot id: A0A1B2AC40
names: Similarity
messages: Belongs to the Tim44 family.

692370:A6F68 RS01405
gene id: 692370:A6F68_RS01405
uniprot id: A0A1B2A9T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

692370:A6F68 RS09245
gene id: 692370:A6F68_RS09245
uniprot id: A0A1B2AE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

692370:A6F68 RS06355
gene id: 692370:A6F68_RS06355
uniprot id: A0A1B2ACC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS08490
gene id: 692370:A6F68_RS08490
uniprot id: A0A1B2ADL8
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS05010
gene id: 692370:A6F68_RS05010
uniprot id: A0A1B2ABW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

692370:A6F68 RS02930
gene id: 692370:A6F68_RS02930
uniprot id: A0A1B2AAC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

692370:A6F68 RS14470
gene id: 692370:A6F68_RS14470
uniprot id: A0A1B2AGZ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

692370:A6F68 RS13975
gene id: 692370:A6F68_RS13975
uniprot id: A0A1B2AGS4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS02495
gene id: 692370:A6F68_RS02495
uniprot id: A0A1B2AAB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

692370:A6F68 RS11090
gene id: 692370:A6F68_RS11090
uniprot id: A0A1B2AF15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS00170
gene id: 692370:A6F68_RS00170
uniprot id: A0A1B2A8T0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

692370:A6F68 RS12460
gene id: 692370:A6F68_RS12460
uniprot id: A0A1B2AFU9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

692370:A6F68 RS05155
gene id: 692370:A6F68_RS05155
uniprot id: A0A1B2ABT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

692370:A6F68 RS05510
gene id: 692370:A6F68_RS05510
uniprot id: A0A1B2AC56
names: Similarity
messages: Belongs to the OmpW/AlkL family.

692370:A6F68 RS03875
gene id: 692370:A6F68_RS03875
uniprot id: A0A1B2AB51
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS11520
gene id: 692370:A6F68_RS11520
uniprot id: A0A1B2AFM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS12500
gene id: 692370:A6F68_RS12500
uniprot id: A0A1B2AFV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

692370:A6F68 RS13995
gene id: 692370:A6F68_RS13995
uniprot id: A0A1B2AH09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS10260
gene id: 692370:A6F68_RS10260
uniprot id: A0A1B2AEL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

692370:A6F68 RS03140
gene id: 692370:A6F68_RS03140
uniprot id: A0A1B2AAM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

692370:A6F68 RS07435
gene id: 692370:A6F68_RS07435
uniprot id: A0A1B2AD97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

692370:A6F68 RS01100
gene id: 692370:A6F68_RS01100
uniprot id: A0A1B2A9J2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

692370:A6F68 RS09855
gene id: 692370:A6F68_RS09855
uniprot id: A0A1B2AED4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

692370:A6F68 RS09305
gene id: 692370:A6F68_RS09305
uniprot id: A0A1B2AEC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS09770
gene id: 692370:A6F68_RS09770
uniprot id: A0A1B2AEC4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS03165
gene id: 692370:A6F68_RS03165
uniprot id: A0A1B2AAJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

692370:A6F68 RS05960
gene id: 692370:A6F68_RS05960
uniprot id: A0A1B2AC59
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS07190
gene id: 692370:A6F68_RS07190
uniprot id: A0A1B2AD44
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

692370:A6F68 RS10250
gene id: 692370:A6F68_RS10250
uniprot id: A0A1B2AEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

692370:A6F68 RS04865
gene id: 692370:A6F68_RS04865
uniprot id: A0A1B2ABJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

692370:A6F68 RS11900
gene id: 692370:A6F68_RS11900
uniprot id: A0A1B2AFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

692370:A6F68 RS12685
gene id: 692370:A6F68_RS12685
uniprot id: A0A1B2AG03
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

692370:A6F68 RS05815
gene id: 692370:A6F68_RS05815
uniprot id: A0A1B2AC19
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

692370:A6F68 RS08500
gene id: 692370:A6F68_RS08500
uniprot id: A0A1B2ADL1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS06395
gene id: 692370:A6F68_RS06395
uniprot id: A0A1B2ACI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS10620
gene id: 692370:A6F68_RS10620
uniprot id: A0A1B2AES9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

692370:A6F68 RS07915
gene id: 692370:A6F68_RS07915
uniprot id: A0A1B2AD83
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

692370:A6F68 RS09240
gene id: 692370:A6F68_RS09240
uniprot id: A0A1B2ADZ6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

692370:A6F68 RS03120
gene id: 692370:A6F68_RS03120
uniprot id: A0A1B2AAH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

692370:A6F68 RS06325
gene id: 692370:A6F68_RS06325
uniprot id: A0A1B2ACB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

692370:A6F68 RS06295
gene id: 692370:A6F68_RS06295
uniprot id: A0A1B2ACF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

692370:A6F68 RS13775
gene id: 692370:A6F68_RS13775
uniprot id: A0A1B2AGL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

692370:A6F68 RS00180
gene id: 692370:A6F68_RS00180
uniprot id: A0A1B2A8W6
names: Similarity
messages: Belongs to the UPF0262 family.

692370:A6F68 RS06875
gene id: 692370:A6F68_RS06875
uniprot id: A0A1B2ACN7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

692370:A6F68 RS06680
gene id: 692370:A6F68_RS06680
uniprot id: A0A1B2ACJ5
names: Similarity
messages: Belongs to the virb1 family.

692370:A6F68 RS10485
gene id: 692370:A6F68_RS10485
uniprot id: A0A1B2AEP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

692370:A6F68 RS07120
gene id: 692370:A6F68_RS07120
uniprot id: A0A1B2ACY3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS08300
gene id: 692370:A6F68_RS08300
uniprot id: A0A1B2ADH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

692370:A6F68 RS05900
gene id: 692370:A6F68_RS05900
uniprot id: A0A1B2AC85
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

692370:A6F68 RS12550
gene id: 692370:A6F68_RS12550
uniprot id: A0A1B2AFW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

692370:A6F68 RS14035
gene id: 692370:A6F68_RS14035
uniprot id: A0A1B2AGQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

692370:A6F68 RS10140
gene id: 692370:A6F68_RS10140
uniprot id: A0A1B2AEG1
names: Cofactor
messages: Can also use Mn(2+) ion.

692370:A6F68 RS09860
gene id: 692370:A6F68_RS09860
uniprot id: A0A1B2AEN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

692370:A6F68 RS12805
gene id: 692370:A6F68_RS12805
uniprot id: A0A1B2AG20
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

692370:A6F68 RS08250
gene id: 692370:A6F68_RS08250
uniprot id: A0A1B2ADR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

692370:A6F68 RS06310
gene id: 692370:A6F68_RS06310
uniprot id: A0A1B2ACD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

692370:A6F68 RS13990
gene id: 692370:A6F68_RS13990
uniprot id: A0A1B2AGQ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS05355
gene id: 692370:A6F68_RS05355
uniprot id: A0A1B2ABY4
names: Similarity
messages: Belongs to the PrpF family.

692370:A6F68 RS03950
gene id: 692370:A6F68_RS03950
uniprot id: A0A1B2AB08
names: Similarity
messages: Belongs to the aldose epimerase family.

692370:A6F68 RS04520
gene id: 692370:A6F68_RS04520
uniprot id: A0A1B2ABB2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS09490
gene id: 692370:A6F68_RS09490
uniprot id: A0A1B2AE45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

692370:A6F68 RS04505
gene id: 692370:A6F68_RS04505
uniprot id: A0A1B2AB85
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

692370:A6F68 RS07380
gene id: 692370:A6F68_RS07380
uniprot id: A0A1B2AD12
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS06315
gene id: 692370:A6F68_RS06315
uniprot id: A0A1B2ACH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

692370:A6F68 RS02365
gene id: 692370:A6F68_RS02365
uniprot id: A0A1B2AA24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

692370:A6F68 RS10700
gene id: 692370:A6F68_RS10700
uniprot id: A0A1B2AEY6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

692370:A6F68 RS09435
gene id: 692370:A6F68_RS09435
uniprot id: A0A1B2AE92
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

692370:A6F68 RS01425
gene id: 692370:A6F68_RS01425
uniprot id: A0A1B2A9I3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

692370:A6F68 RS10355
gene id: 692370:A6F68_RS10355
uniprot id: A0A1B2AER1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS07325
gene id: 692370:A6F68_RS07325
uniprot id: A0A1B2ACX9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS10345
gene id: 692370:A6F68_RS10345
uniprot id: A0A1B2AEM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

692370:A6F68 RS10980
gene id: 692370:A6F68_RS10980
uniprot id: A0A1B2AF23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS13290
gene id: 692370:A6F68_RS13290
uniprot id: A0A1B2AGA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

692370:A6F68 RS12655
gene id: 692370:A6F68_RS12655
uniprot id: A0A1B2AFY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

692370:A6F68 RS08700
gene id: 692370:A6F68_RS08700
uniprot id: A0A1B2AE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

692370:A6F68 RS02710
gene id: 692370:A6F68_RS02710
uniprot id: A0A1B2AA86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

692370:A6F68 RS10275
gene id: 692370:A6F68_RS10275
uniprot id: A0A1B2AEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

692370:A6F68 RS03685
gene id: 692370:A6F68_RS03685
uniprot id: A0A1B2AAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS03115
gene id: 692370:A6F68_RS03115
uniprot id: A0A1B2AAI8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

692370:A6F68 RS09250
gene id: 692370:A6F68_RS09250
uniprot id: A0A1B2AE17
names: Similarity
messages: Belongs to the DprA/Smf family.

692370:A6F68 RS04210
gene id: 692370:A6F68_RS04210
uniprot id: A0A1B2AB25
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

692370:A6F68 RS01990
gene id: 692370:A6F68_RS01990
uniprot id: A0A1B2A9S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

692370:A6F68 RS07710
gene id: 692370:A6F68_RS07710
uniprot id: A0A1B2AD67
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

692370:A6F68 RS13150
gene id: 692370:A6F68_RS13150
uniprot id: A0A1B2AGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

692370:A6F68 RS08005
gene id: 692370:A6F68_RS08005
uniprot id: A0A1B2ADC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

692370:A6F68 RS06490
gene id: 692370:A6F68_RS06490
uniprot id: A0A1B2ACE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

692370:A6F68 RS05790
gene id: 692370:A6F68_RS05790
uniprot id: A0A1B2AC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

692370:A6F68 RS06360
gene id: 692370:A6F68_RS06360
uniprot id: A0A1B2ACD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

692370:A6F68 RS03035
gene id: 692370:A6F68_RS03035
uniprot id: A0A1B2AAK6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

692370:A6F68 RS12965
gene id: 692370:A6F68_RS12965
uniprot id: A0A1B2AG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

692370:A6F68 RS10525
gene id: 692370:A6F68_RS10525
uniprot id: A0A1B2AF24
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

692370:A6F68 RS06320
gene id: 692370:A6F68_RS06320
uniprot id: A0A1B2ACA9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

692370:A6F68 RS00025
gene id: 692370:A6F68_RS00025
uniprot id: A0A1B2A8U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

692370:A6F68 RS00190
gene id: 692370:A6F68_RS00190
uniprot id: A0A1B2A921
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

692370:A6F68 RS10995
gene id: 692370:A6F68_RS10995
uniprot id: A0A1B2AEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS11770
gene id: 692370:A6F68_RS11770
uniprot id: A0A1B2AFH8
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

692370:A6F68 RS10495
gene id: 692370:A6F68_RS10495
uniprot id: A0A1B2AEQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS13475
gene id: 692370:A6F68_RS13475
uniprot id: A0A1B2AGF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

692370:A6F68 RS02755
gene id: 692370:A6F68_RS02755
uniprot id: A0A1B2AAB7
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

692370:A6F68 RS13355
gene id: 692370:A6F68_RS13355
uniprot id: A0A1B2AGF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

692370:A6F68 RS04545
gene id: 692370:A6F68_RS04545
uniprot id: A0A1B2ABG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS10065
gene id: 692370:A6F68_RS10065
uniprot id: A0A1B2AEI1
names: Similarity
messages: Belongs to the transketolase family.

692370:A6F68 RS09375
gene id: 692370:A6F68_RS09375
uniprot id: A0A1B2AE30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS01165
gene id: 692370:A6F68_RS01165
uniprot id: A0A1B2A9C3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

692370:A6F68 RS00740
gene id: 692370:A6F68_RS00740
uniprot id: A0A1B2A968
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

692370:A6F68 RS13660
gene id: 692370:A6F68_RS13660
uniprot id: A0A1B2AGH9
names: Similarity
messages: Belongs to the UPF0178 family.

692370:A6F68 RS06215
gene id: 692370:A6F68_RS06215
uniprot id: A0A1B2ACF5
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

692370:A6F68 RS08755
gene id: 692370:A6F68_RS08755
uniprot id: A0A1B2ADR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

692370:A6F68 RS09090
gene id: 692370:A6F68_RS09090
uniprot id: A0A1B2ADW3
names: Similarity
messages: Belongs to the PhoH family.

692370:A6F68 RS13505
gene id: 692370:A6F68_RS13505
uniprot id: A0A1B2AGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

692370:A6F68 RS08575
gene id: 692370:A6F68_RS08575
uniprot id: A0A1B2ADL3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

692370:A6F68 RS12580
gene id: 692370:A6F68_RS12580
uniprot id: A0A1B2AG91
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

692370:A6F68 RS05140
gene id: 692370:A6F68_RS05140
uniprot id: A0A1B2ABS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS10420
gene id: 692370:A6F68_RS10420
uniprot id: A0A1B2AEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

692370:A6F68 RS08125
gene id: 692370:A6F68_RS08125
uniprot id: A0A1B2ADI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

692370:A6F68 RS14210
gene id: 692370:A6F68_RS14210
uniprot id: A0A1B2AGY2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

692370:A6F68 RS00055
gene id: 692370:A6F68_RS00055
uniprot id: A0A1B2A8Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

692370:A6F68 RS05270
gene id: 692370:A6F68_RS05270
uniprot id: A0A1B2ABS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS10865
gene id: 692370:A6F68_RS10865
uniprot id: A0A1B2AEY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

692370:A6F68 RS03280
gene id: 692370:A6F68_RS03280
uniprot id: A0A1B2AAT0
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

692370:A6F68 RS12105
gene id: 692370:A6F68_RS12105
uniprot id: A0A1B2AFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

692370:A6F68 RS10270
gene id: 692370:A6F68_RS10270
uniprot id: A0A1B2AEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS07305
gene id: 692370:A6F68_RS07305
uniprot id: A0A1B2AD27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

692370:A6F68 RS05695
gene id: 692370:A6F68_RS05695
uniprot id: A0A1B2AC36
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS11615
gene id: 692370:A6F68_RS11615
uniprot id: A0A1B2AFP7
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS09480
gene id: 692370:A6F68_RS09480
uniprot id: A0A1B2AE43
names: Similarity
messages: Belongs to the thioredoxin family.

692370:A6F68 RS04120
gene id: 692370:A6F68_RS04120
uniprot id: A0A1B2AB63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

692370:A6F68 RS08455
gene id: 692370:A6F68_RS08455
uniprot id: A0A1B2ADL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

692370:A6F68 RS02855
gene id: 692370:A6F68_RS02855
uniprot id: A0A1B2AAM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS09740
gene id: 692370:A6F68_RS09740
uniprot id: A0A1B2AEF6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

692370:A6F68 RS07270
gene id: 692370:A6F68_RS07270
uniprot id: A0A1B2AD17
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

692370:A6F68 RS08370
gene id: 692370:A6F68_RS08370
uniprot id: A0A1B2ADN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

692370:A6F68 RS08280
gene id: 692370:A6F68_RS08280
uniprot id: A0A1B2ADF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

692370:A6F68 RS11690
gene id: 692370:A6F68_RS11690
uniprot id: A0A1B2AFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

692370:A6F68 RS03255
gene id: 692370:A6F68_RS03255
uniprot id: A0A1B2AAH6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

692370:A6F68 RS00895
gene id: 692370:A6F68_RS00895
uniprot id: A0A1B2A962
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

692370:A6F68 RS09845
gene id: 692370:A6F68_RS09845
uniprot id: A0A1B2AEC0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

692370:A6F68 RS06305
gene id: 692370:A6F68_RS06305
uniprot id: A0A1B2ACB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS07660
gene id: 692370:A6F68_RS07660
uniprot id: A0A1B2AD94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

692370:A6F68 RS14150
gene id: 692370:A6F68_RS14150
uniprot id: A0A1B2AH29
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

692370:A6F68 RS02660
gene id: 692370:A6F68_RS02660
uniprot id: A0A1B2AA78
names: Similarity
messages: Belongs to the HesB/IscA family.

692370:A6F68 RS01660
gene id: 692370:A6F68_RS01660
uniprot id: A0A1B2A9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

692370:A6F68 RS11480
gene id: 692370:A6F68_RS11480
uniprot id: A0A1B2AFG0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

692370:A6F68 RS08985
gene id: 692370:A6F68_RS08985
uniprot id: A0A1B2AE03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

692370:A6F68 RS03260
gene id: 692370:A6F68_RS03260
uniprot id: A0A1B2AAQ8
names: Similarity
messages: Belongs to the MlaA family.

692370:A6F68 RS13155
gene id: 692370:A6F68_RS13155
uniprot id: A0A1B2AG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

692370:A6F68 RS10650
gene id: 692370:A6F68_RS10650
uniprot id: A0A1B2AEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

692370:A6F68 RS11815
gene id: 692370:A6F68_RS11815
uniprot id: A0A1B2AFT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

692370:A6F68 RS10830
gene id: 692370:A6F68_RS10830
uniprot id: A0A1B2AEV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS06695
gene id: 692370:A6F68_RS06695
uniprot id: A0A1B2ACK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

692370:A6F68 RS05120
gene id: 692370:A6F68_RS05120
uniprot id: A0A1B2ABM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

692370:A6F68 RS03270
gene id: 692370:A6F68_RS03270
uniprot id: A0A1B2AAL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

692370:A6F68 RS07680
gene id: 692370:A6F68_RS07680
uniprot id: A0A1B2AD35
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

692370:A6F68 RS09325
gene id: 692370:A6F68_RS09325
uniprot id: A0A1B2AE15
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS14980
gene id: 692370:A6F68_RS14980
uniprot id: A0A1B2ABT0
names: Similarity
messages: Belongs to the UPF0047 family.

692370:A6F68 RS06115
gene id: 692370:A6F68_RS06115
uniprot id: A0A1B2ACD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

692370:A6F68 RS08505
gene id: 692370:A6F68_RS08505
uniprot id: A0A1B2ADM7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS00185
gene id: 692370:A6F68_RS00185
uniprot id: A0A1B2A8S5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

692370:A6F68 RS06330
gene id: 692370:A6F68_RS06330
uniprot id: A0A1B2ACH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

692370:A6F68 RS11850
gene id: 692370:A6F68_RS11850
uniprot id: A0A1B2AFL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

692370:A6F68 RS00925
gene id: 692370:A6F68_RS00925
uniprot id: A0A1B2A984
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

692370:A6F68 RS13840
gene id: 692370:A6F68_RS13840
uniprot id: A0A1B2AGM4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS12940
gene id: 692370:A6F68_RS12940
uniprot id: A0A1B2AG39
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

692370:A6F68 RS10010
gene id: 692370:A6F68_RS10010
uniprot id: A0A1B2AEG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS00965
gene id: 692370:A6F68_RS00965
uniprot id: A0A1B2A980
names: Similarity
messages: Belongs to the AAA ATPase family.

692370:A6F68 RS02600
gene id: 692370:A6F68_RS02600
uniprot id: A0A1B2AAH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

692370:A6F68 RS03340
gene id: 692370:A6F68_RS03340
uniprot id: A0A1B2AAS3
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

692370:A6F68 RS10460
gene id: 692370:A6F68_RS10460
uniprot id: A0A1B2AEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

692370:A6F68 RS14590
gene id: 692370:A6F68_RS14590
uniprot id: A0A1B2A8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS00695
gene id: 692370:A6F68_RS00695
uniprot id: A0A1B2A9B8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

692370:A6F68 RS14545
gene id: 692370:A6F68_RS14545
uniprot id: A0A1B2AH05
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

692370:A6F68 RS10630
gene id: 692370:A6F68_RS10630
uniprot id: A0A1B2AEV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS07975
gene id: 692370:A6F68_RS07975
uniprot id: A0A1B2ADG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

692370:A6F68 RS04145
gene id: 692370:A6F68_RS04145
uniprot id: A0A1B2AB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

692370:A6F68 RS05910
gene id: 692370:A6F68_RS05910
uniprot id: A0A1B2AC38
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

692370:A6F68 RS07090
gene id: 692370:A6F68_RS07090
uniprot id: A0A1B2ACT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

692370:A6F68 RS04615
gene id: 692370:A6F68_RS04615
uniprot id: A0A1B2ABD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

692370:A6F68 RS01615
gene id: 692370:A6F68_RS01615
uniprot id: A0A1B2A9L4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

692370:A6F68 RS05050
gene id: 692370:A6F68_RS05050
uniprot id: A0A1B2ABQ5
names: Similarity
messages: Belongs to the SufE family.

692370:A6F68 RS09345
gene id: 692370:A6F68_RS09345
uniprot id: A0A1B2AE29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

692370:A6F68 RS12090
gene id: 692370:A6F68_RS12090
uniprot id: A0A1B2AFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

692370:A6F68 RS05720
gene id: 692370:A6F68_RS05720
uniprot id: A0A1B2AC01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

692370:A6F68 RS02020
gene id: 692370:A6F68_RS02020
uniprot id: A0A1B2A9V5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

692370:A6F68 RS07405
gene id: 692370:A6F68_RS07405
uniprot id: A0A1B2ACY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS02300
gene id: 692370:A6F68_RS02300
uniprot id: A0A1B2AA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

692370:A6F68 RS10185
gene id: 692370:A6F68_RS10185
uniprot id: A0A1B2AEI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

692370:A6F68 RS11015
gene id: 692370:A6F68_RS11015
uniprot id: A0A1B2AF07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS02260
gene id: 692370:A6F68_RS02260
uniprot id: A0A1B2AA83
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

692370:A6F68 RS10800
gene id: 692370:A6F68_RS10800
uniprot id: A0A1B2AF05
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

692370:A6F68 RS01000
gene id: 692370:A6F68_RS01000
uniprot id: A0A1B2A9H7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

692370:A6F68 RS10985
gene id: 692370:A6F68_RS10985
uniprot id: A0A1B2AEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

692370:A6F68 RS08285
gene id: 692370:A6F68_RS08285
uniprot id: A0A1B2ADG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

692370:A6F68 RS10910
gene id: 692370:A6F68_RS10910
uniprot id: A0A1B2AEY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

692370:A6F68 RS11335
gene id: 692370:A6F68_RS11335
uniprot id: A0A1B2AFC5
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

692370:A6F68 RS09175
gene id: 692370:A6F68_RS09175
uniprot id: A0A1B2ADY9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

692370:A6F68 RS05715
gene id: 692370:A6F68_RS05715
uniprot id: A0A1B2AC96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

692370:A6F68 RS11840
gene id: 692370:A6F68_RS11840
uniprot id: A0A1B2AFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

692370:A6F68 RS02120
gene id: 692370:A6F68_RS02120
uniprot id: A0A1B2A9X7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

692370:A6F68 RS02175
gene id: 692370:A6F68_RS02175
uniprot id: A0A1B2A9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

692370:A6F68 RS11200
gene id: 692370:A6F68_RS11200
uniprot id: A0A1B2AF40
names: Similarity
messages: Belongs to the pirin family.

692370:A6F68 RS01835
gene id: 692370:A6F68_RS01835
uniprot id: A0A1B2A9X1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS01020
gene id: 692370:A6F68_RS01020
uniprot id: A0A1B2A9I7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

692370:A6F68 RS06805
gene id: 692370:A6F68_RS06805
uniprot id: A0A1B2ACS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

692370:A6F68 RS03110
gene id: 692370:A6F68_RS03110
uniprot id: A0A1B2AAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

692370:A6F68 RS02595
gene id: 692370:A6F68_RS02595
uniprot id: A0A1B2AAD1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

692370:A6F68 RS03060
gene id: 692370:A6F68_RS03060
uniprot id: A0A1B2AAR5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

692370:A6F68 RS11450
gene id: 692370:A6F68_RS11450
uniprot id: A0A1B2AF88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

692370:A6F68 RS07295
gene id: 692370:A6F68_RS07295
uniprot id: A0A1B2ACX5
names: Similarity
messages: Belongs to the peptidase M17 family.

692370:A6F68 RS06300
gene id: 692370:A6F68_RS06300
uniprot id: A0A1B2ACL4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

692370:A6F68 RS00090
gene id: 692370:A6F68_RS00090
uniprot id: A0A1B2A902
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

692370:A6F68 RS05755
gene id: 692370:A6F68_RS05755
uniprot id: A0A1B2AC60
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

692370:A6F68 RS04970
gene id: 692370:A6F68_RS04970
uniprot id: A0A1B2ABL5
names: Similarity
messages: Belongs to the peptidase M16 family.

692370:A6F68 RS09260
gene id: 692370:A6F68_RS09260
uniprot id: A0A1B2AE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

692370:A6F68 RS00100
gene id: 692370:A6F68_RS00100
uniprot id: A0A1B2A8S9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

692370:A6F68 RS03240
gene id: 692370:A6F68_RS03240
uniprot id: A0A1B2AAJ1
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS08045
gene id: 692370:A6F68_RS08045
uniprot id: A0A1B2ADL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS13740
gene id: 692370:A6F68_RS13740
uniprot id: A0A1B2AGV9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

692370:A6F68 RS12650
gene id: 692370:A6F68_RS12650
uniprot id: A0A1B2AFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

692370:A6F68 RS13945
gene id: 692370:A6F68_RS13945
uniprot id: A0A1B2AH00
names: Similarity
messages: Belongs to the peptidase A24 family.

692370:A6F68 RS12275
gene id: 692370:A6F68_RS12275
uniprot id: A0A1B2AFR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS09455
gene id: 692370:A6F68_RS09455
uniprot id: A0A1B2AEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

692370:A6F68 RS11620
gene id: 692370:A6F68_RS11620
uniprot id: A0A1B2AFE7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

692370:A6F68 RS01860
gene id: 692370:A6F68_RS01860
uniprot id: A0A1B2A9S8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

692370:A6F68 RS02160
gene id: 692370:A6F68_RS02160
uniprot id: A0A1B2A9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

692370:A6F68 RS09295
gene id: 692370:A6F68_RS09295
uniprot id: A0A1B2AE21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

692370:A6F68 RS09990
gene id: 692370:A6F68_RS09990
uniprot id: A0A1B2AEF8
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

692370:A6F68 RS07770
gene id: 692370:A6F68_RS07770
uniprot id: A0A1B2AD52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS08255
gene id: 692370:A6F68_RS08255
uniprot id: A0A1B2ADF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

692370:A6F68 RS06675
gene id: 692370:A6F68_RS06675
uniprot id: A0A1B2ACH9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

692370:A6F68 RS00080
gene id: 692370:A6F68_RS00080
uniprot id: A0A1B2A8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

692370:A6F68 RS11680
gene id: 692370:A6F68_RS11680
uniprot id: A0A1B2AFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

692370:A6F68 RS04930
gene id: 692370:A6F68_RS04930
uniprot id: A0A1B2ABH5
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

692370:A6F68 RS03365
gene id: 692370:A6F68_RS03365
uniprot id: A0A1B2AAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

692370:A6F68 RS03620
gene id: 692370:A6F68_RS03620
uniprot id: A0A1B2AAR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS06425
gene id: 692370:A6F68_RS06425
uniprot id: A0A1B2ACD6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

692370:A6F68 RS02945
gene id: 692370:A6F68_RS02945
uniprot id: A0A1B2AAB6
names: Similarity
messages: Belongs to the FBPase class 2 family.

692370:A6F68 RS11435
gene id: 692370:A6F68_RS11435
uniprot id: A0A1B2AF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

692370:A6F68 RS12735
gene id: 692370:A6F68_RS12735
uniprot id: A0A1B2AG13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS10735
gene id: 692370:A6F68_RS10735
uniprot id: A0A1B2AF09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

692370:A6F68 RS12255
gene id: 692370:A6F68_RS12255
uniprot id: A0A1B2AFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

692370:A6F68 RS07475
gene id: 692370:A6F68_RS07475
uniprot id: A0A1B2ACZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

692370:A6F68 RS09200
gene id: 692370:A6F68_RS09200
uniprot id: A0A1B2AE06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS07365
gene id: 692370:A6F68_RS07365
uniprot id: A0A1B2AD37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

692370:A6F68 RS06495
gene id: 692370:A6F68_RS06495
uniprot id: A0A1B2ACJ9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

692370:A6F68 RS09060
gene id: 692370:A6F68_RS09060
uniprot id: A0A1B2ADX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

692370:A6F68 RS13925
gene id: 692370:A6F68_RS13925
uniprot id: A0A1B2AGR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

692370:A6F68 RS07275
gene id: 692370:A6F68_RS07275
uniprot id: A0A1B2ACV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

692370:A6F68 RS06350
gene id: 692370:A6F68_RS06350
uniprot id: A0A1B2ACM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

692370:A6F68 RS02145
gene id: 692370:A6F68_RS02145
uniprot id: A0A1B2AA43
names: Similarity
messages: Belongs to the peptidase S41A family.

692370:A6F68 RS12280
gene id: 692370:A6F68_RS12280
uniprot id: A0A1B2AG24
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

692370:A6F68 RS03750
gene id: 692370:A6F68_RS03750
uniprot id: A0A1B2AAT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS11885
gene id: 692370:A6F68_RS11885
uniprot id: A0A1B2AFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

692370:A6F68 RS09565
gene id: 692370:A6F68_RS09565
uniprot id: A0A1B2AE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

692370:A6F68 RS03405
gene id: 692370:A6F68_RS03405
uniprot id: A0A1B2AAL1
names: Similarity
messages: Belongs to the YggT family.

692370:A6F68 RS05870
gene id: 692370:A6F68_RS05870
uniprot id: A0A1B2AC21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

692370:A6F68 RS11635
gene id: 692370:A6F68_RS11635
uniprot id: A0A1B2AFC8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

692370:A6F68 RS04060
gene id: 692370:A6F68_RS04060
uniprot id: A0A1B2AB33
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

692370:A6F68 RS11010
gene id: 692370:A6F68_RS11010
uniprot id: A0A1B2AF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

692370:A6F68 RS12665
gene id: 692370:A6F68_RS12665
uniprot id: A0A1B2AFY7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS08740
gene id: 692370:A6F68_RS08740
uniprot id: A0A1B2ADQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

692370:A6F68 RS08605
gene id: 692370:A6F68_RS08605
uniprot id: A0A1B2ADM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

692370:A6F68 RS12425
gene id: 692370:A6F68_RS12425
uniprot id: A0A1B2AFU5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

692370:A6F68 RS00335
gene id: 692370:A6F68_RS00335
uniprot id: A0A1B2A8V7
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

692370:A6F68 RS04005
gene id: 692370:A6F68_RS04005
uniprot id: A0A1B2AB54
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

692370:A6F68 RS10565
gene id: 692370:A6F68_RS10565
uniprot id: A0A1B2AER7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

692370:A6F68 RS04815
gene id: 692370:A6F68_RS04815
uniprot id: A0A1B2ABH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

692370:A6F68 RS12680
gene id: 692370:A6F68_RS12680
uniprot id: A0A1B2AGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

692370:A6F68 RS08685
gene id: 692370:A6F68_RS08685
uniprot id: A0A1B2ADN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS00035
gene id: 692370:A6F68_RS00035
uniprot id: A0A1B2A8N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

692370:A6F68 RS13605
gene id: 692370:A6F68_RS13605
uniprot id: A0A1B2AGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

692370:A6F68 RS03410
gene id: 692370:A6F68_RS03410
uniprot id: A0A1B2AAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

692370:A6F68 RS13580
gene id: 692370:A6F68_RS13580
uniprot id: A0A1B2AGJ3
names: Similarity
messages: Belongs to the SELO family.

692370:A6F68 RS07310
gene id: 692370:A6F68_RS07310
uniprot id: A0A1B2ACW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

692370:A6F68 RS03300
gene id: 692370:A6F68_RS03300
uniprot id: A0A1B2AAJ2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

692370:A6F68 RS12380
gene id: 692370:A6F68_RS12380
uniprot id: A0A1B2AG51
names: Similarity
messages: Belongs to the phosphohexose mutase family.

692370:A6F68 RS12545
gene id: 692370:A6F68_RS12545
uniprot id: A0A1B2AG05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

692370:A6F68 RS06345
gene id: 692370:A6F68_RS06345
uniprot id: A0A1B2ACH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

692370:A6F68 RS12375
gene id: 692370:A6F68_RS12375
uniprot id: A0A1B2AFT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

692370:A6F68 RS02360
gene id: 692370:A6F68_RS02360
uniprot id: A0A1B2AAA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

692370:A6F68 RS14045
gene id: 692370:A6F68_RS14045
uniprot id: A0A1B2AH23
names: Similarity
messages: Belongs to the peptidase M16 family.

692370:A6F68 RS08910
gene id: 692370:A6F68_RS08910
uniprot id: A0A1B2ADV3
names: Similarity
messages: Belongs to the TPP enzyme family.

692370:A6F68 RS15020
gene id: 692370:A6F68_RS15020
uniprot id: A0A1B2ADT8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

692370:A6F68 RS10080
gene id: 692370:A6F68_RS10080
uniprot id: A0A1B2AEP0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

692370:A6F68 RS12860
gene id: 692370:A6F68_RS12860
uniprot id: A0A1B2AG48
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

692370:A6F68 RS07385
gene id: 692370:A6F68_RS07385
uniprot id: A0A1B2AD86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS15290
gene id: 692370:A6F68_RS15290
uniprot id: A0A1B2A9T2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

692370:A6F68 RS13610
gene id: 692370:A6F68_RS13610
uniprot id: A0A1B2AGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

692370:A6F68 RS08325
gene id: 692370:A6F68_RS08325
uniprot id: A0A1B2ADG4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS11290
gene id: 692370:A6F68_RS11290
uniprot id: A0A1B2AF65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07425
gene id: 692370:A6F68_RS07425
uniprot id: A0A1B2AD00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

692370:A6F68 RS07750
gene id: 692370:A6F68_RS07750
uniprot id: A0A1B2ADG1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

692370:A6F68 RS11455
gene id: 692370:A6F68_RS11455
uniprot id: A0A1B2AF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

692370:A6F68 RS12660
gene id: 692370:A6F68_RS12660
uniprot id: A0A1B2AG12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

692370:A6F68 RS10890
gene id: 692370:A6F68_RS10890
uniprot id: A0A1B2AF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

692370:A6F68 RS08825
gene id: 692370:A6F68_RS08825
uniprot id: A0A1B2ADR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

692370:A6F68 RS12300
gene id: 692370:A6F68_RS12300
uniprot id: A0A1B2AFR9
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

692370:A6F68 RS13705
gene id: 692370:A6F68_RS13705
uniprot id: A0A1B2AGN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

692370:A6F68 RS02045
gene id: 692370:A6F68_RS02045
uniprot id: A0A1B2AA28
names: Similarity
messages: Belongs to the HisA/HisF family.

692370:A6F68 RS06580
gene id: 692370:A6F68_RS06580
uniprot id: A0A1B2ACH4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

692370:A6F68 RS13555
gene id: 692370:A6F68_RS13555
uniprot id: A0A1B2AGG9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

692370:A6F68 RS00935
gene id: 692370:A6F68_RS00935
uniprot id: A0A1B2A9D4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

692370:A6F68 RS08915
gene id: 692370:A6F68_RS08915
uniprot id: A0A1B2AE00
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

692370:A6F68 RS09535
gene id: 692370:A6F68_RS09535
uniprot id: A0A1B2AE53
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

692370:A6F68 RS06405
gene id: 692370:A6F68_RS06405
uniprot id: A0A1B2ACE1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

692370:A6F68 RS00545
gene id: 692370:A6F68_RS00545
uniprot id: A0A1B2A9B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

692370:A6F68 RS09110
gene id: 692370:A6F68_RS09110
uniprot id: A0A1B2ADY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS13175
gene id: 692370:A6F68_RS13175
uniprot id: A0A1B2AGK8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

692370:A6F68 RS00540
gene id: 692370:A6F68_RS00540
uniprot id: A0A1B2A989
names: Similarity
messages: Belongs to the IlvD/Edd family.

692370:A6F68 RS07290
gene id: 692370:A6F68_RS07290
uniprot id: A0A1B2AD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

692370:A6F68 RS00135
gene id: 692370:A6F68_RS00135
uniprot id: A0A1B2A8R6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

692370:A6F68 RS03660
gene id: 692370:A6F68_RS03660
uniprot id: A0A1B2AB42
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

692370:A6F68 RS10500
gene id: 692370:A6F68_RS10500
uniprot id: A0A1B2AEP8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

692370:A6F68 RS12830
gene id: 692370:A6F68_RS12830
uniprot id: A0A1B2AGE0
names: Similarity
messages: Belongs to the PrpD family.

692370:A6F68 RS10970
gene id: 692370:A6F68_RS10970
uniprot id: A0A1B2AF00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS11255
gene id: 692370:A6F68_RS11255
uniprot id: A0A1B2AF59
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

692370:A6F68 RS02895
gene id: 692370:A6F68_RS02895
uniprot id: A0A1B2AAA8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

692370:A6F68 RS13880
gene id: 692370:A6F68_RS13880
uniprot id: A0A1B2AGM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

692370:A6F68 RS08830
gene id: 692370:A6F68_RS08830
uniprot id: A0A1B2ADX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

692370:A6F68 RS13870
gene id: 692370:A6F68_RS13870
uniprot id: A0A1B2AGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

692370:A6F68 RS11155
gene id: 692370:A6F68_RS11155
uniprot id: A0A1B2AF32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

692370:A6F68 RS08995
gene id: 692370:A6F68_RS08995
uniprot id: A0A1B2ADW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

692370:A6F68 RS03170
gene id: 692370:A6F68_RS03170
uniprot id: A0A1B2AAI2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

692370:A6F68 RS06525
gene id: 692370:A6F68_RS06525
uniprot id: A0A1B2ACL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

692370:A6F68 RS07625
gene id: 692370:A6F68_RS07625
uniprot id: A0A1B2AD88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

692370:A6F68 RS05485
gene id: 692370:A6F68_RS05485
uniprot id: A0A1B2ABU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

692370:A6F68 RS10145
gene id: 692370:A6F68_RS10145
uniprot id: A0A1B2AEM4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

692370:A6F68 RS09975
gene id: 692370:A6F68_RS09975
uniprot id: A0A1B2AED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

692370:A6F68 RS10795
gene id: 692370:A6F68_RS10795
uniprot id: A0A1B2AEV7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

692370:A6F68 RS04950
gene id: 692370:A6F68_RS04950
uniprot id: A0A1B2ABP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm
messages: Part of the Type IV secretion system.

692370:A6F68 RS00315
gene id: 692370:A6F68_RS00315
uniprot id: A0A1B2A8V4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

692370:A6F68 RS03600
gene id: 692370:A6F68_RS03600
uniprot id: A0A1B2AAQ1
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS01720
gene id: 692370:A6F68_RS01720
uniprot id: A0A1B2A9X2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

692370:A6F68 RS14440
gene id: 692370:A6F68_RS14440
uniprot id: A0A1B2AGY6
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS05460
gene id: 692370:A6F68_RS05460
uniprot id: A0A1B2AC04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS12125
gene id: 692370:A6F68_RS12125
uniprot id: A0A1B2AFN2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

692370:A6F68 RS13295
gene id: 692370:A6F68_RS13295
uniprot id: A0A1B2AGF4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

692370:A6F68 RS09840
gene id: 692370:A6F68_RS09840
uniprot id: A0A1B2AEH7
names: Similarity
messages: Belongs to the UPF0102 family.

692370:A6F68 RS00075
gene id: 692370:A6F68_RS00075
uniprot id: A0A1B2A8V5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

692370:A6F68 RS11330
gene id: 692370:A6F68_RS11330
uniprot id: A0A1B2AF61
names: Similarity
messages: Belongs to the virb1 family.

692370:A6F68 RS08810
gene id: 692370:A6F68_RS08810
uniprot id: A0A1B2ADT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

692370:A6F68 RS07965
gene id: 692370:A6F68_RS07965
uniprot id: A0A1B2AD93
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

692370:A6F68 RS10990
gene id: 692370:A6F68_RS10990
uniprot id: A0A1B2AF57
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

692370:A6F68 RS02280
gene id: 692370:A6F68_RS02280
uniprot id: A0A1B2AA35
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

692370:A6F68 RS14220
gene id: 692370:A6F68_RS14220
uniprot id: A0A1B2AGV3
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

692370:A6F68 RS14040
gene id: 692370:A6F68_RS14040
uniprot id: A0A1B2AGR7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

692370:A6F68 RS04515
gene id: 692370:A6F68_RS04515
uniprot id: A0A1B2ABK3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

692370:A6F68 RS04015
gene id: 692370:A6F68_RS04015
uniprot id: A0A1B2AAY4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

692370:A6F68 RS14160
gene id: 692370:A6F68_RS14160
uniprot id: A0A1B2AGT7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

692370:A6F68 RS08205
gene id: 692370:A6F68_RS08205
uniprot id: A0A1B2ADG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

692370:A6F68 RS08815
gene id: 692370:A6F68_RS08815
uniprot id: A0A1B2ADY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

692370:A6F68 RS13875
gene id: 692370:A6F68_RS13875
uniprot id: A0A1B2AGQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

692370:A6F68 RS01420
gene id: 692370:A6F68_RS01420
uniprot id: A0A1B2A9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

692370:A6F68 RS06400
gene id: 692370:A6F68_RS06400
uniprot id: A0A1B2ACN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

692370:A6F68 RS07420
gene id: 692370:A6F68_RS07420
uniprot id: A0A1B2ACY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

692370:A6F68 RS02990
gene id: 692370:A6F68_RS02990
uniprot id: A0A1B2AAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

692370:A6F68 RS10415
gene id: 692370:A6F68_RS10415
uniprot id: A0A1B2AEN3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

692370:A6F68 RS08460
gene id: 692370:A6F68_RS08460
uniprot id: A0A1B2ADR1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

692370:A6F68 RS11990
gene id: 692370:A6F68_RS11990
uniprot id: A0A1B2AFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

692370:A6F68 RS03200
gene id: 692370:A6F68_RS03200
uniprot id: A0A1B2AAG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

692370:A6F68 RS05105
gene id: 692370:A6F68_RS05105
uniprot id: A0A1B2ABL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

692370:A6F68 RS10115
gene id: 692370:A6F68_RS10115
uniprot id: A0A1B2AEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

692370:A6F68 RS04835
gene id: 692370:A6F68_RS04835
uniprot id: A0A1B2ABM2
names: Similarity
messages: Belongs to the YkuD family.

692370:A6F68 RS14460
gene id: 692370:A6F68_RS14460
uniprot id: A0A1B2AGZ4
names: Similarity
messages: Belongs to the Gfa family.

692370:A6F68 RS06910
gene id: 692370:A6F68_RS06910
uniprot id: A0A1B2ACN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS03470
gene id: 692370:A6F68_RS03470
uniprot id: A0A1B2AAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

692370:A6F68 RS00400
gene id: 692370:A6F68_RS00400
uniprot id: A0A1B2A8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

692370:A6F68 RS14500
gene id: 692370:A6F68_RS14500
uniprot id: A0A1B2AH24
names: Similarity
messages: Belongs to the FeoA family.

692370:A6F68 RS03825
gene id: 692370:A6F68_RS03825
uniprot id: A0A1B2AB43
names: Similarity
messages: Belongs to the ArsC family.

692370:A6F68 RS04780
gene id: 692370:A6F68_RS04780
uniprot id: A0A1B2ABF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

692370:A6F68 RS11005
gene id: 692370:A6F68_RS11005
uniprot id: A0A1B2AF42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS00840
gene id: 692370:A6F68_RS00840
uniprot id: A0A1B2A988
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

692370:A6F68 RS14110
gene id: 692370:A6F68_RS14110
uniprot id: A0A1B2AGW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

692370:A6F68 RS10665
gene id: 692370:A6F68_RS10665
uniprot id: A0A1B2AEU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

692370:A6F68 RS15395
gene id: 692370:A6F68_RS15395
uniprot id: A0A1B2A9I6
names: Subcellular Location Annotation
messages: Cytoplasm

692370:A6F68 RS09235
gene id: 692370:A6F68_RS09235
uniprot id: A0A1B2AE57
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

692370:A6F68 RS12695
gene id: 692370:A6F68_RS12695
uniprot id: A0A1B2AG42
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

692370:A6F68 RS01475
gene id: 692370:A6F68_RS01475
uniprot id: A0A1B2A9J7
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

692370:A6F68 RS12635
gene id: 692370:A6F68_RS12635
uniprot id: A0A1B2AFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

692370:A6F68 RS14535
gene id: 692370:A6F68_RS14535
uniprot id: A0A1B2AH45
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

692370:A6F68 RS13085
gene id: 692370:A6F68_RS13085
uniprot id: A0A1B2AG71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07075
gene id: 692370:A6F68_RS07075
uniprot id: A0A1B2ACS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

692370:A6F68 RS02430
gene id: 692370:A6F68_RS02430
uniprot id: A0A1B2AA61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

692370:A6F68 RS13235
gene id: 692370:A6F68_RS13235
uniprot id: A0A1B2AG98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

692370:A6F68 RS02215
gene id: 692370:A6F68_RS02215
uniprot id: A0A1B2A9Z5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

692370:A6F68 RS04935
gene id: 692370:A6F68_RS04935
uniprot id: A0A1B2ABN6
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

692370:A6F68 RS04960
gene id: 692370:A6F68_RS04960
uniprot id: A0A1B2ABK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

692370:A6F68 RS08275
gene id: 692370:A6F68_RS08275
uniprot id: A0A1B2ADL6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

692370:A6F68 RS04270
gene id: 692370:A6F68_RS04270
uniprot id: A0A1B2ABH2
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS01985
gene id: 692370:A6F68_RS01985
uniprot id: A0A1B2A9X0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

692370:A6F68 RS10095
gene id: 692370:A6F68_RS10095
uniprot id: A0A1B2AEL6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS00725
gene id: 692370:A6F68_RS00725
uniprot id: A0A1B2A945
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

692370:A6F68 RS01115
gene id: 692370:A6F68_RS01115
uniprot id: A0A1B2A9B4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS02010
gene id: 692370:A6F68_RS02010
uniprot id: A0A1B2A9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS05690
gene id: 692370:A6F68_RS05690
uniprot id: A0A1B2ABY2
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

692370:A6F68 RS11605
gene id: 692370:A6F68_RS11605
uniprot id: A0A1B2AFC4
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS06110
gene id: 692370:A6F68_RS06110
uniprot id: A0A1B2AC89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

692370:A6F68 RS09505
gene id: 692370:A6F68_RS09505
uniprot id: A0A1B2AEF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

692370:A6F68 RS11695
gene id: 692370:A6F68_RS11695
uniprot id: A0A1B2AFI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

692370:A6F68 RS07140
gene id: 692370:A6F68_RS07140
uniprot id: A0A1B2AD36
names: Similarity
messages: Belongs to the Gfa family.

692370:A6F68 RS07450
gene id: 692370:A6F68_RS07450
uniprot id: A0A1B2AD58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

692370:A6F68 RS09825
gene id: 692370:A6F68_RS09825
uniprot id: A0A1B2AEI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

692370:A6F68 RS14315
gene id: 692370:A6F68_RS14315
uniprot id: A0A1B2AGW6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS12360
gene id: 692370:A6F68_RS12360
uniprot id: A0A1B2AFV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

692370:A6F68 RS07215
gene id: 692370:A6F68_RS07215
uniprot id: A0A1B2ACU7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

692370:A6F68 RS00260
gene id: 692370:A6F68_RS00260
uniprot id: A0A1B2A936
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

692370:A6F68 RS07690
gene id: 692370:A6F68_RS07690
uniprot id: A0A1B2AD51
names: Similarity
messages: Belongs to the asparaginase 1 family.

692370:A6F68 RS12115
gene id: 692370:A6F68_RS12115
uniprot id: A0A1B2AFM6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

692370:A6F68 RS03175
gene id: 692370:A6F68_RS03175
uniprot id: A0A1B2AAR1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

692370:A6F68 RS08265
gene id: 692370:A6F68_RS08265
uniprot id: A0A1B2ADG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

692370:A6F68 RS05380
gene id: 692370:A6F68_RS05380
uniprot id: A0A1B2ABS0
names: Similarity
messages: Belongs to the ros/MucR family.

692370:A6F68 RS12365
gene id: 692370:A6F68_RS12365
uniprot id: A0A1B2AFS1
names: Similarity
messages: Belongs to the TPP enzyme family.

692370:A6F68 RS01950
gene id: 692370:A6F68_RS01950
uniprot id: A0A1B2AA07
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS14285
gene id: 692370:A6F68_RS14285
uniprot id: A0A1B2AGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

692370:A6F68 RS02070
gene id: 692370:A6F68_RS02070
uniprot id: A0A1B2A9W4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

692370:A6F68 RS11600
gene id: 692370:A6F68_RS11600
uniprot id: A0A1B2AFC0
names: Similarity
messages: Belongs to the alanine racemase family.

692370:A6F68 RS06940
gene id: 692370:A6F68_RS06940
uniprot id: A0A1B2ACQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

692370:A6F68 RS01890
gene id: 692370:A6F68_RS01890
uniprot id: A0A1B2A9V0
names: Similarity
messages: Belongs to the cytochrome P450 family.

692370:A6F68 RS06930
gene id: 692370:A6F68_RS06930
uniprot id: A0A1B2ACS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS03085
gene id: 692370:A6F68_RS03085
uniprot id: A0A1B2AAG0
names: Subunit
messages: Homotetramer.

692370:A6F68 RS11285
gene id: 692370:A6F68_RS11285
uniprot id: A0A1B2AF52
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

692370:A6F68 RS07000
gene id: 692370:A6F68_RS07000
uniprot id: A0A1B2ACW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

692370:A6F68 RS08150
gene id: 692370:A6F68_RS08150
uniprot id: A0A1B2ADE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

692370:A6F68 RS04700
gene id: 692370:A6F68_RS04700
uniprot id: A0A1B2ABC6
names: Similarity
messages: Belongs to the oxoprolinase family.

692370:A6F68 RS09275
gene id: 692370:A6F68_RS09275
uniprot id: A0A1B2AE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

692370:A6F68 RS09115
gene id: 692370:A6F68_RS09115
uniprot id: A0A1B2ADZ4
names: Similarity
messages: Belongs to the ros/MucR family.

692370:A6F68 RS00870
gene id: 692370:A6F68_RS00870
uniprot id: A0A1B2A963
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

692370:A6F68 RS06145
gene id: 692370:A6F68_RS06145
uniprot id: A0A1B2ACD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS07470
gene id: 692370:A6F68_RS07470
uniprot id: A0A1B2AD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS09995
gene id: 692370:A6F68_RS09995
uniprot id: A0A1B2AEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

692370:A6F68 RS04735
gene id: 692370:A6F68_RS04735
uniprot id: A0A1B2ABE9
names: Similarity
messages: Belongs to the ArsC family.

692370:A6F68 RS12295
gene id: 692370:A6F68_RS12295
uniprot id: A0A1B2AFW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS14125
gene id: 692370:A6F68_RS14125
uniprot id: A0A1B2AGT6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

692370:A6F68 RS11975
gene id: 692370:A6F68_RS11975
uniprot id: A0A1B2AFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

692370:A6F68 RS07995
gene id: 692370:A6F68_RS07995
uniprot id: A0A1B2ADL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

692370:A6F68 RS12510
gene id: 692370:A6F68_RS12510
uniprot id: A0A1B2AFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

692370:A6F68 RS06860
gene id: 692370:A6F68_RS06860
uniprot id: A0A1B2ACM1
names: Similarity
messages: Belongs to the TrpF family.

692370:A6F68 RS09625
gene id: 692370:A6F68_RS09625
uniprot id: A0A1B2AED8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

692370:A6F68 RS09010
gene id: 692370:A6F68_RS09010
uniprot id: A0A1B2ADW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

692370:A6F68 RS09725
gene id: 692370:A6F68_RS09725
uniprot id: A0A1B2AEG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

692370:A6F68 RS12415
gene id: 692370:A6F68_RS12415
uniprot id: A0A1B2AFT1
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

692370:A6F68 RS02465
gene id: 692370:A6F68_RS02465
uniprot id: A0A1B2AAC3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

692370:A6F68 RS10870
gene id: 692370:A6F68_RS10870
uniprot id: A0A1B2AEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

692370:A6F68 RS04555
gene id: 692370:A6F68_RS04555
uniprot id: A0A1B2AB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS02975
gene id: 692370:A6F68_RS02975
uniprot id: A0A1B2AAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

692370:A6F68 RS08060
gene id: 692370:A6F68_RS08060
uniprot id: A0A1B2ADH9
names: Similarity
messages: Belongs to the threonine synthase family.

692370:A6F68 RS06990
gene id: 692370:A6F68_RS06990
uniprot id: A0A1B2ACR3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

692370:A6F68 RS12005
gene id: 692370:A6F68_RS12005
uniprot id: A0A1B2AFK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

692370:A6F68 RS12585
gene id: 692370:A6F68_RS12585
uniprot id: A0A1B2AFY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

692370:A6F68 RS10595
gene id: 692370:A6F68_RS10595
uniprot id: A0A1B2AES2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

692370:A6F68 RS03445
gene id: 692370:A6F68_RS03445
uniprot id: A0A1B2AAU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

692370:A6F68 RS13855
gene id: 692370:A6F68_RS13855
uniprot id: A0A1B2AGM2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

692370:A6F68 RS03125
gene id: 692370:A6F68_RS03125
uniprot id: A0A1B2AAQ3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

692370:A6F68 RS07845
gene id: 692370:A6F68_RS07845
uniprot id: A0A1B2ADA2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

692370:A6F68 RS06720
gene id: 692370:A6F68_RS06720
uniprot id: A0A1B2ACQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

692370:A6F68 RS08020
gene id: 692370:A6F68_RS08020
uniprot id: A0A1B2ADA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

692370:A6F68 RS11425
gene id: 692370:A6F68_RS11425
uniprot id: A0A1B2AF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

692370:A6F68 RS06670
gene id: 692370:A6F68_RS06670
uniprot id: A0A1B2ACP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

692370:A6F68 RS09550
gene id: 692370:A6F68_RS09550
uniprot id: A0A1B2AE66
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS02995
gene id: 692370:A6F68_RS02995
uniprot id: A0A1B2AAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

692370:A6F68 RS10820
gene id: 692370:A6F68_RS10820
uniprot id: A0A1B2AF83
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

692370:A6F68 RS08245
gene id: 692370:A6F68_RS08245
uniprot id: A0A1B2ADH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

692370:A6F68 RS11310
gene id: 692370:A6F68_RS11310
uniprot id: A0A1B2AF75
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

692370:A6F68 RS02970
gene id: 692370:A6F68_RS02970
uniprot id: A0A1B2AAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

692370:A6F68 RS10025
gene id: 692370:A6F68_RS10025
uniprot id: A0A1B2AEG2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

692370:A6F68 RS00600
gene id: 692370:A6F68_RS00600
uniprot id: A0A1B2A9C4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

692370:A6F68 RS09255
gene id: 692370:A6F68_RS09255
uniprot id: A0A1B2AEB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

692370:A6F68 RS14135
gene id: 692370:A6F68_RS14135
uniprot id: A0A1B2AGT3
names: Similarity
messages: Belongs to the peptidase M16 family.

692370:A6F68 RS03855
gene id: 692370:A6F68_RS03855
uniprot id: A0A1B2AB23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

692370:A6F68 RS09300
gene id: 692370:A6F68_RS09300
uniprot id: A0A1B2AE23
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

692370:A6F68 RS07515
gene id: 692370:A6F68_RS07515
uniprot id: A0A1B2AD01
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

692370:A6F68 RS11040
gene id: 692370:A6F68_RS11040
uniprot id: A0A1B2AF67
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

692370:A6F68 RS07700
gene id: 692370:A6F68_RS07700
uniprot id: A0A1B2ADF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS10905
gene id: 692370:A6F68_RS10905
uniprot id: A0A1B2AF22
names: Similarity
messages: Belongs to the TrpC family.

692370:A6F68 RS00365
gene id: 692370:A6F68_RS00365
uniprot id: A0A1B2A8W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

692370:A6F68 RS06055
gene id: 692370:A6F68_RS06055
uniprot id: A0A1B2AC70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

692370:A6F68 RS08165
gene id: 692370:A6F68_RS08165
uniprot id: A0A1B2ADE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

692370:A6F68 RS12465
gene id: 692370:A6F68_RS12465
uniprot id: A0A1B2AFX9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

692370:A6F68 RS06200
gene id: 692370:A6F68_RS06200
uniprot id: A0A1B2ACJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

692370:A6F68 RS04365
gene id: 692370:A6F68_RS04365
uniprot id: A0A1B2ABB6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

692370:A6F68 RS00760
gene id: 692370:A6F68_RS00760
uniprot id: A0A1B2A957
names: Similarity
messages: Belongs to the cytochrome P450 family.

692370:A6F68 RS12165
gene id: 692370:A6F68_RS12165
uniprot id: A0A1B2AFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell inner membrane

692370:A6F68 RS03900
gene id: 692370:A6F68_RS03900
uniprot id: A0A1B2AAW3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

692370:A6F68 RS11000
gene id: 692370:A6F68_RS11000
uniprot id: A0A1B2AF06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS06275
gene id: 692370:A6F68_RS06275
uniprot id: A0A1B2ACA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

692370:A6F68 RS11870
gene id: 692370:A6F68_RS11870
uniprot id: A0A1B2AFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

692370:A6F68 RS00890
gene id: 692370:A6F68_RS00890
uniprot id: A0A1B2A998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

692370:A6F68 RS07525
gene id: 692370:A6F68_RS07525
uniprot id: A0A1B2AD08
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

692370:A6F68 RS08450
gene id: 692370:A6F68_RS08450
uniprot id: A0A1B2ADJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

692370:A6F68 RS12600
gene id: 692370:A6F68_RS12600
uniprot id: A0A1B2AFX4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

692370:A6F68 RS03635
gene id: 692370:A6F68_RS03635
uniprot id: A0A1B2AAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

692370:A6F68 RS07400
gene id: 692370:A6F68_RS07400
uniprot id: A0A1B2AD48
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS14225
gene id: 692370:A6F68_RS14225
uniprot id: A0A1B2AGX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

692370:A6F68 RS08190
gene id: 692370:A6F68_RS08190
uniprot id: A0A1B2ADG5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

692370:A6F68 RS12620
gene id: 692370:A6F68_RS12620
uniprot id: A0A1B2AFY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

692370:A6F68 RS07415
gene id: 692370:A6F68_RS07415
uniprot id: A0A1B2AD47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

692370:A6F68 RS00930
gene id: 692370:A6F68_RS00930
uniprot id: A0A1B2A985
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

692370:A6F68 RS12765
gene id: 692370:A6F68_RS12765
uniprot id: A0A1B2AG11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

692370:A6F68 RS11080
gene id: 692370:A6F68_RS11080
uniprot id: A0A1B2AF12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

692370:A6F68 RS11490
gene id: 692370:A6F68_RS11490
uniprot id: A0A1B2AFA6
names: Similarity
messages: Belongs to the MreC family.

692370:A6F68 RS09100
gene id: 692370:A6F68_RS09100
uniprot id: A0A1B2ADY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS03135
gene id: 692370:A6F68_RS03135
uniprot id: A0A1B2AAH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

692370:A6F68 RS06835
gene id: 692370:A6F68_RS06835
uniprot id: A0A1B2ACR0
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS06365
gene id: 692370:A6F68_RS06365
uniprot id: A0A1B2ACI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

692370:A6F68 RS08040
gene id: 692370:A6F68_RS08040
uniprot id: A0A1B2ADD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

692370:A6F68 RS04025
gene id: 692370:A6F68_RS04025
uniprot id: A0A1B2ABB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

692370:A6F68 RS09065
gene id: 692370:A6F68_RS09065
uniprot id: A0A1B2ADY2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

692370:A6F68 RS07980
gene id: 692370:A6F68_RS07980
uniprot id: A0A1B2AD96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

692370:A6F68 RS04875
gene id: 692370:A6F68_RS04875
uniprot id: A0A1B2ABH7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

692370:A6F68 RS12700
gene id: 692370:A6F68_RS12700
uniprot id: A0A1B2AFZ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

692370:A6F68 RS08655
gene id: 692370:A6F68_RS08655
uniprot id: A0A1B2ADQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

692370:A6F68 RS13905
gene id: 692370:A6F68_RS13905
uniprot id: A0A1B2AGN2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

692370:A6F68 RS01130
gene id: 692370:A6F68_RS01130
uniprot id: A0A1B2A9C6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

692370:A6F68 RS04510
gene id: 692370:A6F68_RS04510
uniprot id: A0A1B2ABE8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

692370:A6F68 RS09885
gene id: 692370:A6F68_RS09885
uniprot id: A0A1B2AEB8
names: Similarity
messages: Belongs to the fabD family.

692370:A6F68 RS08010
gene id: 692370:A6F68_RS08010
uniprot id: A0A1B2ADG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

692370:A6F68 RS07030
gene id: 692370:A6F68_RS07030
uniprot id: A0A1B2ACU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

692370:A6F68 RS08885
gene id: 692370:A6F68_RS08885
uniprot id: A0A1B2ADS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

692370:A6F68 RS01285
gene id: 692370:A6F68_RS01285
uniprot id: A0A1B2A9K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

692370:A6F68 RS05680
gene id: 692370:A6F68_RS05680
uniprot id: A0A1B2AC49
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS05590
gene id: 692370:A6F68_RS05590
uniprot id: A0A1B2AC17
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

692370:A6F68 RS00030
gene id: 692370:A6F68_RS00030
uniprot id: A0A1B2A8T5
names: Subcellular Location Annotation
messages: Membrane

692370:A6F68 RS06880
gene id: 692370:A6F68_RS06880
uniprot id: A0A1B2ACR5
names: Similarity
messages: Belongs to the UPF0758 family.