645127:CKROP RS10945
gene id: 645127:CKROP_RS10945
uniprot id: C4LLK0
names: Similarity
messages: Belongs to the GSP E family.

645127:CKROP RS05060
gene id: 645127:CKROP_RS05060
uniprot id: C4LIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645127:CKROP RS08340
gene id: 645127:CKROP_RS08340
uniprot id: C4LKQ7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

645127:CKROP RS04320
gene id: 645127:CKROP_RS04320
uniprot id: C4LIH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

645127:CKROP RS01960
gene id: 645127:CKROP_RS01960
uniprot id: C4LH80
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

645127:CKROP RS03900
gene id: 645127:CKROP_RS03900
uniprot id: C4LI96
names: Similarity
messages: Belongs to the TrpC family.

645127:CKROP RS05630
gene id: 645127:CKROP_RS05630
uniprot id: C4LJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

645127:CKROP RS08960
gene id: 645127:CKROP_RS08960
uniprot id: C4LL32
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

645127:CKROP RS02675
gene id: 645127:CKROP_RS02675
uniprot id: C4LHL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

645127:CKROP RS00730
gene id: 645127:CKROP_RS00730
uniprot id: C4LG87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

645127:CKROP RS05815
gene id: 645127:CKROP_RS05815
uniprot id: C4LJB9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

645127:CKROP RS08920
gene id: 645127:CKROP_RS08920
uniprot id: C4LL24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

645127:CKROP RS04550
gene id: 645127:CKROP_RS04550
uniprot id: C4LIM3
names: Similarity
messages: Belongs to the UPF0098 family.

645127:CKROP RS08775
gene id: 645127:CKROP_RS08775
uniprot id: C4LKZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

645127:CKROP RS03575
gene id: 645127:CKROP_RS03575
uniprot id: C4LI31
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

645127:CKROP RS06715
gene id: 645127:CKROP_RS06715
uniprot id: C4LJU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

645127:CKROP RS03830
gene id: 645127:CKROP_RS03830
uniprot id: C4LI82
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

645127:CKROP RS03580
gene id: 645127:CKROP_RS03580
uniprot id: C4LI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

645127:CKROP RS02155
gene id: 645127:CKROP_RS02155
uniprot id: C4LHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

645127:CKROP RS08570
gene id: 645127:CKROP_RS08570
uniprot id: C4LKV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

645127:CKROP RS02425
gene id: 645127:CKROP_RS02425
uniprot id: C4LHG2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

645127:CKROP RS02585
gene id: 645127:CKROP_RS02585
uniprot id: C4LHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

645127:CKROP RS08805
gene id: 645127:CKROP_RS08805
uniprot id: C4LL01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

645127:CKROP RS01585
gene id: 645127:CKROP_RS01585
uniprot id: C4LH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

645127:CKROP RS01840
gene id: 645127:CKROP_RS01840
uniprot id: C4LH56
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

645127:CKROP RS03460
gene id: 645127:CKROP_RS03460
uniprot id: C4LI09
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

645127:CKROP RS06010
gene id: 645127:CKROP_RS06010
uniprot id: C4LJF8
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07185
gene id: 645127:CKROP_RS07185
uniprot id: C4LK27
names: Similarity
messages: Belongs to the peptidase S1 family.

645127:CKROP RS04635
gene id: 645127:CKROP_RS04635
uniprot id: C4LIP0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

645127:CKROP RS05495
gene id: 645127:CKROP_RS05495
uniprot id: C4LJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

645127:CKROP RS06125
gene id: 645127:CKROP_RS06125
uniprot id: C4LJH8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

645127:CKROP RS02645
gene id: 645127:CKROP_RS02645
uniprot id: C4LHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

645127:CKROP RS04495
gene id: 645127:CKROP_RS04495
uniprot id: C4LIL2
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

645127:CKROP RS05040
gene id: 645127:CKROP_RS05040
uniprot id: C4LIX0
names: Similarity
messages: Belongs to the FPG family.

645127:CKROP RS02110
gene id: 645127:CKROP_RS02110
uniprot id: C4LHA3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

645127:CKROP RS04240
gene id: 645127:CKROP_RS04240
uniprot id: C4LIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS04720
gene id: 645127:CKROP_RS04720
uniprot id: C4LIQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

645127:CKROP RS08980
gene id: 645127:CKROP_RS08980
uniprot id: C4LL36
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

645127:CKROP RS09145
gene id: 645127:CKROP_RS09145
uniprot id: C4LL70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645127:CKROP RS09200
gene id: 645127:CKROP_RS09200
uniprot id: C4LL83
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

645127:CKROP RS01350
gene id: 645127:CKROP_RS01350
uniprot id: C4LGV8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

645127:CKROP RS01805
gene id: 645127:CKROP_RS01805
uniprot id: C4LH48
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS05915
gene id: 645127:CKROP_RS05915
uniprot id: C4LJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

645127:CKROP RS03090
gene id: 645127:CKROP_RS03090
uniprot id: C4LHT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

645127:CKROP RS04770
gene id: 645127:CKROP_RS04770
uniprot id: C4LIR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS05960
gene id: 645127:CKROP_RS05960
uniprot id: C4LJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

645127:CKROP RS01915
gene id: 645127:CKROP_RS01915
uniprot id: C4LH71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

645127:CKROP RS03050
gene id: 645127:CKROP_RS03050
uniprot id: C4LHT1
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

645127:CKROP RS04120
gene id: 645127:CKROP_RS04120
uniprot id: C4LID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

645127:CKROP RS08440
gene id: 645127:CKROP_RS08440
uniprot id: C4LKS6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS02610
gene id: 645127:CKROP_RS02610
uniprot id: C4LHJ8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

645127:CKROP RS04780
gene id: 645127:CKROP_RS04780
uniprot id: C4LIR8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

645127:CKROP RS06270
gene id: 645127:CKROP_RS06270
uniprot id: C4LJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

645127:CKROP RS09050
gene id: 645127:CKROP_RS09050
uniprot id: C4LL50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

645127:CKROP RS10940
gene id: 645127:CKROP_RS10940
uniprot id: C4LLJ9
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS08770
gene id: 645127:CKROP_RS08770
uniprot id: C4LKZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

645127:CKROP RS01380
gene id: 645127:CKROP_RS01380
uniprot id: C4LGW4
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

645127:CKROP RS07020
gene id: 645127:CKROP_RS07020
uniprot id: C4LJZ7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

645127:CKROP RS04825
gene id: 645127:CKROP_RS04825
uniprot id: C4LIS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

645127:CKROP RS05210
gene id: 645127:CKROP_RS05210
uniprot id: C4LIZ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

645127:CKROP RS10245
gene id: 645127:CKROP_RS10245
uniprot id: C4LGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

645127:CKROP RS06100
gene id: 645127:CKROP_RS06100
uniprot id: C4LJH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS09060
gene id: 645127:CKROP_RS09060
uniprot id: C4LL52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

645127:CKROP RS01295
gene id: 645127:CKROP_RS01295
uniprot id: C4LGU7
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS08545
gene id: 645127:CKROP_RS08545
uniprot id: C4LKU7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

645127:CKROP RS04070
gene id: 645127:CKROP_RS04070
uniprot id: C4LIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

645127:CKROP RS08380
gene id: 645127:CKROP_RS08380
uniprot id: C4LKR4
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04620
gene id: 645127:CKROP_RS04620
uniprot id: C4LIN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

645127:CKROP RS08360
gene id: 645127:CKROP_RS08360
uniprot id: C4LKR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

645127:CKROP RS02125
gene id: 645127:CKROP_RS02125
uniprot id: C4LHA5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

645127:CKROP RS09415
gene id: 645127:CKROP_RS09415
uniprot id: C4LLB9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

645127:CKROP RS09425
gene id: 645127:CKROP_RS09425
uniprot id: C4LLC1
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

645127:CKROP RS02460
gene id: 645127:CKROP_RS02460
uniprot id: C4LHG8
names: Similarity
messages: Belongs to the peptidase C56 family.

645127:CKROP RS00805
gene id: 645127:CKROP_RS00805
uniprot id: C4LGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Membrane

645127:CKROP RS10895
gene id: 645127:CKROP_RS10895
uniprot id: C4LL69
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

645127:CKROP RS08030
gene id: 645127:CKROP_RS08030
uniprot id: C4LKJ5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS02075
gene id: 645127:CKROP_RS02075
uniprot id: C4LH98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS05195
gene id: 645127:CKROP_RS05195
uniprot id: C4LIZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS07155
gene id: 645127:CKROP_RS07155
uniprot id: C4LK22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

645127:CKROP RS01335
gene id: 645127:CKROP_RS01335
uniprot id: C4LGV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

645127:CKROP RS08520
gene id: 645127:CKROP_RS08520
uniprot id: C4LKU2
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

645127:CKROP RS01635
gene id: 645127:CKROP_RS01635
uniprot id: C4LH17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS06995
gene id: 645127:CKROP_RS06995
uniprot id: C4LJZ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

645127:CKROP RS04570
gene id: 645127:CKROP_RS04570
uniprot id: C4LIM7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

645127:CKROP RS05275
gene id: 645127:CKROP_RS05275
uniprot id: C4LJ12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS02700
gene id: 645127:CKROP_RS02700
uniprot id: C4LHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

645127:CKROP RS08765
gene id: 645127:CKROP_RS08765
uniprot id: C4LKZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

645127:CKROP RS08985
gene id: 645127:CKROP_RS08985
uniprot id: C4LL37
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

645127:CKROP RS04915
gene id: 645127:CKROP_RS04915
uniprot id: C4LIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

645127:CKROP RS01810
gene id: 645127:CKROP_RS01810
uniprot id: C4LH49
names: Similarity
messages: Belongs to the glutathione peroxidase family.

645127:CKROP RS05015
gene id: 645127:CKROP_RS05015
uniprot id: C4LIW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS05765
gene id: 645127:CKROP_RS05765
uniprot id: C4LJA9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

645127:CKROP RS05600
gene id: 645127:CKROP_RS05600
uniprot id: C4LJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

645127:CKROP RS00080
gene id: 645127:CKROP_RS00080
uniprot id: C4LGA8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

645127:CKROP RS02180
gene id: 645127:CKROP_RS02180
uniprot id: C4LHB6
names: Similarity
messages: Belongs to the citrate synthase family.

645127:CKROP RS07480
gene id: 645127:CKROP_RS07480
uniprot id: C4LK86
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

645127:CKROP RS00580
gene id: 645127:CKROP_RS00580
uniprot id: C4LG73
names: Similarity
messages: Belongs to the pyruvate kinase family.

645127:CKROP RS09610
gene id: 645127:CKROP_RS09610
uniprot id: C4LLF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

645127:CKROP RS10195
gene id: 645127:CKROP_RS10195
uniprot id: C4LGF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

645127:CKROP RS07355
gene id: 645127:CKROP_RS07355
uniprot id: C4LK58
names: Similarity
messages: Belongs to the DEAD box helicase family.

645127:CKROP RS03010
gene id: 645127:CKROP_RS03010
uniprot id: C4LHS3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645127:CKROP RS00145
gene id: 645127:CKROP_RS00145
uniprot id: C4LGD0
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

645127:CKROP RS02500
gene id: 645127:CKROP_RS02500
uniprot id: C4LHH6
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07575
gene id: 645127:CKROP_RS07575
uniprot id: C4LKA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

645127:CKROP RS03880
gene id: 645127:CKROP_RS03880
uniprot id: C4LI92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

645127:CKROP RS04270
gene id: 645127:CKROP_RS04270
uniprot id: C4LIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

645127:CKROP RS00510
gene id: 645127:CKROP_RS00510
uniprot id: C4LG59
names: Similarity
messages: Belongs to the universal stress protein A family.

645127:CKROP RS08885
gene id: 645127:CKROP_RS08885
uniprot id: C4LL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS02630
gene id: 645127:CKROP_RS02630
uniprot id: C4LHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

645127:CKROP RS04080
gene id: 645127:CKROP_RS04080
uniprot id: C4LID1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

645127:CKROP RS03485
gene id: 645127:CKROP_RS03485
uniprot id: C4LI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

645127:CKROP RS00555
gene id: 645127:CKROP_RS00555
uniprot id: C4LG68
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

645127:CKROP RS01645
gene id: 645127:CKROP_RS01645
uniprot id: C4LH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS08930
gene id: 645127:CKROP_RS08930
uniprot id: C4LL26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

645127:CKROP RS06315
gene id: 645127:CKROP_RS06315
uniprot id: C4LJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

645127:CKROP RS04035
gene id: 645127:CKROP_RS04035
uniprot id: C4LIC2
names: Similarity
messages: Belongs to the universal stress protein A family.

645127:CKROP RS02185
gene id: 645127:CKROP_RS02185
uniprot id: C4LHB7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

645127:CKROP RS02550
gene id: 645127:CKROP_RS02550
uniprot id: C4LHI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

645127:CKROP RS03570
gene id: 645127:CKROP_RS03570
uniprot id: C4LI30
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

645127:CKROP RS06840
gene id: 645127:CKROP_RS06840
uniprot id: C4LJW7
names: Similarity
messages: Belongs to the Dps family.

645127:CKROP RS04830
gene id: 645127:CKROP_RS04830
uniprot id: C4LIS8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

645127:CKROP RS06335
gene id: 645127:CKROP_RS06335
uniprot id: C4LJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

645127:CKROP RS00560
gene id: 645127:CKROP_RS00560
uniprot id: C4LG69
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

645127:CKROP RS09175
gene id: 645127:CKROP_RS09175
uniprot id: C4LL77
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

645127:CKROP RS05640
gene id: 645127:CKROP_RS05640
uniprot id: C4LJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

645127:CKROP RS02850
gene id: 645127:CKROP_RS02850
uniprot id: C4LHP2
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS00160
gene id: 645127:CKROP_RS00160
uniprot id: C4LGD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS05490
gene id: 645127:CKROP_RS05490
uniprot id: C4LJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS02340
gene id: 645127:CKROP_RS02340
uniprot id: C4LHE6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

645127:CKROP RS01815
gene id: 645127:CKROP_RS01815
uniprot id: C4LH50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645127:CKROP RS04795
gene id: 645127:CKROP_RS04795
uniprot id: C4LIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

645127:CKROP RS08760
gene id: 645127:CKROP_RS08760
uniprot id: C4LKZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

645127:CKROP RS00565
gene id: 645127:CKROP_RS00565
uniprot id: C4LG70
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS02385
gene id: 645127:CKROP_RS02385
uniprot id: C4LHF4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS09365
gene id: 645127:CKROP_RS09365
uniprot id: C4LLB1
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07000
gene id: 645127:CKROP_RS07000
uniprot id: C4LJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

645127:CKROP RS01720
gene id: 645127:CKROP_RS01720
uniprot id: C4LH33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645127:CKROP RS04840
gene id: 645127:CKROP_RS04840
uniprot id: C4LIT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

645127:CKROP RS10960
gene id: 645127:CKROP_RS10960
uniprot id: C4LLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS04005
gene id: 645127:CKROP_RS04005
uniprot id: C4LIB6
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS09595
gene id: 645127:CKROP_RS09595
uniprot id: C4LLF6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

645127:CKROP RS04020
gene id: 645127:CKROP_RS04020
uniprot id: C4LIB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

645127:CKROP RS04750
gene id: 645127:CKROP_RS04750
uniprot id: C4LIR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645127:CKROP RS08575
gene id: 645127:CKROP_RS08575
uniprot id: C4LKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

645127:CKROP RS05845
gene id: 645127:CKROP_RS05845
uniprot id: C4LJC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

645127:CKROP RS02865
gene id: 645127:CKROP_RS02865
uniprot id: C4LHP5
names: Similarity
messages: Belongs to the FBPase class 2 family.

645127:CKROP RS04690
gene id: 645127:CKROP_RS04690
uniprot id: C4LIQ0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

645127:CKROP RS08640
gene id: 645127:CKROP_RS08640
uniprot id: C4LKW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

645127:CKROP RS03535
gene id: 645127:CKROP_RS03535
uniprot id: C4LI23
names: Similarity
messages: Belongs to the peptidase C40 family.

645127:CKROP RS05340
gene id: 645127:CKROP_RS05340
uniprot id: C4LJ25
names: Subcellular Location Annotation
messages: Cytoplasm

645127:CKROP RS01385
gene id: 645127:CKROP_RS01385
uniprot id: C4LGW5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645127:CKROP RS09355
gene id: 645127:CKROP_RS09355
uniprot id: C4LLA9
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS08600
gene id: 645127:CKROP_RS08600
uniprot id: C4LKV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

645127:CKROP RS03800
gene id: 645127:CKROP_RS03800
uniprot id: C4LI75
names: Similarity
messages: Belongs to the HSP15 family.

645127:CKROP RS00855
gene id: 645127:CKROP_RS00855
uniprot id: C4LGK8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS00900
gene id: 645127:CKROP_RS00900
uniprot id: C4LGL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

645127:CKROP RS05565
gene id: 645127:CKROP_RS05565
uniprot id: C4LJ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

645127:CKROP RS01725
gene id: 645127:CKROP_RS01725
uniprot id: C4LH34
names: Similarity
messages: Belongs to the fructosamine kinase family.

645127:CKROP RS00670
gene id: 645127:CKROP_RS00670
uniprot id: C4LG76
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS05380
gene id: 645127:CKROP_RS05380
uniprot id: C4LJ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

645127:CKROP RS06140
gene id: 645127:CKROP_RS06140
uniprot id: C4LJI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

645127:CKROP RS07100
gene id: 645127:CKROP_RS07100
uniprot id: C4LK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS02800
gene id: 645127:CKROP_RS02800
uniprot id: C4LHN2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

645127:CKROP RS01255
gene id: 645127:CKROP_RS01255
uniprot id: C4LGT9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

645127:CKROP RS02830
gene id: 645127:CKROP_RS02830
uniprot id: C4LHN8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

645127:CKROP RS01820
gene id: 645127:CKROP_RS01820
uniprot id: C4LH51
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645127:CKROP RS03455
gene id: 645127:CKROP_RS03455
uniprot id: C4LI08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

645127:CKROP RS02370
gene id: 645127:CKROP_RS02370
uniprot id: C4LHF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

645127:CKROP RS07170
gene id: 645127:CKROP_RS07170
uniprot id: C4LK25
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

645127:CKROP RS00570
gene id: 645127:CKROP_RS00570
uniprot id: C4LG71
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

645127:CKROP RS05050
gene id: 645127:CKROP_RS05050
uniprot id: C4LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS02365
gene id: 645127:CKROP_RS02365
uniprot id: C4LHF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

645127:CKROP RS02070
gene id: 645127:CKROP_RS02070
uniprot id: C4LH97
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

645127:CKROP RS03860
gene id: 645127:CKROP_RS03860
uniprot id: C4LI88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

645127:CKROP RS01835
gene id: 645127:CKROP_RS01835
uniprot id: C4LH55
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS06685
gene id: 645127:CKROP_RS06685
uniprot id: C4LJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

645127:CKROP RS03910
gene id: 645127:CKROP_RS03910
uniprot id: C4LI98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

645127:CKROP RS04055
gene id: 645127:CKROP_RS04055
uniprot id: C4LIC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

645127:CKROP RS08925
gene id: 645127:CKROP_RS08925
uniprot id: C4LL25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS00690
gene id: 645127:CKROP_RS00690
uniprot id: C4LG79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

645127:CKROP RS03160
gene id: 645127:CKROP_RS03160
uniprot id: C4LHV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

645127:CKROP RS03785
gene id: 645127:CKROP_RS03785
uniprot id: C4LI72
names: Similarity
messages: Belongs to the IMPACT family.

645127:CKROP RS09720
gene id: 645127:CKROP_RS09720
uniprot id: C4LLI0
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

645127:CKROP RS08850
gene id: 645127:CKROP_RS08850
uniprot id: C4LL10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

645127:CKROP RS09920
gene id: 645127:CKROP_RS09920
uniprot id: C4LLM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645127:CKROP RS04245
gene id: 645127:CKROP_RS04245
uniprot id: C4LIG2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

645127:CKROP RS02315
gene id: 645127:CKROP_RS02315
uniprot id: C4LHE2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

645127:CKROP RS06195
gene id: 645127:CKROP_RS06195
uniprot id: C4LJJ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

645127:CKROP RS09505
gene id: 645127:CKROP_RS09505
uniprot id: C4LLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

645127:CKROP RS08435
gene id: 645127:CKROP_RS08435
uniprot id: C4LKS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

645127:CKROP RS09030
gene id: 645127:CKROP_RS09030
uniprot id: C4LL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

645127:CKROP RS06275
gene id: 645127:CKROP_RS06275
uniprot id: C4LJK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

645127:CKROP RS05610
gene id: 645127:CKROP_RS05610
uniprot id: C4LJ77
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

645127:CKROP RS04205
gene id: 645127:CKROP_RS04205
uniprot id: C4LIF4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

645127:CKROP RS04130
gene id: 645127:CKROP_RS04130
uniprot id: C4LIE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

645127:CKROP RS10905
gene id: 645127:CKROP_RS10905
uniprot id: C4LL96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

645127:CKROP RS00485
gene id: 645127:CKROP_RS00485
uniprot id: C4LG54
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04805
gene id: 645127:CKROP_RS04805
uniprot id: C4LIS3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

645127:CKROP RS02825
gene id: 645127:CKROP_RS02825
uniprot id: C4LHN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645127:CKROP RS07245
gene id: 645127:CKROP_RS07245
uniprot id: C4LK37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS08785
gene id: 645127:CKROP_RS08785
uniprot id: C4LKZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

645127:CKROP RS04885
gene id: 645127:CKROP_RS04885
uniprot id: C4LIT9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

645127:CKROP RS04145
gene id: 645127:CKROP_RS04145
uniprot id: C4LIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS08185
gene id: 645127:CKROP_RS08185
uniprot id: C4LKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

645127:CKROP RS01615
gene id: 645127:CKROP_RS01615
uniprot id: C4LH13
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

645127:CKROP RS00030
gene id: 645127:CKROP_RS00030
uniprot id: C4LGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

645127:CKROP RS10995
gene id: 645127:CKROP_RS10995
uniprot id: C4LGI4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645127:CKROP RS00865
gene id: 645127:CKROP_RS00865
uniprot id: C4LGL0
names: Similarity
messages: Belongs to the CFA/CMAS family.

645127:CKROP RS07160
gene id: 645127:CKROP_RS07160
uniprot id: C4LK23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

645127:CKROP RS01940
gene id: 645127:CKROP_RS01940
uniprot id: C4LH76
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

645127:CKROP RS02880
gene id: 645127:CKROP_RS02880
uniprot id: C4LHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

645127:CKROP RS06560
gene id: 645127:CKROP_RS06560
uniprot id: C4LJR3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

645127:CKROP RS01075
gene id: 645127:CKROP_RS01075
uniprot id: C4LGQ3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

645127:CKROP RS00185
gene id: 645127:CKROP_RS00185
uniprot id: C4LGD8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

645127:CKROP RS03420
gene id: 645127:CKROP_RS03420
uniprot id: C4LI01
names: Similarity
messages: Belongs to the glutamine synthetase family.

645127:CKROP RS05355
gene id: 645127:CKROP_RS05355
uniprot id: C4LJ29
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS01080
gene id: 645127:CKROP_RS01080
uniprot id: C4LGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

645127:CKROP RS01215
gene id: 645127:CKROP_RS01215
uniprot id: C4LGT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS10190
gene id: 645127:CKROP_RS10190
uniprot id: C4LGF8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

645127:CKROP RS03595
gene id: 645127:CKROP_RS03595
uniprot id: C4LI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

645127:CKROP RS09700
gene id: 645127:CKROP_RS09700
uniprot id: C4LLH6
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS09270
gene id: 645127:CKROP_RS09270
uniprot id: C4LL93
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

645127:CKROP RS07270
gene id: 645127:CKROP_RS07270
uniprot id: C4LK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

645127:CKROP RS08795
gene id: 645127:CKROP_RS08795
uniprot id: C4LKZ9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

645127:CKROP RS04965
gene id: 645127:CKROP_RS04965
uniprot id: C4LIV5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

645127:CKROP RS03655
gene id: 645127:CKROP_RS03655
uniprot id: C4LI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

645127:CKROP RS06865
gene id: 645127:CKROP_RS06865
uniprot id: C4LJX0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

645127:CKROP RS05315
gene id: 645127:CKROP_RS05315
uniprot id: C4LJ20
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

645127:CKROP RS10045
gene id: 645127:CKROP_RS10045
uniprot id: C4LLP4
names: Similarity
messages: Belongs to the EfeM/EfeO family.

645127:CKROP RS05280
gene id: 645127:CKROP_RS05280
uniprot id: C4LJ13
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645127:CKROP RS06235
gene id: 645127:CKROP_RS06235
uniprot id: C4LJK0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

645127:CKROP RS09870
gene id: 645127:CKROP_RS09870
uniprot id: C4LLL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

645127:CKROP RS04680
gene id: 645127:CKROP_RS04680
uniprot id: C4LIP8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

645127:CKROP RS11595
gene id: 645127:CKROP_RS11595
uniprot id: C4LKS0
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

645127:CKROP RS03075
gene id: 645127:CKROP_RS03075
uniprot id: C4LHT6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

645127:CKROP RS03410
gene id: 645127:CKROP_RS03410
uniprot id: C4LHZ9
names: Similarity
messages: Belongs to the TPP enzyme family.

645127:CKROP RS00845
gene id: 645127:CKROP_RS00845
uniprot id: C4LGK6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

645127:CKROP RS00600
gene id: 645127:CKROP_RS00600
uniprot id: C4LLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

645127:CKROP RS08800
gene id: 645127:CKROP_RS08800
uniprot id: C4LL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

645127:CKROP RS04185
gene id: 645127:CKROP_RS04185
uniprot id: C4LIF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS05090
gene id: 645127:CKROP_RS05090
uniprot id: C4LIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

645127:CKROP RS08285
gene id: 645127:CKROP_RS08285
uniprot id: C4LKP6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

645127:CKROP RS00915
gene id: 645127:CKROP_RS00915
uniprot id: C4LGM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS10200
gene id: 645127:CKROP_RS10200
uniprot id: C4LGG0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS09040
gene id: 645127:CKROP_RS09040
uniprot id: C4LL48
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

645127:CKROP RS00575
gene id: 645127:CKROP_RS00575
uniprot id: C4LG72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

645127:CKROP RS00015
gene id: 645127:CKROP_RS00015
uniprot id: C4LGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

645127:CKROP RS09430
gene id: 645127:CKROP_RS09430
uniprot id: C4LLC2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

645127:CKROP RS01665
gene id: 645127:CKROP_RS01665
uniprot id: C4LH23
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

645127:CKROP RS01950
gene id: 645127:CKROP_RS01950
uniprot id: C4LH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

645127:CKROP RS00165
gene id: 645127:CKROP_RS00165
uniprot id: C4LGD4
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

645127:CKROP RS08130
gene id: 645127:CKROP_RS08130
uniprot id: C4LKL5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

645127:CKROP RS06955
gene id: 645127:CKROP_RS06955
uniprot id: C4LJY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

645127:CKROP RS06365
gene id: 645127:CKROP_RS06365
uniprot id: C4LJM5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

645127:CKROP RS00645
gene id: 645127:CKROP_RS00645
uniprot id: C4LLR8
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS02860
gene id: 645127:CKROP_RS02860
uniprot id: C4LHP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

645127:CKROP RS02890
gene id: 645127:CKROP_RS02890
uniprot id: C4LHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645127:CKROP RS04135
gene id: 645127:CKROP_RS04135
uniprot id: C4LIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

645127:CKROP RS05635
gene id: 645127:CKROP_RS05635
uniprot id: C4LJ82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

645127:CKROP RS05375
gene id: 645127:CKROP_RS05375
uniprot id: C4LJ33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

645127:CKROP RS00925
gene id: 645127:CKROP_RS00925
uniprot id: C4LGM2
names: Similarity
messages: Belongs to the catalase family.

645127:CKROP RS02220
gene id: 645127:CKROP_RS02220
uniprot id: C4LHC4
names: Subcellular Location Annotation
messages: Cell membrane

645127:CKROP RS04945
gene id: 645127:CKROP_RS04945
uniprot id: C4LIV1
names: Similarity
messages: Belongs to the peptidase A24 family.

645127:CKROP RS06090
gene id: 645127:CKROP_RS06090
uniprot id: C4LJH1
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07005
gene id: 645127:CKROP_RS07005
uniprot id: C4LJZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

645127:CKROP RS08240
gene id: 645127:CKROP_RS08240
uniprot id: C4LKN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

645127:CKROP RS03660
gene id: 645127:CKROP_RS03660
uniprot id: C4LI47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

645127:CKROP RS05830
gene id: 645127:CKROP_RS05830
uniprot id: C4LJC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

645127:CKROP RS09015
gene id: 645127:CKROP_RS09015
uniprot id: C4LL43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

645127:CKROP RS02815
gene id: 645127:CKROP_RS02815
uniprot id: C4LHN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS09620
gene id: 645127:CKROP_RS09620
uniprot id: C4LLG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645127:CKROP RS08210
gene id: 645127:CKROP_RS08210
uniprot id: C4LKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

645127:CKROP RS00405
gene id: 645127:CKROP_RS00405
uniprot id: C4LG41
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

645127:CKROP RS04890
gene id: 645127:CKROP_RS04890
uniprot id: C4LIU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

645127:CKROP RS06805
gene id: 645127:CKROP_RS06805
uniprot id: C4LJW1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

645127:CKROP RS01550
gene id: 645127:CKROP_RS01550
uniprot id: C4LH00
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

645127:CKROP RS10250
gene id: 645127:CKROP_RS10250
uniprot id: C4LGH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS01400
gene id: 645127:CKROP_RS01400
uniprot id: C4LGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS07025
gene id: 645127:CKROP_RS07025
uniprot id: C4LJZ8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

645127:CKROP RS05575
gene id: 645127:CKROP_RS05575
uniprot id: C4LJ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS00890
gene id: 645127:CKROP_RS00890
uniprot id: C4LGL5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645127:CKROP RS02295
gene id: 645127:CKROP_RS02295
uniprot id: C4LHD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

645127:CKROP RS03435
gene id: 645127:CKROP_RS03435
uniprot id: C4LI04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

645127:CKROP RS05310
gene id: 645127:CKROP_RS05310
uniprot id: C4LJ19
names: Similarity
messages: Belongs to the neocarzinostatin family.

645127:CKROP RS06610
gene id: 645127:CKROP_RS06610
uniprot id: C4LJS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS09125
gene id: 645127:CKROP_RS09125
uniprot id: C4LL66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

645127:CKROP RS01140
gene id: 645127:CKROP_RS01140
uniprot id: C4LGR6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645127:CKROP RS06585
gene id: 645127:CKROP_RS06585
uniprot id: C4LJR8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

645127:CKROP RS04330
gene id: 645127:CKROP_RS04330
uniprot id: C4LIH8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

645127:CKROP RS04990
gene id: 645127:CKROP_RS04990
uniprot id: C4LIW0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

645127:CKROP RS03385
gene id: 645127:CKROP_RS03385
uniprot id: C4LHZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

645127:CKROP RS09915
gene id: 645127:CKROP_RS09915
uniprot id: C4LLM2
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04140
gene id: 645127:CKROP_RS04140
uniprot id: C4LIE3
names: Similarity
messages: Belongs to the UPF0434 family.

645127:CKROP RS04250
gene id: 645127:CKROP_RS04250
uniprot id: C4LIG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

645127:CKROP RS01525
gene id: 645127:CKROP_RS01525
uniprot id: C4LGZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645127:CKROP RS01300
gene id: 645127:CKROP_RS01300
uniprot id: C4LGU8
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS09150
gene id: 645127:CKROP_RS09150
uniprot id: C4LL71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645127:CKROP RS09420
gene id: 645127:CKROP_RS09420
uniprot id: C4LLC0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645127:CKROP RS03310
gene id: 645127:CKROP_RS03310
uniprot id: C4LHY0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

645127:CKROP RS06640
gene id: 645127:CKROP_RS06640
uniprot id: C4LJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

645127:CKROP RS08260
gene id: 645127:CKROP_RS08260
uniprot id: C4LKP1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

645127:CKROP RS06120
gene id: 645127:CKROP_RS06120
uniprot id: C4LJH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

645127:CKROP RS09190
gene id: 645127:CKROP_RS09190
uniprot id: C4LL80
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

645127:CKROP RS10030
gene id: 645127:CKROP_RS10030
uniprot id: C4LLP1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

645127:CKROP RS04405
gene id: 645127:CKROP_RS04405
uniprot id: C4LIJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS01455
gene id: 645127:CKROP_RS01455
uniprot id: C4LGX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

645127:CKROP RS01595
gene id: 645127:CKROP_RS01595
uniprot id: C4LH09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06515
gene id: 645127:CKROP_RS06515
uniprot id: C4LJQ4
names: Similarity
messages: Belongs to the Fur family.

645127:CKROP RS06965
gene id: 645127:CKROP_RS06965
uniprot id: C4LJY7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

645127:CKROP RS10340
gene id: 645127:CKROP_RS10340
uniprot id: C4LGI7
names: Similarity
messages: Belongs to the thioredoxin family.

645127:CKROP RS04590
gene id: 645127:CKROP_RS04590
uniprot id: C4LIN1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

645127:CKROP RS06290
gene id: 645127:CKROP_RS06290
uniprot id: C4LJL0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

645127:CKROP RS09625
gene id: 645127:CKROP_RS09625
uniprot id: C4LLG2
names: Cofactor
messages: Can also use Mn(2+) ion.

645127:CKROP RS05290
gene id: 645127:CKROP_RS05290
uniprot id: C4LJ15
names: Similarity
messages: Belongs to the neocarzinostatin family.

645127:CKROP RS05345
gene id: 645127:CKROP_RS05345
uniprot id: C4LJ26
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

645127:CKROP RS01640
gene id: 645127:CKROP_RS01640
uniprot id: C4LH18
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

645127:CKROP RS01425
gene id: 645127:CKROP_RS01425
uniprot id: C4LGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

645127:CKROP RS07935
gene id: 645127:CKROP_RS07935
uniprot id: C4LKH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

645127:CKROP RS06385
gene id: 645127:CKROP_RS06385
uniprot id: C4LJN0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

645127:CKROP RS08630
gene id: 645127:CKROP_RS08630
uniprot id: C4LKW4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

645127:CKROP RS01920
gene id: 645127:CKROP_RS01920
uniprot id: C4LH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

645127:CKROP RS05785
gene id: 645127:CKROP_RS05785
uniprot id: C4LJB3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

645127:CKROP RS07085
gene id: 645127:CKROP_RS07085
uniprot id: C4LK09
names: Similarity
messages: Belongs to the phosphohexose mutase family.

645127:CKROP RS03750
gene id: 645127:CKROP_RS03750
uniprot id: C4LI65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

645127:CKROP RS06295
gene id: 645127:CKROP_RS06295
uniprot id: C4LJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

645127:CKROP RS08845
gene id: 645127:CKROP_RS08845
uniprot id: C4LL09
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

645127:CKROP RS05885
gene id: 645127:CKROP_RS05885
uniprot id: C4LJD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

645127:CKROP RS06545
gene id: 645127:CKROP_RS06545
uniprot id: C4LJR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

645127:CKROP RS00530
gene id: 645127:CKROP_RS00530
uniprot id: C4LG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

645127:CKROP RS01975
gene id: 645127:CKROP_RS01975
uniprot id: C4LH82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

645127:CKROP RS01235
gene id: 645127:CKROP_RS01235
uniprot id: C4LGT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS00470
gene id: 645127:CKROP_RS00470
uniprot id: C4LG52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS07030
gene id: 645127:CKROP_RS07030
uniprot id: C4LJZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

645127:CKROP RS03700
gene id: 645127:CKROP_RS03700
uniprot id: C4LI55
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

645127:CKROP RS06325
gene id: 645127:CKROP_RS06325
uniprot id: C4LJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

645127:CKROP RS01365
gene id: 645127:CKROP_RS01365
uniprot id: C4LGW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

645127:CKROP RS09045
gene id: 645127:CKROP_RS09045
uniprot id: C4LL49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

645127:CKROP RS09025
gene id: 645127:CKROP_RS09025
uniprot id: C4LL45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS03135
gene id: 645127:CKROP_RS03135
uniprot id: C4LHU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

645127:CKROP RS07650
gene id: 645127:CKROP_RS07650
uniprot id: C4LKC0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

645127:CKROP RS04095
gene id: 645127:CKROP_RS04095
uniprot id: C4LID4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645127:CKROP RS03875
gene id: 645127:CKROP_RS03875
uniprot id: C4LI91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

645127:CKROP RS00725
gene id: 645127:CKROP_RS00725
uniprot id: C4LG86
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

645127:CKROP RS03180
gene id: 645127:CKROP_RS03180
uniprot id: C4LHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

645127:CKROP RS06785
gene id: 645127:CKROP_RS06785
uniprot id: C4LJV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

645127:CKROP RS05900
gene id: 645127:CKROP_RS05900
uniprot id: C4LJD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

645127:CKROP RS02050
gene id: 645127:CKROP_RS02050
uniprot id: C4LH93
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

645127:CKROP RS04500
gene id: 645127:CKROP_RS04500
uniprot id: C4LIL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

645127:CKROP RS10300
gene id: 645127:CKROP_RS10300
uniprot id: C4LGI0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

645127:CKROP RS05540
gene id: 645127:CKROP_RS05540
uniprot id: C4LJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

645127:CKROP RS05605
gene id: 645127:CKROP_RS05605
uniprot id: C4LJ76
names: Similarity
messages: Belongs to the ribF family.

645127:CKROP RS05500
gene id: 645127:CKROP_RS05500
uniprot id: C4LJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

645127:CKROP RS01945
gene id: 645127:CKROP_RS01945
uniprot id: C4LH77
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS02390
gene id: 645127:CKROP_RS02390
uniprot id: C4LHF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

645127:CKROP RS07655
gene id: 645127:CKROP_RS07655
uniprot id: C4LKC1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

645127:CKROP RS08330
gene id: 645127:CKROP_RS08330
uniprot id: C4LKQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

645127:CKROP RS08355
gene id: 645127:CKROP_RS08355
uniprot id: C4LKR0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

645127:CKROP RS09395
gene id: 645127:CKROP_RS09395
uniprot id: C4LLB6
names: Subcellular Location Annotation
messages: Cell membrane

645127:CKROP RS05075
gene id: 645127:CKROP_RS05075
uniprot id: C4LIX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

645127:CKROP RS03965
gene id: 645127:CKROP_RS03965
uniprot id: C4LIA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645127:CKROP RS00335
gene id: 645127:CKROP_RS00335
uniprot id: C4LLT6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

645127:CKROP RS01085
gene id: 645127:CKROP_RS01085
uniprot id: C4LGQ5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

645127:CKROP RS07215
gene id: 645127:CKROP_RS07215
uniprot id: C4LK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

645127:CKROP RS08750
gene id: 645127:CKROP_RS08750
uniprot id: C4LKZ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

645127:CKROP RS02375
gene id: 645127:CKROP_RS02375
uniprot id: C4LHF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

645127:CKROP RS04875
gene id: 645127:CKROP_RS04875
uniprot id: C4LIT7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

645127:CKROP RS05890
gene id: 645127:CKROP_RS05890
uniprot id: C4LJD4
names: Similarity
messages: Belongs to the acylphosphatase family.

645127:CKROP RS04565
gene id: 645127:CKROP_RS04565
uniprot id: C4LIM6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

645127:CKROP RS04125
gene id: 645127:CKROP_RS04125
uniprot id: C4LIE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

645127:CKROP RS06760
gene id: 645127:CKROP_RS06760
uniprot id: C4LJV4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

645127:CKROP RS05750
gene id: 645127:CKROP_RS05750
uniprot id: C4LJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

645127:CKROP RS03495
gene id: 645127:CKROP_RS03495
uniprot id: C4LI16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS09685
gene id: 645127:CKROP_RS09685
uniprot id: C4LLH3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

645127:CKROP RS00045
gene id: 645127:CKROP_RS00045
uniprot id: C4LGB8
names: Similarity
messages: Belongs to the arginase family.

645127:CKROP RS05285
gene id: 645127:CKROP_RS05285
uniprot id: C4LJ14
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS04265
gene id: 645127:CKROP_RS04265
uniprot id: C4LIG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

645127:CKROP RS05335
gene id: 645127:CKROP_RS05335
uniprot id: C4LJ24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645127:CKROP RS07430
gene id: 645127:CKROP_RS07430
uniprot id: C4LK75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

645127:CKROP RS03510
gene id: 645127:CKROP_RS03510
uniprot id: C4LI19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

645127:CKROP RS02395
gene id: 645127:CKROP_RS02395
uniprot id: C4LHF6
names: Similarity
messages: Belongs to the peptidase S1C family.

645127:CKROP RS09230
gene id: 645127:CKROP_RS09230
uniprot id: C4LL89
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

645127:CKROP RS03490
gene id: 645127:CKROP_RS03490
uniprot id: C4LI15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

645127:CKROP RS08835
gene id: 645127:CKROP_RS08835
uniprot id: C4LL07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS04235
gene id: 645127:CKROP_RS04235
uniprot id: C4LIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS08375
gene id: 645127:CKROP_RS08375
uniprot id: C4LKR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS02305
gene id: 645127:CKROP_RS02305
uniprot id: C4LHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

645127:CKROP RS03355
gene id: 645127:CKROP_RS03355
uniprot id: C4LHY8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

645127:CKROP RS07785
gene id: 645127:CKROP_RS07785
uniprot id: C4LKE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS03820
gene id: 645127:CKROP_RS03820
uniprot id: C4LI80
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

645127:CKROP RS03740
gene id: 645127:CKROP_RS03740
uniprot id: C4LI63
names: Similarity
messages: Belongs to the asparaginase 1 family.

645127:CKROP RS09305
gene id: 645127:CKROP_RS09305
uniprot id: C4LL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

645127:CKROP RS01465
gene id: 645127:CKROP_RS01465
uniprot id: C4LGY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06330
gene id: 645127:CKROP_RS06330
uniprot id: C4LJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

645127:CKROP RS03690
gene id: 645127:CKROP_RS03690
uniprot id: C4LI53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

645127:CKROP RS02470
gene id: 645127:CKROP_RS02470
uniprot id: C4LHH0
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS03480
gene id: 645127:CKROP_RS03480
uniprot id: C4LI13
names: Similarity
messages: Belongs to the asparagine synthetase family.

645127:CKROP RS07790
gene id: 645127:CKROP_RS07790
uniprot id: C4LKE8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

645127:CKROP RS06530
gene id: 645127:CKROP_RS06530
uniprot id: C4LJQ7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

645127:CKROP RS09485
gene id: 645127:CKROP_RS09485
uniprot id: C4LLD4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

645127:CKROP RS07165
gene id: 645127:CKROP_RS07165
uniprot id: C4LK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

645127:CKROP RS02255
gene id: 645127:CKROP_RS02255
uniprot id: C4LHD0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645127:CKROP RS09225
gene id: 645127:CKROP_RS09225
uniprot id: C4LL88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

645127:CKROP RS04190
gene id: 645127:CKROP_RS04190
uniprot id: C4LIF1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

645127:CKROP RS03335
gene id: 645127:CKROP_RS03335
uniprot id: C4LHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

645127:CKROP RS06705
gene id: 645127:CKROP_RS06705
uniprot id: C4LJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS04065
gene id: 645127:CKROP_RS04065
uniprot id: C4LIC8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645127:CKROP RS03635
gene id: 645127:CKROP_RS03635
uniprot id: C4LI42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

645127:CKROP RS04820
gene id: 645127:CKROP_RS04820
uniprot id: C4LIS6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

645127:CKROP RS04490
gene id: 645127:CKROP_RS04490
uniprot id: C4LIL1
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

645127:CKROP RS02995
gene id: 645127:CKROP_RS02995
uniprot id: C4LHS0
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04930
gene id: 645127:CKROP_RS04930
uniprot id: C4LIU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06285
gene id: 645127:CKROP_RS06285
uniprot id: C4LJK9
names: Similarity
messages: Belongs to the UPF0045 family.

645127:CKROP RS06815
gene id: 645127:CKROP_RS06815
uniprot id: C4LJW3
names: Similarity
messages: Belongs to the peptidase M1 family.

645127:CKROP RS10620
gene id: 645127:CKROP_RS10620
uniprot id: C4LHX3
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS08115
gene id: 645127:CKROP_RS08115
uniprot id: C4LKL2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645127:CKROP RS08855
gene id: 645127:CKROP_RS08855
uniprot id: C4LL11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

645127:CKROP RS00010
gene id: 645127:CKROP_RS00010
uniprot id: C4LGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

645127:CKROP RS07730
gene id: 645127:CKROP_RS07730
uniprot id: C4LKD6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

645127:CKROP RS06525
gene id: 645127:CKROP_RS06525
uniprot id: C4LJQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

645127:CKROP RS00005
gene id: 645127:CKROP_RS00005
uniprot id: C4LGB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

645127:CKROP RS04900
gene id: 645127:CKROP_RS04900
uniprot id: C4LIU2
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

645127:CKROP RS04100
gene id: 645127:CKROP_RS04100
uniprot id: C4LID5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

645127:CKROP RS06380
gene id: 645127:CKROP_RS06380
uniprot id: C4LJM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

645127:CKROP RS02450
gene id: 645127:CKROP_RS02450
uniprot id: C4LHG7
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS05620
gene id: 645127:CKROP_RS05620
uniprot id: C4LJ79
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS00695
gene id: 645127:CKROP_RS00695
uniprot id: C4LG80
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS02380
gene id: 645127:CKROP_RS02380
uniprot id: C4LHF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

645127:CKROP RS08825
gene id: 645127:CKROP_RS08825
uniprot id: C4LL05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS03730
gene id: 645127:CKROP_RS03730
uniprot id: C4LI61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

645127:CKROP RS08180
gene id: 645127:CKROP_RS08180
uniprot id: C4LKM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

645127:CKROP RS05970
gene id: 645127:CKROP_RS05970
uniprot id: C4LJF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

645127:CKROP RS08840
gene id: 645127:CKROP_RS08840
uniprot id: C4LL08
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS07370
gene id: 645127:CKROP_RS07370
uniprot id: C4LK61
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

645127:CKROP RS06175
gene id: 645127:CKROP_RS06175
uniprot id: C4LJI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS02570
gene id: 645127:CKROP_RS02570
uniprot id: C4LHJ0
names: Similarity
messages: Belongs to the peptidase C1 family.

645127:CKROP RS03415
gene id: 645127:CKROP_RS03415
uniprot id: C4LI00
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

645127:CKROP RS00105
gene id: 645127:CKROP_RS00105
uniprot id: C4LGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

645127:CKROP RS06245
gene id: 645127:CKROP_RS06245
uniprot id: C4LJK2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

645127:CKROP RS00930
gene id: 645127:CKROP_RS00930
uniprot id: C4LGM3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

645127:CKROP RS04985
gene id: 645127:CKROP_RS04985
uniprot id: C4LIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

645127:CKROP RS08670
gene id: 645127:CKROP_RS08670
uniprot id: C4LKX3
names: Similarity
messages: Belongs to the WXG100 family.

645127:CKROP RS07745
gene id: 645127:CKROP_RS07745
uniprot id: C4LKD9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

645127:CKROP RS01315
gene id: 645127:CKROP_RS01315
uniprot id: C4LGV0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

645127:CKROP RS04575
gene id: 645127:CKROP_RS04575
uniprot id: C4LIM8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

645127:CKROP RS00715
gene id: 645127:CKROP_RS00715
uniprot id: C4LG84
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

645127:CKROP RS06110
gene id: 645127:CKROP_RS06110
uniprot id: C4LJH5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

645127:CKROP RS03425
gene id: 645127:CKROP_RS03425
uniprot id: C4LI02
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07565
gene id: 645127:CKROP_RS07565
uniprot id: C4LKA3
names: Similarity
messages: Belongs to the AccD/PCCB family.

645127:CKROP RS06770
gene id: 645127:CKROP_RS06770
uniprot id: C4LJV6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

645127:CKROP RS05080
gene id: 645127:CKROP_RS05080
uniprot id: C4LIX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

645127:CKROP RS08830
gene id: 645127:CKROP_RS08830
uniprot id: C4LL06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

645127:CKROP RS10150
gene id: 645127:CKROP_RS10150
uniprot id: C4LGF1
names: Similarity
messages: Belongs to the thioredoxin family.

645127:CKROP RS06905
gene id: 645127:CKROP_RS06905
uniprot id: C4LJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

645127:CKROP RS09195
gene id: 645127:CKROP_RS09195
uniprot id: C4LL82
names: Similarity
messages: Belongs to the DapA family.

645127:CKROP RS06160
gene id: 645127:CKROP_RS06160
uniprot id: C4LJI5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

645127:CKROP RS06870
gene id: 645127:CKROP_RS06870
uniprot id: C4LJX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645127:CKROP RS09780
gene id: 645127:CKROP_RS09780
uniprot id: C4LLJ2
names: Subcellular Location Annotation
messages: Cytoplasm

645127:CKROP RS01405
gene id: 645127:CKROP_RS01405
uniprot id: C4LGW9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

645127:CKROP RS06205
gene id: 645127:CKROP_RS06205
uniprot id: C4LJJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

645127:CKROP RS09565
gene id: 645127:CKROP_RS09565
uniprot id: C4LLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

645127:CKROP RS07490
gene id: 645127:CKROP_RS07490
uniprot id: C4LK88
names: Similarity
messages: Belongs to the phosphohexose mutase family.

645127:CKROP RS04610
gene id: 645127:CKROP_RS04610
uniprot id: C4LIN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS02715
gene id: 645127:CKROP_RS02715
uniprot id: C4LHL7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

645127:CKROP RS02535
gene id: 645127:CKROP_RS02535
uniprot id: C4LHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

645127:CKROP RS05725
gene id: 645127:CKROP_RS05725
uniprot id: C4LJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

645127:CKROP RS02580
gene id: 645127:CKROP_RS02580
uniprot id: C4LHJ2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

645127:CKROP RS03665
gene id: 645127:CKROP_RS03665
uniprot id: C4LI48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

645127:CKROP RS05755
gene id: 645127:CKROP_RS05755
uniprot id: C4LJA7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS08125
gene id: 645127:CKROP_RS08125
uniprot id: C4LKL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS00040
gene id: 645127:CKROP_RS00040
uniprot id: C4LGB7
names: Similarity
messages: Belongs to the peptidase M18 family.

645127:CKROP RS09360
gene id: 645127:CKROP_RS09360
uniprot id: C4LLB0
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04895
gene id: 645127:CKROP_RS04895
uniprot id: C4LIU1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

645127:CKROP RS03015
gene id: 645127:CKROP_RS03015
uniprot id: C4LHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

645127:CKROP RS08155
gene id: 645127:CKROP_RS08155
uniprot id: C4LKM0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

645127:CKROP RS10675
gene id: 645127:CKROP_RS10675
uniprot id: C4LIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

645127:CKROP RS03630
gene id: 645127:CKROP_RS03630
uniprot id: C4LI41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

645127:CKROP RS05840
gene id: 645127:CKROP_RS05840
uniprot id: C4LJC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

645127:CKROP RS01260
gene id: 645127:CKROP_RS01260
uniprot id: C4LGU0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

645127:CKROP RS09020
gene id: 645127:CKROP_RS09020
uniprot id: C4LL44
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

645127:CKROP RS05705
gene id: 645127:CKROP_RS05705
uniprot id: C4LJ97
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS07335
gene id: 645127:CKROP_RS07335
uniprot id: C4LK54
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

645127:CKROP RS06845
gene id: 645127:CKROP_RS06845
uniprot id: C4LJW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645127:CKROP RS06240
gene id: 645127:CKROP_RS06240
uniprot id: C4LJK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

645127:CKROP RS00065
gene id: 645127:CKROP_RS00065
uniprot id: C4LGA5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

645127:CKROP RS00375
gene id: 645127:CKROP_RS00375
uniprot id: C4LLV0
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS06535
gene id: 645127:CKROP_RS06535
uniprot id: C4LJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

645127:CKROP RS09110
gene id: 645127:CKROP_RS09110
uniprot id: C4LL63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

645127:CKROP RS05710
gene id: 645127:CKROP_RS05710
uniprot id: C4LJ98
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

645127:CKROP RS09345
gene id: 645127:CKROP_RS09345
uniprot id: C4LLA7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

645127:CKROP RS11685
gene id: 645127:CKROP_RS11685
uniprot id: C4LIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

645127:CKROP RS04370
gene id: 645127:CKROP_RS04370
uniprot id: C4LII6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

645127:CKROP RS04955
gene id: 645127:CKROP_RS04955
uniprot id: C4LIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

645127:CKROP RS02895
gene id: 645127:CKROP_RS02895
uniprot id: C4LHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645127:CKROP RS03290
gene id: 645127:CKROP_RS03290
uniprot id: C4LHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

645127:CKROP RS09705
gene id: 645127:CKROP_RS09705
uniprot id: C4LLH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645127:CKROP RS07535
gene id: 645127:CKROP_RS07535
uniprot id: C4LK97
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS05675
gene id: 645127:CKROP_RS05675
uniprot id: C4LJ91
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

645127:CKROP RS00225
gene id: 645127:CKROP_RS00225
uniprot id: C4LLS4
names: Similarity
messages: Belongs to the AccD/PCCB family.

645127:CKROP RS05745
gene id: 645127:CKROP_RS05745
uniprot id: C4LJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

645127:CKROP RS05005
gene id: 645127:CKROP_RS05005
uniprot id: C4LIW3
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS00785
gene id: 645127:CKROP_RS00785
uniprot id: C4LG97
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

645127:CKROP RS07810
gene id: 645127:CKROP_RS07810
uniprot id: C4LKF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

645127:CKROP RS04315
gene id: 645127:CKROP_RS04315
uniprot id: C4LIH5
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS00190
gene id: 645127:CKROP_RS00190
uniprot id: C4LGD9
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS10700
gene id: 645127:CKROP_RS10700
uniprot id: C4LIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

645127:CKROP RS01060
gene id: 645127:CKROP_RS01060
uniprot id: C4LGQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

645127:CKROP RS06310
gene id: 645127:CKROP_RS06310
uniprot id: C4LJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

645127:CKROP RS03445
gene id: 645127:CKROP_RS03445
uniprot id: C4LI06
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

645127:CKROP RS05120
gene id: 645127:CKROP_RS05120
uniprot id: C4LIY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645127:CKROP RS06650
gene id: 645127:CKROP_RS06650
uniprot id: C4LJT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

645127:CKROP RS01545
gene id: 645127:CKROP_RS01545
uniprot id: C4LGZ9
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

645127:CKROP RS00685
gene id: 645127:CKROP_RS00685
uniprot id: C4LG78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

645127:CKROP RS06185
gene id: 645127:CKROP_RS06185
uniprot id: C4LJJ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

645127:CKROP RS03995
gene id: 645127:CKROP_RS03995
uniprot id: C4LIB4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

645127:CKROP RS10375
gene id: 645127:CKROP_RS10375
uniprot id: C4LGJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

645127:CKROP RS07015
gene id: 645127:CKROP_RS07015
uniprot id: C4LJZ6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

645127:CKROP RS02650
gene id: 645127:CKROP_RS02650
uniprot id: C4LHK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06340
gene id: 645127:CKROP_RS06340
uniprot id: C4LJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

645127:CKROP RS02345
gene id: 645127:CKROP_RS02345
uniprot id: C4LHE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

645127:CKROP RS08395
gene id: 645127:CKROP_RS08395
uniprot id: C4LKR7
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

645127:CKROP RS03650
gene id: 645127:CKROP_RS03650
uniprot id: C4LI45
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS05560
gene id: 645127:CKROP_RS05560
uniprot id: C4LJ68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS03245
gene id: 645127:CKROP_RS03245
uniprot id: C4LHX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

645127:CKROP RS01125
gene id: 645127:CKROP_RS01125
uniprot id: C4LGR3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

645127:CKROP RS05555
gene id: 645127:CKROP_RS05555
uniprot id: C4LJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

645127:CKROP RS03530
gene id: 645127:CKROP_RS03530
uniprot id: C4LI22
names: Similarity
messages: Belongs to the peptidase C40 family.

645127:CKROP RS04850
gene id: 645127:CKROP_RS04850
uniprot id: C4LIT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

645127:CKROP RS09350
gene id: 645127:CKROP_RS09350
uniprot id: C4LLA8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

645127:CKROP RS05670
gene id: 645127:CKROP_RS05670
uniprot id: C4LJ90
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645127:CKROP RS06190
gene id: 645127:CKROP_RS06190
uniprot id: C4LJJ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

645127:CKROP RS03095
gene id: 645127:CKROP_RS03095
uniprot id: C4LHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

645127:CKROP RS08150
gene id: 645127:CKROP_RS08150
uniprot id: C4LKL9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

645127:CKROP RS03465
gene id: 645127:CKROP_RS03465
uniprot id: C4LI10
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

645127:CKROP RS05940
gene id: 645127:CKROP_RS05940
uniprot id: C4LJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

645127:CKROP RS07425
gene id: 645127:CKROP_RS07425
uniprot id: C4LK74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

645127:CKROP RS06690
gene id: 645127:CKROP_RS06690
uniprot id: C4LJU0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

645127:CKROP RS02970
gene id: 645127:CKROP_RS02970
uniprot id: C4LHR5
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS04090
gene id: 645127:CKROP_RS04090
uniprot id: C4LID3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645127:CKROP RS04075
gene id: 645127:CKROP_RS04075
uniprot id: C4LID0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

645127:CKROP RS06740
gene id: 645127:CKROP_RS06740
uniprot id: C4LJV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

645127:CKROP RS04485
gene id: 645127:CKROP_RS04485
uniprot id: C4LIL0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

645127:CKROP RS09300
gene id: 645127:CKROP_RS09300
uniprot id: C4LL98
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06880
gene id: 645127:CKROP_RS06880
uniprot id: C4LJX3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

645127:CKROP RS07400
gene id: 645127:CKROP_RS07400
uniprot id: C4LK68
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS05000
gene id: 645127:CKROP_RS05000
uniprot id: C4LIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

645127:CKROP RS06370
gene id: 645127:CKROP_RS06370
uniprot id: C4LJM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS00255
gene id: 645127:CKROP_RS00255
uniprot id: C4LLS9
names: Similarity
messages: Belongs to the glutamate synthase family.

645127:CKROP RS05660
gene id: 645127:CKROP_RS05660
uniprot id: C4LJ88
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

645127:CKROP RS08860
gene id: 645127:CKROP_RS08860
uniprot id: C4LL12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

645127:CKROP RS01680
gene id: 645127:CKROP_RS01680
uniprot id: C4LH26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645127:CKROP RS10385
gene id: 645127:CKROP_RS10385
uniprot id: C4LGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

645127:CKROP RS09835
gene id: 645127:CKROP_RS09835
uniprot id: C4LLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Membrane

645127:CKROP RS06520
gene id: 645127:CKROP_RS06520
uniprot id: C4LJQ5
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS06490
gene id: 645127:CKROP_RS06490
uniprot id: C4LJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

645127:CKROP RS00465
gene id: 645127:CKROP_RS00465
uniprot id: C4LG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645127:CKROP RS05645
gene id: 645127:CKROP_RS05645
uniprot id: C4LJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

645127:CKROP RS00060
gene id: 645127:CKROP_RS00060
uniprot id: C4LGA4
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS03340
gene id: 645127:CKROP_RS03340
uniprot id: C4LHY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

645127:CKROP RS01930
gene id: 645127:CKROP_RS01930
uniprot id: C4LH74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

645127:CKROP RS07460
gene id: 645127:CKROP_RS07460
uniprot id: C4LK81
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

645127:CKROP RS06830
gene id: 645127:CKROP_RS06830
uniprot id: C4LJW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

645127:CKROP RS09335
gene id: 645127:CKROP_RS09335
uniprot id: C4LLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

645127:CKROP RS07710
gene id: 645127:CKROP_RS07710
uniprot id: C4LKD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS00210
gene id: 645127:CKROP_RS00210
uniprot id: C4LLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

645127:CKROP RS05045
gene id: 645127:CKROP_RS05045
uniprot id: C4LIX1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

645127:CKROP RS08755
gene id: 645127:CKROP_RS08755
uniprot id: C4LKZ1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

645127:CKROP RS01270
gene id: 645127:CKROP_RS01270
uniprot id: C4LGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

645127:CKROP RS09120
gene id: 645127:CKROP_RS09120
uniprot id: C4LL65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

645127:CKROP RS08560
gene id: 645127:CKROP_RS08560
uniprot id: C4LKV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

645127:CKROP RS09630
gene id: 645127:CKROP_RS09630
uniprot id: C4LLG3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

645127:CKROP RS05715
gene id: 645127:CKROP_RS05715
uniprot id: C4LJ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

645127:CKROP RS10175
gene id: 645127:CKROP_RS10175
uniprot id: C4LGF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645127:CKROP RS05760
gene id: 645127:CKROP_RS05760
uniprot id: C4LJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

645127:CKROP RS03675
gene id: 645127:CKROP_RS03675
uniprot id: C4LI50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645127:CKROP RS06305
gene id: 645127:CKROP_RS06305
uniprot id: C4LJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

645127:CKROP RS07320
gene id: 645127:CKROP_RS07320
uniprot id: C4LK51
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

645127:CKROP RS09055
gene id: 645127:CKROP_RS09055
uniprot id: C4LL51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

645127:CKROP RS07755
gene id: 645127:CKROP_RS07755
uniprot id: C4LKE1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645127:CKROP RS03400
gene id: 645127:CKROP_RS03400
uniprot id: C4LHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

645127:CKROP RS01310
gene id: 645127:CKROP_RS01310
uniprot id: C4LGU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

645127:CKROP RS10890
gene id: 645127:CKROP_RS10890
uniprot id: C4LL68
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS00025
gene id: 645127:CKROP_RS00025
uniprot id: C4LGB4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

645127:CKROP RS02780
gene id: 645127:CKROP_RS02780
uniprot id: C4LHM8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

645127:CKROP RS07800
gene id: 645127:CKROP_RS07800
uniprot id: C4LKF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

645127:CKROP RS03605
gene id: 645127:CKROP_RS03605
uniprot id: C4LI36
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645127:CKROP RS06115
gene id: 645127:CKROP_RS06115
uniprot id: C4LJH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

645127:CKROP RS02615
gene id: 645127:CKROP_RS02615
uniprot id: C4LHJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

645127:CKROP RS00355
gene id: 645127:CKROP_RS00355
uniprot id: C4LLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

645127:CKROP RS04470
gene id: 645127:CKROP_RS04470
uniprot id: C4LIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

645127:CKROP RS06230
gene id: 645127:CKROP_RS06230
uniprot id: C4LJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

645127:CKROP RS05385
gene id: 645127:CKROP_RS05385
uniprot id: C4LJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

645127:CKROP RS07385
gene id: 645127:CKROP_RS07385
uniprot id: C4LK65
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

645127:CKROP RS09185
gene id: 645127:CKROP_RS09185
uniprot id: C4LL79
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

645127:CKROP RS04510
gene id: 645127:CKROP_RS04510
uniprot id: C4LIL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

645127:CKROP RS09035
gene id: 645127:CKROP_RS09035
uniprot id: C4LL47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

645127:CKROP RS01825
gene id: 645127:CKROP_RS01825
uniprot id: C4LH52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645127:CKROP RS04775
gene id: 645127:CKROP_RS04775
uniprot id: C4LIR7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

645127:CKROP RS09155
gene id: 645127:CKROP_RS09155
uniprot id: C4LL72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

645127:CKROP RS00410
gene id: 645127:CKROP_RS00410
uniprot id: C4LG42
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

645127:CKROP RS05790
gene id: 645127:CKROP_RS05790
uniprot id: C4LJB4
names: Similarity
messages: Belongs to the UPF0102 family.

645127:CKROP RS00295
gene id: 645127:CKROP_RS00295
uniprot id: C4LLU8
names: Subcellular Location Annotation
messages: Membrane

645127:CKROP RS06720
gene id: 645127:CKROP_RS06720
uniprot id: C4LJU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.