68278:IGS69 RS21045
gene id: 68278:IGS69_RS21045
uniprot id: A0A7G1NL81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

68278:IGS69 RS21040
gene id: 68278:IGS69_RS21040
uniprot id: A0A7G1NHT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

68278:IGS69 RS20940
gene id: 68278:IGS69_RS20940
uniprot id: A0A7G1NL63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

68278:IGS69 RS21050
gene id: 68278:IGS69_RS21050
uniprot id: A0A7G1NI34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

68278:IGS69 RS26125
gene id: 68278:IGS69_RS26125
uniprot id: A0A7G1NP58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

68278:IGS69 RS05180
gene id: 68278:IGS69_RS05180
uniprot id: A0A7G1NBX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

68278:IGS69 RS20965
gene id: 68278:IGS69_RS20965
uniprot id: A0A7G1NMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

68278:IGS69 RS17325
gene id: 68278:IGS69_RS17325
uniprot id: A0A7G1NIR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

68278:IGS69 RS20515
gene id: 68278:IGS69_RS20515
uniprot id: A0A7G1NME4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

68278:IGS69 RS08985
gene id: 68278:IGS69_RS08985
uniprot id: A0A7G1NE63
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

68278:IGS69 RS21140
gene id: 68278:IGS69_RS21140
uniprot id: A0A7G1NHV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

68278:IGS69 RS20960
gene id: 68278:IGS69_RS20960
uniprot id: A0A7G1NL64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

68278:IGS69 RS20970
gene id: 68278:IGS69_RS20970
uniprot id: A0A7G1NLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

68278:IGS69 RS21090
gene id: 68278:IGS69_RS21090
uniprot id: A0A7G1NL89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

68278:IGS69 RS20215
gene id: 68278:IGS69_RS20215
uniprot id: A0A7G1NHM2
names: Similarity
messages: Belongs to the WXG100 family.

68278:IGS69 RS25095
gene id: 68278:IGS69_RS25095
uniprot id: A0A7G1NLL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

68278:IGS69 RS18190
gene id: 68278:IGS69_RS18190
uniprot id: A0A7G1NF98
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS29185
gene id: 68278:IGS69_RS29185
uniprot id: A0A7G1NR95
names: Subcellular Location Annotation
messages: Membrane

68278:IGS69 RS21110
gene id: 68278:IGS69_RS21110
uniprot id: A0A7G1NL90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

68278:IGS69 RS21130
gene id: 68278:IGS69_RS21130
uniprot id: A0A7G1NGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

68278:IGS69 RS25085
gene id: 68278:IGS69_RS25085
uniprot id: A0A7G1NNI6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

68278:IGS69 RS08310
gene id: 68278:IGS69_RS08310
uniprot id: A0A7G1NFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

68278:IGS69 RS21105
gene id: 68278:IGS69_RS21105
uniprot id: A0A7G1NGX6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

68278:IGS69 RS32990
gene id: 68278:IGS69_RS32990
uniprot id: A0A7G1NQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

68278:IGS69 RS13130
gene id: 68278:IGS69_RS13130
uniprot id: A0A7G1NCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

68278:IGS69 RS21145
gene id: 68278:IGS69_RS21145
uniprot id: A0A7G1NL98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

68278:IGS69 RS32730
gene id: 68278:IGS69_RS32730
uniprot id: A0A7G1NPN7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

68278:IGS69 RS28920
gene id: 68278:IGS69_RS28920
uniprot id: A0A7G1NNP5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

68278:IGS69 RS13025
gene id: 68278:IGS69_RS13025
uniprot id: A0A7G1NCD7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

68278:IGS69 RS23575
gene id: 68278:IGS69_RS23575
uniprot id: A0A7G1NMH8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

68278:IGS69 RS20855
gene id: 68278:IGS69_RS20855
uniprot id: A0A7G1NGT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

68278:IGS69 RS31120
gene id: 68278:IGS69_RS31120
uniprot id: A0A7G1NMS9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

68278:IGS69 RS08835
gene id: 68278:IGS69_RS08835
uniprot id: A0A7G1NE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

68278:IGS69 RS17425
gene id: 68278:IGS69_RS17425
uniprot id: A0A7G1NKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

68278:IGS69 RS25255
gene id: 68278:IGS69_RS25255
uniprot id: A0A7G1NP15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

68278:IGS69 RS29075
gene id: 68278:IGS69_RS29075
uniprot id: A0A7G1NSE2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

68278:IGS69 RS21360
gene id: 68278:IGS69_RS21360
uniprot id: A0A7G1NJL8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

68278:IGS69 RS09075
gene id: 68278:IGS69_RS09075
uniprot id: A0A7G1NA34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

68278:IGS69 RS24210
gene id: 68278:IGS69_RS24210
uniprot id: A0A7G1NMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

68278:IGS69 RS21025
gene id: 68278:IGS69_RS21025
uniprot id: A0A7G1NLC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

68278:IGS69 RS05390
gene id: 68278:IGS69_RS05390
uniprot id: A0A7G1N894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

68278:IGS69 RS07620
gene id: 68278:IGS69_RS07620
uniprot id: A0A7G1NF19
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

68278:IGS69 RS21175
gene id: 68278:IGS69_RS21175
uniprot id: A0A7G1NLE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

68278:IGS69 RS34040
gene id: 68278:IGS69_RS34040
uniprot id: A0A7G1NQF1
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS13005
gene id: 68278:IGS69_RS13005
uniprot id: A0A7G1ND91
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

68278:IGS69 RS06875
gene id: 68278:IGS69_RS06875
uniprot id: A0A7G1NEM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

68278:IGS69 RS04830
gene id: 68278:IGS69_RS04830
uniprot id: A0A7G1N7T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

68278:IGS69 RS17195
gene id: 68278:IGS69_RS17195
uniprot id: A0A7G1NFQ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

68278:IGS69 RS21155
gene id: 68278:IGS69_RS21155
uniprot id: A0A7G1NJI3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

68278:IGS69 RS05970
gene id: 68278:IGS69_RS05970
uniprot id: A0A7G1N8K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

68278:IGS69 RS30910
gene id: 68278:IGS69_RS30910
uniprot id: A0A7G1NME9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

68278:IGS69 RS21030
gene id: 68278:IGS69_RS21030
uniprot id: A0A7G1NKX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

68278:IGS69 RS21075
gene id: 68278:IGS69_RS21075
uniprot id: A0A7G1NLC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

68278:IGS69 RS25745
gene id: 68278:IGS69_RS25745
uniprot id: A0A7G1NL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

68278:IGS69 RS19215
gene id: 68278:IGS69_RS19215
uniprot id: A0A7G1NGZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

68278:IGS69 RS25065
gene id: 68278:IGS69_RS25065
uniprot id: A0A7G1NNY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

68278:IGS69 RS21320
gene id: 68278:IGS69_RS21320
uniprot id: A0A7G1NMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

68278:IGS69 RS24315
gene id: 68278:IGS69_RS24315
uniprot id: A0A7G1NIU2
names: Similarity
messages: Belongs to the UPF0045 family.

68278:IGS69 RS24130
gene id: 68278:IGS69_RS24130
uniprot id: A0A7G1NK08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

68278:IGS69 RS21100
gene id: 68278:IGS69_RS21100
uniprot id: A0A7G1NJH6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

68278:IGS69 RS22755
gene id: 68278:IGS69_RS22755
uniprot id: A0A7G1NM33
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

68278:IGS69 RS04610
gene id: 68278:IGS69_RS04610
uniprot id: A0A7G1NBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

68278:IGS69 RS03660
gene id: 68278:IGS69_RS03660
uniprot id: A0A7G1NAY7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

68278:IGS69 RS25140
gene id: 68278:IGS69_RS25140
uniprot id: A0A7G1NKL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

68278:IGS69 RS20915
gene id: 68278:IGS69_RS20915
uniprot id: A0A7G1NMM4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

68278:IGS69 RS20860
gene id: 68278:IGS69_RS20860
uniprot id: A0A7G1NL40
names: Similarity
messages: Belongs to the UPF0336 family.

68278:IGS69 RS13445
gene id: 68278:IGS69_RS13445
uniprot id: A0A7G1NCK3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

68278:IGS69 RS21055
gene id: 68278:IGS69_RS21055
uniprot id: A0A7G1NJG9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

68278:IGS69 RS05115
gene id: 68278:IGS69_RS05115
uniprot id: A0A7G1NBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

68278:IGS69 RS05725
gene id: 68278:IGS69_RS05725
uniprot id: A0A7G1NCN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

68278:IGS69 RS22990
gene id: 68278:IGS69_RS22990
uniprot id: A0A7G1NKK1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

68278:IGS69 RS20470
gene id: 68278:IGS69_RS20470
uniprot id: A0A7G1NL29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

68278:IGS69 RS11135
gene id: 68278:IGS69_RS11135
uniprot id: A0A7G1NFC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

68278:IGS69 RS20195
gene id: 68278:IGS69_RS20195
uniprot id: A0A7G1NKF9
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS21150
gene id: 68278:IGS69_RS21150
uniprot id: A0A7G1NI54
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

68278:IGS69 RS20955
gene id: 68278:IGS69_RS20955
uniprot id: A0A7G1NGV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

68278:IGS69 RS21065
gene id: 68278:IGS69_RS21065
uniprot id: A0A7G1NL84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

68278:IGS69 RS08445
gene id: 68278:IGS69_RS08445
uniprot id: A0A7G1NCI8
names: Similarity
messages: Belongs to the YggT family.

68278:IGS69 RS16055
gene id: 68278:IGS69_RS16055
uniprot id: A0A7G1NK45
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

68278:IGS69 RS18135
gene id: 68278:IGS69_RS18135
uniprot id: A0A7G1NJN4
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS22640
gene id: 68278:IGS69_RS22640
uniprot id: A0A7G1NJ71
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

68278:IGS69 RS31695
gene id: 68278:IGS69_RS31695
uniprot id: A0A7G1NSM9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

68278:IGS69 RS33635
gene id: 68278:IGS69_RS33635
uniprot id: A0A7G1NR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

68278:IGS69 RS05010
gene id: 68278:IGS69_RS05010
uniprot id: A0A7G1NDJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

68278:IGS69 RS11130
gene id: 68278:IGS69_RS11130
uniprot id: A0A7G1NC89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

68278:IGS69 RS27195
gene id: 68278:IGS69_RS27195
uniprot id: A0A7G1NK78
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

68278:IGS69 RS10660
gene id: 68278:IGS69_RS10660
uniprot id: A0A7G1NF66
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

68278:IGS69 RS05905
gene id: 68278:IGS69_RS05905
uniprot id: A0A7G1NCA7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

68278:IGS69 RS21245
gene id: 68278:IGS69_RS21245
uniprot id: A0A7G1NLB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

68278:IGS69 RS05720
gene id: 68278:IGS69_RS05720
uniprot id: A0A7G1N8F3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

68278:IGS69 RS19295
gene id: 68278:IGS69_RS19295
uniprot id: A0A7G1NJW0
names: Similarity
messages: Belongs to the UPF0145 family.

68278:IGS69 RS14995
gene id: 68278:IGS69_RS14995
uniprot id: A0A7G1NDI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

68278:IGS69 RS09960
gene id: 68278:IGS69_RS09960
uniprot id: A0A7G1NEQ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

68278:IGS69 RS15215
gene id: 68278:IGS69_RS15215
uniprot id: A0A7G1NHP9
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS19310
gene id: 68278:IGS69_RS19310
uniprot id: A0A7G1NK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

68278:IGS69 RS17840
gene id: 68278:IGS69_RS17840
uniprot id: A0A7G1NJ19
names: Similarity
messages: Belongs to the LOR family.

68278:IGS69 RS28730
gene id: 68278:IGS69_RS28730
uniprot id: A0A7G1NQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

68278:IGS69 RS21085
gene id: 68278:IGS69_RS21085
uniprot id: A0A7G1NHU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

68278:IGS69 RS25270
gene id: 68278:IGS69_RS25270
uniprot id: A0A7G1NKF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

68278:IGS69 RS25590
gene id: 68278:IGS69_RS25590
uniprot id: A0A7G1NNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

68278:IGS69 RS05050
gene id: 68278:IGS69_RS05050
uniprot id: A0A7G1N825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

68278:IGS69 RS22620
gene id: 68278:IGS69_RS22620
uniprot id: A0A7G1NLZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

68278:IGS69 RS26080
gene id: 68278:IGS69_RS26080
uniprot id: A0A7G1NKW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

68278:IGS69 RS05060
gene id: 68278:IGS69_RS05060
uniprot id: A0A7G1NDK9
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

68278:IGS69 RS21010
gene id: 68278:IGS69_RS21010
uniprot id: A0A7G1NGW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

68278:IGS69 RS24200
gene id: 68278:IGS69_RS24200
uniprot id: A0A7G1NPL6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

68278:IGS69 RS21035
gene id: 68278:IGS69_RS21035
uniprot id: A0A7G1NGX2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

68278:IGS69 RS22260
gene id: 68278:IGS69_RS22260
uniprot id: A0A7G1NIT0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

68278:IGS69 RS08635
gene id: 68278:IGS69_RS08635
uniprot id: A0A7G1NDZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

68278:IGS69 RS17185
gene id: 68278:IGS69_RS17185
uniprot id: A0A7G1NFM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

68278:IGS69 RS19540
gene id: 68278:IGS69_RS19540
uniprot id: A0A7G1NK21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

68278:IGS69 RS30550
gene id: 68278:IGS69_RS30550
uniprot id: A0A7G1NMG3
names: Subcellular Location Annotation
messages: Membrane

68278:IGS69 RS11055
gene id: 68278:IGS69_RS11055
uniprot id: A0A7G1NFH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

68278:IGS69 RS13115
gene id: 68278:IGS69_RS13115
uniprot id: A0A7G1NGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

68278:IGS69 RS21180
gene id: 68278:IGS69_RS21180
uniprot id: A0A7G1NL58
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

68278:IGS69 RS15350
gene id: 68278:IGS69_RS15350
uniprot id: A0A7G1NI05
names: Subcellular Location Annotation
messages: Cytoplasm

68278:IGS69 RS12210
gene id: 68278:IGS69_RS12210
uniprot id: A0A7G1NG04
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

68278:IGS69 RS20935
gene id: 68278:IGS69_RS20935
uniprot id: A0A7G1NHR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

68278:IGS69 RS05915
gene id: 68278:IGS69_RS05915
uniprot id: A0A7G1NAZ3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

68278:IGS69 RS20730
gene id: 68278:IGS69_RS20730
uniprot id: A0A7G1NHX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

68278:IGS69 RS24795
gene id: 68278:IGS69_RS24795
uniprot id: A0A7G1NNS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

68278:IGS69 RS20465
gene id: 68278:IGS69_RS20465
uniprot id: A0A7G1NMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

68278:IGS69 RS05955
gene id: 68278:IGS69_RS05955
uniprot id: A0A7G1NCB7
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

68278:IGS69 RS20920
gene id: 68278:IGS69_RS20920
uniprot id: A0A7G1NLA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

68278:IGS69 RS12730
gene id: 68278:IGS69_RS12730
uniprot id: A0A7G1NG98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

68278:IGS69 RS18105
gene id: 68278:IGS69_RS18105
uniprot id: A0A7G1NJH2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

68278:IGS69 RS28735
gene id: 68278:IGS69_RS28735
uniprot id: A0A7G1NS60
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

68278:IGS69 RS18675
gene id: 68278:IGS69_RS18675
uniprot id: A0A7G1NI33
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

68278:IGS69 RS19555
gene id: 68278:IGS69_RS19555
uniprot id: A0A7G1NKD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

68278:IGS69 RS20905
gene id: 68278:IGS69_RS20905
uniprot id: A0A7G1NGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

68278:IGS69 RS31115
gene id: 68278:IGS69_RS31115
uniprot id: A0A7G1NS62
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

68278:IGS69 RS24270
gene id: 68278:IGS69_RS24270
uniprot id: A0A7G1NJS9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.