662476:KDQ40 RS09550
gene id: 662476:KDQ40_RS09550
uniprot id: M0JUJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14220
gene id: 662476:KDQ40_RS14220
uniprot id: M0K3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

662476:KDQ40 RS14335
gene id: 662476:KDQ40_RS14335
uniprot id: M0K0L4
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS02710
gene id: 662476:KDQ40_RS02710
uniprot id: M0K995
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

662476:KDQ40 RS15145
gene id: 662476:KDQ40_RS15145
uniprot id: M0K1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS17165
gene id: 662476:KDQ40_RS17165
uniprot id: M0JJ50
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS20835
gene id: 662476:KDQ40_RS20835
uniprot id: M0JRN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS17020
gene id: 662476:KDQ40_RS17020
uniprot id: M0JME9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19550
gene id: 662476:KDQ40_RS19550
uniprot id: M0JQR9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

662476:KDQ40 RS15315
gene id: 662476:KDQ40_RS15315
uniprot id: M0K2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

662476:KDQ40 RS19050
gene id: 662476:KDQ40_RS19050
uniprot id: M0JIF7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07035
gene id: 662476:KDQ40_RS07035
uniprot id: M0K1M2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

662476:KDQ40 RS06120
gene id: 662476:KDQ40_RS06120
uniprot id: M0JXA5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

662476:KDQ40 RS09490
gene id: 662476:KDQ40_RS09490
uniprot id: M0JXC6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS11875
gene id: 662476:KDQ40_RS11875
uniprot id: M0JT67
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

662476:KDQ40 RS12195
gene id: 662476:KDQ40_RS12195
uniprot id: M0JSU2
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS07770
gene id: 662476:KDQ40_RS07770
uniprot id: A0A8T8KHX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS09765
gene id: 662476:KDQ40_RS09765
uniprot id: M0JWC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02700
gene id: 662476:KDQ40_RS02700
uniprot id: M0K4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS13750
gene id: 662476:KDQ40_RS13750
uniprot id: M0K183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

662476:KDQ40 RS00575
gene id: 662476:KDQ40_RS00575
uniprot id: M0K345
names: Similarity
messages: Belongs to the AOR/FOR family.

662476:KDQ40 RS14970
gene id: 662476:KDQ40_RS14970
uniprot id: M0K4V1
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09285
gene id: 662476:KDQ40_RS09285
uniprot id: M0JYD7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

662476:KDQ40 RS09420
gene id: 662476:KDQ40_RS09420
uniprot id: M0JUH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

662476:KDQ40 RS17680
gene id: 662476:KDQ40_RS17680
uniprot id: M0JMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03250
gene id: 662476:KDQ40_RS03250
uniprot id: M0K8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

662476:KDQ40 RS13565
gene id: 662476:KDQ40_RS13565
uniprot id: M0K045
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

662476:KDQ40 RS02390
gene id: 662476:KDQ40_RS02390
uniprot id: M0K6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

662476:KDQ40 RS08130
gene id: 662476:KDQ40_RS08130
uniprot id: M0JV54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

662476:KDQ40 RS05835
gene id: 662476:KDQ40_RS05835
uniprot id: M0JX59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS11365
gene id: 662476:KDQ40_RS11365
uniprot id: M0JVU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

662476:KDQ40 RS21705
gene id: 662476:KDQ40_RS21705
uniprot id: M0JEQ2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

662476:KDQ40 RS07115
gene id: 662476:KDQ40_RS07115
uniprot id: M0K1N9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09385
gene id: 662476:KDQ40_RS09385
uniprot id: M0JYF0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

662476:KDQ40 RS19715
gene id: 662476:KDQ40_RS19715
uniprot id: M0JP41
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

662476:KDQ40 RS06625
gene id: 662476:KDQ40_RS06625
uniprot id: M0K0L5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09570
gene id: 662476:KDQ40_RS09570
uniprot id: M0JYI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

662476:KDQ40 RS03245
gene id: 662476:KDQ40_RS03245
uniprot id: M0K514
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09435
gene id: 662476:KDQ40_RS09435
uniprot id: M0JW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

662476:KDQ40 RS00245
gene id: 662476:KDQ40_RS00245
uniprot id: M0K534
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19860
gene id: 662476:KDQ40_RS19860
uniprot id: M0JPK3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

662476:KDQ40 RS10910
gene id: 662476:KDQ40_RS10910
uniprot id: M0JWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

662476:KDQ40 RS19485
gene id: 662476:KDQ40_RS19485
uniprot id: M0JSQ7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

662476:KDQ40 RS14460
gene id: 662476:KDQ40_RS14460
uniprot id: M0K0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

662476:KDQ40 RS14685
gene id: 662476:KDQ40_RS14685
uniprot id: M0JZR9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

662476:KDQ40 RS02740
gene id: 662476:KDQ40_RS02740
uniprot id: M0K8A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

662476:KDQ40 RS16930
gene id: 662476:KDQ40_RS16930
uniprot id: A0A8T8KIL5
names: Similarity
messages: Belongs to the leucine-binding protein family.

662476:KDQ40 RS11005
gene id: 662476:KDQ40_RS11005
uniprot id: M0JZC9
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

662476:KDQ40 RS14320
gene id: 662476:KDQ40_RS14320
uniprot id: M0K3N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

662476:KDQ40 RS13715
gene id: 662476:KDQ40_RS13715
uniprot id: M0K3W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

662476:KDQ40 RS07535
gene id: 662476:KDQ40_RS07535
uniprot id: M0JZD7
names: Similarity
messages: Belongs to the UPF0212 family.

662476:KDQ40 RS21995
gene id: 662476:KDQ40_RS21995
uniprot id: M0JC37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS15840
gene id: 662476:KDQ40_RS15840
uniprot id: M0K0S8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS17765
gene id: 662476:KDQ40_RS17765
uniprot id: M0JK84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03945
gene id: 662476:KDQ40_RS03945
uniprot id: M0K8K1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS16075
gene id: 662476:KDQ40_RS16075
uniprot id: M0JTJ9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

662476:KDQ40 RS15960
gene id: 662476:KDQ40_RS15960
uniprot id: M0K2G8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

662476:KDQ40 RS21310
gene id: 662476:KDQ40_RS21310
uniprot id: M0JE74
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS01720
gene id: 662476:KDQ40_RS01720
uniprot id: M0K7X6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

662476:KDQ40 RS01670
gene id: 662476:KDQ40_RS01670
uniprot id: M0K704
names: Similarity
messages: Belongs to the DtxR/MntR family.

662476:KDQ40 RS15225
gene id: 662476:KDQ40_RS15225
uniprot id: M0K5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

662476:KDQ40 RS03140
gene id: 662476:KDQ40_RS03140
uniprot id: M0K4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADH dehydrogenase family.
messages: Cytoplasm

662476:KDQ40 RS19560
gene id: 662476:KDQ40_RS19560
uniprot id: M0JSS1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS12230
gene id: 662476:KDQ40_RS12230
uniprot id: M0JV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS03035
gene id: 662476:KDQ40_RS03035
uniprot id: M0K6A1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS07290
gene id: 662476:KDQ40_RS07290
uniprot id: M0K0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02670
gene id: 662476:KDQ40_RS02670
uniprot id: M0K6H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS02645
gene id: 662476:KDQ40_RS02645
uniprot id: M0K6H8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

662476:KDQ40 RS07000
gene id: 662476:KDQ40_RS07000
uniprot id: M0JZ43
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

662476:KDQ40 RS06700
gene id: 662476:KDQ40_RS06700
uniprot id: M0K0M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

662476:KDQ40 RS06695
gene id: 662476:KDQ40_RS06695
uniprot id: M0JYZ0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06460
gene id: 662476:KDQ40_RS06460
uniprot id: M0K0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

662476:KDQ40 RS19615
gene id: 662476:KDQ40_RS19615
uniprot id: M0JP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS14490
gene id: 662476:KDQ40_RS14490
uniprot id: M0K4D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS09225
gene id: 662476:KDQ40_RS09225
uniprot id: M0JW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

662476:KDQ40 RS05855
gene id: 662476:KDQ40_RS05855
uniprot id: M0K127
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

662476:KDQ40 RS16195
gene id: 662476:KDQ40_RS16195
uniprot id: M0JUU2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

662476:KDQ40 RS04090
gene id: 662476:KDQ40_RS04090
uniprot id: M0K788
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

662476:KDQ40 RS15550
gene id: 662476:KDQ40_RS15550
uniprot id: M0K0X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

662476:KDQ40 RS03500
gene id: 662476:KDQ40_RS03500
uniprot id: M0K4X0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12550
gene id: 662476:KDQ40_RS12550
uniprot id: M0JYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

662476:KDQ40 RS07465
gene id: 662476:KDQ40_RS07465
uniprot id: M0K132
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09370
gene id: 662476:KDQ40_RS09370
uniprot id: M0JTZ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

662476:KDQ40 RS20635
gene id: 662476:KDQ40_RS20635
uniprot id: M0JRJ6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06130
gene id: 662476:KDQ40_RS06130
uniprot id: M0JYP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS17585
gene id: 662476:KDQ40_RS17585
uniprot id: M0JNN7
names: Similarity
messages: Belongs to the TFIIB family.

662476:KDQ40 RS08560
gene id: 662476:KDQ40_RS08560
uniprot id: M0JVC4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS16790
gene id: 662476:KDQ40_RS16790
uniprot id: M0JIS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS13470
gene id: 662476:KDQ40_RS13470
uniprot id: M0K400
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS01450
gene id: 662476:KDQ40_RS01450
uniprot id: M0K3R3
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

662476:KDQ40 RS06890
gene id: 662476:KDQ40_RS06890
uniprot id: M0K1J3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09885
gene id: 662476:KDQ40_RS09885
uniprot id: M0JUQ8
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

662476:KDQ40 RS02985
gene id: 662476:KDQ40_RS02985
uniprot id: M0K6B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS12540
gene id: 662476:KDQ40_RS12540
uniprot id: M0K074
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

662476:KDQ40 RS04470
gene id: 662476:KDQ40_RS04470
uniprot id: M0JZX4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19250
gene id: 662476:KDQ40_RS19250
uniprot id: M0JQM0
names: Similarity
messages: Belongs to the GbsR family.

662476:KDQ40 RS01425
gene id: 662476:KDQ40_RS01425
uniprot id: M0K3R9
names: Similarity
messages: Belongs to the TrpC family.

662476:KDQ40 RS01440
gene id: 662476:KDQ40_RS01440
uniprot id: M0K6H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

662476:KDQ40 RS07585
gene id: 662476:KDQ40_RS07585
uniprot id: M0JZ79
names: Similarity
messages: Belongs to the arginase family.

662476:KDQ40 RS11980
gene id: 662476:KDQ40_RS11980
uniprot id: M0JX23
names: Similarity
messages: Belongs to the HMBS family.

662476:KDQ40 RS12950
gene id: 662476:KDQ40_RS12950
uniprot id: M0K3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

662476:KDQ40 RS06975
gene id: 662476:KDQ40_RS06975
uniprot id: M0JZ39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS15850
gene id: 662476:KDQ40_RS15850
uniprot id: M0K5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS19445
gene id: 662476:KDQ40_RS19445
uniprot id: A0A8T8KTB2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

662476:KDQ40 RS05375
gene id: 662476:KDQ40_RS05375
uniprot id: M0JZV2
names: Similarity
messages: Belongs to the Nth/MutY family.

662476:KDQ40 RS10785
gene id: 662476:KDQ40_RS10785
uniprot id: M0JY45
names: Similarity
messages: Belongs to the Ahb/Nir family.

662476:KDQ40 RS03460
gene id: 662476:KDQ40_RS03460
uniprot id: M0K7X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

662476:KDQ40 RS12030
gene id: 662476:KDQ40_RS12030
uniprot id: M0JX33
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS09035
gene id: 662476:KDQ40_RS09035
uniprot id: M0JUA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS15530
gene id: 662476:KDQ40_RS15530
uniprot id: M0K1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

662476:KDQ40 RS16940
gene id: 662476:KDQ40_RS16940
uniprot id: M0JIP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03050
gene id: 662476:KDQ40_RS03050
uniprot id: M0K929
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

662476:KDQ40 RS08100
gene id: 662476:KDQ40_RS08100
uniprot id: M0JVN7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

662476:KDQ40 RS16690
gene id: 662476:KDQ40_RS16690
uniprot id: M0JMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

662476:KDQ40 RS16545
gene id: 662476:KDQ40_RS16545
uniprot id: M0JLU4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS11780
gene id: 662476:KDQ40_RS11780
uniprot id: M0JSM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12675
gene id: 662476:KDQ40_RS12675
uniprot id: M0JZU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

662476:KDQ40 RS02910
gene id: 662476:KDQ40_RS02910
uniprot id: M0K4P1
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS06140
gene id: 662476:KDQ40_RS06140
uniprot id: M0K165
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09830
gene id: 662476:KDQ40_RS09830
uniprot id: M0JUP8
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

662476:KDQ40 RS15590
gene id: 662476:KDQ40_RS15590
uniprot id: M0K5H0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

662476:KDQ40 RS15255
gene id: 662476:KDQ40_RS15255
uniprot id: M0K4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

662476:KDQ40 RS05250
gene id: 662476:KDQ40_RS05250
uniprot id: M0JZR6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06725
gene id: 662476:KDQ40_RS06725
uniprot id: M0K0N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

662476:KDQ40 RS16540
gene id: 662476:KDQ40_RS16540
uniprot id: M0JMQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS00225
gene id: 662476:KDQ40_RS00225
uniprot id: M0K1G0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

662476:KDQ40 RS04810
gene id: 662476:KDQ40_RS04810
uniprot id: M0K194
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS11975
gene id: 662476:KDQ40_RS11975
uniprot id: M0JW57
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

662476:KDQ40 RS19580
gene id: 662476:KDQ40_RS19580
uniprot id: M0JRX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS00845
gene id: 662476:KDQ40_RS00845
uniprot id: M0K448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

662476:KDQ40 RS04325
gene id: 662476:KDQ40_RS04325
uniprot id: M0K1P9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

662476:KDQ40 RS10610
gene id: 662476:KDQ40_RS10610
uniprot id: M0JZ53
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

662476:KDQ40 RS23095
gene id: 662476:KDQ40_RS23095
uniprot id: M0JP03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS14065
gene id: 662476:KDQ40_RS14065
uniprot id: M0K4M2
names: Similarity
messages: Belongs to the P(II) protein family.

662476:KDQ40 RS18430
gene id: 662476:KDQ40_RS18430
uniprot id: M0JG45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS11650
gene id: 662476:KDQ40_RS11650
uniprot id: M0JT23
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

662476:KDQ40 RS08485
gene id: 662476:KDQ40_RS08485
uniprot id: M0JXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

662476:KDQ40 RS07390
gene id: 662476:KDQ40_RS07390
uniprot id: M0JZA9
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

662476:KDQ40 RS13100
gene id: 662476:KDQ40_RS13100
uniprot id: M0K2M5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

662476:KDQ40 RS11835
gene id: 662476:KDQ40_RS11835
uniprot id: M0JUW0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

662476:KDQ40 RS13180
gene id: 662476:KDQ40_RS13180
uniprot id: M0K0R4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

662476:KDQ40 RS12085
gene id: 662476:KDQ40_RS12085
uniprot id: M0JTA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

662476:KDQ40 RS10900
gene id: 662476:KDQ40_RS10900
uniprot id: M0JVA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

662476:KDQ40 RS09075
gene id: 662476:KDQ40_RS09075
uniprot id: M0JYA7
names: Similarity
messages: Belongs to the TPP enzyme family.

662476:KDQ40 RS22735
gene id: 662476:KDQ40_RS22735
uniprot id: M0JPZ9
names: Similarity
messages: Belongs to the TFIIB family.

662476:KDQ40 RS12640
gene id: 662476:KDQ40_RS12640
uniprot id: M0K053
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

662476:KDQ40 RS02660
gene id: 662476:KDQ40_RS02660
uniprot id: M0K9A5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

662476:KDQ40 RS04570
gene id: 662476:KDQ40_RS04570
uniprot id: M0JZY9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

662476:KDQ40 RS11630
gene id: 662476:KDQ40_RS11630
uniprot id: M0JSJ7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

662476:KDQ40 RS10905
gene id: 662476:KDQ40_RS10905
uniprot id: M0JUS7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS20345
gene id: 662476:KDQ40_RS20345
uniprot id: M0JQ64
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS18865
gene id: 662476:KDQ40_RS18865
uniprot id: M0JL43
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS02685
gene id: 662476:KDQ40_RS02685
uniprot id: M0K9A0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

662476:KDQ40 RS19910
gene id: 662476:KDQ40_RS19910
uniprot id: M0JPL1
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS06015
gene id: 662476:KDQ40_RS06015
uniprot id: M0K149
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS03590
gene id: 662476:KDQ40_RS03590
uniprot id: M0K7V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662476:KDQ40 RS01350
gene id: 662476:KDQ40_RS01350
uniprot id: M0K3T4
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

662476:KDQ40 RS03355
gene id: 662476:KDQ40_RS03355
uniprot id: M0K7Z2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS09620
gene id: 662476:KDQ40_RS09620
uniprot id: M0JYJ5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS02650
gene id: 662476:KDQ40_RS02650
uniprot id: M0K4V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

662476:KDQ40 RS12070
gene id: 662476:KDQ40_RS12070
uniprot id: M0JV02
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

662476:KDQ40 RS07970
gene id: 662476:KDQ40_RS07970
uniprot id: M0JVL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

662476:KDQ40 RS12670
gene id: 662476:KDQ40_RS12670
uniprot id: A0A8T8KB62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662476:KDQ40 RS08870
gene id: 662476:KDQ40_RS08870
uniprot id: M0JZ09
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

662476:KDQ40 RS07930
gene id: 662476:KDQ40_RS07930
uniprot id: M0JV14
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

662476:KDQ40 RS10605
gene id: 662476:KDQ40_RS10605
uniprot id: M0JY07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

662476:KDQ40 RS11805
gene id: 662476:KDQ40_RS11805
uniprot id: M0JSM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS11660
gene id: 662476:KDQ40_RS11660
uniprot id: M0JUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

662476:KDQ40 RS02010
gene id: 662476:KDQ40_RS02010
uniprot id: M0K7Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

662476:KDQ40 RS00205
gene id: 662476:KDQ40_RS00205
uniprot id: M0K234
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS16515
gene id: 662476:KDQ40_RS16515
uniprot id: M0JSA4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

662476:KDQ40 RS02695
gene id: 662476:KDQ40_RS02695
uniprot id: M0K6G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS20630
gene id: 662476:KDQ40_RS20630
uniprot id: A0A8T8KHV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12880
gene id: 662476:KDQ40_RS12880
uniprot id: M0K2S7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS15625
gene id: 662476:KDQ40_RS15625
uniprot id: M0K5G6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

662476:KDQ40 RS00060
gene id: 662476:KDQ40_RS00060
uniprot id: M0K358
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS01480
gene id: 662476:KDQ40_RS01480
uniprot id: M0K7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

662476:KDQ40 RS19350
gene id: 662476:KDQ40_RS19350
uniprot id: M0JQN6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS19565
gene id: 662476:KDQ40_RS19565
uniprot id: M0JP10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS18625
gene id: 662476:KDQ40_RS18625
uniprot id: M0JIG6
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

662476:KDQ40 RS23110
gene id: 662476:KDQ40_RS23110
uniprot id: M0JP85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS11455
gene id: 662476:KDQ40_RS11455
uniprot id: M0JSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS02300
gene id: 662476:KDQ40_RS02300
uniprot id: M0K2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

662476:KDQ40 RS02600
gene id: 662476:KDQ40_RS02600
uniprot id: M0K5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

662476:KDQ40 RS02585
gene id: 662476:KDQ40_RS02585
uniprot id: M0K8E5
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

662476:KDQ40 RS17015
gene id: 662476:KDQ40_RS17015
uniprot id: M0JIM5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19675
gene id: 662476:KDQ40_RS19675
uniprot id: M0JQT7
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Tetramer of two components I and two components II.

662476:KDQ40 RS17780
gene id: 662476:KDQ40_RS17780
uniprot id: M0JPD7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS16165
gene id: 662476:KDQ40_RS16165
uniprot id: A0A8T8KH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

662476:KDQ40 RS14845
gene id: 662476:KDQ40_RS14845
uniprot id: M0K322
names: Similarity
messages: Belongs to the HsdR family.

662476:KDQ40 RS07420
gene id: 662476:KDQ40_RS07420
uniprot id: M0K121
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS00535
gene id: 662476:KDQ40_RS00535
uniprot id: M0K638
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS18985
gene id: 662476:KDQ40_RS18985
uniprot id: M0JK76
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS09780
gene id: 662476:KDQ40_RS09780
uniprot id: M0JUN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS16635
gene id: 662476:KDQ40_RS16635
uniprot id: M0JIV0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS06715
gene id: 662476:KDQ40_RS06715
uniprot id: M0JX02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS04915
gene id: 662476:KDQ40_RS04915
uniprot id: M0K1B6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

662476:KDQ40 RS08565
gene id: 662476:KDQ40_RS08565
uniprot id: M0JXH7
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS13695
gene id: 662476:KDQ40_RS13695
uniprot id: M0K355
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

662476:KDQ40 RS07560
gene id: 662476:KDQ40_RS07560
uniprot id: M0JZE0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

662476:KDQ40 RS09380
gene id: 662476:KDQ40_RS09380
uniprot id: M0JXA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS13810
gene id: 662476:KDQ40_RS13810
uniprot id: M0JZF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

662476:KDQ40 RS16870
gene id: 662476:KDQ40_RS16870
uniprot id: M0JMI3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

662476:KDQ40 RS04420
gene id: 662476:KDQ40_RS04420
uniprot id: M0JZW8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS14965
gene id: 662476:KDQ40_RS14965
uniprot id: M0K5S0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS11870
gene id: 662476:KDQ40_RS11870
uniprot id: M0JX04
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS16320
gene id: 662476:KDQ40_RS16320
uniprot id: M0JTE4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS06990
gene id: 662476:KDQ40_RS06990
uniprot id: M0JXQ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

662476:KDQ40 RS15865
gene id: 662476:KDQ40_RS15865
uniprot id: M0K0S3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS04595
gene id: 662476:KDQ40_RS04595
uniprot id: M0JZZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS02110
gene id: 662476:KDQ40_RS02110
uniprot id: M0K6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

662476:KDQ40 RS15150
gene id: 662476:KDQ40_RS15150
uniprot id: M0K5P0
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS03295
gene id: 662476:KDQ40_RS03295
uniprot id: M0K506
names: Similarity
messages: Belongs to the complex I subunit 3 family.

662476:KDQ40 RS16175
gene id: 662476:KDQ40_RS16175
uniprot id: M0JTP1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS11640
gene id: 662476:KDQ40_RS11640
uniprot id: M0JVZ6
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

662476:KDQ40 RS09515
gene id: 662476:KDQ40_RS09515
uniprot id: M0JXD0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19290
gene id: 662476:KDQ40_RS19290
uniprot id: M0JNV3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS14300
gene id: 662476:KDQ40_RS14300
uniprot id: M0K1T1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662476:KDQ40 RS09160
gene id: 662476:KDQ40_RS09160
uniprot id: M0JUC6
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

662476:KDQ40 RS04880
gene id: 662476:KDQ40_RS04880
uniprot id: M0JZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS13780
gene id: 662476:KDQ40_RS13780
uniprot id: M0K178
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS01315
gene id: 662476:KDQ40_RS01315
uniprot id: M0K6K4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

662476:KDQ40 RS07600
gene id: 662476:KDQ40_RS07600
uniprot id: M0JVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

662476:KDQ40 RS08365
gene id: 662476:KDQ40_RS08365
uniprot id: M0JYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS07920
gene id: 662476:KDQ40_RS07920
uniprot id: M0JZJ5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

662476:KDQ40 RS13800
gene id: 662476:KDQ40_RS13800
uniprot id: M0K334
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS17915
gene id: 662476:KDQ40_RS17915
uniprot id: M0JPH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09720
gene id: 662476:KDQ40_RS09720
uniprot id: M0JXG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

662476:KDQ40 RS13915
gene id: 662476:KDQ40_RS13915
uniprot id: M0K3V8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07840
gene id: 662476:KDQ40_RS07840
uniprot id: M0K0B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

662476:KDQ40 RS12585
gene id: 662476:KDQ40_RS12585
uniprot id: M0K216
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

662476:KDQ40 RS03695
gene id: 662476:KDQ40_RS03695
uniprot id: M0K5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

662476:KDQ40 RS11770
gene id: 662476:KDQ40_RS11770
uniprot id: M0JWY9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07750
gene id: 662476:KDQ40_RS07750
uniprot id: M0JVR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS13365
gene id: 662476:KDQ40_RS13365
uniprot id: M0K416
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08310
gene id: 662476:KDQ40_RS08310
uniprot id: M0JXD8
names: Similarity
messages: Belongs to the peptidase S1C family.

662476:KDQ40 RS04045
gene id: 662476:KDQ40_RS04045
uniprot id: M0K7T3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

662476:KDQ40 RS19340
gene id: 662476:KDQ40_RS19340
uniprot id: M0JNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS15520
gene id: 662476:KDQ40_RS15520
uniprot id: M0K2R6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08940
gene id: 662476:KDQ40_RS08940
uniprot id: M0JXN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS09755
gene id: 662476:KDQ40_RS09755
uniprot id: M0JUM9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS08425
gene id: 662476:KDQ40_RS08425
uniprot id: M0JVT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

662476:KDQ40 RS00095
gene id: 662476:KDQ40_RS00095
uniprot id: M0K1Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS05430
gene id: 662476:KDQ40_RS05430
uniprot id: M0K0S4
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

662476:KDQ40 RS08800
gene id: 662476:KDQ40_RS08800
uniprot id: M0JZY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

662476:KDQ40 RS19670
gene id: 662476:KDQ40_RS19670
uniprot id: M0JNM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

662476:KDQ40 RS13675
gene id: 662476:KDQ40_RS13675
uniprot id: M0K357
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS14020
gene id: 662476:KDQ40_RS14020
uniprot id: M0K3T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS12520
gene id: 662476:KDQ40_RS12520
uniprot id: M0JYE5
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

662476:KDQ40 RS02350
gene id: 662476:KDQ40_RS02350
uniprot id: M0K2X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS20140
gene id: 662476:KDQ40_RS20140
uniprot id: M0JT14
names: Caution
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS11285
gene id: 662476:KDQ40_RS11285
uniprot id: M0JVT8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS06910
gene id: 662476:KDQ40_RS06910
uniprot id: M0K0R2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS10255
gene id: 662476:KDQ40_RS10255
uniprot id: M0JXT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

662476:KDQ40 RS01790
gene id: 662476:KDQ40_RS01790
uniprot id: M0K3Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS15745
gene id: 662476:KDQ40_RS15745
uniprot id: M0K1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

662476:KDQ40 RS09330
gene id: 662476:KDQ40_RS09330
uniprot id: M0JX96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

662476:KDQ40 RS10980
gene id: 662476:KDQ40_RS10980
uniprot id: M0JVC5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS18845
gene id: 662476:KDQ40_RS18845
uniprot id: M0JL29
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07330
gene id: 662476:KDQ40_RS07330
uniprot id: M0JXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

662476:KDQ40 RS20005
gene id: 662476:KDQ40_RS20005
uniprot id: M0JQ05
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

662476:KDQ40 RS13290
gene id: 662476:KDQ40_RS13290
uniprot id: M0JZD5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

662476:KDQ40 RS17030
gene id: 662476:KDQ40_RS17030
uniprot id: M0JKI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03220
gene id: 662476:KDQ40_RS03220
uniprot id: M0K8Z3
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS06960
gene id: 662476:KDQ40_RS06960
uniprot id: M0K1K7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS11480
gene id: 662476:KDQ40_RS11480
uniprot id: M0JSH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

662476:KDQ40 RS03215
gene id: 662476:KDQ40_RS03215
uniprot id: M0K519
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02965
gene id: 662476:KDQ40_RS02965
uniprot id: M0K561
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08890
gene id: 662476:KDQ40_RS08890
uniprot id: M0JXM3
names: Similarity
messages: Belongs to the peptidase S9C family.

662476:KDQ40 RS09300
gene id: 662476:KDQ40_RS09300
uniprot id: M0JW48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

662476:KDQ40 RS09405
gene id: 662476:KDQ40_RS09405
uniprot id: M0JW64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS08205
gene id: 662476:KDQ40_RS08205
uniprot id: M0JV64
names: Subcellular Location Annotation
messages: Cell membrane

662476:KDQ40 RS12695
gene id: 662476:KDQ40_RS12695
uniprot id: M0JZ95
names: Similarity
messages: Belongs to the UPF0215 family.

662476:KDQ40 RS10920
gene id: 662476:KDQ40_RS10920
uniprot id: M0JZB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

662476:KDQ40 RS11490
gene id: 662476:KDQ40_RS11490
uniprot id: M0JVX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS02120
gene id: 662476:KDQ40_RS02120
uniprot id: M0K316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

662476:KDQ40 RS14040
gene id: 662476:KDQ40_RS14040
uniprot id: M0K4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

662476:KDQ40 RS01920
gene id: 662476:KDQ40_RS01920
uniprot id: M0K6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662476:KDQ40 RS21200
gene id: 662476:KDQ40_RS21200
uniprot id: A0A8T8KIH1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

662476:KDQ40 RS04770
gene id: 662476:KDQ40_RS04770
uniprot id: M0JY97
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS08910
gene id: 662476:KDQ40_RS08910
uniprot id: M0JVI3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

662476:KDQ40 RS13820
gene id: 662476:KDQ40_RS13820
uniprot id: M0K3U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS13450
gene id: 662476:KDQ40_RS13450
uniprot id: M0K1C8
names: Subcellular Location Annotation
messages: Nucleus

662476:KDQ40 RS13885
gene id: 662476:KDQ40_RS13885
uniprot id: M0K3W3
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

662476:KDQ40 RS05830
gene id: 662476:KDQ40_RS05830
uniprot id: M0K123
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS20010
gene id: 662476:KDQ40_RS20010
uniprot id: M0JPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

662476:KDQ40 RS12725
gene id: 662476:KDQ40_RS12725
uniprot id: M0JZS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS05680
gene id: 662476:KDQ40_RS05680
uniprot id: M0K0Z8
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS15285
gene id: 662476:KDQ40_RS15285
uniprot id: M0K4Q4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

662476:KDQ40 RS14030
gene id: 662476:KDQ40_RS14030
uniprot id: M0K036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

662476:KDQ40 RS13335
gene id: 662476:KDQ40_RS13335
uniprot id: M0K085
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

662476:KDQ40 RS03930
gene id: 662476:KDQ40_RS03930
uniprot id: M0K5R6
names: Similarity
messages: Belongs to the AOR/FOR family.

662476:KDQ40 RS03675
gene id: 662476:KDQ40_RS03675
uniprot id: M0K470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

662476:KDQ40 RS07205
gene id: 662476:KDQ40_RS07205
uniprot id: M0JXA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

662476:KDQ40 RS15385
gene id: 662476:KDQ40_RS15385
uniprot id: M0K4N8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

662476:KDQ40 RS05060
gene id: 662476:KDQ40_RS05060
uniprot id: M0JY92
names: Similarity
messages: Belongs to the UPF0179 family.

662476:KDQ40 RS01890
gene id: 662476:KDQ40_RS01890
uniprot id: M0K3W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS05495
gene id: 662476:KDQ40_RS05495
uniprot id: M0JYC0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

662476:KDQ40 RS19690
gene id: 662476:KDQ40_RS19690
uniprot id: M0QT90
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS22090
gene id: 662476:KDQ40_RS22090
uniprot id: A0A8T8KI87
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10975
gene id: 662476:KDQ40_RS10975
uniprot id: M0JZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS02655
gene id: 662476:KDQ40_RS02655
uniprot id: M0K5C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS14500
gene id: 662476:KDQ40_RS14500
uniprot id: M0K1P1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662476:KDQ40 RS12610
gene id: 662476:KDQ40_RS12610
uniprot id: M0K214
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

662476:KDQ40 RS15630
gene id: 662476:KDQ40_RS15630
uniprot id: A0A8T8KKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

662476:KDQ40 RS22650
gene id: 662476:KDQ40_RS22650
uniprot id: M0JQY0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS08720
gene id: 662476:KDQ40_RS08720
uniprot id: M0JYX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

662476:KDQ40 RS01040
gene id: 662476:KDQ40_RS01040
uniprot id: M0K6R4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

662476:KDQ40 RS15725
gene id: 662476:KDQ40_RS15725
uniprot id: M0K5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

662476:KDQ40 RS11645
gene id: 662476:KDQ40_RS11645
uniprot id: M0JWW9
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

662476:KDQ40 RS15525
gene id: 662476:KDQ40_RS15525
uniprot id: M0K0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

662476:KDQ40 RS08695
gene id: 662476:KDQ40_RS08695
uniprot id: A0A8T8KA98
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

662476:KDQ40 RS19930
gene id: 662476:KDQ40_RS19930
uniprot id: M0JPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662476:KDQ40 RS02575
gene id: 662476:KDQ40_RS02575
uniprot id: M0K5E0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

662476:KDQ40 RS06115
gene id: 662476:KDQ40_RS06115
uniprot id: M0K162
names: Similarity
messages: Belongs to the DNA photolyase family.

662476:KDQ40 RS15415
gene id: 662476:KDQ40_RS15415
uniprot id: M0K2S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS11795
gene id: 662476:KDQ40_RS11795
uniprot id: M0JWZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

662476:KDQ40 RS04070
gene id: 662476:KDQ40_RS04070
uniprot id: M0K7S9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

662476:KDQ40 RS05845
gene id: 662476:KDQ40_RS05845
uniprot id: M0JYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

662476:KDQ40 RS21235
gene id: 662476:KDQ40_RS21235
uniprot id: M0JHX6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

662476:KDQ40 RS07935
gene id: 662476:KDQ40_RS07935
uniprot id: M0JX72
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

662476:KDQ40 RS21315
gene id: 662476:KDQ40_RS21315
uniprot id: M0JHW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14375
gene id: 662476:KDQ40_RS14375
uniprot id: M0K1R5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

662476:KDQ40 RS11510
gene id: 662476:KDQ40_RS11510
uniprot id: M0JUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

662476:KDQ40 RS18010
gene id: 662476:KDQ40_RS18010
uniprot id: M0JMP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS12185
gene id: 662476:KDQ40_RS12185
uniprot id: M0JX68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

662476:KDQ40 RS16595
gene id: 662476:KDQ40_RS16595
uniprot id: M0JLT3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

662476:KDQ40 RS04565
gene id: 662476:KDQ40_RS04565
uniprot id: M0JY66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

662476:KDQ40 RS17550
gene id: 662476:KDQ40_RS17550
uniprot id: M0JJJ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS04290
gene id: 662476:KDQ40_RS04290
uniprot id: M0JY27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

662476:KDQ40 RS01900
gene id: 662476:KDQ40_RS01900
uniprot id: M0K6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

662476:KDQ40 RS03300
gene id: 662476:KDQ40_RS03300
uniprot id: M0K8X7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

662476:KDQ40 RS02180
gene id: 662476:KDQ40_RS02180
uniprot id: M0K7M0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS14570
gene id: 662476:KDQ40_RS14570
uniprot id: M0K3J3
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS05600
gene id: 662476:KDQ40_RS05600
uniprot id: M0K018
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

662476:KDQ40 RS01210
gene id: 662476:KDQ40_RS01210
uniprot id: M0K2Q5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS21190
gene id: 662476:KDQ40_RS21190
uniprot id: M0JG77
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS20595
gene id: 662476:KDQ40_RS20595
uniprot id: M0JNN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

662476:KDQ40 RS00570
gene id: 662476:KDQ40_RS00570
uniprot id: M0K2F2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

662476:KDQ40 RS12840
gene id: 662476:KDQ40_RS12840
uniprot id: M0JZ64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

662476:KDQ40 RS15750
gene id: 662476:KDQ40_RS15750
uniprot id: M0K5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

662476:KDQ40 RS07145
gene id: 662476:KDQ40_RS07145
uniprot id: M0K1P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS06455
gene id: 662476:KDQ40_RS06455
uniprot id: M0JWV8
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS06800
gene id: 662476:KDQ40_RS06800
uniprot id: M0JZ07
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS00380
gene id: 662476:KDQ40_RS00380
uniprot id: M0K728
names: Similarity
messages: Belongs to the UPF0146 family.

662476:KDQ40 RS14630
gene id: 662476:KDQ40_RS14630
uniprot id: M0JZS6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS02435
gene id: 662476:KDQ40_RS02435
uniprot id: M0K7G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

662476:KDQ40 RS00560
gene id: 662476:KDQ40_RS00560
uniprot id: M0K633
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12745
gene id: 662476:KDQ40_RS12745
uniprot id: M0JZ85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

662476:KDQ40 RS20020
gene id: 662476:KDQ40_RS20020
uniprot id: M0JSZ4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10185
gene id: 662476:KDQ40_RS10185
uniprot id: M0JYW5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

662476:KDQ40 RS05660
gene id: 662476:KDQ40_RS05660
uniprot id: M0JX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS02255
gene id: 662476:KDQ40_RS02255
uniprot id: M0K3N7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

662476:KDQ40 RS13805
gene id: 662476:KDQ40_RS13805
uniprot id: M0K173
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS12285
gene id: 662476:KDQ40_RS12285
uniprot id: M0JWB2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

662476:KDQ40 RS03080
gene id: 662476:KDQ40_RS03080
uniprot id: M0K838
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

662476:KDQ40 RS02715
gene id: 662476:KDQ40_RS02715
uniprot id: M0K8B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS07555
gene id: 662476:KDQ40_RS07555
uniprot id: A0A8T8KH01
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662476:KDQ40 RS07140
gene id: 662476:KDQ40_RS07140
uniprot id: M0K0V9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13025
gene id: 662476:KDQ40_RS13025
uniprot id: M0K2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS06145
gene id: 662476:KDQ40_RS06145
uniprot id: A0A8T8KDW4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19685
gene id: 662476:KDQ40_RS19685
uniprot id: M0JSU3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15610
gene id: 662476:KDQ40_RS15610
uniprot id: M0K2Q4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS01310
gene id: 662476:KDQ40_RS01310
uniprot id: M0K2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

662476:KDQ40 RS09545
gene id: 662476:KDQ40_RS09545
uniprot id: M0JYH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

662476:KDQ40 RS20400
gene id: 662476:KDQ40_RS20400
uniprot id: M0JPT8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02720
gene id: 662476:KDQ40_RS02720
uniprot id: A0A8T8KFB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

662476:KDQ40 RS08840
gene id: 662476:KDQ40_RS08840
uniprot id: M0JXL4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS18590
gene id: 662476:KDQ40_RS18590
uniprot id: M0JKD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

662476:KDQ40 RS17535
gene id: 662476:KDQ40_RS17535
uniprot id: M0JNP9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

662476:KDQ40 RS08140
gene id: 662476:KDQ40_RS08140
uniprot id: M0JYM3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS03455
gene id: 662476:KDQ40_RS03455
uniprot id: M0K8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

662476:KDQ40 RS09415
gene id: 662476:KDQ40_RS09415
uniprot id: M0JYF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

662476:KDQ40 RS05605
gene id: 662476:KDQ40_RS05605
uniprot id: M0K0X8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

662476:KDQ40 RS04980
gene id: 662476:KDQ40_RS04980
uniprot id: M0JY72
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS05655
gene id: 662476:KDQ40_RS05655
uniprot id: M0K0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS15155
gene id: 662476:KDQ40_RS15155
uniprot id: M0K4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS08615
gene id: 662476:KDQ40_RS08615
uniprot id: M0JXI3
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

662476:KDQ40 RS07080
gene id: 662476:KDQ40_RS07080
uniprot id: M0K0U7
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

662476:KDQ40 RS03280
gene id: 662476:KDQ40_RS03280
uniprot id: M0K804
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15410
gene id: 662476:KDQ40_RS15410
uniprot id: M0K4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS14650
gene id: 662476:KDQ40_RS14650
uniprot id: M0K1L4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

662476:KDQ40 RS00630
gene id: 662476:KDQ40_RS00630
uniprot id: M0K6Y5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS02455
gene id: 662476:KDQ40_RS02455
uniprot id: M0K3K0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

662476:KDQ40 RS15940
gene id: 662476:KDQ40_RS15940
uniprot id: M0K0N9
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

662476:KDQ40 RS10080
gene id: 662476:KDQ40_RS10080
uniprot id: M0JXP4
names: Similarity
messages: Belongs to the PspA/IM30 family.

662476:KDQ40 RS17760
gene id: 662476:KDQ40_RS17760
uniprot id: M0JMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS12905
gene id: 662476:KDQ40_RS12905
uniprot id: M0K2S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

662476:KDQ40 RS20130
gene id: 662476:KDQ40_RS20130
uniprot id: M0JQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS16565
gene id: 662476:KDQ40_RS16565
uniprot id: M0JMQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08060
gene id: 662476:KDQ40_RS08060
uniprot id: M0JX99
names: Subcellular Location Annotation
messages: Cell membrane

662476:KDQ40 RS10695
gene id: 662476:KDQ40_RS10695
uniprot id: M0JV60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

662476:KDQ40 RS19185
gene id: 662476:KDQ40_RS19185
uniprot id: M0JNT4
names: Similarity
messages: Belongs to the SCO1/2 family.

662476:KDQ40 RS21945
gene id: 662476:KDQ40_RS21945
uniprot id: M0JC45
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS00965
gene id: 662476:KDQ40_RS00965
uniprot id: M0K6S7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS04175
gene id: 662476:KDQ40_RS04175
uniprot id: M0KAP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS04885
gene id: 662476:KDQ40_RS04885
uniprot id: M0K1B2
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

662476:KDQ40 RS10950
gene id: 662476:KDQ40_RS10950
uniprot id: M0JZB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS03225
gene id: 662476:KDQ40_RS03225
uniprot id: M0K811
names: Similarity
messages: Belongs to the pirin family.

662476:KDQ40 RS06670
gene id: 662476:KDQ40_RS06670
uniprot id: M0JYY6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS07515
gene id: 662476:KDQ40_RS07515
uniprot id: M0K142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS01940
gene id: 662476:KDQ40_RS01940
uniprot id: M0K7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

662476:KDQ40 RS00080
gene id: 662476:KDQ40_RS00080
uniprot id: M0K503
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS19415
gene id: 662476:KDQ40_RS19415
uniprot id: M0JNX9
names: Subcellular Location Annotation
messages: Nucleus

662476:KDQ40 RS13495
gene id: 662476:KDQ40_RS13495
uniprot id: M0K3Z6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS20605
gene id: 662476:KDQ40_RS20605
uniprot id: M0JQF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

662476:KDQ40 RS15120
gene id: 662476:KDQ40_RS15120
uniprot id: M0K4S6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

662476:KDQ40 RS05920
gene id: 662476:KDQ40_RS05920
uniprot id: M0JWL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS20580
gene id: 662476:KDQ40_RS20580
uniprot id: M0JQF4
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS04600
gene id: 662476:KDQ40_RS04600
uniprot id: M0K1U7
names: Similarity
messages: Belongs to the acylphosphatase family.

662476:KDQ40 RS06395
gene id: 662476:KDQ40_RS06395
uniprot id: M0K1A5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS14200
gene id: 662476:KDQ40_RS14200
uniprot id: M0K1V0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS16700
gene id: 662476:KDQ40_RS16700
uniprot id: M0JKQ3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13940
gene id: 662476:KDQ40_RS13940
uniprot id: A0A8T8KLH6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS03485
gene id: 662476:KDQ40_RS03485
uniprot id: M0K7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS20540
gene id: 662476:KDQ40_RS20540
uniprot id: M0JU33
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS06350
gene id: 662476:KDQ40_RS06350
uniprot id: M0JXE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS01830
gene id: 662476:KDQ40_RS01830
uniprot id: M0K513
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

662476:KDQ40 RS14325
gene id: 662476:KDQ40_RS14325
uniprot id: M0K1S4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

662476:KDQ40 RS01800
gene id: 662476:KDQ40_RS01800
uniprot id: M0K6X4
names: Similarity
messages: Belongs to the group II decarboxylase family.

662476:KDQ40 RS19710
gene id: 662476:KDQ40_RS19710
uniprot id: M0JSU9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

662476:KDQ40 RS19505
gene id: 662476:KDQ40_RS19505
uniprot id: M0JRW0
names: Similarity
messages: Belongs to the GcvT family.

662476:KDQ40 RS11375
gene id: 662476:KDQ40_RS11375
uniprot id: M0JSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

662476:KDQ40 RS07590
gene id: 662476:KDQ40_RS07590
uniprot id: M0K059
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

662476:KDQ40 RS01465
gene id: 662476:KDQ40_RS01465
uniprot id: M0K6H5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

662476:KDQ40 RS01460
gene id: 662476:KDQ40_RS01460
uniprot id: M0K2J7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS15160
gene id: 662476:KDQ40_RS15160
uniprot id: M0K2W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS09775
gene id: 662476:KDQ40_RS09775
uniprot id: M0JYM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14735
gene id: 662476:KDQ40_RS14735
uniprot id: M0K106
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS03495
gene id: 662476:KDQ40_RS03495
uniprot id: M0K4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS00905
gene id: 662476:KDQ40_RS00905
uniprot id: M0K2A8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS06900
gene id: 662476:KDQ40_RS06900
uniprot id: M0JX36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS08270
gene id: 662476:KDQ40_RS08270
uniprot id: M0JZQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

662476:KDQ40 RS19305
gene id: 662476:KDQ40_RS19305
uniprot id: M0JRS0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS13900
gene id: 662476:KDQ40_RS13900
uniprot id: M0K066
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

662476:KDQ40 RS09315
gene id: 662476:KDQ40_RS09315
uniprot id: M0JUF8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

662476:KDQ40 RS03395
gene id: 662476:KDQ40_RS03395
uniprot id: M0K4Y8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS15620
gene id: 662476:KDQ40_RS15620
uniprot id: M0K1H8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS03745
gene id: 662476:KDQ40_RS03745
uniprot id: M0K5V2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS10480
gene id: 662476:KDQ40_RS10480
uniprot id: M0JXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662476:KDQ40 RS14005
gene id: 662476:KDQ40_RS14005
uniprot id: M0K043
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS00105
gene id: 662476:KDQ40_RS00105
uniprot id: M0K4Z8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

662476:KDQ40 RS14610
gene id: 662476:KDQ40_RS14610
uniprot id: M0JZT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

662476:KDQ40 RS14520
gene id: 662476:KDQ40_RS14520
uniprot id: M0K3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

662476:KDQ40 RS04235
gene id: 662476:KDQ40_RS04235
uniprot id: M0K764
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06855
gene id: 662476:KDQ40_RS06855
uniprot id: M0JZ17
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

662476:KDQ40 RS12050
gene id: 662476:KDQ40_RS12050
uniprot id: A0A8T8KES5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02075
gene id: 662476:KDQ40_RS02075
uniprot id: M0K3S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

662476:KDQ40 RS08920
gene id: 662476:KDQ40_RS08920
uniprot id: M0JZ19
names: Similarity
messages: Belongs to the band 7/mec-2 family.

662476:KDQ40 RS00440
gene id: 662476:KDQ40_RS00440
uniprot id: M0K4A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

662476:KDQ40 RS18085
gene id: 662476:KDQ40_RS18085
uniprot id: A0A8T8KQW0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS03310
gene id: 662476:KDQ40_RS03310
uniprot id: M0K645
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06760
gene id: 662476:KDQ40_RS06760
uniprot id: M0K1G8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS08520
gene id: 662476:KDQ40_RS08520
uniprot id: M0JZU0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS20800
gene id: 662476:KDQ40_RS20800
uniprot id: M0JNC5
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS10600
gene id: 662476:KDQ40_RS10600
uniprot id: M0JWS8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS21685
gene id: 662476:KDQ40_RS21685
uniprot id: M0JEP4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS14930
gene id: 662476:KDQ40_RS14930
uniprot id: M0K171
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

662476:KDQ40 RS06775
gene id: 662476:KDQ40_RS06775
uniprot id: M0JZ03
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

662476:KDQ40 RS14000
gene id: 662476:KDQ40_RS14000
uniprot id: M0K1Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

662476:KDQ40 RS00675
gene id: 662476:KDQ40_RS00675
uniprot id: M0K329
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS09210
gene id: 662476:KDQ40_RS09210
uniprot id: M0JYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

662476:KDQ40 RS18115
gene id: 662476:KDQ40_RS18115
uniprot id: M0JJM4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

662476:KDQ40 RS07645
gene id: 662476:KDQ40_RS07645
uniprot id: M0JWA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

662476:KDQ40 RS12940
gene id: 662476:KDQ40_RS12940
uniprot id: M0JZ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

662476:KDQ40 RS06320
gene id: 662476:KDQ40_RS06320
uniprot id: M0K193
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

662476:KDQ40 RS15320
gene id: 662476:KDQ40_RS15320
uniprot id: M0K103
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

662476:KDQ40 RS04350
gene id: 662476:KDQ40_RS04350
uniprot id: M0K1Q4
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

662476:KDQ40 RS12765
gene id: 662476:KDQ40_RS12765
uniprot id: M0K0Z6
names: Similarity
messages: Belongs to the thioesterase PaaI family.

662476:KDQ40 RS12870
gene id: 662476:KDQ40_RS12870
uniprot id: M0JZN5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

662476:KDQ40 RS06690
gene id: 662476:KDQ40_RS06690
uniprot id: M0JX00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS03785
gene id: 662476:KDQ40_RS03785
uniprot id: M0K8M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

662476:KDQ40 RS12970
gene id: 662476:KDQ40_RS12970
uniprot id: M0JZK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

662476:KDQ40 RS14010
gene id: 662476:KDQ40_RS14010
uniprot id: M0K0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

662476:KDQ40 RS15350
gene id: 662476:KDQ40_RS15350
uniprot id: M0K1L6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

662476:KDQ40 RS20030
gene id: 662476:KDQ40_RS20030
uniprot id: M0JQ09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS11105
gene id: 662476:KDQ40_RS11105
uniprot id: M0JUW3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS23015
gene id: 662476:KDQ40_RS23015
uniprot id: M0JMG4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS19640
gene id: 662476:KDQ40_RS19640
uniprot id: M0JP28
names: Similarity
messages: Belongs to the RutC family.

662476:KDQ40 RS21035
gene id: 662476:KDQ40_RS21035
uniprot id: M0JKY0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

662476:KDQ40 RS00735
gene id: 662476:KDQ40_RS00735
uniprot id: M0K6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

662476:KDQ40 RS12140
gene id: 662476:KDQ40_RS12140
uniprot id: M0JST2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS19725
gene id: 662476:KDQ40_RS19725
uniprot id: M0JQU4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

662476:KDQ40 RS07285
gene id: 662476:KDQ40_RS07285
uniprot id: M0JZ92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08345
gene id: 662476:KDQ40_RS08345
uniprot id: M0JZR4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

662476:KDQ40 RS15555
gene id: 662476:KDQ40_RS15555
uniprot id: M0K1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

662476:KDQ40 RS05335
gene id: 662476:KDQ40_RS05335
uniprot id: M0JWS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

662476:KDQ40 RS05575
gene id: 662476:KDQ40_RS05575
uniprot id: M0JZZ9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02470
gene id: 662476:KDQ40_RS02470
uniprot id: M0K4N7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

662476:KDQ40 RS16250
gene id: 662476:KDQ40_RS16250
uniprot id: M0JQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS00325
gene id: 662476:KDQ40_RS00325
uniprot id: M0K390
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS19795
gene id: 662476:KDQ40_RS19795
uniprot id: M0JNQ8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

662476:KDQ40 RS04460
gene id: 662476:KDQ40_RS04460
uniprot id: M0JYJ8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

662476:KDQ40 RS10925
gene id: 662476:KDQ40_RS10925
uniprot id: M0JVB3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06680
gene id: 662476:KDQ40_RS06680
uniprot id: M0K1F5
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Tetramer of two components I and two components II.

662476:KDQ40 RS06720
gene id: 662476:KDQ40_RS06720
uniprot id: M0JYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

662476:KDQ40 RS11295
gene id: 662476:KDQ40_RS11295
uniprot id: M0JSW6
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

662476:KDQ40 RS13150
gene id: 662476:KDQ40_RS13150
uniprot id: M0K2L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

662476:KDQ40 RS16010
gene id: 662476:KDQ40_RS16010
uniprot id: M0K371
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

662476:KDQ40 RS16160
gene id: 662476:KDQ40_RS16160
uniprot id: M0JS04
names: Similarity
messages: Belongs to the SELO family.

662476:KDQ40 RS08535
gene id: 662476:KDQ40_RS08535
uniprot id: M0JVC0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

662476:KDQ40 RS07955
gene id: 662476:KDQ40_RS07955
uniprot id: M0JX80
names: Similarity
messages: Belongs to the HerA family.

662476:KDQ40 RS03255
gene id: 662476:KDQ40_RS03255
uniprot id: M0K807
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12040
gene id: 662476:KDQ40_RS12040
uniprot id: M0JSR3
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

662476:KDQ40 RS16400
gene id: 662476:KDQ40_RS16400
uniprot id: M0JQL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS04170
gene id: 662476:KDQ40_RS04170
uniprot id: M0KBL8
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS01370
gene id: 662476:KDQ40_RS01370
uniprot id: M0K5L4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS01130
gene id: 662476:KDQ40_RS01130
uniprot id: M0K271
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04870
gene id: 662476:KDQ40_RS04870
uniprot id: M0JY47
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS17215
gene id: 662476:KDQ40_RS17215
uniprot id: M0JLE3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS14015
gene id: 662476:KDQ40_RS14015
uniprot id: M0K4N3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS22335
gene id: 662476:KDQ40_RS22335
uniprot id: M0JQJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS15775
gene id: 662476:KDQ40_RS15775
uniprot id: M0K5D9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

662476:KDQ40 RS06630
gene id: 662476:KDQ40_RS06630
uniprot id: M0K1E4
names: Similarity
messages: Belongs to the DNA photolyase family.

662476:KDQ40 RS22945
gene id: 662476:KDQ40_RS22945
uniprot id: M0JXT5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS16935
gene id: 662476:KDQ40_RS16935
uniprot id: M0JIC5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10455
gene id: 662476:KDQ40_RS10455
uniprot id: M0JXX5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04410
gene id: 662476:KDQ40_RS04410
uniprot id: M0JYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

662476:KDQ40 RS08575
gene id: 662476:KDQ40_RS08575
uniprot id: M0JZU6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15200
gene id: 662476:KDQ40_RS15200
uniprot id: M0K5N3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

662476:KDQ40 RS03120
gene id: 662476:KDQ40_RS03120
uniprot id: M0K535
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

662476:KDQ40 RS11270
gene id: 662476:KDQ40_RS11270
uniprot id: M0JSW1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

662476:KDQ40 RS15175
gene id: 662476:KDQ40_RS15175
uniprot id: M0K5N6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS14270
gene id: 662476:KDQ40_RS14270
uniprot id: M0K3P7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662476:KDQ40 RS15790
gene id: 662476:KDQ40_RS15790
uniprot id: M0K0T8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06085
gene id: 662476:KDQ40_RS06085
uniprot id: M0K0B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

662476:KDQ40 RS01955
gene id: 662476:KDQ40_RS01955
uniprot id: M0K354
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

662476:KDQ40 RS22540
gene id: 662476:KDQ40_RS22540
uniprot id: M0JM37
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS00610
gene id: 662476:KDQ40_RS00610
uniprot id: M0K623
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

662476:KDQ40 RS19335
gene id: 662476:KDQ40_RS19335
uniprot id: M0JSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS16925
gene id: 662476:KDQ40_RS16925
uniprot id: M0JLK3
names: Similarity
messages: Belongs to the peptidase S45 family.

662476:KDQ40 RS08645
gene id: 662476:KDQ40_RS08645
uniprot id: M0JYW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS04555
gene id: 662476:KDQ40_RS04555
uniprot id: M0K2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

662476:KDQ40 RS02275
gene id: 662476:KDQ40_RS02275
uniprot id: M0K2Z0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS15180
gene id: 662476:KDQ40_RS15180
uniprot id: M0K4R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

662476:KDQ40 RS02485
gene id: 662476:KDQ40_RS02485
uniprot id: M0K3J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

662476:KDQ40 RS13015
gene id: 662476:KDQ40_RS13015
uniprot id: M0JZJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08335
gene id: 662476:KDQ40_RS08335
uniprot id: M0JXE2
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12780
gene id: 662476:KDQ40_RS12780
uniprot id: M0K3M0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662476:KDQ40 RS08595
gene id: 662476:KDQ40_RS08595
uniprot id: M0JYV4
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

662476:KDQ40 RS01190
gene id: 662476:KDQ40_RS01190
uniprot id: M0K6N1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

662476:KDQ40 RS13785
gene id: 662476:KDQ40_RS13785
uniprot id: M0JZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

662476:KDQ40 RS16860
gene id: 662476:KDQ40_RS16860
uniprot id: M0JIE1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS01810
gene id: 662476:KDQ40_RS01810
uniprot id: M0K392
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

662476:KDQ40 RS19490
gene id: 662476:KDQ40_RS19490
uniprot id: M0JNZ2
names: Similarity
messages: Belongs to the GcvT family.

662476:KDQ40 RS02675
gene id: 662476:KDQ40_RS02675
uniprot id: M0K4U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

662476:KDQ40 RS09870
gene id: 662476:KDQ40_RS09870
uniprot id: M0JWE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS15395
gene id: 662476:KDQ40_RS15395
uniprot id: M0K0Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS01050
gene id: 662476:KDQ40_RS01050
uniprot id: M0K417
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662476:KDQ40 RS02920
gene id: 662476:KDQ40_RS02920
uniprot id: M0K954
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

662476:KDQ40 RS05970
gene id: 662476:KDQ40_RS05970
uniprot id: M0JX77
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

662476:KDQ40 RS09335
gene id: 662476:KDQ40_RS09335
uniprot id: M0JYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS16180
gene id: 662476:KDQ40_RS16180
uniprot id: M0JRH6
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS16890
gene id: 662476:KDQ40_RS16890
uniprot id: M0JIQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662476:KDQ40 RS14655
gene id: 662476:KDQ40_RS14655
uniprot id: M0JZS3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS15030
gene id: 662476:KDQ40_RS15030
uniprot id: M0K150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14935
gene id: 662476:KDQ40_RS14935
uniprot id: M0K1T9
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

662476:KDQ40 RS14675
gene id: 662476:KDQ40_RS14675
uniprot id: M0K3H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

662476:KDQ40 RS01340
gene id: 662476:KDQ40_RS01340
uniprot id: M0K6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

662476:KDQ40 RS05665
gene id: 662476:KDQ40_RS05665
uniprot id: M0JWH7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS11610
gene id: 662476:KDQ40_RS11610
uniprot id: M0JUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

662476:KDQ40 RS11710
gene id: 662476:KDQ40_RS11710
uniprot id: M0JUT9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS03335
gene id: 662476:KDQ40_RS03335
uniprot id: M0K640
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09395
gene id: 662476:KDQ40_RS09395
uniprot id: M0JTZ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

662476:KDQ40 RS12145
gene id: 662476:KDQ40_RS12145
uniprot id: M0JV12
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07425
gene id: 662476:KDQ40_RS07425
uniprot id: M0K1V6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS00925
gene id: 662476:KDQ40_RS00925
uniprot id: M0K438
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS03175
gene id: 662476:KDQ40_RS03175
uniprot id: M0K820
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

662476:KDQ40 RS01995
gene id: 662476:KDQ40_RS01995
uniprot id: A0A8T8KI46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS10835
gene id: 662476:KDQ40_RS10835
uniprot id: M0JY56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02705
gene id: 662476:KDQ40_RS02705
uniprot id: M0K5B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

662476:KDQ40 RS01035
gene id: 662476:KDQ40_RS01035
uniprot id: M0K2X4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

662476:KDQ40 RS11850
gene id: 662476:KDQ40_RS11850
uniprot id: M0JT62
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

662476:KDQ40 RS10425
gene id: 662476:KDQ40_RS10425
uniprot id: M0JWP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS08585
gene id: 662476:KDQ40_RS08585
uniprot id: A0A8T8KC50
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08090
gene id: 662476:KDQ40_RS08090
uniprot id: M0JYL0
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

662476:KDQ40 RS00930
gene id: 662476:KDQ40_RS00930
uniprot id: M0K2A5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

662476:KDQ40 RS14155
gene id: 662476:KDQ40_RS14155
uniprot id: M0K011
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06385
gene id: 662476:KDQ40_RS06385
uniprot id: M0JYT6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS06335
gene id: 662476:KDQ40_RS06335
uniprot id: M0JYS5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS17850
gene id: 662476:KDQ40_RS17850
uniprot id: M0JMG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS10820
gene id: 662476:KDQ40_RS10820
uniprot id: M0JV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02430
gene id: 662476:KDQ40_RS02430
uniprot id: M0K3K4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10505
gene id: 662476:KDQ40_RS10505
uniprot id: M0JXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS00760
gene id: 662476:KDQ40_RS00760
uniprot id: M0K6W3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

662476:KDQ40 RS03545
gene id: 662476:KDQ40_RS03545
uniprot id: M0K5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS01975
gene id: 662476:KDQ40_RS01975
uniprot id: M0K348
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

662476:KDQ40 RS00285
gene id: 662476:KDQ40_RS00285
uniprot id: M0K685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662476:KDQ40 RS07595
gene id: 662476:KDQ40_RS07595
uniprot id: M0JW93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

662476:KDQ40 RS01985
gene id: 662476:KDQ40_RS01985
uniprot id: M0K7R5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02325
gene id: 662476:KDQ40_RS02325
uniprot id: M0K2Y2
names: Similarity
messages: Belongs to the UPF0175 family.

662476:KDQ40 RS19655
gene id: 662476:KDQ40_RS19655
uniprot id: M0JRZ0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS20875
gene id: 662476:KDQ40_RS20875
uniprot id: M0JND5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07520
gene id: 662476:KDQ40_RS07520
uniprot id: M0K1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

662476:KDQ40 RS13310
gene id: 662476:KDQ40_RS13310
uniprot id: M0JYW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS19325
gene id: 662476:KDQ40_RS19325
uniprot id: M0JQN2
names: Subunit
messages: Homotetramer.

662476:KDQ40 RS07640
gene id: 662476:KDQ40_RS07640
uniprot id: M0K070
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

662476:KDQ40 RS02925
gene id: 662476:KDQ40_RS02925
uniprot id: M0K868
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

662476:KDQ40 RS10000
gene id: 662476:KDQ40_RS10000
uniprot id: M0JXM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662476:KDQ40 RS01470
gene id: 662476:KDQ40_RS01470
uniprot id: M0K5J4
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS09995
gene id: 662476:KDQ40_RS09995
uniprot id: M0JWG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09440
gene id: 662476:KDQ40_RS09440
uniprot id: M0JXB8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

662476:KDQ40 RS10515
gene id: 662476:KDQ40_RS10515
uniprot id: M0JV23
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

662476:KDQ40 RS00685
gene id: 662476:KDQ40_RS00685
uniprot id: M0K610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS05390
gene id: 662476:KDQ40_RS05390
uniprot id: M0JW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

662476:KDQ40 RS08795
gene id: 662476:KDQ40_RS08795
uniprot id: M0JYZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the Tfx family.
messages: Putative transcriptional regulator.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS16485
gene id: 662476:KDQ40_RS16485
uniprot id: M0JTH7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07180
gene id: 662476:KDQ40_RS07180
uniprot id: M0JX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

662476:KDQ40 RS01305
gene id: 662476:KDQ40_RS01305
uniprot id: M0K218
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS09070
gene id: 662476:KDQ40_RS09070
uniprot id: M0JX58
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

662476:KDQ40 RS10260
gene id: 662476:KDQ40_RS10260
uniprot id: M0JYX9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06300
gene id: 662476:KDQ40_RS06300
uniprot id: M0JXD6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

662476:KDQ40 RS06135
gene id: 662476:KDQ40_RS06135
uniprot id: M0K0C7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS17650
gene id: 662476:KDQ40_RS17650
uniprot id: M0JMJ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS01430
gene id: 662476:KDQ40_RS01430
uniprot id: M0K1Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

662476:KDQ40 RS07025
gene id: 662476:KDQ40_RS07025
uniprot id: M0JZ47
names: Similarity
messages: Belongs to the peptidase S49 family.

662476:KDQ40 RS06270
gene id: 662476:KDQ40_RS06270
uniprot id: M0K186
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

662476:KDQ40 RS05165
gene id: 662476:KDQ40_RS05165
uniprot id: M0K212
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS10280
gene id: 662476:KDQ40_RS10280
uniprot id: M0JYY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

662476:KDQ40 RS02060
gene id: 662476:KDQ40_RS02060
uniprot id: M0K6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

662476:KDQ40 RS20320
gene id: 662476:KDQ40_RS20320
uniprot id: M0JQ61
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS02170
gene id: 662476:KDQ40_RS02170
uniprot id: M0K307
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

662476:KDQ40 RS19395
gene id: 662476:KDQ40_RS19395
uniprot id: M0JNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

662476:KDQ40 RS13585
gene id: 662476:KDQ40_RS13585
uniprot id: M0K1B0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13815
gene id: 662476:KDQ40_RS13815
uniprot id: M0K004
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

662476:KDQ40 RS19865
gene id: 662476:KDQ40_RS19865
uniprot id: M0JRP5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS00765
gene id: 662476:KDQ40_RS00765
uniprot id: M0K5Z6
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

662476:KDQ40 RS05580
gene id: 662476:KDQ40_RS05580
uniprot id: M0K0W2
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS03570
gene id: 662476:KDQ40_RS03570
uniprot id: M0K5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

662476:KDQ40 RS04895
gene id: 662476:KDQ40_RS04895
uniprot id: M0JY53
names: Similarity
messages: Belongs to the UPF0284 family.

662476:KDQ40 RS22195
gene id: 662476:KDQ40_RS22195
uniprot id: M0JG60
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13865
gene id: 662476:KDQ40_RS13865
uniprot id: M0K3B9
names: Similarity
messages: Belongs to the aspartokinase family.

662476:KDQ40 RS01435
gene id: 662476:KDQ40_RS01435
uniprot id: M0K2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

662476:KDQ40 RS16410
gene id: 662476:KDQ40_RS16410
uniprot id: A0A8T8KL28
names: Similarity
messages: Belongs to the UPF0175 family.

662476:KDQ40 RS03535
gene id: 662476:KDQ40_RS03535
uniprot id: M0K8S8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS07235
gene id: 662476:KDQ40_RS07235
uniprot id: M0JZ82
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

662476:KDQ40 RS03530
gene id: 662476:KDQ40_RS03530
uniprot id: M0K4W5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS02855
gene id: 662476:KDQ40_RS02855
uniprot id: M0K6D7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS19575
gene id: 662476:KDQ40_RS19575
uniprot id: M0JQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS10595
gene id: 662476:KDQ40_RS10595
uniprot id: M0JUJ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662476:KDQ40 RS12890
gene id: 662476:KDQ40_RS12890
uniprot id: M0JZ54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

662476:KDQ40 RS01835
gene id: 662476:KDQ40_RS01835
uniprot id: M0K386
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS08480
gene id: 662476:KDQ40_RS08480
uniprot id: M0JVB0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

662476:KDQ40 RS10655
gene id: 662476:KDQ40_RS10655
uniprot id: M0JWT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

662476:KDQ40 RS11425
gene id: 662476:KDQ40_RS11425
uniprot id: M0JSY9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

662476:KDQ40 RS02990
gene id: 662476:KDQ40_RS02990
uniprot id: M0K4M0
names: Similarity
messages: Belongs to the TrpF family.

662476:KDQ40 RS06450
gene id: 662476:KDQ40_RS06450
uniprot id: M0JXG1
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19570
gene id: 662476:KDQ40_RS19570
uniprot id: A0A8T8KL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS01265
gene id: 662476:KDQ40_RS01265
uniprot id: M0K6L4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

662476:KDQ40 RS06825
gene id: 662476:KDQ40_RS06825
uniprot id: M0JZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

662476:KDQ40 RS06230
gene id: 662476:KDQ40_RS06230
uniprot id: M0JXB9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

662476:KDQ40 RS04225
gene id: 662476:KDQ40_RS04225
uniprot id: M0KAN9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS00670
gene id: 662476:KDQ40_RS00670
uniprot id: M0K2D6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS15205
gene id: 662476:KDQ40_RS15205
uniprot id: M0K4R6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS22565
gene id: 662476:KDQ40_RS22565
uniprot id: M0JM93
names: Similarity
messages: Belongs to the MCM family.

662476:KDQ40 RS20865
gene id: 662476:KDQ40_RS20865
uniprot id: M0JSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662476:KDQ40 RS13660
gene id: 662476:KDQ40_RS13660
uniprot id: M0JZH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

662476:KDQ40 RS08275
gene id: 662476:KDQ40_RS08275
uniprot id: M0JVR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS06440
gene id: 662476:KDQ40_RS06440
uniprot id: M0K0I2
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS05945
gene id: 662476:KDQ40_RS05945
uniprot id: M0JX75
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

662476:KDQ40 RS08755
gene id: 662476:KDQ40_RS08755
uniprot id: M0JVZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

662476:KDQ40 RS21895
gene id: 662476:KDQ40_RS21895
uniprot id: M0JER6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS01225
gene id: 662476:KDQ40_RS01225
uniprot id: M0K3W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS12535
gene id: 662476:KDQ40_RS12535
uniprot id: M0K225
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04355
gene id: 662476:KDQ40_RS04355
uniprot id: M0K2H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

662476:KDQ40 RS15580
gene id: 662476:KDQ40_RS15580
uniprot id: M0K0W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

662476:KDQ40 RS12600
gene id: 662476:KDQ40_RS12600
uniprot id: M0JYV1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

662476:KDQ40 RS11580
gene id: 662476:KDQ40_RS11580
uniprot id: M0JSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

662476:KDQ40 RS21350
gene id: 662476:KDQ40_RS21350
uniprot id: M0JGY0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09215
gene id: 662476:KDQ40_RS09215
uniprot id: M0JUE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

662476:KDQ40 RS04965
gene id: 662476:KDQ40_RS04965
uniprot id: M0JZJ9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

662476:KDQ40 RS09725
gene id: 662476:KDQ40_RS09725
uniprot id: M0JYL6
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS01390
gene id: 662476:KDQ40_RS01390
uniprot id: A0A8T8KHC1
names: Similarity
messages: Belongs to the glutaredoxin family.

662476:KDQ40 RS10225
gene id: 662476:KDQ40_RS10225
uniprot id: M0JWK0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

662476:KDQ40 RS13925
gene id: 662476:KDQ40_RS13925
uniprot id: M0K061
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

662476:KDQ40 RS08525
gene id: 662476:KDQ40_RS08525
uniprot id: M0JVV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02625
gene id: 662476:KDQ40_RS02625
uniprot id: M0K4V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

662476:KDQ40 RS15005
gene id: 662476:KDQ40_RS15005
uniprot id: M0K157
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

662476:KDQ40 RS09590
gene id: 662476:KDQ40_RS09590
uniprot id: M0JXE4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

662476:KDQ40 RS12830
gene id: 662476:KDQ40_RS12830
uniprot id: M0K2T7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

662476:KDQ40 RS03450
gene id: 662476:KDQ40_RS03450
uniprot id: M0K4X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

662476:KDQ40 RS19895
gene id: 662476:KDQ40_RS19895
uniprot id: M0JSX7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10530
gene id: 662476:KDQ40_RS10530
uniprot id: M0JXZ2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS12370
gene id: 662476:KDQ40_RS12370
uniprot id: M0JTG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

662476:KDQ40 RS14470
gene id: 662476:KDQ40_RS14470
uniprot id: M0K3L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

662476:KDQ40 RS00385
gene id: 662476:KDQ40_RS00385
uniprot id: M0K666
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

662476:KDQ40 RS15690
gene id: 662476:KDQ40_RS15690
uniprot id: M0K0V3
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

662476:KDQ40 RS11545
gene id: 662476:KDQ40_RS11545
uniprot id: M0JWV1
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19660
gene id: 662476:KDQ40_RS19660
uniprot id: M0JST8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

662476:KDQ40 RS10195
gene id: 662476:KDQ40_RS10195
uniprot id: M0JUD0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS10215
gene id: 662476:KDQ40_RS10215
uniprot id: M0QTC3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS18545
gene id: 662476:KDQ40_RS18545
uniprot id: A0A8T8KI29
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15345
gene id: 662476:KDQ40_RS15345
uniprot id: M0K0Z9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

662476:KDQ40 RS07925
gene id: 662476:KDQ40_RS07925
uniprot id: M0JVK5
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

662476:KDQ40 RS11290
gene id: 662476:KDQ40_RS11290
uniprot id: A0A8T8KED1
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

662476:KDQ40 RS10325
gene id: 662476:KDQ40_RS10325
uniprot id: M0JXU6
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

662476:KDQ40 RS04930
gene id: 662476:KDQ40_RS04930
uniprot id: M0JY59
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS05980
gene id: 662476:KDQ40_RS05980
uniprot id: M0JYL3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

662476:KDQ40 RS18595
gene id: 662476:KDQ40_RS18595
uniprot id: M0JJK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

662476:KDQ40 RS04790
gene id: 662476:KDQ40_RS04790
uniprot id: M0K220
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS11350
gene id: 662476:KDQ40_RS11350
uniprot id: M0JSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Membrane

662476:KDQ40 RS19735
gene id: 662476:KDQ40_RS19735
uniprot id: M0JSV3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS01360
gene id: 662476:KDQ40_RS01360
uniprot id: M0K2L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS03260
gene id: 662476:KDQ40_RS03260
uniprot id: M0K655
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12760
gene id: 662476:KDQ40_RS12760
uniprot id: M0K2V1
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS02690
gene id: 662476:KDQ40_RS02690
uniprot id: M0K8C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

662476:KDQ40 RS19925
gene id: 662476:KDQ40_RS19925
uniprot id: M0JTQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02495
gene id: 662476:KDQ40_RS02495
uniprot id: M0K6J0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12795
gene id: 662476:KDQ40_RS12795
uniprot id: M0JZ75
names: Similarity
messages: Belongs to the AAA ATPase family.

662476:KDQ40 RS19330
gene id: 662476:KDQ40_RS19330
uniprot id: M0JRS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03700
gene id: 662476:KDQ40_RS03700
uniprot id: M0K464
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14620
gene id: 662476:KDQ40_RS14620
uniprot id: M0K4A3
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS05020
gene id: 662476:KDQ40_RS05020
uniprot id: A0A8T8KGI9
names: Similarity
messages: Belongs to the UPF0047 family.

662476:KDQ40 RS05820
gene id: 662476:KDQ40_RS05820
uniprot id: M0JYI7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS11370
gene id: 662476:KDQ40_RS11370
uniprot id: M0JWR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

662476:KDQ40 RS00200
gene id: 662476:KDQ40_RS00200
uniprot id: M0K1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

662476:KDQ40 RS03055
gene id: 662476:KDQ40_RS03055
uniprot id: M0K842
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS00920
gene id: 662476:KDQ40_RS00920
uniprot id: M0K5X1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS07675
gene id: 662476:KDQ40_RS07675
uniprot id: M0JVP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS05000
gene id: 662476:KDQ40_RS05000
uniprot id: M0K1D3
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

662476:KDQ40 RS05710
gene id: 662476:KDQ40_RS05710
uniprot id: A0A8T8KDW6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS20200
gene id: 662476:KDQ40_RS20200
uniprot id: M0JPQ9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06780
gene id: 662476:KDQ40_RS06780
uniprot id: M0K0P1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS17050
gene id: 662476:KDQ40_RS17050
uniprot id: M0JLH9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

662476:KDQ40 RS00120
gene id: 662476:KDQ40_RS00120
uniprot id: M0K1Y2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS12355
gene id: 662476:KDQ40_RS12355
uniprot id: M0JV42
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

662476:KDQ40 RS17045
gene id: 662476:KDQ40_RS17045
uniprot id: M0JME5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

662476:KDQ40 RS01285
gene id: 662476:KDQ40_RS01285
uniprot id: M0K2N5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

662476:KDQ40 RS03370
gene id: 662476:KDQ40_RS03370
uniprot id: M0K4Z3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS10630
gene id: 662476:KDQ40_RS10630
uniprot id: M0JWT3
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

662476:KDQ40 RS05380
gene id: 662476:KDQ40_RS05380
uniprot id: M0K0R5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13375
gene id: 662476:KDQ40_RS13375
uniprot id: M0K1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

662476:KDQ40 RS03560
gene id: 662476:KDQ40_RS03560
uniprot id: M0K8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS00445
gene id: 662476:KDQ40_RS00445
uniprot id: M0K2H2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS09505
gene id: 662476:KDQ40_RS09505
uniprot id: M0JU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

662476:KDQ40 RS10775
gene id: 662476:KDQ40_RS10775
uniprot id: M0JUQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

662476:KDQ40 RS02730
gene id: 662476:KDQ40_RS02730
uniprot id: M0K5A2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS08015
gene id: 662476:KDQ40_RS08015
uniprot id: M0JYI9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

662476:KDQ40 RS05515
gene id: 662476:KDQ40_RS05515
uniprot id: M0JWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

662476:KDQ40 RS08635
gene id: 662476:KDQ40_RS08635
uniprot id: M0JVD6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08145
gene id: 662476:KDQ40_RS08145
uniprot id: M0JZN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

662476:KDQ40 RS01495
gene id: 662476:KDQ40_RS01495
uniprot id: M0K2T3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS05405
gene id: 662476:KDQ40_RS05405
uniprot id: M0K0R9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02000
gene id: 662476:KDQ40_RS02000
uniprot id: M0K341
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS10170
gene id: 662476:KDQ40_RS10170
uniprot id: M0JUC4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS12350
gene id: 662476:KDQ40_RS12350
uniprot id: M0JSX3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

662476:KDQ40 RS14185
gene id: 662476:KDQ40_RS14185
uniprot id: M0K0P3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

662476:KDQ40 RS09785
gene id: 662476:KDQ40_RS09785
uniprot id: M0JU56
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15100
gene id: 662476:KDQ40_RS15100
uniprot id: M0K2X6
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

662476:KDQ40 RS04115
gene id: 662476:KDQ40_RS04115
uniprot id: M0K783
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

662476:KDQ40 RS11695
gene id: 662476:KDQ40_RS11695
uniprot id: M0JWX6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

662476:KDQ40 RS16730
gene id: 662476:KDQ40_RS16730
uniprot id: M0JIG8
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS13165
gene id: 662476:KDQ40_RS13165
uniprot id: M0JZG3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS07620
gene id: 662476:KDQ40_RS07620
uniprot id: M0JW98
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS18215
gene id: 662476:KDQ40_RS18215
uniprot id: M0JFW0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS20125
gene id: 662476:KDQ40_RS20125
uniprot id: M0JTU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS10250
gene id: 662476:KDQ40_RS10250
uniprot id: M0JWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

662476:KDQ40 RS14890
gene id: 662476:KDQ40_RS14890
uniprot id: M0K5T5
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

662476:KDQ40 RS19935
gene id: 662476:KDQ40_RS19935
uniprot id: A0A8T8KTM0
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS14360
gene id: 662476:KDQ40_RS14360
uniprot id: M0K0K9
names: Similarity
messages: Belongs to the IMPACT family.

662476:KDQ40 RS11355
gene id: 662476:KDQ40_RS11355
uniprot id: M0JSF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS05245
gene id: 662476:KDQ40_RS05245
uniprot id: M0JY63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS17265
gene id: 662476:KDQ40_RS17265
uniprot id: M0JJ62
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

662476:KDQ40 RS07210
gene id: 662476:KDQ40_RS07210
uniprot id: M0JZ77
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS02400
gene id: 662476:KDQ40_RS02400
uniprot id: M0K2W5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS10965
gene id: 662476:KDQ40_RS10965
uniprot id: M0JWZ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662476:KDQ40 RS03285
gene id: 662476:KDQ40_RS03285
uniprot id: M0K650
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

662476:KDQ40 RS17185
gene id: 662476:KDQ40_RS17185
uniprot id: M0JLE7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

662476:KDQ40 RS13920
gene id: 662476:KDQ40_RS13920
uniprot id: M0K206
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS14975
gene id: 662476:KDQ40_RS14975
uniprot id: M0K300
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS01840
gene id: 662476:KDQ40_RS01840
uniprot id: M0K3X7
names: Similarity
messages: Belongs to the arginase family.

662476:KDQ40 RS16255
gene id: 662476:KDQ40_RS16255
uniprot id: M0JU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS10340
gene id: 662476:KDQ40_RS10340
uniprot id: M0JUF5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

662476:KDQ40 RS05325
gene id: 662476:KDQ40_RS05325
uniprot id: M0JZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS20620
gene id: 662476:KDQ40_RS20620
uniprot id: M0JNN6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS03690
gene id: 662476:KDQ40_RS03690
uniprot id: M0K7T9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

662476:KDQ40 RS05445
gene id: 662476:KDQ40_RS05445
uniprot id: M0JYA8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

662476:KDQ40 RS14955
gene id: 662476:KDQ40_RS14955
uniprot id: M0K164
names: Similarity
messages: Belongs to the proline racemase family.

662476:KDQ40 RS15110
gene id: 662476:KDQ40_RS15110
uniprot id: M0K1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

662476:KDQ40 RS15370
gene id: 662476:KDQ40_RS15370
uniprot id: M0K0Z4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

662476:KDQ40 RS15185
gene id: 662476:KDQ40_RS15185
uniprot id: M0K2W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS09460
gene id: 662476:KDQ40_RS09460
uniprot id: M0JW74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS00350
gene id: 662476:KDQ40_RS00350
uniprot id: M0K384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

662476:KDQ40 RS09760
gene id: 662476:KDQ40_RS09760
uniprot id: M0JU52
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS01575
gene id: 662476:KDQ40_RS01575
uniprot id: M0K3G7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS08875
gene id: 662476:KDQ40_RS08875
uniprot id: M0JZZ3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02940
gene id: 662476:KDQ40_RS02940
uniprot id: M0K566
names: Similarity
messages: Belongs to the LarC family.

662476:KDQ40 RS01125
gene id: 662476:KDQ40_RS01125
uniprot id: M0K401
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS07605
gene id: 662476:KDQ40_RS07605
uniprot id: M0JXS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

662476:KDQ40 RS00950
gene id: 662476:KDQ40_RS00950
uniprot id: M0K433
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS15340
gene id: 662476:KDQ40_RS15340
uniprot id: M0K2T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662476:KDQ40 RS07725
gene id: 662476:KDQ40_RS07725
uniprot id: M0JVQ9
names: Similarity
messages: Belongs to the peptidase C56 family.

662476:KDQ40 RS11460
gene id: 662476:KDQ40_RS11460
uniprot id: M0JUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS14255
gene id: 662476:KDQ40_RS14255
uniprot id: M0JZZ1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

662476:KDQ40 RS09945
gene id: 662476:KDQ40_RS09945
uniprot id: M0JWF3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662476:KDQ40 RS05715
gene id: 662476:KDQ40_RS05715
uniprot id: M0JWI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS20855
gene id: 662476:KDQ40_RS20855
uniprot id: M0JQK1
names: Similarity
messages: Belongs to the arginase family.

662476:KDQ40 RS11705
gene id: 662476:KDQ40_RS11705
uniprot id: M0JSK8
names: Similarity
messages: Belongs to the UPF0201 family.

662476:KDQ40 RS05990
gene id: 662476:KDQ40_RS05990
uniprot id: M0K145
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

662476:KDQ40 RS12925
gene id: 662476:KDQ40_RS12925
uniprot id: M0K3J1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS11320
gene id: 662476:KDQ40_RS11320
uniprot id: M0JSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662476:KDQ40 RS08825
gene id: 662476:KDQ40_RS08825
uniprot id: M0JZY6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS05125
gene id: 662476:KDQ40_RS05125
uniprot id: M0JXL6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07950
gene id: 662476:KDQ40_RS07950
uniprot id: M0JV22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

662476:KDQ40 RS02130
gene id: 662476:KDQ40_RS02130
uniprot id: M0K7N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS19700
gene id: 662476:KDQ40_RS19700
uniprot id: M0JQU1
names: Similarity
messages: Belongs to the RutC family.

662476:KDQ40 RS15935
gene id: 662476:KDQ40_RS15935
uniprot id: M0K2H4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

662476:KDQ40 RS08150
gene id: 662476:KDQ40_RS08150
uniprot id: M0JVP5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

662476:KDQ40 RS15040
gene id: 662476:KDQ40_RS15040
uniprot id: M0K5Q7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

662476:KDQ40 RS12685
gene id: 662476:KDQ40_RS12685
uniprot id: M0K2W7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

662476:KDQ40 RS02190
gene id: 662476:KDQ40_RS02190
uniprot id: M0K4U3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06705
gene id: 662476:KDQ40_RS06705
uniprot id: M0K1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

662476:KDQ40 RS18635
gene id: 662476:KDQ40_RS18635
uniprot id: M0JGN4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS08555
gene id: 662476:KDQ40_RS08555
uniprot id: M0JVW0
names: Function
messages: Part of a potassium transport system.

662476:KDQ40 RS14445
gene id: 662476:KDQ40_RS14445
uniprot id: M0K3L4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

662476:KDQ40 RS06470
gene id: 662476:KDQ40_RS06470
uniprot id: M0JXG6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

662476:KDQ40 RS11020
gene id: 662476:KDQ40_RS11020
uniprot id: M0JX03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

662476:KDQ40 RS02090
gene id: 662476:KDQ40_RS02090
uniprot id: M0K4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662476:KDQ40 RS09375
gene id: 662476:KDQ40_RS09375
uniprot id: M0JW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS19915
gene id: 662476:KDQ40_RS19915
uniprot id: M0JRQ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662476:KDQ40 RS05645
gene id: 662476:KDQ40_RS05645
uniprot id: M0JYF8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

662476:KDQ40 RS04985
gene id: 662476:KDQ40_RS04985
uniprot id: M0JXS8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

662476:KDQ40 RS12090
gene id: 662476:KDQ40_RS12090
uniprot id: M0JSS2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

662476:KDQ40 RS09030
gene id: 662476:KDQ40_RS09030
uniprot id: M0JY99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS05815
gene id: 662476:KDQ40_RS05815
uniprot id: M0JWJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS16555
gene id: 662476:KDQ40_RS16555
uniprot id: M0JIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS03505
gene id: 662476:KDQ40_RS03505
uniprot id: M0K8T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

662476:KDQ40 RS13045
gene id: 662476:KDQ40_RS13045
uniprot id: M0K3G6
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

662476:KDQ40 RS08495
gene id: 662476:KDQ40_RS08495
uniprot id: M0JZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

662476:KDQ40 RS10100
gene id: 662476:KDQ40_RS10100
uniprot id: M0JWH8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS07350
gene id: 662476:KDQ40_RS07350
uniprot id: M0JXW9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS00720
gene id: 662476:KDQ40_RS00720
uniprot id: M0K468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662476:KDQ40 RS05950
gene id: 662476:KDQ40_RS05950
uniprot id: M0JWM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

662476:KDQ40 RS04530
gene id: 662476:KDQ40_RS04530
uniprot id: M0K2J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

662476:KDQ40 RS04585
gene id: 662476:KDQ40_RS04585
uniprot id: M0JYL9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS03360
gene id: 662476:KDQ40_RS03360
uniprot id: M0K634
names: Similarity
messages: Belongs to the DMRL synthase family.

662476:KDQ40 RS01780
gene id: 662476:KDQ40_RS01780
uniprot id: M0K521
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS14565
gene id: 662476:KDQ40_RS14565
uniprot id: M0K4B4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

662476:KDQ40 RS04890
gene id: 662476:KDQ40_RS04890
uniprot id: M0K243
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

662476:KDQ40 RS22900
gene id: 662476:KDQ40_RS22900
uniprot id: M0JNU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS22820
gene id: 662476:KDQ40_RS22820
uniprot id: M0JLL9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13420
gene id: 662476:KDQ40_RS13420
uniprot id: M0K3A1
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

662476:KDQ40 RS05825
gene id: 662476:KDQ40_RS05825
uniprot id: M0K068
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.
messages: Belongs to the BioU family.
messages: In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662476:KDQ40 RS11535
gene id: 662476:KDQ40_RS11535
uniprot id: M0JUR0
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS05690
gene id: 662476:KDQ40_RS05690
uniprot id: M0JWI0
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

662476:KDQ40 RS16275
gene id: 662476:KDQ40_RS16275
uniprot id: M0JQH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

662476:KDQ40 RS16675
gene id: 662476:KDQ40_RS16675
uniprot id: M0JKQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS04760
gene id: 662476:KDQ40_RS04760
uniprot id: M0JYQ6
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

662476:KDQ40 RS10730
gene id: 662476:KDQ40_RS10730
uniprot id: M0JY35
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS13275
gene id: 662476:KDQ40_RS13275
uniprot id: M0K2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

662476:KDQ40 RS09275
gene id: 662476:KDQ40_RS09275
uniprot id: M0JW43
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

662476:KDQ40 RS06340
gene id: 662476:KDQ40_RS06340
uniprot id: M0K0G5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

662476:KDQ40 RS22190
gene id: 662476:KDQ40_RS22190
uniprot id: M0JH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662476:KDQ40 RS11340
gene id: 662476:KDQ40_RS11340
uniprot id: M0JWR4
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

662476:KDQ40 RS07990
gene id: 662476:KDQ40_RS07990
uniprot id: M0JYI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS11600
gene id: 662476:KDQ40_RS11600
uniprot id: M0JT16
names: Similarity
messages: Belongs to the intimin/invasin family.

662476:KDQ40 RS10085
gene id: 662476:KDQ40_RS10085
uniprot id: M0JYT9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS06090
gene id: 662476:KDQ40_RS06090
uniprot id: M0K159
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Belongs to the isochorismate synthase family.

662476:KDQ40 RS09880
gene id: 662476:KDQ40_RS09880
uniprot id: M0JYP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

662476:KDQ40 RS10265
gene id: 662476:KDQ40_RS10265
uniprot id: M0JUY3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS11750
gene id: 662476:KDQ40_RS11750
uniprot id: M0JT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

662476:KDQ40 RS04310
gene id: 662476:KDQ40_RS04310
uniprot id: M0JYH0
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

662476:KDQ40 RS06965
gene id: 662476:KDQ40_RS06965
uniprot id: M0JXP9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS16560
gene id: 662476:KDQ40_RS16560
uniprot id: M0JIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS05630
gene id: 662476:KDQ40_RS05630
uniprot id: M0K0Y8
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

662476:KDQ40 RS14635
gene id: 662476:KDQ40_RS14635
uniprot id: M0K0F6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662476:KDQ40 RS20585
gene id: 662476:KDQ40_RS20585
uniprot id: M0JRI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

662476:KDQ40 RS00375
gene id: 662476:KDQ40_RS00375
uniprot id: M0K380
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS02590
gene id: 662476:KDQ40_RS02590
uniprot id: M0K6I8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

662476:KDQ40 RS21940
gene id: 662476:KDQ40_RS21940
uniprot id: M0JBR8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS01640
gene id: 662476:KDQ40_RS01640
uniprot id: M0K2Q6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

662476:KDQ40 RS02345
gene id: 662476:KDQ40_RS02345
uniprot id: M0K4R3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS06045
gene id: 662476:KDQ40_RS06045
uniprot id: M0JX89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

662476:KDQ40 RS08230
gene id: 662476:KDQ40_RS08230
uniprot id: M0JV69
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

662476:KDQ40 RS13040
gene id: 662476:KDQ40_RS13040
uniprot id: M0JZJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

662476:KDQ40 RS03445
gene id: 662476:KDQ40_RS03445
uniprot id: M0K4B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

662476:KDQ40 RS16480
gene id: 662476:KDQ40_RS16480
uniprot id: M0JUC3
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13845
gene id: 662476:KDQ40_RS13845
uniprot id: M0K1F3
names: Similarity
messages: Belongs to the threonine synthase family.

662476:KDQ40 RS06535
gene id: 662476:KDQ40_RS06535
uniprot id: M0JWX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

662476:KDQ40 RS20455
gene id: 662476:KDQ40_RS20455
uniprot id: M0JRZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS12945
gene id: 662476:KDQ40_RS12945
uniprot id: M0JZL5
names: Subunit
messages: Homotrimer.

662476:KDQ40 RS08925
gene id: 662476:KDQ40_RS08925
uniprot id: M0K002
names: Similarity
messages: Belongs to the glutamate synthase family.

662476:KDQ40 RS18225
gene id: 662476:KDQ40_RS18225
uniprot id: M0JIQ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS15475
gene id: 662476:KDQ40_RS15475
uniprot id: M0K1J7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

662476:KDQ40 RS01280
gene id: 662476:KDQ40_RS01280
uniprot id: M0K222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

662476:KDQ40 RS01620
gene id: 662476:KDQ40_RS01620
uniprot id: M0K3F8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

662476:KDQ40 RS20600
gene id: 662476:KDQ40_RS20600
uniprot id: M0JN92
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

662476:KDQ40 RS12035
gene id: 662476:KDQ40_RS12035
uniprot id: M0JT95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

662476:KDQ40 RS07280
gene id: 662476:KDQ40_RS07280
uniprot id: M0JXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS20260
gene id: 662476:KDQ40_RS20260
uniprot id: M0JT31
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS20360
gene id: 662476:KDQ40_RS20360
uniprot id: M0JT52
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09495
gene id: 662476:KDQ40_RS09495
uniprot id: M0JYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

662476:KDQ40 RS01240
gene id: 662476:KDQ40_RS01240
uniprot id: M0K6M0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

662476:KDQ40 RS19175
gene id: 662476:KDQ40_RS19175
uniprot id: M0JRP2
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

662476:KDQ40 RS00710
gene id: 662476:KDQ40_RS00710
uniprot id: M0K6X1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

662476:KDQ40 RS15605
gene id: 662476:KDQ40_RS15605
uniprot id: M0K4K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

662476:KDQ40 RS15700
gene id: 662476:KDQ40_RS15700
uniprot id: M0K5F3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

662476:KDQ40 RS11860
gene id: 662476:KDQ40_RS11860
uniprot id: M0JUW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

662476:KDQ40 RS03015
gene id: 662476:KDQ40_RS03015
uniprot id: M0K4L6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

662476:KDQ40 RS19940
gene id: 662476:KDQ40_RS19940
uniprot id: M0JRQ6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

662476:KDQ40 RS02950
gene id: 662476:KDQ40_RS02950
uniprot id: M0K862
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

662476:KDQ40 RS10485
gene id: 662476:KDQ40_RS10485
uniprot id: M0JZ26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS03085
gene id: 662476:KDQ40_RS03085
uniprot id: M0K691
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

662476:KDQ40 RS12565
gene id: 662476:KDQ40_RS12565
uniprot id: M0K069
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS01045
gene id: 662476:KDQ40_RS01045
uniprot id: M0K5U9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

662476:KDQ40 RS09365
gene id: 662476:KDQ40_RS09365
uniprot id: M0JUG6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

662476:KDQ40 RS02025
gene id: 662476:KDQ40_RS02025
uniprot id: M0K335
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

662476:KDQ40 RS04580
gene id: 662476:KDQ40_RS04580
uniprot id: M0K2K3
names: Similarity
messages: Belongs to the FUN14 family.

662476:KDQ40 RS11440
gene id: 662476:KDQ40_RS11440
uniprot id: M0JVW1
names: Similarity
messages: Belongs to the PdaD family.

662476:KDQ40 RS00340
gene id: 662476:KDQ40_RS00340
uniprot id: M0K4C1
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

662476:KDQ40 RS02800
gene id: 662476:KDQ40_RS02800
uniprot id: M0K4R5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15730
gene id: 662476:KDQ40_RS15730
uniprot id: M0K4I3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

662476:KDQ40 RS07170
gene id: 662476:KDQ40_RS07170
uniprot id: M0K1Q0
names: Similarity
messages: Belongs to the PEPCase type 1 family.

662476:KDQ40 RS07755
gene id: 662476:KDQ40_RS07755
uniprot id: M0JXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

662476:KDQ40 RS02845
gene id: 662476:KDQ40_RS02845
uniprot id: M0K968
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS14660
gene id: 662476:KDQ40_RS14660
uniprot id: M0K0F1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

662476:KDQ40 RS01500
gene id: 662476:KDQ40_RS01500
uniprot id: M0K3H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS17995
gene id: 662476:KDQ40_RS17995
uniprot id: M0JKG2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS01910
gene id: 662476:KDQ40_RS01910
uniprot id: M0K367
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

662476:KDQ40 RS06875
gene id: 662476:KDQ40_RS06875
uniprot id: M0JX30
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04510
gene id: 662476:KDQ40_RS04510
uniprot id: M0JYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

662476:KDQ40 RS13625
gene id: 662476:KDQ40_RS13625
uniprot id: M0K366
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

662476:KDQ40 RS12990
gene id: 662476:KDQ40_RS12990
uniprot id: M0JZ32
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS14475
gene id: 662476:KDQ40_RS14475
uniprot id: M0K1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

662476:KDQ40 RS01615
gene id: 662476:KDQ40_RS01615
uniprot id: M0K2R0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

662476:KDQ40 RS02725
gene id: 662476:KDQ40_RS02725
uniprot id: M0K4T3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

662476:KDQ40 RS04575
gene id: 662476:KDQ40_RS04575
uniprot id: M0K1U2
names: Similarity
messages: Belongs to the SDO1/SBDS family.

662476:KDQ40 RS09040
gene id: 662476:KDQ40_RS09040
uniprot id: M0JTT9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS13655
gene id: 662476:KDQ40_RS13655
uniprot id: M0K199
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

662476:KDQ40 RS03750
gene id: 662476:KDQ40_RS03750
uniprot id: M0K453
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

662476:KDQ40 RS04665
gene id: 662476:KDQ40_RS04665
uniprot id: M0JY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

662476:KDQ40 RS11990
gene id: 662476:KDQ40_RS11990
uniprot id: M0JSQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

662476:KDQ40 RS00800
gene id: 662476:KDQ40_RS00800
uniprot id: M0K2B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

662476:KDQ40 RS06275
gene id: 662476:KDQ40_RS06275
uniprot id: M0JXD1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

662476:KDQ40 RS10500
gene id: 662476:KDQ40_RS10500
uniprot id: M0JWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662476:KDQ40 RS04735
gene id: 662476:KDQ40_RS04735
uniprot id: M0JYQ1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS17890
gene id: 662476:KDQ40_RS17890
uniprot id: M0JPH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS02735
gene id: 662476:KDQ40_RS02735
uniprot id: M0K990
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS11560
gene id: 662476:KDQ40_RS11560
uniprot id: M0JUR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS18070
gene id: 662476:KDQ40_RS18070
uniprot id: M0JIL0
names: Similarity
messages: Belongs to the UPF0175 family.

662476:KDQ40 RS07650
gene id: 662476:KDQ40_RS07650
uniprot id: M0JVP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

662476:KDQ40 RS12985
gene id: 662476:KDQ40_RS12985
uniprot id: M0K0V1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

662476:KDQ40 RS13730
gene id: 662476:KDQ40_RS13730
uniprot id: M0JZG5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

662476:KDQ40 RS12045
gene id: 662476:KDQ40_RS12045
uniprot id: M0JUZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

662476:KDQ40 RS12965
gene id: 662476:KDQ40_RS12965
uniprot id: M0JZ37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

662476:KDQ40 RS15785
gene id: 662476:KDQ40_RS15785
uniprot id: M0K2M8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662476:KDQ40 RS10880
gene id: 662476:KDQ40_RS10880
uniprot id: M0JUS2
names: Similarity
messages: Belongs to the thymidylate kinase family.

662476:KDQ40 RS08195
gene id: 662476:KDQ40_RS08195
uniprot id: M0JZP3
names: Similarity
messages: Belongs to the peptidase M24B family.

662476:KDQ40 RS06870
gene id: 662476:KDQ40_RS06870
uniprot id: A0A8T8KEC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08325
gene id: 662476:KDQ40_RS08325
uniprot id: M0JVS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

662476:KDQ40 RS19470
gene id: 662476:KDQ40_RS19470
uniprot id: M0JNI8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS02330
gene id: 662476:KDQ40_RS02330
uniprot id: M0K3M2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

662476:KDQ40 RS21960
gene id: 662476:KDQ40_RS21960
uniprot id: M0JDX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS19295
gene id: 662476:KDQ40_RS19295
uniprot id: M0JNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

662476:KDQ40 RS16500
gene id: 662476:KDQ40_RS16500
uniprot id: M0JQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

662476:KDQ40 RS09390
gene id: 662476:KDQ40_RS09390
uniprot id: M0JUH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

662476:KDQ40 RS10960
gene id: 662476:KDQ40_RS10960
uniprot id: M0JUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662476:KDQ40 RS07300
gene id: 662476:KDQ40_RS07300
uniprot id: M0JXW1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS04425
gene id: 662476:KDQ40_RS04425
uniprot id: M0K1R6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09410
gene id: 662476:KDQ40_RS09410
uniprot id: M0JXB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS10625
gene id: 662476:KDQ40_RS10625
uniprot id: M0JUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

662476:KDQ40 RS09470
gene id: 662476:KDQ40_RS09470
uniprot id: M0JYG4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS09650
gene id: 662476:KDQ40_RS09650
uniprot id: M0JUL2
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS22400
gene id: 662476:KDQ40_RS22400
uniprot id: M0JPD5
names: Similarity
messages: Belongs to the MCM family.

662476:KDQ40 RS06070
gene id: 662476:KDQ40_RS06070
uniprot id: M0JX94
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS17810
gene id: 662476:KDQ40_RS17810
uniprot id: M0JNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

662476:KDQ40 RS07615
gene id: 662476:KDQ40_RS07615
uniprot id: M0K063
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

662476:KDQ40 RS13910
gene id: 662476:KDQ40_RS13910
uniprot id: M0K4Q9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS05865
gene id: 662476:KDQ40_RS05865
uniprot id: M0JWK7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

662476:KDQ40 RS05360
gene id: 662476:KDQ40_RS05360
uniprot id: A0A8T8KDI6
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15115
gene id: 662476:KDQ40_RS15115
uniprot id: M0K5P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

662476:KDQ40 RS08125
gene id: 662476:KDQ40_RS08125
uniprot id: M0JVP0
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

662476:KDQ40 RS11210
gene id: 662476:KDQ40_RS11210
uniprot id: M0JTM3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS10055
gene id: 662476:KDQ40_RS10055
uniprot id: M0JXN8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

662476:KDQ40 RS16625
gene id: 662476:KDQ40_RS16625
uniprot id: A0A8T8KLZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662476:KDQ40 RS20615
gene id: 662476:KDQ40_RS20615
uniprot id: M0JSF7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04305
gene id: 662476:KDQ40_RS04305
uniprot id: M0K2G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS05795
gene id: 662476:KDQ40_RS05795
uniprot id: M0JYI2
names: Similarity
messages: Belongs to the Dps family.

662476:KDQ40 RS03170
gene id: 662476:KDQ40_RS03170
uniprot id: M0K902
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

662476:KDQ40 RS03290
gene id: 662476:KDQ40_RS03290
uniprot id: M0K4F4
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

662476:KDQ40 RS02235
gene id: 662476:KDQ40_RS02235
uniprot id: M0K7L0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

662476:KDQ40 RS10915
gene id: 662476:KDQ40_RS10915
uniprot id: M0JY71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

662476:KDQ40 RS10365
gene id: 662476:KDQ40_RS10365
uniprot id: M0JUG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

662476:KDQ40 RS00485
gene id: 662476:KDQ40_RS00485
uniprot id: M0K648
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS07485
gene id: 662476:KDQ40_RS07485
uniprot id: M0JZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

662476:KDQ40 RS20025
gene id: 662476:KDQ40_RS20025
uniprot id: M0JTS8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS18915
gene id: 662476:KDQ40_RS18915
uniprot id: M0JK92
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

662476:KDQ40 RS21965
gene id: 662476:KDQ40_RS21965
uniprot id: M0JBR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS09845
gene id: 662476:KDQ40_RS09845
uniprot id: M0JWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

662476:KDQ40 RS14070
gene id: 662476:KDQ40_RS14070
uniprot id: M0K3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

662476:KDQ40 RS02005
gene id: 662476:KDQ40_RS02005
uniprot id: M0K3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12205
gene id: 662476:KDQ40_RS12205
uniprot id: M0JV18
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS01905
gene id: 662476:KDQ40_RS01905
uniprot id: M0K500
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

662476:KDQ40 RS16260
gene id: 662476:KDQ40_RS16260
uniprot id: M0JTF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS00020
gene id: 662476:KDQ40_RS00020
uniprot id: M0K5Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

662476:KDQ40 RS09875
gene id: 662476:KDQ40_RS09875
uniprot id: M0JXK1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

662476:KDQ40 RS05720
gene id: 662476:KDQ40_RS05720
uniprot id: M0JYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS02640
gene id: 662476:KDQ40_RS02640
uniprot id: M0K8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

662476:KDQ40 RS04520
gene id: 662476:KDQ40_RS04520
uniprot id: M0JZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS15425
gene id: 662476:KDQ40_RS15425
uniprot id: M0K1K4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08900
gene id: 662476:KDQ40_RS08900
uniprot id: M0JZZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

662476:KDQ40 RS10130
gene id: 662476:KDQ40_RS10130
uniprot id: M0JXQ4
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

662476:KDQ40 RS03760
gene id: 662476:KDQ40_RS03760
uniprot id: M0K8N4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

662476:KDQ40 RS04590
gene id: 662476:KDQ40_RS04590
uniprot id: M0JY68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

662476:KDQ40 RS13650
gene id: 662476:KDQ40_RS13650
uniprot id: M0K362
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

662476:KDQ40 RS01220
gene id: 662476:KDQ40_RS01220
uniprot id: M0K5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

662476:KDQ40 RS11825
gene id: 662476:KDQ40_RS11825
uniprot id: M0JT57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

662476:KDQ40 RS09320
gene id: 662476:KDQ40_RS09320
uniprot id: M0JTY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

662476:KDQ40 RS03795
gene id: 662476:KDQ40_RS03795
uniprot id: M0K5U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS02605
gene id: 662476:KDQ40_RS02605
uniprot id: M0K9B9
names: Similarity
messages: Belongs to the UPF0045 family.

662476:KDQ40 RS06820
gene id: 662476:KDQ40_RS06820
uniprot id: M0JX19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662476:KDQ40 RS01845
gene id: 662476:KDQ40_RS01845
uniprot id: A0A8T8KI19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS10465
gene id: 662476:KDQ40_RS10465
uniprot id: M0JV17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09555
gene id: 662476:KDQ40_RS09555
uniprot id: M0JU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS12165
gene id: 662476:KDQ40_RS12165
uniprot id: M0JST7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

662476:KDQ40 RS17735
gene id: 662476:KDQ40_RS17735
uniprot id: A0A8T8KGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

662476:KDQ40 RS07310
gene id: 662476:KDQ40_RS07310
uniprot id: M0JZ96
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

662476:KDQ40 RS13630
gene id: 662476:KDQ40_RS13630
uniprot id: M0K1A4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS05425
gene id: 662476:KDQ40_RS05425
uniprot id: M0JZW4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS11540
gene id: 662476:KDQ40_RS11540
uniprot id: M0JVX8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

662476:KDQ40 RS11360
gene id: 662476:KDQ40_RS11360
uniprot id: M0JUM7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

662476:KDQ40 RS03365
gene id: 662476:KDQ40_RS03365
uniprot id: M0K4D5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10475
gene id: 662476:KDQ40_RS10475
uniprot id: M0JWQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

662476:KDQ40 RS02405
gene id: 662476:KDQ40_RS02405
uniprot id: M0K3K8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS08475
gene id: 662476:KDQ40_RS08475
uniprot id: M0JVU7
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

662476:KDQ40 RS04865
gene id: 662476:KDQ40_RS04865
uniprot id: M0K237
names: Similarity
messages: Belongs to the GARS family.

662476:KDQ40 RS12920
gene id: 662476:KDQ40_RS12920
uniprot id: M0JZM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

662476:KDQ40 RS03935
gene id: 662476:KDQ40_RS03935
uniprot id: M0K412
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

662476:KDQ40 RS03380
gene id: 662476:KDQ40_RS03380
uniprot id: M0K7Y9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

662476:KDQ40 RS02680
gene id: 662476:KDQ40_RS02680
uniprot id: M0K5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS10345
gene id: 662476:KDQ40_RS10345
uniprot id: M0JWM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

662476:KDQ40 RS16590
gene id: 662476:KDQ40_RS16590
uniprot id: M0JMP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12850
gene id: 662476:KDQ40_RS12850
uniprot id: M0K3K5
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

662476:KDQ40 RS10760
gene id: 662476:KDQ40_RS10760
uniprot id: M0JY40
names: Similarity
messages: Belongs to the cytochrome P450 family.

662476:KDQ40 RS05850
gene id: 662476:KDQ40_RS05850
uniprot id: M0K073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

662476:KDQ40 RS07765
gene id: 662476:KDQ40_RS07765
uniprot id: M0K094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

662476:KDQ40 RS22815
gene id: 662476:KDQ40_RS22815
uniprot id: M0JNV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08785
gene id: 662476:KDQ40_RS08785
uniprot id: M0JVG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662476:KDQ40 RS11690
gene id: 662476:KDQ40_RS11690
uniprot id: M0JW07
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

662476:KDQ40 RS08760
gene id: 662476:KDQ40_RS08760
uniprot id: M0JVF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

662476:KDQ40 RS16600
gene id: 662476:KDQ40_RS16600
uniprot id: M0JKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS11395
gene id: 662476:KDQ40_RS11395
uniprot id: M0JWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

662476:KDQ40 RS01120
gene id: 662476:KDQ40_RS01120
uniprot id: M0K5T4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS00045
gene id: 662476:KDQ40_RS00045
uniprot id: M0K1Z7
names: Similarity
messages: Belongs to the selenium-binding protein family.

662476:KDQ40 RS18175
gene id: 662476:KDQ40_RS18175
uniprot id: M0JHN6
names: Similarity
messages: Belongs to the UPF0175 family.

662476:KDQ40 RS20590
gene id: 662476:KDQ40_RS20590
uniprot id: M0JSF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

662476:KDQ40 RS02630
gene id: 662476:KDQ40_RS02630
uniprot id: M0K5C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

662476:KDQ40 RS05450
gene id: 662476:KDQ40_RS05450
uniprot id: M0JZW9
names: Similarity
messages: Belongs to the HypE family.

662476:KDQ40 RS15165
gene id: 662476:KDQ40_RS15165
uniprot id: M0K129
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

662476:KDQ40 RS22225
gene id: 662476:KDQ40_RS22225
uniprot id: M0JF50
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS15925
gene id: 662476:KDQ40_RS15925
uniprot id: M0K590
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

662476:KDQ40 RS08725
gene id: 662476:KDQ40_RS08725
uniprot id: M0JZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS04505
gene id: 662476:KDQ40_RS04505
uniprot id: M0K2J3
names: Similarity
messages: Belongs to the MoaB/Mog family.

662476:KDQ40 RS00100
gene id: 662476:KDQ40_RS00100
uniprot id: M0K5X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

662476:KDQ40 RS10460
gene id: 662476:KDQ40_RS10460
uniprot id: M0JZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

662476:KDQ40 RS11040
gene id: 662476:KDQ40_RS11040
uniprot id: M0JVD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

662476:KDQ40 RS11830
gene id: 662476:KDQ40_RS11830
uniprot id: M0JSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

662476:KDQ40 RS14280
gene id: 662476:KDQ40_RS14280
uniprot id: M0JZY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

662476:KDQ40 RS19535
gene id: 662476:KDQ40_RS19535
uniprot id: M0JSR6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

662476:KDQ40 RS20115
gene id: 662476:KDQ40_RS20115
uniprot id: M0JRT6
names: Similarity
messages: Belongs to the RutC family.

662476:KDQ40 RS05460
gene id: 662476:KDQ40_RS05460
uniprot id: M0JWV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

662476:KDQ40 RS15705
gene id: 662476:KDQ40_RS15705
uniprot id: M0K4I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

662476:KDQ40 RS15260
gene id: 662476:KDQ40_RS15260
uniprot id: M0K2V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

662476:KDQ40 RS13460
gene id: 662476:KDQ40_RS13460
uniprot id: M0K062
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS00215
gene id: 662476:KDQ40_RS00215
uniprot id: M0K536
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

662476:KDQ40 RS14665
gene id: 662476:KDQ40_RS14665
uniprot id: M0K491
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

662476:KDQ40 RS17025
gene id: 662476:KDQ40_RS17025
uniprot id: M0JLI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS00815
gene id: 662476:KDQ40_RS00815
uniprot id: M0K5Y8
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS15070
gene id: 662476:KDQ40_RS15070
uniprot id: M0K4T5
names: Similarity
messages: Belongs to the SUI1 family.

662476:KDQ40 RS17000
gene id: 662476:KDQ40_RS17000
uniprot id: M0JLJ0
names: Similarity
messages: Belongs to the TPP enzyme family.

662476:KDQ40 RS15170
gene id: 662476:KDQ40_RS15170
uniprot id: M0K1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

662476:KDQ40 RS15195
gene id: 662476:KDQ40_RS15195
uniprot id: M0K1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

662476:KDQ40 RS10360
gene id: 662476:KDQ40_RS10360
uniprot id: M0JV03
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

662476:KDQ40 RS09630
gene id: 662476:KDQ40_RS09630
uniprot id: M0JU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

662476:KDQ40 RS09120
gene id: 662476:KDQ40_RS09120
uniprot id: M0JX64
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

662476:KDQ40 RS11635
gene id: 662476:KDQ40_RS11635
uniprot id: M0JUS6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

662476:KDQ40 RS14640
gene id: 662476:KDQ40_RS14640
uniprot id: M0K498
names: Similarity
messages: Belongs to the HAM1 NTPase family.

662476:KDQ40 RS01820
gene id: 662476:KDQ40_RS01820
uniprot id: M0K7V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

662476:KDQ40 RS00880
gene id: 662476:KDQ40_RS00880
uniprot id: M0K2B1
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS16460
gene id: 662476:KDQ40_RS16460
uniprot id: M0JSB6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

662476:KDQ40 RS14505
gene id: 662476:KDQ40_RS14505
uniprot id: M0JZU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS16945
gene id: 662476:KDQ40_RS16945
uniprot id: M0JMG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS00680
gene id: 662476:KDQ40_RS00680
uniprot id: M0K6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS00940
gene id: 662476:KDQ40_RS00940
uniprot id: M0K6T1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

662476:KDQ40 RS06050
gene id: 662476:KDQ40_RS06050
uniprot id: M0JWN9
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

662476:KDQ40 RS05870
gene id: 662476:KDQ40_RS05870
uniprot id: M0JYJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662476:KDQ40 RS05995
gene id: 662476:KDQ40_RS05995
uniprot id: M0JX82
names: Similarity
messages: Belongs to the glutaredoxin family.

662476:KDQ40 RS09610
gene id: 662476:KDQ40_RS09610
uniprot id: M0JW99
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

662476:KDQ40 RS00395
gene id: 662476:KDQ40_RS00395
uniprot id: M0K2I1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS09060
gene id: 662476:KDQ40_RS09060
uniprot id: M0JUA5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

662476:KDQ40 RS09635
gene id: 662476:KDQ40_RS09635
uniprot id: M0JWA2
names: Caution
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS10585
gene id: 662476:KDQ40_RS10585
uniprot id: M0JZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

662476:KDQ40 RS05025
gene id: 662476:KDQ40_RS05025
uniprot id: A0A8T8KJ66
names: Similarity
messages: Belongs to the cytochrome P450 family.

662476:KDQ40 RS15400
gene id: 662476:KDQ40_RS15400
uniprot id: M0K1K8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

662476:KDQ40 RS04800
gene id: 662476:KDQ40_RS04800
uniprot id: M0JXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

662476:KDQ40 RS10890
gene id: 662476:KDQ40_RS10890
uniprot id: M0JY65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

662476:KDQ40 RS11465
gene id: 662476:KDQ40_RS11465
uniprot id: M0JVW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS06370
gene id: 662476:KDQ40_RS06370
uniprot id: M0K1A2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

662476:KDQ40 RS06260
gene id: 662476:KDQ40_RS06260
uniprot id: M0JYR2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

662476:KDQ40 RS06490
gene id: 662476:KDQ40_RS06490
uniprot id: M0K0J3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

662476:KDQ40 RS08860
gene id: 662476:KDQ40_RS08860
uniprot id: A0A8T8K7H1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS06830
gene id: 662476:KDQ40_RS06830
uniprot id: M0K0P9
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS00010
gene id: 662476:KDQ40_RS00010
uniprot id: M0K1D2
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19300
gene id: 662476:KDQ40_RS19300
uniprot id: M0JQM7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

662476:KDQ40 RS07045
gene id: 662476:KDQ40_RS07045
uniprot id: A0A8T8KK70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS07565
gene id: 662476:KDQ40_RS07565
uniprot id: M0K151
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

662476:KDQ40 RS08290
gene id: 662476:KDQ40_RS08290
uniprot id: M0JYP8
names: Similarity
messages: Belongs to the UPF0173 family.

662476:KDQ40 RS00210
gene id: 662476:KDQ40_RS00210
uniprot id: M0K620
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12630
gene id: 662476:KDQ40_RS12630
uniprot id: M0K2R7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

662476:KDQ40 RS11555
gene id: 662476:KDQ40_RS11555
uniprot id: M0JSI4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS14440
gene id: 662476:KDQ40_RS14440
uniprot id: M0K4E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS14075
gene id: 662476:KDQ40_RS14075
uniprot id: M0K1X6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS19620
gene id: 662476:KDQ40_RS19620
uniprot id: M0JNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS08500
gene id: 662476:KDQ40_RS08500
uniprot id: M0JVV1
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

662476:KDQ40 RS00480
gene id: 662476:KDQ40_RS00480
uniprot id: M0K712
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS14555
gene id: 662476:KDQ40_RS14555
uniprot id: M0JZT9
names: Similarity
messages: Belongs to the citrate synthase family.

662476:KDQ40 RS01895
gene id: 662476:KDQ40_RS01895
uniprot id: M0K7T7
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS19970
gene id: 662476:KDQ40_RS19970
uniprot id: M0JSY7
names: Similarity
messages: Belongs to the hemerythrin family.

662476:KDQ40 RS07215
gene id: 662476:KDQ40_RS07215
uniprot id: M0K0X3
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS02055
gene id: 662476:KDQ40_RS02055
uniprot id: M0K7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

662476:KDQ40 RS02165
gene id: 662476:KDQ40_RS02165
uniprot id: M0K4U8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

662476:KDQ40 RS02635
gene id: 662476:KDQ40_RS02635
uniprot id: M0K9B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

662476:KDQ40 RS16980
gene id: 662476:KDQ40_RS16980
uniprot id: M0JKJ3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

662476:KDQ40 RS20450
gene id: 662476:KDQ40_RS20450
uniprot id: M0JPU4
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

662476:KDQ40 RS02155
gene id: 662476:KDQ40_RS02155
uniprot id: M0K7M7
names: Similarity
messages: Belongs to the Ahb/Nir family.

662476:KDQ40 RS09110
gene id: 662476:KDQ40_RS09110
uniprot id: M0JTV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662476:KDQ40 RS22000
gene id: 662476:KDQ40_RS22000
uniprot id: A0A8T8KM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS02995
gene id: 662476:KDQ40_RS02995
uniprot id: M0K556
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
messages: Tetramer of two components I and two components II.

662476:KDQ40 RS11620
gene id: 662476:KDQ40_RS11620
uniprot id: M0JWW4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

662476:KDQ40 RS09220
gene id: 662476:KDQ40_RS09220
uniprot id: M0JTW8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

662476:KDQ40 RS21900
gene id: 662476:KDQ40_RS21900
uniprot id: M0JDS3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS12530
gene id: 662476:KDQ40_RS12530
uniprot id: M0K2T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

662476:KDQ40 RS21425
gene id: 662476:KDQ40_RS21425
uniprot id: M0JE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

662476:KDQ40 RS19105
gene id: 662476:KDQ40_RS19105
uniprot id: M0JIG7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

662476:KDQ40 RS12955
gene id: 662476:KDQ40_RS12955
uniprot id: M0K2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

662476:KDQ40 RS16640
gene id: 662476:KDQ40_RS16640
uniprot id: M0JMN4
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS04430
gene id: 662476:KDQ40_RS04430
uniprot id: M0K2I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

662476:KDQ40 RS03755
gene id: 662476:KDQ40_RS03755
uniprot id: M0K4S8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

662476:KDQ40 RS11525
gene id: 662476:KDQ40_RS11525
uniprot id: M0JT03
names: Similarity
messages: Belongs to the PDCD5 family.

662476:KDQ40 RS02355
gene id: 662476:KDQ40_RS02355
uniprot id: M0K3L7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

662476:KDQ40 RS11745
gene id: 662476:KDQ40_RS11745
uniprot id: M0JWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

662476:KDQ40 RS17750
gene id: 662476:KDQ40_RS17750
uniprot id: M0JPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS12155
gene id: 662476:KDQ40_RS12155
uniprot id: M0JX62
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS13020
gene id: 662476:KDQ40_RS13020
uniprot id: M0K3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662476:KDQ40 RS23075
gene id: 662476:KDQ40_RS23075
uniprot id: M0JKE5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS07305
gene id: 662476:KDQ40_RS07305
uniprot id: M0JXC8
names: Caution
names: Similarity
messages: Belongs to the arginase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS07385
gene id: 662476:KDQ40_RS07385
uniprot id: M0JXE9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

662476:KDQ40 RS12555
gene id: 662476:KDQ40_RS12555
uniprot id: M0K2T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

662476:KDQ40 RS07545
gene id: 662476:KDQ40_RS07545
uniprot id: M0K1Y4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

662476:KDQ40 RS14980
gene id: 662476:KDQ40_RS14980
uniprot id: M0K160
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS21240
gene id: 662476:KDQ40_RS21240
uniprot id: M0JFY5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

662476:KDQ40 RS05935
gene id: 662476:KDQ40_RS05935
uniprot id: M0K087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

662476:KDQ40 RS02665
gene id: 662476:KDQ40_RS02665
uniprot id: M0K8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

662476:KDQ40 RS11655
gene id: 662476:KDQ40_RS11655
uniprot id: M0JSK1
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10565
gene id: 662476:KDQ40_RS10565
uniprot id: M0JV33
names: Subcellular Location Annotation
messages: Cytoplasm

662476:KDQ40 RS15505
gene id: 662476:KDQ40_RS15505
uniprot id: M0K1J4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS02195
gene id: 662476:KDQ40_RS02195
uniprot id: M0K302
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

662476:KDQ40 RS04610
gene id: 662476:KDQ40_RS04610
uniprot id: M0JYM4
names: Similarity
messages: Belongs to the UPF0212 family.

662476:KDQ40 RS06575
gene id: 662476:KDQ40_RS06575
uniprot id: M0K1D5
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10830
gene id: 662476:KDQ40_RS10830
uniprot id: M0JWX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS08580
gene id: 662476:KDQ40_RS08580
uniprot id: M0JVW5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

662476:KDQ40 RS20440
gene id: 662476:KDQ40_RS20440
uniprot id: M0JU16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS10705
gene id: 662476:KDQ40_RS10705
uniprot id: M0JY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

662476:KDQ40 RS01865
gene id: 662476:KDQ40_RS01865
uniprot id: M0K3X2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS11605
gene id: 662476:KDQ40_RS11605
uniprot id: M0JSJ3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

662476:KDQ40 RS18975
gene id: 662476:KDQ40_RS18975
uniprot id: M0JM40
names: Subcellular Location Annotation
messages: Membrane

662476:KDQ40 RS10060
gene id: 662476:KDQ40_RS10060
uniprot id: M0JYT4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662476:KDQ40 RS09350
gene id: 662476:KDQ40_RS09350
uniprot id: M0JW58
names: Similarity
messages: Belongs to the cytochrome P450 family.

662476:KDQ40 RS14105
gene id: 662476:KDQ40_RS14105
uniprot id: M0K021
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

662476:KDQ40 RS10985
gene id: 662476:KDQ40_RS10985
uniprot id: M0JUU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

662476:KDQ40 RS20720
gene id: 662476:KDQ40_RS20720
uniprot id: M0JNQ1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

662476:KDQ40 RS11855
gene id: 662476:KDQ40_RS11855
uniprot id: M0JSN6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

662476:KDQ40 RS03060
gene id: 662476:KDQ40_RS03060
uniprot id: M0K696
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662476:KDQ40 RS01650
gene id: 662476:KDQ40_RS01650
uniprot id: A0A8T8KHG9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

662476:KDQ40 RS14345
gene id: 662476:KDQ40_RS14345
uniprot id: M0K3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

662476:KDQ40 RS04030
gene id: 662476:KDQ40_RS04030
uniprot id: M0KAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

662476:KDQ40 RS01235
gene id: 662476:KDQ40_RS01235
uniprot id: M0K2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

662476:KDQ40 RS02215
gene id: 662476:KDQ40_RS02215
uniprot id: M0K4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane