67345:CP972 RS10470
gene id: 67345:CP972_RS10470
uniprot id: A0A5J6H8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS21705
gene id: 67345:CP972_RS21705
uniprot id: A0A5J6H716
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS11645
gene id: 67345:CP972_RS11645
uniprot id: A0A5J6GWD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

67345:CP972 RS11640
gene id: 67345:CP972_RS11640
uniprot id: A0A5J6H7R5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

67345:CP972 RS09670
gene id: 67345:CP972_RS09670
uniprot id: A0A5J6GVC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

67345:CP972 RS28940
gene id: 67345:CP972_RS28940
uniprot id: A0A5J6H7Y5
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS33780
gene id: 67345:CP972_RS33780
uniprot id: A0A5J6HEE8
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS29865
gene id: 67345:CP972_RS29865
uniprot id: A0A5J6H8C8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

67345:CP972 RS17265
gene id: 67345:CP972_RS17265
uniprot id: A0A5J6H4T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS16785
gene id: 67345:CP972_RS16785
uniprot id: A0A5J6H1X4
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

67345:CP972 RS26250
gene id: 67345:CP972_RS26250
uniprot id: A0A5J6H7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

67345:CP972 RS25770
gene id: 67345:CP972_RS25770
uniprot id: A0A5J6H6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS06465
gene id: 67345:CP972_RS06465
uniprot id: A0A5J6GYB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

67345:CP972 RS13310
gene id: 67345:CP972_RS13310
uniprot id: A0A5J6HF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS11360
gene id: 67345:CP972_RS11360
uniprot id: A0A5J6GV84
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS07150
gene id: 67345:CP972_RS07150
uniprot id: A0A5J6GXI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS21395
gene id: 67345:CP972_RS21395
uniprot id: A0A5J6H0J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

67345:CP972 RS20090
gene id: 67345:CP972_RS20090
uniprot id: A0A5J6H4Q6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

67345:CP972 RS16895
gene id: 67345:CP972_RS16895
uniprot id: A0A5J6H244
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

67345:CP972 RS15790
gene id: 67345:CP972_RS15790
uniprot id: A0A5J6GX89
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09565
gene id: 67345:CP972_RS09565
uniprot id: A0A5J6GVA1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

67345:CP972 RS16245
gene id: 67345:CP972_RS16245
uniprot id: A0A5J6H490
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS28370
gene id: 67345:CP972_RS28370
uniprot id: A0A5J6HB25
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

67345:CP972 RS29830
gene id: 67345:CP972_RS29830
uniprot id: A0A5J6H7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS21280
gene id: 67345:CP972_RS21280
uniprot id: A0A5J6H8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

67345:CP972 RS30845
gene id: 67345:CP972_RS30845
uniprot id: A0A5J6H8T8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS29735
gene id: 67345:CP972_RS29735
uniprot id: A0A5J6H440
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

67345:CP972 RS00220
gene id: 67345:CP972_RS00220
uniprot id: A0A5J6GUF1
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS06410
gene id: 67345:CP972_RS06410
uniprot id: A0A5J6H1H1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS28375
gene id: 67345:CP972_RS28375
uniprot id: A0A5J6H417
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS19990
gene id: 67345:CP972_RS19990
uniprot id: A0A5J6H627
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

67345:CP972 RS04985
gene id: 67345:CP972_RS04985
uniprot id: A0A5J6GWE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

67345:CP972 RS21985
gene id: 67345:CP972_RS21985
uniprot id: A0A5J6H142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS29965
gene id: 67345:CP972_RS29965
uniprot id: A0A5J6H8F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

67345:CP972 RS15045
gene id: 67345:CP972_RS15045
uniprot id: A0A5J6H194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

67345:CP972 RS26740
gene id: 67345:CP972_RS26740
uniprot id: A0A5J6HB94
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS09740
gene id: 67345:CP972_RS09740
uniprot id: A0A5J6GYI5
names: Similarity
messages: Belongs to the arsA ATPase family.

67345:CP972 RS08770
gene id: 67345:CP972_RS08770
uniprot id: A0A5J6GU41
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS14085
gene id: 67345:CP972_RS14085
uniprot id: A0A5J6H250
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

67345:CP972 RS33135
gene id: 67345:CP972_RS33135
uniprot id: A0A5J6H5M3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

67345:CP972 RS28265
gene id: 67345:CP972_RS28265
uniprot id: A0A5J6HB07
names: Similarity
messages: Belongs to the terpene synthase family.

67345:CP972 RS19995
gene id: 67345:CP972_RS19995
uniprot id: A0A5J6H032
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

67345:CP972 RS11810
gene id: 67345:CP972_RS11810
uniprot id: A0A5J6GWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS06330
gene id: 67345:CP972_RS06330
uniprot id: A0A5J6GSR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

67345:CP972 RS28215
gene id: 67345:CP972_RS28215
uniprot id: A0A5J6HAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS31035
gene id: 67345:CP972_RS31035
uniprot id: A0A5J6H8U1
names: Similarity
messages: Belongs to the Dps family.

67345:CP972 RS21240
gene id: 67345:CP972_RS21240
uniprot id: A0A5J6H0Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

67345:CP972 RS27450
gene id: 67345:CP972_RS27450
uniprot id: A0A5J6H362
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17425
gene id: 67345:CP972_RS17425
uniprot id: A0A5J6H278
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

67345:CP972 RS03070
gene id: 67345:CP972_RS03070
uniprot id: A0A5J6GVH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

67345:CP972 RS33275
gene id: 67345:CP972_RS33275
uniprot id: A0A5J6HAY0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

67345:CP972 RS26005
gene id: 67345:CP972_RS26005
uniprot id: A0A5J6H9P9
names: Similarity
messages: Belongs to the Dps family.

67345:CP972 RS20485
gene id: 67345:CP972_RS20485
uniprot id: A0A5J6H3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

67345:CP972 RS25045
gene id: 67345:CP972_RS25045
uniprot id: A0A5J6H758
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS18380
gene id: 67345:CP972_RS18380
uniprot id: A0A5J6H150
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

67345:CP972 RS14925
gene id: 67345:CP972_RS14925
uniprot id: A0A5J6H161
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

67345:CP972 RS07890
gene id: 67345:CP972_RS07890
uniprot id: A0A5J6GYZ1
names: Similarity
messages: Belongs to the TlyA family.

67345:CP972 RS24295
gene id: 67345:CP972_RS24295
uniprot id: A0A5J6H156
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS14445
gene id: 67345:CP972_RS14445
uniprot id: A0A5J6GWN4
names: Similarity
messages: Belongs to the PGI/PMI family.

67345:CP972 RS31235
gene id: 67345:CP972_RS31235
uniprot id: A0A5J6H5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

67345:CP972 RS21315
gene id: 67345:CP972_RS21315
uniprot id: A0A5J6H447
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

67345:CP972 RS05840
gene id: 67345:CP972_RS05840
uniprot id: A0A5J6GV98
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

67345:CP972 RS06905
gene id: 67345:CP972_RS06905
uniprot id: A0A5J6GXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

67345:CP972 RS25240
gene id: 67345:CP972_RS25240
uniprot id: A0A5J6H643
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

67345:CP972 RS30680
gene id: 67345:CP972_RS30680
uniprot id: A0A5J6H6I1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

67345:CP972 RS29985
gene id: 67345:CP972_RS29985
uniprot id: A0A5J6H9L5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

67345:CP972 RS13195
gene id: 67345:CP972_RS13195
uniprot id: A0A5J6HB74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS32180
gene id: 67345:CP972_RS32180
uniprot id: A0A5J6H9E3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

67345:CP972 RS30790
gene id: 67345:CP972_RS30790
uniprot id: A0A5J6H6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

67345:CP972 RS10675
gene id: 67345:CP972_RS10675
uniprot id: A0A5J6H117
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS02855
gene id: 67345:CP972_RS02855
uniprot id: A0A5J6GZQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

67345:CP972 RS32240
gene id: 67345:CP972_RS32240
uniprot id: A0A5J6H579
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS27840
gene id: 67345:CP972_RS27840
uniprot id: A0A5J6H7A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

67345:CP972 RS12355
gene id: 67345:CP972_RS12355
uniprot id: A0A5J6H057
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

67345:CP972 RS26210
gene id: 67345:CP972_RS26210
uniprot id: A0A5J6H9B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

67345:CP972 RS20585
gene id: 67345:CP972_RS20585
uniprot id: A0A5J6H3T8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25200
gene id: 67345:CP972_RS25200
uniprot id: A0A5J6H8U5
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

67345:CP972 RS02145
gene id: 67345:CP972_RS02145
uniprot id: A0A5J6GT73
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS19105
gene id: 67345:CP972_RS19105
uniprot id: A0A5J6H3C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

67345:CP972 RS25990
gene id: 67345:CP972_RS25990
uniprot id: A0A5J6H2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67345:CP972 RS32780
gene id: 67345:CP972_RS32780
uniprot id: A0A5J6H7I9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

67345:CP972 RS22530
gene id: 67345:CP972_RS22530
uniprot id: A0A5J6H990
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

67345:CP972 RS28105
gene id: 67345:CP972_RS28105
uniprot id: A0A5J6H3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

67345:CP972 RS26085
gene id: 67345:CP972_RS26085
uniprot id: A0A5J6H6H3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

67345:CP972 RS21510
gene id: 67345:CP972_RS21510
uniprot id: A0A5J6H6Y5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

67345:CP972 RS22745
gene id: 67345:CP972_RS22745
uniprot id: A0A5J6H5Y2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS20785
gene id: 67345:CP972_RS20785
uniprot id: A0A5J6H429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

67345:CP972 RS06545
gene id: 67345:CP972_RS06545
uniprot id: A0A5J6GT29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

67345:CP972 RS24995
gene id: 67345:CP972_RS24995
uniprot id: A0A5J6H750
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

67345:CP972 RS24340
gene id: 67345:CP972_RS24340
uniprot id: A0A5J6H8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

67345:CP972 RS03295
gene id: 67345:CP972_RS03295
uniprot id: A0A5J6GSI1
names: Similarity
messages: Belongs to the peptidase S45 family.

67345:CP972 RS19395
gene id: 67345:CP972_RS19395
uniprot id: A0A5J6H1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

67345:CP972 RS21410
gene id: 67345:CP972_RS21410
uniprot id: A0A5J6GZU2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS16970
gene id: 67345:CP972_RS16970
uniprot id: A0A5J6H206
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

67345:CP972 RS02505
gene id: 67345:CP972_RS02505
uniprot id: A0A5J6GVJ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

67345:CP972 RS32750
gene id: 67345:CP972_RS32750
uniprot id: A0A5J6HD34
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

67345:CP972 RS19230
gene id: 67345:CP972_RS19230
uniprot id: A0A5J6H4B7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS15815
gene id: 67345:CP972_RS15815
uniprot id: A0A5J6GZY1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS03370
gene id: 67345:CP972_RS03370
uniprot id: A0A5J6GVQ9
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

67345:CP972 RS00535
gene id: 67345:CP972_RS00535
uniprot id: A0A5J6GUG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS30860
gene id: 67345:CP972_RS30860
uniprot id: A0A5J6H9Z0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS02800
gene id: 67345:CP972_RS02800
uniprot id: A0A5J6H628
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS14075
gene id: 67345:CP972_RS14075
uniprot id: A0A5J6GZ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS01925
gene id: 67345:CP972_RS01925
uniprot id: A0A5J6GZA1
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS17635
gene id: 67345:CP972_RS17635
uniprot id: A0A5J6H2F5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS31350
gene id: 67345:CP972_RS31350
uniprot id: A0A5J6HCG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS12030
gene id: 67345:CP972_RS12030
uniprot id: A0A5J6H7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

67345:CP972 RS05540
gene id: 67345:CP972_RS05540
uniprot id: A0A5J6GSB4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

67345:CP972 RS22850
gene id: 67345:CP972_RS22850
uniprot id: A0A5J6H566
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

67345:CP972 RS30465
gene id: 67345:CP972_RS30465
uniprot id: A0A5J6H4G7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

67345:CP972 RS16085
gene id: 67345:CP972_RS16085
uniprot id: A0A5J6HFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67345:CP972 RS21440
gene id: 67345:CP972_RS21440
uniprot id: A0A5J6H8K4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

67345:CP972 RS19145
gene id: 67345:CP972_RS19145
uniprot id: A0A5J6H5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

67345:CP972 RS14825
gene id: 67345:CP972_RS14825
uniprot id: A0A5J6H2E1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS07290
gene id: 67345:CP972_RS07290
uniprot id: A0A5J6GTE3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

67345:CP972 RS08710
gene id: 67345:CP972_RS08710
uniprot id: A0A5J6GUX7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

67345:CP972 RS09280
gene id: 67345:CP972_RS09280
uniprot id: A0A5J6GUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

67345:CP972 RS18150
gene id: 67345:CP972_RS18150
uniprot id: A0A5J6H2Y0
names: Similarity
messages: Belongs to the FemABX family.

67345:CP972 RS08455
gene id: 67345:CP972_RS08455
uniprot id: A0A5J6GWK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS11585
gene id: 67345:CP972_RS11585
uniprot id: A0A5J6GZP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS14440
gene id: 67345:CP972_RS14440
uniprot id: A0A5J6GXL4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS25465
gene id: 67345:CP972_RS25465
uniprot id: A0A5J6H7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

67345:CP972 RS13605
gene id: 67345:CP972_RS13605
uniprot id: A0A5J6GXA0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS08510
gene id: 67345:CP972_RS08510
uniprot id: A0A5J6GWL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS28880
gene id: 67345:CP972_RS28880
uniprot id: A0A5J6H3H8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS07310
gene id: 67345:CP972_RS07310
uniprot id: A0A5J6GW26
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

67345:CP972 RS14580
gene id: 67345:CP972_RS14580
uniprot id: A0A5J6H105
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

67345:CP972 RS27815
gene id: 67345:CP972_RS27815
uniprot id: A0A5J6H3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS23400
gene id: 67345:CP972_RS23400
uniprot id: A0A5J6H9K9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

67345:CP972 RS26155
gene id: 67345:CP972_RS26155
uniprot id: A0A5J6H2M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

67345:CP972 RS27230
gene id: 67345:CP972_RS27230
uniprot id: A0A5J6H4X6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS22070
gene id: 67345:CP972_RS22070
uniprot id: A0A5J6H5N0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

67345:CP972 RS18395
gene id: 67345:CP972_RS18395
uniprot id: A0A5J6H780
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS12725
gene id: 67345:CP972_RS12725
uniprot id: A0A5J6H066
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

67345:CP972 RS27835
gene id: 67345:CP972_RS27835
uniprot id: A0A5J6H565
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS11465
gene id: 67345:CP972_RS11465
uniprot id: A0A5J6GW96
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

67345:CP972 RS16120
gene id: 67345:CP972_RS16120
uniprot id: A0A5J6GXE3
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS23055
gene id: 67345:CP972_RS23055
uniprot id: A0A5J6H617
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS15705
gene id: 67345:CP972_RS15705
uniprot id: A0A5J6H2R0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS23010
gene id: 67345:CP972_RS23010
uniprot id: A0A5J6H172
names: Similarity
messages: Belongs to the YoeB family.

67345:CP972 RS30605
gene id: 67345:CP972_RS30605
uniprot id: A0A5J6H8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS07915
gene id: 67345:CP972_RS07915
uniprot id: A0A5J6GTR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS07305
gene id: 67345:CP972_RS07305
uniprot id: A0A5J6GXF5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

67345:CP972 RS14820
gene id: 67345:CP972_RS14820
uniprot id: A0A5J6H143
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS07825
gene id: 67345:CP972_RS07825
uniprot id: A0A5J6GXU9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

67345:CP972 RS11095
gene id: 67345:CP972_RS11095
uniprot id: A0A5J6H3L1
names: Similarity
messages: Belongs to the thioesterase family.

67345:CP972 RS26375
gene id: 67345:CP972_RS26375
uniprot id: A0A5J6H2Q9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS25475
gene id: 67345:CP972_RS25475
uniprot id: A0A5J6H7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

67345:CP972 RS14930
gene id: 67345:CP972_RS14930
uniprot id: A0A5J6HBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

67345:CP972 RS21840
gene id: 67345:CP972_RS21840
uniprot id: A0A5J6H5I8
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS08170
gene id: 67345:CP972_RS08170
uniprot id: A0A5J6GV40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

67345:CP972 RS25420
gene id: 67345:CP972_RS25420
uniprot id: A0A5J6H8Y4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67345:CP972 RS33145
gene id: 67345:CP972_RS33145
uniprot id: A0A5J6H6Q3
names: Similarity
messages: Belongs to the peptidase S1 family.

67345:CP972 RS22555
gene id: 67345:CP972_RS22555
uniprot id: A0A5J6H518
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

67345:CP972 RS16640
gene id: 67345:CP972_RS16640
uniprot id: A0A5J6HBM3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS31760
gene id: 67345:CP972_RS31760
uniprot id: A0A5J6H507
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

67345:CP972 RS00655
gene id: 67345:CP972_RS00655
uniprot id: A0A5J6GVV0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67345:CP972 RS01480
gene id: 67345:CP972_RS01480
uniprot id: A0A5J6GUT3
names: Similarity
messages: Belongs to the NodU/CmcH family.

67345:CP972 RS24280
gene id: 67345:CP972_RS24280
uniprot id: A0A5J6H1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

67345:CP972 RS11200
gene id: 67345:CP972_RS11200
uniprot id: A0A5J6GZG8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

67345:CP972 RS17620
gene id: 67345:CP972_RS17620
uniprot id: A0A5J6GZ05
names: Similarity
messages: Belongs to the LOR family.

67345:CP972 RS19770
gene id: 67345:CP972_RS19770
uniprot id: A0A5J6H3G5
names: Similarity
messages: Belongs to the GSP E family.

67345:CP972 RS14460
gene id: 67345:CP972_RS14460
uniprot id: A0A5J6GZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

67345:CP972 RS05560
gene id: 67345:CP972_RS05560
uniprot id: A0A5J6H7E6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67345:CP972 RS21340
gene id: 67345:CP972_RS21340
uniprot id: A0A5J6H0I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

67345:CP972 RS24450
gene id: 67345:CP972_RS24450
uniprot id: A0A5J6H2A7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS30755
gene id: 67345:CP972_RS30755
uniprot id: A0A5J6H4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

67345:CP972 RS28515
gene id: 67345:CP972_RS28515
uniprot id: A0A5J6H7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS22385
gene id: 67345:CP972_RS22385
uniprot id: A0A5J6H5S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

67345:CP972 RS04645
gene id: 67345:CP972_RS04645
uniprot id: A0A5J6GXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

67345:CP972 RS06335
gene id: 67345:CP972_RS06335
uniprot id: A0A5J6GXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

67345:CP972 RS12205
gene id: 67345:CP972_RS12205
uniprot id: A0A5J6GYE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

67345:CP972 RS12285
gene id: 67345:CP972_RS12285
uniprot id: A0A5J6H1Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

67345:CP972 RS07735
gene id: 67345:CP972_RS07735
uniprot id: A0A5J6H229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67345:CP972 RS22295
gene id: 67345:CP972_RS22295
uniprot id: A0A5J6H779
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24460
gene id: 67345:CP972_RS24460
uniprot id: A0A5J6H184
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS13940
gene id: 67345:CP972_RS13940
uniprot id: A0A5J6GXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS31940
gene id: 67345:CP972_RS31940
uniprot id: A0A5J6H9A1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67345:CP972 RS08345
gene id: 67345:CP972_RS08345
uniprot id: A0A5J6GZB8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

67345:CP972 RS23005
gene id: 67345:CP972_RS23005
uniprot id: A0A5J6H9F8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS20790
gene id: 67345:CP972_RS20790
uniprot id: A0A5J6H3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS06900
gene id: 67345:CP972_RS06900
uniprot id: A0A5J6HAR8
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

67345:CP972 RS02090
gene id: 67345:CP972_RS02090
uniprot id: A0A5J6GUW9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

67345:CP972 RS06445
gene id: 67345:CP972_RS06445
uniprot id: A0A5J6GXF1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

67345:CP972 RS03270
gene id: 67345:CP972_RS03270
uniprot id: A0A5J6GZX9
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS22000
gene id: 67345:CP972_RS22000
uniprot id: A0A5J6H4G2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS24200
gene id: 67345:CP972_RS24200
uniprot id: A0A5J6H6S0
names: Similarity
messages: Belongs to the DNA photolyase family.

67345:CP972 RS05455
gene id: 67345:CP972_RS05455
uniprot id: A0A5J6GTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS25575
gene id: 67345:CP972_RS25575
uniprot id: A0A5J6H7E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

67345:CP972 RS04185
gene id: 67345:CP972_RS04185
uniprot id: A0A5J6H0B7
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

67345:CP972 RS05190
gene id: 67345:CP972_RS05190
uniprot id: A0A5J6H8B9
names: Similarity
messages: Belongs to the tannase family.

67345:CP972 RS09690
gene id: 67345:CP972_RS09690
uniprot id: A0A5J6GX84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67345:CP972 RS14195
gene id: 67345:CP972_RS14195
uniprot id: A0A5J6GWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

67345:CP972 RS19775
gene id: 67345:CP972_RS19775
uniprot id: A0A5J6H4J9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS12440
gene id: 67345:CP972_RS12440
uniprot id: A0A5J6H149
names: Similarity
messages: Belongs to the FPG family.

67345:CP972 RS19940
gene id: 67345:CP972_RS19940
uniprot id: A0A5J6HBM5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS27415
gene id: 67345:CP972_RS27415
uniprot id: A0A5J6H713
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

67345:CP972 RS09285
gene id: 67345:CP972_RS09285
uniprot id: A0A5J6GYP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

67345:CP972 RS20325
gene id: 67345:CP972_RS20325
uniprot id: A0A5J6H4U8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS25680
gene id: 67345:CP972_RS25680
uniprot id: A0A5J6H6A7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

67345:CP972 RS22675
gene id: 67345:CP972_RS22675
uniprot id: A0A5J6H4S3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS03160
gene id: 67345:CP972_RS03160
uniprot id: A0A5J6GZV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS32355
gene id: 67345:CP972_RS32355
uniprot id: A0A5J6H6B6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS19810
gene id: 67345:CP972_RS19810
uniprot id: A0A5J6H000
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS32445
gene id: 67345:CP972_RS32445
uniprot id: A0A5J6H9J0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

67345:CP972 RS21425
gene id: 67345:CP972_RS21425
uniprot id: A0A5J6H2C3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67345:CP972 RS28525
gene id: 67345:CP972_RS28525
uniprot id: A0A5J6H7S1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS32225
gene id: 67345:CP972_RS32225
uniprot id: A0A5J6H569
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS14115
gene id: 67345:CP972_RS14115
uniprot id: A0A5J6GWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

67345:CP972 RS22605
gene id: 67345:CP972_RS22605
uniprot id: A0A5J6H0C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS28170
gene id: 67345:CP972_RS28170
uniprot id: A0A5J6H7L0
names: Similarity
messages: Belongs to the AHA1 family.

67345:CP972 RS25385
gene id: 67345:CP972_RS25385
uniprot id: A0A5J6H649
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

67345:CP972 RS20970
gene id: 67345:CP972_RS20970
uniprot id: A0A5J6GZM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS11050
gene id: 67345:CP972_RS11050
uniprot id: A0A5J6GV25
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS32685
gene id: 67345:CP972_RS32685
uniprot id: A0A5J6HDW1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS07085
gene id: 67345:CP972_RS07085
uniprot id: A0A5J6GYK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

67345:CP972 RS27150
gene id: 67345:CP972_RS27150
uniprot id: A0A5J6H315
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS28925
gene id: 67345:CP972_RS28925
uniprot id: A0A5J6HBV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

67345:CP972 RS24300
gene id: 67345:CP972_RS24300
uniprot id: A0A5J6H5V7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

67345:CP972 RS25910
gene id: 67345:CP972_RS25910
uniprot id: A0A5J6H968
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

67345:CP972 RS05445
gene id: 67345:CP972_RS05445
uniprot id: A0A5J6GXT3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS24005
gene id: 67345:CP972_RS24005
uniprot id: A0A5J6H6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS13100
gene id: 67345:CP972_RS13100
uniprot id: A0A5J6HBB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

67345:CP972 RS23955
gene id: 67345:CP972_RS23955
uniprot id: A0A5J6H871
names: Similarity
messages: Belongs to the AAA ATPase family.

67345:CP972 RS08360
gene id: 67345:CP972_RS08360
uniprot id: A0A5J6HEY1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

67345:CP972 RS23735
gene id: 67345:CP972_RS23735
uniprot id: A0A5J6H3D2
names: Similarity
messages: Belongs to the Fur family.

67345:CP972 RS21685
gene id: 67345:CP972_RS21685
uniprot id: A0A5J6H4B3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS07790
gene id: 67345:CP972_RS07790
uniprot id: A0A5J6GUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

67345:CP972 RS26180
gene id: 67345:CP972_RS26180
uniprot id: A0A5J6H6H1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

67345:CP972 RS25890
gene id: 67345:CP972_RS25890
uniprot id: A0A5J6H6E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

67345:CP972 RS28600
gene id: 67345:CP972_RS28600
uniprot id: A0A5J6HC32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS00665
gene id: 67345:CP972_RS00665
uniprot id: A0A5J6GRY1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

67345:CP972 RS23185
gene id: 67345:CP972_RS23185
uniprot id: A0A5J6H199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS08185
gene id: 67345:CP972_RS08185
uniprot id: A0A5J6GTV2
names: Similarity
messages: Belongs to the peptidase S8 family.

67345:CP972 RS21350
gene id: 67345:CP972_RS21350
uniprot id: A0A5J6H0S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS25310
gene id: 67345:CP972_RS25310
uniprot id: A0A5J6H2B2
names: Similarity
messages: Belongs to the acylphosphatase family.

67345:CP972 RS05100
gene id: 67345:CP972_RS05100
uniprot id: A0A5J6GUS5
names: Similarity
messages: Belongs to the UPF0047 family.

67345:CP972 RS09345
gene id: 67345:CP972_RS09345
uniprot id: A0A5J6GYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

67345:CP972 RS22095
gene id: 67345:CP972_RS22095
uniprot id: A0A5J6H162
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

67345:CP972 RS08840
gene id: 67345:CP972_RS08840
uniprot id: A0A5J6GWS4
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

67345:CP972 RS01540
gene id: 67345:CP972_RS01540
uniprot id: A0A5J6GV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall. It has a specific arabinofuranose-debranching activity on xylan from gramineae. Acts synergistically with the xylanases and binds specifically to xylan. From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well.
messages: Secreted

67345:CP972 RS25915
gene id: 67345:CP972_RS25915
uniprot id: A0A5J6H2Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

67345:CP972 RS09545
gene id: 67345:CP972_RS09545
uniprot id: A0A5J6H7M3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS05385
gene id: 67345:CP972_RS05385
uniprot id: A0A5J6GUX1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS21210
gene id: 67345:CP972_RS21210
uniprot id: A0A5J6H288
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

67345:CP972 RS11070
gene id: 67345:CP972_RS11070
uniprot id: A0A5J6GXW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

67345:CP972 RS08145
gene id: 67345:CP972_RS08145
uniprot id: A0A5J6GWG0
names: Similarity
messages: Belongs to the peptidase U62 family.

67345:CP972 RS08415
gene id: 67345:CP972_RS08415
uniprot id: A0A5J6H2D3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

67345:CP972 RS23775
gene id: 67345:CP972_RS23775
uniprot id: A0A5J6H0X1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

67345:CP972 RS06995
gene id: 67345:CP972_RS06995
uniprot id: A0A5J6GUG8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS14045
gene id: 67345:CP972_RS14045
uniprot id: A0A5J6HFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS13370
gene id: 67345:CP972_RS13370
uniprot id: A0A5J6GYX9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS23320
gene id: 67345:CP972_RS23320
uniprot id: A0A5J6H1R4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

67345:CP972 RS12130
gene id: 67345:CP972_RS12130
uniprot id: A0A5J6GZX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

67345:CP972 RS19760
gene id: 67345:CP972_RS19760
uniprot id: A0A5J6H3G0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67345:CP972 RS30185
gene id: 67345:CP972_RS30185
uniprot id: A0A5J6H6B0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21355
gene id: 67345:CP972_RS21355
uniprot id: A0A5J6GZT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

67345:CP972 RS20010
gene id: 67345:CP972_RS20010
uniprot id: A0A5J6H3J8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

67345:CP972 RS21720
gene id: 67345:CP972_RS21720
uniprot id: A0A5J6H4N9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

67345:CP972 RS08795
gene id: 67345:CP972_RS08795
uniprot id: A0A5J6GYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

67345:CP972 RS31625
gene id: 67345:CP972_RS31625
uniprot id: A0A5J6HDE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

67345:CP972 RS21000
gene id: 67345:CP972_RS21000
uniprot id: A0A5J6H8C9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS11625
gene id: 67345:CP972_RS11625
uniprot id: A0A5J6H3V5
names: Similarity
messages: Belongs to the FGGY kinase family.

67345:CP972 RS00305
gene id: 67345:CP972_RS00305
uniprot id: A0A5J6GRT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

67345:CP972 RS12985
gene id: 67345:CP972_RS12985
uniprot id: A0A5J6H2H1
names: Similarity
messages: Belongs to the citrate synthase family.

67345:CP972 RS29105
gene id: 67345:CP972_RS29105
uniprot id: A0A5J6HG69
names: Subunit
messages: Homotetramer.

67345:CP972 RS24925
gene id: 67345:CP972_RS24925
uniprot id: A0A5J6H641
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

67345:CP972 RS16110
gene id: 67345:CP972_RS16110
uniprot id: A0A5J6H6V6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

67345:CP972 RS25320
gene id: 67345:CP972_RS25320
uniprot id: A0A5J6H2N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

67345:CP972 RS27625
gene id: 67345:CP972_RS27625
uniprot id: A0A5J6H744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS15080
gene id: 67345:CP972_RS15080
uniprot id: A0A5J6H3N8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17765
gene id: 67345:CP972_RS17765
uniprot id: A0A5J6H6W1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

67345:CP972 RS28410
gene id: 67345:CP972_RS28410
uniprot id: A0A5J6HC07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS14455
gene id: 67345:CP972_RS14455
uniprot id: A0A5J6H0Y3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

67345:CP972 RS19060
gene id: 67345:CP972_RS19060
uniprot id: A0A5J6H1E4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

67345:CP972 RS14505
gene id: 67345:CP972_RS14505
uniprot id: A0A5J6GWP3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

67345:CP972 RS02180
gene id: 67345:CP972_RS02180
uniprot id: A0A5J6GQP0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

67345:CP972 RS25295
gene id: 67345:CP972_RS25295
uniprot id: A0A5J6H652
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

67345:CP972 RS13545
gene id: 67345:CP972_RS13545
uniprot id: A0A5J6GX90
names: Similarity
messages: Belongs to the UPF0303 family.

67345:CP972 RS12715
gene id: 67345:CP972_RS12715
uniprot id: A0A5J6H045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

67345:CP972 RS21770
gene id: 67345:CP972_RS21770
uniprot id: A0A5J6H4Q0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS20725
gene id: 67345:CP972_RS20725
uniprot id: A0A5J6H0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS08150
gene id: 67345:CP972_RS08150
uniprot id: A0A5J6GXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS27810
gene id: 67345:CP972_RS27810
uniprot id: A0A5J6HAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS21310
gene id: 67345:CP972_RS21310
uniprot id: A0A5J6H4H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

67345:CP972 RS30750
gene id: 67345:CP972_RS30750
uniprot id: A0A5J6HD02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS12890
gene id: 67345:CP972_RS12890
uniprot id: A0A5J6GYQ2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09495
gene id: 67345:CP972_RS09495
uniprot id: A0A5J6H2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67345:CP972 RS22200
gene id: 67345:CP972_RS22200
uniprot id: A0A5J6H5P7
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

67345:CP972 RS06665
gene id: 67345:CP972_RS06665
uniprot id: A0A5J6GT49
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS04825
gene id: 67345:CP972_RS04825
uniprot id: A0A5J6GUM1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

67345:CP972 RS08720
gene id: 67345:CP972_RS08720
uniprot id: A0A5J6GYD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS07720
gene id: 67345:CP972_RS07720
uniprot id: A0A5J6GW97
names: Similarity
messages: Belongs to the peptidase S1 family.

67345:CP972 RS16185
gene id: 67345:CP972_RS16185
uniprot id: A0A5J6H476
names: Similarity
messages: Belongs to the CutC family.

67345:CP972 RS03155
gene id: 67345:CP972_RS03155
uniprot id: A0A5J6GWR8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

67345:CP972 RS24560
gene id: 67345:CP972_RS24560
uniprot id: A0A5J6H2C4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67345:CP972 RS33635
gene id: 67345:CP972_RS33635
uniprot id: A0A5J6HA43
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

67345:CP972 RS07850
gene id: 67345:CP972_RS07850
uniprot id: A0A5J6GUK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

67345:CP972 RS33030
gene id: 67345:CP972_RS33030
uniprot id: A0A5J6HD83
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

67345:CP972 RS09680
gene id: 67345:CP972_RS09680
uniprot id: A0A5J6GYW5
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

67345:CP972 RS17155
gene id: 67345:CP972_RS17155
uniprot id: A0A5J6H0K0
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

67345:CP972 RS29145
gene id: 67345:CP972_RS29145
uniprot id: A0A5J6HBE4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS21195
gene id: 67345:CP972_RS21195
uniprot id: A0A5J6H486
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

67345:CP972 RS11350
gene id: 67345:CP972_RS11350
uniprot id: A0A5J6H1E5
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS14870
gene id: 67345:CP972_RS14870
uniprot id: A0A5J6H151
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17410
gene id: 67345:CP972_RS17410
uniprot id: A0A5J6GXZ9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

67345:CP972 RS00740
gene id: 67345:CP972_RS00740
uniprot id: A0A5J6HEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

67345:CP972 RS21390
gene id: 67345:CP972_RS21390
uniprot id: A0A5J6H8J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

67345:CP972 RS33465
gene id: 67345:CP972_RS33465
uniprot id: A0A5J6HEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67345:CP972 RS06135
gene id: 67345:CP972_RS06135
uniprot id: A0A5J6GWX3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS26490
gene id: 67345:CP972_RS26490
uniprot id: A0A5J6HB62
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25085
gene id: 67345:CP972_RS25085
uniprot id: A0A5J6H604
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS21465
gene id: 67345:CP972_RS21465
uniprot id: A0A5J6H4K3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24360
gene id: 67345:CP972_RS24360
uniprot id: A0A5J6H5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

67345:CP972 RS19955
gene id: 67345:CP972_RS19955
uniprot id: A0A5J6H3J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

67345:CP972 RS16270
gene id: 67345:CP972_RS16270
uniprot id: A0A5J6H053
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

67345:CP972 RS05590
gene id: 67345:CP972_RS05590
uniprot id: A0A5J6GY98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

67345:CP972 RS29480
gene id: 67345:CP972_RS29480
uniprot id: A0A5J6H402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS19780
gene id: 67345:CP972_RS19780
uniprot id: A0A5J6H7S7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17940
gene id: 67345:CP972_RS17940
uniprot id: A0A5J6H2N0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

67345:CP972 RS07230
gene id: 67345:CP972_RS07230
uniprot id: A0A5J6H6A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67345:CP972 RS07535
gene id: 67345:CP972_RS07535
uniprot id: A0A5J6GXJ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS20945
gene id: 67345:CP972_RS20945
uniprot id: A0A5J6H8C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS24085
gene id: 67345:CP972_RS24085
uniprot id: A0A5J6H8A0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

67345:CP972 RS29740
gene id: 67345:CP972_RS29740
uniprot id: A0A5J6H893
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS05700
gene id: 67345:CP972_RS05700
uniprot id: A0A5J6GTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS07200
gene id: 67345:CP972_RS07200
uniprot id: A0A5J6GW05
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS30610
gene id: 67345:CP972_RS30610
uniprot id: A0A5J6H8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS09355
gene id: 67345:CP972_RS09355
uniprot id: A0A5J6GYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

67345:CP972 RS16430
gene id: 67345:CP972_RS16430
uniprot id: A0A5J6H4C4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS07780
gene id: 67345:CP972_RS07780
uniprot id: A0A5J6GYW9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

67345:CP972 RS06785
gene id: 67345:CP972_RS06785
uniprot id: A0A5J6GYV9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS13045
gene id: 67345:CP972_RS13045
uniprot id: A0A5J6H2I4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09385
gene id: 67345:CP972_RS09385
uniprot id: A0A5J6H0E7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

67345:CP972 RS24365
gene id: 67345:CP972_RS24365
uniprot id: A0A5J6H3N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

67345:CP972 RS32785
gene id: 67345:CP972_RS32785
uniprot id: A0A5J6H9Q4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

67345:CP972 RS29000
gene id: 67345:CP972_RS29000
uniprot id: A0A5J6H5S2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

67345:CP972 RS31230
gene id: 67345:CP972_RS31230
uniprot id: A0A5J6HCE0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

67345:CP972 RS30315
gene id: 67345:CP972_RS30315
uniprot id: A0A5J6H6D1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

67345:CP972 RS21515
gene id: 67345:CP972_RS21515
uniprot id: A0A5J6H0V6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

67345:CP972 RS11800
gene id: 67345:CP972_RS11800
uniprot id: A0A5J6H0V9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS13335
gene id: 67345:CP972_RS13335
uniprot id: A0A5J6GX65
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS29025
gene id: 67345:CP972_RS29025
uniprot id: A0A5J6H3U5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67345:CP972 RS20510
gene id: 67345:CP972_RS20510
uniprot id: A0A5J6H738
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS24325
gene id: 67345:CP972_RS24325
uniprot id: A0A5J6H6T8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS31905
gene id: 67345:CP972_RS31905
uniprot id: A0A5J6H967
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS06910
gene id: 67345:CP972_RS06910
uniprot id: A0A5J6GYG9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

67345:CP972 RS21270
gene id: 67345:CP972_RS21270
uniprot id: A0A5J6H445
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

67345:CP972 RS12235
gene id: 67345:CP972_RS12235
uniprot id: A0A5J6GWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

67345:CP972 RS19375
gene id: 67345:CP972_RS19375
uniprot id: A0A5J6GYZ3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

67345:CP972 RS19380
gene id: 67345:CP972_RS19380
uniprot id: A0A5J6H3H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS29110
gene id: 67345:CP972_RS29110
uniprot id: A0A5J6H810
names: Similarity
messages: Belongs to the allantoicase family.

67345:CP972 RS10785
gene id: 67345:CP972_RS10785
uniprot id: A0A5J6HBT4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS10975
gene id: 67345:CP972_RS10975
uniprot id: A0A5J6GW64
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

67345:CP972 RS10190
gene id: 67345:CP972_RS10190
uniprot id: A0A5J6H0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS25290
gene id: 67345:CP972_RS25290
uniprot id: A0A5J6H428
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

67345:CP972 RS30835
gene id: 67345:CP972_RS30835
uniprot id: A0A5J6H8S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

67345:CP972 RS07390
gene id: 67345:CP972_RS07390
uniprot id: A0A5J6GZ57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

67345:CP972 RS18230
gene id: 67345:CP972_RS18230
uniprot id: A0A5J6GZ98
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67345:CP972 RS26345
gene id: 67345:CP972_RS26345
uniprot id: A0A5J6H6Q9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS07195
gene id: 67345:CP972_RS07195
uniprot id: A0A5J6GXD8
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS17605
gene id: 67345:CP972_RS17605
uniprot id: A0A5J6H6S8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS07285
gene id: 67345:CP972_RS07285
uniprot id: A0A5J6GUC8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

67345:CP972 RS05155
gene id: 67345:CP972_RS05155
uniprot id: A0A5J6GWI2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

67345:CP972 RS22130
gene id: 67345:CP972_RS22130
uniprot id: A0A5J6H4I5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS07490
gene id: 67345:CP972_RS07490
uniprot id: A0A5J6GYS0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

67345:CP972 RS16770
gene id: 67345:CP972_RS16770
uniprot id: A0A5J6H220
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS02325
gene id: 67345:CP972_RS02325
uniprot id: A0A5J6GV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS16760
gene id: 67345:CP972_RS16760
uniprot id: A0A5J6GXP5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS01935
gene id: 67345:CP972_RS01935
uniprot id: A0A5J6GSB2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS11830
gene id: 67345:CP972_RS11830
uniprot id: A0A5J6GZT9
names: Similarity
messages: Belongs to the Fur family.

67345:CP972 RS09410
gene id: 67345:CP972_RS09410
uniprot id: A0A5J6GYC4
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS30270
gene id: 67345:CP972_RS30270
uniprot id: A0A5J6HCU2
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

67345:CP972 RS24665
gene id: 67345:CP972_RS24665
uniprot id: A0A5J6H6Z3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

67345:CP972 RS17990
gene id: 67345:CP972_RS17990
uniprot id: A0A5J6H2L5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

67345:CP972 RS26235
gene id: 67345:CP972_RS26235
uniprot id: A0A5J6H6I2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67345:CP972 RS12000
gene id: 67345:CP972_RS12000
uniprot id: A0A5J6GWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

67345:CP972 RS20680
gene id: 67345:CP972_RS20680
uniprot id: A0A5J6H410
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

67345:CP972 RS25390
gene id: 67345:CP972_RS25390
uniprot id: A0A5J6H448
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

67345:CP972 RS09295
gene id: 67345:CP972_RS09295
uniprot id: A0A5J6GX11
names: Similarity
messages: Belongs to the TrpC family.

67345:CP972 RS25670
gene id: 67345:CP972_RS25670
uniprot id: A0A5J6H687
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS30415
gene id: 67345:CP972_RS30415
uniprot id: A0A5J6HC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

67345:CP972 RS02410
gene id: 67345:CP972_RS02410
uniprot id: A0A5J6GSI2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25030
gene id: 67345:CP972_RS25030
uniprot id: A0A5J6H5Y9
names: Cofactor
messages: Binds 1 FAD per subunit.

67345:CP972 RS22220
gene id: 67345:CP972_RS22220
uniprot id: A0A5J6H187
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS25645
gene id: 67345:CP972_RS25645
uniprot id: A0A5J6H920
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

67345:CP972 RS10060
gene id: 67345:CP972_RS10060
uniprot id: A0A5J6H339
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

67345:CP972 RS06395
gene id: 67345:CP972_RS06395
uniprot id: A0A5J6GVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

67345:CP972 RS20245
gene id: 67345:CP972_RS20245
uniprot id: A0A5J6H4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

67345:CP972 RS30000
gene id: 67345:CP972_RS30000
uniprot id: A0A5J6HBU6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08545
gene id: 67345:CP972_RS08545
uniprot id: A0A5J6GZW6
names: Similarity
messages: Belongs to the DapA family.

67345:CP972 RS06470
gene id: 67345:CP972_RS06470
uniprot id: A0A5J6H1H8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

67345:CP972 RS06375
gene id: 67345:CP972_RS06375
uniprot id: A0A5J6GTZ7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

67345:CP972 RS15490
gene id: 67345:CP972_RS15490
uniprot id: A0A5J6GX42
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

67345:CP972 RS15655
gene id: 67345:CP972_RS15655
uniprot id: A0A5J6H2Q2
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS10085
gene id: 67345:CP972_RS10085
uniprot id: A0A5J6GZ28
names: Similarity
messages: Belongs to the ArsC family.

67345:CP972 RS09460
gene id: 67345:CP972_RS09460
uniprot id: A0A5J6GYS6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

67345:CP972 RS14210
gene id: 67345:CP972_RS14210
uniprot id: A0A5J6GZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

67345:CP972 RS08515
gene id: 67345:CP972_RS08515
uniprot id: A0A5J6GY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS12445
gene id: 67345:CP972_RS12445
uniprot id: A0A5J6H494
names: Similarity
messages: Belongs to the LacAB/RpiB family.

67345:CP972 RS24895
gene id: 67345:CP972_RS24895
uniprot id: A0A5J6HAI0
names: Similarity
messages: Belongs to the LOG family.

67345:CP972 RS12495
gene id: 67345:CP972_RS12495
uniprot id: A0A5J6H159
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS06300
gene id: 67345:CP972_RS06300
uniprot id: A0A5J6GX55
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

67345:CP972 RS05275
gene id: 67345:CP972_RS05275
uniprot id: A0A5J6GWS8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

67345:CP972 RS07515
gene id: 67345:CP972_RS07515
uniprot id: A0A5J6GUF5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS00670
gene id: 67345:CP972_RS00670
uniprot id: A0A5J6GW47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS26415
gene id: 67345:CP972_RS26415
uniprot id: A0A5J6H7R9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

67345:CP972 RS02815
gene id: 67345:CP972_RS02815
uniprot id: A0A5J6GS98
names: Similarity
messages: Belongs to the catalase family.

67345:CP972 RS31975
gene id: 67345:CP972_RS31975
uniprot id: A0A5J6H531
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

67345:CP972 RS25255
gene id: 67345:CP972_RS25255
uniprot id: A0A5J6H2A4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

67345:CP972 RS07520
gene id: 67345:CP972_RS07520
uniprot id: A0A5J6HBK2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21550
gene id: 67345:CP972_RS21550
uniprot id: A0A5J6H0M0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

67345:CP972 RS21495
gene id: 67345:CP972_RS21495
uniprot id: A0A5J6H5D1
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS28475
gene id: 67345:CP972_RS28475
uniprot id: A0A5J6HC14
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

67345:CP972 RS32345
gene id: 67345:CP972_RS32345
uniprot id: A0A5J6H588
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

67345:CP972 RS29935
gene id: 67345:CP972_RS29935
uniprot id: A0A5J6HCP3
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

67345:CP972 RS06520
gene id: 67345:CP972_RS06520
uniprot id: A0A5J6GYB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

67345:CP972 RS29980
gene id: 67345:CP972_RS29980
uniprot id: A0A5J6H8C5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS30725
gene id: 67345:CP972_RS30725
uniprot id: A0A5J6H8S1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS26915
gene id: 67345:CP972_RS26915
uniprot id: A0A5J6H6W3
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

67345:CP972 RS21165
gene id: 67345:CP972_RS21165
uniprot id: A0A5J6H0G1
names: Similarity
messages: Belongs to the UPF0336 family.

67345:CP972 RS13550
gene id: 67345:CP972_RS13550
uniprot id: A0A5J6H2S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

67345:CP972 RS21200
gene id: 67345:CP972_RS21200
uniprot id: A0A5J6H427
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS02905
gene id: 67345:CP972_RS02905
uniprot id: A0A5J6GTI9
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

67345:CP972 RS07060
gene id: 67345:CP972_RS07060
uniprot id: A0A5J6GTA4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

67345:CP972 RS24950
gene id: 67345:CP972_RS24950
uniprot id: A0A5J6HAI8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS18065
gene id: 67345:CP972_RS18065
uniprot id: A0A5J6H717
names: Similarity
messages: Belongs to the ParB family.

67345:CP972 RS14495
gene id: 67345:CP972_RS14495
uniprot id: A0A5J6H3D0
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

67345:CP972 RS18045
gene id: 67345:CP972_RS18045
uniprot id: A0A5J6H2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

67345:CP972 RS10255
gene id: 67345:CP972_RS10255
uniprot id: A0A5J6HEH7
names: Similarity
messages: Belongs to the glutamine synthetase family.

67345:CP972 RS07635
gene id: 67345:CP972_RS07635
uniprot id: A0A5J6GUG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS06290
gene id: 67345:CP972_RS06290
uniprot id: A0A5J6GWZ9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

67345:CP972 RS11295
gene id: 67345:CP972_RS11295
uniprot id: A0A5J6GV69
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

67345:CP972 RS25985
gene id: 67345:CP972_RS25985
uniprot id: A0A5J6HAZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

67345:CP972 RS15720
gene id: 67345:CP972_RS15720
uniprot id: A0A5J6GY53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67345:CP972 RS09960
gene id: 67345:CP972_RS09960
uniprot id: A0A5J6GVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

67345:CP972 RS16780
gene id: 67345:CP972_RS16780
uniprot id: A0A5J6HC64
names: Similarity
messages: Belongs to the Fur family.

67345:CP972 RS02320
gene id: 67345:CP972_RS02320
uniprot id: A0A5J6GVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS11825
gene id: 67345:CP972_RS11825
uniprot id: A0A5J6GVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS15085
gene id: 67345:CP972_RS15085
uniprot id: A0A5J6GXW8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06360
gene id: 67345:CP972_RS06360
uniprot id: A0A5J6H1G2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

67345:CP972 RS33785
gene id: 67345:CP972_RS33785
uniprot id: A0A5J6H5X1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

67345:CP972 RS09350
gene id: 67345:CP972_RS09350
uniprot id: A0A5J6GX22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

67345:CP972 RS26290
gene id: 67345:CP972_RS26290
uniprot id: A0A5J6H6P9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

67345:CP972 RS30445
gene id: 67345:CP972_RS30445
uniprot id: A0A5J6H6E5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS33015
gene id: 67345:CP972_RS33015
uniprot id: A0A5J6HFZ4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS18010
gene id: 67345:CP972_RS18010
uniprot id: A0A5J6H707
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

67345:CP972 RS06295
gene id: 67345:CP972_RS06295
uniprot id: A0A5J6GVH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

67345:CP972 RS16545
gene id: 67345:CP972_RS16545
uniprot id: A0A5J6GYH2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

67345:CP972 RS24610
gene id: 67345:CP972_RS24610
uniprot id: A0A5J6HAE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

67345:CP972 RS06570
gene id: 67345:CP972_RS06570
uniprot id: A0A5J6GYC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

67345:CP972 RS25005
gene id: 67345:CP972_RS25005
uniprot id: A0A5J6H273
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS20350
gene id: 67345:CP972_RS20350
uniprot id: A0A5J6H096
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

67345:CP972 RS25875
gene id: 67345:CP972_RS25875
uniprot id: A0A5J6H6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

67345:CP972 RS11080
gene id: 67345:CP972_RS11080
uniprot id: A0A5J6H0K1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67345:CP972 RS05860
gene id: 67345:CP972_RS05860
uniprot id: A0A5J6H173
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

67345:CP972 RS09540
gene id: 67345:CP972_RS09540
uniprot id: A0A5J6GZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

67345:CP972 RS10185
gene id: 67345:CP972_RS10185
uniprot id: A0A5J6GVU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS31090
gene id: 67345:CP972_RS31090
uniprot id: A0A5J6H8V2
names: Similarity
messages: Belongs to the TPP enzyme family.

67345:CP972 RS25285
gene id: 67345:CP972_RS25285
uniprot id: A0A5J6H632
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

67345:CP972 RS06500
gene id: 67345:CP972_RS06500
uniprot id: A0A5J6GX35
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

67345:CP972 RS06390
gene id: 67345:CP972_RS06390
uniprot id: A0A5J6GX19
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

67345:CP972 RS19845
gene id: 67345:CP972_RS19845
uniprot id: A0A5J6H7T3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

67345:CP972 RS06840
gene id: 67345:CP972_RS06840
uniprot id: A0A5J6HE95
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS27225
gene id: 67345:CP972_RS27225
uniprot id: A0A5J6H6Y0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS11990
gene id: 67345:CP972_RS11990
uniprot id: A0A5J6H420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

67345:CP972 RS08370
gene id: 67345:CP972_RS08370
uniprot id: A0A5J6H6C9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS12280
gene id: 67345:CP972_RS12280
uniprot id: A0A5J6GWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS08175
gene id: 67345:CP972_RS08175
uniprot id: A0A5J6GZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67345:CP972 RS11655
gene id: 67345:CP972_RS11655
uniprot id: A0A5J6GZQ5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

67345:CP972 RS26385
gene id: 67345:CP972_RS26385
uniprot id: A0A5J6H356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

67345:CP972 RS09660
gene id: 67345:CP972_RS09660
uniprot id: A0A5J6GVN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

67345:CP972 RS28060
gene id: 67345:CP972_RS28060
uniprot id: A0A5J6H5A4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

67345:CP972 RS32425
gene id: 67345:CP972_RS32425
uniprot id: A0A5J6H9G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

67345:CP972 RS32495
gene id: 67345:CP972_RS32495
uniprot id: A0A5J6H5A7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS25395
gene id: 67345:CP972_RS25395
uniprot id: A0A5J6H668
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

67345:CP972 RS11185
gene id: 67345:CP972_RS11185
uniprot id: A0A5J6GZI1
names: Similarity
messages: Belongs to the CdaR family.

67345:CP972 RS32215
gene id: 67345:CP972_RS32215
uniprot id: A0A5J6HDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

67345:CP972 RS22445
gene id: 67345:CP972_RS22445
uniprot id: A0A5J6H982
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS30475
gene id: 67345:CP972_RS30475
uniprot id: A0A5J6H512
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

67345:CP972 RS11315
gene id: 67345:CP972_RS11315
uniprot id: A0A5J6GZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

67345:CP972 RS25485
gene id: 67345:CP972_RS25485
uniprot id: A0A5J6H8Z4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

67345:CP972 RS30985
gene id: 67345:CP972_RS30985
uniprot id: A0A5J6HA06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

67345:CP972 RS26055
gene id: 67345:CP972_RS26055
uniprot id: A0A5J6H986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

67345:CP972 RS05760
gene id: 67345:CP972_RS05760
uniprot id: A0A5J6GYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

67345:CP972 RS05695
gene id: 67345:CP972_RS05695
uniprot id: A0A5J6H137
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

67345:CP972 RS00705
gene id: 67345:CP972_RS00705
uniprot id: A0A5J6GUH3
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

67345:CP972 RS33630
gene id: 67345:CP972_RS33630
uniprot id: A0A5J6H7X7
names: Similarity
messages: Belongs to the YciI family.

67345:CP972 RS12460
gene id: 67345:CP972_RS12460
uniprot id: A0A5J6H223
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

67345:CP972 RS16000
gene id: 67345:CP972_RS16000
uniprot id: A0A5J6H1J6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS02485
gene id: 67345:CP972_RS02485
uniprot id: A0A5J6H769
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

67345:CP972 RS26835
gene id: 67345:CP972_RS26835
uniprot id: A0A5J6H6Z2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS21735
gene id: 67345:CP972_RS21735
uniprot id: A0A5J6H2G0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

67345:CP972 RS05930
gene id: 67345:CP972_RS05930
uniprot id: A0A5J6GSJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

67345:CP972 RS28380
gene id: 67345:CP972_RS28380
uniprot id: A0A5J6H398
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

67345:CP972 RS21250
gene id: 67345:CP972_RS21250
uniprot id: A0A5J6GZR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

67345:CP972 RS20730
gene id: 67345:CP972_RS20730
uniprot id: A0A5J6GZI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS10310
gene id: 67345:CP972_RS10310
uniprot id: A0A5J6GZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS06120
gene id: 67345:CP972_RS06120
uniprot id: A0A5J6GTV0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS07165
gene id: 67345:CP972_RS07165
uniprot id: A0A5J6GUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS25740
gene id: 67345:CP972_RS25740
uniprot id: A0A5J6HAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

67345:CP972 RS29765
gene id: 67345:CP972_RS29765
uniprot id: A0A5J6H9H9
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS18080
gene id: 67345:CP972_RS18080
uniprot id: A0A5J6GZ79
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

67345:CP972 RS24755
gene id: 67345:CP972_RS24755
uniprot id: A0A5J6H616
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

67345:CP972 RS09510
gene id: 67345:CP972_RS09510
uniprot id: A0A5J6GV91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

67345:CP972 RS15200
gene id: 67345:CP972_RS15200
uniprot id: A0A5J6H5R2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

67345:CP972 RS23760
gene id: 67345:CP972_RS23760
uniprot id: A0A5J6H1N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

67345:CP972 RS27820
gene id: 67345:CP972_RS27820
uniprot id: A0A5J6H2T0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS09615
gene id: 67345:CP972_RS09615
uniprot id: A0A5J6GVB0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

67345:CP972 RS07985
gene id: 67345:CP972_RS07985
uniprot id: A0A5J6GUW1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

67345:CP972 RS33250
gene id: 67345:CP972_RS33250
uniprot id: A0A5J6H5N9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

67345:CP972 RS09335
gene id: 67345:CP972_RS09335
uniprot id: A0A5J6GUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

67345:CP972 RS33040
gene id: 67345:CP972_RS33040
uniprot id: A0A5J6H5K2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

67345:CP972 RS20040
gene id: 67345:CP972_RS20040
uniprot id: A0A5J6H7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS27180
gene id: 67345:CP972_RS27180
uniprot id: A0A5J6H4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS07650
gene id: 67345:CP972_RS07650
uniprot id: A0A5J6GXK9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS14975
gene id: 67345:CP972_RS14975
uniprot id: A0A5J6HC18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

67345:CP972 RS29020
gene id: 67345:CP972_RS29020
uniprot id: A0A5J6HC96
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67345:CP972 RS09490
gene id: 67345:CP972_RS09490
uniprot id: A0A5J6GZV0
names: Similarity
messages: Belongs to the YggT family.

67345:CP972 RS20555
gene id: 67345:CP972_RS20555
uniprot id: A0A5J6H8A6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS16465
gene id: 67345:CP972_RS16465
uniprot id: A0A5J6H320
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS20080
gene id: 67345:CP972_RS20080
uniprot id: A0A5J6H1R7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

67345:CP972 RS20685
gene id: 67345:CP972_RS20685
uniprot id: A0A5J6H3V2
names: Similarity
messages: Belongs to the peptidase A24 family.

67345:CP972 RS18340
gene id: 67345:CP972_RS18340
uniprot id: A0A5J6GZB7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

67345:CP972 RS22380
gene id: 67345:CP972_RS22380
uniprot id: A0A5J6H4M4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

67345:CP972 RS15075
gene id: 67345:CP972_RS15075
uniprot id: A0A5J6GXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS21160
gene id: 67345:CP972_RS21160
uniprot id: A0A5J6H8F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

67345:CP972 RS14945
gene id: 67345:CP972_RS14945
uniprot id: A0A5J6GXV0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS29635
gene id: 67345:CP972_RS29635
uniprot id: A0A5J6H869
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

67345:CP972 RS08575
gene id: 67345:CP972_RS08575
uniprot id: A0A5J6GY58
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS02120
gene id: 67345:CP972_RS02120
uniprot id: A0A5J6GQN0
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

67345:CP972 RS20455
gene id: 67345:CP972_RS20455
uniprot id: A0A5J6H4W5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS11840
gene id: 67345:CP972_RS11840
uniprot id: A0A5J6GY96
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

67345:CP972 RS26335
gene id: 67345:CP972_RS26335
uniprot id: A0A5J6H344
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67345:CP972 RS26535
gene id: 67345:CP972_RS26535
uniprot id: A0A5J6H7T7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

67345:CP972 RS05315
gene id: 67345:CP972_RS05315
uniprot id: A0A5J6GTF9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS26175
gene id: 67345:CP972_RS26175
uniprot id: A0A5J6H6M8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

67345:CP972 RS03790
gene id: 67345:CP972_RS03790
uniprot id: A0A5J6GVW3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS13170
gene id: 67345:CP972_RS13170
uniprot id: A0A5J6GX26
names: Similarity
messages: Belongs to the TPP enzyme family.

67345:CP972 RS04530
gene id: 67345:CP972_RS04530
uniprot id: A0A5J6GW21
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

67345:CP972 RS01300
gene id: 67345:CP972_RS01300
uniprot id: A0A5J6GV46
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS02345
gene id: 67345:CP972_RS02345
uniprot id: A0A5J6GWE3
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS14815
gene id: 67345:CP972_RS14815
uniprot id: A0A5J6GZI2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

67345:CP972 RS09450
gene id: 67345:CP972_RS09450
uniprot id: A0A5J6GV82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67345:CP972 RS05250
gene id: 67345:CP972_RS05250
uniprot id: A0A5J6GTQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS13585
gene id: 67345:CP972_RS13585
uniprot id: A0A5J6GZ09
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17590
gene id: 67345:CP972_RS17590
uniprot id: A0A5J6H0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

67345:CP972 RS29335
gene id: 67345:CP972_RS29335
uniprot id: A0A5J6H4H8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

67345:CP972 RS29715
gene id: 67345:CP972_RS29715
uniprot id: A0A5J6HCK6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

67345:CP972 RS08675
gene id: 67345:CP972_RS08675
uniprot id: A0A5J6GWP2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

67345:CP972 RS30045
gene id: 67345:CP972_RS30045
uniprot id: A0A5J6HCR2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

67345:CP972 RS25210
gene id: 67345:CP972_RS25210
uniprot id: A0A5J6H2M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

67345:CP972 RS19245
gene id: 67345:CP972_RS19245
uniprot id: A0A5J6H5S7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS12015
gene id: 67345:CP972_RS12015
uniprot id: A0A5J6HEL9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

67345:CP972 RS19455
gene id: 67345:CP972_RS19455
uniprot id: A0A5J6H3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

67345:CP972 RS08405
gene id: 67345:CP972_RS08405
uniprot id: A0A5J6GY32
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

67345:CP972 RS13305
gene id: 67345:CP972_RS13305
uniprot id: A0A5J6GYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS09235
gene id: 67345:CP972_RS09235
uniprot id: A0A5J6GYN7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19950
gene id: 67345:CP972_RS19950
uniprot id: A0A5J6H3P9
names: Similarity
messages: Belongs to the UPF0145 family.

67345:CP972 RS15225
gene id: 67345:CP972_RS15225
uniprot id: A0A5J6GX05
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25000
gene id: 67345:CP972_RS25000
uniprot id: A0A5J6HAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

67345:CP972 RS02500
gene id: 67345:CP972_RS02500
uniprot id: A0A5J6GQU1
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS08705
gene id: 67345:CP972_RS08705
uniprot id: A0A5J6H006
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

67345:CP972 RS18295
gene id: 67345:CP972_RS18295
uniprot id: A0A5J6H5C7
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

67345:CP972 RS15880
gene id: 67345:CP972_RS15880
uniprot id: A0A5J6H1I3
names: Similarity
messages: Belongs to the citrate synthase family.

67345:CP972 RS24530
gene id: 67345:CP972_RS24530
uniprot id: A0A5J6H3Q2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67345:CP972 RS04560
gene id: 67345:CP972_RS04560
uniprot id: A0A5J6GXQ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67345:CP972 RS09520
gene id: 67345:CP972_RS09520
uniprot id: A0A5J6GYT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS05400
gene id: 67345:CP972_RS05400
uniprot id: A0A5J6H0Y0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

67345:CP972 RS14285
gene id: 67345:CP972_RS14285
uniprot id: A0A5J6H276
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67345:CP972 RS22600
gene id: 67345:CP972_RS22600
uniprot id: A0A5J6H1E8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25745
gene id: 67345:CP972_RS25745
uniprot id: A0A5J6H2G4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

67345:CP972 RS02445
gene id: 67345:CP972_RS02445
uniprot id: A0A5J6GV34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS08875
gene id: 67345:CP972_RS08875
uniprot id: A0A5J6GUZ7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS22950
gene id: 67345:CP972_RS22950
uniprot id: A0A5J6H1K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

67345:CP972 RS16945
gene id: 67345:CP972_RS16945
uniprot id: A0A5J6GXS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

67345:CP972 RS12375
gene id: 67345:CP972_RS12375
uniprot id: A0A5J6H012
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

67345:CP972 RS10810
gene id: 67345:CP972_RS10810
uniprot id: A0A5J6GXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS23105
gene id: 67345:CP972_RS23105
uniprot id: A0A5J6H319
names: Similarity
messages: Belongs to the peptidase S8 family.

67345:CP972 RS02175
gene id: 67345:CP972_RS02175
uniprot id: A0A5J6GRZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

67345:CP972 RS06350
gene id: 67345:CP972_RS06350
uniprot id: A0A5J6GX66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

67345:CP972 RS26950
gene id: 67345:CP972_RS26950
uniprot id: A0A5J6H2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

67345:CP972 RS21520
gene id: 67345:CP972_RS21520
uniprot id: A0A5J6GZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

67345:CP972 RS10010
gene id: 67345:CP972_RS10010
uniprot id: A0A5J6GVR8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS15620
gene id: 67345:CP972_RS15620
uniprot id: A0A5J6H3X0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS26655
gene id: 67345:CP972_RS26655
uniprot id: A0A5J6H4P3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

67345:CP972 RS25800
gene id: 67345:CP972_RS25800
uniprot id: A0A5J6H949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

67345:CP972 RS27035
gene id: 67345:CP972_RS27035
uniprot id: A0A5J6H2Z1
names: Similarity
messages: Belongs to the histone deacetylase family.

67345:CP972 RS23060
gene id: 67345:CP972_RS23060
uniprot id: A0A5J6H9G5
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

67345:CP972 RS23210
gene id: 67345:CP972_RS23210
uniprot id: A0A5J6H500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS20595
gene id: 67345:CP972_RS20595
uniprot id: A0A5J6H851
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09895
gene id: 67345:CP972_RS09895
uniprot id: A0A5J6GVQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

67345:CP972 RS08075
gene id: 67345:CP972_RS08075
uniprot id: A0A5J6GWE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

67345:CP972 RS21010
gene id: 67345:CP972_RS21010
uniprot id: A0A5J6H0E1
names: Similarity
messages: Belongs to the UPF0234 family.

67345:CP972 RS18225
gene id: 67345:CP972_RS18225
uniprot id: A0A5J6H751
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS07465
gene id: 67345:CP972_RS07465
uniprot id: A0A5J6GXV5
names: Similarity
messages: Belongs to the UPF0225 family.

67345:CP972 RS08960
gene id: 67345:CP972_RS08960
uniprot id: A0A5J6GZL8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS27575
gene id: 67345:CP972_RS27575
uniprot id: A0A5J6HBL6
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

67345:CP972 RS08655
gene id: 67345:CP972_RS08655
uniprot id: A0A5J6GUX0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

67345:CP972 RS32975
gene id: 67345:CP972_RS32975
uniprot id: A0A5J6H6M3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08085
gene id: 67345:CP972_RS08085
uniprot id: A0A5J6GXY8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS24600
gene id: 67345:CP972_RS24600
uniprot id: A0A5J6H6Y4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

67345:CP972 RS05410
gene id: 67345:CP972_RS05410
uniprot id: A0A5J6GY64
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS13805
gene id: 67345:CP972_RS13805
uniprot id: A0A5J6H0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

67345:CP972 RS09480
gene id: 67345:CP972_RS09480
uniprot id: A0A5J6GX41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

67345:CP972 RS33290
gene id: 67345:CP972_RS33290
uniprot id: A0A5J6HDC5
names: Similarity
messages: Belongs to the peptidase A31 family.

67345:CP972 RS18405
gene id: 67345:CP972_RS18405
uniprot id: A0A5J6H5F1
names: Similarity
messages: Belongs to the SCO1/2 family.

67345:CP972 RS06925
gene id: 67345:CP972_RS06925
uniprot id: A0A5J6GYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

67345:CP972 RS21360
gene id: 67345:CP972_RS21360
uniprot id: A0A5J6H4I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

67345:CP972 RS20095
gene id: 67345:CP972_RS20095
uniprot id: A0A5J6H7X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS27410
gene id: 67345:CP972_RS27410
uniprot id: A0A5J6H791
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

67345:CP972 RS14780
gene id: 67345:CP972_RS14780
uniprot id: A0A5J6GXS0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS06420
gene id: 67345:CP972_RS06420
uniprot id: A0A5J6GYP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

67345:CP972 RS09215
gene id: 67345:CP972_RS09215
uniprot id: A0A5J6GVJ1
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS22030
gene id: 67345:CP972_RS22030
uniprot id: A0A5J6H0T6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21430
gene id: 67345:CP972_RS21430
uniprot id: A0A5J6H473
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

67345:CP972 RS02130
gene id: 67345:CP972_RS02130
uniprot id: A0A5J6GV02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

67345:CP972 RS22075
gene id: 67345:CP972_RS22075
uniprot id: A0A5J6H927
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

67345:CP972 RS10905
gene id: 67345:CP972_RS10905
uniprot id: A0A5J6GW53
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

67345:CP972 RS24305
gene id: 67345:CP972_RS24305
uniprot id: A0A5J6H5I9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

67345:CP972 RS07865
gene id: 67345:CP972_RS07865
uniprot id: A0A5J6GY20
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS11480
gene id: 67345:CP972_RS11480
uniprot id: A0A5J6GZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS31845
gene id: 67345:CP972_RS31845
uniprot id: A0A5J6H8X5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS26580
gene id: 67345:CP972_RS26580
uniprot id: A0A5J6H6R2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

67345:CP972 RS00225
gene id: 67345:CP972_RS00225
uniprot id: A0A5J6GSH6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

67345:CP972 RS06340
gene id: 67345:CP972_RS06340
uniprot id: A0A5J6GX10
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

67345:CP972 RS05980
gene id: 67345:CP972_RS05980
uniprot id: A0A5J6GTS9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

67345:CP972 RS12290
gene id: 67345:CP972_RS12290
uniprot id: A0A5J6GWN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

67345:CP972 RS07595
gene id: 67345:CP972_RS07595
uniprot id: A0A5J6GXK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS20985
gene id: 67345:CP972_RS20985
uniprot id: A0A5J6H259
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS23745
gene id: 67345:CP972_RS23745
uniprot id: A0A5J6H6J5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

67345:CP972 RS18300
gene id: 67345:CP972_RS18300
uniprot id: A0A5J6GZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

67345:CP972 RS21450
gene id: 67345:CP972_RS21450
uniprot id: A0A5J6H6X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

67345:CP972 RS29900
gene id: 67345:CP972_RS29900
uniprot id: A0A5J6H4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS08070
gene id: 67345:CP972_RS08070
uniprot id: A0A5J6GXS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

67345:CP972 RS03580
gene id: 67345:CP972_RS03580
uniprot id: A0A5J6GR75
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS28285
gene id: 67345:CP972_RS28285
uniprot id: A0A5J6H7G5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

67345:CP972 RS32285
gene id: 67345:CP972_RS32285
uniprot id: A0A5J6H7P2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS03170
gene id: 67345:CP972_RS03170
uniprot id: A0A5J6GX43
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS14705
gene id: 67345:CP972_RS14705
uniprot id: A0A5J6GZG2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67345:CP972 RS29255
gene id: 67345:CP972_RS29255
uniprot id: A0A5J6HCD6
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS33265
gene id: 67345:CP972_RS33265
uniprot id: A0A5J6H7R6
names: Similarity
messages: Belongs to the HypD family.

67345:CP972 RS03145
gene id: 67345:CP972_RS03145
uniprot id: A0A5J6GTN4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS32795
gene id: 67345:CP972_RS32795
uniprot id: A0A5J6HDY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

67345:CP972 RS02340
gene id: 67345:CP972_RS02340
uniprot id: A0A5J6GUZ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

67345:CP972 RS19965
gene id: 67345:CP972_RS19965
uniprot id: A0A5J6HCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

67345:CP972 RS25715
gene id: 67345:CP972_RS25715
uniprot id: A0A5J6H6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

67345:CP972 RS06015
gene id: 67345:CP972_RS06015
uniprot id: A0A5J6GVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

67345:CP972 RS23395
gene id: 67345:CP972_RS23395
uniprot id: A0A5J6H6D2
names: Similarity
messages: Belongs to the LOG family.

67345:CP972 RS11255
gene id: 67345:CP972_RS11255
uniprot id: A0A5J6HAX7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS06030
gene id: 67345:CP972_RS06030
uniprot id: A0A5J6H1A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

67345:CP972 RS12220
gene id: 67345:CP972_RS12220
uniprot id: A0A5J6H454
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS19980
gene id: 67345:CP972_RS19980
uniprot id: A0A5J6H7V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

67345:CP972 RS15305
gene id: 67345:CP972_RS15305
uniprot id: A0A5J6H2K9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS13875
gene id: 67345:CP972_RS13875
uniprot id: A0A5J6H548
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

67345:CP972 RS20255
gene id: 67345:CP972_RS20255
uniprot id: A0A5J6H034
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS08420
gene id: 67345:CP972_RS08420
uniprot id: A0A5J6GV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

67345:CP972 RS08255
gene id: 67345:CP972_RS08255
uniprot id: A0A5J6GY75
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS26050
gene id: 67345:CP972_RS26050
uniprot id: A0A5J6H2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

67345:CP972 RS21795
gene id: 67345:CP972_RS21795
uniprot id: A0A5J6H0Q5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

67345:CP972 RS21400
gene id: 67345:CP972_RS21400
uniprot id: A0A5J6H6V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

67345:CP972 RS09045
gene id: 67345:CP972_RS09045
uniprot id: A0A5J6GU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

67345:CP972 RS03975
gene id: 67345:CP972_RS03975
uniprot id: A0A5J6GT42
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

67345:CP972 RS21370
gene id: 67345:CP972_RS21370
uniprot id: A0A5J6H2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS28505
gene id: 67345:CP972_RS28505
uniprot id: A0A5J6H3B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

67345:CP972 RS21275
gene id: 67345:CP972_RS21275
uniprot id: A0A5J6H585
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

67345:CP972 RS17315
gene id: 67345:CP972_RS17315
uniprot id: A0A5J6H4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

67345:CP972 RS10230
gene id: 67345:CP972_RS10230
uniprot id: A0A5J6GXI1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

67345:CP972 RS28345
gene id: 67345:CP972_RS28345
uniprot id: A0A5J6H7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS08740
gene id: 67345:CP972_RS08740
uniprot id: A0A5J6GZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS24740
gene id: 67345:CP972_RS24740
uniprot id: A0A5J6H8L2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

67345:CP972 RS08330
gene id: 67345:CP972_RS08330
uniprot id: A0A5J6GXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

67345:CP972 RS05065
gene id: 67345:CP972_RS05065
uniprot id: A0A5J6H671
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS25525
gene id: 67345:CP972_RS25525
uniprot id: A0A5J6HAS9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS22825
gene id: 67345:CP972_RS22825
uniprot id: A0A5J6HFE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS06640
gene id: 67345:CP972_RS06640
uniprot id: A0A5J6H1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS05705
gene id: 67345:CP972_RS05705
uniprot id: A0A5J6GYA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

67345:CP972 RS23415
gene id: 67345:CP972_RS23415
uniprot id: A0A5J6H1T2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS15025
gene id: 67345:CP972_RS15025
uniprot id: A0A5J6H3M5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

67345:CP972 RS13760
gene id: 67345:CP972_RS13760
uniprot id: A0A5J6GXB0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06430
gene id: 67345:CP972_RS06430
uniprot id: A0A5J6GST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

67345:CP972 RS08260
gene id: 67345:CP972_RS08260
uniprot id: A0A5J6GXV6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

67345:CP972 RS14315
gene id: 67345:CP972_RS14315
uniprot id: A0A5J6GWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

67345:CP972 RS00330
gene id: 67345:CP972_RS00330
uniprot id: A0A5J6GUG3
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS25050
gene id: 67345:CP972_RS25050
uniprot id: A0A5J6HAK3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS26100
gene id: 67345:CP972_RS26100
uniprot id: A0A5J6H2L3
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS10055
gene id: 67345:CP972_RS10055
uniprot id: A0A5J6H042
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS16065
gene id: 67345:CP972_RS16065
uniprot id: A0A5J6H1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

67345:CP972 RS18100
gene id: 67345:CP972_RS18100
uniprot id: A0A5J6H106
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08805
gene id: 67345:CP972_RS08805
uniprot id: A0A5J6H2I6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

67345:CP972 RS26770
gene id: 67345:CP972_RS26770
uniprot id: A0A5J6H275
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS26855
gene id: 67345:CP972_RS26855
uniprot id: A0A5J6H7Y8
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

67345:CP972 RS10350
gene id: 67345:CP972_RS10350
uniprot id: A0A5J6GYU6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS23705
gene id: 67345:CP972_RS23705
uniprot id: A0A5J6H0W2
names: Similarity
messages: Belongs to the peptidase S16 family.

67345:CP972 RS17545
gene id: 67345:CP972_RS17545
uniprot id: A0A5J6H2A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

67345:CP972 RS07745
gene id: 67345:CP972_RS07745
uniprot id: A0A5J6GZB3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09230
gene id: 67345:CP972_RS09230
uniprot id: A0A5J6GUB7
names: Similarity
messages: Belongs to the glutamate synthase family.

67345:CP972 RS31635
gene id: 67345:CP972_RS31635
uniprot id: A0A5J6HCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS20345
gene id: 67345:CP972_RS20345
uniprot id: A0A5J6H6D8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

67345:CP972 RS25105
gene id: 67345:CP972_RS25105
uniprot id: A0A5J6H770
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS24370
gene id: 67345:CP972_RS24370
uniprot id: A0A5J6H5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

67345:CP972 RS24210
gene id: 67345:CP972_RS24210
uniprot id: A0A5J6H1U9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS10380
gene id: 67345:CP972_RS10380
uniprot id: A0A5J6GVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

67345:CP972 RS20525
gene id: 67345:CP972_RS20525
uniprot id: A0A5J6H845
names: Similarity
messages: Belongs to the CsoR family.

67345:CP972 RS30405
gene id: 67345:CP972_RS30405
uniprot id: A0A5J6HCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

67345:CP972 RS24715
gene id: 67345:CP972_RS24715
uniprot id: A0A5J6H3T2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS02960
gene id: 67345:CP972_RS02960
uniprot id: A0A5J6GTK1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

67345:CP972 RS16950
gene id: 67345:CP972_RS16950
uniprot id: A0A5J6H2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

67345:CP972 RS07795
gene id: 67345:CP972_RS07795
uniprot id: A0A5J6GZC4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

67345:CP972 RS09130
gene id: 67345:CP972_RS09130
uniprot id: A0A5J6GYI0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

67345:CP972 RS14980
gene id: 67345:CP972_RS14980
uniprot id: A0A5J6H1D8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

67345:CP972 RS08570
gene id: 67345:CP972_RS08570
uniprot id: A0A5J6GWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS30730
gene id: 67345:CP972_RS30730
uniprot id: A0A5J6H6J3
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

67345:CP972 RS08035
gene id: 67345:CP972_RS08035
uniprot id: A0A5J6H282
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67345:CP972 RS09860
gene id: 67345:CP972_RS09860
uniprot id: A0A5J6GYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

67345:CP972 RS12170
gene id: 67345:CP972_RS12170
uniprot id: A0A5J6GWL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS10285
gene id: 67345:CP972_RS10285
uniprot id: A0A5J6GUS4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06140
gene id: 67345:CP972_RS06140
uniprot id: A0A5J6GVE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

67345:CP972 RS09730
gene id: 67345:CP972_RS09730
uniprot id: A0A5J6GUI3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS12895
gene id: 67345:CP972_RS12895
uniprot id: A0A5J6H091
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS15685
gene id: 67345:CP972_RS15685
uniprot id: A0A5J6H1L6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

67345:CP972 RS11720
gene id: 67345:CP972_RS11720
uniprot id: A0A5J6GZR6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

67345:CP972 RS12270
gene id: 67345:CP972_RS12270
uniprot id: A0A5J6H123
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

67345:CP972 RS02095
gene id: 67345:CP972_RS02095
uniprot id: A0A5J6GWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67345:CP972 RS32195
gene id: 67345:CP972_RS32195
uniprot id: A0A5J6H784
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS22015
gene id: 67345:CP972_RS22015
uniprot id: A0A5J6H4G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS17645
gene id: 67345:CP972_RS17645
uniprot id: A0A5J6H2H7
names: Similarity
messages: Belongs to the peptidase S11 family.

67345:CP972 RS18605
gene id: 67345:CP972_RS18605
uniprot id: A0A5J6H7A8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

67345:CP972 RS12885
gene id: 67345:CP972_RS12885
uniprot id: A0A5J6H079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

67345:CP972 RS32730
gene id: 67345:CP972_RS32730
uniprot id: A0A5J6H9P3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

67345:CP972 RS11140
gene id: 67345:CP972_RS11140
uniprot id: A0A5J6GXX3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS20765
gene id: 67345:CP972_RS20765
uniprot id: A0A5J6H0A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS22410
gene id: 67345:CP972_RS22410
uniprot id: A0A5J6H0A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

67345:CP972 RS26945
gene id: 67345:CP972_RS26945
uniprot id: A0A5J6HBR7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

67345:CP972 RS14765
gene id: 67345:CP972_RS14765
uniprot id: A0A5J6H133
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS10155
gene id: 67345:CP972_RS10155
uniprot id: A0A5J6H8M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS22545
gene id: 67345:CP972_RS22545
uniprot id: A0A5J6H1D9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

67345:CP972 RS25920
gene id: 67345:CP972_RS25920
uniprot id: A0A5J6H1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

67345:CP972 RS27875
gene id: 67345:CP972_RS27875
uniprot id: A0A5J6H7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS08715
gene id: 67345:CP972_RS08715
uniprot id: A0A5J6GU31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

67345:CP972 RS01040
gene id: 67345:CP972_RS01040
uniprot id: A0A5J6HA91
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

67345:CP972 RS29620
gene id: 67345:CP972_RS29620
uniprot id: A0A5J6H875
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS27300
gene id: 67345:CP972_RS27300
uniprot id: A0A5J6H4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

67345:CP972 RS02070
gene id: 67345:CP972_RS02070
uniprot id: A0A5J6GVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

67345:CP972 RS18015
gene id: 67345:CP972_RS18015
uniprot id: A0A5J6GZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

67345:CP972 RS13190
gene id: 67345:CP972_RS13190
uniprot id: A0A5J6GYU9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

67345:CP972 RS12775
gene id: 67345:CP972_RS12775
uniprot id: A0A5J6H056
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

67345:CP972 RS06325
gene id: 67345:CP972_RS06325
uniprot id: A0A5J6GTY6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24630
gene id: 67345:CP972_RS24630
uniprot id: A0A5J6H2D1
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS22475
gene id: 67345:CP972_RS22475
uniprot id: A0A5J6H1C8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08525
gene id: 67345:CP972_RS08525
uniprot id: A0A5J6GZF1
names: Similarity
messages: Belongs to the DapA family.

67345:CP972 RS26425
gene id: 67345:CP972_RS26425
uniprot id: A0A5J6H2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67345:CP972 RS29425
gene id: 67345:CP972_RS29425
uniprot id: A0A5J6H866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS06760
gene id: 67345:CP972_RS06760
uniprot id: A0A5J6GVT1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS26495
gene id: 67345:CP972_RS26495
uniprot id: A0A5J6H2S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS31435
gene id: 67345:CP972_RS31435
uniprot id: A0A5J6H930
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

67345:CP972 RS07910
gene id: 67345:CP972_RS07910
uniprot id: A0A5J6GUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS21235
gene id: 67345:CP972_RS21235
uniprot id: A0A5J6H6S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

67345:CP972 RS16155
gene id: 67345:CP972_RS16155
uniprot id: A0A5J6H2X7
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

67345:CP972 RS01865
gene id: 67345:CP972_RS01865
uniprot id: A0A5J6GZ89
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

67345:CP972 RS18055
gene id: 67345:CP972_RS18055
uniprot id: A0A5J6H2P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

67345:CP972 RS32765
gene id: 67345:CP972_RS32765
uniprot id: A0A5J6H5F3
names: Similarity
messages: Belongs to the peptidase S1 family.

67345:CP972 RS17625
gene id: 67345:CP972_RS17625
uniprot id: A0A5J6GY40
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

67345:CP972 RS11015
gene id: 67345:CP972_RS11015
uniprot id: A0A5J6H0J1
names: Similarity
messages: Belongs to the PrpD family.

67345:CP972 RS11920
gene id: 67345:CP972_RS11920
uniprot id: A0A5J6HBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

67345:CP972 RS20800
gene id: 67345:CP972_RS20800
uniprot id: A0A5J6H3X7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS07485
gene id: 67345:CP972_RS07485
uniprot id: A0A5J6GXP4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS01265
gene id: 67345:CP972_RS01265
uniprot id: A0A5J6GZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS16965
gene id: 67345:CP972_RS16965
uniprot id: A0A5J6H0H3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS29490
gene id: 67345:CP972_RS29490
uniprot id: A0A5J6H865
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

67345:CP972 RS03285
gene id: 67345:CP972_RS03285
uniprot id: A0A5J6HA78
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

67345:CP972 RS19290
gene id: 67345:CP972_RS19290
uniprot id: A0A5J6H7L6
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS30200
gene id: 67345:CP972_RS30200
uniprot id: A0A5J6H9P7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

67345:CP972 RS25885
gene id: 67345:CP972_RS25885
uniprot id: A0A5J6H4D1
names: Similarity
messages: Belongs to the peptidase M16 family.

67345:CP972 RS13450
gene id: 67345:CP972_RS13450
uniprot id: A0A5J6H0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS20420
gene id: 67345:CP972_RS20420
uniprot id: A0A5J6H6F0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS20960
gene id: 67345:CP972_RS20960
uniprot id: A0A5J6H0K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS13520
gene id: 67345:CP972_RS13520
uniprot id: A0A5J6H0J0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

67345:CP972 RS04875
gene id: 67345:CP972_RS04875
uniprot id: A0A5J6GUN3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

67345:CP972 RS24270
gene id: 67345:CP972_RS24270
uniprot id: A0A5J6H6S9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

67345:CP972 RS15205
gene id: 67345:CP972_RS15205
uniprot id: A0A5J6HB48
names: Similarity
messages: Belongs to the UDPGP type 2 family.

67345:CP972 RS09795
gene id: 67345:CP972_RS09795
uniprot id: A0A5J6GUJ2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS18175
gene id: 67345:CP972_RS18175
uniprot id: A0A5J6H741
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

67345:CP972 RS00660
gene id: 67345:CP972_RS00660
uniprot id: A0A5J6GYW8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06795
gene id: 67345:CP972_RS06795
uniprot id: A0A5J6GT63
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS21970
gene id: 67345:CP972_RS21970
uniprot id: A0A5J6H0S7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS30880
gene id: 67345:CP972_RS30880
uniprot id: A0A5J6H4M1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67345:CP972 RS15895
gene id: 67345:CP972_RS15895
uniprot id: A0A5J6GY85
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS18365
gene id: 67345:CP972_RS18365
uniprot id: A0A5J6H316
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS16490
gene id: 67345:CP972_RS16490
uniprot id: A0A5J6GXK3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

67345:CP972 RS27685
gene id: 67345:CP972_RS27685
uniprot id: A0A5J6H7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

67345:CP972 RS05425
gene id: 67345:CP972_RS05425
uniprot id: A0A5J6GWW1
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS29615
gene id: 67345:CP972_RS29615
uniprot id: A0A5J6H422
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

67345:CP972 RS25405
gene id: 67345:CP972_RS25405
uniprot id: A0A5J6HBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

67345:CP972 RS03000
gene id: 67345:CP972_RS03000
uniprot id: A0A5J6GR09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS33230
gene id: 67345:CP972_RS33230
uniprot id: A0A5J6HE58
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

67345:CP972 RS09970
gene id: 67345:CP972_RS09970
uniprot id: A0A5J6GZ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

67345:CP972 RS09940
gene id: 67345:CP972_RS09940
uniprot id: A0A5J6H022
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

67345:CP972 RS02420
gene id: 67345:CP972_RS02420
uniprot id: A0A5J6GS41
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

67345:CP972 RS05085
gene id: 67345:CP972_RS05085
uniprot id: A0A5J6GS37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

67345:CP972 RS08820
gene id: 67345:CP972_RS08820
uniprot id: A0A5J6GUZ0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

67345:CP972 RS08800
gene id: 67345:CP972_RS08800
uniprot id: A0A5J6GZJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS15990
gene id: 67345:CP972_RS15990
uniprot id: A0A5J6H013
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS30500
gene id: 67345:CP972_RS30500
uniprot id: A0A5J6H8L8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

67345:CP972 RS31795
gene id: 67345:CP972_RS31795
uniprot id: A0A5J6HDH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

67345:CP972 RS02630
gene id: 67345:CP972_RS02630
uniprot id: A0A5J6GTF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

67345:CP972 RS07080
gene id: 67345:CP972_RS07080
uniprot id: A0A5J6GXI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

67345:CP972 RS30350
gene id: 67345:CP972_RS30350
uniprot id: A0A5J6H4F2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

67345:CP972 RS05335
gene id: 67345:CP972_RS05335
uniprot id: A0A5J6GUW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

67345:CP972 RS19820
gene id: 67345:CP972_RS19820
uniprot id: A0A5J6H3N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

67345:CP972 RS22540
gene id: 67345:CP972_RS22540
uniprot id: A0A5J6H7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS03980
gene id: 67345:CP972_RS03980
uniprot id: A0A5J6GXH6
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS14165
gene id: 67345:CP972_RS14165
uniprot id: A0A5J6H367
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS20240
gene id: 67345:CP972_RS20240
uniprot id: A0A5J6H3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS33285
gene id: 67345:CP972_RS33285
uniprot id: A0A5J6H5P6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

67345:CP972 RS25565
gene id: 67345:CP972_RS25565
uniprot id: A0A5J6H475
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS13890
gene id: 67345:CP972_RS13890
uniprot id: A0A5J6GXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

67345:CP972 RS00610
gene id: 67345:CP972_RS00610
uniprot id: A0A5J6GUI9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

67345:CP972 RS25380
gene id: 67345:CP972_RS25380
uniprot id: A0A5J6H689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

67345:CP972 RS31705
gene id: 67345:CP972_RS31705
uniprot id: A0A5J6H975
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67345:CP972 RS04630
gene id: 67345:CP972_RS04630
uniprot id: A0A5J6GW43
names: Similarity
messages: Belongs to the CdaR family.

67345:CP972 RS21585
gene id: 67345:CP972_RS21585
uniprot id: A0A5J6H498
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

67345:CP972 RS02880
gene id: 67345:CP972_RS02880
uniprot id: A0A5J6GSA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS17275
gene id: 67345:CP972_RS17275
uniprot id: A0A5J6GXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

67345:CP972 RS10035
gene id: 67345:CP972_RS10035
uniprot id: A0A5J6GZ20
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

67345:CP972 RS19320
gene id: 67345:CP972_RS19320
uniprot id: A0A5J6GYY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

67345:CP972 RS17925
gene id: 67345:CP972_RS17925
uniprot id: A0A5J6H2T8
names: Similarity
messages: Belongs to the UPF0749 family.

67345:CP972 RS06915
gene id: 67345:CP972_RS06915
uniprot id: A0A5J6H1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

67345:CP972 RS32690
gene id: 67345:CP972_RS32690
uniprot id: A0A5J6H5E7
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS07300
gene id: 67345:CP972_RS07300
uniprot id: A0A5J6GXS8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

67345:CP972 RS05255
gene id: 67345:CP972_RS05255
uniprot id: A0A5J6GY38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS20185
gene id: 67345:CP972_RS20185
uniprot id: A0A5J6H1T4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

67345:CP972 RS28690
gene id: 67345:CP972_RS28690
uniprot id: A0A5J6H465
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

67345:CP972 RS14920
gene id: 67345:CP972_RS14920
uniprot id: A0A5J6GZK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

67345:CP972 RS24625
gene id: 67345:CP972_RS24625
uniprot id: A0A5J6H8I9
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS31300
gene id: 67345:CP972_RS31300
uniprot id: A0A5J6H5E6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

67345:CP972 RS09780
gene id: 67345:CP972_RS09780
uniprot id: A0A5J6HAT4
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS32630
gene id: 67345:CP972_RS32630
uniprot id: A0A5J6HDV2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS13240
gene id: 67345:CP972_RS13240
uniprot id: A0A5J6H0I1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

67345:CP972 RS31340
gene id: 67345:CP972_RS31340
uniprot id: A0A5J6HD97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS03670
gene id: 67345:CP972_RS03670
uniprot id: A0A5J6GVU5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21365
gene id: 67345:CP972_RS21365
uniprot id: A0A5J6H457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

67345:CP972 RS08810
gene id: 67345:CP972_RS08810
uniprot id: A0A5J6GVC6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

67345:CP972 RS21190
gene id: 67345:CP972_RS21190
uniprot id: A0A5J6GZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

67345:CP972 RS20675
gene id: 67345:CP972_RS20675
uniprot id: A0A5J6GZI0
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS05360
gene id: 67345:CP972_RS05360
uniprot id: A0A5J6GY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67345:CP972 RS29080
gene id: 67345:CP972_RS29080
uniprot id: A0A5J6HCA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS18140
gene id: 67345:CP972_RS18140
uniprot id: A0A5J6GZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

67345:CP972 RS18305
gene id: 67345:CP972_RS18305
uniprot id: A0A5J6GYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

67345:CP972 RS18390
gene id: 67345:CP972_RS18390
uniprot id: A0A5J6H3Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

67345:CP972 RS11275
gene id: 67345:CP972_RS11275
uniprot id: A0A5J6H3P3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09765
gene id: 67345:CP972_RS09765
uniprot id: A0A5J6HB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

67345:CP972 RS07380
gene id: 67345:CP972_RS07380
uniprot id: A0A5J6H1X0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

67345:CP972 RS17305
gene id: 67345:CP972_RS17305
uniprot id: A0A5J6H6M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

67345:CP972 RS18090
gene id: 67345:CP972_RS18090
uniprot id: A0A5J6H2W9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS07585
gene id: 67345:CP972_RS07585
uniprot id: A0A5J6GTL4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

67345:CP972 RS20165
gene id: 67345:CP972_RS20165
uniprot id: A0A5J6H061
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS21435
gene id: 67345:CP972_RS21435
uniprot id: A0A5J6H5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

67345:CP972 RS22280
gene id: 67345:CP972_RS22280
uniprot id: A0A5J6H077
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS31710
gene id: 67345:CP972_RS31710
uniprot id: A0A5J6H709
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67345:CP972 RS00315
gene id: 67345:CP972_RS00315
uniprot id: A0A5J6GRB7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS26850
gene id: 67345:CP972_RS26850
uniprot id: A0A5J6H6V4
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS21535
gene id: 67345:CP972_RS21535
uniprot id: A0A5J6H2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

67345:CP972 RS08015
gene id: 67345:CP972_RS08015
uniprot id: A0A5J6GWE0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

67345:CP972 RS25215
gene id: 67345:CP972_RS25215
uniprot id: A0A5J6H1I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

67345:CP972 RS12180
gene id: 67345:CP972_RS12180
uniprot id: A0A5J6H026
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

67345:CP972 RS27175
gene id: 67345:CP972_RS27175
uniprot id: A0A5J6H6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS19100
gene id: 67345:CP972_RS19100
uniprot id: A0A5J6GYU8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

67345:CP972 RS02805
gene id: 67345:CP972_RS02805
uniprot id: A0A5J6GSN6
names: Similarity
messages: Belongs to the peptidase S1 family.

67345:CP972 RS33140
gene id: 67345:CP972_RS33140
uniprot id: A0A5J6HD98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

67345:CP972 RS23370
gene id: 67345:CP972_RS23370
uniprot id: A0A5J6H0Q2
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

67345:CP972 RS25445
gene id: 67345:CP972_RS25445
uniprot id: A0A5J6H698
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

67345:CP972 RS26870
gene id: 67345:CP972_RS26870
uniprot id: A0A5J6H2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS08140
gene id: 67345:CP972_RS08140
uniprot id: A0A5J6HEC5
names: Similarity
messages: Belongs to the peptidase U62 family.

67345:CP972 RS14940
gene id: 67345:CP972_RS14940
uniprot id: A0A5J6H5M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

67345:CP972 RS28055
gene id: 67345:CP972_RS28055
uniprot id: A0A5J6H7C2
names: Similarity
messages: Belongs to the PrpD family.

67345:CP972 RS30555
gene id: 67345:CP972_RS30555
uniprot id: A0A5J6H8P2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS31980
gene id: 67345:CP972_RS31980
uniprot id: A0A5J6HCR6
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

67345:CP972 RS05110
gene id: 67345:CP972_RS05110
uniprot id: A0A5J6GXM2
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

67345:CP972 RS08630
gene id: 67345:CP972_RS08630
uniprot id: A0A5J6GY63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS06380
gene id: 67345:CP972_RS06380
uniprot id: A0A5J6GSS5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

67345:CP972 RS21420
gene id: 67345:CP972_RS21420
uniprot id: A0A5J6H469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

67345:CP972 RS07510
gene id: 67345:CP972_RS07510
uniprot id: A0A5J6HAM6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67345:CP972 RS31570
gene id: 67345:CP972_RS31570
uniprot id: A0A5J6HA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS26695
gene id: 67345:CP972_RS26695
uniprot id: A0A5J6H257
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS18005
gene id: 67345:CP972_RS18005
uniprot id: A0A5J6H3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

67345:CP972 RS11475
gene id: 67345:CP972_RS11475
uniprot id: A0A5J6GZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS12400
gene id: 67345:CP972_RS12400
uniprot id: A0A5J6GWQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

67345:CP972 RS15255
gene id: 67345:CP972_RS15255
uniprot id: A0A5J6H5S4
names: Similarity
messages: Belongs to the peptidase S58 family.

67345:CP972 RS27155
gene id: 67345:CP972_RS27155
uniprot id: A0A5J6HAB4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

67345:CP972 RS09835
gene id: 67345:CP972_RS09835
uniprot id: A0A5J6GVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS16440
gene id: 67345:CP972_RS16440
uniprot id: A0A5J6GXJ2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

67345:CP972 RS02900
gene id: 67345:CP972_RS02900
uniprot id: A0A5J6GV99
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

67345:CP972 RS12010
gene id: 67345:CP972_RS12010
uniprot id: A0A5J6GWJ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

67345:CP972 RS13455
gene id: 67345:CP972_RS13455
uniprot id: A0A5J6H1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS06175
gene id: 67345:CP972_RS06175
uniprot id: A0A5J6GSN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS09155
gene id: 67345:CP972_RS09155
uniprot id: A0A5J6H095
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25460
gene id: 67345:CP972_RS25460
uniprot id: A0A5J6H675
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

67345:CP972 RS26170
gene id: 67345:CP972_RS26170
uniprot id: A0A5J6H1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

67345:CP972 RS22630
gene id: 67345:CP972_RS22630
uniprot id: A0A5J6H5W3
names: Similarity
messages: Belongs to the DSD1 family.

67345:CP972 RS13575
gene id: 67345:CP972_RS13575
uniprot id: A0A5J6H0M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

67345:CP972 RS06355
gene id: 67345:CP972_RS06355
uniprot id: A0A5J6GY87
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS00715
gene id: 67345:CP972_RS00715
uniprot id: A0A5J6GYX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS21415
gene id: 67345:CP972_RS21415
uniprot id: A0A5J6H4J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS25175
gene id: 67345:CP972_RS25175
uniprot id: A0A5J6H404
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

67345:CP972 RS29360
gene id: 67345:CP972_RS29360
uniprot id: A0A5J6H819
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

67345:CP972 RS00150
gene id: 67345:CP972_RS00150
uniprot id: A0A5J6GVX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

67345:CP972 RS21830
gene id: 67345:CP972_RS21830
uniprot id: A0A5J6H771
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS23915
gene id: 67345:CP972_RS23915
uniprot id: A0A5J6H3G4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

67345:CP972 RS11470
gene id: 67345:CP972_RS11470
uniprot id: A0A5J6GVA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

67345:CP972 RS12990
gene id: 67345:CP972_RS12990
uniprot id: A0A5J6GWZ4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

67345:CP972 RS08855
gene id: 67345:CP972_RS08855
uniprot id: A0A5J6H2J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

67345:CP972 RS26145
gene id: 67345:CP972_RS26145
uniprot id: A0A5J6H7M8
names: Similarity
messages: Belongs to the RelA/SpoT family.

67345:CP972 RS26485
gene id: 67345:CP972_RS26485
uniprot id: A0A5J6H7T0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

67345:CP972 RS21320
gene id: 67345:CP972_RS21320
uniprot id: A0A5J6H2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS32305
gene id: 67345:CP972_RS32305
uniprot id: A0A5J6H584
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS13055
gene id: 67345:CP972_RS13055
uniprot id: A0A5J6GW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

67345:CP972 RS23080
gene id: 67345:CP972_RS23080
uniprot id: A0A5J6H7R3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

67345:CP972 RS22260
gene id: 67345:CP972_RS22260
uniprot id: A0A5J6H953
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08890
gene id: 67345:CP972_RS08890
uniprot id: A0A5J6GY52
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24405
gene id: 67345:CP972_RS24405
uniprot id: A0A5J6H174
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

67345:CP972 RS29580
gene id: 67345:CP972_RS29580
uniprot id: A0A5J6H863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

67345:CP972 RS32850
gene id: 67345:CP972_RS32850
uniprot id: A0A5J6H5H4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS18630
gene id: 67345:CP972_RS18630
uniprot id: A0A5J6GYM4
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

67345:CP972 RS31780
gene id: 67345:CP972_RS31780
uniprot id: A0A5J6H719
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

67345:CP972 RS29230
gene id: 67345:CP972_RS29230
uniprot id: A0A5J6H842
names: Similarity
messages: Belongs to the thioesterase family.

67345:CP972 RS23350
gene id: 67345:CP972_RS23350
uniprot id: A0A5J6H9J7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS31920
gene id: 67345:CP972_RS31920
uniprot id: A0A5J6H523
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

67345:CP972 RS06440
gene id: 67345:CP972_RS06440
uniprot id: A0A5J6HAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

67345:CP972 RS31720
gene id: 67345:CP972_RS31720
uniprot id: A0A5J6H941
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

67345:CP972 RS24565
gene id: 67345:CP972_RS24565
uniprot id: A0A5J6H1A1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

67345:CP972 RS07580
gene id: 67345:CP972_RS07580
uniprot id: A0A5J6GUG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS21935
gene id: 67345:CP972_RS21935
uniprot id: A0A5J6H4S7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

67345:CP972 RS25655
gene id: 67345:CP972_RS25655
uniprot id: A0A5J6H1P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

67345:CP972 RS14610
gene id: 67345:CP972_RS14610
uniprot id: A0A5J6GXP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS28545
gene id: 67345:CP972_RS28545
uniprot id: A0A5J6HC23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

67345:CP972 RS11290
gene id: 67345:CP972_RS11290
uniprot id: A0A5J6GW67
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

67345:CP972 RS13800
gene id: 67345:CP972_RS13800
uniprot id: A0A5J6HB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS30385
gene id: 67345:CP972_RS30385
uniprot id: A0A5J6H8J3
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS18205
gene id: 67345:CP972_RS18205
uniprot id: A0A5J6H2R6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS15105
gene id: 67345:CP972_RS15105
uniprot id: A0A5J6H1A4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06255
gene id: 67345:CP972_RS06255
uniprot id: A0A5J6GY70
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09855
gene id: 67345:CP972_RS09855
uniprot id: A0A5J6GYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

67345:CP972 RS05595
gene id: 67345:CP972_RS05595
uniprot id: A0A5J6GTK6
names: Similarity
messages: Belongs to the IMPACT family.

67345:CP972 RS14360
gene id: 67345:CP972_RS14360
uniprot id: A0A5J6GXK5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

67345:CP972 RS09830
gene id: 67345:CP972_RS09830
uniprot id: A0A5J6H304
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

67345:CP972 RS26575
gene id: 67345:CP972_RS26575
uniprot id: A0A5J6H4N4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS16435
gene id: 67345:CP972_RS16435
uniprot id: A0A5J6GYF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS07820
gene id: 67345:CP972_RS07820
uniprot id: A0A5J6GWB4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67345:CP972 RS02370
gene id: 67345:CP972_RS02370
uniprot id: A0A5J6GS33
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS05215
gene id: 67345:CP972_RS05215
uniprot id: A0A5J6GWR7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

67345:CP972 RS20530
gene id: 67345:CP972_RS20530
uniprot id: A0A5J6H071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS07610
gene id: 67345:CP972_RS07610
uniprot id: A0A5J6GYU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS23815
gene id: 67345:CP972_RS23815
uniprot id: A0A5J6HFG6
names: Similarity
messages: Belongs to the terpene synthase family.

67345:CP972 RS12340
gene id: 67345:CP972_RS12340
uniprot id: A0A5J6H204
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19935
gene id: 67345:CP972_RS19935
uniprot id: A0A5J6H020
names: Similarity
messages: Belongs to the group II decarboxylase family.

67345:CP972 RS20770
gene id: 67345:CP972_RS20770
uniprot id: A0A5J6H6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS07000
gene id: 67345:CP972_RS07000
uniprot id: A0A5J6GYZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

67345:CP972 RS16115
gene id: 67345:CP972_RS16115
uniprot id: A0A5J6HF09
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

67345:CP972 RS15390
gene id: 67345:CP972_RS15390
uniprot id: A0A5J6GY14
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

67345:CP972 RS21975
gene id: 67345:CP972_RS21975
uniprot id: A0A5J6H772
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

67345:CP972 RS07135
gene id: 67345:CP972_RS07135
uniprot id: A0A5J6HEA7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS32200
gene id: 67345:CP972_RS32200
uniprot id: A0A5J6H9A6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19740
gene id: 67345:CP972_RS19740
uniprot id: A0A5J6H5Z6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS22255
gene id: 67345:CP972_RS22255
uniprot id: A0A5J6H5Q6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25720
gene id: 67345:CP972_RS25720
uniprot id: A0A5J6H695
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

67345:CP972 RS11280
gene id: 67345:CP972_RS11280
uniprot id: A0A5J6GWA7
names: Similarity
messages: Belongs to the aldose epimerase family.

67345:CP972 RS27405
gene id: 67345:CP972_RS27405
uniprot id: A0A5J6H2M2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67345:CP972 RS31725
gene id: 67345:CP972_RS31725
uniprot id: A0A5J6HAA8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

67345:CP972 RS25865
gene id: 67345:CP972_RS25865
uniprot id: A0A5J6H2Y7
names: Similarity
messages: Belongs to the EccD/Snm4 family.

67345:CP972 RS19425
gene id: 67345:CP972_RS19425
uniprot id: A0A5J6H5V6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

67345:CP972 RS20980
gene id: 67345:CP972_RS20980
uniprot id: A0A5J6H400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

67345:CP972 RS14855
gene id: 67345:CP972_RS14855
uniprot id: A0A5J6H1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

67345:CP972 RS12215
gene id: 67345:CP972_RS12215
uniprot id: A0A5J6H115
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

67345:CP972 RS09560
gene id: 67345:CP972_RS09560
uniprot id: A0A5J6H0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

67345:CP972 RS28300
gene id: 67345:CP972_RS28300
uniprot id: A0A5J6H8N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS21445
gene id: 67345:CP972_RS21445
uniprot id: A0A5J6H0K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

67345:CP972 RS11710
gene id: 67345:CP972_RS11710
uniprot id: A0A5J6GWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS24355
gene id: 67345:CP972_RS24355
uniprot id: A0A5J6H5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

67345:CP972 RS15040
gene id: 67345:CP972_RS15040
uniprot id: A0A5J6H1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

67345:CP972 RS14425
gene id: 67345:CP972_RS14425
uniprot id: A0A5J6GXL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

67345:CP972 RS32710
gene id: 67345:CP972_RS32710
uniprot id: A0A5J6H9J5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

67345:CP972 RS08340
gene id: 67345:CP972_RS08340
uniprot id: A0A5J6GY24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

67345:CP972 RS26275
gene id: 67345:CP972_RS26275
uniprot id: A0A5J6H9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67345:CP972 RS14640
gene id: 67345:CP972_RS14640
uniprot id: A0A5J6H114
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS04475
gene id: 67345:CP972_RS04475
uniprot id: A0A5J6GUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

67345:CP972 RS01435
gene id: 67345:CP972_RS01435
uniprot id: A0A5J6GW33
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS04730
gene id: 67345:CP972_RS04730
uniprot id: A0A5J6GTF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

67345:CP972 RS15115
gene id: 67345:CP972_RS15115
uniprot id: A0A5J6H190
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

67345:CP972 RS13675
gene id: 67345:CP972_RS13675
uniprot id: A0A5J6H1Y5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

67345:CP972 RS01995
gene id: 67345:CP972_RS01995
uniprot id: A0A5J6GSC0
names: Subunit
messages: Homodimer.

67345:CP972 RS17935
gene id: 67345:CP972_RS17935
uniprot id: A0A5J6H0X4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS27860
gene id: 67345:CP972_RS27860
uniprot id: A0A5J6HAU3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67345:CP972 RS03390
gene id: 67345:CP972_RS03390
uniprot id: A0A5J6GVQ6
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS31320
gene id: 67345:CP972_RS31320
uniprot id: A0A5J6H910
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS28930
gene id: 67345:CP972_RS28930
uniprot id: A0A5J6H4B2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS11195
gene id: 67345:CP972_RS11195
uniprot id: A0A5J6GXY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

67345:CP972 RS08750
gene id: 67345:CP972_RS08750
uniprot id: A0A5J6HAR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS10200
gene id: 67345:CP972_RS10200
uniprot id: A0A5J6GUR3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

67345:CP972 RS10755
gene id: 67345:CP972_RS10755
uniprot id: A0A5J6GXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

67345:CP972 RS08825
gene id: 67345:CP972_RS08825
uniprot id: A0A5J6GU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

67345:CP972 RS28230
gene id: 67345:CP972_RS28230
uniprot id: A0A5J6H7L8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS21615
gene id: 67345:CP972_RS21615
uniprot id: A0A5J6H8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

67345:CP972 RS18985
gene id: 67345:CP972_RS18985
uniprot id: A0A5J6H5N4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19910
gene id: 67345:CP972_RS19910
uniprot id: A0A5J6H4L9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS21335
gene id: 67345:CP972_RS21335
uniprot id: A0A5J6H8I1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

67345:CP972 RS07140
gene id: 67345:CP972_RS07140
uniprot id: A0A5J6GXC8
names: Similarity
messages: Belongs to the glutamine synthetase family.

67345:CP972 RS20600
gene id: 67345:CP972_RS20600
uniprot id: A0A5J6H078
names: Similarity
messages: Belongs to the UbiD family.

67345:CP972 RS08390
gene id: 67345:CP972_RS08390
uniprot id: A0A5J6GY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS31115
gene id: 67345:CP972_RS31115
uniprot id: A0A5J6H5B5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21460
gene id: 67345:CP972_RS21460
uniprot id: A0A5J6GZV1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

67345:CP972 RS11595
gene id: 67345:CP972_RS11595
uniprot id: A0A5J6GY50
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

67345:CP972 RS20330
gene id: 67345:CP972_RS20330
uniprot id: A0A5J6H817
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67345:CP972 RS07330
gene id: 67345:CP972_RS07330
uniprot id: A0A5J6GUL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

67345:CP972 RS08410
gene id: 67345:CP972_RS08410
uniprot id: A0A5J6GZC8
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

67345:CP972 RS23215
gene id: 67345:CP972_RS23215
uniprot id: A0A5J6H342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS04495
gene id: 67345:CP972_RS04495
uniprot id: A0A5J6H0H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

67345:CP972 RS20475
gene id: 67345:CP972_RS20475
uniprot id: A0A5J6H0B5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

67345:CP972 RS23860
gene id: 67345:CP972_RS23860
uniprot id: A0A5J6H5D0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS31825
gene id: 67345:CP972_RS31825
uniprot id: A0A5J6H984
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS07260
gene id: 67345:CP972_RS07260
uniprot id: A0A5J6GXK6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

67345:CP972 RS25495
gene id: 67345:CP972_RS25495
uniprot id: A0A5J6H1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS16305
gene id: 67345:CP972_RS16305
uniprot id: A0A5J6H4A1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

67345:CP972 RS13965
gene id: 67345:CP972_RS13965
uniprot id: A0A5J6H0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS11205
gene id: 67345:CP972_RS11205
uniprot id: A0A5J6H0L7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

67345:CP972 RS20975
gene id: 67345:CP972_RS20975
uniprot id: A0A5J6H458
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21530
gene id: 67345:CP972_RS21530
uniprot id: A0A5J6H488
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS25355
gene id: 67345:CP972_RS25355
uniprot id: A0A5J6HAP6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

67345:CP972 RS30700
gene id: 67345:CP972_RS30700
uniprot id: A0A5J6H4J6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS23075
gene id: 67345:CP972_RS23075
uniprot id: A0A5J6H182
names: Caution
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS23445
gene id: 67345:CP972_RS23445
uniprot id: A0A5J6H6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67345:CP972 RS22290
gene id: 67345:CP972_RS22290
uniprot id: A0A5J6H4K9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

67345:CP972 RS25410
gene id: 67345:CP972_RS25410
uniprot id: A0A5J6HAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

67345:CP972 RS20180
gene id: 67345:CP972_RS20180
uniprot id: A0A5J6H3M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

67345:CP972 RS24175
gene id: 67345:CP972_RS24175
uniprot id: A0A5J6H5H1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

67345:CP972 RS27640
gene id: 67345:CP972_RS27640
uniprot id: A0A5J6H8D2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS06210
gene id: 67345:CP972_RS06210
uniprot id: A0A5J6GU76
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

67345:CP972 RS29325
gene id: 67345:CP972_RS29325
uniprot id: A0A5J6H3Z6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

67345:CP972 RS21740
gene id: 67345:CP972_RS21740
uniprot id: A0A5J6H4C2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

67345:CP972 RS00145
gene id: 67345:CP972_RS00145
uniprot id: A0A5J6GRR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS20955
gene id: 67345:CP972_RS20955
uniprot id: A0A5J6H6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

67345:CP972 RS06345
gene id: 67345:CP972_RS06345
uniprot id: A0A5J6GVI8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

67345:CP972 RS16235
gene id: 67345:CP972_RS16235
uniprot id: A0A5J6H654
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

67345:CP972 RS25605
gene id: 67345:CP972_RS25605
uniprot id: A0A5J6H6C7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS16255
gene id: 67345:CP972_RS16255
uniprot id: A0A5J6GXG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

67345:CP972 RS10215
gene id: 67345:CP972_RS10215
uniprot id: A0A5J6GYS3
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS03570
gene id: 67345:CP972_RS03570
uniprot id: A0A5J6GSL9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS05970
gene id: 67345:CP972_RS05970
uniprot id: A0A5J6GU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

67345:CP972 RS20755
gene id: 67345:CP972_RS20755
uniprot id: A0A5J6H505
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS27870
gene id: 67345:CP972_RS27870
uniprot id: A0A5J6H2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS27375
gene id: 67345:CP972_RS27375
uniprot id: A0A5J6H896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS18075
gene id: 67345:CP972_RS18075
uniprot id: A0A5J6H583
names: Similarity
messages: Belongs to the thioredoxin family.

67345:CP972 RS21375
gene id: 67345:CP972_RS21375
uniprot id: A0A5J6H463
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

67345:CP972 RS29220
gene id: 67345:CP972_RS29220
uniprot id: A0A5J6H3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

67345:CP972 RS30920
gene id: 67345:CP972_RS30920
uniprot id: A0A5J6H6M0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS12545
gene id: 67345:CP972_RS12545
uniprot id: A0A5J6H039
names: Similarity
messages: Belongs to the peptidase M1 family.

67345:CP972 RS14205
gene id: 67345:CP972_RS14205
uniprot id: A0A5J6H0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

67345:CP972 RS20775
gene id: 67345:CP972_RS20775
uniprot id: A0A5J6H0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS11035
gene id: 67345:CP972_RS11035
uniprot id: A0A5J6GW76
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08780
gene id: 67345:CP972_RS08780
uniprot id: A0A5J6GYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

67345:CP972 RS22920
gene id: 67345:CP972_RS22920
uniprot id: A0A5J6H301
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS11960
gene id: 67345:CP972_RS11960
uniprot id: A0A5J6GZV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

67345:CP972 RS11000
gene id: 67345:CP972_RS11000
uniprot id: A0A5J6GZA7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

67345:CP972 RS29275
gene id: 67345:CP972_RS29275
uniprot id: A0A5J6H4G8
names: Similarity
messages: Belongs to the thioesterase family.

67345:CP972 RS22065
gene id: 67345:CP972_RS22065
uniprot id: A0A5J6H4H7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19195
gene id: 67345:CP972_RS19195
uniprot id: A0A5J6H5R8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS11980
gene id: 67345:CP972_RS11980
uniprot id: A0A5J6GZU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

67345:CP972 RS13215
gene id: 67345:CP972_RS13215
uniprot id: A0A5J6GX45
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

67345:CP972 RS03395
gene id: 67345:CP972_RS03395
uniprot id: A0A5J6GWV6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS15290
gene id: 67345:CP972_RS15290
uniprot id: A0A5J6GZQ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

67345:CP972 RS01150
gene id: 67345:CP972_RS01150
uniprot id: A0A5J6GV29
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67345:CP972 RS31535
gene id: 67345:CP972_RS31535
uniprot id: A0A5J6H4X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

67345:CP972 RS12795
gene id: 67345:CP972_RS12795
uniprot id: A0A5J6H4E3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

67345:CP972 RS00750
gene id: 67345:CP972_RS00750
uniprot id: A0A5J6GRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

67345:CP972 RS05090
gene id: 67345:CP972_RS05090
uniprot id: A0A5J6GWP7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS00540
gene id: 67345:CP972_RS00540
uniprot id: A0A5J6GVU0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS25230
gene id: 67345:CP972_RS25230
uniprot id: A0A5J6H413
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

67345:CP972 RS13830
gene id: 67345:CP972_RS13830
uniprot id: A0A5J6H2W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

67345:CP972 RS24480
gene id: 67345:CP972_RS24480
uniprot id: A0A5J6H5N6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

67345:CP972 RS14270
gene id: 67345:CP972_RS14270
uniprot id: A0A5J6H0V5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

67345:CP972 RS02235
gene id: 67345:CP972_RS02235
uniprot id: A0A5J6GVF5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS05340
gene id: 67345:CP972_RS05340
uniprot id: A0A5J6GWL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS10670
gene id: 67345:CP972_RS10670
uniprot id: A0A5J6HB71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS03195
gene id: 67345:CP972_RS03195
uniprot id: A0A5J6GTP7
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

67345:CP972 RS21180
gene id: 67345:CP972_RS21180
uniprot id: A0A5J6H6R7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25190
gene id: 67345:CP972_RS25190
uniprot id: A0A5J6HAM1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

67345:CP972 RS05500
gene id: 67345:CP972_RS05500
uniprot id: A0A5J6GWP6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

67345:CP972 RS31130
gene id: 67345:CP972_RS31130
uniprot id: A0A5J6H8Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

67345:CP972 RS11225
gene id: 67345:CP972_RS11225
uniprot id: A0A5J6H1C3
names: Similarity
messages: Belongs to the aldose epimerase family.

67345:CP972 RS05625
gene id: 67345:CP972_RS05625
uniprot id: A0A5J6GWR9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

67345:CP972 RS04870
gene id: 67345:CP972_RS04870
uniprot id: A0A5J6GW86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

67345:CP972 RS17595
gene id: 67345:CP972_RS17595
uniprot id: A0A5J6H2G7
names: Similarity
messages: Belongs to the pirin family.

67345:CP972 RS33010
gene id: 67345:CP972_RS33010
uniprot id: A0A5J6HE18
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS08815
gene id: 67345:CP972_RS08815
uniprot id: A0A5J6H028
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

67345:CP972 RS20020
gene id: 67345:CP972_RS20020
uniprot id: A0A5J6H3K3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

67345:CP972 RS30420
gene id: 67345:CP972_RS30420
uniprot id: A0A5J6H503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

67345:CP972 RS01550
gene id: 67345:CP972_RS01550
uniprot id: A0A5J6GUU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

67345:CP972 RS06615
gene id: 67345:CP972_RS06615
uniprot id: A0A5J6GVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS33115
gene id: 67345:CP972_RS33115
uniprot id: A0A5J6H7P0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS23455
gene id: 67345:CP972_RS23455
uniprot id: A0A5J6H1E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

67345:CP972 RS29430
gene id: 67345:CP972_RS29430
uniprot id: A0A5J6H5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS06225
gene id: 67345:CP972_RS06225
uniprot id: A0A5J6GSP7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

67345:CP972 RS06540
gene id: 67345:CP972_RS06540
uniprot id: A0A5J6GU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

67345:CP972 RS21715
gene id: 67345:CP972_RS21715
uniprot id: A0A5J6GZY2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS10095
gene id: 67345:CP972_RS10095
uniprot id: A0A5J6HAL7
names: Similarity
messages: Belongs to the glutamine synthetase family.

67345:CP972 RS24695
gene id: 67345:CP972_RS24695
uniprot id: A0A5J6H2E0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

67345:CP972 RS05330
gene id: 67345:CP972_RS05330
uniprot id: A0A5J6GWH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

67345:CP972 RS04490
gene id: 67345:CP972_RS04490
uniprot id: A0A5J6GXB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

67345:CP972 RS05050
gene id: 67345:CP972_RS05050
uniprot id: A0A5J6H7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

67345:CP972 RS19865
gene id: 67345:CP972_RS19865
uniprot id: A0A5J6H010
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

67345:CP972 RS26130
gene id: 67345:CP972_RS26130
uniprot id: A0A5J6H6G1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67345:CP972 RS25345
gene id: 67345:CP972_RS25345
uniprot id: A0A5J6H661
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS21725
gene id: 67345:CP972_RS21725
uniprot id: A0A5J6H4B8
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

67345:CP972 RS32485
gene id: 67345:CP972_RS32485
uniprot id: A0A5J6HCY7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS18690
gene id: 67345:CP972_RS18690
uniprot id: A0A5J6H354
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

67345:CP972 RS16295
gene id: 67345:CP972_RS16295
uniprot id: A0A5J6H662
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

67345:CP972 RS08565
gene id: 67345:CP972_RS08565
uniprot id: A0A5J6GY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS08195
gene id: 67345:CP972_RS08195
uniprot id: A0A5J6GXU5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS17405
gene id: 67345:CP972_RS17405
uniprot id: A0A5J6GYW4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS03055
gene id: 67345:CP972_RS03055
uniprot id: A0A5J6GVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS10260
gene id: 67345:CP972_RS10260
uniprot id: A0A5J6H370
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS15830
gene id: 67345:CP972_RS15830
uniprot id: A0A5J6H2T1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

67345:CP972 RS00720
gene id: 67345:CP972_RS00720
uniprot id: A0A5J6GRZ1
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

67345:CP972 RS28220
gene id: 67345:CP972_RS28220
uniprot id: A0A5J6H3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS05660
gene id: 67345:CP972_RS05660
uniprot id: A0A5J6GTL6
names: Similarity
messages: Belongs to the XFP family.

67345:CP972 RS05530
gene id: 67345:CP972_RS05530
uniprot id: A0A5J6GY92
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS25580
gene id: 67345:CP972_RS25580
uniprot id: A0A5J6HAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS18975
gene id: 67345:CP972_RS18975
uniprot id: A0A5J6GZK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS25400
gene id: 67345:CP972_RS25400
uniprot id: A0A5J6H7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

67345:CP972 RS31790
gene id: 67345:CP972_RS31790
uniprot id: A0A5J6HAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

67345:CP972 RS15495
gene id: 67345:CP972_RS15495
uniprot id: A0A5J6H801
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS32090
gene id: 67345:CP972_RS32090
uniprot id: A0A5J6HDL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

67345:CP972 RS25695
gene id: 67345:CP972_RS25695
uniprot id: A0A5J6H2F6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS15030
gene id: 67345:CP972_RS15030
uniprot id: A0A5J6GXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

67345:CP972 RS13860
gene id: 67345:CP972_RS13860
uniprot id: A0A5J6GZ41
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS23480
gene id: 67345:CP972_RS23480
uniprot id: A0A5J6H552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

67345:CP972 RS02755
gene id: 67345:CP972_RS02755
uniprot id: A0A5J6GVM6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS04605
gene id: 67345:CP972_RS04605
uniprot id: A0A5J6GXR8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS11345
gene id: 67345:CP972_RS11345
uniprot id: A0A5J6GWB5
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

67345:CP972 RS21455
gene id: 67345:CP972_RS21455
uniprot id: A0A5J6H0U7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

67345:CP972 RS13415
gene id: 67345:CP972_RS13415
uniprot id: A0A5J6HAU5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67345:CP972 RS19985
gene id: 67345:CP972_RS19985
uniprot id: A0A5J6GZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

67345:CP972 RS25850
gene id: 67345:CP972_RS25850
uniprot id: A0A5J6H2I0
names: Similarity
messages: Belongs to the WXG100 family.

67345:CP972 RS31785
gene id: 67345:CP972_RS31785
uniprot id: A0A5J6H950
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS30795
gene id: 67345:CP972_RS30795
uniprot id: A0A5J6H8Q1
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

67345:CP972 RS26355
gene id: 67345:CP972_RS26355
uniprot id: A0A5J6H4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS14675
gene id: 67345:CP972_RS14675
uniprot id: A0A5J6GXQ2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

67345:CP972 RS25055
gene id: 67345:CP972_RS25055
uniprot id: A0A5J6H281
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

67345:CP972 RS14615
gene id: 67345:CP972_RS14615
uniprot id: A0A5J6GWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

67345:CP972 RS22520
gene id: 67345:CP972_RS22520
uniprot id: A0A5J6H5U3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67345:CP972 RS13265
gene id: 67345:CP972_RS13265
uniprot id: A0A5J6H4N6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS01870
gene id: 67345:CP972_RS01870
uniprot id: A0A5J6GSA3
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19340
gene id: 67345:CP972_RS19340
uniprot id: A0A5J6H1H6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS29610
gene id: 67345:CP972_RS29610
uniprot id: A0A5J6H4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67345:CP972 RS20340
gene id: 67345:CP972_RS20340
uniprot id: A0A5J6H044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

67345:CP972 RS18180
gene id: 67345:CP972_RS18180
uniprot id: A0A5J6GZ91
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25470
gene id: 67345:CP972_RS25470
uniprot id: A0A5J6HAR9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24820
gene id: 67345:CP972_RS24820
uniprot id: A0A5J6H3U8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

67345:CP972 RS17455
gene id: 67345:CP972_RS17455
uniprot id: A0A5J6GYX0
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS27370
gene id: 67345:CP972_RS27370
uniprot id: A0A5J6H7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS30980
gene id: 67345:CP972_RS30980
uniprot id: A0A5J6H8T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

67345:CP972 RS03005
gene id: 67345:CP972_RS03005
uniprot id: A0A5J6GVN7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS05460
gene id: 67345:CP972_RS05460
uniprot id: A0A5J6GY78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS15155
gene id: 67345:CP972_RS15155
uniprot id: A0A5J6GXX7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

67345:CP972 RS27845
gene id: 67345:CP972_RS27845
uniprot id: A0A5J6H8F5
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24420
gene id: 67345:CP972_RS24420
uniprot id: A0A5J6H3N9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS07990
gene id: 67345:CP972_RS07990
uniprot id: A0A5J6GZF4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21675
gene id: 67345:CP972_RS21675
uniprot id: A0A5J6H2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67345:CP972 RS25635
gene id: 67345:CP972_RS25635
uniprot id: A0A5J6H2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS28695
gene id: 67345:CP972_RS28695
uniprot id: A0A5J6H3E6
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

67345:CP972 RS13250
gene id: 67345:CP972_RS13250
uniprot id: A0A5J6GYW2
names: Similarity
messages: Belongs to the IucA/IucC family.

67345:CP972 RS20735
gene id: 67345:CP972_RS20735
uniprot id: A0A5J6H419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS18260
gene id: 67345:CP972_RS18260
uniprot id: A0A5J6H2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67345:CP972 RS06315
gene id: 67345:CP972_RS06315
uniprot id: A0A5J6GU92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

67345:CP972 RS03625
gene id: 67345:CP972_RS03625
uniprot id: A0A5J6GXC4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

67345:CP972 RS00295
gene id: 67345:CP972_RS00295
uniprot id: A0A5J6GVM3
names: Similarity
messages: Belongs to the PrpF family.

67345:CP972 RS23765
gene id: 67345:CP972_RS23765
uniprot id: A0A5J6H835
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67345:CP972 RS22120
gene id: 67345:CP972_RS22120
uniprot id: A0A5J6H763
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS29455
gene id: 67345:CP972_RS29455
uniprot id: A0A5J6HCG9
names: Similarity
messages: Belongs to the DapA family.

67345:CP972 RS09825
gene id: 67345:CP972_RS09825
uniprot id: A0A5J6H001
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

67345:CP972 RS33240
gene id: 67345:CP972_RS33240
uniprot id: A0A5J6HDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS13270
gene id: 67345:CP972_RS13270
uniprot id: A0A5J6GX58
names: Similarity
messages: Belongs to the universal stress protein A family.

67345:CP972 RS21545
gene id: 67345:CP972_RS21545
uniprot id: A0A5J6H8M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24335
gene id: 67345:CP972_RS24335
uniprot id: A0A5J6H1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

67345:CP972 RS18030
gene id: 67345:CP972_RS18030
uniprot id: A0A5J6GZ71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

67345:CP972 RS24910
gene id: 67345:CP972_RS24910
uniprot id: A0A5J6H8J1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

67345:CP972 RS27400
gene id: 67345:CP972_RS27400
uniprot id: A0A5J6H3K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS32080
gene id: 67345:CP972_RS32080
uniprot id: A0A5J6H991
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS06200
gene id: 67345:CP972_RS06200
uniprot id: A0A5J6GY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

67345:CP972 RS08895
gene id: 67345:CP972_RS08895
uniprot id: A0A5J6GWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

67345:CP972 RS02190
gene id: 67345:CP972_RS02190
uniprot id: A0A5J6GV08
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24025
gene id: 67345:CP972_RS24025
uniprot id: A0A5J6H889
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

67345:CP972 RS21225
gene id: 67345:CP972_RS21225
uniprot id: A0A5J6H8F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

67345:CP972 RS07235
gene id: 67345:CP972_RS07235
uniprot id: A0A5J6GUB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67345:CP972 RS07740
gene id: 67345:CP972_RS07740
uniprot id: A0A5J6GUS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS20450
gene id: 67345:CP972_RS20450
uniprot id: A0A5J6H3R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS08660
gene id: 67345:CP972_RS08660
uniprot id: A0A5J6GU22
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

67345:CP972 RS18235
gene id: 67345:CP972_RS18235
uniprot id: A0A5J6H5C0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

67345:CP972 RS22735
gene id: 67345:CP972_RS22735
uniprot id: A0A5J6H2X3
names: Similarity
messages: Belongs to the GSP E family.

67345:CP972 RS19240
gene id: 67345:CP972_RS19240
uniprot id: A0A5J6GZP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS21910
gene id: 67345:CP972_RS21910
uniprot id: A0A5J6H8T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

67345:CP972 RS06870
gene id: 67345:CP972_RS06870
uniprot id: A0A5J6GT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

67345:CP972 RS18000
gene id: 67345:CP972_RS18000
uniprot id: A0A5J6H2P0
names: Similarity
messages: Belongs to the UPF0232 family.

67345:CP972 RS07750
gene id: 67345:CP972_RS07750
uniprot id: A0A5J6GUI4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

67345:CP972 RS30310
gene id: 67345:CP972_RS30310
uniprot id: A0A5J6H8K6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS32555
gene id: 67345:CP972_RS32555
uniprot id: A0A5J6H9H4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS19430
gene id: 67345:CP972_RS19430
uniprot id: A0A5J6GZU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS14260
gene id: 67345:CP972_RS14260
uniprot id: A0A5J6GWK4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

67345:CP972 RS23755
gene id: 67345:CP972_RS23755
uniprot id: A0A5J6H9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS12210
gene id: 67345:CP972_RS12210
uniprot id: A0A5J6GZY6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67345:CP972 RS06510
gene id: 67345:CP972_RS06510
uniprot id: A0A5J6GX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

67345:CP972 RS25375
gene id: 67345:CP972_RS25375
uniprot id: A0A5J6H1K4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

67345:CP972 RS25440
gene id: 67345:CP972_RS25440
uniprot id: A0A5J6HG08
names: Similarity
messages: Belongs to the DprA/Smf family.

67345:CP972 RS05210
gene id: 67345:CP972_RS05210
uniprot id: A0A5J6GS56
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS31775
gene id: 67345:CP972_RS31775
uniprot id: A0A5J6H981
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

67345:CP972 RS32695
gene id: 67345:CP972_RS32695
uniprot id: A0A5J6HD25
names: Similarity
messages: Belongs to the terpene synthase family.

67345:CP972 RS03755
gene id: 67345:CP972_RS03755
uniprot id: A0A5J6GT19
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67345:CP972 RS18185
gene id: 67345:CP972_RS18185
uniprot id: A0A5J6H5A5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

67345:CP972 RS08155
gene id: 67345:CP972_RS08155
uniprot id: A0A5J6GZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67345:CP972 RS18850
gene id: 67345:CP972_RS18850
uniprot id: A0A5J6H5L5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

67345:CP972 RS06045
gene id: 67345:CP972_RS06045
uniprot id: A0A5J6GYH3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS32340
gene id: 67345:CP972_RS32340
uniprot id: A0A5J6HDQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS17310
gene id: 67345:CP972_RS17310
uniprot id: A0A5J6GYV0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

67345:CP972 RS22345
gene id: 67345:CP972_RS22345
uniprot id: A0A5J6H4Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS13430
gene id: 67345:CP972_RS13430
uniprot id: A0A5J6GW89
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67345:CP972 RS21265
gene id: 67345:CP972_RS21265
uniprot id: A0A5J6H297
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

67345:CP972 RS10425
gene id: 67345:CP972_RS10425
uniprot id: A0A5J6GYV5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

67345:CP972 RS02200
gene id: 67345:CP972_RS02200
uniprot id: A0A5J6GUY3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

67345:CP972 RS09990
gene id: 67345:CP972_RS09990
uniprot id: A0A5J6GYY7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

67345:CP972 RS22235
gene id: 67345:CP972_RS22235
uniprot id: A0A5J6H4X1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

67345:CP972 RS09220
gene id: 67345:CP972_RS09220
uniprot id: A0A5J6H0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

67345:CP972 RS16075
gene id: 67345:CP972_RS16075
uniprot id: A0A5J6H1K8
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS09060
gene id: 67345:CP972_RS09060
uniprot id: A0A5J6GY73
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS21625
gene id: 67345:CP972_RS21625
uniprot id: A0A5J6H705
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

67345:CP972 RS26065
gene id: 67345:CP972_RS26065
uniprot id: A0A5J6H1V6
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

67345:CP972 RS31375
gene id: 67345:CP972_RS31375
uniprot id: A0A5J6H921
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS24935
gene id: 67345:CP972_RS24935
uniprot id: A0A5J6H3W6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

67345:CP972 RS11835
gene id: 67345:CP972_RS11835
uniprot id: A0A5J6GZQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

67345:CP972 RS04405
gene id: 67345:CP972_RS04405
uniprot id: A0A5J6GSZ6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

67345:CP972 RS02240
gene id: 67345:CP972_RS02240
uniprot id: A0A5J6H611
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS29590
gene id: 67345:CP972_RS29590
uniprot id: A0A5J6H9W7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

67345:CP972 RS04940
gene id: 67345:CP972_RS04940
uniprot id: A0A5J6H0Q4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS01325
gene id: 67345:CP972_RS01325
uniprot id: A0A5J6H737
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS31040
gene id: 67345:CP972_RS31040
uniprot id: A0A5J6HA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS25480
gene id: 67345:CP972_RS25480
uniprot id: A0A5J6H2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

67345:CP972 RS22720
gene id: 67345:CP972_RS22720
uniprot id: A0A5J6H546
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24285
gene id: 67345:CP972_RS24285
uniprot id: A0A5J6H8D4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS17360
gene id: 67345:CP972_RS17360
uniprot id: A0A5J6H0N1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

67345:CP972 RS14805
gene id: 67345:CP972_RS14805
uniprot id: A0A5J6HB36
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

67345:CP972 RS16335
gene id: 67345:CP972_RS16335
uniprot id: A0A5J6H064
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

67345:CP972 RS23150
gene id: 67345:CP972_RS23150
uniprot id: A0A5J6H0L6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

67345:CP972 RS14915
gene id: 67345:CP972_RS14915
uniprot id: A0A5J6H164
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS14080
gene id: 67345:CP972_RS14080
uniprot id: A0A5J6H0U0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

67345:CP972 RS15295
gene id: 67345:CP972_RS15295
uniprot id: A0A5J6HBH3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

67345:CP972 RS18490
gene id: 67345:CP972_RS18490
uniprot id: A0A5J6GYK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS26420
gene id: 67345:CP972_RS26420
uniprot id: A0A5J6HB53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67345:CP972 RS07360
gene id: 67345:CP972_RS07360
uniprot id: A0A5J6GW38
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

67345:CP972 RS13050
gene id: 67345:CP972_RS13050
uniprot id: A0A5J6GX03
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

67345:CP972 RS07320
gene id: 67345:CP972_RS07320
uniprot id: A0A5J6GYN9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

67345:CP972 RS30530
gene id: 67345:CP972_RS30530
uniprot id: A0A5J6H4H5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS12300
gene id: 67345:CP972_RS12300
uniprot id: A0A5J6H047
names: Similarity
messages: Belongs to the catalase family.

67345:CP972 RS18160
gene id: 67345:CP972_RS18160
uniprot id: A0A5J6H118
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

67345:CP972 RS13315
gene id: 67345:CP972_RS13315
uniprot id: A0A5J6H0F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

67345:CP972 RS09535
gene id: 67345:CP972_RS09535
uniprot id: A0A5J6GYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

67345:CP972 RS10635
gene id: 67345:CP972_RS10635
uniprot id: A0A5J6GYY3
names: Similarity
messages: Belongs to the UPF0246 family.

67345:CP972 RS31225
gene id: 67345:CP972_RS31225
uniprot id: A0A5J6H4S6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67345:CP972 RS24350
gene id: 67345:CP972_RS24350
uniprot id: A0A5J6H166
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

67345:CP972 RS25880
gene id: 67345:CP972_RS25880
uniprot id: A0A5J6H6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

67345:CP972 RS32755
gene id: 67345:CP972_RS32755
uniprot id: A0A5J6H6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

67345:CP972 RS23500
gene id: 67345:CP972_RS23500
uniprot id: A0A5J6H9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS12385
gene id: 67345:CP972_RS12385
uniprot id: A0A5J6H481
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

67345:CP972 RS13505
gene id: 67345:CP972_RS13505
uniprot id: A0A5J6H0L3
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

67345:CP972 RS14560
gene id: 67345:CP972_RS14560
uniprot id: A0A5J6GWQ5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

67345:CP972 RS04510
gene id: 67345:CP972_RS04510
uniprot id: A0A5J6GXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS08935
gene id: 67345:CP972_RS08935
uniprot id: A0A5J6GYI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

67345:CP972 RS31630
gene id: 67345:CP972_RS31630
uniprot id: A0A5J6H4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS23870
gene id: 67345:CP972_RS23870
uniprot id: A0A5J6H9U6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS26435
gene id: 67345:CP972_RS26435
uniprot id: A0A5J6H8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS02930
gene id: 67345:CP972_RS02930
uniprot id: A0A5J6GWZ8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS33420
gene id: 67345:CP972_RS33420
uniprot id: A0A5J6H9W4
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS04555
gene id: 67345:CP972_RS04555
uniprot id: A0A5J6GTC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67345:CP972 RS26725
gene id: 67345:CP972_RS26725
uniprot id: A0A5J6H4Q2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

67345:CP972 RS10680
gene id: 67345:CP972_RS10680
uniprot id: A0A5J6GVV2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS05475
gene id: 67345:CP972_RS05475
uniprot id: A0A5J6GSA4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS20215
gene id: 67345:CP972_RS20215
uniprot id: A0A5J6H070
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS18125
gene id: 67345:CP972_RS18125
uniprot id: A0A5J6GZ74
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

67345:CP972 RS33320
gene id: 67345:CP972_RS33320
uniprot id: A0A5J6H9Z8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

67345:CP972 RS19535
gene id: 67345:CP972_RS19535
uniprot id: A0A5J6H5X2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

67345:CP972 RS07370
gene id: 67345:CP972_RS07370
uniprot id: A0A5J6GYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

67345:CP972 RS08885
gene id: 67345:CP972_RS08885
uniprot id: A0A5J6GYH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

67345:CP972 RS14810
gene id: 67345:CP972_RS14810
uniprot id: A0A5J6H146
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

67345:CP972 RS24430
gene id: 67345:CP972_RS24430
uniprot id: A0A5J6H6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

67345:CP972 RS30320
gene id: 67345:CP972_RS30320
uniprot id: A0A5J6H8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

67345:CP972 RS08295
gene id: 67345:CP972_RS08295
uniprot id: A0A5J6GV55
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS21930
gene id: 67345:CP972_RS21930
uniprot id: A0A5J6H016
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

67345:CP972 RS22245
gene id: 67345:CP972_RS22245
uniprot id: A0A5J6H2P2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

67345:CP972 RS14620
gene id: 67345:CP972_RS14620
uniprot id: A0A5J6H185
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS11365
gene id: 67345:CP972_RS11365
uniprot id: A0A5J6GZK8
names: Similarity
messages: Belongs to the asp23 family.

67345:CP972 RS06920
gene id: 67345:CP972_RS06920
uniprot id: A0A5J6GUF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

67345:CP972 RS29085
gene id: 67345:CP972_RS29085
uniprot id: A0A5J6H3V6
names: Similarity
messages: Belongs to the malate synthase family.

67345:CP972 RS15750
gene id: 67345:CP972_RS15750
uniprot id: A0A5J6H1J7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67345:CP972 RS00775
gene id: 67345:CP972_RS00775
uniprot id: A0A5J6H5Y4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS02405
gene id: 67345:CP972_RS02405
uniprot id: A0A5J6GZI4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS09500
gene id: 67345:CP972_RS09500
uniprot id: A0A5J6GVN0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

67345:CP972 RS10270
gene id: 67345:CP972_RS10270
uniprot id: A0A5J6H0V0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS27130
gene id: 67345:CP972_RS27130
uniprot id: A0A5J6H4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

67345:CP972 RS13905
gene id: 67345:CP972_RS13905
uniprot id: A0A5J6H0P8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

67345:CP972 RS09850
gene id: 67345:CP972_RS09850
uniprot id: A0A5J6GUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

67345:CP972 RS06245
gene id: 67345:CP972_RS06245
uniprot id: A0A5J6GX47
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS14225
gene id: 67345:CP972_RS14225
uniprot id: A0A5J6H5B3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

67345:CP972 RS09465
gene id: 67345:CP972_RS09465
uniprot id: A0A5J6GYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

67345:CP972 RS27895
gene id: 67345:CP972_RS27895
uniprot id: A0A5J6H8G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS15740
gene id: 67345:CP972_RS15740
uniprot id: A0A5J6GX78
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

67345:CP972 RS20630
gene id: 67345:CP972_RS20630
uniprot id: A0A5J6H3U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

67345:CP972 RS09395
gene id: 67345:CP972_RS09395
uniprot id: A0A5J6GUD8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS07500
gene id: 67345:CP972_RS07500
uniprot id: A0A5J6GUP2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS30850
gene id: 67345:CP972_RS30850
uniprot id: A0A5J6H6L2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

67345:CP972 RS21405
gene id: 67345:CP972_RS21405
uniprot id: A0A5J6H0T9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

67345:CP972 RS29800
gene id: 67345:CP972_RS29800
uniprot id: A0A5J6H8A3
names: Similarity
messages: Belongs to the peptidase C56 family.

67345:CP972 RS07270
gene id: 67345:CP972_RS07270
uniprot id: A0A5J6H1V5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

67345:CP972 RS17880
gene id: 67345:CP972_RS17880
uniprot id: A0A5J6H2L8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS03535
gene id: 67345:CP972_RS03535
uniprot id: A0A5J6GTV7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

67345:CP972 RS31565
gene id: 67345:CP972_RS31565
uniprot id: A0A5J6H914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS22020
gene id: 67345:CP972_RS22020
uniprot id: A0A5J6H5L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS19110
gene id: 67345:CP972_RS19110
uniprot id: A0A5J6H361
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

67345:CP972 RS08350
gene id: 67345:CP972_RS08350
uniprot id: A0A5J6H2C5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

67345:CP972 RS10150
gene id: 67345:CP972_RS10150
uniprot id: A0A5J6GYR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67345:CP972 RS25665
gene id: 67345:CP972_RS25665
uniprot id: A0A5J6H7E2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67345:CP972 RS05830
gene id: 67345:CP972_RS05830
uniprot id: A0A5J6H8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS10290
gene id: 67345:CP972_RS10290
uniprot id: A0A5J6GZ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

67345:CP972 RS21330
gene id: 67345:CP972_RS21330
uniprot id: A0A5J6H596
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

67345:CP972 RS30160
gene id: 67345:CP972_RS30160
uniprot id: A0A5J6H4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS27570
gene id: 67345:CP972_RS27570
uniprot id: A0A5J6H8C1
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

67345:CP972 RS26825
gene id: 67345:CP972_RS26825
uniprot id: A0A5J6H3C8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

67345:CP972 RS31800
gene id: 67345:CP972_RS31800
uniprot id: A0A5J6H502
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

67345:CP972 RS11520
gene id: 67345:CP972_RS11520
uniprot id: A0A5J6H1M4
names: Similarity
messages: Belongs to the CdaR family.

67345:CP972 RS31205
gene id: 67345:CP972_RS31205
uniprot id: A0A5J6HCW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS25360
gene id: 67345:CP972_RS25360
uniprot id: A0A5J6H2B9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

67345:CP972 RS06220
gene id: 67345:CP972_RS06220
uniprot id: A0A5J6GTW7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

67345:CP972 RS32600
gene id: 67345:CP972_RS32600
uniprot id: A0A5J6H5C9
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS22925
gene id: 67345:CP972_RS22925
uniprot id: A0A5J6H4W1
names: Similarity
messages: Belongs to the FBPase class 2 family.

67345:CP972 RS06050
gene id: 67345:CP972_RS06050
uniprot id: A0A5J6GTT7
names: Similarity
messages: Belongs to the oxoprolinase family.

67345:CP972 RS10040
gene id: 67345:CP972_RS10040
uniprot id: A0A5J6GYP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

67345:CP972 RS07070
gene id: 67345:CP972_RS07070
uniprot id: A0A5J6GXB7
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS20355
gene id: 67345:CP972_RS20355
uniprot id: A0A5J6GZD6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS08465
gene id: 67345:CP972_RS08465
uniprot id: A0A5J6GZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

67345:CP972 RS24745
gene id: 67345:CP972_RS24745
uniprot id: A0A5J6H2E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS21255
gene id: 67345:CP972_RS21255
uniprot id: A0A5J6H497
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

67345:CP972 RS28390
gene id: 67345:CP972_RS28390
uniprot id: A0A5J6H7I6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

67345:CP972 RS15590
gene id: 67345:CP972_RS15590
uniprot id: A0A5J6H1F0
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS33270
gene id: 67345:CP972_RS33270
uniprot id: A0A5J6H9Y7
names: Similarity
messages: Belongs to the HupF/HypC family.

67345:CP972 RS16260
gene id: 67345:CP972_RS16260
uniprot id: A0A5J6H225
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS23810
gene id: 67345:CP972_RS23810
uniprot id: A0A5J6H9T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

67345:CP972 RS03095
gene id: 67345:CP972_RS03095
uniprot id: A0A5J6GST3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS25550
gene id: 67345:CP972_RS25550
uniprot id: A0A5J6H6B4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

67345:CP972 RS22320
gene id: 67345:CP972_RS22320
uniprot id: A0A5J6H0X8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08285
gene id: 67345:CP972_RS08285
uniprot id: A0A5J6GZA9
names: Similarity
messages: Belongs to the asp23 family.

67345:CP972 RS33425
gene id: 67345:CP972_RS33425
uniprot id: A0A5J6H9X6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS27930
gene id: 67345:CP972_RS27930
uniprot id: A0A5J6H3C5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

67345:CP972 RS28200
gene id: 67345:CP972_RS28200
uniprot id: A0A5J6HBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

67345:CP972 RS14985
gene id: 67345:CP972_RS14985
uniprot id: A0A5J6H178
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

67345:CP972 RS19840
gene id: 67345:CP972_RS19840
uniprot id: A0A5J6H4K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

67345:CP972 RS23640
gene id: 67345:CP972_RS23640
uniprot id: A0A5J6H0V1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS24785
gene id: 67345:CP972_RS24785
uniprot id: A0A5J6HAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS06480
gene id: 67345:CP972_RS06480
uniprot id: A0A5J6GYQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS05835
gene id: 67345:CP972_RS05835
uniprot id: A0A5J6GWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS32230
gene id: 67345:CP972_RS32230
uniprot id: A0A5J6HCU8
names: Subcellular Location Annotation
messages: Nucleus

67345:CP972 RS25435
gene id: 67345:CP972_RS25435
uniprot id: A0A5J6H1L3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

67345:CP972 RS04460
gene id: 67345:CP972_RS04460
uniprot id: A0A5J6GRT2
names: Similarity
messages: Belongs to the peptidase S11 family.

67345:CP972 RS08640
gene id: 67345:CP972_RS08640
uniprot id: A0A5J6H2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS24265
gene id: 67345:CP972_RS24265
uniprot id: A0A5J6H5J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

67345:CP972 RS25180
gene id: 67345:CP972_RS25180
uniprot id: A0A5J6H634
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

67345:CP972 RS26430
gene id: 67345:CP972_RS26430
uniprot id: A0A5J6H9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67345:CP972 RS24380
gene id: 67345:CP972_RS24380
uniprot id: A0A5J6HAA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

67345:CP972 RS33215
gene id: 67345:CP972_RS33215
uniprot id: A0A5J6H7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67345:CP972 RS27355
gene id: 67345:CP972_RS27355
uniprot id: A0A5J6H4Z3
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS20170
gene id: 67345:CP972_RS20170
uniprot id: A0A5J6GZA5
names: Similarity
messages: Belongs to the Nth/MutY family.

67345:CP972 RS28260
gene id: 67345:CP972_RS28260
uniprot id: A0A5J6H3I3
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

67345:CP972 RS18165
gene id: 67345:CP972_RS18165
uniprot id: A0A5J6H2S8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24275
gene id: 67345:CP972_RS24275
uniprot id: A0A5J6HA81
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

67345:CP972 RS05140
gene id: 67345:CP972_RS05140
uniprot id: A0A5J6GWQ6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

67345:CP972 RS22300
gene id: 67345:CP972_RS22300
uniprot id: A0A5J6H2Q3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS13840
gene id: 67345:CP972_RS13840
uniprot id: A0A5J6GWE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

67345:CP972 RS26510
gene id: 67345:CP972_RS26510
uniprot id: A0A5J6H227
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS31700
gene id: 67345:CP972_RS31700
uniprot id: A0A5J6H966
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

67345:CP972 RS15245
gene id: 67345:CP972_RS15245
uniprot id: A0A5J6H1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

67345:CP972 RS19745
gene id: 67345:CP972_RS19745
uniprot id: A0A5J6GZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

67345:CP972 RS17280
gene id: 67345:CP972_RS17280
uniprot id: A0A5J6H2H0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

67345:CP972 RS22970
gene id: 67345:CP972_RS22970
uniprot id: A0A5J6H306
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

67345:CP972 RS29990
gene id: 67345:CP972_RS29990
uniprot id: A0A5J6HCQ2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS24800
gene id: 67345:CP972_RS24800
uniprot id: A0A5J6H2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

67345:CP972 RS21345
gene id: 67345:CP972_RS21345
uniprot id: A0A5J6H6U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

67345:CP972 RS24160
gene id: 67345:CP972_RS24160
uniprot id: A0A5J6H131
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS13175
gene id: 67345:CP972_RS13175
uniprot id: A0A5J6GW54
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

67345:CP972 RS32585
gene id: 67345:CP972_RS32585
uniprot id: A0A5J6H5C6
names: Similarity
messages: Belongs to the peptidase S33 family.

67345:CP972 RS14535
gene id: 67345:CP972_RS14535
uniprot id: A0A5J6H2A9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67345:CP972 RS28485
gene id: 67345:CP972_RS28485
uniprot id: A0A5J6H3L3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

67345:CP972 RS16900
gene id: 67345:CP972_RS16900
uniprot id: A0A5J6H0G3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67345:CP972 RS29310
gene id: 67345:CP972_RS29310
uniprot id: A0A5J6H9D8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

67345:CP972 RS31985
gene id: 67345:CP972_RS31985
uniprot id: A0A5J6H5S9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

67345:CP972 RS20865
gene id: 67345:CP972_RS20865
uniprot id: A0A5J6H528
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

67345:CP972 RS05220
gene id: 67345:CP972_RS05220
uniprot id: A0A5J6GWE4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67345:CP972 RS23190
gene id: 67345:CP972_RS23190
uniprot id: A0A5J6H7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS02645
gene id: 67345:CP972_RS02645
uniprot id: A0A5J6HA93
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67345:CP972 RS33570
gene id: 67345:CP972_RS33570
uniprot id: A0A5J6H7W7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS25755
gene id: 67345:CP972_RS25755
uniprot id: A0A5J6H2W5
names: Similarity
messages: Belongs to the ribF family.

67345:CP972 RS31850
gene id: 67345:CP972_RS31850
uniprot id: A0A5J6HAC8
names: Similarity
messages: Belongs to the CapA family.

67345:CP972 RS24635
gene id: 67345:CP972_RS24635
uniprot id: A0A5J6H1A8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS14770
gene id: 67345:CP972_RS14770
uniprot id: A0A5J6H2D5
names: Similarity
messages: Belongs to the CFA/CMAS family.

67345:CP972 RS26015
gene id: 67345:CP972_RS26015
uniprot id: A0A5J6H6J9
names: Similarity
messages: Belongs to the FPG family.

67345:CP972 RS28970
gene id: 67345:CP972_RS28970
uniprot id: A0A5J6HC85
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS24415
gene id: 67345:CP972_RS24415
uniprot id: A0A5J6H5K8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

67345:CP972 RS30630
gene id: 67345:CP972_RS30630
uniprot id: A0A5J6H8M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS33555
gene id: 67345:CP972_RS33555
uniprot id: A0A5J6H9Y2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

67345:CP972 RS09080
gene id: 67345:CP972_RS09080
uniprot id: A0A5J6H2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

67345:CP972 RS21620
gene id: 67345:CP972_RS21620
uniprot id: A0A5J6H0N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

67345:CP972 RS28825
gene id: 67345:CP972_RS28825
uniprot id: A0A5J6H7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS21215
gene id: 67345:CP972_RS21215
uniprot id: A0A5J6H433
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

67345:CP972 RS00765
gene id: 67345:CP972_RS00765
uniprot id: A0A5J6GV00
names: Similarity
messages: Belongs to the peptidase S66 family.

67345:CP972 RS21960
gene id: 67345:CP972_RS21960
uniprot id: A0A5J6H5K9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

67345:CP972 RS24780
gene id: 67345:CP972_RS24780
uniprot id: A0A5J6H711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS21905
gene id: 67345:CP972_RS21905
uniprot id: A0A5J6H5J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

67345:CP972 RS09650
gene id: 67345:CP972_RS09650
uniprot id: A0A5J6GZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

67345:CP972 RS20720
gene id: 67345:CP972_RS20720
uniprot id: A0A5J6H6J7
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS13955
gene id: 67345:CP972_RS13955
uniprot id: A0A5J6H0R1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

67345:CP972 RS27960
gene id: 67345:CP972_RS27960
uniprot id: A0A5J6H589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS09815
gene id: 67345:CP972_RS09815
uniprot id: A0A5J6GXA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS27190
gene id: 67345:CP972_RS27190
uniprot id: A0A5J6H833
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS30970
gene id: 67345:CP972_RS30970
uniprot id: A0A5J6H8V7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67345:CP972 RS30990
gene id: 67345:CP972_RS30990
uniprot id: A0A5J6HD38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS26075
gene id: 67345:CP972_RS26075
uniprot id: A0A5J6H6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS33660
gene id: 67345:CP972_RS33660
uniprot id: A0A5J6H6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

67345:CP972 RS20690
gene id: 67345:CP972_RS20690
uniprot id: A0A5J6H210
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

67345:CP972 RS05490
gene id: 67345:CP972_RS05490
uniprot id: A0A5J6GWK2
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS15865
gene id: 67345:CP972_RS15865
uniprot id: A0A5J6H1P7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS26935
gene id: 67345:CP972_RS26935
uniprot id: A0A5J6HA85
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67345:CP972 RS27040
gene id: 67345:CP972_RS27040
uniprot id: A0A5J6HA95
names: Similarity
messages: Belongs to the thioesterase family.

67345:CP972 RS23595
gene id: 67345:CP972_RS23595
uniprot id: A0A5J6H571
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS10655
gene id: 67345:CP972_RS10655
uniprot id: A0A5J6H0D3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

67345:CP972 RS33605
gene id: 67345:CP972_RS33605
uniprot id: A0A5J6H6X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67345:CP972 RS23175
gene id: 67345:CP972_RS23175
uniprot id: A0A5J6H635
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS07065
gene id: 67345:CP972_RS07065
uniprot id: A0A5J6GXN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

67345:CP972 RS11910
gene id: 67345:CP972_RS11910
uniprot id: A0A5J6H0X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

67345:CP972 RS25270
gene id: 67345:CP972_RS25270
uniprot id: A0A5J6H2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

67345:CP972 RS33550
gene id: 67345:CP972_RS33550
uniprot id: A0A5J6H5T1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67345:CP972 RS13095
gene id: 67345:CP972_RS13095
uniprot id: A0A5J6H4K0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS20780
gene id: 67345:CP972_RS20780
uniprot id: A0A5J6GZJ7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24070
gene id: 67345:CP972_RS24070
uniprot id: A0A5J6H6P7
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS26500
gene id: 67345:CP972_RS26500
uniprot id: A0A5J6H9L4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

67345:CP972 RS14695
gene id: 67345:CP972_RS14695
uniprot id: A0A5J6H195
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

67345:CP972 RS20760
gene id: 67345:CP972_RS20760
uniprot id: A0A5J6H891
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

67345:CP972 RS27240
gene id: 67345:CP972_RS27240
uniprot id: A0A5J6H879
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67345:CP972 RS06215
gene id: 67345:CP972_RS06215
uniprot id: A0A5J6GYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

67345:CP972 RS07975
gene id: 67345:CP972_RS07975
uniprot id: A0A5J6GZ01
names: Similarity
messages: Belongs to the UPF0098 family.

67345:CP972 RS03325
gene id: 67345:CP972_RS03325
uniprot id: A0A5J6GTS0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS25010
gene id: 67345:CP972_RS25010
uniprot id: A0A5J6H8R3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

67345:CP972 RS21325
gene id: 67345:CP972_RS21325
uniprot id: A0A5J6H455
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

67345:CP972 RS33415
gene id: 67345:CP972_RS33415
uniprot id: A0A5J6H5R5
names: Similarity
messages: Belongs to the cytochrome P450 family.

67345:CP972 RS04455
gene id: 67345:CP972_RS04455
uniprot id: A0A5J6GT09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24490
gene id: 67345:CP972_RS24490
uniprot id: A0A5J6HAC0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

67345:CP972 RS10960
gene id: 67345:CP972_RS10960
uniprot id: A0A5J6GZC5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67345:CP972 RS17580
gene id: 67345:CP972_RS17580
uniprot id: A0A5J6H2M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS28275
gene id: 67345:CP972_RS28275
uniprot id: A0A5J6H375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

67345:CP972 RS14345
gene id: 67345:CP972_RS14345
uniprot id: A0A5J6H5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

67345:CP972 RS21505
gene id: 67345:CP972_RS21505
uniprot id: A0A5J6H0L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

67345:CP972 RS10335
gene id: 67345:CP972_RS10335
uniprot id: A0A5J6GVQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

67345:CP972 RS24535
gene id: 67345:CP972_RS24535
uniprot id: A0A5J6H5R0
names: Similarity
messages: Belongs to the UPF0045 family.

67345:CP972 RS16925
gene id: 67345:CP972_RS16925
uniprot id: A0A5J6H4N0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS28860
gene id: 67345:CP972_RS28860
uniprot id: A0A5J6H3R6
names: Similarity
messages: Belongs to the Dps family.

67345:CP972 RS08520
gene id: 67345:CP972_RS08520
uniprot id: A0A5J6HAJ3
names: Similarity
messages: Belongs to the IlvD/Edd family.

67345:CP972 RS06935
gene id: 67345:CP972_RS06935
uniprot id: A0A5J6GU75
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS32335
gene id: 67345:CP972_RS32335
uniprot id: A0A5J6HAJ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67345:CP972 RS31245
gene id: 67345:CP972_RS31245
uniprot id: A0A5J6H4T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

67345:CP972 RS10195
gene id: 67345:CP972_RS10195
uniprot id: A0A5J6GVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS19200
gene id: 67345:CP972_RS19200
uniprot id: A0A5J6GZQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

67345:CP972 RS24730
gene id: 67345:CP972_RS24730
uniprot id: A0A5J6HAF7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67345:CP972 RS19930
gene id: 67345:CP972_RS19930
uniprot id: A0A5J6H988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67345:CP972 RS18590
gene id: 67345:CP972_RS18590
uniprot id: A0A5J6HBP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

67345:CP972 RS18170
gene id: 67345:CP972_RS18170
uniprot id: A0A5J6H3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

67345:CP972 RS21380
gene id: 67345:CP972_RS21380
uniprot id: A0A5J6H5B1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

67345:CP972 RS09485
gene id: 67345:CP972_RS09485
uniprot id: A0A5J6GYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

67345:CP972 RS09315
gene id: 67345:CP972_RS09315
uniprot id: A0A5J6GVL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

67345:CP972 RS19365
gene id: 67345:CP972_RS19365
uniprot id: A0A5J6H5U6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

67345:CP972 RS20700
gene id: 67345:CP972_RS20700
uniprot id: A0A5J6H3V7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

67345:CP972 RS21700
gene id: 67345:CP972_RS21700
uniprot id: A0A5J6H0N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67345:CP972 RS20045
gene id: 67345:CP972_RS20045
uniprot id: A0A5J6GZZ9
names: Subcellular Location Annotation
messages: Mitochondrion

67345:CP972 RS31965
gene id: 67345:CP972_RS31965
uniprot id: A0A5J6HAE7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

67345:CP972 RS09360
gene id: 67345:CP972_RS09360
uniprot id: A0A5J6HAS1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

67345:CP972 RS06230
gene id: 67345:CP972_RS06230
uniprot id: A0A5J6GXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

67345:CP972 RS25585
gene id: 67345:CP972_RS25585
uniprot id: A0A5J6H2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS14435
gene id: 67345:CP972_RS14435
uniprot id: A0A5J6H3B8
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS02075
gene id: 67345:CP972_RS02075
uniprot id: A0A5J6GUZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

67345:CP972 RS23845
gene id: 67345:CP972_RS23845
uniprot id: A0A5J6H5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67345:CP972 RS16860
gene id: 67345:CP972_RS16860
uniprot id: A0A5J6H396
names: Subcellular Location Annotation
messages: Cell membrane

67345:CP972 RS12520
gene id: 67345:CP972_RS12520
uniprot id: A0A5J6GWS2
names: Similarity
messages: Belongs to the peptidase S8 family.

67345:CP972 RS14040
gene id: 67345:CP972_RS14040
uniprot id: A0A5J6H349
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

67345:CP972 RS21945
gene id: 67345:CP972_RS21945
uniprot id: A0A5J6H2J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

67345:CP972 RS12350
gene id: 67345:CP972_RS12350
uniprot id: A0A5J6GVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

67345:CP972 RS19205
gene id: 67345:CP972_RS19205
uniprot id: A0A5J6GYW7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS08210
gene id: 67345:CP972_RS08210
uniprot id: A0A5J6GZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

67345:CP972 RS07600
gene id: 67345:CP972_RS07600
uniprot id: A0A5J6GW81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67345:CP972 RS13280
gene id: 67345:CP972_RS13280
uniprot id: A0A5J6GX46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

67345:CP972 RS26755
gene id: 67345:CP972_RS26755
uniprot id: A0A5J6HG21
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

67345:CP972 RS21815
gene id: 67345:CP972_RS21815
uniprot id: A0A5J6H4Q9
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS26115
gene id: 67345:CP972_RS26115
uniprot id: A0A5J6H1W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

67345:CP972 RS18815
gene id: 67345:CP972_RS18815
uniprot id: A0A5J6H377
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS28510
gene id: 67345:CP972_RS28510
uniprot id: A0A5J6HFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS25415
gene id: 67345:CP972_RS25415
uniprot id: A0A5J6H2C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

67345:CP972 RS27305
gene id: 67345:CP972_RS27305
uniprot id: A0A5J6H722
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS22435
gene id: 67345:CP972_RS22435
uniprot id: A0A5J6H4N3
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

67345:CP972 RS20745
gene id: 67345:CP972_RS20745
uniprot id: A0A5J6H219
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

67345:CP972 RS01455
gene id: 67345:CP972_RS01455
uniprot id: A0A5J6GS62
names: Similarity
messages: Belongs to the asparagine synthetase family.

67345:CP972 RS15000
gene id: 67345:CP972_RS15000
uniprot id: A0A5J6GZL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS17930
gene id: 67345:CP972_RS17930
uniprot id: A0A5J6H2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

67345:CP972 RS12360
gene id: 67345:CP972_RS12360
uniprot id: A0A5J6GZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

67345:CP972 RS05415
gene id: 67345:CP972_RS05415
uniprot id: A0A5J6GTG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS22395
gene id: 67345:CP972_RS22395
uniprot id: A0A5J6H0Y7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

67345:CP972 RS14485
gene id: 67345:CP972_RS14485
uniprot id: A0A5J6GXM4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67345:CP972 RS07015
gene id: 67345:CP972_RS07015
uniprot id: A0A5J6GXM7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67345:CP972 RS13900
gene id: 67345:CP972_RS13900
uniprot id: A0A5J6H0Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

67345:CP972 RS12305
gene id: 67345:CP972_RS12305
uniprot id: A0A5J6GZY0
names: Similarity
messages: Belongs to the Fur family.

67345:CP972 RS33245
gene id: 67345:CP972_RS33245
uniprot id: A0A5J6H6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67345:CP972 RS16285
gene id: 67345:CP972_RS16285
uniprot id: A0A5J6H2Z2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

67345:CP972 RS22740
gene id: 67345:CP972_RS22740
uniprot id: A0A5J6H4T6
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS20290
gene id: 67345:CP972_RS20290
uniprot id: A0A5J6H086
names: Similarity
messages: Belongs to the histone deacetylase family.

67345:CP972 RS06505
gene id: 67345:CP972_RS06505
uniprot id: A0A5J6GVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

67345:CP972 RS13235
gene id: 67345:CP972_RS13235
uniprot id: A0A5J6GW63
names: Similarity
messages: Belongs to the group II decarboxylase family.

67345:CP972 RS07885
gene id: 67345:CP972_RS07885
uniprot id: A0A5J6GXV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS00515
gene id: 67345:CP972_RS00515
uniprot id: A0A5J6GUY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

67345:CP972 RS15275
gene id: 67345:CP972_RS15275
uniprot id: A0A5J6GX12
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

67345:CP972 RS15820
gene id: 67345:CP972_RS15820
uniprot id: A0A5J6H1H7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS22905
gene id: 67345:CP972_RS22905
uniprot id: A0A5J6H0H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

67345:CP972 RS16670
gene id: 67345:CP972_RS16670
uniprot id: A0A5J6H289
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

67345:CP972 RS33755
gene id: 67345:CP972_RS33755
uniprot id: A0A5J6HA62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS09775
gene id: 67345:CP972_RS09775
uniprot id: A0A5J6GVP4
names: Similarity
messages: Belongs to the peptidase C40 family.

67345:CP972 RS33280
gene id: 67345:CP972_RS33280
uniprot id: A0A5J6HE72
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

67345:CP972 RS31970
gene id: 67345:CP972_RS31970
uniprot id: A0A5J6HDJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

67345:CP972 RS21220
gene id: 67345:CP972_RS21220
uniprot id: A0A5J6H577
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

67345:CP972 RS33180
gene id: 67345:CP972_RS33180
uniprot id: A0A5J6HE47
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

67345:CP972 RS20990
gene id: 67345:CP972_RS20990
uniprot id: A0A5J6H407
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

67345:CP972 RS26140
gene id: 67345:CP972_RS26140
uniprot id: A0A5J6H6I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67345:CP972 RS24920
gene id: 67345:CP972_RS24920
uniprot id: A0A5J6H1E7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

67345:CP972 RS20740
gene id: 67345:CP972_RS20740
uniprot id: A0A5J6H3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67345:CP972 RS24190
gene id: 67345:CP972_RS24190
uniprot id: A0A5J6HFH6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67345:CP972 RS06575
gene id: 67345:CP972_RS06575
uniprot id: A0A5J6H1J4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

67345:CP972 RS05345
gene id: 67345:CP972_RS05345
uniprot id: A0A5J6GXR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67345:CP972 RS17415
gene id: 67345:CP972_RS17415
uniprot id: A0A5J6H2J2
names: Subcellular Location Annotation
messages: Cytoplasm

67345:CP972 RS10520
gene id: 67345:CP972_RS10520
uniprot id: A0A5J6H3A7
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24750
gene id: 67345:CP972_RS24750
uniprot id: A0A5J6H1C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

67345:CP972 RS05985
gene id: 67345:CP972_RS05985
uniprot id: A0A5J6GSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67345:CP972 RS13245
gene id: 67345:CP972_RS13245
uniprot id: A0A5J6H0D6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

67345:CP972 RS30820
gene id: 67345:CP972_RS30820
uniprot id: A0A5J6H572
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67345:CP972 RS19715
gene id: 67345:CP972_RS19715
uniprot id: A0A5J6H1L4
names: Subcellular Location Annotation
messages: Membrane

67345:CP972 RS24345
gene id: 67345:CP972_RS24345
uniprot id: A0A5J6H291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

67345:CP972 RS07880
gene id: 67345:CP972_RS07880
uniprot id: A0A5J6HAU0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

67345:CP972 RS26400
gene id: 67345:CP972_RS26400
uniprot id: A0A5J6H6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

67345:CP972 RS02555
gene id: 67345:CP972_RS02555
uniprot id: A0A5J6GQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

67345:CP972 RS14630
gene id: 67345:CP972_RS14630
uniprot id: A0A5J6H116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane