666510:ASAC RS07025
gene id: 666510:ASAC_RS07025
uniprot id: D9PZ05
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

666510:ASAC RS03920
gene id: 666510:ASAC_RS03920
uniprot id: D9Q1J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

666510:ASAC RS05000
gene id: 666510:ASAC_RS05000
uniprot id: D9Q259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

666510:ASAC RS05175
gene id: 666510:ASAC_RS05175
uniprot id: D9Q292
names: Similarity
messages: Belongs to the PrpD family.

666510:ASAC RS06335
gene id: 666510:ASAC_RS06335
uniprot id: D9Q2W6
names: Similarity
messages: Belongs to the AOR/FOR family.

666510:ASAC RS01570
gene id: 666510:ASAC_RS01570
uniprot id: D9Q074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

666510:ASAC RS01620
gene id: 666510:ASAC_RS01620
uniprot id: D9Q084
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

666510:ASAC RS06610
gene id: 666510:ASAC_RS06610
uniprot id: D9Q320
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05475
gene id: 666510:ASAC_RS05475
uniprot id: D9Q2E8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

666510:ASAC RS00650
gene id: 666510:ASAC_RS00650
uniprot id: D9PZQ0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

666510:ASAC RS02485
gene id: 666510:ASAC_RS02485
uniprot id: D9Q0Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

666510:ASAC RS06420
gene id: 666510:ASAC_RS06420
uniprot id: D9Q2Y3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

666510:ASAC RS06000
gene id: 666510:ASAC_RS06000
uniprot id: D9Q2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS06715
gene id: 666510:ASAC_RS06715
uniprot id: D9Q341
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

666510:ASAC RS01280
gene id: 666510:ASAC_RS01280
uniprot id: D9Q018
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

666510:ASAC RS04740
gene id: 666510:ASAC_RS04740
uniprot id: D9Q208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS02975
gene id: 666510:ASAC_RS02975
uniprot id: D9Q101
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

666510:ASAC RS07110
gene id: 666510:ASAC_RS07110
uniprot id: D9PZ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

666510:ASAC RS07460
gene id: 666510:ASAC_RS07460
uniprot id: D9PZ92
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

666510:ASAC RS03080
gene id: 666510:ASAC_RS03080
uniprot id: D9Q123
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04305
gene id: 666510:ASAC_RS04305
uniprot id: D9Q1S8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

666510:ASAC RS04170
gene id: 666510:ASAC_RS04170
uniprot id: D9Q1Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

666510:ASAC RS00235
gene id: 666510:ASAC_RS00235
uniprot id: D9PZG9
names: Similarity
messages: Belongs to the peptidase S9C family.

666510:ASAC RS04910
gene id: 666510:ASAC_RS04910
uniprot id: D9Q241
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

666510:ASAC RS04815
gene id: 666510:ASAC_RS04815
uniprot id: D9Q222
names: Similarity
messages: Belongs to the HerA family.

666510:ASAC RS06105
gene id: 666510:ASAC_RS06105
uniprot id: D9Q2S0
names: Similarity
messages: Belongs to the HMBS family.

666510:ASAC RS02145
gene id: 666510:ASAC_RS02145
uniprot id: D9Q0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

666510:ASAC RS06095
gene id: 666510:ASAC_RS06095
uniprot id: D9Q2R8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

666510:ASAC RS07355
gene id: 666510:ASAC_RS07355
uniprot id: D9PZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

666510:ASAC RS02440
gene id: 666510:ASAC_RS02440
uniprot id: D9Q0P5
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04365
gene id: 666510:ASAC_RS04365
uniprot id: D9Q1T9
names: Similarity
messages: Belongs to the citrate synthase family.

666510:ASAC RS01145
gene id: 666510:ASAC_RS01145
uniprot id: D9PZZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

666510:ASAC RS01185
gene id: 666510:ASAC_RS01185
uniprot id: D9PZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

666510:ASAC RS00140
gene id: 666510:ASAC_RS00140
uniprot id: D9PZF0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

666510:ASAC RS00660
gene id: 666510:ASAC_RS00660
uniprot id: D9PZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

666510:ASAC RS03730
gene id: 666510:ASAC_RS03730
uniprot id: D9Q1G1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

666510:ASAC RS02130
gene id: 666510:ASAC_RS02130
uniprot id: D9Q0I2
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05565
gene id: 666510:ASAC_RS05565
uniprot id: D9Q2G6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

666510:ASAC RS06150
gene id: 666510:ASAC_RS06150
uniprot id: D9Q2T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS02210
gene id: 666510:ASAC_RS02210
uniprot id: D9Q0J9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

666510:ASAC RS01510
gene id: 666510:ASAC_RS01510
uniprot id: D9Q062
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

666510:ASAC RS04660
gene id: 666510:ASAC_RS04660
uniprot id: D9Q1Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

666510:ASAC RS06510
gene id: 666510:ASAC_RS06510
uniprot id: D9Q301
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04790
gene id: 666510:ASAC_RS04790
uniprot id: D9Q217
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

666510:ASAC RS00170
gene id: 666510:ASAC_RS00170
uniprot id: D9PZF6
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS02945
gene id: 666510:ASAC_RS02945
uniprot id: D9Q0Z5
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04580
gene id: 666510:ASAC_RS04580
uniprot id: D9Q1X8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

666510:ASAC RS03515
gene id: 666510:ASAC_RS03515
uniprot id: D9Q1B6
names: Similarity
messages: Belongs to the AOR/FOR family.

666510:ASAC RS07310
gene id: 666510:ASAC_RS07310
uniprot id: D9PZ61
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

666510:ASAC RS00800
gene id: 666510:ASAC_RS00800
uniprot id: D9PZS9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

666510:ASAC RS06215
gene id: 666510:ASAC_RS06215
uniprot id: D9Q2U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

666510:ASAC RS06210
gene id: 666510:ASAC_RS06210
uniprot id: D9Q2U2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

666510:ASAC RS01615
gene id: 666510:ASAC_RS01615
uniprot id: D9Q083
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

666510:ASAC RS07380
gene id: 666510:ASAC_RS07380
uniprot id: D9PZ76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

666510:ASAC RS05380
gene id: 666510:ASAC_RS05380
uniprot id: D9Q2D0
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

666510:ASAC RS07535
gene id: 666510:ASAC_RS07535
uniprot id: D9PZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

666510:ASAC RS05520
gene id: 666510:ASAC_RS05520
uniprot id: D9Q2F8
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

666510:ASAC RS02275
gene id: 666510:ASAC_RS02275
uniprot id: D9Q0L2
names: Similarity
messages: Belongs to the UPF0173 family.

666510:ASAC RS04965
gene id: 666510:ASAC_RS04965
uniprot id: D9Q252
names: Similarity
messages: Belongs to the UPF0273 family.

666510:ASAC RS04220
gene id: 666510:ASAC_RS04220
uniprot id: D9Q1R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05795
gene id: 666510:ASAC_RS05795
uniprot id: D9Q2L1
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS00545
gene id: 666510:ASAC_RS00545
uniprot id: D9PZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

666510:ASAC RS01735
gene id: 666510:ASAC_RS01735
uniprot id: D9Q0A7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

666510:ASAC RS05775
gene id: 666510:ASAC_RS05775
uniprot id: D9Q2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

666510:ASAC RS01160
gene id: 666510:ASAC_RS01160
uniprot id: D9PZZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

666510:ASAC RS06235
gene id: 666510:ASAC_RS06235
uniprot id: D9Q2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

666510:ASAC RS00145
gene id: 666510:ASAC_RS00145
uniprot id: D9PZF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS03020
gene id: 666510:ASAC_RS03020
uniprot id: D9Q110
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS02040
gene id: 666510:ASAC_RS02040
uniprot id: D9Q0G3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS01030
gene id: 666510:ASAC_RS01030
uniprot id: D9PZW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

666510:ASAC RS01520
gene id: 666510:ASAC_RS01520
uniprot id: D9Q064
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

666510:ASAC RS00885
gene id: 666510:ASAC_RS00885
uniprot id: D9PZU4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

666510:ASAC RS05675
gene id: 666510:ASAC_RS05675
uniprot id: D9Q2I7
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

666510:ASAC RS04590
gene id: 666510:ASAC_RS04590
uniprot id: D9Q1Y0
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05080
gene id: 666510:ASAC_RS05080
uniprot id: D9Q275
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

666510:ASAC RS01700
gene id: 666510:ASAC_RS01700
uniprot id: D9Q0A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS00620
gene id: 666510:ASAC_RS00620
uniprot id: D9PZP4
names: Similarity
messages: Belongs to the glutamine synthetase family.

666510:ASAC RS02165
gene id: 666510:ASAC_RS02165
uniprot id: D9Q0I9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

666510:ASAC RS06750
gene id: 666510:ASAC_RS06750
uniprot id: D9Q348
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS06185
gene id: 666510:ASAC_RS06185
uniprot id: D9Q2T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

666510:ASAC RS00455
gene id: 666510:ASAC_RS00455
uniprot id: D9PZL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

666510:ASAC RS02255
gene id: 666510:ASAC_RS02255
uniprot id: D9Q0K7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

666510:ASAC RS05980
gene id: 666510:ASAC_RS05980
uniprot id: D9Q2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

666510:ASAC RS00595
gene id: 666510:ASAC_RS00595
uniprot id: D9PZN9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

666510:ASAC RS07005
gene id: 666510:ASAC_RS07005
uniprot id: D9PZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS01635
gene id: 666510:ASAC_RS01635
uniprot id: D9Q087
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS00240
gene id: 666510:ASAC_RS00240
uniprot id: D9PZH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

666510:ASAC RS03055
gene id: 666510:ASAC_RS03055
uniprot id: D9Q117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

666510:ASAC RS00915
gene id: 666510:ASAC_RS00915
uniprot id: D9PZU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

666510:ASAC RS01200
gene id: 666510:ASAC_RS01200
uniprot id: D9Q002
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

666510:ASAC RS00025
gene id: 666510:ASAC_RS00025
uniprot id: D9PZC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

666510:ASAC RS05300
gene id: 666510:ASAC_RS05300
uniprot id: D9Q2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Membrane

666510:ASAC RS05705
gene id: 666510:ASAC_RS05705
uniprot id: D9Q2J3
names: Similarity
messages: Belongs to the PDCD5 family.

666510:ASAC RS05995
gene id: 666510:ASAC_RS05995
uniprot id: D9Q2Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

666510:ASAC RS05185
gene id: 666510:ASAC_RS05185
uniprot id: D9Q294
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS03645
gene id: 666510:ASAC_RS03645
uniprot id: D9Q1E4
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS06545
gene id: 666510:ASAC_RS06545
uniprot id: D9Q308
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS05430
gene id: 666510:ASAC_RS05430
uniprot id: D9Q2D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

666510:ASAC RS02335
gene id: 666510:ASAC_RS02335
uniprot id: D9Q0M4
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

666510:ASAC RS06225
gene id: 666510:ASAC_RS06225
uniprot id: D9Q2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

666510:ASAC RS06305
gene id: 666510:ASAC_RS06305
uniprot id: D9Q2W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

666510:ASAC RS07510
gene id: 666510:ASAC_RS07510
uniprot id: D9PZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

666510:ASAC RS00020
gene id: 666510:ASAC_RS00020
uniprot id: D9PZC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

666510:ASAC RS07285
gene id: 666510:ASAC_RS07285
uniprot id: D9PZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

666510:ASAC RS06900
gene id: 666510:ASAC_RS06900
uniprot id: D9PYY0
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

666510:ASAC RS07165
gene id: 666510:ASAC_RS07165
uniprot id: D9PZ33
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

666510:ASAC RS01150
gene id: 666510:ASAC_RS01150
uniprot id: D9PZZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS02395
gene id: 666510:ASAC_RS02395
uniprot id: D9Q0N6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

666510:ASAC RS05085
gene id: 666510:ASAC_RS05085
uniprot id: D9Q276
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS05220
gene id: 666510:ASAC_RS05220
uniprot id: D9Q2A0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

666510:ASAC RS01215
gene id: 666510:ASAC_RS01215
uniprot id: D9Q005
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS04770
gene id: 666510:ASAC_RS04770
uniprot id: D9Q213
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

666510:ASAC RS01255
gene id: 666510:ASAC_RS01255
uniprot id: D9Q013
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

666510:ASAC RS02005
gene id: 666510:ASAC_RS02005
uniprot id: D9Q0F6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

666510:ASAC RS04655
gene id: 666510:ASAC_RS04655
uniprot id: D9Q1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

666510:ASAC RS00330
gene id: 666510:ASAC_RS00330
uniprot id: D9PZI8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS03990
gene id: 666510:ASAC_RS03990
uniprot id: D9Q1L4
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

666510:ASAC RS05105
gene id: 666510:ASAC_RS05105
uniprot id: D9Q280
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

666510:ASAC RS06200
gene id: 666510:ASAC_RS06200
uniprot id: D9Q2U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

666510:ASAC RS05200
gene id: 666510:ASAC_RS05200
uniprot id: D9Q297
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

666510:ASAC RS04805
gene id: 666510:ASAC_RS04805
uniprot id: D9Q220
names: Similarity
messages: Belongs to the AAA ATPase family.

666510:ASAC RS02860
gene id: 666510:ASAC_RS02860
uniprot id: D9Q0X8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS04005
gene id: 666510:ASAC_RS04005
uniprot id: D9Q1L7
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04255
gene id: 666510:ASAC_RS04255
uniprot id: D9Q1R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

666510:ASAC RS04130
gene id: 666510:ASAC_RS04130
uniprot id: D9Q1P3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

666510:ASAC RS00725
gene id: 666510:ASAC_RS00725
uniprot id: D9PZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

666510:ASAC RS04875
gene id: 666510:ASAC_RS04875
uniprot id: D9Q234
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS01405
gene id: 666510:ASAC_RS01405
uniprot id: D9Q041
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS02780
gene id: 666510:ASAC_RS02780
uniprot id: D9Q0W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

666510:ASAC RS01770
gene id: 666510:ASAC_RS01770
uniprot id: D9Q0B4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

666510:ASAC RS00555
gene id: 666510:ASAC_RS00555
uniprot id: D9PZN2
names: Similarity
messages: Belongs to the Ahb/Nir family.

666510:ASAC RS02025
gene id: 666510:ASAC_RS02025
uniprot id: D9Q0G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

666510:ASAC RS01390
gene id: 666510:ASAC_RS01390
uniprot id: D9Q039
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04040
gene id: 666510:ASAC_RS04040
uniprot id: D9Q1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS01260
gene id: 666510:ASAC_RS01260
uniprot id: D9Q014
names: Similarity
messages: Belongs to the AOR/FOR family.

666510:ASAC RS05555
gene id: 666510:ASAC_RS05555
uniprot id: D9Q2G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

666510:ASAC RS02940
gene id: 666510:ASAC_RS02940
uniprot id: D9Q0Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05090
gene id: 666510:ASAC_RS05090
uniprot id: D9Q277
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

666510:ASAC RS03010
gene id: 666510:ASAC_RS03010
uniprot id: D9Q108
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

666510:ASAC RS01610
gene id: 666510:ASAC_RS01610
uniprot id: D9Q082
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

666510:ASAC RS05780
gene id: 666510:ASAC_RS05780
uniprot id: D9Q2K7
names: Similarity
messages: Belongs to the SDO1/SBDS family.

666510:ASAC RS05765
gene id: 666510:ASAC_RS05765
uniprot id: D9Q2K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

666510:ASAC RS05095
gene id: 666510:ASAC_RS05095
uniprot id: D9Q278
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

666510:ASAC RS03145
gene id: 666510:ASAC_RS03145
uniprot id: D9Q136
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS01415
gene id: 666510:ASAC_RS01415
uniprot id: D9Q043
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

666510:ASAC RS05160
gene id: 666510:ASAC_RS05160
uniprot id: D9Q289
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

666510:ASAC RS07950
gene id: 666510:ASAC_RS07950
uniprot id: D9Q2C2
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

666510:ASAC RS04640
gene id: 666510:ASAC_RS04640
uniprot id: D9Q1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

666510:ASAC RS04795
gene id: 666510:ASAC_RS04795
uniprot id: D9Q218
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

666510:ASAC RS07315
gene id: 666510:ASAC_RS07315
uniprot id: D9PZ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

666510:ASAC RS06345
gene id: 666510:ASAC_RS06345
uniprot id: D9Q2W8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

666510:ASAC RS00490
gene id: 666510:ASAC_RS00490
uniprot id: D9PZM0
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS00480
gene id: 666510:ASAC_RS00480
uniprot id: D9PZL8
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS06365
gene id: 666510:ASAC_RS06365
uniprot id: D9Q2X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

666510:ASAC RS01485
gene id: 666510:ASAC_RS01485
uniprot id: D9Q057
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

666510:ASAC RS01420
gene id: 666510:ASAC_RS01420
uniprot id: D9Q044
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05100
gene id: 666510:ASAC_RS05100
uniprot id: D9Q279
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

666510:ASAC RS02555
gene id: 666510:ASAC_RS02555
uniprot id: D9Q0R7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

666510:ASAC RS00015
gene id: 666510:ASAC_RS00015
uniprot id: D9PZC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

666510:ASAC RS05580
gene id: 666510:ASAC_RS05580
uniprot id: D9Q2G9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS04010
gene id: 666510:ASAC_RS04010
uniprot id: D9Q1L8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS06780
gene id: 666510:ASAC_RS06780
uniprot id: D9Q354
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

666510:ASAC RS05715
gene id: 666510:ASAC_RS05715
uniprot id: D9Q2J6
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

666510:ASAC RS01165
gene id: 666510:ASAC_RS01165
uniprot id: D9PZZ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

666510:ASAC RS04165
gene id: 666510:ASAC_RS04165
uniprot id: D9Q1Q0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

666510:ASAC RS04645
gene id: 666510:ASAC_RS04645
uniprot id: D9Q1Z0
names: Similarity
messages: Belongs to the MCM family.

666510:ASAC RS05595
gene id: 666510:ASAC_RS05595
uniprot id: D9Q2H2
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

666510:ASAC RS06455
gene id: 666510:ASAC_RS06455
uniprot id: D9Q2Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

666510:ASAC RS05640
gene id: 666510:ASAC_RS05640
uniprot id: D9Q2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

666510:ASAC RS04630
gene id: 666510:ASAC_RS04630
uniprot id: D9Q1Y8
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

666510:ASAC RS04360
gene id: 666510:ASAC_RS04360
uniprot id: D9Q1T8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS03590
gene id: 666510:ASAC_RS03590
uniprot id: D9Q1D1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

666510:ASAC RS00515
gene id: 666510:ASAC_RS00515
uniprot id: D9PZM4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

666510:ASAC RS05755
gene id: 666510:ASAC_RS05755
uniprot id: D9Q2K2
names: Function
messages: Probably involved in the biogenesis of the ribosome.

666510:ASAC RS04505
gene id: 666510:ASAC_RS04505
uniprot id: D9Q1W4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

666510:ASAC RS07075
gene id: 666510:ASAC_RS07075
uniprot id: D9PZ15
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

666510:ASAC RS05075
gene id: 666510:ASAC_RS05075
uniprot id: D9Q274
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

666510:ASAC RS04925
gene id: 666510:ASAC_RS04925
uniprot id: D9Q244
names: Similarity
messages: Belongs to the group II decarboxylase family.

666510:ASAC RS05695
gene id: 666510:ASAC_RS05695
uniprot id: D9Q2J1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

666510:ASAC RS07455
gene id: 666510:ASAC_RS07455
uniprot id: D9PZ91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

666510:ASAC RS00685
gene id: 666510:ASAC_RS00685
uniprot id: D9PZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

666510:ASAC RS01170
gene id: 666510:ASAC_RS01170
uniprot id: D9PZZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

666510:ASAC RS05880
gene id: 666510:ASAC_RS05880
uniprot id: D9Q2M8
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

666510:ASAC RS06870
gene id: 666510:ASAC_RS06870
uniprot id: D9Q373
names: Caution
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS07430
gene id: 666510:ASAC_RS07430
uniprot id: D9PZ86
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

666510:ASAC RS01705
gene id: 666510:ASAC_RS01705
uniprot id: D9Q0A1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

666510:ASAC RS01600
gene id: 666510:ASAC_RS01600
uniprot id: D9Q080
names: Similarity
messages: Belongs to the carbamate kinase family.

666510:ASAC RS07010
gene id: 666510:ASAC_RS07010
uniprot id: D9PZ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS02085
gene id: 666510:ASAC_RS02085
uniprot id: D9Q0H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

666510:ASAC RS05235
gene id: 666510:ASAC_RS05235
uniprot id: D9Q2A2
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

666510:ASAC RS00380
gene id: 666510:ASAC_RS00380
uniprot id: D9PZJ7
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

666510:ASAC RS03155
gene id: 666510:ASAC_RS03155
uniprot id: D9Q138
names: Similarity
messages: Belongs to the glutaredoxin family.

666510:ASAC RS01385
gene id: 666510:ASAC_RS01385
uniprot id: D9Q038
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

666510:ASAC RS02480
gene id: 666510:ASAC_RS02480
uniprot id: D9Q0Q2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

666510:ASAC RS03525
gene id: 666510:ASAC_RS03525
uniprot id: D9Q1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

666510:ASAC RS00945
gene id: 666510:ASAC_RS00945
uniprot id: D9PZV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

666510:ASAC RS00695
gene id: 666510:ASAC_RS00695
uniprot id: D9PZQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

666510:ASAC RS07130
gene id: 666510:ASAC_RS07130
uniprot id: D9PZ26
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

666510:ASAC RS01445
gene id: 666510:ASAC_RS01445
uniprot id: D9Q049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

666510:ASAC RS01650
gene id: 666510:ASAC_RS01650
uniprot id: D9Q090
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

666510:ASAC RS06630
gene id: 666510:ASAC_RS06630
uniprot id: D9Q324
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

666510:ASAC RS00350
gene id: 666510:ASAC_RS00350
uniprot id: D9PZJ2
names: Similarity
messages: Belongs to the SfsA family.

666510:ASAC RS04135
gene id: 666510:ASAC_RS04135
uniprot id: D9Q1P4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

666510:ASAC RS03570
gene id: 666510:ASAC_RS03570
uniprot id: D9Q1C7
names: Subcellular Location Annotation
messages: Encapsulin nanocompartment

666510:ASAC RS05330
gene id: 666510:ASAC_RS05330
uniprot id: D9Q2C0
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS01665
gene id: 666510:ASAC_RS01665
uniprot id: D9Q093
names: Similarity
messages: Belongs to the HypE family.

666510:ASAC RS01585
gene id: 666510:ASAC_RS01585
uniprot id: D9Q077
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS02375
gene id: 666510:ASAC_RS02375
uniprot id: D9Q0N2
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS02270
gene id: 666510:ASAC_RS02270
uniprot id: D9Q0L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

666510:ASAC RS01710
gene id: 666510:ASAC_RS01710
uniprot id: D9Q0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

666510:ASAC RS00290
gene id: 666510:ASAC_RS00290
uniprot id: D9PZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS07155
gene id: 666510:ASAC_RS07155
uniprot id: D9PZ31
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS00980
gene id: 666510:ASAC_RS00980
uniprot id: D9PZW0
names: Similarity
messages: Belongs to the UPF0201 family.

666510:ASAC RS06250
gene id: 666510:ASAC_RS06250
uniprot id: D9Q2V0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

666510:ASAC RS06980
gene id: 666510:ASAC_RS06980
uniprot id: D9PYZ5
names: Similarity
messages: Belongs to the UPF0215 family.

666510:ASAC RS02150
gene id: 666510:ASAC_RS02150
uniprot id: D9Q0I6
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

666510:ASAC RS02095
gene id: 666510:ASAC_RS02095
uniprot id: D9Q0H5
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

666510:ASAC RS00690
gene id: 666510:ASAC_RS00690
uniprot id: D9PZQ8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

666510:ASAC RS01195
gene id: 666510:ASAC_RS01195
uniprot id: D9Q001
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS00390
gene id: 666510:ASAC_RS00390
uniprot id: D9PZJ9
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05335
gene id: 666510:ASAC_RS05335
uniprot id: D9Q2C1
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS02185
gene id: 666510:ASAC_RS02185
uniprot id: D9Q0J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

666510:ASAC RS05495
gene id: 666510:ASAC_RS05495
uniprot id: D9Q2F2
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05990
gene id: 666510:ASAC_RS05990
uniprot id: D9Q2P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS05145
gene id: 666510:ASAC_RS05145
uniprot id: D9Q286
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS04070
gene id: 666510:ASAC_RS04070
uniprot id: D9Q1N0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

666510:ASAC RS02160
gene id: 666510:ASAC_RS02160
uniprot id: D9Q0I8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

666510:ASAC RS04760
gene id: 666510:ASAC_RS04760
uniprot id: D9Q211
names: Similarity
messages: Belongs to the RutC family.

666510:ASAC RS02135
gene id: 666510:ASAC_RS02135
uniprot id: D9Q0I3
names: Similarity
messages: Belongs to the diphthine synthase family.

666510:ASAC RS01275
gene id: 666510:ASAC_RS01275
uniprot id: D9Q017
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

666510:ASAC RS01805
gene id: 666510:ASAC_RS01805
uniprot id: D9Q0C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

666510:ASAC RS01240
gene id: 666510:ASAC_RS01240
uniprot id: D9Q010
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

666510:ASAC RS06645
gene id: 666510:ASAC_RS06645
uniprot id: D9Q327
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

666510:ASAC RS03175
gene id: 666510:ASAC_RS03175
uniprot id: D9Q142
names: Similarity
messages: Belongs to the RuvB family.

666510:ASAC RS05620
gene id: 666510:ASAC_RS05620
uniprot id: D9Q2H6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

666510:ASAC RS02770
gene id: 666510:ASAC_RS02770
uniprot id: D9Q0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

666510:ASAC RS05535
gene id: 666510:ASAC_RS05535
uniprot id: D9Q2G1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

666510:ASAC RS03710
gene id: 666510:ASAC_RS03710
uniprot id: D9Q1F7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

666510:ASAC RS07800
gene id: 666510:ASAC_RS07800
uniprot id: D9Q291
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

666510:ASAC RS05410
gene id: 666510:ASAC_RS05410
uniprot id: D9Q2D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

666510:ASAC RS07070
gene id: 666510:ASAC_RS07070
uniprot id: D9PZ14
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

666510:ASAC RS00605
gene id: 666510:ASAC_RS00605
uniprot id: D9PZP1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

666510:ASAC RS00295
gene id: 666510:ASAC_RS00295
uniprot id: D9PZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS05970
gene id: 666510:ASAC_RS05970
uniprot id: D9Q2P5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

666510:ASAC RS00435
gene id: 666510:ASAC_RS00435
uniprot id: D9PZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS04895
gene id: 666510:ASAC_RS04895
uniprot id: D9Q238
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05975
gene id: 666510:ASAC_RS05975
uniprot id: D9Q2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

666510:ASAC RS04710
gene id: 666510:ASAC_RS04710
uniprot id: D9Q202
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

666510:ASAC RS02585
gene id: 666510:ASAC_RS02585
uniprot id: D9Q0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

666510:ASAC RS00965
gene id: 666510:ASAC_RS00965
uniprot id: D9PZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

666510:ASAC RS04285
gene id: 666510:ASAC_RS04285
uniprot id: D9Q1S4
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05770
gene id: 666510:ASAC_RS05770
uniprot id: D9Q2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

666510:ASAC RS04955
gene id: 666510:ASAC_RS04955
uniprot id: D9Q250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS05835
gene id: 666510:ASAC_RS05835
uniprot id: D9Q2L9
names: Similarity
messages: Belongs to the UPF0047 family.

666510:ASAC RS03015
gene id: 666510:ASAC_RS03015
uniprot id: D9Q109
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

666510:ASAC RS02315
gene id: 666510:ASAC_RS02315
uniprot id: D9Q0M0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05530
gene id: 666510:ASAC_RS05530
uniprot id: D9Q2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

666510:ASAC RS04960
gene id: 666510:ASAC_RS04960
uniprot id: D9Q251
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS03135
gene id: 666510:ASAC_RS03135
uniprot id: D9Q134
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

666510:ASAC RS03750
gene id: 666510:ASAC_RS03750
uniprot id: D9Q1G5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

666510:ASAC RS06350
gene id: 666510:ASAC_RS06350
uniprot id: D9Q2W9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

666510:ASAC RS07645
gene id: 666510:ASAC_RS07645
uniprot id: D9Q1U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

666510:ASAC RS05815
gene id: 666510:ASAC_RS05815
uniprot id: D9Q2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

666510:ASAC RS06550
gene id: 666510:ASAC_RS06550
uniprot id: D9Q309
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS02790
gene id: 666510:ASAC_RS02790
uniprot id: D9Q0W4
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

666510:ASAC RS02030
gene id: 666510:ASAC_RS02030
uniprot id: D9Q0G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

666510:ASAC RS00950
gene id: 666510:ASAC_RS00950
uniprot id: D9PZV4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

666510:ASAC RS05700
gene id: 666510:ASAC_RS05700
uniprot id: D9Q2J2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

666510:ASAC RS02390
gene id: 666510:ASAC_RS02390
uniprot id: D9Q0N5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

666510:ASAC RS04075
gene id: 666510:ASAC_RS04075
uniprot id: D9Q1N1
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

666510:ASAC RS01040
gene id: 666510:ASAC_RS01040
uniprot id: D9PZX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

666510:ASAC RS06330
gene id: 666510:ASAC_RS06330
uniprot id: D9Q2W5
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

666510:ASAC RS05585
gene id: 666510:ASAC_RS05585
uniprot id: D9Q2H0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

666510:ASAC RS02455
gene id: 666510:ASAC_RS02455
uniprot id: D9Q0P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

666510:ASAC RS02750
gene id: 666510:ASAC_RS02750
uniprot id: D9Q0V6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

666510:ASAC RS05855
gene id: 666510:ASAC_RS05855
uniprot id: D9Q2M3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

666510:ASAC RS01140
gene id: 666510:ASAC_RS01140
uniprot id: D9PZZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

666510:ASAC RS01135
gene id: 666510:ASAC_RS01135
uniprot id: D9PZY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

666510:ASAC RS01175
gene id: 666510:ASAC_RS01175
uniprot id: D9PZZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

666510:ASAC RS02890
gene id: 666510:ASAC_RS02890
uniprot id: D9Q0Y4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

666510:ASAC RS05375
gene id: 666510:ASAC_RS05375
uniprot id: D9Q2C9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

666510:ASAC RS01810
gene id: 666510:ASAC_RS01810
uniprot id: D9Q0C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

666510:ASAC RS01375
gene id: 666510:ASAC_RS01375
uniprot id: D9Q037
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

666510:ASAC RS02285
gene id: 666510:ASAC_RS02285
uniprot id: D9Q0L4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

666510:ASAC RS06705
gene id: 666510:ASAC_RS06705
uniprot id: D9Q339
names: Similarity
messages: Belongs to the Nth/MutY family.

666510:ASAC RS01695
gene id: 666510:ASAC_RS01695
uniprot id: D9Q099
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS03330
gene id: 666510:ASAC_RS03330
uniprot id: D9Q176
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

666510:ASAC RS04090
gene id: 666510:ASAC_RS04090
uniprot id: D9Q1N4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

666510:ASAC RS04550
gene id: 666510:ASAC_RS04550
uniprot id: D9Q1X2
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

666510:ASAC RS03725
gene id: 666510:ASAC_RS03725
uniprot id: D9Q1G0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

666510:ASAC RS06465
gene id: 666510:ASAC_RS06465
uniprot id: D9Q2Z2
names: Similarity
messages: Belongs to the HypE family.

666510:ASAC RS02875
gene id: 666510:ASAC_RS02875
uniprot id: D9Q0Y1
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS05290
gene id: 666510:ASAC_RS05290
uniprot id: D9Q2B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

666510:ASAC RS01915
gene id: 666510:ASAC_RS01915
uniprot id: D9Q0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

666510:ASAC RS00635
gene id: 666510:ASAC_RS00635
uniprot id: D9PZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

666510:ASAC RS05350
gene id: 666510:ASAC_RS05350
uniprot id: D9Q2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

666510:ASAC RS00700
gene id: 666510:ASAC_RS00700
uniprot id: D9PZR0
names: Similarity
messages: Belongs to the SUI1 family.

666510:ASAC RS06010
gene id: 666510:ASAC_RS06010
uniprot id: D9Q2Q2
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

666510:ASAC RS06325
gene id: 666510:ASAC_RS06325
uniprot id: D9Q2W4
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

666510:ASAC RS06970
gene id: 666510:ASAC_RS06970
uniprot id: D9PYZ3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

666510:ASAC RS07020
gene id: 666510:ASAC_RS07020
uniprot id: D9PZ04
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

666510:ASAC RS06945
gene id: 666510:ASAC_RS06945
uniprot id: D9PYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

666510:ASAC RS03880
gene id: 666510:ASAC_RS03880
uniprot id: D9Q1J0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

666510:ASAC RS06905
gene id: 666510:ASAC_RS06905
uniprot id: D9PYY1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

666510:ASAC RS00600
gene id: 666510:ASAC_RS00600
uniprot id: D9PZP0
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04515
gene id: 666510:ASAC_RS04515
uniprot id: D9Q1W6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

666510:ASAC RS02410
gene id: 666510:ASAC_RS02410
uniprot id: D9Q0N9
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS05730
gene id: 666510:ASAC_RS05730
uniprot id: D9Q2J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS03835
gene id: 666510:ASAC_RS03835
uniprot id: D9Q1I0
names: Similarity
messages: Belongs to the AOR/FOR family.

666510:ASAC RS02795
gene id: 666510:ASAC_RS02795
uniprot id: D9Q0W5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

666510:ASAC RS06140
gene id: 666510:ASAC_RS06140
uniprot id: D9Q2S8
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

666510:ASAC RS05445
gene id: 666510:ASAC_RS05445
uniprot id: D9Q2E2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

666510:ASAC RS01080
gene id: 666510:ASAC_RS01080
uniprot id: D9PZX8
names: Similarity
messages: Belongs to the glutaredoxin family.

666510:ASAC RS06190
gene id: 666510:ASAC_RS06190
uniprot id: D9Q2T8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

666510:ASAC RS00175
gene id: 666510:ASAC_RS00175
uniprot id: D9PZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

666510:ASAC RS03720
gene id: 666510:ASAC_RS03720
uniprot id: D9Q1F9
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS03885
gene id: 666510:ASAC_RS03885
uniprot id: D9Q1J1
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04585
gene id: 666510:ASAC_RS04585
uniprot id: D9Q1X9
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS01940
gene id: 666510:ASAC_RS01940
uniprot id: D9Q0E3
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS01965
gene id: 666510:ASAC_RS01965
uniprot id: D9Q0E8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS01950
gene id: 666510:ASAC_RS01950
uniprot id: D9Q0E5
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS00485
gene id: 666510:ASAC_RS00485
uniprot id: D9PZL9
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

666510:ASAC RS06320
gene id: 666510:ASAC_RS06320
uniprot id: D9Q2W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

666510:ASAC RS04990
gene id: 666510:ASAC_RS04990
uniprot id: D9Q257
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.

666510:ASAC RS01270
gene id: 666510:ASAC_RS01270
uniprot id: D9Q016
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

666510:ASAC RS05630
gene id: 666510:ASAC_RS05630
uniprot id: D9Q2H8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

666510:ASAC RS02055
gene id: 666510:ASAC_RS02055
uniprot id: D9Q0G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS02105
gene id: 666510:ASAC_RS02105
uniprot id: D9Q0H8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS00530
gene id: 666510:ASAC_RS00530
uniprot id: D9PZM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

666510:ASAC RS05960
gene id: 666510:ASAC_RS05960
uniprot id: D9Q2P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

666510:ASAC RS01660
gene id: 666510:ASAC_RS01660
uniprot id: D9Q092
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal MetE family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.

666510:ASAC RS01730
gene id: 666510:ASAC_RS01730
uniprot id: D9Q0A6
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

666510:ASAC RS05785
gene id: 666510:ASAC_RS05785
uniprot id: D9Q2K8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

666510:ASAC RS07420
gene id: 666510:ASAC_RS07420
uniprot id: D9PZ84
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04620
gene id: 666510:ASAC_RS04620
uniprot id: D9Q1Y6
names: Similarity
messages: Belongs to the peptidase M24B family.

666510:ASAC RS04125
gene id: 666510:ASAC_RS04125
uniprot id: D9Q1P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS03770
gene id: 666510:ASAC_RS03770
uniprot id: D9Q1G8
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS06915
gene id: 666510:ASAC_RS06915
uniprot id: D9PYY3
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

666510:ASAC RS04775
gene id: 666510:ASAC_RS04775
uniprot id: D9Q214
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

666510:ASAC RS01180
gene id: 666510:ASAC_RS01180
uniprot id: D9PZZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

666510:ASAC RS04625
gene id: 666510:ASAC_RS04625
uniprot id: D9Q1Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

666510:ASAC RS02565
gene id: 666510:ASAC_RS02565
uniprot id: D9Q0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

666510:ASAC RS01045
gene id: 666510:ASAC_RS01045
uniprot id: D9PZX2
names: Similarity
messages: Belongs to the eIF-2-alpha family.

666510:ASAC RS04155
gene id: 666510:ASAC_RS04155
uniprot id: D9Q1P8
names: Similarity
messages: Belongs to the CutA family.

666510:ASAC RS07335
gene id: 666510:ASAC_RS07335
uniprot id: D9PZ67
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS04600
gene id: 666510:ASAC_RS04600
uniprot id: D9Q1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

666510:ASAC RS03925
gene id: 666510:ASAC_RS03925
uniprot id: D9Q1K0
names: Subcellular Location Annotation
messages: Cell membrane

666510:ASAC RS02190
gene id: 666510:ASAC_RS02190
uniprot id: D9Q0J5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

666510:ASAC RS06745
gene id: 666510:ASAC_RS06745
uniprot id: D9Q347
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

666510:ASAC RS00640
gene id: 666510:ASAC_RS00640
uniprot id: D9PZP8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

666510:ASAC RS07190
gene id: 666510:ASAC_RS07190
uniprot id: D9PZ36
names: Subcellular Location Annotation
messages: Membrane

666510:ASAC RS02540
gene id: 666510:ASAC_RS02540
uniprot id: D9Q0R4
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

666510:ASAC RS00265
gene id: 666510:ASAC_RS00265
uniprot id: D9PZH5
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

666510:ASAC RS00985
gene id: 666510:ASAC_RS00985
uniprot id: D9PZW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

666510:ASAC RS02200
gene id: 666510:ASAC_RS02200
uniprot id: D9Q0J7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

666510:ASAC RS02650
gene id: 666510:ASAC_RS02650
uniprot id: D9Q0T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.