649349:LBYS RS08880
gene id: 649349:LBYS_RS08880
uniprot id: E4RQN6
names: Similarity
messages: Belongs to the arginase family.

649349:LBYS RS04525
gene id: 649349:LBYS_RS04525
uniprot id: E4RRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

649349:LBYS RS11735
gene id: 649349:LBYS_RS11735
uniprot id: E4RWG0
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS12615
gene id: 649349:LBYS_RS12615
uniprot id: E4RYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS06570
gene id: 649349:LBYS_RS06570
uniprot id: E4RVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

649349:LBYS RS07850
gene id: 649349:LBYS_RS07850
uniprot id: E4RY73
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

649349:LBYS RS06985
gene id: 649349:LBYS_RS06985
uniprot id: E4RW84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

649349:LBYS RS08885
gene id: 649349:LBYS_RS08885
uniprot id: E4RQN7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

649349:LBYS RS00445
gene id: 649349:LBYS_RS00445
uniprot id: E4RSN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

649349:LBYS RS11510
gene id: 649349:LBYS_RS11510
uniprot id: E4RWB5
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS07960
gene id: 649349:LBYS_RS07960
uniprot id: E4RY95
names: Similarity
messages: Belongs to the SAICAR synthetase family.

649349:LBYS RS15175
gene id: 649349:LBYS_RS15175
uniprot id: E4RTZ1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

649349:LBYS RS01365
gene id: 649349:LBYS_RS01365
uniprot id: E4RUR2
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS15770
gene id: 649349:LBYS_RS15770
uniprot id: E4RV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS02490
gene id: 649349:LBYS_RS02490
uniprot id: E4RXC8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS17510
gene id: 649349:LBYS_RS17510
uniprot id: E4RZ36
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS16600
gene id: 649349:LBYS_RS16600
uniprot id: E4RX58
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS15955
gene id: 649349:LBYS_RS15955
uniprot id: E4RVU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

649349:LBYS RS08205
gene id: 649349:LBYS_RS08205
uniprot id: E4RYV7
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

649349:LBYS RS17910
gene id: 649349:LBYS_RS17910
uniprot id: E4RZU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

649349:LBYS RS13400
gene id: 649349:LBYS_RS13400
uniprot id: E4RQE2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS13210
gene id: 649349:LBYS_RS13210
uniprot id: E4RZR9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

649349:LBYS RS10500
gene id: 649349:LBYS_RS10500
uniprot id: E4RTT7
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS11220
gene id: 649349:LBYS_RS11220
uniprot id: E4RVN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

649349:LBYS RS03725
gene id: 649349:LBYS_RS03725
uniprot id: E4RQ30
names: Similarity
messages: Belongs to the NusB family.

649349:LBYS RS10370
gene id: 649349:LBYS_RS10370
uniprot id: E4RTR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

649349:LBYS RS11185
gene id: 649349:LBYS_RS11185
uniprot id: E4RV44
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS04785
gene id: 649349:LBYS_RS04785
uniprot id: E4RRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

649349:LBYS RS16045
gene id: 649349:LBYS_RS16045
uniprot id: E4RVW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

649349:LBYS RS03245
gene id: 649349:LBYS_RS03245
uniprot id: E4RYQ7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

649349:LBYS RS11405
gene id: 649349:LBYS_RS11405
uniprot id: E4RVS0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS17130
gene id: 649349:LBYS_RS17130
uniprot id: E4RXY1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

649349:LBYS RS09705
gene id: 649349:LBYS_RS09705
uniprot id: E4RRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

649349:LBYS RS06840
gene id: 649349:LBYS_RS06840
uniprot id: E4RW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

649349:LBYS RS11605
gene id: 649349:LBYS_RS11605
uniprot id: E4RWD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

649349:LBYS RS10305
gene id: 649349:LBYS_RS10305
uniprot id: E4RTP7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

649349:LBYS RS01785
gene id: 649349:LBYS_RS01785
uniprot id: E4RVF2
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS08245
gene id: 649349:LBYS_RS08245
uniprot id: E4RYW6
names: Similarity
messages: Belongs to the DprA/Smf family.

649349:LBYS RS09095
gene id: 649349:LBYS_RS09095
uniprot id: E4RQS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS01165
gene id: 649349:LBYS_RS01165
uniprot id: E4RU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS17020
gene id: 649349:LBYS_RS17020
uniprot id: E4RXW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS08115
gene id: 649349:LBYS_RS08115
uniprot id: E4RYT8
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS14655
gene id: 649349:LBYS_RS14655
uniprot id: E4RSM5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

649349:LBYS RS08410
gene id: 649349:LBYS_RS08410
uniprot id: E4RZH2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

649349:LBYS RS06555
gene id: 649349:LBYS_RS06555
uniprot id: E4RVH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS08735
gene id: 649349:LBYS_RS08735
uniprot id: E4RQ88
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

649349:LBYS RS06560
gene id: 649349:LBYS_RS06560
uniprot id: E4RVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS17315
gene id: 649349:LBYS_RS17315
uniprot id: E4RYI4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

649349:LBYS RS04970
gene id: 649349:LBYS_RS04970
uniprot id: E4RS83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

649349:LBYS RS00325
gene id: 649349:LBYS_RS00325
uniprot id: E4RS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

649349:LBYS RS11910
gene id: 649349:LBYS_RS11910
uniprot id: E4RX27
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

649349:LBYS RS17070
gene id: 649349:LBYS_RS17070
uniprot id: E4RXW9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

649349:LBYS RS05060
gene id: 649349:LBYS_RS05060
uniprot id: E4RSA1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

649349:LBYS RS08480
gene id: 649349:LBYS_RS08480
uniprot id: E4RZI7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

649349:LBYS RS07830
gene id: 649349:LBYS_RS07830
uniprot id: E4RY69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

649349:LBYS RS12805
gene id: 649349:LBYS_RS12805
uniprot id: E4RZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS08315
gene id: 649349:LBYS_RS08315
uniprot id: E4RZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

649349:LBYS RS07875
gene id: 649349:LBYS_RS07875
uniprot id: E4RY78
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS08870
gene id: 649349:LBYS_RS08870
uniprot id: E4RQN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10450
gene id: 649349:LBYS_RS10450
uniprot id: E4RTS7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS00270
gene id: 649349:LBYS_RS00270
uniprot id: E4RS32
names: Similarity
messages: Belongs to the ABC transporter superfamily.

649349:LBYS RS14445
gene id: 649349:LBYS_RS14445
uniprot id: E4RSI1
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

649349:LBYS RS03450
gene id: 649349:LBYS_RS03450
uniprot id: E4RZC2
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

649349:LBYS RS11615
gene id: 649349:LBYS_RS11615
uniprot id: E4RWD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS09065
gene id: 649349:LBYS_RS09065
uniprot id: E4RQS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS14850
gene id: 649349:LBYS_RS14850
uniprot id: E4RT96
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

649349:LBYS RS04980
gene id: 649349:LBYS_RS04980
uniprot id: E4RS85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

649349:LBYS RS17325
gene id: 649349:LBYS_RS17325
uniprot id: E4RYI6
names: Similarity
messages: Belongs to the peptidase U62 family.

649349:LBYS RS08990
gene id: 649349:LBYS_RS08990
uniprot id: E4RQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

649349:LBYS RS02240
gene id: 649349:LBYS_RS02240
uniprot id: E4RWQ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

649349:LBYS RS15435
gene id: 649349:LBYS_RS15435
uniprot id: E4RUL2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

649349:LBYS RS03130
gene id: 649349:LBYS_RS03130
uniprot id: E4RYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS08295
gene id: 649349:LBYS_RS08295
uniprot id: E4RYX5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

649349:LBYS RS08680
gene id: 649349:LBYS_RS08680
uniprot id: E4RQ77
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

649349:LBYS RS08405
gene id: 649349:LBYS_RS08405
uniprot id: E4RZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

649349:LBYS RS16650
gene id: 649349:LBYS_RS16650
uniprot id: E4RX66
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

649349:LBYS RS06950
gene id: 649349:LBYS_RS06950
uniprot id: E4RW77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

649349:LBYS RS09720
gene id: 649349:LBYS_RS09720
uniprot id: E4RSC1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

649349:LBYS RS08375
gene id: 649349:LBYS_RS08375
uniprot id: E4RZG4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

649349:LBYS RS12360
gene id: 649349:LBYS_RS12360
uniprot id: E4RYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS03190
gene id: 649349:LBYS_RS03190
uniprot id: E4RYP6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09595
gene id: 649349:LBYS_RS09595
uniprot id: E4RRU6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

649349:LBYS RS13155
gene id: 649349:LBYS_RS13155
uniprot id: E4RZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

649349:LBYS RS15865
gene id: 649349:LBYS_RS15865
uniprot id: E4RV95
names: Similarity
messages: Belongs to the Skp family.

649349:LBYS RS10110
gene id: 649349:LBYS_RS10110
uniprot id: E4RT23
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10275
gene id: 649349:LBYS_RS10275
uniprot id: E4RT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

649349:LBYS RS13235
gene id: 649349:LBYS_RS13235
uniprot id: E4RQA9
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17170
gene id: 649349:LBYS_RS17170
uniprot id: E4RXY9
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS06105
gene id: 649349:LBYS_RS06105
uniprot id: E4RUB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS17210
gene id: 649349:LBYS_RS17210
uniprot id: E4RYG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10070
gene id: 649349:LBYS_RS10070
uniprot id: E4RT14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

649349:LBYS RS13360
gene id: 649349:LBYS_RS13360
uniprot id: E4RQD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

649349:LBYS RS15010
gene id: 649349:LBYS_RS15010
uniprot id: E4RTV8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

649349:LBYS RS17025
gene id: 649349:LBYS_RS17025
uniprot id: E4RXW2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

649349:LBYS RS14865
gene id: 649349:LBYS_RS14865
uniprot id: E4RT99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

649349:LBYS RS07985
gene id: 649349:LBYS_RS07985
uniprot id: E4RYA0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

649349:LBYS RS08835
gene id: 649349:LBYS_RS08835
uniprot id: E4RQA8
names: Similarity
messages: Belongs to the proline racemase family.

649349:LBYS RS02610
gene id: 649349:LBYS_RS02610
uniprot id: E4RXF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10910
gene id: 649349:LBYS_RS10910
uniprot id: E4RV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

649349:LBYS RS00370
gene id: 649349:LBYS_RS00370
uniprot id: E4RS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

649349:LBYS RS07990
gene id: 649349:LBYS_RS07990
uniprot id: E4RYA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS09920
gene id: 649349:LBYS_RS09920
uniprot id: E4RSF6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS15395
gene id: 649349:LBYS_RS15395
uniprot id: E4RUK4
names: Similarity
messages: Belongs to the UPF0102 family.

649349:LBYS RS09395
gene id: 649349:LBYS_RS09395
uniprot id: E4RRA7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS05890
gene id: 649349:LBYS_RS05890
uniprot id: E4RU72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

649349:LBYS RS02230
gene id: 649349:LBYS_RS02230
uniprot id: E4RWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

649349:LBYS RS11300
gene id: 649349:LBYS_RS11300
uniprot id: E4RVP8
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS11330
gene id: 649349:LBYS_RS11330
uniprot id: E4RVQ4
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

649349:LBYS RS03035
gene id: 649349:LBYS_RS03035
uniprot id: E4RY49
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

649349:LBYS RS05895
gene id: 649349:LBYS_RS05895
uniprot id: E4RU73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

649349:LBYS RS12450
gene id: 649349:LBYS_RS12450
uniprot id: E4RYC9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS10010
gene id: 649349:LBYS_RS10010
uniprot id: E4RT02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

649349:LBYS RS09150
gene id: 649349:LBYS_RS09150
uniprot id: E4RR61
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03885
gene id: 649349:LBYS_RS03885
uniprot id: E4RQH6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS06365
gene id: 649349:LBYS_RS06365
uniprot id: E4RUX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS09600
gene id: 649349:LBYS_RS09600
uniprot id: E4RRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS01645
gene id: 649349:LBYS_RS01645
uniprot id: E4RVC6
names: Cofactor
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

649349:LBYS RS09745
gene id: 649349:LBYS_RS09745
uniprot id: E4RSC6
names: Similarity
messages: Belongs to the peptidase S9C family.

649349:LBYS RS16105
gene id: 649349:LBYS_RS16105
uniprot id: E4RVX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS08215
gene id: 649349:LBYS_RS08215
uniprot id: E4RYV9
names: Similarity
messages: Belongs to the peptidase M16 family.

649349:LBYS RS08330
gene id: 649349:LBYS_RS08330
uniprot id: E4RZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

649349:LBYS RS04965
gene id: 649349:LBYS_RS04965
uniprot id: E4RS82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

649349:LBYS RS06415
gene id: 649349:LBYS_RS06415
uniprot id: E4RUY8
names: Subcellular Location Annotation
messages: Cell inner membrane

649349:LBYS RS03135
gene id: 649349:LBYS_RS03135
uniprot id: E4RYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

649349:LBYS RS14165
gene id: 649349:LBYS_RS14165
uniprot id: E4RRG5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS02825
gene id: 649349:LBYS_RS02825
uniprot id: E4RY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

649349:LBYS RS13445
gene id: 649349:LBYS_RS13445
uniprot id: E4RQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

649349:LBYS RS17975
gene id: 649349:LBYS_RS17975
uniprot id: E4RZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

649349:LBYS RS13200
gene id: 649349:LBYS_RS13200
uniprot id: E4RZR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS02220
gene id: 649349:LBYS_RS02220
uniprot id: E4RWQ5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS08050
gene id: 649349:LBYS_RS08050
uniprot id: E4RYS6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11795
gene id: 649349:LBYS_RS11795
uniprot id: E4RX06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

649349:LBYS RS06145
gene id: 649349:LBYS_RS06145
uniprot id: E4RUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS01030
gene id: 649349:LBYS_RS01030
uniprot id: E4RU24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00905
gene id: 649349:LBYS_RS00905
uniprot id: E4RTG5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

649349:LBYS RS04990
gene id: 649349:LBYS_RS04990
uniprot id: E4RS87
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

649349:LBYS RS16295
gene id: 649349:LBYS_RS16295
uniprot id: E4RWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

649349:LBYS RS14490
gene id: 649349:LBYS_RS14490
uniprot id: E4RSJ1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

649349:LBYS RS15355
gene id: 649349:LBYS_RS15355
uniprot id: E4RUJ7
names: Similarity
messages: Belongs to the Skp family.

649349:LBYS RS07105
gene id: 649349:LBYS_RS07105
uniprot id: E4RWA8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS10115
gene id: 649349:LBYS_RS10115
uniprot id: E4RT24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS16540
gene id: 649349:LBYS_RS16540
uniprot id: E4RWM3
names: Similarity
messages: Belongs to the glutamate synthase family.

649349:LBYS RS06420
gene id: 649349:LBYS_RS06420
uniprot id: E4RUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

649349:LBYS RS14540
gene id: 649349:LBYS_RS14540
uniprot id: E4RSK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS09490
gene id: 649349:LBYS_RS09490
uniprot id: E4RRS5
names: Similarity
messages: Belongs to the universal stress protein A family.

649349:LBYS RS00140
gene id: 649349:LBYS_RS00140
uniprot id: E4RRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

649349:LBYS RS13645
gene id: 649349:LBYS_RS13645
uniprot id: E4RQV5
names: Similarity
messages: Belongs to the ComB family.

649349:LBYS RS08395
gene id: 649349:LBYS_RS08395
uniprot id: E4RZG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

649349:LBYS RS13030
gene id: 649349:LBYS_RS13030
uniprot id: E4RZN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

649349:LBYS RS15585
gene id: 649349:LBYS_RS15585
uniprot id: E4RUP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

649349:LBYS RS08875
gene id: 649349:LBYS_RS08875
uniprot id: E4RQN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

649349:LBYS RS15250
gene id: 649349:LBYS_RS15250
uniprot id: E4RU05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

649349:LBYS RS04625
gene id: 649349:LBYS_RS04625
uniprot id: E4RRL9
names: Similarity
messages: Belongs to the ParB family.

649349:LBYS RS07930
gene id: 649349:LBYS_RS07930
uniprot id: E4RY89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

649349:LBYS RS07250
gene id: 649349:LBYS_RS07250
uniprot id: E4RWW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS13470
gene id: 649349:LBYS_RS13470
uniprot id: E4RQF5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

649349:LBYS RS11590
gene id: 649349:LBYS_RS11590
uniprot id: E4RWD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

649349:LBYS RS04175
gene id: 649349:LBYS_RS04175
uniprot id: E4RQM5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

649349:LBYS RS13635
gene id: 649349:LBYS_RS13635
uniprot id: E4RQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS13135
gene id: 649349:LBYS_RS13135
uniprot id: E4RZQ2
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS07160
gene id: 649349:LBYS_RS07160
uniprot id: E4RWU6
names: Similarity
messages: Belongs to the SCO1/2 family.

649349:LBYS RS07555
gene id: 649349:LBYS_RS07555
uniprot id: E4RXJ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS01775
gene id: 649349:LBYS_RS01775
uniprot id: E4RVF0
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS03025
gene id: 649349:LBYS_RS03025
uniprot id: E4RY47
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

649349:LBYS RS04300
gene id: 649349:LBYS_RS04300
uniprot id: E4RR21
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS16315
gene id: 649349:LBYS_RS16315
uniprot id: E4RWI4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

649349:LBYS RS14505
gene id: 649349:LBYS_RS14505
uniprot id: E4RSJ4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17260
gene id: 649349:LBYS_RS17260
uniprot id: E4RYH3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS13040
gene id: 649349:LBYS_RS13040
uniprot id: E4RZN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

649349:LBYS RS03325
gene id: 649349:LBYS_RS03325
uniprot id: E4RYS3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

649349:LBYS RS06410
gene id: 649349:LBYS_RS06410
uniprot id: E4RUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

649349:LBYS RS03175
gene id: 649349:LBYS_RS03175
uniprot id: E4RYP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS07775
gene id: 649349:LBYS_RS07775
uniprot id: E4RY58
names: Similarity
messages: Belongs to the EPSP synthase family.

649349:LBYS RS14370
gene id: 649349:LBYS_RS14370
uniprot id: E4RS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

649349:LBYS RS14045
gene id: 649349:LBYS_RS14045
uniprot id: E4RRE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

649349:LBYS RS18020
gene id: 649349:LBYS_RS18020
uniprot id: E4RZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

649349:LBYS RS10130
gene id: 649349:LBYS_RS10130
uniprot id: E4RT27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

649349:LBYS RS17850
gene id: 649349:LBYS_RS17850
uniprot id: E4RZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

649349:LBYS RS08235
gene id: 649349:LBYS_RS08235
uniprot id: E4RYW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

649349:LBYS RS14730
gene id: 649349:LBYS_RS14730
uniprot id: E4RT72
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS02965
gene id: 649349:LBYS_RS02965
uniprot id: E4RY35
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS02340
gene id: 649349:LBYS_RS02340
uniprot id: E4RWS4
names: Similarity
messages: Belongs to the peptidase M1 family.

649349:LBYS RS07945
gene id: 649349:LBYS_RS07945
uniprot id: E4RY92
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

649349:LBYS RS13950
gene id: 649349:LBYS_RS13950
uniprot id: E4RRC6
names: Similarity
messages: Belongs to the Fur family.

649349:LBYS RS08005
gene id: 649349:LBYS_RS08005
uniprot id: E4RYA4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09085
gene id: 649349:LBYS_RS09085
uniprot id: E4RQS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

649349:LBYS RS13345
gene id: 649349:LBYS_RS13345
uniprot id: E4RQD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS17255
gene id: 649349:LBYS_RS17255
uniprot id: E4RYH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

649349:LBYS RS01205
gene id: 649349:LBYS_RS01205
uniprot id: E4RU58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

649349:LBYS RS14920
gene id: 649349:LBYS_RS14920
uniprot id: E4RTB0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS05460
gene id: 649349:LBYS_RS05460
uniprot id: E4RSY4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS02390
gene id: 649349:LBYS_RS02390
uniprot id: E4RWT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS07000
gene id: 649349:LBYS_RS07000
uniprot id: E4RW87
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

649349:LBYS RS07475
gene id: 649349:LBYS_RS07475
uniprot id: E4RXH9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

649349:LBYS RS12495
gene id: 649349:LBYS_RS12495
uniprot id: E4RYD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS10350
gene id: 649349:LBYS_RS10350
uniprot id: E4RTQ7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS01770
gene id: 649349:LBYS_RS01770
uniprot id: E4RVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS06620
gene id: 649349:LBYS_RS06620
uniprot id: E4RVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

649349:LBYS RS12265
gene id: 649349:LBYS_RS12265
uniprot id: E4RXR5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS06125
gene id: 649349:LBYS_RS06125
uniprot id: E4RUC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

649349:LBYS RS09050
gene id: 649349:LBYS_RS09050
uniprot id: E4RQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

649349:LBYS RS06440
gene id: 649349:LBYS_RS06440
uniprot id: E4RUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

649349:LBYS RS13885
gene id: 649349:LBYS_RS13885
uniprot id: E4RRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS10230
gene id: 649349:LBYS_RS10230
uniprot id: E4RT48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

649349:LBYS RS10345
gene id: 649349:LBYS_RS10345
uniprot id: E4RTQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS14125
gene id: 649349:LBYS_RS14125
uniprot id: E4RRF7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

649349:LBYS RS17430
gene id: 649349:LBYS_RS17430
uniprot id: E4RYK8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

649349:LBYS RS11470
gene id: 649349:LBYS_RS11470
uniprot id: E4RVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS06510
gene id: 649349:LBYS_RS06510
uniprot id: E4RVG7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

649349:LBYS RS06020
gene id: 649349:LBYS_RS06020
uniprot id: E4RU98
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11785
gene id: 649349:LBYS_RS11785
uniprot id: E4RX04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

649349:LBYS RS17250
gene id: 649349:LBYS_RS17250
uniprot id: E4RYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

649349:LBYS RS17615
gene id: 649349:LBYS_RS17615
uniprot id: E4RZ57
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS16110
gene id: 649349:LBYS_RS16110
uniprot id: E4RVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS03625
gene id: 649349:LBYS_RS03625
uniprot id: E4RQ10
names: Subunit
messages: Homodimer.

649349:LBYS RS04185
gene id: 649349:LBYS_RS04185
uniprot id: E4RQM7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

649349:LBYS RS16065
gene id: 649349:LBYS_RS16065
uniprot id: E4RVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

649349:LBYS RS10280
gene id: 649349:LBYS_RS10280
uniprot id: E4RT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

649349:LBYS RS14745
gene id: 649349:LBYS_RS14745
uniprot id: E4RT75
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS13035
gene id: 649349:LBYS_RS13035
uniprot id: E4RZN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

649349:LBYS RS10820
gene id: 649349:LBYS_RS10820
uniprot id: E4RUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

649349:LBYS RS08800
gene id: 649349:LBYS_RS08800
uniprot id: E4RQA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS09975
gene id: 649349:LBYS_RS09975
uniprot id: E4RSG7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

649349:LBYS RS17955
gene id: 649349:LBYS_RS17955
uniprot id: E4RZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

649349:LBYS RS12855
gene id: 649349:LBYS_RS12855
uniprot id: E4RZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

649349:LBYS RS07315
gene id: 649349:LBYS_RS07315
uniprot id: E4RWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

649349:LBYS RS06350
gene id: 649349:LBYS_RS06350
uniprot id: E4RUX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

649349:LBYS RS01805
gene id: 649349:LBYS_RS01805
uniprot id: E4RVF6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

649349:LBYS RS04375
gene id: 649349:LBYS_RS04375
uniprot id: E4RR36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS16755
gene id: 649349:LBYS_RS16755
uniprot id: E4RX87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

649349:LBYS RS02765
gene id: 649349:LBYS_RS02765
uniprot id: E4RXZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS04170
gene id: 649349:LBYS_RS04170
uniprot id: E4RQM4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

649349:LBYS RS06575
gene id: 649349:LBYS_RS06575
uniprot id: E4RVI0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

649349:LBYS RS06615
gene id: 649349:LBYS_RS06615
uniprot id: E4RVI8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

649349:LBYS RS12520
gene id: 649349:LBYS_RS12520
uniprot id: E4RYD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

649349:LBYS RS01895
gene id: 649349:LBYS_RS01895
uniprot id: E4RW17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

649349:LBYS RS10040
gene id: 649349:LBYS_RS10040
uniprot id: E4RT08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS13870
gene id: 649349:LBYS_RS13870
uniprot id: E4RRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

649349:LBYS RS16210
gene id: 649349:LBYS_RS16210
uniprot id: E4RVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS11385
gene id: 649349:LBYS_RS11385
uniprot id: E4RVR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

649349:LBYS RS07050
gene id: 649349:LBYS_RS07050
uniprot id: E4RW97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

649349:LBYS RS15050
gene id: 649349:LBYS_RS15050
uniprot id: E4RTW6
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS02200
gene id: 649349:LBYS_RS02200
uniprot id: E4RWQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

649349:LBYS RS06155
gene id: 649349:LBYS_RS06155
uniprot id: E4RUC6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS09020
gene id: 649349:LBYS_RS09020
uniprot id: E4RQR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

649349:LBYS RS09885
gene id: 649349:LBYS_RS09885
uniprot id: E4RSE9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

649349:LBYS RS13715
gene id: 649349:LBYS_RS13715
uniprot id: E4RQW9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

649349:LBYS RS09695
gene id: 649349:LBYS_RS09695
uniprot id: E4RRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

649349:LBYS RS13350
gene id: 649349:LBYS_RS13350
uniprot id: E4RQD2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

649349:LBYS RS08065
gene id: 649349:LBYS_RS08065
uniprot id: E4RYS9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

649349:LBYS RS03470
gene id: 649349:LBYS_RS03470
uniprot id: E4RZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS14285
gene id: 649349:LBYS_RS14285
uniprot id: E4RRY8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17535
gene id: 649349:LBYS_RS17535
uniprot id: E4RZ41
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09590
gene id: 649349:LBYS_RS09590
uniprot id: E4RRU5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11670
gene id: 649349:LBYS_RS11670
uniprot id: E4RWE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

649349:LBYS RS06010
gene id: 649349:LBYS_RS06010
uniprot id: E4RU96
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09700
gene id: 649349:LBYS_RS09700
uniprot id: E4RRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

649349:LBYS RS08225
gene id: 649349:LBYS_RS08225
uniprot id: E4RYW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS12490
gene id: 649349:LBYS_RS12490
uniprot id: E4RYD2
names: Similarity
messages: Belongs to the aldose epimerase family.

649349:LBYS RS07135
gene id: 649349:LBYS_RS07135
uniprot id: E4RWU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10090
gene id: 649349:LBYS_RS10090
uniprot id: E4RT18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS16230
gene id: 649349:LBYS_RS16230
uniprot id: E4RVZ7
names: Similarity
messages: Belongs to the AHA1 family.

649349:LBYS RS15720
gene id: 649349:LBYS_RS15720
uniprot id: E4RV66
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

649349:LBYS RS02910
gene id: 649349:LBYS_RS02910
uniprot id: E4RY24
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

649349:LBYS RS13190
gene id: 649349:LBYS_RS13190
uniprot id: E4RZR4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

649349:LBYS RS15085
gene id: 649349:LBYS_RS15085
uniprot id: E4RTX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

649349:LBYS RS09100
gene id: 649349:LBYS_RS09100
uniprot id: E4RQT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

649349:LBYS RS03980
gene id: 649349:LBYS_RS03980
uniprot id: E4RQJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

649349:LBYS RS02970
gene id: 649349:LBYS_RS02970
uniprot id: E4RY36
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

649349:LBYS RS14845
gene id: 649349:LBYS_RS14845
uniprot id: E4RT95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS04570
gene id: 649349:LBYS_RS04570
uniprot id: E4RRK8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

649349:LBYS RS01860
gene id: 649349:LBYS_RS01860
uniprot id: E4RW10
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS13815
gene id: 649349:LBYS_RS13815
uniprot id: E4RQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

649349:LBYS RS09030
gene id: 649349:LBYS_RS09030
uniprot id: E4RQR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

649349:LBYS RS16070
gene id: 649349:LBYS_RS16070
uniprot id: E4RVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

649349:LBYS RS08030
gene id: 649349:LBYS_RS08030
uniprot id: E4RYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

649349:LBYS RS16510
gene id: 649349:LBYS_RS16510
uniprot id: E4RWL7
names: Similarity
messages: Belongs to the IlvD/Edd family.

649349:LBYS RS04190
gene id: 649349:LBYS_RS04190
uniprot id: E4RQZ9
names: Similarity
messages: Belongs to the SufE family.

649349:LBYS RS12840
gene id: 649349:LBYS_RS12840
uniprot id: E4RZ16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

649349:LBYS RS15375
gene id: 649349:LBYS_RS15375
uniprot id: E4RUK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS10885
gene id: 649349:LBYS_RS10885
uniprot id: E4RV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

649349:LBYS RS08185
gene id: 649349:LBYS_RS08185
uniprot id: E4RYV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

649349:LBYS RS10065
gene id: 649349:LBYS_RS10065
uniprot id: E4RT13
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

649349:LBYS RS07785
gene id: 649349:LBYS_RS07785
uniprot id: E4RY60
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

649349:LBYS RS07685
gene id: 649349:LBYS_RS07685
uniprot id: E4RXL9
names: Similarity
messages: Belongs to the glutamate synthase family.

649349:LBYS RS09290
gene id: 649349:LBYS_RS09290
uniprot id: E4RR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS12995
gene id: 649349:LBYS_RS12995
uniprot id: E4RZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

649349:LBYS RS13240
gene id: 649349:LBYS_RS13240
uniprot id: E4RQB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS04640
gene id: 649349:LBYS_RS04640
uniprot id: E4RRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

649349:LBYS RS08000
gene id: 649349:LBYS_RS08000
uniprot id: E4RYA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS03675
gene id: 649349:LBYS_RS03675
uniprot id: E4RQ19
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

649349:LBYS RS02430
gene id: 649349:LBYS_RS02430
uniprot id: E4RXB6
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS12835
gene id: 649349:LBYS_RS12835
uniprot id: E4RZ15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

649349:LBYS RS13890
gene id: 649349:LBYS_RS13890
uniprot id: E4RRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

649349:LBYS RS11255
gene id: 649349:LBYS_RS11255
uniprot id: E4RVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS17330
gene id: 649349:LBYS_RS17330
uniprot id: E4RYI7
names: Similarity
messages: Belongs to the peptidase U62 family.

649349:LBYS RS06120
gene id: 649349:LBYS_RS06120
uniprot id: E4RUB9
names: Similarity
messages: Belongs to the UPF0758 family.

649349:LBYS RS13430
gene id: 649349:LBYS_RS13430
uniprot id: E4RQE8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS08430
gene id: 649349:LBYS_RS08430
uniprot id: E4RZH7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

649349:LBYS RS12380
gene id: 649349:LBYS_RS12380
uniprot id: E4RYB5
names: Similarity
messages: Belongs to the peptidase S41A family.

649349:LBYS RS07340
gene id: 649349:LBYS_RS07340
uniprot id: E4RWY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

649349:LBYS RS09620
gene id: 649349:LBYS_RS09620
uniprot id: E4RRV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

649349:LBYS RS01335
gene id: 649349:LBYS_RS01335
uniprot id: E4RUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS09480
gene id: 649349:LBYS_RS09480
uniprot id: E4RRS3
names: Similarity
messages: Belongs to the threonine synthase family.

649349:LBYS RS12860
gene id: 649349:LBYS_RS12860
uniprot id: E4RZ20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

649349:LBYS RS04685
gene id: 649349:LBYS_RS04685
uniprot id: E4RRM9
names: Similarity
messages: Belongs to the pirin family.

649349:LBYS RS09390
gene id: 649349:LBYS_RS09390
uniprot id: E4RRA6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

649349:LBYS RS17015
gene id: 649349:LBYS_RS17015
uniprot id: E4RXW0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS06000
gene id: 649349:LBYS_RS06000
uniprot id: E4RU94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS16245
gene id: 649349:LBYS_RS16245
uniprot id: E4RWH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

649349:LBYS RS09015
gene id: 649349:LBYS_RS09015
uniprot id: E4RQR3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

649349:LBYS RS08640
gene id: 649349:LBYS_RS08640
uniprot id: E4RQ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10610
gene id: 649349:LBYS_RS10610
uniprot id: E4RUE0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS08695
gene id: 649349:LBYS_RS08695
uniprot id: E4RQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS06635
gene id: 649349:LBYS_RS06635
uniprot id: E4RVJ2
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS13685
gene id: 649349:LBYS_RS13685
uniprot id: E4RQW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS17695
gene id: 649349:LBYS_RS17695
uniprot id: E4RZ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

649349:LBYS RS05620
gene id: 649349:LBYS_RS05620
uniprot id: E4RTJ8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

649349:LBYS RS04250
gene id: 649349:LBYS_RS04250
uniprot id: E4RR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS14255
gene id: 649349:LBYS_RS14255
uniprot id: E4RRY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

649349:LBYS RS03115
gene id: 649349:LBYS_RS03115
uniprot id: E4RYN1
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

649349:LBYS RS01900
gene id: 649349:LBYS_RS01900
uniprot id: E4RW18
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

649349:LBYS RS02470
gene id: 649349:LBYS_RS02470
uniprot id: E4RXC4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS14330
gene id: 649349:LBYS_RS14330
uniprot id: E4RRZ6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

649349:LBYS RS07770
gene id: 649349:LBYS_RS07770
uniprot id: E4RY57
names: Similarity
messages: Belongs to the band 7/mec-2 family.

649349:LBYS RS13665
gene id: 649349:LBYS_RS13665
uniprot id: E4RQV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS11925
gene id: 649349:LBYS_RS11925
uniprot id: E4RX30
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

649349:LBYS RS04420
gene id: 649349:LBYS_RS04420
uniprot id: E4RR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

649349:LBYS RS08975
gene id: 649349:LBYS_RS08975
uniprot id: E4RQQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

649349:LBYS RS02705
gene id: 649349:LBYS_RS02705
uniprot id: E4RXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

649349:LBYS RS00030
gene id: 649349:LBYS_RS00030
uniprot id: E4RRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS15190
gene id: 649349:LBYS_RS15190
uniprot id: E4RTZ4
names: Similarity
messages: Belongs to the UPF0145 family.

649349:LBYS RS00040
gene id: 649349:LBYS_RS00040
uniprot id: E4RRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS15090
gene id: 649349:LBYS_RS15090
uniprot id: E4RTX4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

649349:LBYS RS09025
gene id: 649349:LBYS_RS09025
uniprot id: E4RQR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

649349:LBYS RS11505
gene id: 649349:LBYS_RS11505
uniprot id: E4RWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS13450
gene id: 649349:LBYS_RS13450
uniprot id: E4RQF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS13960
gene id: 649349:LBYS_RS13960
uniprot id: E4RRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS17110
gene id: 649349:LBYS_RS17110
uniprot id: E4RXX7
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS09045
gene id: 649349:LBYS_RS09045
uniprot id: E4RQR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS03715
gene id: 649349:LBYS_RS03715
uniprot id: E4RQ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

649349:LBYS RS14915
gene id: 649349:LBYS_RS14915
uniprot id: E4RTA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

649349:LBYS RS11885
gene id: 649349:LBYS_RS11885
uniprot id: E4RX22
names: Similarity
messages: Belongs to the TrpF family.

649349:LBYS RS16190
gene id: 649349:LBYS_RS16190
uniprot id: E4RVY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

649349:LBYS RS15785
gene id: 649349:LBYS_RS15785
uniprot id: E4RV79
names: Similarity
messages: Belongs to the peptidase S49 family.

649349:LBYS RS09090
gene id: 649349:LBYS_RS09090
uniprot id: E4RQS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

649349:LBYS RS09450
gene id: 649349:LBYS_RS09450
uniprot id: E4RRR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

649349:LBYS RS13025
gene id: 649349:LBYS_RS13025
uniprot id: E4RZN0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

649349:LBYS RS12555
gene id: 649349:LBYS_RS12555
uniprot id: E4RYE4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS00480
gene id: 649349:LBYS_RS00480
uniprot id: E4RSP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

649349:LBYS RS15805
gene id: 649349:LBYS_RS15805
uniprot id: E4RV83
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03180
gene id: 649349:LBYS_RS03180
uniprot id: E4RYP4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

649349:LBYS RS11410
gene id: 649349:LBYS_RS11410
uniprot id: E4RVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

649349:LBYS RS06030
gene id: 649349:LBYS_RS06030
uniprot id: E4RUA0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03170
gene id: 649349:LBYS_RS03170
uniprot id: E4RYP2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

649349:LBYS RS08690
gene id: 649349:LBYS_RS08690
uniprot id: E4RQ79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS11425
gene id: 649349:LBYS_RS11425
uniprot id: E4RVS3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

649349:LBYS RS03150
gene id: 649349:LBYS_RS03150
uniprot id: E4RYN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

649349:LBYS RS01750
gene id: 649349:LBYS_RS01750
uniprot id: E4RVE5
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS10715
gene id: 649349:LBYS_RS10715
uniprot id: E4RUG1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

649349:LBYS RS12575
gene id: 649349:LBYS_RS12575
uniprot id: E4RYE8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS10225
gene id: 649349:LBYS_RS10225
uniprot id: E4RT47
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

649349:LBYS RS15740
gene id: 649349:LBYS_RS15740
uniprot id: E4RV70
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00490
gene id: 649349:LBYS_RS00490
uniprot id: E4RSP2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

649349:LBYS RS09485
gene id: 649349:LBYS_RS09485
uniprot id: E4RRS4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

649349:LBYS RS16835
gene id: 649349:LBYS_RS16835
uniprot id: E4RXA5
names: Similarity
messages: Belongs to the NodU/CmcH family.

649349:LBYS RS00560
gene id: 649349:LBYS_RS00560
uniprot id: E4RSQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS06235
gene id: 649349:LBYS_RS06235
uniprot id: E4RUV3
names: Similarity
messages: Belongs to the pirin family.

649349:LBYS RS18070
gene id: 649349:LBYS_RS18070
uniprot id: E4RSR4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

649349:LBYS RS17795
gene id: 649349:LBYS_RS17795
uniprot id: E4RZ93
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS14710
gene id: 649349:LBYS_RS14710
uniprot id: E4RT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS10925
gene id: 649349:LBYS_RS10925
uniprot id: E4RV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS14860
gene id: 649349:LBYS_RS14860
uniprot id: E4RT98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

649349:LBYS RS09040
gene id: 649349:LBYS_RS09040
uniprot id: E4RQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

649349:LBYS RS05020
gene id: 649349:LBYS_RS05020
uniprot id: E4RS93
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS08495
gene id: 649349:LBYS_RS08495
uniprot id: E4RZJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

649349:LBYS RS04410
gene id: 649349:LBYS_RS04410
uniprot id: E4RR43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

649349:LBYS RS17135
gene id: 649349:LBYS_RS17135
uniprot id: E4RXY2
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

649349:LBYS RS11190
gene id: 649349:LBYS_RS11190
uniprot id: E4RVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS05825
gene id: 649349:LBYS_RS05825
uniprot id: E4RTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

649349:LBYS RS14215
gene id: 649349:LBYS_RS14215
uniprot id: E4RRX4
names: Similarity
messages: Belongs to the DEAD box helicase family.

649349:LBYS RS11365
gene id: 649349:LBYS_RS11365
uniprot id: E4RVR2
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS16660
gene id: 649349:LBYS_RS16660
uniprot id: E4RX68
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

649349:LBYS RS18025
gene id: 649349:LBYS_RS18025
uniprot id: E4RZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

649349:LBYS RS01065
gene id: 649349:LBYS_RS01065
uniprot id: E4RU30
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

649349:LBYS RS17180
gene id: 649349:LBYS_RS17180
uniprot id: E4RXZ1
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS12700
gene id: 649349:LBYS_RS12700
uniprot id: E4RYY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

649349:LBYS RS06255
gene id: 649349:LBYS_RS06255
uniprot id: E4RUV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

649349:LBYS RS17630
gene id: 649349:LBYS_RS17630
uniprot id: E4RZ60
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

649349:LBYS RS15520
gene id: 649349:LBYS_RS15520
uniprot id: E4RUM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS07180
gene id: 649349:LBYS_RS07180
uniprot id: E4RWV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS17720
gene id: 649349:LBYS_RS17720
uniprot id: E4RZ78
names: Similarity
messages: Belongs to the YciI family.

649349:LBYS RS03620
gene id: 649349:LBYS_RS03620
uniprot id: E4RQ09
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

649349:LBYS RS05555
gene id: 649349:LBYS_RS05555
uniprot id: E4RTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

649349:LBYS RS04110
gene id: 649349:LBYS_RS04110
uniprot id: E4RQL2
names: Similarity
messages: Belongs to the pirin family.

649349:LBYS RS03310
gene id: 649349:LBYS_RS03310
uniprot id: E4RYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

649349:LBYS RS07895
gene id: 649349:LBYS_RS07895
uniprot id: E4RY82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

649349:LBYS RS06505
gene id: 649349:LBYS_RS06505
uniprot id: E4RVG6
names: Similarity
messages: Belongs to the UPF0162 family.

649349:LBYS RS09005
gene id: 649349:LBYS_RS09005
uniprot id: E4RQR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS15685
gene id: 649349:LBYS_RS15685
uniprot id: E4RV59
names: Similarity
messages: Belongs to the RutC family.

649349:LBYS RS15295
gene id: 649349:LBYS_RS15295
uniprot id: E4RU14
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

649349:LBYS RS17120
gene id: 649349:LBYS_RS17120
uniprot id: E4RXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Secreted

649349:LBYS RS00010
gene id: 649349:LBYS_RS00010
uniprot id: E4RRG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

649349:LBYS RS10310
gene id: 649349:LBYS_RS10310
uniprot id: E4RTP8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

649349:LBYS RS07855
gene id: 649349:LBYS_RS07855
uniprot id: E4RY74
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS04425
gene id: 649349:LBYS_RS04425
uniprot id: E4RR46
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS02425
gene id: 649349:LBYS_RS02425
uniprot id: E4RXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS16265
gene id: 649349:LBYS_RS16265
uniprot id: E4RWH4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

649349:LBYS RS06475
gene id: 649349:LBYS_RS06475
uniprot id: E4RVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

649349:LBYS RS16300
gene id: 649349:LBYS_RS16300
uniprot id: E4RWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

649349:LBYS RS10935
gene id: 649349:LBYS_RS10935
uniprot id: E4RV10
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17160
gene id: 649349:LBYS_RS17160
uniprot id: E4RXY7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

649349:LBYS RS14080
gene id: 649349:LBYS_RS14080
uniprot id: E4RRE8
names: Similarity
messages: Belongs to the MreC family.

649349:LBYS RS13355
gene id: 649349:LBYS_RS13355
uniprot id: E4RQD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

649349:LBYS RS17220
gene id: 649349:LBYS_RS17220
uniprot id: E4RYG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS09055
gene id: 649349:LBYS_RS09055
uniprot id: E4RQS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

649349:LBYS RS01340
gene id: 649349:LBYS_RS01340
uniprot id: E4RUQ7
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS07405
gene id: 649349:LBYS_RS07405
uniprot id: E4RWZ4
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

649349:LBYS RS06460
gene id: 649349:LBYS_RS06460
uniprot id: E4RVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

649349:LBYS RS13070
gene id: 649349:LBYS_RS13070
uniprot id: E4RZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

649349:LBYS RS12240
gene id: 649349:LBYS_RS12240
uniprot id: E4RXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

649349:LBYS RS04670
gene id: 649349:LBYS_RS04670
uniprot id: E4RRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS04360
gene id: 649349:LBYS_RS04360
uniprot id: E4RR33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

649349:LBYS RS12195
gene id: 649349:LBYS_RS12195
uniprot id: E4RXQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS12930
gene id: 649349:LBYS_RS12930
uniprot id: E4RZL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

649349:LBYS RS12525
gene id: 649349:LBYS_RS12525
uniprot id: E4RYD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

649349:LBYS RS17095
gene id: 649349:LBYS_RS17095
uniprot id: E4RXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

649349:LBYS RS15850
gene id: 649349:LBYS_RS15850
uniprot id: E4RV92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS07865
gene id: 649349:LBYS_RS07865
uniprot id: E4RY76
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

649349:LBYS RS03015
gene id: 649349:LBYS_RS03015
uniprot id: E4RY45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

649349:LBYS RS13075
gene id: 649349:LBYS_RS13075
uniprot id: E4RZP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

649349:LBYS RS15215
gene id: 649349:LBYS_RS15215
uniprot id: E4RTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS02360
gene id: 649349:LBYS_RS02360
uniprot id: E4RWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

649349:LBYS RS16125
gene id: 649349:LBYS_RS16125
uniprot id: E4RVX6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

649349:LBYS RS14470
gene id: 649349:LBYS_RS14470
uniprot id: E4RSI7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS13590
gene id: 649349:LBYS_RS13590
uniprot id: E4RQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

649349:LBYS RS15405
gene id: 649349:LBYS_RS15405
uniprot id: E4RUK6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

649349:LBYS RS09000
gene id: 649349:LBYS_RS09000
uniprot id: E4RQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

649349:LBYS RS05815
gene id: 649349:LBYS_RS05815
uniprot id: E4RTN4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

649349:LBYS RS02940
gene id: 649349:LBYS_RS02940
uniprot id: E4RY30
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS08285
gene id: 649349:LBYS_RS08285
uniprot id: E4RYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

649349:LBYS RS14800
gene id: 649349:LBYS_RS14800
uniprot id: E4RT86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

649349:LBYS RS06580
gene id: 649349:LBYS_RS06580
uniprot id: E4RVI1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

649349:LBYS RS16950
gene id: 649349:LBYS_RS16950
uniprot id: E4RXU7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03140
gene id: 649349:LBYS_RS03140
uniprot id: E4RYN6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

649349:LBYS RS06400
gene id: 649349:LBYS_RS06400
uniprot id: E4RUY5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS07300
gene id: 649349:LBYS_RS07300
uniprot id: E4RWX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

649349:LBYS RS17905
gene id: 649349:LBYS_RS17905
uniprot id: E4RZU1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

649349:LBYS RS13020
gene id: 649349:LBYS_RS13020
uniprot id: E4RZM9
names: Similarity
messages: Belongs to the LOG family.

649349:LBYS RS10575
gene id: 649349:LBYS_RS10575
uniprot id: E4RUD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

649349:LBYS RS17555
gene id: 649349:LBYS_RS17555
uniprot id: E4RZ45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

649349:LBYS RS16115
gene id: 649349:LBYS_RS16115
uniprot id: E4RVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS14260
gene id: 649349:LBYS_RS14260
uniprot id: E4RRY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

649349:LBYS RS10165
gene id: 649349:LBYS_RS10165
uniprot id: E4RT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

649349:LBYS RS10835
gene id: 649349:LBYS_RS10835
uniprot id: E4RUI4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00350
gene id: 649349:LBYS_RS00350
uniprot id: E4RS48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

649349:LBYS RS06750
gene id: 649349:LBYS_RS06750
uniprot id: E4RVL1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

649349:LBYS RS10700
gene id: 649349:LBYS_RS10700
uniprot id: E4RUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

649349:LBYS RS04445
gene id: 649349:LBYS_RS04445
uniprot id: E4RR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS10665
gene id: 649349:LBYS_RS10665
uniprot id: E4RUF1
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS00535
gene id: 649349:LBYS_RS00535
uniprot id: E4RSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

649349:LBYS RS02730
gene id: 649349:LBYS_RS02730
uniprot id: E4RXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS10615
gene id: 649349:LBYS_RS10615
uniprot id: E4RUE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

649349:LBYS RS02725
gene id: 649349:LBYS_RS02725
uniprot id: E4RXH1
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11895
gene id: 649349:LBYS_RS11895
uniprot id: E4RX24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS06210
gene id: 649349:LBYS_RS06210
uniprot id: E4RUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS05955
gene id: 649349:LBYS_RS05955
uniprot id: E4RU85
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS05570
gene id: 649349:LBYS_RS05570
uniprot id: E4RTI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS17085
gene id: 649349:LBYS_RS17085
uniprot id: E4RXX2
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS13580
gene id: 649349:LBYS_RS13580
uniprot id: E4RQU2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

649349:LBYS RS11765
gene id: 649349:LBYS_RS11765
uniprot id: E4RWG6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11805
gene id: 649349:LBYS_RS11805
uniprot id: E4RX08
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS04295
gene id: 649349:LBYS_RS04295
uniprot id: E4RR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS06195
gene id: 649349:LBYS_RS06195
uniprot id: E4RUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

649349:LBYS RS11575
gene id: 649349:LBYS_RS11575
uniprot id: E4RWC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS01200
gene id: 649349:LBYS_RS01200
uniprot id: E4RU57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS14070
gene id: 649349:LBYS_RS14070
uniprot id: E4RRE6
names: Similarity
messages: Belongs to the IMPACT family.

649349:LBYS RS05600
gene id: 649349:LBYS_RS05600
uniprot id: E4RTJ4
names: Similarity
messages: Belongs to the thioredoxin family.

649349:LBYS RS09660
gene id: 649349:LBYS_RS09660
uniprot id: E4RRV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

649349:LBYS RS16140
gene id: 649349:LBYS_RS16140
uniprot id: E4RVX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS10565
gene id: 649349:LBYS_RS10565
uniprot id: E4RTU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS00035
gene id: 649349:LBYS_RS00035
uniprot id: E4RRH2
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS13800
gene id: 649349:LBYS_RS13800
uniprot id: E4RQY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

649349:LBYS RS11645
gene id: 649349:LBYS_RS11645
uniprot id: E4RWE2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

649349:LBYS RS11380
gene id: 649349:LBYS_RS11380
uniprot id: E4RVR5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

649349:LBYS RS16665
gene id: 649349:LBYS_RS16665
uniprot id: E4RX69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

649349:LBYS RS16090
gene id: 649349:LBYS_RS16090
uniprot id: E4RVW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

649349:LBYS RS14265
gene id: 649349:LBYS_RS14265
uniprot id: E4RRY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

649349:LBYS RS14590
gene id: 649349:LBYS_RS14590
uniprot id: E4RSL2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

649349:LBYS RS07860
gene id: 649349:LBYS_RS07860
uniprot id: E4RY75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

649349:LBYS RS17935
gene id: 649349:LBYS_RS17935
uniprot id: E4RZU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

649349:LBYS RS03160
gene id: 649349:LBYS_RS03160
uniprot id: E4RYP0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

649349:LBYS RS08415
gene id: 649349:LBYS_RS08415
uniprot id: E4RZH3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

649349:LBYS RS02350
gene id: 649349:LBYS_RS02350
uniprot id: E4RWS6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

649349:LBYS RS08655
gene id: 649349:LBYS_RS08655
uniprot id: E4RQ72
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS13940
gene id: 649349:LBYS_RS13940
uniprot id: E4RRC4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

649349:LBYS RS14545
gene id: 649349:LBYS_RS14545
uniprot id: E4RSK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

649349:LBYS RS09375
gene id: 649349:LBYS_RS09375
uniprot id: E4RRA3
names: Similarity
messages: Belongs to the DapA family.

649349:LBYS RS06970
gene id: 649349:LBYS_RS06970
uniprot id: E4RW81
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

649349:LBYS RS13865
gene id: 649349:LBYS_RS13865
uniprot id: E4RRA9
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS13850
gene id: 649349:LBYS_RS13850
uniprot id: E4RQZ6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

649349:LBYS RS14055
gene id: 649349:LBYS_RS14055
uniprot id: E4RRE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

649349:LBYS RS08250
gene id: 649349:LBYS_RS08250
uniprot id: E4RYW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

649349:LBYS RS15080
gene id: 649349:LBYS_RS15080
uniprot id: E4RTX2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

649349:LBYS RS00385
gene id: 649349:LBYS_RS00385
uniprot id: E4RS55
names: Subcellular Location Annotation
messages: Mitochondrion

649349:LBYS RS11695
gene id: 649349:LBYS_RS11695
uniprot id: E4RWF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS09740
gene id: 649349:LBYS_RS09740
uniprot id: E4RSC5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS02330
gene id: 649349:LBYS_RS02330
uniprot id: E4RWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

649349:LBYS RS09070
gene id: 649349:LBYS_RS09070
uniprot id: E4RQS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

649349:LBYS RS14565
gene id: 649349:LBYS_RS14565
uniprot id: E4RSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

649349:LBYS RS08865
gene id: 649349:LBYS_RS08865
uniprot id: E4RQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

649349:LBYS RS11790
gene id: 649349:LBYS_RS11790
uniprot id: E4RX05
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

649349:LBYS RS02980
gene id: 649349:LBYS_RS02980
uniprot id: E4RY38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS16055
gene id: 649349:LBYS_RS16055
uniprot id: E4RVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

649349:LBYS RS10265
gene id: 649349:LBYS_RS10265
uniprot id: E4RT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS00225
gene id: 649349:LBYS_RS00225
uniprot id: E4RS23
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS06190
gene id: 649349:LBYS_RS06190
uniprot id: E4RUU4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

649349:LBYS RS18015
gene id: 649349:LBYS_RS18015
uniprot id: E4RZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

649349:LBYS RS17565
gene id: 649349:LBYS_RS17565
uniprot id: E4RZ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

649349:LBYS RS16305
gene id: 649349:LBYS_RS16305
uniprot id: E4RWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

649349:LBYS RS02535
gene id: 649349:LBYS_RS02535
uniprot id: E4RXD7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

649349:LBYS RS14555
gene id: 649349:LBYS_RS14555
uniprot id: E4RSK5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

649349:LBYS RS07805
gene id: 649349:LBYS_RS07805
uniprot id: E4RY64
names: Similarity
messages: Belongs to the universal stress protein A family.

649349:LBYS RS08550
gene id: 649349:LBYS_RS08550
uniprot id: E4RZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

649349:LBYS RS15240
gene id: 649349:LBYS_RS15240
uniprot id: E4RU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

649349:LBYS RS00090
gene id: 649349:LBYS_RS00090
uniprot id: E4RRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS05380
gene id: 649349:LBYS_RS05380
uniprot id: E4RSX2
names: Similarity
messages: Belongs to the DapA family.

649349:LBYS RS17525
gene id: 649349:LBYS_RS17525
uniprot id: E4RZ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS04575
gene id: 649349:LBYS_RS04575
uniprot id: E4RRK9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS05015
gene id: 649349:LBYS_RS05015
uniprot id: E4RS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

649349:LBYS RS14250
gene id: 649349:LBYS_RS14250
uniprot id: E4RRY1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS04650
gene id: 649349:LBYS_RS04650
uniprot id: E4RRM4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11880
gene id: 649349:LBYS_RS11880
uniprot id: E4RX21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

649349:LBYS RS06795
gene id: 649349:LBYS_RS06795
uniprot id: E4RVM0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

649349:LBYS RS10690
gene id: 649349:LBYS_RS10690
uniprot id: E4RUF6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

649349:LBYS RS06465
gene id: 649349:LBYS_RS06465
uniprot id: E4RVF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

649349:LBYS RS19025
gene id: 649349:LBYS_RS19025
uniprot id: E4RSA6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

649349:LBYS RS00085
gene id: 649349:LBYS_RS00085
uniprot id: E4RRI2
names: Similarity
messages: Belongs to the TPP enzyme family.

649349:LBYS RS02975
gene id: 649349:LBYS_RS02975
uniprot id: E4RY37
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

649349:LBYS RS11350
gene id: 649349:LBYS_RS11350
uniprot id: E4RVQ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

649349:LBYS RS11815
gene id: 649349:LBYS_RS11815
uniprot id: E4RX10
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

649349:LBYS RS16060
gene id: 649349:LBYS_RS16060
uniprot id: E4RVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

649349:LBYS RS16940
gene id: 649349:LBYS_RS16940
uniprot id: E4RXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS11210
gene id: 649349:LBYS_RS11210
uniprot id: E4RVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

649349:LBYS RS08720
gene id: 649349:LBYS_RS08720
uniprot id: E4RQ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

649349:LBYS RS05915
gene id: 649349:LBYS_RS05915
uniprot id: E4RU77
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

649349:LBYS RS13555
gene id: 649349:LBYS_RS13555
uniprot id: E4RQH2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

649349:LBYS RS10905
gene id: 649349:LBYS_RS10905
uniprot id: E4RV04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

649349:LBYS RS10300
gene id: 649349:LBYS_RS10300
uniprot id: E4RTP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

649349:LBYS RS16565
gene id: 649349:LBYS_RS16565
uniprot id: E4RWM6
names: Similarity
messages: Belongs to the ArsC family.

649349:LBYS RS08740
gene id: 649349:LBYS_RS08740
uniprot id: E4RQ89
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

649349:LBYS RS18475
gene id: 649349:LBYS_RS18475
uniprot id: E4RVT7
names: Subcellular Location Annotation
messages: Cytoplasm

649349:LBYS RS15635
gene id: 649349:LBYS_RS15635
uniprot id: E4RV49
names: Similarity
messages: Belongs to the peptidase M16 family.

649349:LBYS RS07055
gene id: 649349:LBYS_RS07055
uniprot id: E4RW98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS08985
gene id: 649349:LBYS_RS08985
uniprot id: E4RQQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

649349:LBYS RS12745
gene id: 649349:LBYS_RS12745
uniprot id: E4RYZ8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

649349:LBYS RS11315
gene id: 649349:LBYS_RS11315
uniprot id: E4RVQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS06530
gene id: 649349:LBYS_RS06530
uniprot id: E4RVH1
names: Similarity
messages: Belongs to the peptidase M24B family.

649349:LBYS RS07360
gene id: 649349:LBYS_RS07360
uniprot id: E4RWY7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS13380
gene id: 649349:LBYS_RS13380
uniprot id: E4RQD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

649349:LBYS RS05530
gene id: 649349:LBYS_RS05530
uniprot id: E4RSZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

649349:LBYS RS16590
gene id: 649349:LBYS_RS16590
uniprot id: E4RX56
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

649349:LBYS RS14685
gene id: 649349:LBYS_RS14685
uniprot id: E4RT63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

649349:LBYS RS04925
gene id: 649349:LBYS_RS04925
uniprot id: E4RS74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

649349:LBYS RS08820
gene id: 649349:LBYS_RS08820
uniprot id: E4RQA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS01035
gene id: 649349:LBYS_RS01035
uniprot id: E4RU25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS11545
gene id: 649349:LBYS_RS11545
uniprot id: E4RWC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

649349:LBYS RS01145
gene id: 649349:LBYS_RS01145
uniprot id: E4RU46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

649349:LBYS RS13105
gene id: 649349:LBYS_RS13105
uniprot id: E4RZP6
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS00220
gene id: 649349:LBYS_RS00220
uniprot id: E4RS22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS13895
gene id: 649349:LBYS_RS13895
uniprot id: E4RRB5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09980
gene id: 649349:LBYS_RS09980
uniprot id: E4RSG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS12810
gene id: 649349:LBYS_RS12810
uniprot id: E4RZ10
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS16685
gene id: 649349:LBYS_RS16685
uniprot id: E4RX73
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS15260
gene id: 649349:LBYS_RS15260
uniprot id: E4RU07
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

649349:LBYS RS10340
gene id: 649349:LBYS_RS10340
uniprot id: E4RTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

649349:LBYS RS14675
gene id: 649349:LBYS_RS14675
uniprot id: E4RT61
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

649349:LBYS RS07460
gene id: 649349:LBYS_RS07460
uniprot id: E4RXH6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

649349:LBYS RS02905
gene id: 649349:LBYS_RS02905
uniprot id: E4RY23
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS06610
gene id: 649349:LBYS_RS06610
uniprot id: E4RVI7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

649349:LBYS RS16620
gene id: 649349:LBYS_RS16620
uniprot id: E4RX61
names: Similarity
messages: Belongs to the citrate synthase family.

649349:LBYS RS02510
gene id: 649349:LBYS_RS02510
uniprot id: E4RXD2
names: Subcellular Location Annotation
messages: Cell inner membrane

649349:LBYS RS01080
gene id: 649349:LBYS_RS01080
uniprot id: E4RU33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

649349:LBYS RS16120
gene id: 649349:LBYS_RS16120
uniprot id: E4RVX5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

649349:LBYS RS15170
gene id: 649349:LBYS_RS15170
uniprot id: E4RTZ0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

649349:LBYS RS09770
gene id: 649349:LBYS_RS09770
uniprot id: E4RSD0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

649349:LBYS RS03520
gene id: 649349:LBYS_RS03520
uniprot id: E4RZD4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

649349:LBYS RS17820
gene id: 649349:LBYS_RS17820
uniprot id: E4RZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS10365
gene id: 649349:LBYS_RS10365
uniprot id: E4RTR0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

649349:LBYS RS15400
gene id: 649349:LBYS_RS15400
uniprot id: E4RUK5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

649349:LBYS RS01120
gene id: 649349:LBYS_RS01120
uniprot id: E4RU41
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

649349:LBYS RS05000
gene id: 649349:LBYS_RS05000
uniprot id: E4RS89
names: Similarity
messages: Belongs to the ClpA/ClpB family.

649349:LBYS RS06265
gene id: 649349:LBYS_RS06265
uniprot id: E4RUV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS07480
gene id: 649349:LBYS_RS07480
uniprot id: E4RXI0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10210
gene id: 649349:LBYS_RS10210
uniprot id: E4RT44
names: Similarity
messages: Belongs to the aspartokinase family.

649349:LBYS RS10635
gene id: 649349:LBYS_RS10635
uniprot id: E4RUE5
names: Similarity
messages: Belongs to the GbsR family.

649349:LBYS RS05165
gene id: 649349:LBYS_RS05165
uniprot id: E4RST4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS07305
gene id: 649349:LBYS_RS07305
uniprot id: E4RWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

649349:LBYS RS02925
gene id: 649349:LBYS_RS02925
uniprot id: E4RY27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10080
gene id: 649349:LBYS_RS10080
uniprot id: E4RT16
names: Similarity
messages: Belongs to the pyruvate kinase family.

649349:LBYS RS11585
gene id: 649349:LBYS_RS11585
uniprot id: E4RWD0
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

649349:LBYS RS01800
gene id: 649349:LBYS_RS01800
uniprot id: E4RVF5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11475
gene id: 649349:LBYS_RS11475
uniprot id: E4RVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

649349:LBYS RS07520
gene id: 649349:LBYS_RS07520
uniprot id: E4RXI8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

649349:LBYS RS08685
gene id: 649349:LBYS_RS08685
uniprot id: E4RQ78
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

649349:LBYS RS05985
gene id: 649349:LBYS_RS05985
uniprot id: E4RU91
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

649349:LBYS RS05940
gene id: 649349:LBYS_RS05940
uniprot id: E4RU82
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

649349:LBYS RS18000
gene id: 649349:LBYS_RS18000
uniprot id: E4RZW2
names: Similarity
messages: Belongs to the peptidase S33 family.

649349:LBYS RS02370
gene id: 649349:LBYS_RS02370
uniprot id: E4RWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS11800
gene id: 649349:LBYS_RS11800
uniprot id: E4RX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

649349:LBYS RS11610
gene id: 649349:LBYS_RS11610
uniprot id: E4RWD5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03745
gene id: 649349:LBYS_RS03745
uniprot id: E4RQ34
names: Similarity
messages: Belongs to the peptidase S66 family.

649349:LBYS RS15310
gene id: 649349:LBYS_RS15310
uniprot id: E4RUI9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

649349:LBYS RS10745
gene id: 649349:LBYS_RS10745
uniprot id: E4RUG7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

649349:LBYS RS02480
gene id: 649349:LBYS_RS02480
uniprot id: E4RXC6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10495
gene id: 649349:LBYS_RS10495
uniprot id: E4RTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08055
gene id: 649349:LBYS_RS08055
uniprot id: E4RYS7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

649349:LBYS RS15185
gene id: 649349:LBYS_RS15185
uniprot id: E4RTZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

649349:LBYS RS15130
gene id: 649349:LBYS_RS15130
uniprot id: E4RTY1
names: Similarity
messages: Belongs to the peptidase S8 family.

649349:LBYS RS05935
gene id: 649349:LBYS_RS05935
uniprot id: E4RU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

649349:LBYS RS05840
gene id: 649349:LBYS_RS05840
uniprot id: E4RTN9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

649349:LBYS RS14100
gene id: 649349:LBYS_RS14100
uniprot id: E4RRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

649349:LBYS RS10375
gene id: 649349:LBYS_RS10375
uniprot id: E4RTR2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

649349:LBYS RS15100
gene id: 649349:LBYS_RS15100
uniprot id: E4RTX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS10600
gene id: 649349:LBYS_RS10600
uniprot id: E4RUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

649349:LBYS RS03695
gene id: 649349:LBYS_RS03695
uniprot id: E4RQ23
names: Similarity
messages: Belongs to the sigma-54 factor family.

649349:LBYS RS02245
gene id: 649349:LBYS_RS02245
uniprot id: E4RWR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

649349:LBYS RS15560
gene id: 649349:LBYS_RS15560
uniprot id: E4RUN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

649349:LBYS RS00070
gene id: 649349:LBYS_RS00070
uniprot id: E4RRH9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

649349:LBYS RS06245
gene id: 649349:LBYS_RS06245
uniprot id: E4RUV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

649349:LBYS RS09985
gene id: 649349:LBYS_RS09985
uniprot id: E4RSG9
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS01575
gene id: 649349:LBYS_RS01575
uniprot id: E4RVB5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

649349:LBYS RS15245
gene id: 649349:LBYS_RS15245
uniprot id: E4RU04
names: Similarity
messages: Belongs to the AIR synthase family.

649349:LBYS RS10735
gene id: 649349:LBYS_RS10735
uniprot id: E4RUG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

649349:LBYS RS08980
gene id: 649349:LBYS_RS08980
uniprot id: E4RQQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

649349:LBYS RS04565
gene id: 649349:LBYS_RS04565
uniprot id: E4RRK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

649349:LBYS RS11325
gene id: 649349:LBYS_RS11325
uniprot id: E4RVQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

649349:LBYS RS04760
gene id: 649349:LBYS_RS04760
uniprot id: E4RRP2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

649349:LBYS RS14290
gene id: 649349:LBYS_RS14290
uniprot id: E4RRY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

649349:LBYS RS13330
gene id: 649349:LBYS_RS13330
uniprot id: E4RQC8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

649349:LBYS RS17390
gene id: 649349:LBYS_RS17390
uniprot id: E4RYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

649349:LBYS RS17265
gene id: 649349:LBYS_RS17265
uniprot id: E4RYH4
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

649349:LBYS RS15820
gene id: 649349:LBYS_RS15820
uniprot id: E4RV86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS02095
gene id: 649349:LBYS_RS02095
uniprot id: E4RWN1
names: Similarity
messages: Belongs to the AHA1 family.

649349:LBYS RS01755
gene id: 649349:LBYS_RS01755
uniprot id: E4RVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS15790
gene id: 649349:LBYS_RS15790
uniprot id: E4RV80
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS12800
gene id: 649349:LBYS_RS12800
uniprot id: E4RZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

649349:LBYS RS03895
gene id: 649349:LBYS_RS03895
uniprot id: E4RQH8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS01925
gene id: 649349:LBYS_RS01925
uniprot id: E4RW23
names: Similarity
messages: Belongs to the DEAD box helicase family.

649349:LBYS RS11005
gene id: 649349:LBYS_RS11005
uniprot id: E4RV19
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

649349:LBYS RS01465
gene id: 649349:LBYS_RS01465
uniprot id: E4RUS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS13415
gene id: 649349:LBYS_RS13415
uniprot id: E4RQE5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

649349:LBYS RS14395
gene id: 649349:LBYS_RS14395
uniprot id: E4RS09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

649349:LBYS RS06520
gene id: 649349:LBYS_RS06520
uniprot id: E4RVG9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

649349:LBYS RS16270
gene id: 649349:LBYS_RS16270
uniprot id: E4RWH5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS06275
gene id: 649349:LBYS_RS06275
uniprot id: E4RUW1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

649349:LBYS RS16005
gene id: 649349:LBYS_RS16005
uniprot id: E4RVV2
names: Similarity
messages: Belongs to the peptidase S41A family.

649349:LBYS RS13860
gene id: 649349:LBYS_RS13860
uniprot id: E4RQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08760
gene id: 649349:LBYS_RS08760
uniprot id: E4RQ93
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

649349:LBYS RS12705
gene id: 649349:LBYS_RS12705
uniprot id: E4RYZ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

649349:LBYS RS04130
gene id: 649349:LBYS_RS04130
uniprot id: E4RQL6
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS17550
gene id: 649349:LBYS_RS17550
uniprot id: E4RZ44
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

649349:LBYS RS15270
gene id: 649349:LBYS_RS15270
uniprot id: E4RU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

649349:LBYS RS16785
gene id: 649349:LBYS_RS16785
uniprot id: E4RX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08070
gene id: 649349:LBYS_RS08070
uniprot id: E4RYT0
names: Similarity
messages: Belongs to the UxaA family.

649349:LBYS RS11490
gene id: 649349:LBYS_RS11490
uniprot id: E4RVT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

649349:LBYS RS09285
gene id: 649349:LBYS_RS09285
uniprot id: E4RR86
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS11450
gene id: 649349:LBYS_RS11450
uniprot id: E4RVS8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00985
gene id: 649349:LBYS_RS00985
uniprot id: E4RTI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS05765
gene id: 649349:LBYS_RS05765
uniprot id: E4RTM5
names: Similarity
messages: Belongs to the Dps family.

649349:LBYS RS07060
gene id: 649349:LBYS_RS07060
uniprot id: E4RW99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

649349:LBYS RS14570
gene id: 649349:LBYS_RS14570
uniprot id: E4RSK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

649349:LBYS RS14560
gene id: 649349:LBYS_RS14560
uniprot id: E4RSK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

649349:LBYS RS12440
gene id: 649349:LBYS_RS12440
uniprot id: E4RYC7
names: Similarity
messages: Belongs to the fabD family.

649349:LBYS RS08190
gene id: 649349:LBYS_RS08190
uniprot id: E4RYV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

649349:LBYS RS08230
gene id: 649349:LBYS_RS08230
uniprot id: E4RYW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

649349:LBYS RS14875
gene id: 649349:LBYS_RS14875
uniprot id: E4RTA1
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17970
gene id: 649349:LBYS_RS17970
uniprot id: E4RZV5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS09165
gene id: 649349:LBYS_RS09165
uniprot id: E4RR64
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10785
gene id: 649349:LBYS_RS10785
uniprot id: E4RUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

649349:LBYS RS11860
gene id: 649349:LBYS_RS11860
uniprot id: E4RX17
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS18350
gene id: 649349:LBYS_RS18350
uniprot id: E4RWG5
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10630
gene id: 649349:LBYS_RS10630
uniprot id: E4RUE4
names: Similarity
messages: Belongs to the DtxR/MntR family.

649349:LBYS RS06740
gene id: 649349:LBYS_RS06740
uniprot id: E4RVK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

649349:LBYS RS17805
gene id: 649349:LBYS_RS17805
uniprot id: E4RZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

649349:LBYS RS15890
gene id: 649349:LBYS_RS15890
uniprot id: E4RVA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS12230
gene id: 649349:LBYS_RS12230
uniprot id: E4RXQ7
names: Similarity
messages: Belongs to the serpin family.

649349:LBYS RS11870
gene id: 649349:LBYS_RS11870
uniprot id: E4RX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

649349:LBYS RS01685
gene id: 649349:LBYS_RS01685
uniprot id: E4RVD3
names: Subcellular Location Annotation
messages: Cytoplasm

649349:LBYS RS08355
gene id: 649349:LBYS_RS08355
uniprot id: E4RZG0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

649349:LBYS RS10190
gene id: 649349:LBYS_RS10190
uniprot id: E4RT39
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS00310
gene id: 649349:LBYS_RS00310
uniprot id: E4RS40
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

649349:LBYS RS15235
gene id: 649349:LBYS_RS15235
uniprot id: E4RU02
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

649349:LBYS RS17660
gene id: 649349:LBYS_RS17660
uniprot id: E4RZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

649349:LBYS RS03865
gene id: 649349:LBYS_RS03865
uniprot id: E4RQ55
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10920
gene id: 649349:LBYS_RS10920
uniprot id: E4RV07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

649349:LBYS RS13455
gene id: 649349:LBYS_RS13455
uniprot id: E4RQF2
names: Similarity
messages: Belongs to the peptidase S58 family.

649349:LBYS RS05730
gene id: 649349:LBYS_RS05730
uniprot id: E4RTM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

649349:LBYS RS15455
gene id: 649349:LBYS_RS15455
uniprot id: E4RUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

649349:LBYS RS11265
gene id: 649349:LBYS_RS11265
uniprot id: E4RVP1
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS07790
gene id: 649349:LBYS_RS07790
uniprot id: E4RY61
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

649349:LBYS RS17065
gene id: 649349:LBYS_RS17065
uniprot id: E4RXW8
names: Similarity
messages: Belongs to the GroES chaperonin family.

649349:LBYS RS04245
gene id: 649349:LBYS_RS04245
uniprot id: E4RR10
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS06965
gene id: 649349:LBYS_RS06965
uniprot id: E4RW80
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

649349:LBYS RS17150
gene id: 649349:LBYS_RS17150
uniprot id: E4RXY5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

649349:LBYS RS16345
gene id: 649349:LBYS_RS16345
uniprot id: E4RWJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS02945
gene id: 649349:LBYS_RS02945
uniprot id: E4RY31
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00045
gene id: 649349:LBYS_RS00045
uniprot id: E4RRH4
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS13315
gene id: 649349:LBYS_RS13315
uniprot id: E4RQC5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS06065
gene id: 649349:LBYS_RS06065
uniprot id: E4RUA7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS07590
gene id: 649349:LBYS_RS07590
uniprot id: E4RXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

649349:LBYS RS04645
gene id: 649349:LBYS_RS04645
uniprot id: E4RRM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

649349:LBYS RS04390
gene id: 649349:LBYS_RS04390
uniprot id: E4RR39
names: Similarity
messages: Belongs to the glutamine synthetase family.

649349:LBYS RS15485
gene id: 649349:LBYS_RS15485
uniprot id: E4RUM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

649349:LBYS RS17200
gene id: 649349:LBYS_RS17200
uniprot id: E4RYG1
names: Similarity
messages: Belongs to the YciI family.

649349:LBYS RS08960
gene id: 649349:LBYS_RS08960
uniprot id: E4RQQ2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

649349:LBYS RS17980
gene id: 649349:LBYS_RS17980
uniprot id: E4RZV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS14075
gene id: 649349:LBYS_RS14075
uniprot id: E4RRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

649349:LBYS RS05700
gene id: 649349:LBYS_RS05700
uniprot id: E4RTL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS12435
gene id: 649349:LBYS_RS12435
uniprot id: E4RYC6
names: Similarity
messages: Belongs to the RecJ family.

649349:LBYS RS11560
gene id: 649349:LBYS_RS11560
uniprot id: E4RWC5
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS12420
gene id: 649349:LBYS_RS12420
uniprot id: E4RYC3
names: Similarity
messages: Belongs to the Skp family.

649349:LBYS RS14355
gene id: 649349:LBYS_RS14355
uniprot id: E4RS01
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

649349:LBYS RS01565
gene id: 649349:LBYS_RS01565
uniprot id: E4RVB3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

649349:LBYS RS17665
gene id: 649349:LBYS_RS17665
uniprot id: E4RZ67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

649349:LBYS RS15870
gene id: 649349:LBYS_RS15870
uniprot id: E4RV96
names: Similarity
messages: Belongs to the Skp family.

649349:LBYS RS07870
gene id: 649349:LBYS_RS07870
uniprot id: E4RY77
names: Similarity
messages: Belongs to the transglycosylase Slt family.

649349:LBYS RS09435
gene id: 649349:LBYS_RS09435
uniprot id: E4RRR4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

649349:LBYS RS14040
gene id: 649349:LBYS_RS14040
uniprot id: E4RRE0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

649349:LBYS RS13820
gene id: 649349:LBYS_RS13820
uniprot id: E4RQZ0
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

649349:LBYS RS01545
gene id: 649349:LBYS_RS01545
uniprot id: E4RVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

649349:LBYS RS02380
gene id: 649349:LBYS_RS02380
uniprot id: E4RWT2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

649349:LBYS RS14460
gene id: 649349:LBYS_RS14460
uniprot id: E4RSI4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS04615
gene id: 649349:LBYS_RS04615
uniprot id: E4RRL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

649349:LBYS RS05850
gene id: 649349:LBYS_RS05850
uniprot id: E4RTP1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

649349:LBYS RS13290
gene id: 649349:LBYS_RS13290
uniprot id: E4RQC0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

649349:LBYS RS19325
gene id: 649349:LBYS_RS19325
uniprot id: E4RZK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

649349:LBYS RS01115
gene id: 649349:LBYS_RS01115
uniprot id: E4RU40
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS04290
gene id: 649349:LBYS_RS04290
uniprot id: E4RR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

649349:LBYS RS15885
gene id: 649349:LBYS_RS15885
uniprot id: E4RV99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

649349:LBYS RS01945
gene id: 649349:LBYS_RS01945
uniprot id: E4RW27
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS16860
gene id: 649349:LBYS_RS16860
uniprot id: E4RXB0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS02640
gene id: 649349:LBYS_RS02640
uniprot id: E4RXF7
names: Similarity
messages: Belongs to the peptidase S8 family.

649349:LBYS RS13150
gene id: 649349:LBYS_RS13150
uniprot id: E4RZQ6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS15300
gene id: 649349:LBYS_RS15300
uniprot id: E4RUI7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09875
gene id: 649349:LBYS_RS09875
uniprot id: E4RSE7
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS01090
gene id: 649349:LBYS_RS01090
uniprot id: E4RU35
names: Similarity
messages: Belongs to the CarB family.

649349:LBYS RS15545
gene id: 649349:LBYS_RS15545
uniprot id: E4RUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

649349:LBYS RS10250
gene id: 649349:LBYS_RS10250
uniprot id: E4RT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

649349:LBYS RS15550
gene id: 649349:LBYS_RS15550
uniprot id: E4RUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS09500
gene id: 649349:LBYS_RS09500
uniprot id: E4RRS7
names: Similarity
messages: Belongs to the barstar family.

649349:LBYS RS10760
gene id: 649349:LBYS_RS10760
uniprot id: E4RUG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

649349:LBYS RS14475
gene id: 649349:LBYS_RS14475
uniprot id: E4RSI8
names: Similarity
messages: Belongs to the NDK family.

649349:LBYS RS08310
gene id: 649349:LBYS_RS08310
uniprot id: E4RZF1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

649349:LBYS RS08380
gene id: 649349:LBYS_RS08380
uniprot id: E4RZG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS11580
gene id: 649349:LBYS_RS11580
uniprot id: E4RWC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS16960
gene id: 649349:LBYS_RS16960
uniprot id: E4RXU9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS16100
gene id: 649349:LBYS_RS16100
uniprot id: E4RVX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS14795
gene id: 649349:LBYS_RS14795
uniprot id: E4RT85
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

649349:LBYS RS02185
gene id: 649349:LBYS_RS02185
uniprot id: E4RWP8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09970
gene id: 649349:LBYS_RS09970
uniprot id: E4RSG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS05350
gene id: 649349:LBYS_RS05350
uniprot id: E4RSW7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS11685
gene id: 649349:LBYS_RS11685
uniprot id: E4RWF0
names: Similarity
messages: Belongs to the YjdM family.

649349:LBYS RS08920
gene id: 649349:LBYS_RS08920
uniprot id: E4RQP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

649349:LBYS RS08825
gene id: 649349:LBYS_RS08825
uniprot id: E4RQA6
names: Similarity
messages: Belongs to the DapA family.

649349:LBYS RS14270
gene id: 649349:LBYS_RS14270
uniprot id: E4RRY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS05680
gene id: 649349:LBYS_RS05680
uniprot id: E4RTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

649349:LBYS RS06495
gene id: 649349:LBYS_RS06495
uniprot id: E4RVG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

649349:LBYS RS14175
gene id: 649349:LBYS_RS14175
uniprot id: E4RRG7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

649349:LBYS RS03250
gene id: 649349:LBYS_RS03250
uniprot id: E4RYQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

649349:LBYS RS10940
gene id: 649349:LBYS_RS10940
uniprot id: E4RV11
names: Similarity
messages: Belongs to the SCO1/2 family.

649349:LBYS RS14595
gene id: 649349:LBYS_RS14595
uniprot id: E4RSL3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

649349:LBYS RS13295
gene id: 649349:LBYS_RS13295
uniprot id: E4RQC1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

649349:LBYS RS16710
gene id: 649349:LBYS_RS16710
uniprot id: E4RX78
names: Similarity
messages: Belongs to the phosphohexose mutase family.

649349:LBYS RS00275
gene id: 649349:LBYS_RS00275
uniprot id: E4RS33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS14645
gene id: 649349:LBYS_RS14645
uniprot id: E4RSM3
names: Similarity
messages: Belongs to the Fur family.

649349:LBYS RS07570
gene id: 649349:LBYS_RS07570
uniprot id: E4RXJ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS09455
gene id: 649349:LBYS_RS09455
uniprot id: E4RRR8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

649349:LBYS RS08280
gene id: 649349:LBYS_RS08280
uniprot id: E4RYX2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

649349:LBYS RS04520
gene id: 649349:LBYS_RS04520
uniprot id: E4RRJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

649349:LBYS RS03755
gene id: 649349:LBYS_RS03755
uniprot id: E4RQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS00265
gene id: 649349:LBYS_RS00265
uniprot id: E4RS31
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

649349:LBYS RS11000
gene id: 649349:LBYS_RS11000
uniprot id: E4RV18
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

649349:LBYS RS05095
gene id: 649349:LBYS_RS05095
uniprot id: E4RSA8
names: Similarity
messages: Belongs to the arginine deiminase family.

649349:LBYS RS03735
gene id: 649349:LBYS_RS03735
uniprot id: E4RQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

649349:LBYS RS15775
gene id: 649349:LBYS_RS15775
uniprot id: E4RV77
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

649349:LBYS RS14180
gene id: 649349:LBYS_RS14180
uniprot id: E4RRW9
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03805
gene id: 649349:LBYS_RS03805
uniprot id: E4RQ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

649349:LBYS RS03685
gene id: 649349:LBYS_RS03685
uniprot id: E4RQ21
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

649349:LBYS RS17125
gene id: 649349:LBYS_RS17125
uniprot id: E4RXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS07150
gene id: 649349:LBYS_RS07150
uniprot id: E4RWU4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

649349:LBYS RS11825
gene id: 649349:LBYS_RS11825
uniprot id: E4RX13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

649349:LBYS RS00495
gene id: 649349:LBYS_RS00495
uniprot id: E4RSP3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

649349:LBYS RS02445
gene id: 649349:LBYS_RS02445
uniprot id: E4RXB9
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10020
gene id: 649349:LBYS_RS10020
uniprot id: E4RT04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

649349:LBYS RS08770
gene id: 649349:LBYS_RS08770
uniprot id: E4RQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08895
gene id: 649349:LBYS_RS08895
uniprot id: E4RQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS12695
gene id: 649349:LBYS_RS12695
uniprot id: E4RYY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

649349:LBYS RS00315
gene id: 649349:LBYS_RS00315
uniprot id: E4RS41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS03435
gene id: 649349:LBYS_RS03435
uniprot id: E4RZB9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

649349:LBYS RS10545
gene id: 649349:LBYS_RS10545
uniprot id: E4RTU4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS14530
gene id: 649349:LBYS_RS14530
uniprot id: E4RSK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

649349:LBYS RS13765
gene id: 649349:LBYS_RS13765
uniprot id: E4RQX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

649349:LBYS RS00200
gene id: 649349:LBYS_RS00200
uniprot id: E4RS18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS11305
gene id: 649349:LBYS_RS11305
uniprot id: E4RVP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS03600
gene id: 649349:LBYS_RS03600
uniprot id: E4RQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS12790
gene id: 649349:LBYS_RS12790
uniprot id: E4RZ06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

649349:LBYS RS15915
gene id: 649349:LBYS_RS15915
uniprot id: E4RVA5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

649349:LBYS RS10050
gene id: 649349:LBYS_RS10050
uniprot id: E4RT10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

649349:LBYS RS06550
gene id: 649349:LBYS_RS06550
uniprot id: E4RVH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS17985
gene id: 649349:LBYS_RS17985
uniprot id: E4RZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

649349:LBYS RS05470
gene id: 649349:LBYS_RS05470
uniprot id: E4RSY6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS10915
gene id: 649349:LBYS_RS10915
uniprot id: E4RV06
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS00305
gene id: 649349:LBYS_RS00305
uniprot id: E4RS39
names: Similarity
messages: Belongs to the ribF family.

649349:LBYS RS14725
gene id: 649349:LBYS_RS14725
uniprot id: E4RT71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS06285
gene id: 649349:LBYS_RS06285
uniprot id: E4RUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS08715
gene id: 649349:LBYS_RS08715
uniprot id: E4RQ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

649349:LBYS RS02775
gene id: 649349:LBYS_RS02775
uniprot id: E4RXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

649349:LBYS RS14375
gene id: 649349:LBYS_RS14375
uniprot id: E4RS05
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS08670
gene id: 649349:LBYS_RS08670
uniprot id: E4RQ75
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

649349:LBYS RS16145
gene id: 649349:LBYS_RS16145
uniprot id: E4RVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

649349:LBYS RS17840
gene id: 649349:LBYS_RS17840
uniprot id: E4RZS8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

649349:LBYS RS14720
gene id: 649349:LBYS_RS14720
uniprot id: E4RT70
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

649349:LBYS RS12940
gene id: 649349:LBYS_RS12940
uniprot id: E4RZL2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

649349:LBYS RS05360
gene id: 649349:LBYS_RS05360
uniprot id: E4RSW9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

649349:LBYS RS18005
gene id: 649349:LBYS_RS18005
uniprot id: E4RZW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS13500
gene id: 649349:LBYS_RS13500
uniprot id: E4RQG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

649349:LBYS RS04265
gene id: 649349:LBYS_RS04265
uniprot id: E4RR14
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

649349:LBYS RS04935
gene id: 649349:LBYS_RS04935
uniprot id: E4RS76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS17335
gene id: 649349:LBYS_RS17335
uniprot id: E4RYI8
names: Similarity
messages: Belongs to the peptidase U62 family.

649349:LBYS RS16160
gene id: 649349:LBYS_RS16160
uniprot id: E4RVY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

649349:LBYS RS12320
gene id: 649349:LBYS_RS12320
uniprot id: E4RXS6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17175
gene id: 649349:LBYS_RS17175
uniprot id: E4RXZ0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

649349:LBYS RS16180
gene id: 649349:LBYS_RS16180
uniprot id: E4RVY7
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS01745
gene id: 649349:LBYS_RS01745
uniprot id: E4RVE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

649349:LBYS RS08510
gene id: 649349:LBYS_RS08510
uniprot id: E4RZJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS02590
gene id: 649349:LBYS_RS02590
uniprot id: E4RXE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

649349:LBYS RS14705
gene id: 649349:LBYS_RS14705
uniprot id: E4RT67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

649349:LBYS RS12405
gene id: 649349:LBYS_RS12405
uniprot id: E4RYC0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS14640
gene id: 649349:LBYS_RS14640
uniprot id: E4RSM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

649349:LBYS RS03080
gene id: 649349:LBYS_RS03080
uniprot id: E4RYM4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

649349:LBYS RS04415
gene id: 649349:LBYS_RS04415
uniprot id: E4RR44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

649349:LBYS RS17165
gene id: 649349:LBYS_RS17165
uniprot id: E4RXY8
names: Similarity
messages: Belongs to the peptidase S41A family.

649349:LBYS RS16810
gene id: 649349:LBYS_RS16810
uniprot id: E4RX99
names: Similarity
messages: Belongs to the GARS family.

649349:LBYS RS16970
gene id: 649349:LBYS_RS16970
uniprot id: E4RXV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS17880
gene id: 649349:LBYS_RS17880
uniprot id: E4RZT6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

649349:LBYS RS02090
gene id: 649349:LBYS_RS02090
uniprot id: E4RWN0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS12730
gene id: 649349:LBYS_RS12730
uniprot id: E4RYZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

649349:LBYS RS00550
gene id: 649349:LBYS_RS00550
uniprot id: E4RSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS14415
gene id: 649349:LBYS_RS14415
uniprot id: E4RSH5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

649349:LBYS RS09345
gene id: 649349:LBYS_RS09345
uniprot id: E4RR97
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

649349:LBYS RS07095
gene id: 649349:LBYS_RS07095
uniprot id: E4RWA6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS17885
gene id: 649349:LBYS_RS17885
uniprot id: E4RZT7
names: Similarity
messages: Belongs to the CinA family.

649349:LBYS RS06990
gene id: 649349:LBYS_RS06990
uniprot id: E4RW85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS05655
gene id: 649349:LBYS_RS05655
uniprot id: E4RTK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS00130
gene id: 649349:LBYS_RS00130
uniprot id: E4RRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

649349:LBYS RS12165
gene id: 649349:LBYS_RS12165
uniprot id: E4RXP6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

649349:LBYS RS07765
gene id: 649349:LBYS_RS07765
uniprot id: E4RY56
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS11555
gene id: 649349:LBYS_RS11555
uniprot id: E4RWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS18030
gene id: 649349:LBYS_RS18030
uniprot id: E4RZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

649349:LBYS RS17425
gene id: 649349:LBYS_RS17425
uniprot id: E4RYK7
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

649349:LBYS RS09760
gene id: 649349:LBYS_RS09760
uniprot id: E4RSC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS15115
gene id: 649349:LBYS_RS15115
uniprot id: E4RTX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

649349:LBYS RS09775
gene id: 649349:LBYS_RS09775
uniprot id: E4RSD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

649349:LBYS RS17580
gene id: 649349:LBYS_RS17580
uniprot id: E4RZ50
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

649349:LBYS RS08500
gene id: 649349:LBYS_RS08500
uniprot id: E4RZJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

649349:LBYS RS14620
gene id: 649349:LBYS_RS14620
uniprot id: E4RSL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

649349:LBYS RS08630
gene id: 649349:LBYS_RS08630
uniprot id: E4RQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

649349:LBYS RS07760
gene id: 649349:LBYS_RS07760
uniprot id: E4RY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08635
gene id: 649349:LBYS_RS08635
uniprot id: E4RQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

649349:LBYS RS07230
gene id: 649349:LBYS_RS07230
uniprot id: E4RWW1
names: Similarity
messages: Belongs to the DinB family.

649349:LBYS RS12595
gene id: 649349:LBYS_RS12595
uniprot id: E4RYF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS16945
gene id: 649349:LBYS_RS16945
uniprot id: E4RXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

649349:LBYS RS08900
gene id: 649349:LBYS_RS08900
uniprot id: E4RQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS13570
gene id: 649349:LBYS_RS13570
uniprot id: E4RQU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

649349:LBYS RS15330
gene id: 649349:LBYS_RS15330
uniprot id: E4RUJ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

649349:LBYS RS07220
gene id: 649349:LBYS_RS07220
uniprot id: E4RWV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

649349:LBYS RS05670
gene id: 649349:LBYS_RS05670
uniprot id: E4RTK8
names: Similarity
messages: Belongs to the glutamine synthetase family.

649349:LBYS RS09615
gene id: 649349:LBYS_RS09615
uniprot id: E4RRV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

649349:LBYS RS14690
gene id: 649349:LBYS_RS14690
uniprot id: E4RT64
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

649349:LBYS RS08370
gene id: 649349:LBYS_RS08370
uniprot id: E4RZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

649349:LBYS RS17870
gene id: 649349:LBYS_RS17870
uniprot id: E4RZT4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

649349:LBYS RS06240
gene id: 649349:LBYS_RS06240
uniprot id: E4RUV4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

649349:LBYS RS14240
gene id: 649349:LBYS_RS14240
uniprot id: E4RRX9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

649349:LBYS RS01555
gene id: 649349:LBYS_RS01555
uniprot id: E4RVB1
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09075
gene id: 649349:LBYS_RS09075
uniprot id: E4RQS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

649349:LBYS RS12510
gene id: 649349:LBYS_RS12510
uniprot id: E4RYD6
names: Similarity
messages: Belongs to the ribulokinase family.

649349:LBYS RS15165
gene id: 649349:LBYS_RS15165
uniprot id: E4RTY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS12300
gene id: 649349:LBYS_RS12300
uniprot id: E4RXS2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

649349:LBYS RS01305
gene id: 649349:LBYS_RS01305
uniprot id: E4RUQ1
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

649349:LBYS RS05835
gene id: 649349:LBYS_RS05835
uniprot id: E4RTN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

649349:LBYS RS05605
gene id: 649349:LBYS_RS05605
uniprot id: E4RTJ5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS15905
gene id: 649349:LBYS_RS15905
uniprot id: E4RVA3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

649349:LBYS RS03110
gene id: 649349:LBYS_RS03110
uniprot id: E4RYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

649349:LBYS RS00365
gene id: 649349:LBYS_RS00365
uniprot id: E4RS51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

649349:LBYS RS15040
gene id: 649349:LBYS_RS15040
uniprot id: E4RTW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

649349:LBYS RS13550
gene id: 649349:LBYS_RS13550
uniprot id: E4RQH1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

649349:LBYS RS11320
gene id: 649349:LBYS_RS11320
uniprot id: E4RVQ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

649349:LBYS RS12215
gene id: 649349:LBYS_RS12215
uniprot id: E4RXQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

649349:LBYS RS06380
gene id: 649349:LBYS_RS06380
uniprot id: E4RUY2
names: Similarity
messages: Belongs to the MQO family.

649349:LBYS RS14885
gene id: 649349:LBYS_RS14885
uniprot id: E4RTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS11200
gene id: 649349:LBYS_RS11200
uniprot id: E4RVM8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS03420
gene id: 649349:LBYS_RS03420
uniprot id: E4RZB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

649349:LBYS RS13405
gene id: 649349:LBYS_RS13405
uniprot id: E4RQE3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS11270
gene id: 649349:LBYS_RS11270
uniprot id: E4RVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS08665
gene id: 649349:LBYS_RS08665
uniprot id: E4RQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

649349:LBYS RS07445
gene id: 649349:LBYS_RS07445
uniprot id: E4RX02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

649349:LBYS RS09080
gene id: 649349:LBYS_RS09080
uniprot id: E4RQS6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

649349:LBYS RS15930
gene id: 649349:LBYS_RS15930
uniprot id: E4RVT6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

649349:LBYS RS13830
gene id: 649349:LBYS_RS13830
uniprot id: E4RQZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS06150
gene id: 649349:LBYS_RS06150
uniprot id: E4RUC5
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS15690
gene id: 649349:LBYS_RS15690
uniprot id: E4RV60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

649349:LBYS RS09035
gene id: 649349:LBYS_RS09035
uniprot id: E4RQR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

649349:LBYS RS11355
gene id: 649349:LBYS_RS11355
uniprot id: E4RVQ9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

649349:LBYS RS17340
gene id: 649349:LBYS_RS17340
uniprot id: E4RYI9
names: Similarity
messages: Belongs to the peptidase U62 family.

649349:LBYS RS13530
gene id: 649349:LBYS_RS13530
uniprot id: E4RQG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS13795
gene id: 649349:LBYS_RS13795
uniprot id: E4RQY5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

649349:LBYS RS05575
gene id: 649349:LBYS_RS05575
uniprot id: E4RTI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

649349:LBYS RS12900
gene id: 649349:LBYS_RS12900
uniprot id: E4RZ28
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

649349:LBYS RS05330
gene id: 649349:LBYS_RS05330
uniprot id: E4RSW3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS03585
gene id: 649349:LBYS_RS03585
uniprot id: E4RZE7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

649349:LBYS RS06515
gene id: 649349:LBYS_RS06515
uniprot id: E4RVG8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

649349:LBYS RS15025
gene id: 649349:LBYS_RS15025
uniprot id: E4RTW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

649349:LBYS RS11420
gene id: 649349:LBYS_RS11420
uniprot id: E4RVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

649349:LBYS RS07890
gene id: 649349:LBYS_RS07890
uniprot id: E4RY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

649349:LBYS RS09690
gene id: 649349:LBYS_RS09690
uniprot id: E4RRW5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS08995
gene id: 649349:LBYS_RS08995
uniprot id: E4RQQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

649349:LBYS RS08970
gene id: 649349:LBYS_RS08970
uniprot id: E4RQQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

649349:LBYS RS08965
gene id: 649349:LBYS_RS08965
uniprot id: E4RQQ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

649349:LBYS RS14580
gene id: 649349:LBYS_RS14580
uniprot id: E4RSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

649349:LBYS RS01850
gene id: 649349:LBYS_RS01850
uniprot id: E4RW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS06185
gene id: 649349:LBYS_RS06185
uniprot id: E4RUU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

649349:LBYS RS07145
gene id: 649349:LBYS_RS07145
uniprot id: E4RWU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

649349:LBYS RS10215
gene id: 649349:LBYS_RS10215
uniprot id: E4RT45
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

649349:LBYS RS12740
gene id: 649349:LBYS_RS12740
uniprot id: E4RYZ7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

649349:LBYS RS02355
gene id: 649349:LBYS_RS02355
uniprot id: E4RWS7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

649349:LBYS RS10295
gene id: 649349:LBYS_RS10295
uniprot id: E4RTP5
names: Similarity
messages: Belongs to the ParB family.

649349:LBYS RS16750
gene id: 649349:LBYS_RS16750
uniprot id: E4RX86
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

649349:LBYS RS14870
gene id: 649349:LBYS_RS14870
uniprot id: E4RTA0
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS09010
gene id: 649349:LBYS_RS09010
uniprot id: E4RQR2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS06360
gene id: 649349:LBYS_RS06360
uniprot id: E4RUX8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

649349:LBYS RS14245
gene id: 649349:LBYS_RS14245
uniprot id: E4RRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

649349:LBYS RS02170
gene id: 649349:LBYS_RS02170
uniprot id: E4RWP5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

649349:LBYS RS02300
gene id: 649349:LBYS_RS02300
uniprot id: E4RWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

649349:LBYS RS05845
gene id: 649349:LBYS_RS05845
uniprot id: E4RTP0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

649349:LBYS RS10135
gene id: 649349:LBYS_RS10135
uniprot id: E4RT28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

649349:LBYS RS11280
gene id: 649349:LBYS_RS11280
uniprot id: E4RVP4
names: Similarity
messages: Belongs to the DEAD box helicase family.

649349:LBYS RS12670
gene id: 649349:LBYS_RS12670
uniprot id: E4RYY3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

649349:LBYS RS04365
gene id: 649349:LBYS_RS04365
uniprot id: E4RR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

649349:LBYS RS10185
gene id: 649349:LBYS_RS10185
uniprot id: E4RT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS13525
gene id: 649349:LBYS_RS13525
uniprot id: E4RQG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

649349:LBYS RS11275
gene id: 649349:LBYS_RS11275
uniprot id: E4RVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

649349:LBYS RS14195
gene id: 649349:LBYS_RS14195
uniprot id: E4RRX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS07835
gene id: 649349:LBYS_RS07835
uniprot id: E4RY70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

649349:LBYS RS08700
gene id: 649349:LBYS_RS08700
uniprot id: E4RQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

649349:LBYS RS12685
gene id: 649349:LBYS_RS12685
uniprot id: E4RYY6
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS13335
gene id: 649349:LBYS_RS13335
uniprot id: E4RQC9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

649349:LBYS RS14625
gene id: 649349:LBYS_RS14625
uniprot id: E4RSL9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS11775
gene id: 649349:LBYS_RS11775
uniprot id: E4RWG8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

649349:LBYS RS05500
gene id: 649349:LBYS_RS05500
uniprot id: E4RSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS04580
gene id: 649349:LBYS_RS04580
uniprot id: E4RRL0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

649349:LBYS RS09060
gene id: 649349:LBYS_RS09060
uniprot id: E4RQS2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

649349:LBYS RS13805
gene id: 649349:LBYS_RS13805
uniprot id: E4RQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS17080
gene id: 649349:LBYS_RS17080
uniprot id: E4RXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS10490
gene id: 649349:LBYS_RS10490
uniprot id: E4RTT5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

649349:LBYS RS04180
gene id: 649349:LBYS_RS04180
uniprot id: E4RQM6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

649349:LBYS RS16855
gene id: 649349:LBYS_RS16855
uniprot id: E4RXA9
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS03410
gene id: 649349:LBYS_RS03410
uniprot id: E4RZB3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

649349:LBYS RS13515
gene id: 649349:LBYS_RS13515
uniprot id: E4RQG4
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS07885
gene id: 649349:LBYS_RS07885
uniprot id: E4RY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

649349:LBYS RS18065
gene id: 649349:LBYS_RS18065
uniprot id: E4RSQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

649349:LBYS RS10245
gene id: 649349:LBYS_RS10245
uniprot id: E4RT51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

649349:LBYS RS09170
gene id: 649349:LBYS_RS09170
uniprot id: E4RR65
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS10105
gene id: 649349:LBYS_RS10105
uniprot id: E4RT22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

649349:LBYS RS00295
gene id: 649349:LBYS_RS00295
uniprot id: E4RS37
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

649349:LBYS RS17480
gene id: 649349:LBYS_RS17480
uniprot id: E4RYL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

649349:LBYS RS11010
gene id: 649349:LBYS_RS11010
uniprot id: E4RV20
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

649349:LBYS RS13460
gene id: 649349:LBYS_RS13460
uniprot id: E4RQF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

649349:LBYS RS03615
gene id: 649349:LBYS_RS03615
uniprot id: E4RQ08
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

649349:LBYS RS00185
gene id: 649349:LBYS_RS00185
uniprot id: E4RS15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS00545
gene id: 649349:LBYS_RS00545
uniprot id: E4RSQ3
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS03285
gene id: 649349:LBYS_RS03285
uniprot id: E4RYR5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

649349:LBYS RS10285
gene id: 649349:LBYS_RS10285
uniprot id: E4RT59
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

649349:LBYS RS09400
gene id: 649349:LBYS_RS09400
uniprot id: E4RRA8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS07645
gene id: 649349:LBYS_RS07645
uniprot id: E4RXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

649349:LBYS RS00390
gene id: 649349:LBYS_RS00390
uniprot id: E4RS56
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

649349:LBYS RS04940
gene id: 649349:LBYS_RS04940
uniprot id: E4RS77
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

649349:LBYS RS09380
gene id: 649349:LBYS_RS09380
uniprot id: E4RRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

649349:LBYS RS12330
gene id: 649349:LBYS_RS12330
uniprot id: E4RXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

649349:LBYS RS09405
gene id: 649349:LBYS_RS09405
uniprot id: E4RRQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

649349:LBYS RS15910
gene id: 649349:LBYS_RS15910
uniprot id: E4RVA4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

649349:LBYS RS16095
gene id: 649349:LBYS_RS16095
uniprot id: E4RVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

649349:LBYS RS12675
gene id: 649349:LBYS_RS12675
uniprot id: E4RYY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

649349:LBYS RS05725
gene id: 649349:LBYS_RS05725
uniprot id: E4RTL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

649349:LBYS RS03070
gene id: 649349:LBYS_RS03070
uniprot id: E4RYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

649349:LBYS RS07840
gene id: 649349:LBYS_RS07840
uniprot id: E4RY71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

649349:LBYS RS09190
gene id: 649349:LBYS_RS09190
uniprot id: E4RR69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

649349:LBYS RS01485
gene id: 649349:LBYS_RS01485
uniprot id: E4RUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS11620
gene id: 649349:LBYS_RS11620
uniprot id: E4RWD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

649349:LBYS RS17635
gene id: 649349:LBYS_RS17635
uniprot id: E4RZ61
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

649349:LBYS RS15060
gene id: 649349:LBYS_RS15060
uniprot id: E4RTW8
names: Subcellular Location Annotation
messages: Membrane

649349:LBYS RS15615
gene id: 649349:LBYS_RS15615
uniprot id: E4RV45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

649349:LBYS RS12150
gene id: 649349:LBYS_RS12150
uniprot id: E4RXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS07545
gene id: 649349:LBYS_RS07545
uniprot id: E4RXJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

649349:LBYS RS08360
gene id: 649349:LBYS_RS08360
uniprot id: E4RZG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS09350
gene id: 649349:LBYS_RS09350
uniprot id: E4RR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

649349:LBYS RS15980
gene id: 649349:LBYS_RS15980
uniprot id: E4RVU6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

649349:LBYS RS10930
gene id: 649349:LBYS_RS10930
uniprot id: E4RV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS09320
gene id: 649349:LBYS_RS09320
uniprot id: E4RR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

649349:LBYS RS13990
gene id: 649349:LBYS_RS13990
uniprot id: E4RRD4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

649349:LBYS RS03225
gene id: 649349:LBYS_RS03225
uniprot id: E4RYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

649349:LBYS RS05390
gene id: 649349:LBYS_RS05390
uniprot id: E4RSX4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

649349:LBYS RS14200
gene id: 649349:LBYS_RS14200
uniprot id: E4RRX3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

649349:LBYS RS15920
gene id: 649349:LBYS_RS15920
uniprot id: E4RVA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

649349:LBYS RS05030
gene id: 649349:LBYS_RS05030
uniprot id: E4RS95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

649349:LBYS RS13660
gene id: 649349:LBYS_RS13660
uniprot id: E4RQV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

649349:LBYS RS13585
gene id: 649349:LBYS_RS13585
uniprot id: E4RQU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

649349:LBYS RS12610
gene id: 649349:LBYS_RS12610
uniprot id: E4RYF5
names: Similarity
messages: Belongs to the SusD family.

649349:LBYS RS02875
gene id: 649349:LBYS_RS02875
uniprot id: E4RY17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

649349:LBYS RS06490
gene id: 649349:LBYS_RS06490
uniprot id: E4RVG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

649349:LBYS RS16905
gene id: 649349:LBYS_RS16905
uniprot id: E4RXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

649349:LBYS RS11240
gene id: 649349:LBYS_RS11240
uniprot id: E4RVN6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

649349:LBYS RS14495
gene id: 649349:LBYS_RS14495
uniprot id: E4RSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

649349:LBYS RS12890
gene id: 649349:LBYS_RS12890
uniprot id: E4RZ26
names: Similarity
messages: Belongs to the UPF0047 family.

649349:LBYS RS12505
gene id: 649349:LBYS_RS12505
uniprot id: E4RYD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

649349:LBYS RS05480
gene id: 649349:LBYS_RS05480
uniprot id: E4RSY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

649349:LBYS RS15365
gene id: 649349:LBYS_RS15365
uniprot id: E4RUJ9
names: Similarity
messages: Belongs to the LOG family.

649349:LBYS RS14455
gene id: 649349:LBYS_RS14455
uniprot id: E4RSI3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.