645517:A6F65 RS00400
gene id: 645517:A6F65_RS00400
uniprot id: A0A1C7D4N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

645517:A6F65 RS01175
gene id: 645517:A6F65_RS01175
uniprot id: A0A1C7D523
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

645517:A6F65 RS06995
gene id: 645517:A6F65_RS06995
uniprot id: A0A1C7D8T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

645517:A6F65 RS01570
gene id: 645517:A6F65_RS01570
uniprot id: A0A1C7D5A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

645517:A6F65 RS06875
gene id: 645517:A6F65_RS06875
uniprot id: A0A1C7D8C2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

645517:A6F65 RS06985
gene id: 645517:A6F65_RS06985
uniprot id: A0A1C7D8C7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS11260
gene id: 645517:A6F65_RS11260
uniprot id: A0A1C7DAV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

645517:A6F65 RS12205
gene id: 645517:A6F65_RS12205
uniprot id: A0A1C7DBR9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

645517:A6F65 RS07610
gene id: 645517:A6F65_RS07610
uniprot id: A0A1C7D8R9
names: Similarity
messages: Belongs to the transketolase family.

645517:A6F65 RS03470
gene id: 645517:A6F65_RS03470
uniprot id: A0A1C7D6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

645517:A6F65 RS07115
gene id: 645517:A6F65_RS07115
uniprot id: A0A1C7D8I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS06385
gene id: 645517:A6F65_RS06385
uniprot id: A0A1C7D825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

645517:A6F65 RS03765
gene id: 645517:A6F65_RS03765
uniprot id: A0A1C7D6K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

645517:A6F65 RS12275
gene id: 645517:A6F65_RS12275
uniprot id: A0A1C7DBX7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00465
gene id: 645517:A6F65_RS00465
uniprot id: A0A1C7D4Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

645517:A6F65 RS07480
gene id: 645517:A6F65_RS07480
uniprot id: A0A1C7D8M0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06260
gene id: 645517:A6F65_RS06260
uniprot id: A0A1C7D8A0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

645517:A6F65 RS10425
gene id: 645517:A6F65_RS10425
uniprot id: A0A1C7DAE8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

645517:A6F65 RS05430
gene id: 645517:A6F65_RS05430
uniprot id: A0A1C7D7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS02375
gene id: 645517:A6F65_RS02375
uniprot id: A0A1C7D5P0
names: Similarity
messages: Belongs to the GARS family.

645517:A6F65 RS00450
gene id: 645517:A6F65_RS00450
uniprot id: A0A1C7D4P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645517:A6F65 RS06860
gene id: 645517:A6F65_RS06860
uniprot id: A0A1C7D8D5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

645517:A6F65 RS05900
gene id: 645517:A6F65_RS05900
uniprot id: A0A1C7D7T5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS07970
gene id: 645517:A6F65_RS07970
uniprot id: A0A1C7D903
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

645517:A6F65 RS06540
gene id: 645517:A6F65_RS06540
uniprot id: A0A1C7D831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

645517:A6F65 RS09450
gene id: 645517:A6F65_RS09450
uniprot id: A0A1C7D9V8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

645517:A6F65 RS12115
gene id: 645517:A6F65_RS12115
uniprot id: A0A1C7DBU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

645517:A6F65 RS03990
gene id: 645517:A6F65_RS03990
uniprot id: A0A1C7D6P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

645517:A6F65 RS00185
gene id: 645517:A6F65_RS00185
uniprot id: A0A1C7D4H6
names: Similarity
messages: Belongs to the PrpD family.

645517:A6F65 RS11980
gene id: 645517:A6F65_RS11980
uniprot id: A0A1C7DB87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

645517:A6F65 RS09220
gene id: 645517:A6F65_RS09220
uniprot id: A0A1C7D9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

645517:A6F65 RS06195
gene id: 645517:A6F65_RS06195
uniprot id: A0A1C7D7W1
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

645517:A6F65 RS09210
gene id: 645517:A6F65_RS09210
uniprot id: A0A1C7D9P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS02220
gene id: 645517:A6F65_RS02220
uniprot id: A0A1C7D5M7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

645517:A6F65 RS10135
gene id: 645517:A6F65_RS10135
uniprot id: A0A1C7DA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

645517:A6F65 RS03240
gene id: 645517:A6F65_RS03240
uniprot id: A0A1C7D695
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

645517:A6F65 RS09495
gene id: 645517:A6F65_RS09495
uniprot id: A0A1C7D9T1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

645517:A6F65 RS08655
gene id: 645517:A6F65_RS08655
uniprot id: A0A1C7D9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

645517:A6F65 RS04975
gene id: 645517:A6F65_RS04975
uniprot id: A0A1C7D7Q1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

645517:A6F65 RS01710
gene id: 645517:A6F65_RS01710
uniprot id: A0A1C7D5P2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

645517:A6F65 RS04125
gene id: 645517:A6F65_RS04125
uniprot id: A0A1C7D6P1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

645517:A6F65 RS07360
gene id: 645517:A6F65_RS07360
uniprot id: A0A1C7D8J3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

645517:A6F65 RS06460
gene id: 645517:A6F65_RS06460
uniprot id: A0A1C7D823
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

645517:A6F65 RS12015
gene id: 645517:A6F65_RS12015
uniprot id: A0A1C7DBG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

645517:A6F65 RS10235
gene id: 645517:A6F65_RS10235
uniprot id: A0A1C7DA91
names: Similarity
messages: Belongs to the SAICAR synthetase family.

645517:A6F65 RS01655
gene id: 645517:A6F65_RS01655
uniprot id: A0A1C7D5Q7
names: Subunit
messages: Homotetramer.

645517:A6F65 RS11470
gene id: 645517:A6F65_RS11470
uniprot id: A0A1C7DAY7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

645517:A6F65 RS08920
gene id: 645517:A6F65_RS08920
uniprot id: A0A1C7D9F2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS04115
gene id: 645517:A6F65_RS04115
uniprot id: A0A1C7D6R9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

645517:A6F65 RS04540
gene id: 645517:A6F65_RS04540
uniprot id: A0A1C7D798
names: Similarity
messages: Belongs to the Dps family.

645517:A6F65 RS02100
gene id: 645517:A6F65_RS02100
uniprot id: A0A1C7D5K6
names: Similarity
messages: Belongs to the glutamate synthase family.

645517:A6F65 RS11790
gene id: 645517:A6F65_RS11790
uniprot id: A0A1C7DB13
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

645517:A6F65 RS06245
gene id: 645517:A6F65_RS06245
uniprot id: A0A1C7D7X5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

645517:A6F65 RS01135
gene id: 645517:A6F65_RS01135
uniprot id: A0A1C7D507
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS03080
gene id: 645517:A6F65_RS03080
uniprot id: A0A1C7D665
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

645517:A6F65 RS11405
gene id: 645517:A6F65_RS11405
uniprot id: A0A1C7DBE0
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS09560
gene id: 645517:A6F65_RS09560
uniprot id: A0A1C7D9S3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS07140
gene id: 645517:A6F65_RS07140
uniprot id: A0A1C7D8F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

645517:A6F65 RS11050
gene id: 645517:A6F65_RS11050
uniprot id: A0A1C7DAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

645517:A6F65 RS11150
gene id: 645517:A6F65_RS11150
uniprot id: A0A1C7DAZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

645517:A6F65 RS00590
gene id: 645517:A6F65_RS00590
uniprot id: A0A1C7D4Q7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS05855
gene id: 645517:A6F65_RS05855
uniprot id: A0A1C7D7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

645517:A6F65 RS00095
gene id: 645517:A6F65_RS00095
uniprot id: A0A1C7D4G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

645517:A6F65 RS07325
gene id: 645517:A6F65_RS07325
uniprot id: A0A1C7D8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

645517:A6F65 RS11645
gene id: 645517:A6F65_RS11645
uniprot id: A0A1C7DAX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

645517:A6F65 RS12520
gene id: 645517:A6F65_RS12520
uniprot id: A0A1C7DBE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

645517:A6F65 RS07135
gene id: 645517:A6F65_RS07135
uniprot id: A0A1C7D8H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

645517:A6F65 RS06015
gene id: 645517:A6F65_RS06015
uniprot id: A0A1C7D844
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

645517:A6F65 RS10780
gene id: 645517:A6F65_RS10780
uniprot id: A0A1C7DAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

645517:A6F65 RS01850
gene id: 645517:A6F65_RS01850
uniprot id: A0A1C7D5F4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

645517:A6F65 RS04880
gene id: 645517:A6F65_RS04880
uniprot id: A0A1C7D751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

645517:A6F65 RS05765
gene id: 645517:A6F65_RS05765
uniprot id: A0A1C7D837
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS00060
gene id: 645517:A6F65_RS00060
uniprot id: A0A1C7D4F9
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS05435
gene id: 645517:A6F65_RS05435
uniprot id: A0A1C7D7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

645517:A6F65 RS09545
gene id: 645517:A6F65_RS09545
uniprot id: A0A1C7DAA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS08890
gene id: 645517:A6F65_RS08890
uniprot id: A0A1C7D9G0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

645517:A6F65 RS08925
gene id: 645517:A6F65_RS08925
uniprot id: A0A1C7D9W6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

645517:A6F65 RS08885
gene id: 645517:A6F65_RS08885
uniprot id: A0A1C7D9V7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

645517:A6F65 RS08005
gene id: 645517:A6F65_RS08005
uniprot id: A0A1C7D8X0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

645517:A6F65 RS06545
gene id: 645517:A6F65_RS06545
uniprot id: A0A1C7D8J2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

645517:A6F65 RS07300
gene id: 645517:A6F65_RS07300
uniprot id: A0A1C7D8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

645517:A6F65 RS11350
gene id: 645517:A6F65_RS11350
uniprot id: A0A1C7DB39
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

645517:A6F65 RS03715
gene id: 645517:A6F65_RS03715
uniprot id: A0A1C7D6J0
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

645517:A6F65 RS11965
gene id: 645517:A6F65_RS11965
uniprot id: A0A1C7DBF2
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

645517:A6F65 RS09440
gene id: 645517:A6F65_RS09440
uniprot id: A0A1C7DA88
names: Similarity
messages: Belongs to the DprA/Smf family.

645517:A6F65 RS03770
gene id: 645517:A6F65_RS03770
uniprot id: A0A1C7D6H1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

645517:A6F65 RS06405
gene id: 645517:A6F65_RS06405
uniprot id: A0A1C7D8J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

645517:A6F65 RS01830
gene id: 645517:A6F65_RS01830
uniprot id: A0A1C7D5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

645517:A6F65 RS08460
gene id: 645517:A6F65_RS08460
uniprot id: A0A1C7D964
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS00190
gene id: 645517:A6F65_RS00190
uniprot id: A0A1C7D4I3
names: Similarity
messages: Belongs to the PrpD family.

645517:A6F65 RS06785
gene id: 645517:A6F65_RS06785
uniprot id: A0A1C7D887
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

645517:A6F65 RS11510
gene id: 645517:A6F65_RS11510
uniprot id: A0A1C7DBG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

645517:A6F65 RS00680
gene id: 645517:A6F65_RS00680
uniprot id: A0A1C7D4S3
names: Similarity
messages: Belongs to the GcvT family.

645517:A6F65 RS03700
gene id: 645517:A6F65_RS03700
uniprot id: A0A1C7D6U3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

645517:A6F65 RS03480
gene id: 645517:A6F65_RS03480
uniprot id: A0A1C7D6E8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS01380
gene id: 645517:A6F65_RS01380
uniprot id: A0A1C7D556
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

645517:A6F65 RS03005
gene id: 645517:A6F65_RS03005
uniprot id: A0A1C7D6E6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS12045
gene id: 645517:A6F65_RS12045
uniprot id: A0A1C7DB96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

645517:A6F65 RS11300
gene id: 645517:A6F65_RS11300
uniprot id: A0A1C7DB22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

645517:A6F65 RS00220
gene id: 645517:A6F65_RS00220
uniprot id: A0A1C7D4Y9
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

645517:A6F65 RS00105
gene id: 645517:A6F65_RS00105
uniprot id: A0A1C7D4H4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

645517:A6F65 RS02305
gene id: 645517:A6F65_RS02305
uniprot id: A0A1C7D634
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

645517:A6F65 RS03510
gene id: 645517:A6F65_RS03510
uniprot id: A0A1C7D6E9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

645517:A6F65 RS11215
gene id: 645517:A6F65_RS11215
uniprot id: A0A1C7DAU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

645517:A6F65 RS05660
gene id: 645517:A6F65_RS05660
uniprot id: A0A1C7D7K5
names: Similarity
messages: Belongs to the BolA/IbaG family.

645517:A6F65 RS04000
gene id: 645517:A6F65_RS04000
uniprot id: A0A1C7D731
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

645517:A6F65 RS07840
gene id: 645517:A6F65_RS07840
uniprot id: A0A1C7D953
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06300
gene id: 645517:A6F65_RS06300
uniprot id: A0A1C7D7Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS02525
gene id: 645517:A6F65_RS02525
uniprot id: A0A1C7D5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

645517:A6F65 RS00510
gene id: 645517:A6F65_RS00510
uniprot id: A0A1C7D527
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS11495
gene id: 645517:A6F65_RS11495
uniprot id: A0A1C7DAV0
names: Similarity
messages: Belongs to the NTE family.

645517:A6F65 RS06645
gene id: 645517:A6F65_RS06645
uniprot id: A0A1C7D8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

645517:A6F65 RS06755
gene id: 645517:A6F65_RS06755
uniprot id: A0A1C7D8R2
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

645517:A6F65 RS11110
gene id: 645517:A6F65_RS11110
uniprot id: A0A1C7DAR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07105
gene id: 645517:A6F65_RS07105
uniprot id: A0A1C7D8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

645517:A6F65 RS04490
gene id: 645517:A6F65_RS04490
uniprot id: A0A1C7D790
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

645517:A6F65 RS10915
gene id: 645517:A6F65_RS10915
uniprot id: A0A1C7DAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

645517:A6F65 RS00275
gene id: 645517:A6F65_RS00275
uniprot id: A0A1C7D4K2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS05645
gene id: 645517:A6F65_RS05645
uniprot id: A0A1C7D7P4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

645517:A6F65 RS09315
gene id: 645517:A6F65_RS09315
uniprot id: A0A1C7D9R4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

645517:A6F65 RS06690
gene id: 645517:A6F65_RS06690
uniprot id: A0A1C7D861
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

645517:A6F65 RS10725
gene id: 645517:A6F65_RS10725
uniprot id: A0A1C7DAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

645517:A6F65 RS05675
gene id: 645517:A6F65_RS05675
uniprot id: A0A1C7D847
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

645517:A6F65 RS09125
gene id: 645517:A6F65_RS09125
uniprot id: A0A1C7DA10
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

645517:A6F65 RS05490
gene id: 645517:A6F65_RS05490
uniprot id: A0A1C7D7L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

645517:A6F65 RS06475
gene id: 645517:A6F65_RS06475
uniprot id: A0A1C7D858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

645517:A6F65 RS03370
gene id: 645517:A6F65_RS03370
uniprot id: A0A1C7D685
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

645517:A6F65 RS05040
gene id: 645517:A6F65_RS05040
uniprot id: A0A1C7D7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

645517:A6F65 RS00820
gene id: 645517:A6F65_RS00820
uniprot id: A0A1C7D5B5
names: Similarity
messages: Belongs to the aspartokinase family.

645517:A6F65 RS00405
gene id: 645517:A6F65_RS00405
uniprot id: A0A1C7D4M7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

645517:A6F65 RS09455
gene id: 645517:A6F65_RS09455
uniprot id: A0A1C7D9P5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

645517:A6F65 RS01900
gene id: 645517:A6F65_RS01900
uniprot id: A0A1C7D5G4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

645517:A6F65 RS07720
gene id: 645517:A6F65_RS07720
uniprot id: A0A1C7D8R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

645517:A6F65 RS02115
gene id: 645517:A6F65_RS02115
uniprot id: A0A1C7D617
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS12180
gene id: 645517:A6F65_RS12180
uniprot id: A0A1C7DB93
names: Similarity
messages: Belongs to the ArsC family.

645517:A6F65 RS00285
gene id: 645517:A6F65_RS00285
uniprot id: A0A1C7D4J1
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

645517:A6F65 RS11505
gene id: 645517:A6F65_RS11505
uniprot id: A0A1C7DB66
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

645517:A6F65 RS07780
gene id: 645517:A6F65_RS07780
uniprot id: A0A1C7D988
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

645517:A6F65 RS00040
gene id: 645517:A6F65_RS00040
uniprot id: A0A1C7D4E5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

645517:A6F65 RS01855
gene id: 645517:A6F65_RS01855
uniprot id: A0A1C7D5U3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

645517:A6F65 RS01125
gene id: 645517:A6F65_RS01125
uniprot id: A0A1C7D511
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645517:A6F65 RS08650
gene id: 645517:A6F65_RS08650
uniprot id: A0A1C7D9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

645517:A6F65 RS03115
gene id: 645517:A6F65_RS03115
uniprot id: A0A1C7D667
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

645517:A6F65 RS07290
gene id: 645517:A6F65_RS07290
uniprot id: A0A1C7D8L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

645517:A6F65 RS06895
gene id: 645517:A6F65_RS06895
uniprot id: A0A1C7D8M6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

645517:A6F65 RS11695
gene id: 645517:A6F65_RS11695
uniprot id: A0A1C7DAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

645517:A6F65 RS11460
gene id: 645517:A6F65_RS11460
uniprot id: A0A1C7DAY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

645517:A6F65 RS09295
gene id: 645517:A6F65_RS09295
uniprot id: A0A1C7D9P1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

645517:A6F65 RS11335
gene id: 645517:A6F65_RS11335
uniprot id: A0A1C7DAR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

645517:A6F65 RS06790
gene id: 645517:A6F65_RS06790
uniprot id: A0A1C7D881
names: Similarity
messages: Belongs to the virb1 family.

645517:A6F65 RS08215
gene id: 645517:A6F65_RS08215
uniprot id: A0A1C7D8Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS03910
gene id: 645517:A6F65_RS03910
uniprot id: A0A1C7D6M7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS05630
gene id: 645517:A6F65_RS05630
uniprot id: A0A1C7D7J8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

645517:A6F65 RS11325
gene id: 645517:A6F65_RS11325
uniprot id: A0A1C7DAZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

645517:A6F65 RS00090
gene id: 645517:A6F65_RS00090
uniprot id: A0A1C7D4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

645517:A6F65 RS06440
gene id: 645517:A6F65_RS06440
uniprot id: A0A1C7D811
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

645517:A6F65 RS10935
gene id: 645517:A6F65_RS10935
uniprot id: A0A1C7DB12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS10140
gene id: 645517:A6F65_RS10140
uniprot id: A0A1C7DA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

645517:A6F65 RS10735
gene id: 645517:A6F65_RS10735
uniprot id: A0A1C7DAE2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

645517:A6F65 RS04035
gene id: 645517:A6F65_RS04035
uniprot id: A0A1C7D6R0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

645517:A6F65 RS03100
gene id: 645517:A6F65_RS03100
uniprot id: A0A1C7D6J4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

645517:A6F65 RS03450
gene id: 645517:A6F65_RS03450
uniprot id: A0A1C7D6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS01390
gene id: 645517:A6F65_RS01390
uniprot id: A0A1C7D578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

645517:A6F65 RS12480
gene id: 645517:A6F65_RS12480
uniprot id: A0A1C7DBI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

645517:A6F65 RS06065
gene id: 645517:A6F65_RS06065
uniprot id: A0A1C7D8D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

645517:A6F65 RS07255
gene id: 645517:A6F65_RS07255
uniprot id: A0A1C7D8H3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

645517:A6F65 RS09735
gene id: 645517:A6F65_RS09735
uniprot id: A0A1C7D9V5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

645517:A6F65 RS05550
gene id: 645517:A6F65_RS05550
uniprot id: A0A1C7D7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

645517:A6F65 RS05185
gene id: 645517:A6F65_RS05185
uniprot id: A0A1C7D7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

645517:A6F65 RS09610
gene id: 645517:A6F65_RS09610
uniprot id: A0A1C7D9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

645517:A6F65 RS04495
gene id: 645517:A6F65_RS04495
uniprot id: A0A1C7D7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS11400
gene id: 645517:A6F65_RS11400
uniprot id: A0A1C7DB50
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS02815
gene id: 645517:A6F65_RS02815
uniprot id: A0A1C7D610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS04695
gene id: 645517:A6F65_RS04695
uniprot id: A0A1C7D734
names: Similarity
messages: Belongs to the UPF0178 family.

645517:A6F65 RS11555
gene id: 645517:A6F65_RS11555
uniprot id: A0A1C7DBH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

645517:A6F65 RS07630
gene id: 645517:A6F65_RS07630
uniprot id: A0A1C7D916
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

645517:A6F65 RS06180
gene id: 645517:A6F65_RS06180
uniprot id: A0A1C7D7Z7
names: Similarity
messages: Belongs to the ros/MucR family.

645517:A6F65 RS03440
gene id: 645517:A6F65_RS03440
uniprot id: A0A1C7D6R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

645517:A6F65 RS06240
gene id: 645517:A6F65_RS06240
uniprot id: A0A1C7D7Z4
names: Similarity
messages: Belongs to the GST superfamily.

645517:A6F65 RS06570
gene id: 645517:A6F65_RS06570
uniprot id: A0A1C7D830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

645517:A6F65 RS02515
gene id: 645517:A6F65_RS02515
uniprot id: A0A1C7D698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

645517:A6F65 RS11065
gene id: 645517:A6F65_RS11065
uniprot id: A0A1C7DAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

645517:A6F65 RS02550
gene id: 645517:A6F65_RS02550
uniprot id: A0A1C7D5U9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

645517:A6F65 RS08750
gene id: 645517:A6F65_RS08750
uniprot id: A0A1C7D9T8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

645517:A6F65 RS10225
gene id: 645517:A6F65_RS10225
uniprot id: A0A1C7DA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS05625
gene id: 645517:A6F65_RS05625
uniprot id: A0A1C7D836
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

645517:A6F65 RS06490
gene id: 645517:A6F65_RS06490
uniprot id: A0A1C7D822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

645517:A6F65 RS01185
gene id: 645517:A6F65_RS01185
uniprot id: A0A1C7D518
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

645517:A6F65 RS08420
gene id: 645517:A6F65_RS08420
uniprot id: A0A1C7D943
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

645517:A6F65 RS08375
gene id: 645517:A6F65_RS08375
uniprot id: A0A1C7D979
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

645517:A6F65 RS05440
gene id: 645517:A6F65_RS05440
uniprot id: A0A1C7D7K1
names: Similarity
messages: Belongs to the threonine synthase family.

645517:A6F65 RS12620
gene id: 645517:A6F65_RS12620
uniprot id: A0A1C7DBG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

645517:A6F65 RS01880
gene id: 645517:A6F65_RS01880
uniprot id: A0A1C7D5E8
names: Similarity
messages: Belongs to the peptidase S41A family.

645517:A6F65 RS03815
gene id: 645517:A6F65_RS03815
uniprot id: A0A1C7D6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

645517:A6F65 RS08400
gene id: 645517:A6F65_RS08400
uniprot id: A0A1C7D9F7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

645517:A6F65 RS12195
gene id: 645517:A6F65_RS12195
uniprot id: A0A1C7DB95
names: Function
messages: Multidrug efflux pump.

645517:A6F65 RS05815
gene id: 645517:A6F65_RS05815
uniprot id: A0A1C7D849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

645517:A6F65 RS06595
gene id: 645517:A6F65_RS06595
uniprot id: A0A1C7D8K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

645517:A6F65 RS00025
gene id: 645517:A6F65_RS00025
uniprot id: A0A1C7D4V6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

645517:A6F65 RS07190
gene id: 645517:A6F65_RS07190
uniprot id: A0A1C7D8I8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06420
gene id: 645517:A6F65_RS06420
uniprot id: A0A1C7D802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

645517:A6F65 RS08530
gene id: 645517:A6F65_RS08530
uniprot id: A0A1C7D968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

645517:A6F65 RS12565
gene id: 645517:A6F65_RS12565
uniprot id: A0A1C7DBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS00585
gene id: 645517:A6F65_RS00585
uniprot id: A0A1C7D4P4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS00335
gene id: 645517:A6F65_RS00335
uniprot id: A0A1C7D4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

645517:A6F65 RS10855
gene id: 645517:A6F65_RS10855
uniprot id: A0A1C7DAL6
names: Similarity
messages: Belongs to the sterol desaturase family.

645517:A6F65 RS03885
gene id: 645517:A6F65_RS03885
uniprot id: A0A1C7D6L7
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

645517:A6F65 RS05190
gene id: 645517:A6F65_RS05190
uniprot id: A0A1C7D7A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

645517:A6F65 RS05010
gene id: 645517:A6F65_RS05010
uniprot id: A0A1C7D785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

645517:A6F65 RS09995
gene id: 645517:A6F65_RS09995
uniprot id: A0A1C7DA37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

645517:A6F65 RS11795
gene id: 645517:A6F65_RS11795
uniprot id: A0A1C7DB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

645517:A6F65 RS10390
gene id: 645517:A6F65_RS10390
uniprot id: A0A1C7DAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

645517:A6F65 RS10745
gene id: 645517:A6F65_RS10745
uniprot id: A0A1C7DAX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

645517:A6F65 RS10845
gene id: 645517:A6F65_RS10845
uniprot id: A0A1C7DAT4
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

645517:A6F65 RS06155
gene id: 645517:A6F65_RS06155
uniprot id: A0A1C7D880
names: Similarity
messages: Belongs to the PhoH family.

645517:A6F65 RS10200
gene id: 645517:A6F65_RS10200
uniprot id: A0A1C7DAM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

645517:A6F65 RS02605
gene id: 645517:A6F65_RS02605
uniprot id: A0A1C7D5W8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

645517:A6F65 RS08760
gene id: 645517:A6F65_RS08760
uniprot id: A0A1C7D9G6
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00315
gene id: 645517:A6F65_RS00315
uniprot id: A0A1C7D4V8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

645517:A6F65 RS05690
gene id: 645517:A6F65_RS05690
uniprot id: A0A1C7D7J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS11815
gene id: 645517:A6F65_RS11815
uniprot id: A0A1C7DBM7
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

645517:A6F65 RS01395
gene id: 645517:A6F65_RS01395
uniprot id: A0A1C7D569
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

645517:A6F65 RS03310
gene id: 645517:A6F65_RS03310
uniprot id: A0A1C7D6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

645517:A6F65 RS10105
gene id: 645517:A6F65_RS10105
uniprot id: A0A1C7DAE6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

645517:A6F65 RS12435
gene id: 645517:A6F65_RS12435
uniprot id: A0A1C7DBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

645517:A6F65 RS07130
gene id: 645517:A6F65_RS07130
uniprot id: A0A1C7D8I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

645517:A6F65 RS04525
gene id: 645517:A6F65_RS04525
uniprot id: A0A1C7D6Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

645517:A6F65 RS08160
gene id: 645517:A6F65_RS08160
uniprot id: A0A1C7D900
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

645517:A6F65 RS09665
gene id: 645517:A6F65_RS09665
uniprot id: A0A1C7D9Z9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS10740
gene id: 645517:A6F65_RS10740
uniprot id: A0A1C7DAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS01575
gene id: 645517:A6F65_RS01575
uniprot id: A0A1C7D588
names: Similarity
messages: Belongs to the GcvT family.

645517:A6F65 RS01485
gene id: 645517:A6F65_RS01485
uniprot id: A0A1C7D593
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

645517:A6F65 RS00980
gene id: 645517:A6F65_RS00980
uniprot id: A0A1C7D4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

645517:A6F65 RS01155
gene id: 645517:A6F65_RS01155
uniprot id: A0A1C7D5G0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

645517:A6F65 RS10420
gene id: 645517:A6F65_RS10420
uniprot id: A0A1C7DAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS08305
gene id: 645517:A6F65_RS08305
uniprot id: A0A1C7D9K3
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS04045
gene id: 645517:A6F65_RS04045
uniprot id: A0A1C7D6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

645517:A6F65 RS08540
gene id: 645517:A6F65_RS08540
uniprot id: A0A1C7D9P4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

645517:A6F65 RS00945
gene id: 645517:A6F65_RS00945
uniprot id: A0A1C7D4Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

645517:A6F65 RS08265
gene id: 645517:A6F65_RS08265
uniprot id: A0A1C7D966
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

645517:A6F65 RS04830
gene id: 645517:A6F65_RS04830
uniprot id: A0A1C7D7L7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

645517:A6F65 RS09530
gene id: 645517:A6F65_RS09530
uniprot id: A0A1C7D9R6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

645517:A6F65 RS07095
gene id: 645517:A6F65_RS07095
uniprot id: A0A1C7D8V5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

645517:A6F65 RS07075
gene id: 645517:A6F65_RS07075
uniprot id: A0A1C7D8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

645517:A6F65 RS12590
gene id: 645517:A6F65_RS12590
uniprot id: A0A1C7DBK7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS04835
gene id: 645517:A6F65_RS04835
uniprot id: A0A1C7D735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

645517:A6F65 RS09115
gene id: 645517:A6F65_RS09115
uniprot id: A0A1C7D9I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS09445
gene id: 645517:A6F65_RS09445
uniprot id: A0A1C7D9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

645517:A6F65 RS02965
gene id: 645517:A6F65_RS02965
uniprot id: A0A1C7D6J2
names: Similarity
messages: Belongs to the glutamate synthase family.

645517:A6F65 RS06125
gene id: 645517:A6F65_RS06125
uniprot id: A0A1C7D7Y3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

645517:A6F65 RS04840
gene id: 645517:A6F65_RS04840
uniprot id: A0A1C7D767
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

645517:A6F65 RS00860
gene id: 645517:A6F65_RS00860
uniprot id: A0A1C7D5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

645517:A6F65 RS08855
gene id: 645517:A6F65_RS08855
uniprot id: A0A1C7D9E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

645517:A6F65 RS03070
gene id: 645517:A6F65_RS03070
uniprot id: A0A1C7D660
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

645517:A6F65 RS10460
gene id: 645517:A6F65_RS10460
uniprot id: A0A1C7DAK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645517:A6F65 RS08055
gene id: 645517:A6F65_RS08055
uniprot id: A0A1C7D8Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

645517:A6F65 RS12970
gene id: 645517:A6F65_RS12970
uniprot id: A0A1C7DAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

645517:A6F65 RS06450
gene id: 645517:A6F65_RS06450
uniprot id: A0A1C7D8E0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

645517:A6F65 RS00915
gene id: 645517:A6F65_RS00915
uniprot id: A0A1C7D577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645517:A6F65 RS06030
gene id: 645517:A6F65_RS06030
uniprot id: A0A1C7D7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

645517:A6F65 RS07935
gene id: 645517:A6F65_RS07935
uniprot id: A0A1C7D8V3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06830
gene id: 645517:A6F65_RS06830
uniprot id: A0A1C7D8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

645517:A6F65 RS03730
gene id: 645517:A6F65_RS03730
uniprot id: A0A1C7D6J7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

645517:A6F65 RS02120
gene id: 645517:A6F65_RS02120
uniprot id: A0A1C7D5K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

645517:A6F65 RS09355
gene id: 645517:A6F65_RS09355
uniprot id: A0A1C7D9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

645517:A6F65 RS00940
gene id: 645517:A6F65_RS00940
uniprot id: A0A1C7D4W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

645517:A6F65 RS07280
gene id: 645517:A6F65_RS07280
uniprot id: A0A1C7D8L6
names: Similarity
messages: Belongs to the fabD family.

645517:A6F65 RS02145
gene id: 645517:A6F65_RS02145
uniprot id: A0A1C7D5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

645517:A6F65 RS06455
gene id: 645517:A6F65_RS06455
uniprot id: A0A1C7D8K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

645517:A6F65 RS07455
gene id: 645517:A6F65_RS07455
uniprot id: A0A1C7D8L3
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08715
gene id: 645517:A6F65_RS08715
uniprot id: A0A1C7D999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

645517:A6F65 RS05535
gene id: 645517:A6F65_RS05535
uniprot id: A0A1C7D7L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

645517:A6F65 RS12050
gene id: 645517:A6F65_RS12050
uniprot id: A0A1C7DB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

645517:A6F65 RS08230
gene id: 645517:A6F65_RS08230
uniprot id: A0A1C7D910
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

645517:A6F65 RS03610
gene id: 645517:A6F65_RS03610
uniprot id: A0A1C7D6H2
names: Similarity
messages: Belongs to the cytochrome P450 family.

645517:A6F65 RS12555
gene id: 645517:A6F65_RS12555
uniprot id: A0A1C7DBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

645517:A6F65 RS11430
gene id: 645517:A6F65_RS11430
uniprot id: A0A1C7DAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

645517:A6F65 RS06430
gene id: 645517:A6F65_RS06430
uniprot id: A0A1C7D835
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

645517:A6F65 RS02065
gene id: 645517:A6F65_RS02065
uniprot id: A0A1C7D607
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

645517:A6F65 RS09370
gene id: 645517:A6F65_RS09370
uniprot id: A0A1C7D9M5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS01430
gene id: 645517:A6F65_RS01430
uniprot id: A0A1C7D573
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

645517:A6F65 RS04140
gene id: 645517:A6F65_RS04140
uniprot id: A0A1C7D6R5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

645517:A6F65 RS03415
gene id: 645517:A6F65_RS03415
uniprot id: A0A1C7D697
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

645517:A6F65 RS08080
gene id: 645517:A6F65_RS08080
uniprot id: A0A1C7D907
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

645517:A6F65 RS11305
gene id: 645517:A6F65_RS11305
uniprot id: A0A1C7DBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

645517:A6F65 RS03525
gene id: 645517:A6F65_RS03525
uniprot id: A0A1C7D6E7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

645517:A6F65 RS06305
gene id: 645517:A6F65_RS06305
uniprot id: A0A1C7D8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

645517:A6F65 RS08475
gene id: 645517:A6F65_RS08475
uniprot id: A0A1C7D9A3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

645517:A6F65 RS03155
gene id: 645517:A6F65_RS03155
uniprot id: A0A1C7D6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

645517:A6F65 RS07945
gene id: 645517:A6F65_RS07945
uniprot id: A0A1C7D973
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

645517:A6F65 RS05105
gene id: 645517:A6F65_RS05105
uniprot id: A0A1C7D7C5
names: Similarity
messages: Belongs to the HIBADH-related family.

645517:A6F65 RS09395
gene id: 645517:A6F65_RS09395
uniprot id: A0A1C7D9R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

645517:A6F65 RS08985
gene id: 645517:A6F65_RS08985
uniprot id: A0A1C7D9Y6
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS06400
gene id: 645517:A6F65_RS06400
uniprot id: A0A1C7D8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

645517:A6F65 RS09885
gene id: 645517:A6F65_RS09885
uniprot id: A0A1C7DA17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

645517:A6F65 RS06965
gene id: 645517:A6F65_RS06965
uniprot id: A0A1C7D8F6
names: Similarity
messages: Belongs to the Gfa family.

645517:A6F65 RS11960
gene id: 645517:A6F65_RS11960
uniprot id: A0A1C7DBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

645517:A6F65 RS09390
gene id: 645517:A6F65_RS09390
uniprot id: A0A1C7DA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

645517:A6F65 RS07725
gene id: 645517:A6F65_RS07725
uniprot id: A0A1C7D8R5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00660
gene id: 645517:A6F65_RS00660
uniprot id: A0A1C7D559
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS09405
gene id: 645517:A6F65_RS09405
uniprot id: A0A1C7D9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

645517:A6F65 RS11290
gene id: 645517:A6F65_RS11290
uniprot id: A0A1C7DAQ6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

645517:A6F65 RS09680
gene id: 645517:A6F65_RS09680
uniprot id: A0A1C7D9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

645517:A6F65 RS01760
gene id: 645517:A6F65_RS01760
uniprot id: A0A1C7D5P9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

645517:A6F65 RS09150
gene id: 645517:A6F65_RS09150
uniprot id: A0A1C7D9J0
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS02180
gene id: 645517:A6F65_RS02180
uniprot id: A0A1C7D5K4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

645517:A6F65 RS11090
gene id: 645517:A6F65_RS11090
uniprot id: A0A1C7DAL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

645517:A6F65 RS02320
gene id: 645517:A6F65_RS02320
uniprot id: A0A1C7D5Q6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

645517:A6F65 RS11375
gene id: 645517:A6F65_RS11375
uniprot id: A0A1C7DB07
names: Similarity
messages: Belongs to the peptidase A24 family.

645517:A6F65 RS05545
gene id: 645517:A6F65_RS05545
uniprot id: A0A1C7D7M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

645517:A6F65 RS04945
gene id: 645517:A6F65_RS04945
uniprot id: A0A1C7D781
names: Subunit
messages: Homodimer.

645517:A6F65 RS09645
gene id: 645517:A6F65_RS09645
uniprot id: A0A1C7DAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

645517:A6F65 RS06675
gene id: 645517:A6F65_RS06675
uniprot id: A0A1C7D894
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

645517:A6F65 RS01935
gene id: 645517:A6F65_RS01935
uniprot id: A0A1C7D5H8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

645517:A6F65 RS10960
gene id: 645517:A6F65_RS10960
uniprot id: A0A1C7DAK1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

645517:A6F65 RS03645
gene id: 645517:A6F65_RS03645
uniprot id: A0A1C7D6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS12220
gene id: 645517:A6F65_RS12220
uniprot id: A0A1C7DBE3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

645517:A6F65 RS08225
gene id: 645517:A6F65_RS08225
uniprot id: A0A1C7D937
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

645517:A6F65 RS11550
gene id: 645517:A6F65_RS11550
uniprot id: A0A1C7DB77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

645517:A6F65 RS01805
gene id: 645517:A6F65_RS01805
uniprot id: A0A1C7D5T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06585
gene id: 645517:A6F65_RS06585
uniprot id: A0A1C7D843
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

645517:A6F65 RS02080
gene id: 645517:A6F65_RS02080
uniprot id: A0A1C7D5I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

645517:A6F65 RS11640
gene id: 645517:A6F65_RS11640
uniprot id: A0A1C7DAY0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

645517:A6F65 RS12130
gene id: 645517:A6F65_RS12130
uniprot id: A0A1C7DB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

645517:A6F65 RS08255
gene id: 645517:A6F65_RS08255
uniprot id: A0A1C7D9J1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

645517:A6F65 RS02075
gene id: 645517:A6F65_RS02075
uniprot id: A0A1C7D5L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

645517:A6F65 RS03180
gene id: 645517:A6F65_RS03180
uniprot id: A0A1C7D686
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

645517:A6F65 RS10910
gene id: 645517:A6F65_RS10910
uniprot id: A0A1C7DAM7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS01875
gene id: 645517:A6F65_RS01875
uniprot id: A0A1C7D5G7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS09740
gene id: 645517:A6F65_RS09740
uniprot id: A0A1C7DAC6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

645517:A6F65 RS00520
gene id: 645517:A6F65_RS00520
uniprot id: A0A1C7D551
names: Similarity
messages: Belongs to the GcvT family.

645517:A6F65 RS05030
gene id: 645517:A6F65_RS05030
uniprot id: A0A1C7D7R1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

645517:A6F65 RS09960
gene id: 645517:A6F65_RS09960
uniprot id: A0A1C7DAG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

645517:A6F65 RS05225
gene id: 645517:A6F65_RS05225
uniprot id: A0A1C7D7V1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

645517:A6F65 RS01475
gene id: 645517:A6F65_RS01475
uniprot id: A0A1C7D572
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

645517:A6F65 RS09065
gene id: 645517:A6F65_RS09065
uniprot id: A0A1C7D9H4
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS01460
gene id: 645517:A6F65_RS01460
uniprot id: A0A1C7D5P5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645517:A6F65 RS01635
gene id: 645517:A6F65_RS01635
uniprot id: A0A1C7D5B1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

645517:A6F65 RS01015
gene id: 645517:A6F65_RS01015
uniprot id: A0A1C7D5F5
names: Similarity
messages: Belongs to the AAA ATPase family.

645517:A6F65 RS02450
gene id: 645517:A6F65_RS02450
uniprot id: A0A1C7D5T3
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

645517:A6F65 RS00570
gene id: 645517:A6F65_RS00570
uniprot id: A0A1C7D564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS05650
gene id: 645517:A6F65_RS05650
uniprot id: A0A1C7D7N2
names: Similarity
messages: Belongs to the pirin family.

645517:A6F65 RS08550
gene id: 645517:A6F65_RS08550
uniprot id: A0A1C7D9P6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

645517:A6F65 RS00310
gene id: 645517:A6F65_RS00310
uniprot id: A0A1C7D4Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

645517:A6F65 RS09195
gene id: 645517:A6F65_RS09195
uniprot id: A0A1C7D9Q9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

645517:A6F65 RS04145
gene id: 645517:A6F65_RS04145
uniprot id: A0A1C7D6S0
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS09595
gene id: 645517:A6F65_RS09595
uniprot id: A0A1C7D9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS04015
gene id: 645517:A6F65_RS04015
uniprot id: A0A1C7D6P5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

645517:A6F65 RS04965
gene id: 645517:A6F65_RS04965
uniprot id: A0A1C7D7N4
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS06135
gene id: 645517:A6F65_RS06135
uniprot id: A0A1C7D7X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS04535
gene id: 645517:A6F65_RS04535
uniprot id: A0A1C7D7C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645517:A6F65 RS12085
gene id: 645517:A6F65_RS12085
uniprot id: A0A1C7DB73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

645517:A6F65 RS00210
gene id: 645517:A6F65_RS00210
uniprot id: A0A1C7D4X1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645517:A6F65 RS05695
gene id: 645517:A6F65_RS05695
uniprot id: A0A1C7D7Q3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

645517:A6F65 RS08560
gene id: 645517:A6F65_RS08560
uniprot id: A0A1C7D9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives.
messages: Secreted

645517:A6F65 RS01555
gene id: 645517:A6F65_RS01555
uniprot id: A0A1C7D5K8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

645517:A6F65 RS00850
gene id: 645517:A6F65_RS00850
uniprot id: A0A1C7D4X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

645517:A6F65 RS10290
gene id: 645517:A6F65_RS10290
uniprot id: A0A1C7DA57
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

645517:A6F65 RS00705
gene id: 645517:A6F65_RS00705
uniprot id: A0A1C7D4U6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS11200
gene id: 645517:A6F65_RS11200
uniprot id: A0A1C7DB08
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

645517:A6F65 RS11345
gene id: 645517:A6F65_RS11345
uniprot id: A0A1C7DB97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

645517:A6F65 RS10020
gene id: 645517:A6F65_RS10020
uniprot id: A0A1C7DAJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

645517:A6F65 RS07565
gene id: 645517:A6F65_RS07565
uniprot id: A0A1C7D8N5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

645517:A6F65 RS03035
gene id: 645517:A6F65_RS03035
uniprot id: A0A1C7D652
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

645517:A6F65 RS04160
gene id: 645517:A6F65_RS04160
uniprot id: A0A1C7D738
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

645517:A6F65 RS03185
gene id: 645517:A6F65_RS03185
uniprot id: A0A1C7D679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

645517:A6F65 RS10975
gene id: 645517:A6F65_RS10975
uniprot id: A0A1C7DAP5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

645517:A6F65 RS07850
gene id: 645517:A6F65_RS07850
uniprot id: A0A1C7D8T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

645517:A6F65 RS01100
gene id: 645517:A6F65_RS01100
uniprot id: A0A1C7D509
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

645517:A6F65 RS04250
gene id: 645517:A6F65_RS04250
uniprot id: A0A1C7D6T9
names: Similarity
messages: Belongs to the FeoA family.

645517:A6F65 RS04500
gene id: 645517:A6F65_RS04500
uniprot id: A0A1C7D6W8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

645517:A6F65 RS05100
gene id: 645517:A6F65_RS05100
uniprot id: A0A1C7D7D3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

645517:A6F65 RS05895
gene id: 645517:A6F65_RS05895
uniprot id: A0A1C7D7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

645517:A6F65 RS03010
gene id: 645517:A6F65_RS03010
uniprot id: A0A1C7D6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

645517:A6F65 RS06850
gene id: 645517:A6F65_RS06850
uniprot id: A0A1C7D8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS05925
gene id: 645517:A6F65_RS05925
uniprot id: A0A1C7D7R3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

645517:A6F65 RS10840
gene id: 645517:A6F65_RS10840
uniprot id: A0A1C7DAZ1
names: Similarity
messages: Belongs to the SufE family.

645517:A6F65 RS09025
gene id: 645517:A6F65_RS09025
uniprot id: A0A1C7D9Z0
names: Similarity
messages: Belongs to the asparagine synthetase family.

645517:A6F65 RS04825
gene id: 645517:A6F65_RS04825
uniprot id: A0A1C7D7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

645517:A6F65 RS04430
gene id: 645517:A6F65_RS04430
uniprot id: A0A1C7D6W7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645517:A6F65 RS06600
gene id: 645517:A6F65_RS06600
uniprot id: A0A1C7D8H1
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

645517:A6F65 RS03575
gene id: 645517:A6F65_RS03575
uniprot id: A0A1C7D6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

645517:A6F65 RS00900
gene id: 645517:A6F65_RS00900
uniprot id: A0A1C7D4Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS07620
gene id: 645517:A6F65_RS07620
uniprot id: A0A1C7D8P5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS03955
gene id: 645517:A6F65_RS03955
uniprot id: A0A1C7D6Z4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

645517:A6F65 RS03235
gene id: 645517:A6F65_RS03235
uniprot id: A0A1C7D689
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

645517:A6F65 RS01790
gene id: 645517:A6F65_RS01790
uniprot id: A0A1C7D5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

645517:A6F65 RS07025
gene id: 645517:A6F65_RS07025
uniprot id: A0A1C7D8G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

645517:A6F65 RS09075
gene id: 645517:A6F65_RS09075
uniprot id: A0A1C7DA00
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

645517:A6F65 RS12410
gene id: 645517:A6F65_RS12410
uniprot id: A0A1C7DBC0
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

645517:A6F65 RS03615
gene id: 645517:A6F65_RS03615
uniprot id: A0A1C7D6D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

645517:A6F65 RS07490
gene id: 645517:A6F65_RS07490
uniprot id: A0A1C7D8K6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

645517:A6F65 RS03945
gene id: 645517:A6F65_RS03945
uniprot id: A0A1C7D6N4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

645517:A6F65 RS04860
gene id: 645517:A6F65_RS04860
uniprot id: A0A1C7D744
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

645517:A6F65 RS09650
gene id: 645517:A6F65_RS09650
uniprot id: A0A1C7D9W7
names: Similarity
messages: Belongs to the Skp family.

645517:A6F65 RS04135
gene id: 645517:A6F65_RS04135
uniprot id: A0A1C7D6S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

645517:A6F65 RS08955
gene id: 645517:A6F65_RS08955
uniprot id: A0A1C7D9L3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

645517:A6F65 RS07165
gene id: 645517:A6F65_RS07165
uniprot id: A0A1C7D8Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

645517:A6F65 RS08045
gene id: 645517:A6F65_RS08045
uniprot id: A0A1C7D994
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

645517:A6F65 RS11895
gene id: 645517:A6F65_RS11895
uniprot id: A0A1C7DB36
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

645517:A6F65 RS08290
gene id: 645517:A6F65_RS08290
uniprot id: A0A1C7D920
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS09895
gene id: 645517:A6F65_RS09895
uniprot id: A0A1C7D9Z1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

645517:A6F65 RS08500
gene id: 645517:A6F65_RS08500
uniprot id: A0A1C7D9H9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645517:A6F65 RS08405
gene id: 645517:A6F65_RS08405
uniprot id: A0A1C7D9M1
names: Similarity
messages: Belongs to the UPF0102 family.

645517:A6F65 RS01590
gene id: 645517:A6F65_RS01590
uniprot id: A0A1C7D5C3
names: Cofactor
messages: Can also use Mn(2+) ion.

645517:A6F65 RS12530
gene id: 645517:A6F65_RS12530
uniprot id: A0A1C7DBR2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS08495
gene id: 645517:A6F65_RS08495
uniprot id: A0A1C7D9N3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

645517:A6F65 RS10820
gene id: 645517:A6F65_RS10820
uniprot id: A0A1C7DAP2
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS01565
gene id: 645517:A6F65_RS01565
uniprot id: A0A1C7D5A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

645517:A6F65 RS04590
gene id: 645517:A6F65_RS04590
uniprot id: A0A1C7D7A7
names: Similarity
messages: Belongs to the lycopene cyclase family.

645517:A6F65 RS08620
gene id: 645517:A6F65_RS08620
uniprot id: A0A1C7D9D1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

645517:A6F65 RS07575
gene id: 645517:A6F65_RS07575
uniprot id: A0A1C7D905
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

645517:A6F65 RS02510
gene id: 645517:A6F65_RS02510
uniprot id: A0A1C7D675
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

645517:A6F65 RS11485
gene id: 645517:A6F65_RS11485
uniprot id: A0A1C7DAZ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

645517:A6F65 RS07440
gene id: 645517:A6F65_RS07440
uniprot id: A0A1C7D8J6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645517:A6F65 RS06145
gene id: 645517:A6F65_RS06145
uniprot id: A0A1C7D7U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

645517:A6F65 RS06285
gene id: 645517:A6F65_RS06285
uniprot id: A0A1C7D816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

645517:A6F65 RS11175
gene id: 645517:A6F65_RS11175
uniprot id: A0A1C7DAW2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

645517:A6F65 RS10355
gene id: 645517:A6F65_RS10355
uniprot id: A0A1C7DAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

645517:A6F65 RS09700
gene id: 645517:A6F65_RS09700
uniprot id: A0A1C7D9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

645517:A6F65 RS11660
gene id: 645517:A6F65_RS11660
uniprot id: A0A1C7DBJ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645517:A6F65 RS03095
gene id: 645517:A6F65_RS03095
uniprot id: A0A1C7D670
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

645517:A6F65 RS12055
gene id: 645517:A6F65_RS12055
uniprot id: A0A1C7DB51
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

645517:A6F65 RS03425
gene id: 645517:A6F65_RS03425
uniprot id: A0A1C7D6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

645517:A6F65 RS03585
gene id: 645517:A6F65_RS03585
uniprot id: A0A1C7D6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

645517:A6F65 RS01895
gene id: 645517:A6F65_RS01895
uniprot id: A0A1C7D5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

645517:A6F65 RS11045
gene id: 645517:A6F65_RS11045
uniprot id: A0A1C7DB38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS09555
gene id: 645517:A6F65_RS09555
uniprot id: A0A1C7D9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

645517:A6F65 RS11135
gene id: 645517:A6F65_RS11135
uniprot id: A0A1C7DAM5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06025
gene id: 645517:A6F65_RS06025
uniprot id: A0A1C7D7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

645517:A6F65 RS05745
gene id: 645517:A6F65_RS05745
uniprot id: A0A1C7D7R2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

645517:A6F65 RS03190
gene id: 645517:A6F65_RS03190
uniprot id: A0A1C7D690
names: Subcellular Location Annotation
messages: Mitochondrion

645517:A6F65 RS02135
gene id: 645517:A6F65_RS02135
uniprot id: A0A1C7D5M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

645517:A6F65 RS12155
gene id: 645517:A6F65_RS12155
uniprot id: A0A1C7DBR0
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

645517:A6F65 RS03640
gene id: 645517:A6F65_RS03640
uniprot id: A0A1C7D6W6
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS03980
gene id: 645517:A6F65_RS03980
uniprot id: A0A1C7D6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

645517:A6F65 RS09005
gene id: 645517:A6F65_RS09005
uniprot id: A0A1C7D9M2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

645517:A6F65 RS09245
gene id: 645517:A6F65_RS09245
uniprot id: A0A1C7D9M8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

645517:A6F65 RS06615
gene id: 645517:A6F65_RS06615
uniprot id: A0A1C7D883
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

645517:A6F65 RS09675
gene id: 645517:A6F65_RS09675
uniprot id: A0A1C7D9T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

645517:A6F65 RS01470
gene id: 645517:A6F65_RS01470
uniprot id: A0A1C7D587
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

645517:A6F65 RS11285
gene id: 645517:A6F65_RS11285
uniprot id: A0A1C7DAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

645517:A6F65 RS08825
gene id: 645517:A6F65_RS08825
uniprot id: A0A1C7D9F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS10175
gene id: 645517:A6F65_RS10175
uniprot id: A0A1C7DA43
names: Similarity
messages: Belongs to the SELO family.

645517:A6F65 RS00600
gene id: 645517:A6F65_RS00600
uniprot id: A0A1C7D4S4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS06555
gene id: 645517:A6F65_RS06555
uniprot id: A0A1C7D8M5
names: Similarity
messages: Belongs to the peptidase S9A family.

645517:A6F65 RS11120
gene id: 645517:A6F65_RS11120
uniprot id: A0A1C7DAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

645517:A6F65 RS00425
gene id: 645517:A6F65_RS00425
uniprot id: A0A1C7D4N0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

645517:A6F65 RS09640
gene id: 645517:A6F65_RS09640
uniprot id: A0A1C7DA51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

645517:A6F65 RS07880
gene id: 645517:A6F65_RS07880
uniprot id: A0A1C7D8U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645517:A6F65 RS08100
gene id: 645517:A6F65_RS08100
uniprot id: A0A1C7D9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

645517:A6F65 RS03675
gene id: 645517:A6F65_RS03675
uniprot id: A0A1C7D6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

645517:A6F65 RS08140
gene id: 645517:A6F65_RS08140
uniprot id: A0A1C7D8Y9
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

645517:A6F65 RS05495
gene id: 645517:A6F65_RS05495
uniprot id: A0A1C7D7K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

645517:A6F65 RS02260
gene id: 645517:A6F65_RS02260
uniprot id: A0A1C7D601
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

645517:A6F65 RS04375
gene id: 645517:A6F65_RS04375
uniprot id: A0A1C7D6V3
names: Similarity
messages: Belongs to the DEAD box helicase family.

645517:A6F65 RS11565
gene id: 645517:A6F65_RS11565
uniprot id: A0A1C7DB06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06445
gene id: 645517:A6F65_RS06445
uniprot id: A0A1C7D8H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

645517:A6F65 RS09605
gene id: 645517:A6F65_RS09605
uniprot id: A0A1C7D9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

645517:A6F65 RS07000
gene id: 645517:A6F65_RS07000
uniprot id: A0A1C7D8P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

645517:A6F65 RS08840
gene id: 645517:A6F65_RS08840
uniprot id: A0A1C7D9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS06435
gene id: 645517:A6F65_RS06435
uniprot id: A0A1C7D808
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

645517:A6F65 RS07275
gene id: 645517:A6F65_RS07275
uniprot id: A0A1C7D8I0
names: Similarity
messages: Belongs to the peptidase S66 family.

645517:A6F65 RS12230
gene id: 645517:A6F65_RS12230
uniprot id: A0A1C7DBA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS02505
gene id: 645517:A6F65_RS02505
uniprot id: A0A1C7D5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

645517:A6F65 RS06780
gene id: 645517:A6F65_RS06780
uniprot id: A0A1C7D8A3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

645517:A6F65 RS01725
gene id: 645517:A6F65_RS01725
uniprot id: A0A1C7D5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

645517:A6F65 RS03055
gene id: 645517:A6F65_RS03055
uniprot id: A0A1C7D6F6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

645517:A6F65 RS11245
gene id: 645517:A6F65_RS11245
uniprot id: A0A1C7DB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

645517:A6F65 RS05700
gene id: 645517:A6F65_RS05700
uniprot id: A0A1C7D7P3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

645517:A6F65 RS02750
gene id: 645517:A6F65_RS02750
uniprot id: A0A1C7D6D0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645517:A6F65 RS06805
gene id: 645517:A6F65_RS06805
uniprot id: A0A1C7D8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

645517:A6F65 RS12260
gene id: 645517:A6F65_RS12260
uniprot id: A0A1C7DB91
names: Subcellular Location Annotation
messages: Cytoplasm

645517:A6F65 RS04390
gene id: 645517:A6F65_RS04390
uniprot id: A0A1C7D773
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

645517:A6F65 RS08105
gene id: 645517:A6F65_RS08105
uniprot id: A0A1C7D9G2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

645517:A6F65 RS08270
gene id: 645517:A6F65_RS08270
uniprot id: A0A1C7D913
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

645517:A6F65 RS11085
gene id: 645517:A6F65_RS11085
uniprot id: A0A1C7DAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

645517:A6F65 RS08850
gene id: 645517:A6F65_RS08850
uniprot id: A0A1C7D9V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS07925
gene id: 645517:A6F65_RS07925
uniprot id: A0A1C7D8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS09375
gene id: 645517:A6F65_RS09375
uniprot id: A0A1C7D9N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS00430
gene id: 645517:A6F65_RS00430
uniprot id: A0A1C7D4M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

645517:A6F65 RS11900
gene id: 645517:A6F65_RS11900
uniprot id: A0A1C7DB21
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

645517:A6F65 RS11125
gene id: 645517:A6F65_RS11125
uniprot id: A0A1C7DAU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS08470
gene id: 645517:A6F65_RS08470
uniprot id: A0A1C7D954
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08685
gene id: 645517:A6F65_RS08685
uniprot id: A0A1C7D998
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS01000
gene id: 645517:A6F65_RS01000
uniprot id: A0A1C7D4Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

645517:A6F65 RS04920
gene id: 645517:A6F65_RS04920
uniprot id: A0A1C7D7H7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS10435
gene id: 645517:A6F65_RS10435
uniprot id: A0A1C7DAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

645517:A6F65 RS06940
gene id: 645517:A6F65_RS06940
uniprot id: A0A1C7D8B2
names: Similarity
messages: Belongs to the DEAD box helicase family.

645517:A6F65 RS07805
gene id: 645517:A6F65_RS07805
uniprot id: A0A1C7D8W9
names: Similarity
messages: Belongs to the RecJ family.

645517:A6F65 RS12505
gene id: 645517:A6F65_RS12505
uniprot id: A0A1C7DBI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

645517:A6F65 RS00340
gene id: 645517:A6F65_RS00340
uniprot id: A0A1C7D4L1
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS06120
gene id: 645517:A6F65_RS06120
uniprot id: A0A1C7D7V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

645517:A6F65 RS11990
gene id: 645517:A6F65_RS11990
uniprot id: A0A1C7DBC3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS05720
gene id: 645517:A6F65_RS05720
uniprot id: A0A1C7D7Z0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

645517:A6F65 RS09800
gene id: 645517:A6F65_RS09800
uniprot id: A0A1C7DA79
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS07250
gene id: 645517:A6F65_RS07250
uniprot id: A0A1C7D8H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

645517:A6F65 RS02930
gene id: 645517:A6F65_RS02930
uniprot id: A0A1C7D5Z8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS09660
gene id: 645517:A6F65_RS09660
uniprot id: A0A1C7D9U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

645517:A6F65 RS06365
gene id: 645517:A6F65_RS06365
uniprot id: A0A1C7D8I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS08730
gene id: 645517:A6F65_RS08730
uniprot id: A0A1C7D9A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS01595
gene id: 645517:A6F65_RS01595
uniprot id: A0A1C7D5B3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

645517:A6F65 RS03165
gene id: 645517:A6F65_RS03165
uniprot id: A0A1C7D681
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

645517:A6F65 RS08680
gene id: 645517:A6F65_RS08680
uniprot id: A0A1C7D995
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

645517:A6F65 RS12400
gene id: 645517:A6F65_RS12400
uniprot id: A0A1C7DBG6
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS05825
gene id: 645517:A6F65_RS05825
uniprot id: A0A1C7D877
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

645517:A6F65 RS08365
gene id: 645517:A6F65_RS08365
uniprot id: A0A1C7D989
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

645517:A6F65 RS06515
gene id: 645517:A6F65_RS06515
uniprot id: A0A1C7D867
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

645517:A6F65 RS02775
gene id: 645517:A6F65_RS02775
uniprot id: A0A1C7D5W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS05345
gene id: 645517:A6F65_RS05345
uniprot id: A0A1C7D7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

645517:A6F65 RS06685
gene id: 645517:A6F65_RS06685
uniprot id: A0A1C7D866
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

645517:A6F65 RS06395
gene id: 645517:A6F65_RS06395
uniprot id: A0A1C7D8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

645517:A6F65 RS08735
gene id: 645517:A6F65_RS08735
uniprot id: A0A1C7D9B1
names: Similarity
messages: Belongs to the TrpC family.

645517:A6F65 RS01680
gene id: 645517:A6F65_RS01680
uniprot id: A0A1C7D5A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

645517:A6F65 RS03795
gene id: 645517:A6F65_RS03795
uniprot id: A0A1C7D6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS06085
gene id: 645517:A6F65_RS06085
uniprot id: A0A1C7D7X9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

645517:A6F65 RS05150
gene id: 645517:A6F65_RS05150
uniprot id: A0A1C7D7E4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

645517:A6F65 RS01165
gene id: 645517:A6F65_RS01165
uniprot id: A0A1C7D5I5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS11585
gene id: 645517:A6F65_RS11585
uniprot id: A0A1C7DAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS01625
gene id: 645517:A6F65_RS01625
uniprot id: A0A1C7D5B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

645517:A6F65 RS03925
gene id: 645517:A6F65_RS03925
uniprot id: A0A1C7D6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

645517:A6F65 RS11995
gene id: 645517:A6F65_RS11995
uniprot id: A0A1C7DB86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

645517:A6F65 RS08765
gene id: 645517:A6F65_RS08765
uniprot id: A0A1C7D9B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS10320
gene id: 645517:A6F65_RS10320
uniprot id: A0A1C7DAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

645517:A6F65 RS09655
gene id: 645517:A6F65_RS09655
uniprot id: A0A1C7DA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

645517:A6F65 RS12335
gene id: 645517:A6F65_RS12335
uniprot id: A0A1C7DBB6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

645517:A6F65 RS11095
gene id: 645517:A6F65_RS11095
uniprot id: A0A1C7DB48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

645517:A6F65 RS01845
gene id: 645517:A6F65_RS01845
uniprot id: A0A1C7D5G5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS01215
gene id: 645517:A6F65_RS01215
uniprot id: A0A1C7D5J5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

645517:A6F65 RS09865
gene id: 645517:A6F65_RS09865
uniprot id: A0A1C7DA35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645517:A6F65 RS12560
gene id: 645517:A6F65_RS12560
uniprot id: A0A1C7DBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

645517:A6F65 RS06205
gene id: 645517:A6F65_RS06205
uniprot id: A0A1C7D890
names: Similarity
messages: Belongs to the peptidase M16 family.

645517:A6F65 RS05385
gene id: 645517:A6F65_RS05385
uniprot id: A0A1C7D7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645517:A6F65 RS05280
gene id: 645517:A6F65_RS05280
uniprot id: A0A1C7D7D4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

645517:A6F65 RS01065
gene id: 645517:A6F65_RS01065
uniprot id: A0A1C7D5G9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07010
gene id: 645517:A6F65_RS07010
uniprot id: A0A1C7D8D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

645517:A6F65 RS10125
gene id: 645517:A6F65_RS10125
uniprot id: A0A1C7DA33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

645517:A6F65 RS10900
gene id: 645517:A6F65_RS10900
uniprot id: A0A1C7DB33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

645517:A6F65 RS00500
gene id: 645517:A6F65_RS00500
uniprot id: A0A1C7D4Q0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

645517:A6F65 RS08745
gene id: 645517:A6F65_RS08745
uniprot id: A0A1C7D9M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

645517:A6F65 RS12625
gene id: 645517:A6F65_RS12625
uniprot id: A0A1C7DC02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

645517:A6F65 RS12065
gene id: 645517:A6F65_RS12065
uniprot id: A0A1C7DBH0
names: Similarity
messages: Belongs to the YkuD family.

645517:A6F65 RS01640
gene id: 645517:A6F65_RS01640
uniprot id: A0A1C7D5C4
names: Similarity
messages: Belongs to the peptidase M1 family.

645517:A6F65 RS10520
gene id: 645517:A6F65_RS10520
uniprot id: A0A1C7DAE1
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS01540
gene id: 645517:A6F65_RS01540
uniprot id: A0A1C7D5B2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

645517:A6F65 RS04795
gene id: 645517:A6F65_RS04795
uniprot id: A0A1C7D722
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

645517:A6F65 RS11490
gene id: 645517:A6F65_RS11490
uniprot id: A0A1C7DAU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

645517:A6F65 RS05470
gene id: 645517:A6F65_RS05470
uniprot id: A0A1C7D807
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

645517:A6F65 RS03650
gene id: 645517:A6F65_RS03650
uniprot id: A0A1C7D6Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

645517:A6F65 RS02255
gene id: 645517:A6F65_RS02255
uniprot id: A0A1C7D625
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

645517:A6F65 RS00125
gene id: 645517:A6F65_RS00125
uniprot id: A0A1C7D4H0
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00765
gene id: 645517:A6F65_RS00765
uniprot id: A0A1C7D548
names: Similarity
messages: Belongs to the band 7/mec-2 family.

645517:A6F65 RS10875
gene id: 645517:A6F65_RS10875
uniprot id: A0A1C7DAM1
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

645517:A6F65 RS03800
gene id: 645517:A6F65_RS03800
uniprot id: A0A1C7D718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

645517:A6F65 RS09505
gene id: 645517:A6F65_RS09505
uniprot id: A0A1C7D9Q6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

645517:A6F65 RS07420
gene id: 645517:A6F65_RS07420
uniprot id: A0A1C7D8X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

645517:A6F65 RS01090
gene id: 645517:A6F65_RS01090
uniprot id: A0A1C7D505
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS07675
gene id: 645517:A6F65_RS07675
uniprot id: A0A1C7D8Q5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS05865
gene id: 645517:A6F65_RS05865
uniprot id: A0A1C7D852
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

645517:A6F65 RS04600
gene id: 645517:A6F65_RS04600
uniprot id: A0A1C7D6Y7
names: Similarity
messages: Belongs to the MipA/OmpV family.

645517:A6F65 RS07310
gene id: 645517:A6F65_RS07310
uniprot id: A0A1C7D8Z7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

645517:A6F65 RS10430
gene id: 645517:A6F65_RS10430
uniprot id: A0A1C7DA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

645517:A6F65 RS08285
gene id: 645517:A6F65_RS08285
uniprot id: A0A1C7D922
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

645517:A6F65 RS06990
gene id: 645517:A6F65_RS06990
uniprot id: A0A1C7D8C4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

645517:A6F65 RS02625
gene id: 645517:A6F65_RS02625
uniprot id: A0A1C7D5W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

645517:A6F65 RS01465
gene id: 645517:A6F65_RS01465
uniprot id: A0A1C7D584
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

645517:A6F65 RS05965
gene id: 645517:A6F65_RS05965
uniprot id: A0A1C7D834
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

645517:A6F65 RS05620
gene id: 645517:A6F65_RS05620
uniprot id: A0A1C7D7X4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

645517:A6F65 RS06840
gene id: 645517:A6F65_RS06840
uniprot id: A0A1C7D891
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

645517:A6F65 RS02150
gene id: 645517:A6F65_RS02150
uniprot id: A0A1C7D5L6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

645517:A6F65 RS08755
gene id: 645517:A6F65_RS08755
uniprot id: A0A1C7D9D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

645517:A6F65 RS03805
gene id: 645517:A6F65_RS03805
uniprot id: A0A1C7D6K9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

645517:A6F65 RS11715
gene id: 645517:A6F65_RS11715
uniprot id: A0A1C7DB37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

645517:A6F65 RS12515
gene id: 645517:A6F65_RS12515
uniprot id: A0A1C7DBE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

645517:A6F65 RS04865
gene id: 645517:A6F65_RS04865
uniprot id: A0A1C7D7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

645517:A6F65 RS08615
gene id: 645517:A6F65_RS08615
uniprot id: A0A1C7D977
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

645517:A6F65 RS06720
gene id: 645517:A6F65_RS06720
uniprot id: A0A1C7D860
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

645517:A6F65 RS02355
gene id: 645517:A6F65_RS02355
uniprot id: A0A1C7D645
names: Similarity
messages: Belongs to the HesB/IscA family.

645517:A6F65 RS05935
gene id: 645517:A6F65_RS05935
uniprot id: A0A1C7D7Q5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

645517:A6F65 RS08830
gene id: 645517:A6F65_RS08830
uniprot id: A0A1C7D9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

645517:A6F65 RS09890
gene id: 645517:A6F65_RS09890
uniprot id: A0A1C7D9X3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

645517:A6F65 RS08915
gene id: 645517:A6F65_RS08915
uniprot id: A0A1C7D9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS10335
gene id: 645517:A6F65_RS10335
uniprot id: A0A1C7DAB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

645517:A6F65 RS00490
gene id: 645517:A6F65_RS00490
uniprot id: A0A1C7D4N7
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

645517:A6F65 RS00625
gene id: 645517:A6F65_RS00625
uniprot id: A0A1C7D4R8
names: Similarity
messages: Belongs to the Gfa family.

645517:A6F65 RS07900
gene id: 645517:A6F65_RS07900
uniprot id: A0A1C7D9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

645517:A6F65 RS06500
gene id: 645517:A6F65_RS06500
uniprot id: A0A1C7D8F1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

645517:A6F65 RS12185
gene id: 645517:A6F65_RS12185
uniprot id: A0A1C7DBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS07470
gene id: 645517:A6F65_RS07470
uniprot id: A0A1C7D8Y5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

645517:A6F65 RS02535
gene id: 645517:A6F65_RS02535
uniprot id: A0A1C7D5V4
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

645517:A6F65 RS07640
gene id: 645517:A6F65_RS07640
uniprot id: A0A1C7D8Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS00760
gene id: 645517:A6F65_RS00760
uniprot id: A0A1C7D579
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS06765
gene id: 645517:A6F65_RS06765
uniprot id: A0A1C7D8B3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

645517:A6F65 RS08410
gene id: 645517:A6F65_RS08410
uniprot id: A0A1C7D948
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

645517:A6F65 RS09200
gene id: 645517:A6F65_RS09200
uniprot id: A0A1C7D9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

645517:A6F65 RS10265
gene id: 645517:A6F65_RS10265
uniprot id: A0A1C7DA93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS01035
gene id: 645517:A6F65_RS01035
uniprot id: A0A1C7D4Y7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08700
gene id: 645517:A6F65_RS08700
uniprot id: A0A1C7D9S9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

645517:A6F65 RS10025
gene id: 645517:A6F65_RS10025
uniprot id: A0A1C7DA42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

645517:A6F65 RS06270
gene id: 645517:A6F65_RS06270
uniprot id: A0A1C7D7X8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

645517:A6F65 RS05215
gene id: 645517:A6F65_RS05215
uniprot id: A0A1C7D7S7
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS07660
gene id: 645517:A6F65_RS07660
uniprot id: A0A1C7D8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

645517:A6F65 RS08975
gene id: 645517:A6F65_RS08975
uniprot id: A0A1C7D9X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

645517:A6F65 RS05305
gene id: 645517:A6F65_RS05305
uniprot id: A0A1C7D7D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

645517:A6F65 RS07745
gene id: 645517:A6F65_RS07745
uniprot id: A0A1C7D8R7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

645517:A6F65 RS05325
gene id: 645517:A6F65_RS05325
uniprot id: A0A1C7D7X0
names: Similarity
messages: Belongs to the asparaginase 1 family.

645517:A6F65 RS02615
gene id: 645517:A6F65_RS02615
uniprot id: A0A1C7D6B9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

645517:A6F65 RS08815
gene id: 645517:A6F65_RS08815
uniprot id: A0A1C7D9C4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS01520
gene id: 645517:A6F65_RS01520
uniprot id: A0A1C7D598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

645517:A6F65 RS02825
gene id: 645517:A6F65_RS02825
uniprot id: A0A1C7D615
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07225
gene id: 645517:A6F65_RS07225
uniprot id: A0A1C7D8K7
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

645517:A6F65 RS05955
gene id: 645517:A6F65_RS05955
uniprot id: A0A1C7D7R0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

645517:A6F65 RS09105
gene id: 645517:A6F65_RS09105
uniprot id: A0A1C7D9P0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

645517:A6F65 RS00120
gene id: 645517:A6F65_RS00120
uniprot id: A0A1C7D4S2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

645517:A6F65 RS10710
gene id: 645517:A6F65_RS10710
uniprot id: A0A1C7DAI4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

645517:A6F65 RS08360
gene id: 645517:A6F65_RS08360
uniprot id: A0A1C7D938
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

645517:A6F65 RS07245
gene id: 645517:A6F65_RS07245
uniprot id: A0A1C7D8J8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

645517:A6F65 RS09775
gene id: 645517:A6F65_RS09775
uniprot id: A0A1C7DA19
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645517:A6F65 RS07240
gene id: 645517:A6F65_RS07240
uniprot id: A0A1C7D8K8
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

645517:A6F65 RS09750
gene id: 645517:A6F65_RS09750
uniprot id: A0A1C7DAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

645517:A6F65 RS01740
gene id: 645517:A6F65_RS01740
uniprot id: A0A1C7D5E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

645517:A6F65 RS11355
gene id: 645517:A6F65_RS11355
uniprot id: A0A1C7DBD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

645517:A6F65 RS01495
gene id: 645517:A6F65_RS01495
uniprot id: A0A1C7D594
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

645517:A6F65 RS06390
gene id: 645517:A6F65_RS06390
uniprot id: A0A1C7D800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

645517:A6F65 RS05315
gene id: 645517:A6F65_RS05315
uniprot id: A0A1C7D7U6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645517:A6F65 RS11010
gene id: 645517:A6F65_RS11010
uniprot id: A0A1C7DAP4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645517:A6F65 RS10255
gene id: 645517:A6F65_RS10255
uniprot id: A0A1C7DAG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645517:A6F65 RS06735
gene id: 645517:A6F65_RS06735
uniprot id: A0A1C7D874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

645517:A6F65 RS10145
gene id: 645517:A6F65_RS10145
uniprot id: A0A1C7DA44
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

645517:A6F65 RS01450
gene id: 645517:A6F65_RS01450
uniprot id: A0A1C7D5L7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645517:A6F65 RS03135
gene id: 645517:A6F65_RS03135
uniprot id: A0A1C7D676
names: Similarity
messages: Belongs to the peptidase M24B family.

645517:A6F65 RS02820
gene id: 645517:A6F65_RS02820
uniprot id: A0A1C7D5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS10205
gene id: 645517:A6F65_RS10205
uniprot id: A0A1C7DAG2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07975
gene id: 645517:A6F65_RS07975
uniprot id: A0A1C7D8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS10705
gene id: 645517:A6F65_RS10705
uniprot id: A0A1C7DAZ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

645517:A6F65 RS00975
gene id: 645517:A6F65_RS00975
uniprot id: A0A1C7D4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

645517:A6F65 RS06310
gene id: 645517:A6F65_RS06310
uniprot id: A0A1C7D8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

645517:A6F65 RS11890
gene id: 645517:A6F65_RS11890
uniprot id: A0A1C7DB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

645517:A6F65 RS06425
gene id: 645517:A6F65_RS06425
uniprot id: A0A1C7D848
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

645517:A6F65 RS11210
gene id: 645517:A6F65_RS11210
uniprot id: A0A1C7DAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

645517:A6F65 RS08370
gene id: 645517:A6F65_RS08370
uniprot id: A0A1C7D933
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

645517:A6F65 RS11060
gene id: 645517:A6F65_RS11060
uniprot id: A0A1C7DAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

645517:A6F65 RS02980
gene id: 645517:A6F65_RS02980
uniprot id: A0A1C7D646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

645517:A6F65 RS12615
gene id: 645517:A6F65_RS12615
uniprot id: A0A1C7DBG9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

645517:A6F65 RS09255
gene id: 645517:A6F65_RS09255
uniprot id: A0A1C7D9K9
names: Similarity
messages: Belongs to the thioredoxin family.

645517:A6F65 RS05035
gene id: 645517:A6F65_RS05035
uniprot id: A0A1C7D783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

645517:A6F65 RS09870
gene id: 645517:A6F65_RS09870
uniprot id: A0A1C7D9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

645517:A6F65 RS08335
gene id: 645517:A6F65_RS08335
uniprot id: A0A1C7D930
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

645517:A6F65 RS06550
gene id: 645517:A6F65_RS06550
uniprot id: A0A1C7D8F9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

645517:A6F65 RS08210
gene id: 645517:A6F65_RS08210
uniprot id: A0A1C7D956
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

645517:A6F65 RS08175
gene id: 645517:A6F65_RS08175
uniprot id: A0A1C7D942
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645517:A6F65 RS09860
gene id: 645517:A6F65_RS09860
uniprot id: A0A1C7DA04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645517:A6F65 RS12535
gene id: 645517:A6F65_RS12535
uniprot id: A0A1C7DC28
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS01560
gene id: 645517:A6F65_RS01560
uniprot id: A0A1C7D5R4
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

645517:A6F65 RS11275
gene id: 645517:A6F65_RS11275
uniprot id: A0A1C7DAY1
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08185
gene id: 645517:A6F65_RS08185
uniprot id: A0A1C7D902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

645517:A6F65 RS02780
gene id: 645517:A6F65_RS02780
uniprot id: A0A1C7D606
names: Similarity
messages: Belongs to the UDPGP type 2 family.

645517:A6F65 RS09145
gene id: 645517:A6F65_RS09145
uniprot id: A0A1C7D9Q2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

645517:A6F65 RS02955
gene id: 645517:A6F65_RS02955
uniprot id: A0A1C7D6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

645517:A6F65 RS00145
gene id: 645517:A6F65_RS00145
uniprot id: A0A1C7D4H5
names: Similarity
messages: Belongs to the YciI family.

645517:A6F65 RS06465
gene id: 645517:A6F65_RS06465
uniprot id: A0A1C7D854
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

645517:A6F65 RS07170
gene id: 645517:A6F65_RS07170
uniprot id: A0A1C7D8F8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

645517:A6F65 RS04515
gene id: 645517:A6F65_RS04515
uniprot id: A0A1C7D706
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

645517:A6F65 RS12900
gene id: 645517:A6F65_RS12900
uniprot id: A0A1C7D8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

645517:A6F65 RS03905
gene id: 645517:A6F65_RS03905
uniprot id: A0A1C7D737
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08010
gene id: 645517:A6F65_RS08010
uniprot id: A0A1C7D909
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06795
gene id: 645517:A6F65_RS06795
uniprot id: A0A1C7D8P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

645517:A6F65 RS09620
gene id: 645517:A6F65_RS09620
uniprot id: A0A1C7D9S5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

645517:A6F65 RS04010
gene id: 645517:A6F65_RS04010
uniprot id: A0A1C7D761
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

645517:A6F65 RS04905
gene id: 645517:A6F65_RS04905
uniprot id: A0A1C7D762
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645517:A6F65 RS08155
gene id: 645517:A6F65_RS08155
uniprot id: A0A1C7D9G7
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS01755
gene id: 645517:A6F65_RS01755
uniprot id: A0A1C7D5S5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

645517:A6F65 RS06410
gene id: 645517:A6F65_RS06410
uniprot id: A0A1C7D813
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

645517:A6F65 RS02330
gene id: 645517:A6F65_RS02330
uniprot id: A0A1C7D5N1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

645517:A6F65 RS04195
gene id: 645517:A6F65_RS04195
uniprot id: A0A1C7D6S6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

645517:A6F65 RS01425
gene id: 645517:A6F65_RS01425
uniprot id: A0A1C7D562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

645517:A6F65 RS05830
gene id: 645517:A6F65_RS05830
uniprot id: A0A1C7D7N9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

645517:A6F65 RS09140
gene id: 645517:A6F65_RS09140
uniprot id: A0A1C7D9K8
names: Similarity
messages: Belongs to the virb1 family.

645517:A6F65 RS09570
gene id: 645517:A6F65_RS09570
uniprot id: A0A1C7D9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

645517:A6F65 RS04285
gene id: 645517:A6F65_RS04285
uniprot id: A0A1C7D6W0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

645517:A6F65 RS02410
gene id: 645517:A6F65_RS02410
uniprot id: A0A1C7D674
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

645517:A6F65 RS01870
gene id: 645517:A6F65_RS01870
uniprot id: A0A1C7D5G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

645517:A6F65 RS01205
gene id: 645517:A6F65_RS01205
uniprot id: A0A1C7D5H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

645517:A6F65 RS08910
gene id: 645517:A6F65_RS08910
uniprot id: A0A1C7D9H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS11115
gene id: 645517:A6F65_RS11115
uniprot id: A0A1C7DAS2
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS03265
gene id: 645517:A6F65_RS03265
uniprot id: A0A1C7D6A1
names: Similarity
messages: Belongs to the Nth/MutY family.

645517:A6F65 RS00785
gene id: 645517:A6F65_RS00785
uniprot id: A0A1C7D4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

645517:A6F65 RS02600
gene id: 645517:A6F65_RS02600
uniprot id: A0A1C7D5V9
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

645517:A6F65 RS10770
gene id: 645517:A6F65_RS10770
uniprot id: A0A1C7DAF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

645517:A6F65 RS09705
gene id: 645517:A6F65_RS09705
uniprot id: A0A1C7DA08
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

645517:A6F65 RS07980
gene id: 645517:A6F65_RS07980
uniprot id: A0A1C7D8V7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

645517:A6F65 RS00635
gene id: 645517:A6F65_RS00635
uniprot id: A0A1C7D4Q2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

645517:A6F65 RS10385
gene id: 645517:A6F65_RS10385
uniprot id: A0A1C7DAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

645517:A6F65 RS04955
gene id: 645517:A6F65_RS04955
uniprot id: A0A1C7D769
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

645517:A6F65 RS06005
gene id: 645517:A6F65_RS06005
uniprot id: A0A1C7D7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

645517:A6F65 RS06885
gene id: 645517:A6F65_RS06885
uniprot id: A0A1C7D8A2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645517:A6F65 RS02430
gene id: 645517:A6F65_RS02430
uniprot id: A0A1C7D5T0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

645517:A6F65 RS05130
gene id: 645517:A6F65_RS05130
uniprot id: A0A1C7D7S9
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

645517:A6F65 RS02595
gene id: 645517:A6F65_RS02595
uniprot id: A0A1C7D5W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

645517:A6F65 RS07765
gene id: 645517:A6F65_RS07765
uniprot id: A0A1C7D8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

645517:A6F65 RS04130
gene id: 645517:A6F65_RS04130
uniprot id: A0A1C7D6S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

645517:A6F65 RS10785
gene id: 645517:A6F65_RS10785
uniprot id: A0A1C7DAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

645517:A6F65 RS07040
gene id: 645517:A6F65_RS07040
uniprot id: A0A1C7D8D6
names: Similarity
messages: Belongs to the UPF0758 family.

645517:A6F65 RS05405
gene id: 645517:A6F65_RS05405
uniprot id: A0A1C7D7F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS00155
gene id: 645517:A6F65_RS00155
uniprot id: A0A1C7D4H9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

645517:A6F65 RS07560
gene id: 645517:A6F65_RS07560
uniprot id: A0A1C7D8M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS02140
gene id: 645517:A6F65_RS02140
uniprot id: A0A1C7D5N0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07855
gene id: 645517:A6F65_RS07855
uniprot id: A0A1C7D8Y2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

645517:A6F65 RS09615
gene id: 645517:A6F65_RS09615
uniprot id: A0A1C7D9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

645517:A6F65 RS04810
gene id: 645517:A6F65_RS04810
uniprot id: A0A1C7D742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

645517:A6F65 RS07615
gene id: 645517:A6F65_RS07615
uniprot id: A0A1C7D8P1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

645517:A6F65 RS12280
gene id: 645517:A6F65_RS12280
uniprot id: A0A1C7DBF3
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00005
gene id: 645517:A6F65_RS00005
uniprot id: A0A1C7D4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

645517:A6F65 RS05575
gene id: 645517:A6F65_RS05575
uniprot id: A0A1C7D828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

645517:A6F65 RS08445
gene id: 645517:A6F65_RS08445
uniprot id: A0A1C7D9M3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

645517:A6F65 RS05425
gene id: 645517:A6F65_RS05425
uniprot id: A0A1C7D7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

645517:A6F65 RS02205
gene id: 645517:A6F65_RS02205
uniprot id: A0A1C7D613
names: Similarity
messages: Belongs to the peptidase S9C family.

645517:A6F65 RS13225
gene id: 645517:A6F65_RS13225
uniprot id: A0A1C7D5L2
names: Subcellular Location Annotation
messages: Cytoplasm

645517:A6F65 RS09190
gene id: 645517:A6F65_RS09190
uniprot id: A0A1C7D9L8
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

645517:A6F65 RS01080
gene id: 645517:A6F65_RS01080
uniprot id: A0A1C7D4Z4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

645517:A6F65 RS01095
gene id: 645517:A6F65_RS01095
uniprot id: A0A1C7D524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

645517:A6F65 RS05275
gene id: 645517:A6F65_RS05275
uniprot id: A0A1C7D7V9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

645517:A6F65 RS11195
gene id: 645517:A6F65_RS11195
uniprot id: A0A1C7DB65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645517:A6F65 RS06605
gene id: 645517:A6F65_RS06605
uniprot id: A0A1C7D8N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

645517:A6F65 RS03000
gene id: 645517:A6F65_RS03000
uniprot id: A0A1C7D6H5
names: Similarity
messages: Belongs to the peptidase M13 family.

645517:A6F65 RS06480
gene id: 645517:A6F65_RS06480
uniprot id: A0A1C7D845
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

645517:A6F65 RS05420
gene id: 645517:A6F65_RS05420
uniprot id: A0A1C7D7S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

645517:A6F65 RS07150
gene id: 645517:A6F65_RS07150
uniprot id: A0A1C7D8X3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

645517:A6F65 RS05355
gene id: 645517:A6F65_RS05355
uniprot id: A0A1C7D7H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

645517:A6F65 RS08845
gene id: 645517:A6F65_RS08845
uniprot id: A0A1C7D9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS00245
gene id: 645517:A6F65_RS00245
uniprot id: A0A1C7D4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

645517:A6F65 RS04690
gene id: 645517:A6F65_RS04690
uniprot id: A0A1C7D7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

645517:A6F65 RS07415
gene id: 645517:A6F65_RS07415
uniprot id: A0A1C7D919
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

645517:A6F65 RS07400
gene id: 645517:A6F65_RS07400
uniprot id: A0A1C7D8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

645517:A6F65 RS07690
gene id: 645517:A6F65_RS07690
uniprot id: A0A1C7D982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

645517:A6F65 RS09715
gene id: 645517:A6F65_RS09715
uniprot id: A0A1C7DA09
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

645517:A6F65 RS00555
gene id: 645517:A6F65_RS00555
uniprot id: A0A1C7D4Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645517:A6F65 RS04675
gene id: 645517:A6F65_RS04675
uniprot id: A0A1C7D713
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

645517:A6F65 RS12165
gene id: 645517:A6F65_RS12165
uniprot id: A0A1C7DBV6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

645517:A6F65 RS07015
gene id: 645517:A6F65_RS07015
uniprot id: A0A1C7D8G4
names: Similarity
messages: Belongs to the TrpF family.

645517:A6F65 RS01825
gene id: 645517:A6F65_RS01825
uniprot id: A0A1C7D5F6
names: Similarity
messages: Belongs to the PhzF family.

645517:A6F65 RS11080
gene id: 645517:A6F65_RS11080
uniprot id: A0A1C7DAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

645517:A6F65 RS07825
gene id: 645517:A6F65_RS07825
uniprot id: A0A1C7D8S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

645517:A6F65 RS04235
gene id: 645517:A6F65_RS04235
uniprot id: A0A1C7D6U4
names: Similarity
messages: Belongs to the SCO1/2 family.

645517:A6F65 RS03785
gene id: 645517:A6F65_RS03785
uniprot id: A0A1C7D6J9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

645517:A6F65 RS01695
gene id: 645517:A6F65_RS01695
uniprot id: A0A1C7D5D7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

645517:A6F65 RS02155
gene id: 645517:A6F65_RS02155
uniprot id: A0A1C7D602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

645517:A6F65 RS09990
gene id: 645517:A6F65_RS09990
uniprot id: A0A1C7DA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

645517:A6F65 RS06485
gene id: 645517:A6F65_RS06485
uniprot id: A0A1C7D817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

645517:A6F65 RS07760
gene id: 645517:A6F65_RS07760
uniprot id: A0A1C7D8W4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

645517:A6F65 RS10445
gene id: 645517:A6F65_RS10445
uniprot id: A0A1C7DA83
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS07775
gene id: 645517:A6F65_RS07775
uniprot id: A0A1C7D8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS05565
gene id: 645517:A6F65_RS05565
uniprot id: A0A1C7D7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

645517:A6F65 RS05850
gene id: 645517:A6F65_RS05850
uniprot id: A0A1C7D7S4
names: Similarity
messages: Belongs to the peptidase C56 family.

645517:A6F65 RS08050
gene id: 645517:A6F65_RS08050
uniprot id: A0A1C7D9E8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

645517:A6F65 RS05050
gene id: 645517:A6F65_RS05050
uniprot id: A0A1C7D7C3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

645517:A6F65 RS07370
gene id: 645517:A6F65_RS07370
uniprot id: A0A1C7D8W7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS00885
gene id: 645517:A6F65_RS00885
uniprot id: A0A1C7D4V2
names: Similarity
messages: Belongs to the pyruvate kinase family.

645517:A6F65 RS09535
gene id: 645517:A6F65_RS09535
uniprot id: A0A1C7DA87
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

645517:A6F65 RS08770
gene id: 645517:A6F65_RS08770
uniprot id: A0A1C7D9G5
names: Similarity
messages: Belongs to the citrate synthase family.

645517:A6F65 RS12040
gene id: 645517:A6F65_RS12040
uniprot id: A0A1C7DBD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS05950
gene id: 645517:A6F65_RS05950
uniprot id: A0A1C7D7Q7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

645517:A6F65 RS10980
gene id: 645517:A6F65_RS10980
uniprot id: A0A1C7DAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

645517:A6F65 RS08480
gene id: 645517:A6F65_RS08480
uniprot id: A0A1C7D990
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS05395
gene id: 645517:A6F65_RS05395
uniprot id: A0A1C7D7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

645517:A6F65 RS02000
gene id: 645517:A6F65_RS02000
uniprot id: A0A1C7D5I8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

645517:A6F65 RS09765
gene id: 645517:A6F65_RS09765
uniprot id: A0A1C7DA20
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

645517:A6F65 RS12060
gene id: 645517:A6F65_RS12060
uniprot id: A0A1C7DBN9
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

645517:A6F65 RS09525
gene id: 645517:A6F65_RS09525
uniprot id: A0A1C7D9Q7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

645517:A6F65 RS04585
gene id: 645517:A6F65_RS04585
uniprot id: A0A1C7D7D6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

645517:A6F65 RS03560
gene id: 645517:A6F65_RS03560
uniprot id: A0A1C7D6G1
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS07425
gene id: 645517:A6F65_RS07425
uniprot id: A0A1C7D935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS12255
gene id: 645517:A6F65_RS12255
uniprot id: A0A1C7DBA3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

645517:A6F65 RS00615
gene id: 645517:A6F65_RS00615
uniprot id: A0A1C7D519
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

645517:A6F65 RS06235
gene id: 645517:A6F65_RS06235
uniprot id: A0A1C7D806
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

645517:A6F65 RS02085
gene id: 645517:A6F65_RS02085
uniprot id: A0A1C7D5L0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS07070
gene id: 645517:A6F65_RS07070
uniprot id: A0A1C7D8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

645517:A6F65 RS06140
gene id: 645517:A6F65_RS06140
uniprot id: A0A1C7D7V5
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

645517:A6F65 RS10115
gene id: 645517:A6F65_RS10115
uniprot id: A0A1C7DA62
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

645517:A6F65 RS04580
gene id: 645517:A6F65_RS04580
uniprot id: A0A1C7D6Y9
names: Similarity
messages: Belongs to the LOG family.

645517:A6F65 RS06175
gene id: 645517:A6F65_RS06175
uniprot id: A0A1C7D7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS00160
gene id: 645517:A6F65_RS00160
uniprot id: A0A1C7D4W3
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

645517:A6F65 RS01835
gene id: 645517:A6F65_RS01835
uniprot id: A0A1C7D5F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

645517:A6F65 RS10095
gene id: 645517:A6F65_RS10095
uniprot id: A0A1C7DA34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

645517:A6F65 RS10275
gene id: 645517:A6F65_RS10275
uniprot id: A0A1C7DA59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

645517:A6F65 RS00835
gene id: 645517:A6F65_RS00835
uniprot id: A0A1C7D4U1
names: Similarity
messages: Belongs to the ArsC family.

645517:A6F65 RS03940
gene id: 645517:A6F65_RS03940
uniprot id: A0A1C7D6N1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

645517:A6F65 RS11455
gene id: 645517:A6F65_RS11455
uniprot id: A0A1C7DBF0
names: Similarity
messages: Belongs to the peptidase M16 family.

645517:A6F65 RS07035
gene id: 645517:A6F65_RS07035
uniprot id: A0A1C7D8D4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

645517:A6F65 RS10370
gene id: 645517:A6F65_RS10370
uniprot id: A0A1C7DAD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

645517:A6F65 RS12200
gene id: 645517:A6F65_RS12200
uniprot id: A0A1C7DB81
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645517:A6F65 RS01510
gene id: 645517:A6F65_RS01510
uniprot id: A0A1C7D5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

645517:A6F65 RS11690
gene id: 645517:A6F65_RS11690
uniprot id: A0A1C7DAZ2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

645517:A6F65 RS11600
gene id: 645517:A6F65_RS11600
uniprot id: A0A1C7DB85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

645517:A6F65 RS08385
gene id: 645517:A6F65_RS08385
uniprot id: A0A1C7D940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

645517:A6F65 RS12325
gene id: 645517:A6F65_RS12325
uniprot id: A0A1C7DBG4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

645517:A6F65 RS11655
gene id: 645517:A6F65_RS11655
uniprot id: A0A1C7DB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

645517:A6F65 RS10475
gene id: 645517:A6F65_RS10475
uniprot id: A0A1C7DAF9
names: Similarity
messages: Belongs to the cytochrome P450 family.

645517:A6F65 RS00580
gene id: 645517:A6F65_RS00580
uniprot id: A0A1C7D4Q4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

645517:A6F65 RS05375
gene id: 645517:A6F65_RS05375
uniprot id: A0A1C7D7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

645517:A6F65 RS07965
gene id: 645517:A6F65_RS07965
uniprot id: A0A1C7D8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS08695
gene id: 645517:A6F65_RS08695
uniprot id: A0A1C7D9L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

645517:A6F65 RS12585
gene id: 645517:A6F65_RS12585
uniprot id: A0A1C7DC39
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

645517:A6F65 RS06535
gene id: 645517:A6F65_RS06535
uniprot id: A0A1C7D832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

645517:A6F65 RS01490
gene id: 645517:A6F65_RS01490
uniprot id: A0A1C7D595
names: Similarity
messages: Belongs to the FBPase class 2 family.

645517:A6F65 RS08645
gene id: 645517:A6F65_RS08645
uniprot id: A0A1C7D9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

645517:A6F65 RS02735
gene id: 645517:A6F65_RS02735
uniprot id: A0A1C7D5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

645517:A6F65 RS07985
gene id: 645517:A6F65_RS07985
uniprot id: A0A1C7D8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

645517:A6F65 RS10720
gene id: 645517:A6F65_RS10720
uniprot id: A0A1C7DAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

645517:A6F65 RS05685
gene id: 645517:A6F65_RS05685
uniprot id: A0A1C7D7P0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

645517:A6F65 RS05705
gene id: 645517:A6F65_RS05705
uniprot id: A0A1C7D7K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

645517:A6F65 RS07665
gene id: 645517:A6F65_RS07665
uniprot id: A0A1C7D8P8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

645517:A6F65 RS08330
gene id: 645517:A6F65_RS08330
uniprot id: A0A1C7D965
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

645517:A6F65 RS07645
gene id: 645517:A6F65_RS07645
uniprot id: A0A1C7D8T7
names: Similarity
messages: Belongs to the YkuD family.

645517:A6F65 RS11750
gene id: 645517:A6F65_RS11750
uniprot id: A0A1C7DBI3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

645517:A6F65 RS09415
gene id: 645517:A6F65_RS09415
uniprot id: A0A1C7D9T4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

645517:A6F65 RS04260
gene id: 645517:A6F65_RS04260
uniprot id: A0A1C7D757
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

645517:A6F65 RS06210
gene id: 645517:A6F65_RS06210
uniprot id: A0A1C7D8F4
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

645517:A6F65 RS10930
gene id: 645517:A6F65_RS10930
uniprot id: A0A1C7DAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

645517:A6F65 RS09015
gene id: 645517:A6F65_RS09015
uniprot id: A0A1C7D9G4
names: Similarity
messages: Belongs to the pirin family.

645517:A6F65 RS06520
gene id: 645517:A6F65_RS06520
uniprot id: A0A1C7D821
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645517:A6F65 RS11530
gene id: 645517:A6F65_RS11530
uniprot id: A0A1C7DB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

645517:A6F65 RS11650
gene id: 645517:A6F65_RS11650
uniprot id: A0A1C7DBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

645517:A6F65 RS11385
gene id: 645517:A6F65_RS11385
uniprot id: A0A1C7DAS6
names: Similarity
messages: Belongs to the bacterial secretin family.

645517:A6F65 RS05415
gene id: 645517:A6F65_RS05415
uniprot id: A0A1C7D7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

645517:A6F65 RS00030
gene id: 645517:A6F65_RS00030
uniprot id: A0A1C7D4C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

645517:A6F65 RS10755
gene id: 645517:A6F65_RS10755
uniprot id: A0A1C7DB04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

645517:A6F65 RS12315
gene id: 645517:A6F65_RS12315
uniprot id: A0A1C7DBM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645517:A6F65 RS01615
gene id: 645517:A6F65_RS01615
uniprot id: A0A1C7D5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

645517:A6F65 RS06280
gene id: 645517:A6F65_RS06280
uniprot id: A0A1C7D7X2
names: Similarity
messages: Belongs to the TlyA family.

645517:A6F65 RS10305
gene id: 645517:A6F65_RS10305
uniprot id: A0A1C7DAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

645517:A6F65 RS08565
gene id: 645517:A6F65_RS08565
uniprot id: A0A1C7D969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

645517:A6F65 RS08905
gene id: 645517:A6F65_RS08905
uniprot id: A0A1C7D9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS03435
gene id: 645517:A6F65_RS03435
uniprot id: A0A1C7D6D6
names: Similarity
messages: Belongs to the YggT family.

645517:A6F65 RS05580
gene id: 645517:A6F65_RS05580
uniprot id: A0A1C7D7I8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

645517:A6F65 RS07910
gene id: 645517:A6F65_RS07910
uniprot id: A0A1C7D8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

645517:A6F65 RS09580
gene id: 645517:A6F65_RS09580
uniprot id: A0A1C7DA98
names: Similarity
messages: Belongs to the TPP enzyme family.

645517:A6F65 RS01455
gene id: 645517:A6F65_RS01455
uniprot id: A0A1C7D5J1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645517:A6F65 RS11310
gene id: 645517:A6F65_RS11310
uniprot id: A0A1C7DAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

645517:A6F65 RS05770
gene id: 645517:A6F65_RS05770
uniprot id: A0A1C7D7Z8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

645517:A6F65 RS10065
gene id: 645517:A6F65_RS10065
uniprot id: A0A1C7DAK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

645517:A6F65 RS03530
gene id: 645517:A6F65_RS03530
uniprot id: A0A1C7D6F8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

645517:A6F65 RS08835
gene id: 645517:A6F65_RS08835
uniprot id: A0A1C7D9D3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

645517:A6F65 RS11030
gene id: 645517:A6F65_RS11030
uniprot id: A0A1C7DAQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

645517:A6F65 RS08315
gene id: 645517:A6F65_RS08315
uniprot id: A0A1C7D976
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS12360
gene id: 645517:A6F65_RS12360
uniprot id: A0A1C7DBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

645517:A6F65 RS10310
gene id: 645517:A6F65_RS10310
uniprot id: A0A1C7DAQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS09360
gene id: 645517:A6F65_RS09360
uniprot id: A0A1C7D9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

645517:A6F65 RS04380
gene id: 645517:A6F65_RS04380
uniprot id: A0A1C7D6W5
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS00480
gene id: 645517:A6F65_RS00480
uniprot id: A0A1C7D4N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

645517:A6F65 RS02030
gene id: 645517:A6F65_RS02030
uniprot id: A0A1C7D5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

645517:A6F65 RS09685
gene id: 645517:A6F65_RS09685
uniprot id: A0A1C7DAB8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS05835
gene id: 645517:A6F65_RS05835
uniprot id: A0A1C7D7S3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

645517:A6F65 RS02125
gene id: 645517:A6F65_RS02125
uniprot id: A0A1C7D5M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645517:A6F65 RS06020
gene id: 645517:A6F65_RS06020
uniprot id: A0A1C7D8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

645517:A6F65 RS00280
gene id: 645517:A6F65_RS00280
uniprot id: A0A1C7D4J8
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

645517:A6F65 RS09470
gene id: 645517:A6F65_RS09470
uniprot id: A0A1C7D9P8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

645517:A6F65 RS02310
gene id: 645517:A6F65_RS02310
uniprot id: A0A1C7D612
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

645517:A6F65 RS12330
gene id: 645517:A6F65_RS12330
uniprot id: A0A1C7DBF8
names: Subcellular Location Annotation
messages: Membrane

645517:A6F65 RS08860
gene id: 645517:A6F65_RS08860
uniprot id: A0A1C7D9D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

645517:A6F65 RS01225
gene id: 645517:A6F65_RS01225
uniprot id: A0A1C7D534
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

645517:A6F65 RS10250
gene id: 645517:A6F65_RS10250
uniprot id: A0A1C7DAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645517:A6F65 RS09755
gene id: 645517:A6F65_RS09755
uniprot id: A0A1C7D9Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

645517:A6F65 RS05135
gene id: 645517:A6F65_RS05135
uniprot id: A0A1C7D7A1
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

645517:A6F65 RS11105
gene id: 645517:A6F65_RS11105
uniprot id: A0A1C7DB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

645517:A6F65 RS00825
gene id: 645517:A6F65_RS00825
uniprot id: A0A1C7D4V7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

645517:A6F65 RS06470
gene id: 645517:A6F65_RS06470
uniprot id: A0A1C7D810
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

645517:A6F65 RS06415
gene id: 645517:A6F65_RS06415
uniprot id: A0A1C7D846
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

645517:A6F65 RS11520
gene id: 645517:A6F65_RS11520
uniprot id: A0A1C7DAZ6
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

645517:A6F65 RS01905
gene id: 645517:A6F65_RS01905
uniprot id: A0A1C7D5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

645517:A6F65 RS03200
gene id: 645517:A6F65_RS03200
uniprot id: A0A1C7D6J3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645517:A6F65 RS07080
gene id: 645517:A6F65_RS07080
uniprot id: A0A1C7D8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

645517:A6F65 RS03485
gene id: 645517:A6F65_RS03485
uniprot id: A0A1C7D6D4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

645517:A6F65 RS06160
gene id: 645517:A6F65_RS06160
uniprot id: A0A1C7D8E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.