644223:PAS chr3 0781
gene id: 644223:PAS_chr3_0781
uniprot id: C4R5J9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

644223:PAS chr3 0732
gene id: 644223:PAS_chr3_0732
uniprot id: C4R5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

644223:PAS c131 0009
gene id: 644223:PAS_c131_0009
uniprot id: C4R387
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0593
gene id: 644223:PAS_chr4_0593
uniprot id: C4R8C8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

644223:PAS chr4 0518
gene id: 644223:PAS_chr4_0518
uniprot id: C4R848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

644223:PAS FragD 0012
gene id: 644223:PAS_FragD_0012
uniprot id: C4R9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

644223:PAS chr2-1 0856
gene id: 644223:PAS_chr2-1_0856
uniprot id: C4R0Y1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr1-4 0147
gene id: 644223:PAS_chr1-4_0147
uniprot id: C4QXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

644223:PAS chr2-1 0180
gene id: 644223:PAS_chr2-1_0180
uniprot id: C4QZW5
names: Similarity
messages: Belongs to the dopey family.

644223:PAS chr4 0262
gene id: 644223:PAS_chr4_0262
uniprot id: C4R7C1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

644223:PAS chr3 0271
gene id: 644223:PAS_chr3_0271
uniprot id: C4R424
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0106
gene id: 644223:PAS_chr3_0106
uniprot id: C4R3K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

644223:PAS chr4 0555
gene id: 644223:PAS_chr4_0555
uniprot id: C4R890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

644223:PAS chr3 0116
gene id: 644223:PAS_chr3_0116
uniprot id: C4R3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0467
gene id: 644223:PAS_chr1-1_0467
uniprot id: C4QVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

644223:PAS chr2-2 0466
gene id: 644223:PAS_chr2-2_0466
uniprot id: C4R2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr3 1168
gene id: 644223:PAS_chr3_1168
uniprot id: C4R3Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0466
gene id: 644223:PAS_chr3_0466
uniprot id: C4R4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0280
gene id: 644223:PAS_chr4_0280
uniprot id: C4R7D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

644223:PAS chr2-1 0545
gene id: 644223:PAS_chr2-1_0545
uniprot id: C4R104
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

644223:PAS chr4 0445
gene id: 644223:PAS_chr4_0445
uniprot id: C4R7X3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

644223:PAS chr4 0201
gene id: 644223:PAS_chr4_0201
uniprot id: C4R751
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr3 0903
gene id: 644223:PAS_chr3_0903
uniprot id: C4R5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

644223:PAS chr4 0314
gene id: 644223:PAS_chr4_0314
uniprot id: C4R7I0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

644223:PAS chr2-1 0054
gene id: 644223:PAS_chr2-1_0054
uniprot id: C4QZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr1-1 0127
gene id: 644223:PAS_chr1-1_0127
uniprot id: C4QW65
names: Similarity
messages: Belongs to the peptidase M20A family.

644223:PAS chr3 1072
gene id: 644223:PAS_chr3_1072
uniprot id: C4R6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C1D family.
messages: Nucleus
messages: Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.

644223:PAS chr1-1 0357
gene id: 644223:PAS_chr1-1_0357
uniprot id: C4QWW0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr1-4 0455
gene id: 644223:PAS_chr1-4_0455
uniprot id: C4QYI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

644223:PAS chr3 0880
gene id: 644223:PAS_chr3_0880
uniprot id: C4R5V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

644223:PAS chr2-1 0563
gene id: 644223:PAS_chr2-1_0563
uniprot id: C4R124
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

644223:PAS chr4 0559
gene id: 644223:PAS_chr4_0559
uniprot id: C4R894
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

644223:PAS chr2-1 0787
gene id: 644223:PAS_chr2-1_0787
uniprot id: C4R1S1
names: Similarity
messages: Belongs to the multicopper oxidase family.

644223:PAS chr1-3 0137
gene id: 644223:PAS_chr1-3_0137
uniprot id: C4QVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

644223:PAS chr1-1 0237
gene id: 644223:PAS_chr1-1_0237
uniprot id: C4QWI3
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

644223:PAS chr2-2 0249
gene id: 644223:PAS_chr2-2_0249
uniprot id: C4R2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0777
gene id: 644223:PAS_chr2-1_0777
uniprot id: C4R1Q9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

644223:PAS chr3 0410
gene id: 644223:PAS_chr3_0410
uniprot id: C4R4H3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr3 1081
gene id: 644223:PAS_chr3_1081
uniprot id: C4R6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0455
gene id: 644223:PAS_chr1-1_0455
uniprot id: C4QX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

644223:PAS chr1-1 0172
gene id: 644223:PAS_chr1-1_0172
uniprot id: C4QWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

644223:PAS chr3 0609
gene id: 644223:PAS_chr3_0609
uniprot id: C4R520
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

644223:PAS chr1-4 0226
gene id: 644223:PAS_chr1-4_0226
uniprot id: C4QXT7
names: Similarity
messages: Belongs to the GST superfamily.

644223:PAS chr2-1 0051
gene id: 644223:PAS_chr2-1_0051
uniprot id: C4QZH8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

644223:PAS chr2-1 0533
gene id: 644223:PAS_chr2-1_0533
uniprot id: C4R0Z2
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

644223:PAS chr4 0394
gene id: 644223:PAS_chr4_0394
uniprot id: C4R7R9
names: Similarity
messages: Belongs to the NXF family.

644223:PAS chr4 0679
gene id: 644223:PAS_chr4_0679
uniprot id: C4R8L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

644223:PAS chr1-4 0009
gene id: 644223:PAS_chr1-4_0009
uniprot id: C4QX69
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

644223:PAS chr2-1 0085
gene id: 644223:PAS_chr2-1_0085
uniprot id: C4QZL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-2 0378
gene id: 644223:PAS_chr2-2_0378
uniprot id: C4R203
names: Similarity
messages: Belongs to the PAT1 family.

644223:PAS chr2-1 0357
gene id: 644223:PAS_chr2-1_0357
uniprot id: C4R0F3
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr3 0881
gene id: 644223:PAS_chr3_0881
uniprot id: C4R5V2
names: Similarity
messages: Belongs to the AAA ATPase family.

644223:PAS chr4 0658
gene id: 644223:PAS_chr4_0658
uniprot id: C4R8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

644223:PAS chr4 0520
gene id: 644223:PAS_chr4_0520
uniprot id: C4R850
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0349
gene id: 644223:PAS_chr1-1_0349
uniprot id: C4QWV2
names: Similarity
messages: Belongs to the RRP7 family.

644223:PAS chr2-2 0287
gene id: 644223:PAS_chr2-2_0287
uniprot id: C4R299
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

644223:PAS chr4 0771
gene id: 644223:PAS_chr4_0771
uniprot id: C4R8W0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

644223:PAS chr1-4 0235
gene id: 644223:PAS_chr1-4_0235
uniprot id: C4QXU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

644223:PAS chr2-2 0380
gene id: 644223:PAS_chr2-2_0380
uniprot id: C4R201
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr1-1 0059
gene id: 644223:PAS_chr1-1_0059
uniprot id: C4QVZ4
names: Similarity
messages: Belongs to the TFIIB family.

644223:PAS chr2-2 0238
gene id: 644223:PAS_chr2-2_0238
uniprot id: C4R2F4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr4 0764
gene id: 644223:PAS_chr4_0764
uniprot id: C4R8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

644223:PAS chr3 1186
gene id: 644223:PAS_chr3_1186
uniprot id: C4R4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

644223:PAS chr4 0526
gene id: 644223:PAS_chr4_0526
uniprot id: C4R855
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

644223:PAS chr2-1 0351
gene id: 644223:PAS_chr2-1_0351
uniprot id: C4R0E7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0190
gene id: 644223:PAS_chr1-1_0190
uniprot id: C4QWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

644223:PAS chr4 0980
gene id: 644223:PAS_chr4_0980
uniprot id: C4R8K1
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0505
gene id: 644223:PAS_chr4_0505
uniprot id: C4R836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

644223:PAS chr2-2 0486
gene id: 644223:PAS_chr2-2_0486
uniprot id: C4R2A5
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

644223:PAS chr4 0323
gene id: 644223:PAS_chr4_0323
uniprot id: C4R7J1
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

644223:PAS chr1-4 0063
gene id: 644223:PAS_chr1-4_0063
uniprot id: C4QXC0
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

644223:PAS chr2-2 0184
gene id: 644223:PAS_chr2-2_0184
uniprot id: C4R2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

644223:PAS chr4 0536
gene id: 644223:PAS_chr4_0536
uniprot id: C4R871
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0423
gene id: 644223:PAS_chr4_0423
uniprot id: C4R7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

644223:PAS chr1-4 0198
gene id: 644223:PAS_chr1-4_0198
uniprot id: C4QXQ8
names: Similarity
messages: Belongs to the pantothenate synthetase family.

644223:PAS chr1-1 0048
gene id: 644223:PAS_chr1-1_0048
uniprot id: C4QVY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr4 0131
gene id: 644223:PAS_chr4_0131
uniprot id: C4R6Y3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

644223:PAS chr1-1 0220
gene id: 644223:PAS_chr1-1_0220
uniprot id: C4QWG7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0310
gene id: 644223:PAS_chr1-4_0310
uniprot id: C4QY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
messages: Homodimer.
messages: Preautophagosomal structure

644223:PAS FragB 0004
gene id: 644223:PAS_FragB_0004
uniprot id: C4QZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

644223:PAS chr2-1 0214
gene id: 644223:PAS_chr2-1_0214
uniprot id: C4QZZ8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-3 0187
gene id: 644223:PAS_chr1-3_0187
uniprot id: C4QVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

644223:PAS chr4 0125
gene id: 644223:PAS_chr4_0125
uniprot id: C4R6X7
names: Similarity
messages: Belongs to the MAD2 family.

644223:PAS chr3 0876
gene id: 644223:PAS_chr3_0876
uniprot id: C4R5U7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

644223:PAS chr3 1032
gene id: 644223:PAS_chr3_1032
uniprot id: C4R6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

644223:PAS chr2-1 0370
gene id: 644223:PAS_chr2-1_0370
uniprot id: C4R0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

644223:PAS chr4 0818
gene id: 644223:PAS_chr4_0818
uniprot id: C4R914
names: Similarity
messages: Belongs to the UPP synthase family.

644223:PAS chr1-4 0566
gene id: 644223:PAS_chr1-4_0566
uniprot id: C4QYU8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

644223:PAS chr2-2 0087
gene id: 644223:PAS_chr2-2_0087
uniprot id: C4R2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

644223:PAS chr3 1093
gene id: 644223:PAS_chr3_1093
uniprot id: C4R6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

644223:PAS chr2-2 0467
gene id: 644223:PAS_chr2-2_0467
uniprot id: C4R2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

644223:PAS chr2-1 0397
gene id: 644223:PAS_chr2-1_0397
uniprot id: C4R0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

644223:PAS chr3 0651
gene id: 644223:PAS_chr3_0651
uniprot id: C4R562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

644223:PAS chr4 0204
gene id: 644223:PAS_chr4_0204
uniprot id: C4R755
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0303
gene id: 644223:PAS_chr1-4_0303
uniprot id: C4QY20
names: Similarity
messages: Belongs to the HMBS family.

644223:PAS chr2-1 0778
gene id: 644223:PAS_chr2-1_0778
uniprot id: C4R1R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

644223:PAS chr1-3 0141
gene id: 644223:PAS_chr1-3_0141
uniprot id: C4QVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

644223:PAS chr3 1163
gene id: 644223:PAS_chr3_1163
uniprot id: C4R3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

644223:PAS chr1-4 0680
gene id: 644223:PAS_chr1-4_0680
uniprot id: C4QYE9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

644223:PAS chr3 0131
gene id: 644223:PAS_chr3_0131
uniprot id: C4R3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

644223:PAS chr1-4 0374
gene id: 644223:PAS_chr1-4_0374
uniprot id: C4QY96
names: Similarity
messages: Belongs to the TRM112 family.

644223:PAS chr2-1 0136
gene id: 644223:PAS_chr2-1_0136
uniprot id: C4QZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

644223:PAS chr3 1084
gene id: 644223:PAS_chr3_1084
uniprot id: C4R6G5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

644223:PAS chr4 0602
gene id: 644223:PAS_chr4_0602
uniprot id: C4R8D7
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy. Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways. Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole. Binds palmytoyl-CoA but not oleyl-CoA.
messages: Belongs to the ATG37 family.
messages: Interacts with ATG30 and PEX3.
messages: Peroxisome membrane
messages: Phosphorylated.
messages: Repressed in glucose and ethanol media, but induced under peroxisome proliferation conditions in methanol and oleate media.

644223:PAS chr2-1 0039
gene id: 644223:PAS_chr2-1_0039
uniprot id: C4QZG5
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

644223:PAS chr2-1 0012
gene id: 644223:PAS_chr2-1_0012
uniprot id: C4QZD7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0944
gene id: 644223:PAS_chr4_0944
uniprot id: C4R7H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).
messages: Belongs to the complex I LYR family. MZM1 subfamily.
messages: Interacts with RIP1.
messages: Mitochondrion matrix

644223:PAS chr2-2 0254
gene id: 644223:PAS_chr2-2_0254
uniprot id: C4R2D6
names: Similarity
messages: Belongs to the MGMT family.

644223:PAS chr4 0544
gene id: 644223:PAS_chr4_0544
uniprot id: C4R879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0344
gene id: 644223:PAS_chr2-1_0344
uniprot id: C4R0D9
names: Similarity
messages: Belongs to the PET191 family.

644223:PAS chr3 0652
gene id: 644223:PAS_chr3_0652
uniprot id: C4R563
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

644223:PAS chr1-4 0570
gene id: 644223:PAS_chr1-4_0570
uniprot id: C4QYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0554
gene id: 644223:PAS_chr2-1_0554
uniprot id: C4R114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

644223:PAS chr4 0475
gene id: 644223:PAS_chr4_0475
uniprot id: C4R806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

644223:PAS chr3 0774
gene id: 644223:PAS_chr3_0774
uniprot id: C4R5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

644223:PAS chr3 0708
gene id: 644223:PAS_chr3_0708
uniprot id: C4R5C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

644223:PAS chr3 0980
gene id: 644223:PAS_chr3_0980
uniprot id: C4R658
names: Subcellular Location Annotation
messages: Membrane
messages: Preautophagosomal structure membrane

644223:PAS chr2-1 0553
gene id: 644223:PAS_chr2-1_0553
uniprot id: C4R113
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0398
gene id: 644223:PAS_chr4_0398
uniprot id: C4R7S3
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

644223:PAS chr1-1 0301
gene id: 644223:PAS_chr1-1_0301
uniprot id: C4QWQ5
names: Similarity
messages: Belongs to the UPP synthase family.

644223:PAS chr4 0471
gene id: 644223:PAS_chr4_0471
uniprot id: C4R7Z8
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT family.
messages: Beta-mannosyltransferase involved in cell wall biosynthesis. Responsible for addition of a hexose to the beta-mannose chain. Beta-mannosylation catalyzed by BMT4 masks beta-mannose epitopes recognized by monoclonal antibody (mAb) 5B2 reacting with beta-1,2-linked mannobiose as a minimal epitope.
messages: Leads to a size reduction of glycans resistant to alpha-mannosidase treatment.
messages: Membrane

644223:PAS FragB 0007
gene id: 644223:PAS_FragB_0007
uniprot id: C4QZ64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VTS1 family.
messages: Monomer. Binds to RNA.
messages: P-body
messages: cytosol

644223:PAS chr3 0568
gene id: 644223:PAS_chr3_0568
uniprot id: C4R4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

644223:PAS chr3 0871
gene id: 644223:PAS_chr3_0871
uniprot id: C4R5U2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0227
gene id: 644223:PAS_chr2-2_0227
uniprot id: C4R2G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

644223:PAS chr1-4 0116
gene id: 644223:PAS_chr1-4_0116
uniprot id: C4QXH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

644223:PAS chr2-2 0028
gene id: 644223:PAS_chr2-2_0028
uniprot id: C4R336
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0437
gene id: 644223:PAS_chr1-4_0437
uniprot id: C4QYG4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

644223:PAS chr2-1 0217
gene id: 644223:PAS_chr2-1_0217
uniprot id: C4R003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

644223:PAS chr1-4 0239
gene id: 644223:PAS_chr1-4_0239
uniprot id: C4QXV1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

644223:PAS chr2-2 0049
gene id: 644223:PAS_chr2-2_0049
uniprot id: C4R311
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-70 and Arg-73) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.

644223:PAS chr3 0465
gene id: 644223:PAS_chr3_0465
uniprot id: C4R4M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

644223:PAS chr2-2 0129
gene id: 644223:PAS_chr2-2_0129
uniprot id: C4R2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

644223:PAS chr3 0263
gene id: 644223:PAS_chr3_0263
uniprot id: C4R415
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

644223:PAS chr2-2 0288
gene id: 644223:PAS_chr2-2_0288
uniprot id: C4R298
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

644223:PAS chr1-1 0263
gene id: 644223:PAS_chr1-1_0263
uniprot id: C4QWL1
names: Similarity
messages: Belongs to the actin family.

644223:PAS chr3 0936
gene id: 644223:PAS_chr3_0936
uniprot id: C4R611
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

644223:PAS chr2-2 0163
gene id: 644223:PAS_chr2-2_0163
uniprot id: C4R2N8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

644223:PAS chr4 0844
gene id: 644223:PAS_chr4_0844
uniprot id: C4R938
names: Similarity
messages: Belongs to the protein disulfide isomerase family.

644223:PAS chr1-4 0326
gene id: 644223:PAS_chr1-4_0326
uniprot id: C4QY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

644223:PAS chr1-4 0096
gene id: 644223:PAS_chr1-4_0096
uniprot id: C4QXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

644223:PAS chr3 1138
gene id: 644223:PAS_chr3_1138
uniprot id: C4R373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

644223:PAS c121 0018
gene id: 644223:PAS_c121_0018
uniprot id: C4QZ43
names: Similarity
messages: Belongs to the RCAN family.

644223:PAS chr1-1 0295
gene id: 644223:PAS_chr1-1_0295
uniprot id: C4QWP8
names: Function
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family.
messages: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.

644223:PAS chr3 0923
gene id: 644223:PAS_chr3_0923
uniprot id: C4R5Z5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0625
gene id: 644223:PAS_chr2-1_0625
uniprot id: C4R192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family.
messages: Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
messages: Prevacuolar compartment membrane
messages: trans-Golgi network membrane

644223:PAS chr1-4 0047
gene id: 644223:PAS_chr1-4_0047
uniprot id: C4QXA5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterododecamer of 4 alpha, 4 beta and 4 gamma chains. The gamma chain bridges the N-terminal halves of the alpha and beta subunits (By similarity).

644223:PAS chr2-2 0393
gene id: 644223:PAS_chr2-2_0393
uniprot id: C4R1Z1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

644223:PAS chr4 0709
gene id: 644223:PAS_chr4_0709
uniprot id: C4R8P5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr4 0937
gene id: 644223:PAS_chr4_0937
uniprot id: C4R7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

644223:PAS chr1-4 0385
gene id: 644223:PAS_chr1-4_0385
uniprot id: C4QYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

644223:PAS chr1-4 0444
gene id: 644223:PAS_chr1-4_0444
uniprot id: C4QYH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

644223:PAS chr2-1 0742
gene id: 644223:PAS_chr2-1_0742
uniprot id: C4R1L8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0153
gene id: 644223:PAS_chr2-1_0153
uniprot id: C4QZT6
names: Similarity
messages: Belongs to the RAD52 family.

644223:PAS chr2-1 0679
gene id: 644223:PAS_chr2-1_0679
uniprot id: C4R1F2
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

644223:PAS chr2-2 0145
gene id: 644223:PAS_chr2-2_0145
uniprot id: C4R2Q6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

644223:PAS chr1-3 0225
gene id: 644223:PAS_chr1-3_0225
uniprot id: C4QVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

644223:PAS chr3 0987
gene id: 644223:PAS_chr3_0987
uniprot id: C4R664
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr2-2 0270
gene id: 644223:PAS_chr2-2_0270
uniprot id: C4R2C0
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

644223:PAS chr3 1177
gene id: 644223:PAS_chr3_1177
uniprot id: C4R492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OCA5 family.
messages: Cytoplasm

644223:PAS chr4 0916
gene id: 644223:PAS_chr4_0916
uniprot id: C4R6R1
names: Similarity
messages: Belongs to the COG3 family.

644223:PAS chr4 0049
gene id: 644223:PAS_chr4_0049
uniprot id: C4R6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0366
gene id: 644223:PAS_chr2-1_0366
uniprot id: C4R0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

644223:PAS chr2-1 0542
gene id: 644223:PAS_chr2-1_0542
uniprot id: C4R101
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr4 0069
gene id: 644223:PAS_chr4_0069
uniprot id: C4R6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

644223:PAS chr1-1 0450
gene id: 644223:PAS_chr1-1_0450
uniprot id: C4QX54
names: Similarity
messages: Belongs to the DCC1 family.

644223:PAS chr4 0118
gene id: 644223:PAS_chr4_0118
uniprot id: C4R6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

644223:PAS chr2-1 0327
gene id: 644223:PAS_chr2-1_0327
uniprot id: C4R0C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-3 0138
gene id: 644223:PAS_chr1-3_0138
uniprot id: C4QVC5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr3 0731
gene id: 644223:PAS_chr3_0731
uniprot id: C4R5E4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS chr2-1 0771
gene id: 644223:PAS_chr2-1_0771
uniprot id: C4R1Q2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

644223:PAS chr4 0830
gene id: 644223:PAS_chr4_0830
uniprot id: C4R924
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

644223:PAS chr2-1 0298
gene id: 644223:PAS_chr2-1_0298
uniprot id: C4R088
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

644223:PAS chr4 0192
gene id: 644223:PAS_chr4_0192
uniprot id: C4R742
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr1-4 0093
gene id: 644223:PAS_chr1-4_0093
uniprot id: C4QXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane

644223:PAS chr2-2 0341
gene id: 644223:PAS_chr2-2_0341
uniprot id: C4R241
names: Similarity
messages: Belongs to the peptidase M67A family.

644223:PAS chr3 0831
gene id: 644223:PAS_chr3_0831
uniprot id: C4R5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

644223:PAS chr1-4 0225
gene id: 644223:PAS_chr1-4_0225
uniprot id: C4QXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

644223:PAS chr1-3 0111
gene id: 644223:PAS_chr1-3_0111
uniprot id: C4QV98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

644223:PAS chr1-4 0277
gene id: 644223:PAS_chr1-4_0277
uniprot id: C4QXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

644223:PAS chr1-1 0207
gene id: 644223:PAS_chr1-1_0207
uniprot id: C4QWF2
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

644223:PAS chr2-2 0185
gene id: 644223:PAS_chr2-2_0185
uniprot id: C4R2L1
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

644223:PAS chr4 0468
gene id: 644223:PAS_chr4_0468
uniprot id: C4R7Z5
names: Similarity
messages: Belongs to the MT-A70-like family.

644223:PAS chr3 0188
gene id: 644223:PAS_chr3_0188
uniprot id: C4R3T2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

644223:PAS chr1-4 0204
gene id: 644223:PAS_chr1-4_0204
uniprot id: C4QXR4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

644223:PAS chr1-1 0389
gene id: 644223:PAS_chr1-1_0389
uniprot id: C4QWZ3
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

644223:PAS chr1-4 0656
gene id: 644223:PAS_chr1-4_0656
uniprot id: C4QXK0
names: Similarity
messages: Belongs to the peptidase M20A family.

644223:PAS chr1-4 0675
gene id: 644223:PAS_chr1-4_0675
uniprot id: C4QYB5
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

644223:PAS chr2-1 0780
gene id: 644223:PAS_chr2-1_0780
uniprot id: C4R1R3
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

644223:PAS chr1-4 0451
gene id: 644223:PAS_chr1-4_0451
uniprot id: C4QYH9
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr3 0233
gene id: 644223:PAS_chr3_0233
uniprot id: C4R3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

644223:PAS chr1-4 0040
gene id: 644223:PAS_chr1-4_0040
uniprot id: C4QX98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

644223:PAS chr3 0360
gene id: 644223:PAS_chr3_0360
uniprot id: C4R4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

644223:PAS chr1-1 0363
gene id: 644223:PAS_chr1-1_0363
uniprot id: C4QWW6
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

644223:PAS chr1-4 0450
gene id: 644223:PAS_chr1-4_0450
uniprot id: C4QYH8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

644223:PAS chr3 0754
gene id: 644223:PAS_chr3_0754
uniprot id: C4R5G8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr2-2 0067
gene id: 644223:PAS_chr2-2_0067
uniprot id: C4R2Z1
names: Similarity
messages: Belongs to the CAP family.

644223:PAS chr3 1057
gene id: 644223:PAS_chr3_1057
uniprot id: C4R6D3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

644223:PAS chr3 0389
gene id: 644223:PAS_chr3_0389
uniprot id: C4R4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

644223:PAS chr2-1 0067
gene id: 644223:PAS_chr2-1_0067
uniprot id: C4QZJ4
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

644223:PAS chr3 0137
gene id: 644223:PAS_chr3_0137
uniprot id: C4R3N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

644223:PAS chr1-4 0508
gene id: 644223:PAS_chr1-4_0508
uniprot id: C4QYN7
names: Similarity
messages: Belongs to the VAC14 family.

644223:PAS chr1-1 0288
gene id: 644223:PAS_chr1-1_0288
uniprot id: C4QWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr3 0036
gene id: 644223:PAS_chr3_0036
uniprot id: C4R3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0298
gene id: 644223:PAS_chr4_0298
uniprot id: C4R7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

644223:PAS chr2-1 0119
gene id: 644223:PAS_chr2-1_0119
uniprot id: C4QZP9
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

644223:PAS chr3 1126
gene id: 644223:PAS_chr3_1126
uniprot id: C4R6K7
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

644223:PAS chr2-2 0434
gene id: 644223:PAS_chr2-2_0434
uniprot id: C4R1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr4 0453
gene id: 644223:PAS_chr4_0453
uniprot id: C4R7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

644223:PAS chr1-4 0360
gene id: 644223:PAS_chr1-4_0360
uniprot id: C4QY80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

644223:PAS chr1-1 0243
gene id: 644223:PAS_chr1-1_0243
uniprot id: C4QWJ0
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

644223:PAS chr3 1194
gene id: 644223:PAS_chr3_1194
uniprot id: C4R4Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS FragB 0012
gene id: 644223:PAS_FragB_0012
uniprot id: C4QZ69
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

644223:PAS chr4 0198
gene id: 644223:PAS_chr4_0198
uniprot id: C4R749
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

644223:PAS chr1-4 0632
gene id: 644223:PAS_chr1-4_0632
uniprot id: C4QZ19
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

644223:PAS chr2-1 0097
gene id: 644223:PAS_chr2-1_0097
uniprot id: C4QZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

644223:PAS chr3 1102
gene id: 644223:PAS_chr3_1102
uniprot id: C4R6I2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0896
gene id: 644223:PAS_chr4_0896
uniprot id: C4R991
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0207
gene id: 644223:PAS_chr1-3_0207
uniprot id: C4QVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

644223:PAS chr2-2 0291
gene id: 644223:PAS_chr2-2_0291
uniprot id: C4R294
names: Similarity
messages: Belongs to the small Tim family.

644223:PAS chr1-1 0231
gene id: 644223:PAS_chr1-1_0231
uniprot id: C4QWH7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0169
gene id: 644223:PAS_chr1-1_0169
uniprot id: C4QWB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0080
gene id: 644223:PAS_chr1-1_0080
uniprot id: C4QW16
names: Similarity
messages: Belongs to the MUB1/samB family.

644223:PAS chr1-1 0281
gene id: 644223:PAS_chr1-1_0281
uniprot id: C4QWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

644223:PAS chr3 0443
gene id: 644223:PAS_chr3_0443
uniprot id: C4R4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

644223:PAS chr3 0289
gene id: 644223:PAS_chr3_0289
uniprot id: C4R443
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

644223:PAS chr1-3 0122
gene id: 644223:PAS_chr1-3_0122
uniprot id: C4QVA9
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

644223:PAS chr3 1118
gene id: 644223:PAS_chr3_1118
uniprot id: C4R6J9
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr2-1 0398
gene id: 644223:PAS_chr2-1_0398
uniprot id: C4R0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

644223:PAS chr2-1 0219
gene id: 644223:PAS_chr2-1_0219
uniprot id: C4R005
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-1 0358
gene id: 644223:PAS_chr1-1_0358
uniprot id: C4QWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

644223:PAS chr4 0418
gene id: 644223:PAS_chr4_0418
uniprot id: C4R7U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

644223:PAS chr1-4 0117
gene id: 644223:PAS_chr1-4_0117
uniprot id: C4QXH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

644223:PAS FragB 0061
gene id: 644223:PAS_FragB_0061
uniprot id: C4QZB8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

644223:PAS chr4 0826
gene id: 644223:PAS_chr4_0826
uniprot id: C4R920
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

644223:PAS chr4 0060
gene id: 644223:PAS_chr4_0060
uniprot id: C4R6R0
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

644223:PAS chr1-3 0157
gene id: 644223:PAS_chr1-3_0157
uniprot id: C4QVE5
names: Similarity
messages: Belongs to the DCP1 family.

644223:PAS chr1-1 0408
gene id: 644223:PAS_chr1-1_0408
uniprot id: C4QX12
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr2-1 0749
gene id: 644223:PAS_chr2-1_0749
uniprot id: C4R1M6
names: Similarity
messages: Belongs to the allantoicase family.

644223:PAS chr2-2 0334
gene id: 644223:PAS_chr2-2_0334
uniprot id: C4R248
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

644223:PAS chr3 0581
gene id: 644223:PAS_chr3_0581
uniprot id: C4R4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

644223:PAS chr3 1205
gene id: 644223:PAS_chr3_1205
uniprot id: C4R545
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

644223:PAS chr2-1 0689
gene id: 644223:PAS_chr2-1_0689
uniprot id: C4R1G2
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr3 0303
gene id: 644223:PAS_chr3_0303
uniprot id: C4R458
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr1-1 0213
gene id: 644223:PAS_chr1-1_0213
uniprot id: C4QWF9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0877
gene id: 644223:PAS_chr4_0877
uniprot id: C4R972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-2 0338
gene id: 644223:PAS_chr2-2_0338
uniprot id: C4R244
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.

644223:PAS chr2-2 0310
gene id: 644223:PAS_chr2-2_0310
uniprot id: C4R272
names: Similarity
messages: Belongs to the peptidase S9B family.

644223:PAS chr3 0039
gene id: 644223:PAS_chr3_0039
uniprot id: C4R3D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

644223:PAS chr1-1 0226
gene id: 644223:PAS_chr1-1_0226
uniprot id: C4QWH2
names: Similarity
messages: Belongs to the peptidase S8 family.

644223:PAS chr4 0372
gene id: 644223:PAS_chr4_0372
uniprot id: C4R7P2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0833
gene id: 644223:PAS_chr2-1_0833
uniprot id: C4R0M1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

644223:PAS chr2-1 0330
gene id: 644223:PAS_chr2-1_0330
uniprot id: C4R0C5
names: Similarity
messages: Belongs to the SGT1 family.

644223:PAS chr2-1 0291
gene id: 644223:PAS_chr2-1_0291
uniprot id: C4R080
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr2-1 0089
gene id: 644223:PAS_chr2-1_0089
uniprot id: C4QZL6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

644223:PAS chr3 0927
gene id: 644223:PAS_chr3_0927
uniprot id: C4R600
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

644223:PAS chr3 0371
gene id: 644223:PAS_chr3_0371
uniprot id: C4R4C9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

644223:PAS chr1-4 0611
gene id: 644223:PAS_chr1-4_0611
uniprot id: C4QYZ6
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

644223:PAS chr1-4 0511
gene id: 644223:PAS_chr1-4_0511
uniprot id: C4QYN9
names: Similarity
messages: Belongs to the peptidase M16 family.

644223:PAS chr1-4 0405
gene id: 644223:PAS_chr1-4_0405
uniprot id: C4QYD0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

644223:PAS chr2-2 0229
gene id: 644223:PAS_chr2-2_0229
uniprot id: C4R2G4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

644223:PAS chr2-2 0425
gene id: 644223:PAS_chr2-2_0425
uniprot id: C4R1W0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

644223:PAS chr3 0482
gene id: 644223:PAS_chr3_0482
uniprot id: C4R4P4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

644223:PAS chr1-4 0175
gene id: 644223:PAS_chr1-4_0175
uniprot id: C4QXN6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

644223:PAS chr3 0130
gene id: 644223:PAS_chr3_0130
uniprot id: C4R3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0312
gene id: 644223:PAS_chr3_0312
uniprot id: C4R466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

644223:PAS chr1-3 0017
gene id: 644223:PAS_chr1-3_0017
uniprot id: C4QUZ9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0357
gene id: 644223:PAS_chr3_0357
uniprot id: C4R4B3
names: Disruption Phenotype
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the final step in the biosynthesis of the membrane lipid glucosylceramide (GluCer), the transfer of glucose to ceramide. Glucosylceramides play important roles in growth, differentiation and pathogenicity.
messages: Golgi apparatus membrane
messages: Results in complete loss of glucosylceramides (GluCers) in mutant cells (PubMed:11443131). Shows increased resistance to plant defensins MsDef1 and RsAFP2, and to heliomicin, a defensin-like peptide from the insect Heliothis virescens (PubMed:14604982, PubMed:19028992).
messages: The D1, D2, D3, (Q/R)XXRW motif is a critical part of the GCS active site, involved in catalysis and UDP-sugar binding.

644223:PAS chr3 0229
gene id: 644223:PAS_chr3_0229
uniprot id: C4R3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

644223:PAS chr3 0301
gene id: 644223:PAS_chr3_0301
uniprot id: C4R456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

644223:PAS chr1-4 0018
gene id: 644223:PAS_chr1-4_0018
uniprot id: C4QX79
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

644223:PAS chr1-4 0308
gene id: 644223:PAS_chr1-4_0308
uniprot id: C4QY26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr1-4 0081
gene id: 644223:PAS_chr1-4_0081
uniprot id: C4QXD7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

644223:PAS chr1-1 0021
gene id: 644223:PAS_chr1-1_0021
uniprot id: C4QVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

644223:PAS chr1-1 0202
gene id: 644223:PAS_chr1-1_0202
uniprot id: C4QWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

644223:PAS chr2-2 0159
gene id: 644223:PAS_chr2-2_0159
uniprot id: C4R2P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

644223:PAS chr2-1 0206
gene id: 644223:PAS_chr2-1_0206
uniprot id: C4QZZ0
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-3 0094
gene id: 644223:PAS_chr1-3_0094
uniprot id: C4QV80
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

644223:PAS chr1-4 0351
gene id: 644223:PAS_chr1-4_0351
uniprot id: C4QY70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

644223:PAS chr2-1 0279
gene id: 644223:PAS_chr2-1_0279
uniprot id: C4R069
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr2-2 0250
gene id: 644223:PAS_chr2-2_0250
uniprot id: C4R2E0
names: Similarity
messages: Belongs to the SEN54 family.

644223:PAS chr1-3 0241
gene id: 644223:PAS_chr1-3_0241
uniprot id: C4QVN0
names: Similarity
messages: Belongs to the SF3A2 family.

644223:PAS chr1-1 0426
gene id: 644223:PAS_chr1-1_0426
uniprot id: C4QX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

644223:PAS chr1-3 0186
gene id: 644223:PAS_chr1-3_0186
uniprot id: C4QVH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

644223:PAS chr2-1 0487
gene id: 644223:PAS_chr2-1_0487
uniprot id: C4R0U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

644223:PAS chr4 0925
gene id: 644223:PAS_chr4_0925
uniprot id: C4R752
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

644223:PAS chr3 0225
gene id: 644223:PAS_chr3_0225
uniprot id: C4R3X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

644223:PAS chr2-1 0716
gene id: 644223:PAS_chr2-1_0716
uniprot id: C4R1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

644223:PAS chr3 0464
gene id: 644223:PAS_chr3_0464
uniprot id: C4R4M7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0234
gene id: 644223:PAS_chr3_0234
uniprot id: C4R3Y5
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

644223:PAS chr4 0412
gene id: 644223:PAS_chr4_0412
uniprot id: C4R7T6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

644223:PAS chr2-1 0803
gene id: 644223:PAS_chr2-1_0803
uniprot id: C4R1T8
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

644223:PAS chr1-1 0397
gene id: 644223:PAS_chr1-1_0397
uniprot id: C4QX01
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

644223:PAS chr2-1 0277
gene id: 644223:PAS_chr2-1_0277
uniprot id: C4R067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

644223:PAS chr1-4 0275
gene id: 644223:PAS_chr1-4_0275
uniprot id: C4QXY6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

644223:PAS chr2-1 0152
gene id: 644223:PAS_chr2-1_0152
uniprot id: C4QZT5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

644223:PAS chr3 0280
gene id: 644223:PAS_chr3_0280
uniprot id: C4R433
names: Similarity
messages: Belongs to the GET4 family.

644223:PAS chr3 0317
gene id: 644223:PAS_chr3_0317
uniprot id: C4R470
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

644223:PAS chr1-1 0420
gene id: 644223:PAS_chr1-1_0420
uniprot id: C4QX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

644223:PAS chr3 0224
gene id: 644223:PAS_chr3_0224
uniprot id: C4R3X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

644223:PAS chr2-1 0609
gene id: 644223:PAS_chr2-1_0609
uniprot id: C4R172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

644223:PAS chr4 0752
gene id: 644223:PAS_chr4_0752
uniprot id: C4R8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

644223:PAS chr4 0312
gene id: 644223:PAS_chr4_0312
uniprot id: C4R7H8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

644223:PAS chr4 0659
gene id: 644223:PAS_chr4_0659
uniprot id: C4R8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr1-1 0212
gene id: 644223:PAS_chr1-1_0212
uniprot id: C4QWF8
names: Similarity
messages: Belongs to the Fmt family.

644223:PAS chr3 1160
gene id: 644223:PAS_chr3_1160
uniprot id: C4R3S0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0704
gene id: 644223:PAS_chr2-1_0704
uniprot id: C4R1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

644223:PAS chr2-1 0547
gene id: 644223:PAS_chr2-1_0547
uniprot id: C4R107
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

644223:PAS chr1-4 0253
gene id: 644223:PAS_chr1-4_0253
uniprot id: C4QXW4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

644223:PAS chr1-1 0327
gene id: 644223:PAS_chr1-1_0327
uniprot id: C4QWS9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

644223:PAS chr1-4 0649
gene id: 644223:PAS_chr1-4_0649
uniprot id: C4QZ37
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

644223:PAS chr1-4 0328
gene id: 644223:PAS_chr1-4_0328
uniprot id: C4QY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

644223:PAS chr1-1 0391
gene id: 644223:PAS_chr1-1_0391
uniprot id: C4QWZ5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr3 0838
gene id: 644223:PAS_chr3_0838
uniprot id: C4R5Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

644223:PAS chr2-1 0104
gene id: 644223:PAS_chr2-1_0104
uniprot id: C4QZN2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0641
gene id: 644223:PAS_chr2-1_0641
uniprot id: C4R1B1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

644223:PAS chr4 0443
gene id: 644223:PAS_chr4_0443
uniprot id: C4R7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

644223:PAS chr4 0904
gene id: 644223:PAS_chr4_0904
uniprot id: C4R999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

644223:PAS chr2-1 0358
gene id: 644223:PAS_chr2-1_0358
uniprot id: C4R0F4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

644223:PAS chr3 1071
gene id: 644223:PAS_chr3_1071
uniprot id: C4R6E8
names: Similarity
messages: Belongs to the GST superfamily.

644223:PAS chr4 0422
gene id: 644223:PAS_chr4_0422
uniprot id: C4R7U6
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

644223:PAS chr3 0141
gene id: 644223:PAS_chr3_0141
uniprot id: C4R3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr3 1110
gene id: 644223:PAS_chr3_1110
uniprot id: C4R6J1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr4 0578
gene id: 644223:PAS_chr4_0578
uniprot id: C4R8B2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

644223:PAS chr2-2 0372
gene id: 644223:PAS_chr2-2_0372
uniprot id: C4R209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET191 family.
messages: Mitochondrion intermembrane space

644223:PAS chr2-1 0324
gene id: 644223:PAS_chr2-1_0324
uniprot id: C4R0B7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

644223:PAS chr4 0795
gene id: 644223:PAS_chr4_0795
uniprot id: C4R8Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

644223:PAS chr2-2 0297
gene id: 644223:PAS_chr2-2_0297
uniprot id: C4R286
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

644223:PAS chr1-4 0589
gene id: 644223:PAS_chr1-4_0589
uniprot id: C4QYX3
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

644223:PAS chr4 0519
gene id: 644223:PAS_chr4_0519
uniprot id: C4R849
names: Similarity
messages: Belongs to the HGH1 family.

644223:PAS chr4 0801
gene id: 644223:PAS_chr4_0801
uniprot id: C4R8Z6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0382
gene id: 644223:PAS_chr4_0382
uniprot id: C4R7Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EXO5 family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Mitochondrion
messages: Monomer.
messages: Single strand DNA specific 5'exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).

644223:PAS chr2-2 0344
gene id: 644223:PAS_chr2-2_0344
uniprot id: C4R238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0005
gene id: 644223:PAS_chr1-1_0005
uniprot id: C4QVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytoskeleton

644223:PAS chr1-4 0482
gene id: 644223:PAS_chr1-4_0482
uniprot id: C4QYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

644223:PAS chr2-2 0137
gene id: 644223:PAS_chr2-2_0137
uniprot id: C4R2R4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

644223:PAS chr4 0733
gene id: 644223:PAS_chr4_0733
uniprot id: C4R8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0636
gene id: 644223:PAS_chr1-4_0636
uniprot id: C4QZ23
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0155
gene id: 644223:PAS_chr4_0155
uniprot id: C4R705
names: Similarity
messages: Belongs to the OPA3 family.

644223:PAS chr1-1 0069
gene id: 644223:PAS_chr1-1_0069
uniprot id: C4QW05
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0218
gene id: 644223:PAS_chr3_0218
uniprot id: C4R3W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr2-1 0058
gene id: 644223:PAS_chr2-1_0058
uniprot id: C4QZI5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr4 0353
gene id: 644223:PAS_chr4_0353
uniprot id: C4R7M2
names: Similarity
messages: Belongs to the HscB family.

644223:PAS chr2-1 0428
gene id: 644223:PAS_chr2-1_0428
uniprot id: C4R0M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

644223:PAS chr4 0930
gene id: 644223:PAS_chr4_0930
uniprot id: C4R782
names: Similarity
messages: Belongs to the NOC2 family.

644223:PAS chr1-4 0022
gene id: 644223:PAS_chr1-4_0022
uniprot id: C4QX83
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

644223:PAS chr4 0196
gene id: 644223:PAS_chr4_0196
uniprot id: C4R747
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

644223:PAS chr1-4 0658
gene id: 644223:PAS_chr1-4_0658
uniprot id: C4QXM5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0866
gene id: 644223:PAS_chr3_0866
uniprot id: C4R5T4
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr2-2 0027
gene id: 644223:PAS_chr2-2_0027
uniprot id: C4R337
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr4 0212
gene id: 644223:PAS_chr4_0212
uniprot id: C4R763
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

644223:PAS chr3 0841
gene id: 644223:PAS_chr3_0841
uniprot id: C4R5Q6
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

644223:PAS chr1-3 0082
gene id: 644223:PAS_chr1-3_0082
uniprot id: C4QV65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

644223:PAS chr1-4 0441
gene id: 644223:PAS_chr1-4_0441
uniprot id: C4QYG9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

644223:PAS chr4 0777
gene id: 644223:PAS_chr4_0777
uniprot id: C4R8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

644223:PAS chr3 0602
gene id: 644223:PAS_chr3_0602
uniprot id: C4R513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

644223:PAS chr3 0160
gene id: 644223:PAS_chr3_0160
uniprot id: C4R3Q1
names: Similarity
messages: Belongs to the BRX1 family.

644223:PAS chr2-1 0850
gene id: 644223:PAS_chr2-1_0850
uniprot id: C4R0S5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

644223:PAS chr2-2 0019
gene id: 644223:PAS_chr2-2_0019
uniprot id: C4R343
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr1-1 0445
gene id: 644223:PAS_chr1-1_0445
uniprot id: C4QX49
names: Similarity
messages: Belongs to the UPF0045 family.

644223:PAS chr3 0638
gene id: 644223:PAS_chr3_0638
uniprot id: C4R551
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0176
gene id: 644223:PAS_chr3_0176
uniprot id: C4R3R8
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS chr4 0223
gene id: 644223:PAS_chr4_0223
uniprot id: C4R776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

644223:PAS chr2-2 0036
gene id: 644223:PAS_chr2-2_0036
uniprot id: C4R326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0325
gene id: 644223:PAS_chr1-4_0325
uniprot id: C4QY43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr1-1 0119
gene id: 644223:PAS_chr1-1_0119
uniprot id: C4QW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

644223:PAS chr3 0264
gene id: 644223:PAS_chr3_0264
uniprot id: C4R416
names: Similarity
messages: Belongs to the ferrochelatase family.

644223:PAS chr4 0129
gene id: 644223:PAS_chr4_0129
uniprot id: C4R6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

644223:PAS chr4 0506
gene id: 644223:PAS_chr4_0506
uniprot id: C4R837
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr2-2 0230
gene id: 644223:PAS_chr2-2_0230
uniprot id: C4R2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0199
gene id: 644223:PAS_chr2-1_0199
uniprot id: C4QZY3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

644223:PAS chr3 1240
gene id: 644223:PAS_chr3_1240
uniprot id: C4R601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

644223:PAS chr3 0432
gene id: 644223:PAS_chr3_0432
uniprot id: C4R4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

644223:PAS chr1-4 0619
gene id: 644223:PAS_chr1-4_0619
uniprot id: C4QZ04
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0593
gene id: 644223:PAS_chr2-1_0593
uniprot id: C4R156
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

644223:PAS chr2-1 0730
gene id: 644223:PAS_chr2-1_0730
uniprot id: C4R1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

644223:PAS chr2-2 0093
gene id: 644223:PAS_chr2-2_0093
uniprot id: C4R2W1
names: Similarity
messages: Belongs to the MYG1 family.

644223:PAS chr3 0575
gene id: 644223:PAS_chr3_0575
uniprot id: C4R4Y7
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr4 0502
gene id: 644223:PAS_chr4_0502
uniprot id: C4R833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

644223:PAS chr3 0742
gene id: 644223:PAS_chr3_0742
uniprot id: C4R5F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

644223:PAS chr4 0705
gene id: 644223:PAS_chr4_0705
uniprot id: C4R8P2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS c131 0003
gene id: 644223:PAS_c131_0003
uniprot id: C4R381
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

644223:PAS chr1-4 0048
gene id: 644223:PAS_chr1-4_0048
uniprot id: C4QXA6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0118
gene id: 644223:PAS_chr1-4_0118
uniprot id: C4QXH4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0547
gene id: 644223:PAS_chr1-4_0547
uniprot id: C4QYS9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

644223:PAS chr1-4 0634
gene id: 644223:PAS_chr1-4_0634
uniprot id: C4QZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

644223:PAS chr4 0121
gene id: 644223:PAS_chr4_0121
uniprot id: C4R6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

644223:PAS chr2-1 0426
gene id: 644223:PAS_chr2-1_0426
uniprot id: C4R0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRC22 family.
messages: Endoplasmic reticulum membrane
messages: Is probably involved in a pathway contributing to genomic integrity.

644223:PAS chr1-4 0110
gene id: 644223:PAS_chr1-4_0110
uniprot id: C4QXG6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

644223:PAS chr3 0108
gene id: 644223:PAS_chr3_0108
uniprot id: C4R3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

644223:PAS chr2-1 0449
gene id: 644223:PAS_chr2-1_0449
uniprot id: C4R0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

644223:PAS chr1-3 0075
gene id: 644223:PAS_chr1-3_0075
uniprot id: C4QV57
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

644223:PAS chr4 0686
gene id: 644223:PAS_chr4_0686
uniprot id: C4R8M0
names: Similarity
messages: Belongs to the peptidase M20A family.

644223:PAS chr1-4 0524
gene id: 644223:PAS_chr1-4_0524
uniprot id: C4QYQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

644223:PAS chr4 0786
gene id: 644223:PAS_chr4_0786
uniprot id: C4R8X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

644223:PAS chr3 0197
gene id: 644223:PAS_chr3_0197
uniprot id: C4R3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

644223:PAS chr2-1 0457
gene id: 644223:PAS_chr2-1_0457
uniprot id: C4R0R0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0247
gene id: 644223:PAS_chr2-2_0247
uniprot id: C4R2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

644223:PAS chr4 0754
gene id: 644223:PAS_chr4_0754
uniprot id: C4R8U1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr4 0541
gene id: 644223:PAS_chr4_0541
uniprot id: C4R876
names: Similarity
messages: Belongs to the SAPS family.

644223:PAS chr2-1 0404
gene id: 644223:PAS_chr2-1_0404
uniprot id: C4R0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

644223:PAS chr1-4 0645
gene id: 644223:PAS_chr1-4_0645
uniprot id: C4QZ33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

644223:PAS chr1-4 0245
gene id: 644223:PAS_chr1-4_0245
uniprot id: C4QXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.
messages: Nucleus

644223:PAS chr2-1 0112
gene id: 644223:PAS_chr2-1_0112
uniprot id: C4QZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

644223:PAS chr2-2 0495
gene id: 644223:PAS_chr2-2_0495
uniprot id: C4R1Y2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

644223:PAS chr3 0243
gene id: 644223:PAS_chr3_0243
uniprot id: C4R3Z4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

644223:PAS chr3 0977
gene id: 644223:PAS_chr3_0977
uniprot id: C4R655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr1-4 0609
gene id: 644223:PAS_chr1-4_0609
uniprot id: C4QYZ4
names: Similarity
messages: Belongs to the cullin family.

644223:PAS chr2-1 0635
gene id: 644223:PAS_chr2-1_0635
uniprot id: C4R1A4
names: Similarity
messages: Belongs to the PPP phosphatase family.

644223:PAS chr2-2 0196
gene id: 644223:PAS_chr2-2_0196
uniprot id: C4R2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

644223:PAS chr3 0019
gene id: 644223:PAS_chr3_0019
uniprot id: C4R3B4
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr1-3 0027
gene id: 644223:PAS_chr1-3_0027
uniprot id: C4QV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

644223:PAS chr1-1 0247
gene id: 644223:PAS_chr1-1_0247
uniprot id: C4QWJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

644223:PAS chr2-1 0828
gene id: 644223:PAS_chr2-1_0828
uniprot id: C4R0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

644223:PAS chr2-2 0105
gene id: 644223:PAS_chr2-2_0105
uniprot id: C4R2U8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr2-1 0518
gene id: 644223:PAS_chr2-1_0518
uniprot id: C4R0X7
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr1-4 0179
gene id: 644223:PAS_chr1-4_0179
uniprot id: C4QXP0
names: Similarity
messages: Belongs to the TOP6A family.

644223:PAS chr3 0392
gene id: 644223:PAS_chr3_0392
uniprot id: C4R4F3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0501
gene id: 644223:PAS_chr2-1_0501
uniprot id: C4R0V8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0303
gene id: 644223:PAS_chr1-1_0303
uniprot id: C4QWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

644223:PAS chr1-1 0123
gene id: 644223:PAS_chr1-1_0123
uniprot id: C4QW62
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0065
gene id: 644223:PAS_chr3_0065
uniprot id: C4R3F9
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-4 0072
gene id: 644223:PAS_chr1-4_0072
uniprot id: C4QXC8
names: Similarity
messages: Belongs to the AHA1 family.

644223:PAS chr4 0856
gene id: 644223:PAS_chr4_0856
uniprot id: C4R950
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

644223:PAS chr3 0037
gene id: 644223:PAS_chr3_0037
uniprot id: C4R3C8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

644223:PAS chr1-4 0491
gene id: 644223:PAS_chr1-4_0491
uniprot id: C4QYM1
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

644223:PAS chr1-1 0117
gene id: 644223:PAS_chr1-1_0117
uniprot id: C4QW55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr3 0434
gene id: 644223:PAS_chr3_0434
uniprot id: C4R4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0530
gene id: 644223:PAS_chr4_0530
uniprot id: C4R864
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

644223:PAS chr4 0695
gene id: 644223:PAS_chr4_0695
uniprot id: C4R8N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

644223:PAS chr2-1 0617
gene id: 644223:PAS_chr2-1_0617
uniprot id: C4R183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

644223:PAS chr3 0089
gene id: 644223:PAS_chr3_0089
uniprot id: C4R3I4
names: Similarity
messages: Belongs to the AIM6 family.

644223:PAS chr3 0156
gene id: 644223:PAS_chr3_0156
uniprot id: C4R3P7
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

644223:PAS chr4 0246
gene id: 644223:PAS_chr4_0246
uniprot id: C4R7A1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

644223:PAS chr1-1 0098
gene id: 644223:PAS_chr1-1_0098
uniprot id: C4QW37
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

644223:PAS chr3 0162
gene id: 644223:PAS_chr3_0162
uniprot id: C4R3Q3
names: Similarity
messages: Belongs to the SIN1 family.

644223:PAS chr4 0999
gene id: 644223:PAS_chr4_0999
uniprot id: C4R949
names: Similarity
messages: Belongs to the MAPRE family.

644223:PAS chr1-4 0692
gene id: 644223:PAS_chr1-4_0692
uniprot id: C4QYX6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

644223:PAS chr2-1 0154
gene id: 644223:PAS_chr2-1_0154
uniprot id: C4QZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

644223:PAS chr2-2 0476
gene id: 644223:PAS_chr2-2_0476
uniprot id: C4R2G3
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

644223:PAS chr3 1146
gene id: 644223:PAS_chr3_1146
uniprot id: C4R3D5
names: Similarity
messages: Belongs to the VPS29 family.

644223:PAS chr1-4 0585
gene id: 644223:PAS_chr1-4_0585
uniprot id: C4QYW8
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr1-1 0193
gene id: 644223:PAS_chr1-1_0193
uniprot id: C4QWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EST3 family.
messages: Component of the telomerase complex involved in telomere replication. Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase.
messages: Nucleus
messages: telomere

644223:PAS chr1-4 0479
gene id: 644223:PAS_chr1-4_0479
uniprot id: C4QYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

644223:PAS chr3 0808
gene id: 644223:PAS_chr3_0808
uniprot id: C4R5M5
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

644223:PAS chr3 0762
gene id: 644223:PAS_chr3_0762
uniprot id: C4R5H6
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

644223:PAS chr2-2 0220
gene id: 644223:PAS_chr2-2_0220
uniprot id: C4R2H3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

644223:PAS chr3 0667
gene id: 644223:PAS_chr3_0667
uniprot id: C4R578
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

644223:PAS chr2-1 0236
gene id: 644223:PAS_chr2-1_0236
uniprot id: C4R022
names: Similarity
messages: Belongs to the sulfiredoxin family.

644223:PAS chr1-1 0216
gene id: 644223:PAS_chr1-1_0216
uniprot id: C4QWG3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

644223:PAS chr2-1 0069
gene id: 644223:PAS_chr2-1_0069
uniprot id: C4QZJ6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

644223:PAS chr1-1 0011
gene id: 644223:PAS_chr1-1_0011
uniprot id: C4QVU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

644223:PAS chr2-1 0453
gene id: 644223:PAS_chr2-1_0453
uniprot id: C4R0Q6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr1-4 0676
gene id: 644223:PAS_chr1-4_0676
uniprot id: C4QYB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-2 0013
gene id: 644223:PAS_chr2-2_0013
uniprot id: C4R350
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1225
gene id: 644223:PAS_chr3_1225
uniprot id: C4R5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCM1 family.
messages: Mitochondrion
messages: RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts. Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).

644223:PAS chr4 0321
gene id: 644223:PAS_chr4_0321
uniprot id: C4R7I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

644223:PAS chr1-1 0043
gene id: 644223:PAS_chr1-1_0043
uniprot id: C4QVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

644223:PAS chr3 0532
gene id: 644223:PAS_chr3_0532
uniprot id: C4R4U5
names: Similarity
messages: Belongs to the sorting nexin family.

644223:PAS chr1-1 0374
gene id: 644223:PAS_chr1-1_0374
uniprot id: C4QWX8
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

644223:PAS chr1-4 0347
gene id: 644223:PAS_chr1-4_0347
uniprot id: C4QY66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr2-2 0468
gene id: 644223:PAS_chr2-2_0468
uniprot id: C4R2M5
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr4 0120
gene id: 644223:PAS_chr4_0120
uniprot id: C4R6X2
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

644223:PAS chr1-1 0066
gene id: 644223:PAS_chr1-1_0066
uniprot id: C4QW02
names: Similarity
messages: Belongs to the peptidase M24B family.

644223:PAS chr2-1 0066
gene id: 644223:PAS_chr2-1_0066
uniprot id: C4QZJ3
names: Similarity
messages: Belongs to the MON2 family.

644223:PAS chr2-2 0441
gene id: 644223:PAS_chr2-2_0441
uniprot id: C4R1U4
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

644223:PAS chr2-1 0043
gene id: 644223:PAS_chr2-1_0043
uniprot id: C4QZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

644223:PAS chr1-4 0381
gene id: 644223:PAS_chr1-4_0381
uniprot id: C4QYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-3 0229
gene id: 644223:PAS_chr1-3_0229
uniprot id: C4QVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

644223:PAS chr2-1 0442
gene id: 644223:PAS_chr2-1_0442
uniprot id: C4R0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

644223:PAS chr1-4 0144
gene id: 644223:PAS_chr1-4_0144
uniprot id: C4QXJ9
names: Similarity
messages: Belongs to the pyridoxine kinase family.

644223:PAS chr3 0147
gene id: 644223:PAS_chr3_0147
uniprot id: C4R3P0
names: Similarity
messages: Belongs to the TEL2 family.

644223:PAS chr1-1 0255
gene id: 644223:PAS_chr1-1_0255
uniprot id: C4QWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

644223:PAS chr3 1165
gene id: 644223:PAS_chr3_1165
uniprot id: C4R3X0
names: Similarity
messages: Belongs to the SNF8 family.

644223:PAS chr1-4 0393
gene id: 644223:PAS_chr1-4_0393
uniprot id: C4QYB4
names: Similarity
messages: Belongs to the PdxS/SNZ family.

644223:PAS chr2-1 0512
gene id: 644223:PAS_chr2-1_0512
uniprot id: C4R0X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

644223:PAS chr1-3 0213
gene id: 644223:PAS_chr1-3_0213
uniprot id: C4QVK4
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr2-1 0621
gene id: 644223:PAS_chr2-1_0621
uniprot id: C4R187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

644223:PAS chr3 0703
gene id: 644223:PAS_chr3_0703
uniprot id: C4R5B8
names: Subcellular Location Annotation
messages: Mitochondrion

644223:PAS chr1-4 0607
gene id: 644223:PAS_chr1-4_0607
uniprot id: C4QYZ2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0234
gene id: 644223:PAS_chr2-2_0234
uniprot id: C4R2F8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

644223:PAS chr2-2 0293
gene id: 644223:PAS_chr2-2_0293
uniprot id: C4R291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0367
gene id: 644223:PAS_chr2-1_0367
uniprot id: C4R0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

644223:PAS chr4 0170
gene id: 644223:PAS_chr4_0170
uniprot id: C4R720
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0341
gene id: 644223:PAS_chr1-4_0341
uniprot id: C4QY61
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr4 0865
gene id: 644223:PAS_chr4_0865
uniprot id: C4R960
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

644223:PAS chr2-1 0536
gene id: 644223:PAS_chr2-1_0536
uniprot id: C4R0Z5
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

644223:PAS chr4 0867
gene id: 644223:PAS_chr4_0867
uniprot id: C4R962
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

644223:PAS chr3 0599
gene id: 644223:PAS_chr3_0599
uniprot id: C4R510
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

644223:PAS chr4 0716
gene id: 644223:PAS_chr4_0716
uniprot id: C4R8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

644223:PAS chr4 0421
gene id: 644223:PAS_chr4_0421
uniprot id: C4R7U5
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

644223:PAS chr2-1 0648
gene id: 644223:PAS_chr2-1_0648
uniprot id: C4R1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

644223:PAS chr1-4 0054
gene id: 644223:PAS_chr1-4_0054
uniprot id: C4QXB2
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr2-2 0376
gene id: 644223:PAS_chr2-2_0376
uniprot id: C4R205
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

644223:PAS chr4 0484
gene id: 644223:PAS_chr4_0484
uniprot id: C4R816
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr3 0573
gene id: 644223:PAS_chr3_0573
uniprot id: C4R4Y5
names: Similarity
messages: Belongs to the SAS10 family.

644223:PAS chr2-2 0382
gene id: 644223:PAS_chr2-2_0382
uniprot id: C4R1Z9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

644223:PAS chr1-3 0107
gene id: 644223:PAS_chr1-3_0107
uniprot id: C4QV94
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

644223:PAS chr2-2 0149
gene id: 644223:PAS_chr2-2_0149
uniprot id: C4R2Q3
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

644223:PAS chr2-1 0305
gene id: 644223:PAS_chr2-1_0305
uniprot id: C4R096
names: Similarity
messages: Belongs to the NARF family.

644223:PAS chr3 0755
gene id: 644223:PAS_chr3_0755
uniprot id: C4R5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Nucleus

644223:PAS c131 0021
gene id: 644223:PAS_c131_0021
uniprot id: C4R396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

644223:PAS chr2-1 0849
gene id: 644223:PAS_chr2-1_0849
uniprot id: C4R0S3
names: Similarity
messages: Belongs to the TTC4 family.

644223:PAS chr1-4 0593
gene id: 644223:PAS_chr1-4_0593
uniprot id: C4QYX8
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

644223:PAS chr2-1 0030
gene id: 644223:PAS_chr2-1_0030
uniprot id: C4QZF6
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr2-2 0025
gene id: 644223:PAS_chr2-2_0025
uniprot id: C4R338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

644223:PAS chr2-1 0297
gene id: 644223:PAS_chr2-1_0297
uniprot id: C4R087
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

644223:PAS chr3 0944
gene id: 644223:PAS_chr3_0944
uniprot id: C4R619
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Membrane
messages: Nucleus membrane

644223:PAS chr1-4 0575
gene id: 644223:PAS_chr1-4_0575
uniprot id: C4QYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0448
gene id: 644223:PAS_chr4_0448
uniprot id: C4R7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

644223:PAS chr2-1 0072
gene id: 644223:PAS_chr2-1_0072
uniprot id: C4QZJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

644223:PAS chr1-3 0031
gene id: 644223:PAS_chr1-3_0031
uniprot id: C4QV13
names: Similarity
messages: Belongs to the VPS52 family.

644223:PAS chr1-4 0412
gene id: 644223:PAS_chr1-4_0412
uniprot id: C4QYD7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

644223:PAS chr1-1 0345
gene id: 644223:PAS_chr1-1_0345
uniprot id: C4QWU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

644223:PAS chr1-1 0384
gene id: 644223:PAS_chr1-1_0384
uniprot id: C4QWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM36 family.
messages: Mitochondrion membrane

644223:PAS chr2-1 0702
gene id: 644223:PAS_chr2-1_0702
uniprot id: C4R1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

644223:PAS chr4 0239
gene id: 644223:PAS_chr4_0239
uniprot id: C4R793
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

644223:PAS chr2-1 0872
gene id: 644223:PAS_chr2-1_0872
uniprot id: C4R197
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

644223:PAS chr2-1 0042
gene id: 644223:PAS_chr2-1_0042
uniprot id: C4QZG8
names: Similarity
messages: Belongs to the FES1 family.

644223:PAS chr4 0178
gene id: 644223:PAS_chr4_0178
uniprot id: C4R729
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

644223:PAS chr2-1 0408
gene id: 644223:PAS_chr2-1_0408
uniprot id: C4R0K5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0342
gene id: 644223:PAS_chr3_0342
uniprot id: C4R495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

644223:PAS chr1-1 0354
gene id: 644223:PAS_chr1-1_0354
uniprot id: C4QWV7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0079
gene id: 644223:PAS_chr4_0079
uniprot id: C4R6T0
names: Similarity
messages: Belongs to the ATG16 family.

644223:PAS chr3 0629
gene id: 644223:PAS_chr3_0629
uniprot id: C4R541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
messages: Nucleus

644223:PAS chr4 0101
gene id: 644223:PAS_chr4_0101
uniprot id: C4R6V2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

644223:PAS chr1-1 0398
gene id: 644223:PAS_chr1-1_0398
uniprot id: C4QX02
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0403
gene id: 644223:PAS_chr1-4_0403
uniprot id: C4QYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

644223:PAS chr1-3 0097
gene id: 644223:PAS_chr1-3_0097
uniprot id: C4QV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0527
gene id: 644223:PAS_chr1-4_0527
uniprot id: C4QYQ6
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

644223:PAS chr1-4 0496
gene id: 644223:PAS_chr1-4_0496
uniprot id: C4QYM5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

644223:PAS chr4 0449
gene id: 644223:PAS_chr4_0449
uniprot id: C4R7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

644223:PAS chr2-1 0865
gene id: 644223:PAS_chr2-1_0865
uniprot id: C4R151
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr4 0021
gene id: 644223:PAS_chr4_0021
uniprot id: C4R6M2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

644223:PAS chr1-1 0385
gene id: 644223:PAS_chr1-1_0385
uniprot id: C4QWY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

644223:PAS chr4 0917
gene id: 644223:PAS_chr4_0917
uniprot id: C4R6S4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0691
gene id: 644223:PAS_chr4_0691
uniprot id: C4R8M7
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

644223:PAS chr3 0998
gene id: 644223:PAS_chr3_0998
uniprot id: C4R674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

644223:PAS chr1-3 0156
gene id: 644223:PAS_chr1-3_0156
uniprot id: C4QVE4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

644223:PAS chr4 0278
gene id: 644223:PAS_chr4_0278
uniprot id: C4R7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

644223:PAS chr4 0615
gene id: 644223:PAS_chr4_0615
uniprot id: C4R8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

644223:PAS chr1-4 0295
gene id: 644223:PAS_chr1-4_0295
uniprot id: C4QY10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

644223:PAS chr2-1 0026
gene id: 644223:PAS_chr2-1_0026
uniprot id: C4QZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

644223:PAS chr4 0714
gene id: 644223:PAS_chr4_0714
uniprot id: C4R8Q0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0409
gene id: 644223:PAS_chr1-1_0409
uniprot id: C4QX13
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr2-1 0437
gene id: 644223:PAS_chr2-1_0437
uniprot id: C4R0P1
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

644223:PAS chr3 0165
gene id: 644223:PAS_chr3_0165
uniprot id: C4R3Q5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr2-1 0232
gene id: 644223:PAS_chr2-1_0232
uniprot id: C4R018
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0195
gene id: 644223:PAS_chr2-1_0195
uniprot id: C4QZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

644223:PAS c121 0012
gene id: 644223:PAS_c121_0012
uniprot id: C4QZ51
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

644223:PAS chr2-2 0367
gene id: 644223:PAS_chr2-2_0367
uniprot id: C4R214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

644223:PAS chr1-1 0007
gene id: 644223:PAS_chr1-1_0007
uniprot id: C4QVT7
names: Similarity
messages: Belongs to the SRR1 family.

644223:PAS chr4 0355
gene id: 644223:PAS_chr4_0355
uniprot id: C4R7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0210
gene id: 644223:PAS_chr4_0210
uniprot id: C4R760
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

644223:PAS chr1-3 0091
gene id: 644223:PAS_chr1-3_0091
uniprot id: C4QV75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

644223:PAS chr1-4 0471
gene id: 644223:PAS_chr1-4_0471
uniprot id: C4QYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

644223:PAS chr2-1 0165
gene id: 644223:PAS_chr2-1_0165
uniprot id: C4QZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

644223:PAS chr2-1 0709
gene id: 644223:PAS_chr2-1_0709
uniprot id: C4R1I3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

644223:PAS chr2-1 0473
gene id: 644223:PAS_chr2-1_0473
uniprot id: C4R0S9
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

644223:PAS chr1-4 0472
gene id: 644223:PAS_chr1-4_0472
uniprot id: C4QYK1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0085
gene id: 644223:PAS_chr3_0085
uniprot id: C4R3I1
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

644223:PAS chr3 0232
gene id: 644223:PAS_chr3_0232
uniprot id: C4R3Y3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0284
gene id: 644223:PAS_chr2-1_0284
uniprot id: C4R074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0474
gene id: 644223:PAS_chr2-1_0474
uniprot id: C4R0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 22 family.
messages: Nucleus

644223:PAS chr1-1 0430
gene id: 644223:PAS_chr1-1_0430
uniprot id: C4QX34
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

644223:PAS chr1-1 0411
gene id: 644223:PAS_chr1-1_0411
uniprot id: C4QX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

644223:PAS chr4 0043
gene id: 644223:PAS_chr4_0043
uniprot id: C4R6P6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr3 1164
gene id: 644223:PAS_chr3_1164
uniprot id: C4R3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

644223:PAS chr2-1 0714
gene id: 644223:PAS_chr2-1_0714
uniprot id: C4R1I9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr1-4 0506
gene id: 644223:PAS_chr1-4_0506
uniprot id: C4QYN5
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr2-2 0265
gene id: 644223:PAS_chr2-2_0265
uniprot id: C4R2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0303
gene id: 644223:PAS_chr2-1_0303
uniprot id: C4R094
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

644223:PAS chr2-1 0221
gene id: 644223:PAS_chr2-1_0221
uniprot id: C4R007
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

644223:PAS chr4 0153
gene id: 644223:PAS_chr4_0153
uniprot id: C4R703
names: Similarity
messages: Belongs to the lysophospholipase family.

644223:PAS chr3 1158
gene id: 644223:PAS_chr3_1158
uniprot id: C4R3R1
names: Similarity
messages: Belongs to the VPS72/YL1 family.

644223:PAS chr3 0520
gene id: 644223:PAS_chr3_0520
uniprot id: C4R4T3
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

644223:PAS chr4 0261
gene id: 644223:PAS_chr4_0261
uniprot id: C4R7C0
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

644223:PAS chr3 0646
gene id: 644223:PAS_chr3_0646
uniprot id: C4R558
names: Similarity
messages: Belongs to the phospholipase D family.

644223:PAS chr3 1157
gene id: 644223:PAS_chr3_1157
uniprot id: C4R3Q7
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr1-3 0206
gene id: 644223:PAS_chr1-3_0206
uniprot id: C4QVJ7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0073
gene id: 644223:PAS_chr2-2_0073
uniprot id: C4R2Y5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0562
gene id: 644223:PAS_chr3_0562
uniprot id: C4R4X4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

644223:PAS chr1-1 0498
gene id: 644223:PAS_chr1-1_0498
uniprot id: C4QWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

644223:PAS chr1-4 0683
gene id: 644223:PAS_chr1-4_0683
uniprot id: C4QYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0369
gene id: 644223:PAS_chr1-4_0369
uniprot id: C4QY89
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

644223:PAS chr3 0181
gene id: 644223:PAS_chr3_0181
uniprot id: C4R3S5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

644223:PAS chr3 0421
gene id: 644223:PAS_chr3_0421
uniprot id: C4R4I4
names: Similarity
messages: Belongs to the OSBP family.

644223:PAS chr1-1 0490
gene id: 644223:PAS_chr1-1_0490
uniprot id: C4QWM9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr4 0661
gene id: 644223:PAS_chr4_0661
uniprot id: C4R8J4
names: Similarity
messages: Belongs to the MAK16 family.

644223:PAS chr2-1 0773
gene id: 644223:PAS_chr2-1_0773
uniprot id: C4R1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

644223:PAS chr1-3 0071
gene id: 644223:PAS_chr1-3_0071
uniprot id: C4QV53
names: Subcellular Location Annotation
messages: nuclear pore complex

644223:PAS chr1-3 0185
gene id: 644223:PAS_chr1-3_0185
uniprot id: C4QVH5
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

644223:PAS chr2-2 0432
gene id: 644223:PAS_chr2-2_0432
uniprot id: C4R1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

644223:PAS chr4 0671
gene id: 644223:PAS_chr4_0671
uniprot id: C4R8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0926
gene id: 644223:PAS_chr3_0926
uniprot id: C4R5Z8
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr3 0664
gene id: 644223:PAS_chr3_0664
uniprot id: C4R575
names: Subcellular Location Annotation
messages: Mitochondrion

644223:PAS chr2-2 0075
gene id: 644223:PAS_chr2-2_0075
uniprot id: C4R2Y2
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

644223:PAS chr1-1 0029
gene id: 644223:PAS_chr1-1_0029
uniprot id: C4QVW0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

644223:PAS chr3 0546
gene id: 644223:PAS_chr3_0546
uniprot id: C4R4V8
names: Similarity
names: Subunit
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.

644223:PAS chr3 0329
gene id: 644223:PAS_chr3_0329
uniprot id: C4R481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

644223:PAS chr3 1127
gene id: 644223:PAS_chr3_1127
uniprot id: C4R360
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: The C2 domains have an essential, but non-catalytic function. They may facilitate interaction with PstB2 and are required for lipid transport function.

644223:PAS chr1-3 0115
gene id: 644223:PAS_chr1-3_0115
uniprot id: C4QVA2
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

644223:PAS chr3 0858
gene id: 644223:PAS_chr3_0858
uniprot id: C4R5S6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0317
gene id: 644223:PAS_chr2-2_0317
uniprot id: C4R265
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

644223:PAS chr4 0832
gene id: 644223:PAS_chr4_0832
uniprot id: C4R926
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0074
gene id: 644223:PAS_chr3_0074
uniprot id: C4R3H0
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

644223:PAS chr2-2 0267
gene id: 644223:PAS_chr2-2_0267
uniprot id: C4R2C2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

644223:PAS chr4 0736
gene id: 644223:PAS_chr4_0736
uniprot id: C4R8S3
names: Similarity
messages: Belongs to the AAA ATPase family.

644223:PAS chr3 0018
gene id: 644223:PAS_chr3_0018
uniprot id: C4R3B3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0765
gene id: 644223:PAS_chr2-1_0765
uniprot id: C4R1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

644223:PAS chr1-4 0559
gene id: 644223:PAS_chr1-4_0559
uniprot id: C4QYU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

644223:PAS chr1-4 0212
gene id: 644223:PAS_chr1-4_0212
uniprot id: C4QXS5
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

644223:PAS chr2-2 0316
gene id: 644223:PAS_chr2-2_0316
uniprot id: C4R266
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

644223:PAS chr3 0939
gene id: 644223:PAS_chr3_0939
uniprot id: C4R613
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides. Required for the formation of the monounsaturated sphingoid base (E)-sphing-4-enine during glucosylceramide (GluCer) biosynthesis.
messages: Membrane

644223:PAS chr4 1001
gene id: 644223:PAS_chr4_1001
uniprot id: C4R974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

644223:PAS chr3 1201
gene id: 644223:PAS_chr3_1201
uniprot id: C4R524
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0041
gene id: 644223:PAS_chr4_0041
uniprot id: C4R6P3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

644223:PAS chr4 0908
gene id: 644223:PAS_chr4_0908
uniprot id: C4R9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

644223:PAS chr4 0613
gene id: 644223:PAS_chr4_0613
uniprot id: C4R8E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

644223:PAS chr1-3 0128
gene id: 644223:PAS_chr1-3_0128
uniprot id: C4QVB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

644223:PAS chr2-1 0422
gene id: 644223:PAS_chr2-1_0422
uniprot id: C4R0M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr3 1028
gene id: 644223:PAS_chr3_1028
uniprot id: C4R6A5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

644223:PAS chr2-2 0445
gene id: 644223:PAS_chr2-2_0445
uniprot id: C4R1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

644223:PAS chr1-4 0483
gene id: 644223:PAS_chr1-4_0483
uniprot id: C4QYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

644223:PAS chr3 0040
gene id: 644223:PAS_chr3_0040
uniprot id: C4R3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0222
gene id: 644223:PAS_chr3_0222
uniprot id: C4R3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0269
gene id: 644223:PAS_chr1-4_0269
uniprot id: C4QXY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

644223:PAS chr1-4 0678
gene id: 644223:PAS_chr1-4_0678
uniprot id: C4QYC5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

644223:PAS chr2-1 0418
gene id: 644223:PAS_chr2-1_0418
uniprot id: C4R0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

644223:PAS chr4 0535
gene id: 644223:PAS_chr4_0535
uniprot id: C4R870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

644223:PAS chr2-2 0107
gene id: 644223:PAS_chr2-2_0107
uniprot id: C4R2U6
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

644223:PAS chr1-1 0364
gene id: 644223:PAS_chr1-1_0364
uniprot id: C4QWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

644223:PAS chr1-3 0083
gene id: 644223:PAS_chr1-3_0083
uniprot id: C4QV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

644223:PAS chr3 0603
gene id: 644223:PAS_chr3_0603
uniprot id: C4R514
names: Similarity
messages: Belongs to the RNase PH family.

644223:PAS chr4 0381
gene id: 644223:PAS_chr4_0381
uniprot id: C4R7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM11 family.
messages: Membrane

644223:PAS chr1-1 0318
gene id: 644223:PAS_chr1-1_0318
uniprot id: C4QWS1
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0590
gene id: 644223:PAS_chr3_0590
uniprot id: C4R502
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0651
gene id: 644223:PAS_chr4_0651
uniprot id: C4R8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

644223:PAS chr2-1 0633
gene id: 644223:PAS_chr2-1_0633
uniprot id: C4R1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

644223:PAS chr2-1 0891
gene id: 644223:PAS_chr2-1_0891
uniprot id: C4R1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

644223:PAS chr3 0507
gene id: 644223:PAS_chr3_0507
uniprot id: C4R4R9
names: Similarity
messages: Belongs to the cytochrome P450 family.

644223:PAS chr3 1049
gene id: 644223:PAS_chr3_1049
uniprot id: C4R6C5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0391
gene id: 644223:PAS_chr3_0391
uniprot id: C4R4F2
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

644223:PAS chr2-1 0613
gene id: 644223:PAS_chr2-1_0613
uniprot id: C4R178
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1086
gene id: 644223:PAS_chr3_1086
uniprot id: C4R6G7
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

644223:PAS chr1-3 0026
gene id: 644223:PAS_chr1-3_0026
uniprot id: C4QV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

644223:PAS chr3 1067
gene id: 644223:PAS_chr3_1067
uniprot id: C4R6E3
names: Similarity
messages: Belongs to the RNase PH family.

644223:PAS chr4 0126
gene id: 644223:PAS_chr4_0126
uniprot id: C4R6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

644223:PAS chr1-3 0180
gene id: 644223:PAS_chr1-3_0180
uniprot id: C4QVH0
names: Similarity
messages: Belongs to the EFR3 family.

644223:PAS chr4 0456
gene id: 644223:PAS_chr4_0456
uniprot id: C4R7Y4
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

644223:PAS chr2-2 0207
gene id: 644223:PAS_chr2-2_0207
uniprot id: C4R2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

644223:PAS chr1-1 0012
gene id: 644223:PAS_chr1-1_0012
uniprot id: C4QVU2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0102
gene id: 644223:PAS_chr2-2_0102
uniprot id: C4R2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0063
gene id: 644223:PAS_chr1-1_0063
uniprot id: C4QVZ8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

644223:PAS chr2-2 0431
gene id: 644223:PAS_chr2-2_0431
uniprot id: C4R1V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

644223:PAS chr4 0790
gene id: 644223:PAS_chr4_0790
uniprot id: C4R8Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

644223:PAS chr3 0366
gene id: 644223:PAS_chr3_0366
uniprot id: C4R4C4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

644223:PAS chr1-3 0269
gene id: 644223:PAS_chr1-3_0269
uniprot id: C4QVR0
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

644223:PAS chr1-1 0067
gene id: 644223:PAS_chr1-1_0067
uniprot id: C4QW03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

644223:PAS chr3 1143
gene id: 644223:PAS_chr3_1143
uniprot id: C4R378
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0286
gene id: 644223:PAS_chr4_0286
uniprot id: C4R7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

644223:PAS chr2-2 0460
gene id: 644223:PAS_chr2-2_0460
uniprot id: C4R2W0
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

644223:PAS chr1-3 0096
gene id: 644223:PAS_chr1-3_0096
uniprot id: C4QV82
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

644223:PAS chr2-1 0517
gene id: 644223:PAS_chr2-1_0517
uniprot id: C4R0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

644223:PAS chr2-2 0039
gene id: 644223:PAS_chr2-2_0039
uniprot id: C4R323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

644223:PAS chr3 0506
gene id: 644223:PAS_chr3_0506
uniprot id: C4R4R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: In the 2nd section; belongs to the EPSP synthase family.
messages: In the 3rd section; belongs to the shikimate kinase family.
messages: In the 4th section; belongs to the type-I 3-dehydroquinase family.
messages: In the C-terminal section; belongs to the shikimate dehydrogenase family.
messages: In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.

644223:PAS chr2-1 0806
gene id: 644223:PAS_chr2-1_0806
uniprot id: C4QZF0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0462
gene id: 644223:PAS_chr1-4_0462
uniprot id: C4QYJ1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0255
gene id: 644223:PAS_chr3_0255
uniprot id: C4R406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-1 0809
gene id: 644223:PAS_chr2-1_0809
uniprot id: C4QZN3
names: Similarity
messages: Belongs to the 14-3-3 family.

644223:PAS chr2-1 0622
gene id: 644223:PAS_chr2-1_0622
uniprot id: C4R188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

644223:PAS chr1-1 0200
gene id: 644223:PAS_chr1-1_0200
uniprot id: C4QWE4
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

644223:PAS chr2-1 0658
gene id: 644223:PAS_chr2-1_0658
uniprot id: C4R1C9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

644223:PAS chr4 0816
gene id: 644223:PAS_chr4_0816
uniprot id: C4R912
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

644223:PAS chr1-1 0382
gene id: 644223:PAS_chr1-1_0382
uniprot id: C4QWY6
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

644223:PAS chr3 0054
gene id: 644223:PAS_chr3_0054
uniprot id: C4R3E7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

644223:PAS chr2-1 0794
gene id: 644223:PAS_chr2-1_0794
uniprot id: C4R1S8
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

644223:PAS chr3 0984
gene id: 644223:PAS_chr3_0984
uniprot id: C4R661
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

644223:PAS FragB 0010
gene id: 644223:PAS_FragB_0010
uniprot id: C4QZ67
names: Similarity
messages: Belongs to the BolA/IbaG family.

644223:PAS chr4 0798
gene id: 644223:PAS_chr4_0798
uniprot id: C4R8Z2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

644223:PAS chr1-4 0664
gene id: 644223:PAS_chr1-4_0664
uniprot id: C4QXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

644223:PAS chr3 0368
gene id: 644223:PAS_chr3_0368
uniprot id: C4R4C6
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

644223:PAS chr3 0819
gene id: 644223:PAS_chr3_0819
uniprot id: C4R5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

644223:PAS chr1-4 0448
gene id: 644223:PAS_chr1-4_0448
uniprot id: C4QYH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

644223:PAS chr2-2 0487
gene id: 644223:PAS_chr2-2_0487
uniprot id: C4R2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

644223:PAS chr1-4 0272
gene id: 644223:PAS_chr1-4_0272
uniprot id: C4QXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

644223:PAS chr2-2 0063
gene id: 644223:PAS_chr2-2_0063
uniprot id: C4R2Z6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr4 0006
gene id: 644223:PAS_chr4_0006
uniprot id: C4R6L0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

644223:PAS chr1-1 0040
gene id: 644223:PAS_chr1-1_0040
uniprot id: C4QVX5
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr1-1 0266
gene id: 644223:PAS_chr1-1_0266
uniprot id: C4QWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

644223:PAS chr3 1111
gene id: 644223:PAS_chr3_1111
uniprot id: C4R6J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

644223:PAS chr4 0159
gene id: 644223:PAS_chr4_0159
uniprot id: C4R709
names: Similarity
messages: Belongs to the NPR2 family.

644223:PAS FragB 0048
gene id: 644223:PAS_FragB_0048
uniprot id: C4QZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

644223:PAS chr3 0152
gene id: 644223:PAS_chr3_0152
uniprot id: C4R3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr1-3 0043
gene id: 644223:PAS_chr1-3_0043
uniprot id: C4QV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

644223:PAS chr3 0647
gene id: 644223:PAS_chr3_0647
uniprot id: C4R559
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

644223:PAS chr2-2 0113
gene id: 644223:PAS_chr2-2_0113
uniprot id: C4R2T9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

644223:PAS chr2-1 0555
gene id: 644223:PAS_chr2-1_0555
uniprot id: C4R115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

644223:PAS chr2-1 0271
gene id: 644223:PAS_chr2-1_0271
uniprot id: C4R061
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-1 0340
gene id: 644223:PAS_chr1-1_0340
uniprot id: C4QWU5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

644223:PAS chr2-1 0693
gene id: 644223:PAS_chr2-1_0693
uniprot id: C4R1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0556
gene id: 644223:PAS_chr2-1_0556
uniprot id: C4R116
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

644223:PAS chr3 1192
gene id: 644223:PAS_chr3_1192
uniprot id: C4R4M0
names: Similarity
messages: Belongs to the hexokinase family.

644223:PAS chr2-2 0101
gene id: 644223:PAS_chr2-2_0101
uniprot id: C4R2V2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0648
gene id: 644223:PAS_chr3_0648
uniprot id: C4R560
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THI4 family.
messages: Binds 1 Fe cation per subunit.
messages: Cytoplasm
messages: During the catalytic reaction, a sulfide is transferred from Cys-227 to a reaction intermediate, generating a dehydroalanine residue.
messages: Homooctamer.
messages: Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
messages: Nucleus

644223:PAS chr4 0641
gene id: 644223:PAS_chr4_0641
uniprot id: C4R8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

644223:PAS chr2-2 0330
gene id: 644223:PAS_chr2-2_0330
uniprot id: C4R252
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0606
gene id: 644223:PAS_chr1-4_0606
uniprot id: C4QYZ1
names: Similarity
messages: Belongs to the VPS8 family.

644223:PAS chr2-1 0410
gene id: 644223:PAS_chr2-1_0410
uniprot id: C4R0K7
names: Similarity
messages: Belongs to the SDO1/SBDS family.

644223:PAS chr3 0115
gene id: 644223:PAS_chr3_0115
uniprot id: C4R3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

644223:PAS chr3 0228
gene id: 644223:PAS_chr3_0228
uniprot id: C4R3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-1 0332
gene id: 644223:PAS_chr1-1_0332
uniprot id: C4QWT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Membrane

644223:PAS chr2-2 0188
gene id: 644223:PAS_chr2-2_0188
uniprot id: C4R2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CWC2 family.
messages: Nucleus

644223:PAS chr1-4 0183
gene id: 644223:PAS_chr1-4_0183
uniprot id: C4QXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

644223:PAS chr2-2 0180
gene id: 644223:PAS_chr2-2_0180
uniprot id: C4R2L6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

644223:PAS chr1-1 0233
gene id: 644223:PAS_chr1-1_0233
uniprot id: C4QWH9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

644223:PAS chr4 0225
gene id: 644223:PAS_chr4_0225
uniprot id: C4R778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

644223:PAS chr1-1 0009
gene id: 644223:PAS_chr1-1_0009
uniprot id: C4QVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

644223:PAS chr4 0894
gene id: 644223:PAS_chr4_0894
uniprot id: C4R989
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr4 0390
gene id: 644223:PAS_chr4_0390
uniprot id: C4R7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

644223:PAS chr1-3 0179
gene id: 644223:PAS_chr1-3_0179
uniprot id: C4QVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

644223:PAS chr3 0416
gene id: 644223:PAS_chr3_0416
uniprot id: C4R4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

644223:PAS chr3 0792
gene id: 644223:PAS_chr3_0792
uniprot id: C4R5L0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

644223:PAS chr3 0586
gene id: 644223:PAS_chr3_0586
uniprot id: C4R4Z7
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

644223:PAS chr3 1092
gene id: 644223:PAS_chr3_1092
uniprot id: C4R6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

644223:PAS chr2-2 0294
gene id: 644223:PAS_chr2-2_0294
uniprot id: C4R290
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

644223:PAS chr2-1 0369
gene id: 644223:PAS_chr2-1_0369
uniprot id: C4R0G6
names: Similarity
messages: Belongs to the cullin family.

644223:PAS chr4 0955
gene id: 644223:PAS_chr4_0955
uniprot id: C4R7Q2
names: Similarity
messages: Belongs to the RICTOR family.

644223:PAS chr1-4 0370
gene id: 644223:PAS_chr1-4_0370
uniprot id: C4QY90
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0055
gene id: 644223:PAS_chr3_0055
uniprot id: C4R3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

644223:PAS chr1-1 0486
gene id: 644223:PAS_chr1-1_0486
uniprot id: C4QWI6
names: Similarity
messages: Belongs to the OPI10 family.

644223:PAS chr3 1051
gene id: 644223:PAS_chr3_1051
uniprot id: C4R6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr1-4 0417
gene id: 644223:PAS_chr1-4_0417
uniprot id: C4QYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

644223:PAS chr1-1 0436
gene id: 644223:PAS_chr1-1_0436
uniprot id: C4QX40
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

644223:PAS chr3 0408
gene id: 644223:PAS_chr3_0408
uniprot id: C4R4H1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the alternative oxidase family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.

644223:PAS chr4 0731
gene id: 644223:PAS_chr4_0731
uniprot id: C4R8R8
names: Similarity
messages: Belongs to the AAA ATPase family.

644223:PAS chr1-4 0027
gene id: 644223:PAS_chr1-4_0027
uniprot id: C4QX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

644223:PAS chr1-1 0028
gene id: 644223:PAS_chr1-1_0028
uniprot id: C4QVV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr1-4 0278
gene id: 644223:PAS_chr1-4_0278
uniprot id: C4QXZ0
names: Similarity
messages: Belongs to the OSBP family.

644223:PAS chr2-1 0699
gene id: 644223:PAS_chr2-1_0699
uniprot id: C4R1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

644223:PAS chr1-4 0549
gene id: 644223:PAS_chr1-4_0549
uniprot id: C4QYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

644223:PAS chr3 1101
gene id: 644223:PAS_chr3_1101
uniprot id: C4R6I1
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

644223:PAS chr4 0993
gene id: 644223:PAS_chr4_0993
uniprot id: C4R8Y1
names: Similarity
messages: Belongs to the VPS25 family.

644223:PAS chr1-4 0188
gene id: 644223:PAS_chr1-4_0188
uniprot id: C4QXP8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr1-4 0123
gene id: 644223:PAS_chr1-4_0123
uniprot id: C4QXH9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

644223:PAS FragB 0029
gene id: 644223:PAS_FragB_0029
uniprot id: C4QZ85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0741
gene id: 644223:PAS_chr2-1_0741
uniprot id: C4R1L7
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

644223:PAS chr4 0580
gene id: 644223:PAS_chr4_0580
uniprot id: C4R8B4
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

644223:PAS chr3 0999
gene id: 644223:PAS_chr3_0999
uniprot id: C4R675
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0077
gene id: 644223:PAS_chr3_0077
uniprot id: C4R3H4
names: Similarity
messages: Belongs to the eIF-2-alpha family.

644223:PAS chr2-1 0732
gene id: 644223:PAS_chr2-1_0732
uniprot id: C4R1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).

644223:PAS chr4 0112
gene id: 644223:PAS_chr4_0112
uniprot id: C4R6W2
names: Similarity
messages: Belongs to the threonine aldolase family.

644223:PAS chr1-4 0552
gene id: 644223:PAS_chr1-4_0552
uniprot id: C4QYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

644223:PAS chr3 0144
gene id: 644223:PAS_chr3_0144
uniprot id: C4R3N8
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

644223:PAS chr3 0187
gene id: 644223:PAS_chr3_0187
uniprot id: C4R3T1
names: Similarity
messages: Belongs to the TMEM14 family.

644223:PAS chr3 0345
gene id: 644223:PAS_chr3_0345
uniprot id: C4R4A0
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

644223:PAS chr2-1 0321
gene id: 644223:PAS_chr2-1_0321
uniprot id: C4R0B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

644223:PAS chr2-1 0818
gene id: 644223:PAS_chr2-1_0818
uniprot id: C4R000
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

644223:PAS chr1-1 0130
gene id: 644223:PAS_chr1-1_0130
uniprot id: C4QW71
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

644223:PAS chr3 0943
gene id: 644223:PAS_chr3_0943
uniprot id: C4R617
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

644223:PAS chr3 0856
gene id: 644223:PAS_chr3_0856
uniprot id: C4R5S2
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

644223:PAS chr2-2 0368
gene id: 644223:PAS_chr2-2_0368
uniprot id: C4R213
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

644223:PAS chr1-1 0500
gene id: 644223:PAS_chr1-1_0500
uniprot id: C4QWW8
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

644223:PAS chr4 0343
gene id: 644223:PAS_chr4_0343
uniprot id: C4R7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

644223:PAS chr2-1 0246
gene id: 644223:PAS_chr2-1_0246
uniprot id: C4R034
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

644223:PAS chr3 0495
gene id: 644223:PAS_chr3_0495
uniprot id: C4R4Q7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0710
gene id: 644223:PAS_chr4_0710
uniprot id: C4R8P6
names: Similarity
messages: Belongs to the WD repeat rae1 family.

644223:PAS chr2-1 0125
gene id: 644223:PAS_chr2-1_0125
uniprot id: C4QZQ7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

644223:PAS chr1-4 0638
gene id: 644223:PAS_chr1-4_0638
uniprot id: C4QZ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrion inner membrane
messages: Probable mitochondrial mRNA stabilization factor.

644223:PAS chr3 1235
gene id: 644223:PAS_chr3_1235
uniprot id: C4R5W4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0730
gene id: 644223:PAS_chr4_0730
uniprot id: C4R8R7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

644223:PAS chr1-1 0259
gene id: 644223:PAS_chr1-1_0259
uniprot id: C4QWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

644223:PAS chr2-2 0465
gene id: 644223:PAS_chr2-2_0465
uniprot id: C4R2P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

644223:PAS chr3 0290
gene id: 644223:PAS_chr3_0290
uniprot id: C4R444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS30 family.
messages: Membrane
messages: Vacuole membrane

644223:PAS chr3 0148
gene id: 644223:PAS_chr3_0148
uniprot id: C4R3P1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr2-1 0552
gene id: 644223:PAS_chr2-1_0552
uniprot id: C4R112
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

644223:PAS chr4 0701
gene id: 644223:PAS_chr4_0701
uniprot id: C4R8N8
names: Similarity
messages: Belongs to the bystin family.

644223:PAS chr1-4 0155
gene id: 644223:PAS_chr1-4_0155
uniprot id: C4QXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

644223:PAS chr3 0409
gene id: 644223:PAS_chr3_0409
uniprot id: C4R4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

644223:PAS chr3 1256
gene id: 644223:PAS_chr3_1256
uniprot id: C4R6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Membrane
messages: Vacuole membrane

644223:PAS chr4 0539
gene id: 644223:PAS_chr4_0539
uniprot id: C4R874
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0209
gene id: 644223:PAS_chr2-2_0209
uniprot id: C4R2I4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr2-1 0111
gene id: 644223:PAS_chr2-1_0111
uniprot id: C4QZP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

644223:PAS chr2-1 0166
gene id: 644223:PAS_chr2-1_0166
uniprot id: C4QZU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0745
gene id: 644223:PAS_chr3_0745
uniprot id: C4R5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

644223:PAS chr2-2 0409
gene id: 644223:PAS_chr2-2_0409
uniprot id: C4R1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

644223:PAS chr4 0122
gene id: 644223:PAS_chr4_0122
uniprot id: C4R6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0735
gene id: 644223:PAS_chr3_0735
uniprot id: C4R5E8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0244
gene id: 644223:PAS_chr3_0244
uniprot id: C4R3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr2-1 0886
gene id: 644223:PAS_chr2-1_0886
uniprot id: C4R1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

644223:PAS chr4 0349
gene id: 644223:PAS_chr4_0349
uniprot id: C4R7L8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1073
gene id: 644223:PAS_chr3_1073
uniprot id: C4R6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

644223:PAS chr1-4 0498
gene id: 644223:PAS_chr1-4_0498
uniprot id: C4QYM8
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

644223:PAS chr4 0810
gene id: 644223:PAS_chr4_0810
uniprot id: C4R906
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0299
gene id: 644223:PAS_chr2-2_0299
uniprot id: C4R284
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0941
gene id: 644223:PAS_chr4_0941
uniprot id: C4R7G1
names: Subcellular Location Annotation
messages: Peroxisome membrane

644223:PAS chr4 0282
gene id: 644223:PAS_chr4_0282
uniprot id: C4R7E3
names: Similarity
messages: Belongs to the TOG/XMAP215 family.

644223:PAS chr1-4 0172
gene id: 644223:PAS_chr1-4_0172
uniprot id: C4QXN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

644223:PAS chr4 0635
gene id: 644223:PAS_chr4_0635
uniprot id: C4R8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

644223:PAS chr3 0272
gene id: 644223:PAS_chr3_0272
uniprot id: C4R425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr1-4 0146
gene id: 644223:PAS_chr1-4_0146
uniprot id: C4QXK2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0912
gene id: 644223:PAS_chr4_0912
uniprot id: C4R6M3
names: Similarity
messages: Belongs to the NAD kinase family.

644223:PAS chr1-4 0529
gene id: 644223:PAS_chr1-4_0529
uniprot id: C4QYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

644223:PAS chr2-1 0113
gene id: 644223:PAS_chr2-1_0113
uniprot id: C4QZP3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

644223:PAS chr1-4 0353
gene id: 644223:PAS_chr1-4_0353
uniprot id: C4QY72
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

644223:PAS chr2-1 0411
gene id: 644223:PAS_chr2-1_0411
uniprot id: C4R0K8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0376
gene id: 644223:PAS_chr3_0376
uniprot id: C4R4D4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr4 0784
gene id: 644223:PAS_chr4_0784
uniprot id: C4R8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

644223:PAS chr3 0862
gene id: 644223:PAS_chr3_0862
uniprot id: C4R5T0
names: Subcellular Location Annotation
messages: Mitochondrion

644223:PAS chr3 0270
gene id: 644223:PAS_chr3_0270
uniprot id: C4R423
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

644223:PAS chr2-1 0599
gene id: 644223:PAS_chr2-1_0599
uniprot id: C4R162
names: Similarity
messages: Belongs to the DOCK family.

644223:PAS chr3 0136
gene id: 644223:PAS_chr3_0136
uniprot id: C4R3M9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

644223:PAS chr2-1 0861
gene id: 644223:PAS_chr2-1_0861
uniprot id: C4R121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: nucleolus

644223:PAS chr2-1 0513
gene id: 644223:PAS_chr2-1_0513
uniprot id: C4R0X1
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

644223:PAS chr3 0099
gene id: 644223:PAS_chr3_0099
uniprot id: C4R3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr1-4 0429
gene id: 644223:PAS_chr1-4_0429
uniprot id: C4QYF6
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

644223:PAS chr2-1 0588
gene id: 644223:PAS_chr2-1_0588
uniprot id: C4R150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

644223:PAS chr4 0759
gene id: 644223:PAS_chr4_0759
uniprot id: C4R8U8
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

644223:PAS chr1-4 0555
gene id: 644223:PAS_chr1-4_0555
uniprot id: C4QYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

644223:PAS chr1-4 0203
gene id: 644223:PAS_chr1-4_0203
uniprot id: C4QXR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

644223:PAS chr2-1 0244
gene id: 644223:PAS_chr2-1_0244
uniprot id: C4R032
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

644223:PAS chr1-3 0056
gene id: 644223:PAS_chr1-3_0056
uniprot id: C4QV38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

644223:PAS chr3 0024
gene id: 644223:PAS_chr3_0024
uniprot id: C4R3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644223:PAS chr4 0310
gene id: 644223:PAS_chr4_0310
uniprot id: C4R7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

644223:PAS chr3 1239
gene id: 644223:PAS_chr3_1239
uniprot id: C4R5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

644223:PAS chr2-2 0339
gene id: 644223:PAS_chr2-2_0339
uniprot id: C4R243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

644223:PAS chr4 0370
gene id: 644223:PAS_chr4_0370
uniprot id: C4R7P0
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0284
gene id: 644223:PAS_chr2-2_0284
uniprot id: C4R2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

644223:PAS chr1-1 0179
gene id: 644223:PAS_chr1-1_0179
uniprot id: C4QWC1
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-4 0049
gene id: 644223:PAS_chr1-4_0049
uniprot id: C4QXA7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

644223:PAS chr3 0265
gene id: 644223:PAS_chr3_0265
uniprot id: C4R417
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

644223:PAS chr1-1 0412
gene id: 644223:PAS_chr1-1_0412
uniprot id: C4QX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-2 0172
gene id: 644223:PAS_chr2-2_0172
uniprot id: C4R2M7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

644223:PAS chr4 0838
gene id: 644223:PAS_chr4_0838
uniprot id: C4R933
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0006
gene id: 644223:PAS_chr2-1_0006
uniprot id: C4QZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr3 0380
gene id: 644223:PAS_chr3_0380
uniprot id: C4R4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS FragB 0023
gene id: 644223:PAS_FragB_0023
uniprot id: C4QZ79
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0722
gene id: 644223:PAS_chr3_0722
uniprot id: C4R5D4
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

644223:PAS chr3 0213
gene id: 644223:PAS_chr3_0213
uniprot id: C4R3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

644223:PAS chr1-4 0039
gene id: 644223:PAS_chr1-4_0039
uniprot id: C4QX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I LYR family.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0322
gene id: 644223:PAS_chr2-1_0322
uniprot id: C4R0B4
names: Similarity
messages: Belongs to the calreticulin family.

644223:PAS chr2-1 0055
gene id: 644223:PAS_chr2-1_0055
uniprot id: C4QZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644223:PAS chr1-4 0013
gene id: 644223:PAS_chr1-4_0013
uniprot id: P52710
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Involved in degradation of small peptides.
messages: Vacuole

644223:PAS chr1-3 0212
gene id: 644223:PAS_chr1-3_0212
uniprot id: C4QVK3
names: Similarity
messages: Belongs to the cytochrome P450 family.

644223:PAS chr2-1 0095
gene id: 644223:PAS_chr2-1_0095
uniprot id: C4QZM3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0725
gene id: 644223:PAS_chr3_0725
uniprot id: C4R5D8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS chr1-4 0024
gene id: 644223:PAS_chr1-4_0024
uniprot id: C4QX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

644223:PAS chr2-1 0256
gene id: 644223:PAS_chr2-1_0256
uniprot id: C4R044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

644223:PAS chr4 0781
gene id: 644223:PAS_chr4_0781
uniprot id: C4R8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

644223:PAS chr4 0717
gene id: 644223:PAS_chr4_0717
uniprot id: C4R8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

644223:PAS chr1-4 0083
gene id: 644223:PAS_chr1-4_0083
uniprot id: C4QXD9
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

644223:PAS c131 0007
gene id: 644223:PAS_c131_0007
uniprot id: C4R385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STAM family.
messages: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
messages: Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
messages: Endosome membrane
messages: Membrane

644223:PAS c131 0010
gene id: 644223:PAS_c131_0010
uniprot id: C4R388
names: Function
names: Similarity
messages: Belongs to the BYE1 family.
messages: Negative regulator of transcription elongation.

644223:PAS chr2-2 0168
gene id: 644223:PAS_chr2-2_0168
uniprot id: C4R2N2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

644223:PAS chr1-4 0248
gene id: 644223:PAS_chr1-4_0248
uniprot id: C4QXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0538
gene id: 644223:PAS_chr2-1_0538
uniprot id: C4R0Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr2-2 0231
gene id: 644223:PAS_chr2-2_0231
uniprot id: C4R2G1
names: Similarity
messages: Belongs to the TAF11 family.

644223:PAS chr1-4 0092
gene id: 644223:PAS_chr1-4_0092
uniprot id: C4QXE8
names: Similarity
messages: Belongs to the RNase PH family.

644223:PAS chr3 1229
gene id: 644223:PAS_chr3_1229
uniprot id: C4R5S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

644223:PAS chr1-1 0083
gene id: 644223:PAS_chr1-1_0083
uniprot id: C4QW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

644223:PAS chr2-2 0379
gene id: 644223:PAS_chr2-2_0379
uniprot id: C4R202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

644223:PAS chr3 0041
gene id: 644223:PAS_chr3_0041
uniprot id: C4R3D2
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-1 0154
gene id: 644223:PAS_chr1-1_0154
uniprot id: C4QW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

644223:PAS chr3 0632
gene id: 644223:PAS_chr3_0632
uniprot id: C4R544
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

644223:PAS chr2-2 0174
gene id: 644223:PAS_chr2-2_0174
uniprot id: C4R2M4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

644223:PAS chr2-1 0383
gene id: 644223:PAS_chr2-1_0383
uniprot id: C4R0I1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

644223:PAS chr2-1 0478
gene id: 644223:PAS_chr2-1_0478
uniprot id: C4R0T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

644223:PAS chr1-4 0356
gene id: 644223:PAS_chr1-4_0356
uniprot id: C4QY76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
messages: nucleolus

644223:PAS chr4 0307
gene id: 644223:PAS_chr4_0307
uniprot id: C4R7H1
names: Similarity
messages: Belongs to the SUN family.

644223:PAS FragD 0024
gene id: 644223:PAS_FragD_0024
uniprot id: C4R9A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuole membrane

644223:PAS chr3 0549
gene id: 644223:PAS_chr3_0549
uniprot id: C4R4W1
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-4 0703
gene id: 644223:PAS_chr1-4_0703
uniprot id: C4QYV7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0431
gene id: 644223:PAS_chr4_0431
uniprot id: C4R7V7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0552
gene id: 644223:PAS_chr4_0552
uniprot id: C4R887
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS chr3 0832
gene id: 644223:PAS_chr3_0832
uniprot id: C4R5P8
names: Similarity
messages: Belongs to the transketolase family.

644223:PAS chr2-2 0120
gene id: 644223:PAS_chr2-2_0120
uniprot id: C4R2T2
names: Similarity
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.

644223:PAS chr4 0745
gene id: 644223:PAS_chr4_0745
uniprot id: C4R8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

644223:PAS chr3 0414
gene id: 644223:PAS_chr3_0414
uniprot id: C4R4H7
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

644223:PAS chr1-4 0066
gene id: 644223:PAS_chr1-4_0066
uniprot id: C4QXC2
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

644223:PAS chr1-4 0669
gene id: 644223:PAS_chr1-4_0669
uniprot id: C4QY21
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

644223:PAS chr4 0901
gene id: 644223:PAS_chr4_0901
uniprot id: C4R996
names: Similarity
messages: Belongs to the RRP15 family.

644223:PAS chr1-1 0076
gene id: 644223:PAS_chr1-1_0076
uniprot id: C4QW12
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

644223:PAS chr3 0423
gene id: 644223:PAS_chr3_0423
uniprot id: C4R4I6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0068
gene id: 644223:PAS_chr1-4_0068
uniprot id: C4QXC4
names: Similarity
messages: Belongs to the MIX23 family.

644223:PAS chr4 0558
gene id: 644223:PAS_chr4_0558
uniprot id: C4R893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0503
gene id: 644223:PAS_chr2-1_0503
uniprot id: C4R0W0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

644223:PAS chr4 0741
gene id: 644223:PAS_chr4_0741
uniprot id: C4R8S8
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

644223:PAS chr1-4 0673
gene id: 644223:PAS_chr1-4_0673
uniprot id: C4QY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

644223:PAS chr4 0302
gene id: 644223:PAS_chr4_0302
uniprot id: C4R7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

644223:PAS chr2-1 0461
gene id: 644223:PAS_chr2-1_0461
uniprot id: C4R0R4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0576
gene id: 644223:PAS_chr1-4_0576
uniprot id: C4QYV9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

644223:PAS chr4 0549
gene id: 644223:PAS_chr4_0549
uniprot id: C4R884
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0674
gene id: 644223:PAS_chr2-1_0674
uniprot id: C4R1E6
names: Similarity
messages: Belongs to the CDC73 family.

644223:PAS chr2-2 0119
gene id: 644223:PAS_chr2-2_0119
uniprot id: C4R2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

644223:PAS chr1-4 0215
gene id: 644223:PAS_chr1-4_0215
uniprot id: C4QXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

644223:PAS chr2-2 0131
gene id: 644223:PAS_chr2-2_0131
uniprot id: C4R2S1
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

644223:PAS chr3 0350
gene id: 644223:PAS_chr3_0350
uniprot id: C4R4A6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0759
gene id: 644223:PAS_chr2-1_0759
uniprot id: C4R1N8
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

644223:PAS chr2-2 0394
gene id: 644223:PAS_chr2-2_0394
uniprot id: C4R1Z0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

644223:PAS chr2-2 0298
gene id: 644223:PAS_chr2-2_0298
uniprot id: C4R285
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

644223:PAS chr3 1112
gene id: 644223:PAS_chr3_1112
uniprot id: C4R6J3
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

644223:PAS chr2-1 0131
gene id: 644223:PAS_chr2-1_0131
uniprot id: C4QZR3
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

644223:PAS chr1-1 0150
gene id: 644223:PAS_chr1-1_0150
uniprot id: C4QW91
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

644223:PAS chr4 0619
gene id: 644223:PAS_chr4_0619
uniprot id: C4R8F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

644223:PAS chr3 0346
gene id: 644223:PAS_chr3_0346
uniprot id: C4R4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

644223:PAS chr4 0269
gene id: 644223:PAS_chr4_0269
uniprot id: C4R7C8
names: Similarity
messages: Belongs to the CWC22 family.

644223:PAS chr2-2 0030
gene id: 644223:PAS_chr2-2_0030
uniprot id: C4R332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

644223:PAS c131 0006
gene id: 644223:PAS_c131_0006
uniprot id: C4R384
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

644223:PAS chr3 0768
gene id: 644223:PAS_chr3_0768
uniprot id: C4R5I4
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

644223:PAS chr1-1 0414
gene id: 644223:PAS_chr1-1_0414
uniprot id: C4QX18
names: Similarity
messages: Belongs to the LOC1 family.

644223:PAS chr2-2 0074
gene id: 644223:PAS_chr2-2_0074
uniprot id: C4R2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

644223:PAS chr1-1 0187
gene id: 644223:PAS_chr1-1_0187
uniprot id: C4QWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

644223:PAS chr2-1 0783
gene id: 644223:PAS_chr2-1_0783
uniprot id: C4R1R7
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

644223:PAS chr3 0242
gene id: 644223:PAS_chr3_0242
uniprot id: C4R3Z3
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

644223:PAS chr3 0051
gene id: 644223:PAS_chr3_0051
uniprot id: C4R3E4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0375
gene id: 644223:PAS_chr2-1_0375
uniprot id: C4R0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

644223:PAS chr3 0092
gene id: 644223:PAS_chr3_0092
uniprot id: C4R3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

644223:PAS chr3 0698
gene id: 644223:PAS_chr3_0698
uniprot id: C4R5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

644223:PAS chr3 0056
gene id: 644223:PAS_chr3_0056
uniprot id: C4R3E9
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

644223:PAS chr1-1 0459
gene id: 644223:PAS_chr1-1_0459
uniprot id: C4QVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

644223:PAS chr2-2 0462
gene id: 644223:PAS_chr2-2_0462
uniprot id: C4R2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0129
gene id: 644223:PAS_chr2-1_0129
uniprot id: C4QZR1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0094
gene id: 644223:PAS_chr4_0094
uniprot id: C4R6U6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

644223:PAS chr3 0614
gene id: 644223:PAS_chr3_0614
uniprot id: C4R525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

644223:PAS chr1-4 0475
gene id: 644223:PAS_chr1-4_0475
uniprot id: C4QYK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr2-1 0657
gene id: 644223:PAS_chr2-1_0657
uniprot id: C4R1C8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

644223:PAS chr2-2 0096
gene id: 644223:PAS_chr2-2_0096
uniprot id: C4R2V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YME2 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.

644223:PAS chr4 0859
gene id: 644223:PAS_chr4_0859
uniprot id: C4R953
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0313
gene id: 644223:PAS_chr3_0313
uniprot id: C4R467
names: Similarity
messages: Belongs to the Mo25 family.

644223:PAS chr1-1 0294
gene id: 644223:PAS_chr1-1_0294
uniprot id: C4QWP7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

644223:PAS chr2-1 0061
gene id: 644223:PAS_chr2-1_0061
uniprot id: C4QZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

644223:PAS FragB 0033
gene id: 644223:PAS_FragB_0033
uniprot id: C4QZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space

644223:PAS chr1-4 0476
gene id: 644223:PAS_chr1-4_0476
uniprot id: C4QYK5
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

644223:PAS chr4 0879
gene id: 644223:PAS_chr4_0879
uniprot id: C4R975
names: Similarity
messages: Belongs to the SLA2 family.

644223:PAS chr1-4 0548
gene id: 644223:PAS_chr1-4_0548
uniprot id: C4QYT0
names: Similarity
messages: Belongs to the peptidase S8 family.

644223:PAS chr3 0426
gene id: 644223:PAS_chr3_0426
uniprot id: C4R4J0
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.

644223:PAS chr1-4 0333
gene id: 644223:PAS_chr1-4_0333
uniprot id: C4QY53
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0846
gene id: 644223:PAS_chr4_0846
uniprot id: C4R940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr2-2 0104
gene id: 644223:PAS_chr2-2_0104
uniprot id: C4R2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr1-4 0642
gene id: 644223:PAS_chr1-4_0642
uniprot id: C4QZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

644223:PAS chr1-4 0504
gene id: 644223:PAS_chr1-4_0504
uniprot id: C4QYN4
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

644223:PAS chr2-1 0385
gene id: 644223:PAS_chr2-1_0385
uniprot id: C4R0I3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0253
gene id: 644223:PAS_chr3_0253
uniprot id: C4R404
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

644223:PAS chr1-1 0275
gene id: 644223:PAS_chr1-1_0275
uniprot id: C4QWM2
names: Similarity
messages: Belongs to the CCS1 family.

644223:PAS chr3 0619
gene id: 644223:PAS_chr3_0619
uniprot id: C4R530
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

644223:PAS chr3 0685
gene id: 644223:PAS_chr3_0685
uniprot id: C4R598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

644223:PAS chr2-2 0420
gene id: 644223:PAS_chr2-2_0420
uniprot id: C4R1W5
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

644223:PAS chr4 0748
gene id: 644223:PAS_chr4_0748
uniprot id: C4R8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

644223:PAS chr3 0186
gene id: 644223:PAS_chr3_0186
uniprot id: C4R3T0
names: Similarity
messages: Belongs to the DSD1 family.

644223:PAS chr2-2 0429
gene id: 644223:PAS_chr2-2_0429
uniprot id: C4R1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

644223:PAS chr3 0795
gene id: 644223:PAS_chr3_0795
uniprot id: C4R5L3
names: Similarity
messages: Belongs to the SH3YL1 family.

644223:PAS chr2-1 0172
gene id: 644223:PAS_chr2-1_0172
uniprot id: C4QZV5
names: Similarity
messages: Belongs to the peptidase S8 family.

644223:PAS FragB 0027
gene id: 644223:PAS_FragB_0027
uniprot id: C4QZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

644223:PAS chr2-2 0412
gene id: 644223:PAS_chr2-2_0412
uniprot id: C4R1X2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

644223:PAS chr4 0177
gene id: 644223:PAS_chr4_0177
uniprot id: C4R728
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0915
gene id: 644223:PAS_chr3_0915
uniprot id: C4R5Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

644223:PAS chr2-2 0383
gene id: 644223:PAS_chr2-2_0383
uniprot id: C4R1Z8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0108
gene id: 644223:PAS_chr4_0108
uniprot id: C4R6V9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0126
gene id: 644223:PAS_chr1-3_0126
uniprot id: C4QVB3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0368
gene id: 644223:PAS_chr2-1_0368
uniprot id: C4R0G5
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

644223:PAS chr1-4 0315
gene id: 644223:PAS_chr1-4_0315
uniprot id: C4QY33
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr1-4 0254
gene id: 644223:PAS_chr1-4_0254
uniprot id: C4QXW5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

644223:PAS chr2-2 0245
gene id: 644223:PAS_chr2-2_0245
uniprot id: C4R2E5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr2-1 0574
gene id: 644223:PAS_chr2-1_0574
uniprot id: C4R136
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0224
gene id: 644223:PAS_chr4_0224
uniprot id: C4R777
names: Similarity
messages: Belongs to the CNOT9 family.

644223:PAS chr4 0344
gene id: 644223:PAS_chr4_0344
uniprot id: C4R7L2
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

644223:PAS chr3 0292
gene id: 644223:PAS_chr3_0292
uniprot id: C4R447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

644223:PAS chr1-1 0444
gene id: 644223:PAS_chr1-1_0444
uniprot id: C4QX48
names: Similarity
messages: Belongs to the RMD1/sif2 family.

644223:PAS chr1-3 0149
gene id: 644223:PAS_chr1-3_0149
uniprot id: C4QVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

644223:PAS chr4 0821
gene id: 644223:PAS_chr4_0821
uniprot id: P04842
names: Domain
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GMC oxidoreductase family.
messages: Homooctamer. Assembles only after import into the peroxisomal matrix, fails to assemble in the cytoplasm.
messages: Induced by methanol. Subject to strong carbon catabolite repression.
messages: Major isoform of alcohol oxidase, which catalyzes the oxidation of methanol to formaldehyde and hydrogen peroxide, the first step in the methanol utilization pathway of methylotrophic yeasts.
messages: Peroxisome matrix
messages: The C-terminal peroxisomal targeting signal (PTS) is essential for the efficient targeting and import of AOX into peroxisomes via the PTS1 pathway.

644223:PAS chr3 0066
gene id: 644223:PAS_chr3_0066
uniprot id: C4R3G0
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

644223:PAS chr1-4 0154
gene id: 644223:PAS_chr1-4_0154
uniprot id: C4QXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

644223:PAS chr3 0949
gene id: 644223:PAS_chr3_0949
uniprot id: C4R624
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr1-3 0237
gene id: 644223:PAS_chr1-3_0237
uniprot id: C4QVM6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-4 0411
gene id: 644223:PAS_chr1-4_0411
uniprot id: C4QYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

644223:PAS chr2-1 0174
gene id: 644223:PAS_chr2-1_0174
uniprot id: C4QZV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S10 family.
messages: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).
messages: trans-Golgi network membrane

644223:PAS chr4 0891
gene id: 644223:PAS_chr4_0891
uniprot id: C4R986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

644223:PAS chr3 0904
gene id: 644223:PAS_chr3_0904
uniprot id: C4R5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

644223:PAS chr1-1 0356
gene id: 644223:PAS_chr1-1_0356
uniprot id: C4QWV9
names: Similarity
messages: Belongs to the DapA family.

644223:PAS chr3 0960
gene id: 644223:PAS_chr3_0960
uniprot id: C4R635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

644223:PAS chr4 0038
gene id: 644223:PAS_chr4_0038
uniprot id: C4R6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

644223:PAS chr1-3 0271
gene id: 644223:PAS_chr1-3_0271
uniprot id: C4QVR2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

644223:PAS chr3 0169
gene id: 644223:PAS_chr3_0169
uniprot id: C4R3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

644223:PAS chr2-2 0088
gene id: 644223:PAS_chr2-2_0088
uniprot id: C4R2W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

644223:PAS chr3 0440
gene id: 644223:PAS_chr3_0440
uniprot id: C4R4K2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

644223:PAS chr2-2 0121
gene id: 644223:PAS_chr2-2_0121
uniprot id: C4R2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

644223:PAS chr4 0775
gene id: 644223:PAS_chr4_0775
uniprot id: C4R8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0161
gene id: 644223:PAS_chr2-1_0161
uniprot id: C4QZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

644223:PAS chr1-4 0329
gene id: 644223:PAS_chr1-4_0329
uniprot id: C4QY49
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

644223:PAS chr4 0545
gene id: 644223:PAS_chr4_0545
uniprot id: C4R880
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr4 0096
gene id: 644223:PAS_chr4_0096
uniprot id: C4R6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS c131 0014
gene id: 644223:PAS_c131_0014
uniprot id: C4R392
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

644223:PAS chr3 0794
gene id: 644223:PAS_chr3_0794
uniprot id: C4R5L1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

644223:PAS chr1-3 0300
gene id: 644223:PAS_chr1-3_0300
uniprot id: C4QVD0
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

644223:PAS chr1-4 0662
gene id: 644223:PAS_chr1-4_0662
uniprot id: C4QXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

644223:PAS chr4 0208
gene id: 644223:PAS_chr4_0208
uniprot id: C4R759
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

644223:PAS chr1-4 0425
gene id: 644223:PAS_chr1-4_0425
uniprot id: C4QYF2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS chr3 0964
gene id: 644223:PAS_chr3_0964
uniprot id: C4R639
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr4 0402
gene id: 644223:PAS_chr4_0402
uniprot id: C4R7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

644223:PAS chr3 1132
gene id: 644223:PAS_chr3_1132
uniprot id: C4R366
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr1-4 0562
gene id: 644223:PAS_chr1-4_0562
uniprot id: C4QYU4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0172
gene id: 644223:PAS_chr1-3_0172
uniprot id: C4QVG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

644223:PAS chr4 0670
gene id: 644223:PAS_chr4_0670
uniprot id: C4R8K4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0466
gene id: 644223:PAS_chr2-1_0466
uniprot id: C4R0S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

644223:PAS chr2-2 0199
gene id: 644223:PAS_chr2-2_0199
uniprot id: C4R2J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

644223:PAS chr4 0019
gene id: 644223:PAS_chr4_0019
uniprot id: C4R6M0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0660
gene id: 644223:PAS_chr1-4_0660
uniprot id: C4QXN5
names: Similarity
messages: Belongs to the IML2 family.

644223:PAS chr2-1 0695
gene id: 644223:PAS_chr2-1_0695
uniprot id: C4R1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

644223:PAS chr1-1 0085
gene id: 644223:PAS_chr1-1_0085
uniprot id: C4QW22
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0899
gene id: 644223:PAS_chr3_0899
uniprot id: C4R5X1
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

644223:PAS chr2-2 0162
gene id: 644223:PAS_chr2-2_0162
uniprot id: C4R2N9
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

644223:PAS chr1-4 0142
gene id: 644223:PAS_chr1-4_0142
uniprot id: C4QXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

644223:PAS chr1-4 0469
gene id: 644223:PAS_chr1-4_0469
uniprot id: C4QYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

644223:PAS chr1-1 0041
gene id: 644223:PAS_chr1-1_0041
uniprot id: C4QVX6
names: Function
names: Induction
names: Subunit
messages: Expression is induced by methanol and glucose.
messages: Interacts with ATG28.
messages: Micropexophagy-specific protein required for efficient micropexophagic apparatus (MIPA) formation but not for general autophagy.

644223:PAS chr1-4 0298
gene id: 644223:PAS_chr1-4_0298
uniprot id: C4QY15
names: Similarity
messages: Belongs to the PP2C family.

644223:PAS chr4 0093
gene id: 644223:PAS_chr4_0093
uniprot id: C4R6U5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0211
gene id: 644223:PAS_chr2-1_0211
uniprot id: C4QZZ5
names: Similarity
messages: Belongs to the beclin family.

644223:PAS chr1-4 0043
gene id: 644223:PAS_chr1-4_0043
uniprot id: C4QXA1
names: Similarity
messages: Belongs to the p23/wos2 family.

644223:PAS chr3 0091
gene id: 644223:PAS_chr3_0091
uniprot id: C4R3I6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

644223:PAS chr4 0900
gene id: 644223:PAS_chr4_0900
uniprot id: C4R995
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

644223:PAS chr2-2 0492
gene id: 644223:PAS_chr2-2_0492
uniprot id: C4R277
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

644223:PAS chr1-1 0230
gene id: 644223:PAS_chr1-1_0230
uniprot id: C4QWH6
names: Subunit
messages: Monomer.

644223:PAS chr3 1142
gene id: 644223:PAS_chr3_1142
uniprot id: C4R377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-1 0309
gene id: 644223:PAS_chr1-1_0309
uniprot id: C4QWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

644223:PAS chr2-1 0395
gene id: 644223:PAS_chr2-1_0395
uniprot id: C4R0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

644223:PAS chr3 0082
gene id: 644223:PAS_chr3_0082
uniprot id: C4R3H8
names: Similarity
messages: Belongs to the enolase family.

644223:PAS chr2-1 0307
gene id: 644223:PAS_chr2-1_0307
uniprot id: C4R098
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

644223:PAS chr1-1 0416
gene id: 644223:PAS_chr1-1_0416
uniprot id: C4QX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLT11 family.
messages: Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.
messages: Nucleus

644223:PAS chr3 0471
gene id: 644223:PAS_chr3_0471
uniprot id: C4R4N4
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

644223:PAS chr4 0537
gene id: 644223:PAS_chr4_0537
uniprot id: C4R872
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0671
gene id: 644223:PAS_chr2-1_0671
uniprot id: C4R1E3
names: Similarity
messages: Belongs to the TFP11/STIP family.

644223:PAS chr1-4 0126
gene id: 644223:PAS_chr1-4_0126
uniprot id: C4QXI2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

644223:PAS chr4 0175
gene id: 644223:PAS_chr4_0175
uniprot id: C4R725
names: Similarity
messages: Belongs to the cytochrome b5 family.

644223:PAS chr3 0707
gene id: 644223:PAS_chr3_0707
uniprot id: C4R5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

644223:PAS chr1-1 0128
gene id: 644223:PAS_chr1-1_0128
uniprot id: C4QW67
names: Similarity
messages: Belongs to the CAND family.

644223:PAS chr3 0982
gene id: 644223:PAS_chr3_0982
uniprot id: C4R659
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0864
gene id: 644223:PAS_chr2-1_0864
uniprot id: C4R141
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

644223:PAS chr3 0767
gene id: 644223:PAS_chr3_0767
uniprot id: C4R5I2
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

644223:PAS chr1-4 0413
gene id: 644223:PAS_chr1-4_0413
uniprot id: C4QYD8
names: Subcellular Location Annotation
messages: Peroxisome membrane

644223:PAS chr3 0776
gene id: 644223:PAS_chr3_0776
uniprot id: C4R5J2
names: Similarity
messages: Belongs to the BLM10 family.

644223:PAS chr1-4 0106
gene id: 644223:PAS_chr1-4_0106
uniprot id: C4QXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

644223:PAS chr2-1 0160
gene id: 644223:PAS_chr2-1_0160
uniprot id: C4QZU2
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

644223:PAS chr1-1 0010
gene id: 644223:PAS_chr1-1_0010
uniprot id: C4QVU0
names: Similarity
messages: Belongs to the peptidase C48 family.

644223:PAS chr4 0758
gene id: 644223:PAS_chr4_0758
uniprot id: C4R8U7
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

644223:PAS chr1-3 0028
gene id: 644223:PAS_chr1-3_0028
uniprot id: C4QV10
names: Similarity
messages: Belongs to the PPase family.

644223:PAS chr2-1 0079
gene id: 644223:PAS_chr2-1_0079
uniprot id: C4QZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

644223:PAS chr3 1139
gene id: 644223:PAS_chr3_1139
uniprot id: C4R374
names: Similarity
messages: Belongs to the sorting nexin family.

644223:PAS chr3 0369
gene id: 644223:PAS_chr3_0369
uniprot id: C4R4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

644223:PAS chr1-4 0115
gene id: 644223:PAS_chr1-4_0115
uniprot id: C4QXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0756
gene id: 644223:PAS_chr2-1_0756
uniprot id: C4R1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

644223:PAS chr4 0794
gene id: 644223:PAS_chr4_0794
uniprot id: C4R8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

644223:PAS chr3 1135
gene id: 644223:PAS_chr3_1135
uniprot id: C4R369
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

644223:PAS chr4 0650
gene id: 644223:PAS_chr4_0650
uniprot id: C4R8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

644223:PAS chr2-2 0258
gene id: 644223:PAS_chr2-2_0258
uniprot id: C4R2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

644223:PAS chr4 0086
gene id: 644223:PAS_chr4_0086
uniprot id: C4R6T8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

644223:PAS chr1-3 0192
gene id: 644223:PAS_chr1-3_0192
uniprot id: C4QVI2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

644223:PAS chr2-2 0200
gene id: 644223:PAS_chr2-2_0200
uniprot id: C4R2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

644223:PAS chr1-4 0185
gene id: 644223:PAS_chr1-4_0185
uniprot id: C4QXP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

644223:PAS chr3 0223
gene id: 644223:PAS_chr3_0223
uniprot id: C4R3W9
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

644223:PAS chr3 1215
gene id: 644223:PAS_chr3_1215
uniprot id: C4R5F6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1169
gene id: 644223:PAS_chr3_1169
uniprot id: Q9P4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: cytoskeleton

644223:PAS chr2-2 0142
gene id: 644223:PAS_chr2-2_0142
uniprot id: C4R2Q9
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

644223:PAS chr2-1 0595
gene id: 644223:PAS_chr2-1_0595
uniprot id: C4R158
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

644223:PAS chr2-1 0755
gene id: 644223:PAS_chr2-1_0755
uniprot id: C4R1N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0020
gene id: 644223:PAS_chr4_0020
uniprot id: C4R6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

644223:PAS chr3 0726
gene id: 644223:PAS_chr3_0726
uniprot id: C4R5D9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

644223:PAS chr1-1 0270
gene id: 644223:PAS_chr1-1_0270
uniprot id: C4QWL8
names: Similarity
messages: Belongs to the EFG1 family.

644223:PAS chr2-2 0337
gene id: 644223:PAS_chr2-2_0337
uniprot id: C4R245
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

644223:PAS chr2-1 0528
gene id: 644223:PAS_chr2-1_0528
uniprot id: C4R0Y8
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

644223:PAS chr4 0669
gene id: 644223:PAS_chr4_0669
uniprot id: C4R8K3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

644223:PAS chr1-3 0101
gene id: 644223:PAS_chr1-3_0101
uniprot id: C4QV88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

644223:PAS chr3 0588
gene id: 644223:PAS_chr3_0588
uniprot id: C4R500
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

644223:PAS chr3 0574
gene id: 644223:PAS_chr3_0574
uniprot id: C4R4Y6
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0015
gene id: 644223:PAS_chr3_0015
uniprot id: C4R3B0
names: Subcellular Location Annotation
messages: Cell surface

644223:PAS chr1-1 0113
gene id: 644223:PAS_chr1-1_0113
uniprot id: C4QW52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

644223:PAS chr2-2 0326
gene id: 644223:PAS_chr2-2_0326
uniprot id: C4R256
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

644223:PAS chr1-4 0454
gene id: 644223:PAS_chr1-4_0454
uniprot id: C4QYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0263
gene id: 644223:PAS_chr4_0263
uniprot id: C4R7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

644223:PAS chr2-1 0073
gene id: 644223:PAS_chr2-1_0073
uniprot id: C4QZK0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0242
gene id: 644223:PAS_chr1-4_0242
uniprot id: C4QXV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

644223:PAS chr2-1 0343
gene id: 644223:PAS_chr2-1_0343
uniprot id: C4R0D8
names: Similarity
messages: Belongs to the group II decarboxylase family.

644223:PAS chr2-1 0274
gene id: 644223:PAS_chr2-1_0274
uniprot id: C4R064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

644223:PAS chr2-2 0124
gene id: 644223:PAS_chr2-2_0124
uniprot id: C4R2S8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0346
gene id: 644223:PAS_chr2-1_0346
uniprot id: C4R0E2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr4 0939
gene id: 644223:PAS_chr4_0939
uniprot id: C4R7E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

644223:PAS chr1-1 0315
gene id: 644223:PAS_chr1-1_0315
uniprot id: C4QWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

644223:PAS chr1-4 0095
gene id: 644223:PAS_chr1-4_0095
uniprot id: C4QXF2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

644223:PAS chr3 1197
gene id: 644223:PAS_chr3_1197
uniprot id: C4R4U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

644223:PAS chr1-1 0049
gene id: 644223:PAS_chr1-1_0049
uniprot id: C4QVY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

644223:PAS chr3 0989
gene id: 644223:PAS_chr3_0989
uniprot id: C4R665
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1236
gene id: 644223:PAS_chr3_1236
uniprot id: C4R5X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

644223:PAS chr1-4 0132
gene id: 644223:PAS_chr1-4_0132
uniprot id: C4QXI7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0260
gene id: 644223:PAS_chr2-2_0260
uniprot id: C4R2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

644223:PAS chr1-1 0008
gene id: 644223:PAS_chr1-1_0008
uniprot id: C4QVT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

644223:PAS chr1-1 0271
gene id: 644223:PAS_chr1-1_0271
uniprot id: C4QWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr4 0511
gene id: 644223:PAS_chr4_0511
uniprot id: C4R841
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

644223:PAS chr2-1 0675
gene id: 644223:PAS_chr2-1_0675
uniprot id: C4R1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0297
gene id: 644223:PAS_chr1-1_0297
uniprot id: C4QWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

644223:PAS chr1-3 0069
gene id: 644223:PAS_chr1-3_0069
uniprot id: C4QV51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

644223:PAS chr4 0521
gene id: 644223:PAS_chr4_0521
uniprot id: C4R851
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

644223:PAS chr4 0532
gene id: 644223:PAS_chr4_0532
uniprot id: C4R867
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0057
gene id: 644223:PAS_chr2-2_0057
uniprot id: C4R302
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

644223:PAS chr1-3 0046
gene id: 644223:PAS_chr1-3_0046
uniprot id: C4QV26
names: Similarity
messages: Belongs to the SH3BGR family.

644223:PAS chr2-1 0267
gene id: 644223:PAS_chr2-1_0267
uniprot id: C4R055
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

644223:PAS chr1-1 0197
gene id: 644223:PAS_chr1-1_0197
uniprot id: C4QWE0
names: Similarity
messages: Belongs to the AFG1 ATPase family.

644223:PAS chr1-4 0577
gene id: 644223:PAS_chr1-4_0577
uniprot id: C4QYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

644223:PAS chr2-1 0779
gene id: 644223:PAS_chr2-1_0779
uniprot id: C4R1R2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

644223:PAS chr2-2 0246
gene id: 644223:PAS_chr2-2_0246
uniprot id: C4R2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

644223:PAS chr2-1 0376
gene id: 644223:PAS_chr2-1_0376
uniprot id: C4R0H3
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

644223:PAS chr3 0657
gene id: 644223:PAS_chr3_0657
uniprot id: C4R568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

644223:PAS chr2-2 0164
gene id: 644223:PAS_chr2-2_0164
uniprot id: C4R2N6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

644223:PAS chr1-4 0530
gene id: 644223:PAS_chr1-4_0530
uniprot id: C4QYQ9
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

644223:PAS chr4 0087
gene id: 644223:PAS_chr4_0087
uniprot id: C4R6T9
names: Similarity
messages: Belongs to the RAD52 family.

644223:PAS chr2-1 0377
gene id: 644223:PAS_chr2-1_0377
uniprot id: C4R0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

644223:PAS chr1-4 0211
gene id: 644223:PAS_chr1-4_0211
uniprot id: C4QXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

644223:PAS chr3 1006
gene id: 644223:PAS_chr3_1006
uniprot id: C4R681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

644223:PAS chr2-2 0366
gene id: 644223:PAS_chr2-2_0366
uniprot id: C4R215
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

644223:PAS c121 0009
gene id: 644223:PAS_c121_0009
uniprot id: C4QZ48
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

644223:PAS chr2-1 0829
gene id: 644223:PAS_chr2-1_0829
uniprot id: C4R0C2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

644223:PAS chr1-3 0175
gene id: 644223:PAS_chr1-3_0175
uniprot id: C4QVG5
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

644223:PAS chr2-1 0560
gene id: 644223:PAS_chr2-1_0560
uniprot id: C4R120
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0570
gene id: 644223:PAS_chr2-1_0570
uniprot id: C4R132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

644223:PAS chr4 0465
gene id: 644223:PAS_chr4_0465
uniprot id: C4R7Z3
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFA/CMAS family.
messages: Catalyzes methylation of the sphingoid base component of glucosylceramides (GluCers) at the C9-position. Sphingolipid C9-methylation requires 4,8-desaturated ceramides as substrates. Glucosylceramides play important roles in growth, differentiation and pathogenicity. The methyl group at the C9-position distinguishes fungal glucosylceramides from those of plants and animals, and may thus play a role in host-pathogen interactions enabling the host to recognize the fungal attack and initiate specific defense responses.
messages: Membrane
messages: Produces only non-methylated glucosylceramides (PubMed:16339149). Shows no alteration of growth and no increase in the level of resistance to plant defensins MsDef1 and RsAFP2 (PubMed:19028992).

644223:PAS chr4 0889
gene id: 644223:PAS_chr4_0889
uniprot id: C4R984
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

644223:PAS chr3 0845
gene id: 644223:PAS_chr3_0845
uniprot id: C4R5R0
names: Similarity
messages: Belongs to the taffazin family.

644223:PAS chr1-3 0013
gene id: 644223:PAS_chr1-3_0013
uniprot id: C4QUZ5
names: Similarity
messages: Belongs to the isochorismatase family.

644223:PAS chr1-1 0423
gene id: 644223:PAS_chr1-1_0423
uniprot id: C4QX28
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0474
gene id: 644223:PAS_chr3_0474
uniprot id: C4R4N7
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

644223:PAS chr4 0320
gene id: 644223:PAS_chr4_0320
uniprot id: C4R7I8
names: Similarity
messages: Belongs to the EIS1 family.

644223:PAS chr4 0303
gene id: 644223:PAS_chr4_0303
uniprot id: C4R7G7
names: Subcellular Location Annotation
messages: Vacuole

644223:PAS chr2-1 0881
gene id: 644223:PAS_chr2-1_0881
uniprot id: C4R1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0687
gene id: 644223:PAS_chr2-1_0687
uniprot id: C4R1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

644223:PAS chr4 0986
gene id: 644223:PAS_chr4_0986
uniprot id: C4R8R9
names: Similarity
messages: Belongs to the PP2C family.

644223:PAS chr2-1 0313
gene id: 644223:PAS_chr2-1_0313
uniprot id: C4R0A4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr3 0079
gene id: 644223:PAS_chr3_0079
uniprot id: C4R3H6
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

644223:PAS chr1-4 0344
gene id: 644223:PAS_chr1-4_0344
uniprot id: C4QY64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

644223:PAS chr2-1 0008
gene id: 644223:PAS_chr2-1_0008
uniprot id: C4QZD3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr2-2 0481
gene id: 644223:PAS_chr2-2_0481
uniprot id: C4R2E2
names: Similarity
messages: Belongs to the asparaginase 1 family.

644223:PAS chr1-3 0252
gene id: 644223:PAS_chr1-3_0252
uniprot id: C4QVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

644223:PAS chr3 0170
gene id: 644223:PAS_chr3_0170
uniprot id: C4R3R2
names: Similarity
messages: Belongs to the AHA1 family.

644223:PAS chr2-1 0269
gene id: 644223:PAS_chr2-1_0269
uniprot id: C4R057
names: Similarity
messages: Belongs to the threonine synthase family.

644223:PAS chr1-4 0342
gene id: 644223:PAS_chr1-4_0342
uniprot id: C4QY62
names: Similarity
messages: Belongs to the phosducin family.

644223:PAS chr1-4 0006
gene id: 644223:PAS_chr1-4_0006
uniprot id: C4QX66
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr1-4 0633
gene id: 644223:PAS_chr1-4_0633
uniprot id: C4QZ20
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

644223:PAS chr3 0273
gene id: 644223:PAS_chr3_0273
uniprot id: C4R426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

644223:PAS chr4 0100
gene id: 644223:PAS_chr4_0100
uniprot id: C4R6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

644223:PAS chr2-2 0115
gene id: 644223:PAS_chr2-2_0115
uniprot id: C4R2T7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0190
gene id: 644223:PAS_chr2-1_0190
uniprot id: C4QZX4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0357
gene id: 644223:PAS_chr2-2_0357
uniprot id: C4R224
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

644223:PAS chr2-1 0514
gene id: 644223:PAS_chr2-1_0514
uniprot id: C4R0X2
names: Subcellular Location Annotation
messages: Peroxisome membrane

644223:PAS chr1-1 0481
gene id: 644223:PAS_chr1-1_0481
uniprot id: C4QWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0295
gene id: 644223:PAS_chr3_0295
uniprot id: C4R451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS chr2-1 0424
gene id: 644223:PAS_chr2-1_0424
uniprot id: C4R0M3
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

644223:PAS chr1-4 0499
gene id: 644223:PAS_chr1-4_0499
uniprot id: C4QYM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

644223:PAS chr3 0462
gene id: 644223:PAS_chr3_0462
uniprot id: C4R4M5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

644223:PAS chr2-1 0212
gene id: 644223:PAS_chr2-1_0212
uniprot id: C4QZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

644223:PAS chr1-4 0169
gene id: 644223:PAS_chr1-4_0169
uniprot id: C4QXM9
names: Similarity
messages: Belongs to the actin family.

644223:PAS chr4 0046
gene id: 644223:PAS_chr4_0046
uniprot id: C4R6P9
names: Similarity
messages: Belongs to the SUN family.

644223:PAS chr4 0742
gene id: 644223:PAS_chr4_0742
uniprot id: C4R8S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP9 family.
messages: RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
messages: nucleolus

644223:PAS chr1-1 0331
gene id: 644223:PAS_chr1-1_0331
uniprot id: C4QWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

644223:PAS chr2-2 0017
gene id: 644223:PAS_chr2-2_0017
uniprot id: C4R345
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

644223:PAS chr2-1 0183
gene id: 644223:PAS_chr2-1_0183
uniprot id: C4QZW7
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

644223:PAS chr1-3 0074
gene id: 644223:PAS_chr1-3_0074
uniprot id: C4QV56
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0902
gene id: 644223:PAS_chr4_0902
uniprot id: C4R997
names: Similarity
messages: Belongs to the PAF1 family.

644223:PAS chr1-1 0249
gene id: 644223:PAS_chr1-1_0249
uniprot id: C4QWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

644223:PAS chr3 0534
gene id: 644223:PAS_chr3_0534
uniprot id: C4R4U7
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr1-3 0281
gene id: 644223:PAS_chr1-3_0281
uniprot id: C4QVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

644223:PAS chr1-3 0178
gene id: 644223:PAS_chr1-3_0178
uniprot id: C4QVG8
names: Similarity
messages: Belongs to the TMA16 family.

644223:PAS chr3 0548
gene id: 644223:PAS_chr3_0548
uniprot id: C4R4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

644223:PAS chr2-1 0323
gene id: 644223:PAS_chr2-1_0323
uniprot id: C4R0B5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS chr4 0347
gene id: 644223:PAS_chr4_0347
uniprot id: C4R7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-2 0194
gene id: 644223:PAS_chr2-2_0194
uniprot id: C4R2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

644223:PAS chr1-1 0418
gene id: 644223:PAS_chr1-1_0418
uniprot id: C4QX23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

644223:PAS chr4 0562
gene id: 644223:PAS_chr4_0562
uniprot id: C4R897
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr4 0996
gene id: 644223:PAS_chr4_0996
uniprot id: C4R8Z5
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

644223:PAS chr4 0872
gene id: 644223:PAS_chr4_0872
uniprot id: C4R967
names: Similarity
messages: Belongs to the FYV7 family.

644223:PAS chr4 0416
gene id: 644223:PAS_chr4_0416
uniprot id: C4R7U0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr3 1076
gene id: 644223:PAS_chr3_1076
uniprot id: C4R6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr1-1 0293
gene id: 644223:PAS_chr1-1_0293
uniprot id: C4QWP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

644223:PAS chr2-2 0047
gene id: 644223:PAS_chr2-2_0047
uniprot id: C4R313
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0194
gene id: 644223:PAS_chr1-4_0194
uniprot id: C4QXQ4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0016
gene id: 644223:PAS_chr2-2_0016
uniprot id: C4R347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

644223:PAS chr2-1 0492
gene id: 644223:PAS_chr2-1_0492
uniprot id: C4R0U9
names: Similarity
messages: Belongs to the TCP11 family.

644223:PAS chr2-2 0407
gene id: 644223:PAS_chr2-2_0407
uniprot id: C4R1X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

644223:PAS chr4 0732
gene id: 644223:PAS_chr4_0732
uniprot id: C4R8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

644223:PAS chr2-2 0116
gene id: 644223:PAS_chr2-2_0116
uniprot id: C4R2T6
names: Similarity
messages: Belongs to the GST superfamily.

644223:PAS chr3 0797
gene id: 644223:PAS_chr3_0797
uniprot id: C4R5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

644223:PAS chr4 0623
gene id: 644223:PAS_chr4_0623
uniprot id: C4R8F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

644223:PAS chr1-4 0025
gene id: 644223:PAS_chr1-4_0025
uniprot id: C4QX86
names: Similarity
messages: Belongs to the frataxin family.

644223:PAS chr2-2 0094
gene id: 644223:PAS_chr2-2_0094
uniprot id: C4R2V9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0464
gene id: 644223:PAS_chr4_0464
uniprot id: C4R7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS chr4 0566
gene id: 644223:PAS_chr4_0566
uniprot id: C4R8A2
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

644223:PAS chr4 0607
gene id: 644223:PAS_chr4_0607
uniprot id: C4R8E2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0150
gene id: 644223:PAS_chr4_0150
uniprot id: C4R700
names: Similarity
messages: Belongs to the aspartokinase family.

644223:PAS chr2-1 0462
gene id: 644223:PAS_chr2-1_0462
uniprot id: C4R0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-2 0472
gene id: 644223:PAS_chr2-2_0472
uniprot id: C4R2J4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0040
gene id: 644223:PAS_chr2-2_0040
uniprot id: C4R321
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

644223:PAS chr1-4 0287
gene id: 644223:PAS_chr1-4_0287
uniprot id: C4QY01
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

644223:PAS chr4 0893
gene id: 644223:PAS_chr4_0893
uniprot id: C4R988
names: Similarity
messages: Belongs to the PP2C family.

644223:PAS chr1-1 0307
gene id: 644223:PAS_chr1-1_0307
uniprot id: C4QWR1
names: Similarity
messages: Belongs to the PPP phosphatase family.

644223:PAS chr3 0890
gene id: 644223:PAS_chr3_0890
uniprot id: C4R5W1
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

644223:PAS chr3 1128
gene id: 644223:PAS_chr3_1128
uniprot id: C4R361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

644223:PAS chr1-4 0338
gene id: 644223:PAS_chr1-4_0338
uniprot id: C4QY57
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

644223:PAS chr3 0238
gene id: 644223:PAS_chr3_0238
uniprot id: C4R3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

644223:PAS chr1-4 0114
gene id: 644223:PAS_chr1-4_0114
uniprot id: C4QXH0
names: Similarity
messages: Belongs to the UPF0507 family.

644223:PAS chr1-4 0145
gene id: 644223:PAS_chr1-4_0145
uniprot id: C4QXK1
names: Similarity
messages: Belongs to the pirin family.

644223:PAS chr2-2 0327
gene id: 644223:PAS_chr2-2_0327
uniprot id: C4R255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

644223:PAS chr2-1 0564
gene id: 644223:PAS_chr2-1_0564
uniprot id: C4R125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

644223:PAS chr4 0474
gene id: 644223:PAS_chr4_0474
uniprot id: C4R805
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

644223:PAS chr2-1 0435
gene id: 644223:PAS_chr2-1_0435
uniprot id: C4R0N9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

644223:PAS chr1-1 0183
gene id: 644223:PAS_chr1-1_0183
uniprot id: C4QWC5
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

644223:PAS chr4 0264
gene id: 644223:PAS_chr4_0264
uniprot id: C4R7C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

644223:PAS chr2-1 0606
gene id: 644223:PAS_chr2-1_0606
uniprot id: C4R169
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr3 1255
gene id: 644223:PAS_chr3_1255
uniprot id: C4R6H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

644223:PAS chr2-1 0239
gene id: 644223:PAS_chr2-1_0239
uniprot id: C4R026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

644223:PAS chr2-2 0350
gene id: 644223:PAS_chr2-2_0350
uniprot id: C4R231
names: Similarity
messages: Belongs to the syntaxin family.

644223:PAS chr3 0324
gene id: 644223:PAS_chr3_0324
uniprot id: C4R476
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

644223:PAS chr3 0853
gene id: 644223:PAS_chr3_0853
uniprot id: C4R5R8
names: Similarity
messages: Belongs to the peptidase C12 family.

644223:PAS chr1-3 0246
gene id: 644223:PAS_chr1-3_0246
uniprot id: C4QVN7
names: Similarity
messages: Belongs to the Luc7 family.

644223:PAS chr2-2 0243
gene id: 644223:PAS_chr2-2_0243
uniprot id: C4R2E8
names: Similarity
messages: Belongs to the exportin family.

644223:PAS chr4 0994
gene id: 644223:PAS_chr4_0994
uniprot id: C4R8Y2
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

644223:PAS chr3 0783
gene id: 644223:PAS_chr3_0783
uniprot id: C4R5K2
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

644223:PAS chr2-2 0043
gene id: 644223:PAS_chr2-2_0043
uniprot id: C4R317
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0494
gene id: 644223:PAS_chr2-1_0494
uniprot id: C4R0V1
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

644223:PAS chr1-3 0079
gene id: 644223:PAS_chr1-3_0079
uniprot id: C4QV62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETT1 family.
messages: Nucleus
messages: Required for correct translation termination and probably involved in regulation of hypoxic gene expression.

644223:PAS chr2-1 0309
gene id: 644223:PAS_chr2-1_0309
uniprot id: C4R0A0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0538
gene id: 644223:PAS_chr1-4_0538
uniprot id: C4QYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

644223:PAS chr1-3 0244
gene id: 644223:PAS_chr1-3_0244
uniprot id: C4QVN3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

644223:PAS chr1-3 0078
gene id: 644223:PAS_chr1-3_0078
uniprot id: C4QV61
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

644223:PAS chr4 0290
gene id: 644223:PAS_chr4_0290
uniprot id: C4R7F2
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

644223:PAS chr2-1 0452
gene id: 644223:PAS_chr2-1_0452
uniprot id: C4R0Q5
names: Similarity
messages: Belongs to the ADIP family.

644223:PAS chr2-1 0884
gene id: 644223:PAS_chr2-1_0884
uniprot id: C4R1N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

644223:PAS chr1-4 0134
gene id: 644223:PAS_chr1-4_0134
uniprot id: C4QXI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

644223:PAS chr3 0769
gene id: 644223:PAS_chr3_0769
uniprot id: C4R5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr4 0892
gene id: 644223:PAS_chr4_0892
uniprot id: C4R987
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0311
gene id: 644223:PAS_chr1-4_0311
uniprot id: C4QY29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

644223:PAS chr3 0992
gene id: 644223:PAS_chr3_0992
uniprot id: C4R668
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-1 0211
gene id: 644223:PAS_chr1-1_0211
uniprot id: C4QWF7
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

644223:PAS chr3 0354
gene id: 644223:PAS_chr3_0354
uniprot id: C4R4B0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

644223:PAS chr3 0038
gene id: 644223:PAS_chr3_0038
uniprot id: C4R3C9
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

644223:PAS chr4 0598
gene id: 644223:PAS_chr4_0598
uniprot id: C4R8D3
names: Similarity
messages: Belongs to the group II decarboxylase family.

644223:PAS chr4 0257
gene id: 644223:PAS_chr4_0257
uniprot id: C4R7B3
names: Similarity
messages: Belongs to the TCF25 family.

644223:PAS chr2-2 0084
gene id: 644223:PAS_chr2-2_0084
uniprot id: C4R2X1
names: Similarity
messages: Belongs to the alkaline phosphatase family.

644223:PAS chr4 0557
gene id: 644223:PAS_chr4_0557
uniprot id: C4R892
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers.

644223:PAS chr3 0565
gene id: 644223:PAS_chr3_0565
uniprot id: C4R4X7
names: Similarity
messages: Belongs to the HUS1 family.

644223:PAS chr1-3 0258
gene id: 644223:PAS_chr1-3_0258
uniprot id: C4QVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DDI1 family.
messages: Binds ubiquitin and polyubiquitinated proteins.
messages: Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control.

644223:PAS chr4 0213
gene id: 644223:PAS_chr4_0213
uniprot id: C4R764
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

644223:PAS chr2-1 0591
gene id: 644223:PAS_chr2-1_0591
uniprot id: C4R154
names: Similarity
messages: Belongs to the WD repeat coronin family.

644223:PAS chr1-3 0168
gene id: 644223:PAS_chr1-3_0168
uniprot id: C4QVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

644223:PAS chr2-1 0188
gene id: 644223:PAS_chr2-1_0188
uniprot id: C4QZX2
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr4 0813
gene id: 644223:PAS_chr4_0813
uniprot id: C4R909
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

644223:PAS chr1-4 0558
gene id: 644223:PAS_chr1-4_0558
uniprot id: C4QYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

644223:PAS chr4 0924
gene id: 644223:PAS_chr4_0924
uniprot id: C4R746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0684
gene id: 644223:PAS_chr4_0684
uniprot id: C4R8L9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

644223:PAS chr4 0967
gene id: 644223:PAS_chr4_0967
uniprot id: C4R804
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr3 1099
gene id: 644223:PAS_chr3_1099
uniprot id: C4R6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr1-4 0085
gene id: 644223:PAS_chr1-4_0085
uniprot id: C4QXE1
names: Similarity
messages: Belongs to the actin family.

644223:PAS chr2-1 0209
gene id: 644223:PAS_chr2-1_0209
uniprot id: C4QZZ3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

644223:PAS chr4 0806
gene id: 644223:PAS_chr4_0806
uniprot id: C4R901
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

644223:PAS chr4 0920
gene id: 644223:PAS_chr4_0920
uniprot id: C4R6X1
names: Similarity
messages: Belongs to the END3 family.

644223:PAS chr4 0327
gene id: 644223:PAS_chr4_0327
uniprot id: C4R7J5
names: Similarity
messages: Belongs to the GCN1 family.

644223:PAS chr1-4 0069
gene id: 644223:PAS_chr1-4_0069
uniprot id: C4QXC5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

644223:PAS chr4 0834
gene id: 644223:PAS_chr4_0834
uniprot id: C4R929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0197
gene id: 644223:PAS_chr2-1_0197
uniprot id: C4QZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

644223:PAS FragB 0053
gene id: 644223:PAS_FragB_0053
uniprot id: C4QZB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

644223:PAS chr1-4 0190
gene id: 644223:PAS_chr1-4_0190
uniprot id: C4QXQ0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0859
gene id: 644223:PAS_chr3_0859
uniprot id: C4R5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

644223:PAS chr2-1 0158
gene id: 644223:PAS_chr2-1_0158
uniprot id: C4QZU0
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

644223:PAS chr1-1 0484
gene id: 644223:PAS_chr1-1_0484
uniprot id: C4QWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0347
gene id: 644223:PAS_chr2-1_0347
uniprot id: C4R0E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

644223:PAS chr3 0184
gene id: 644223:PAS_chr3_0184
uniprot id: C4R3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

644223:PAS chr1-1 0439
gene id: 644223:PAS_chr1-1_0439
uniprot id: C4QX43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

644223:PAS chr1-3 0104
gene id: 644223:PAS_chr1-3_0104
uniprot id: C4QV90
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

644223:PAS chr4 0760
gene id: 644223:PAS_chr4_0760
uniprot id: C4R8U9
names: Similarity
messages: Belongs to the RRN3 family.

644223:PAS chr1-4 0313
gene id: 644223:PAS_chr1-4_0313
uniprot id: C4QY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-3 0127
gene id: 644223:PAS_chr1-3_0127
uniprot id: C4QVB4
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

644223:PAS chr3 0642
gene id: 644223:PAS_chr3_0642
uniprot id: C4R555
names: Similarity
messages: Belongs to the SF3A3 family.

644223:PAS chr1-1 0091
gene id: 644223:PAS_chr1-1_0091
uniprot id: C4QW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

644223:PAS FragB 0037
gene id: 644223:PAS_FragB_0037
uniprot id: C4QZ93
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

644223:PAS chr2-1 0834
gene id: 644223:PAS_chr2-1_0834
uniprot id: C4R0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0074
gene id: 644223:PAS_chr1-1_0074
uniprot id: C4QW11
names: Similarity
messages: Belongs to the small Tim family.

644223:PAS chr1-4 0518
gene id: 644223:PAS_chr1-4_0518
uniprot id: C4QYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

644223:PAS chr4 0638
gene id: 644223:PAS_chr4_0638
uniprot id: C4R8H3
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

644223:PAS chr2-1 0168
gene id: 644223:PAS_chr2-1_0168
uniprot id: C4QZV1
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

644223:PAS chr2-1 0817
gene id: 644223:PAS_chr2-1_0817
uniprot id: C4QZZ9
names: Similarity
messages: Belongs to the CBP3 family.

644223:PAS chr4 0690
gene id: 644223:PAS_chr4_0690
uniprot id: C4R8M6
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

644223:PAS chr3 0429
gene id: 644223:PAS_chr3_0429
uniprot id: C4R4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr3 0545
gene id: 644223:PAS_chr3_0545
uniprot id: C4R4V7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS FragB 0052
gene id: 644223:PAS_FragB_0052
uniprot id: C4QZB0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

644223:PAS chr2-1 0290
gene id: 644223:PAS_chr2-1_0290
uniprot id: C4R079
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

644223:PAS chr4 0117
gene id: 644223:PAS_chr4_0117
uniprot id: C4R6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

644223:PAS chr3 0541
gene id: 644223:PAS_chr3_0541
uniprot id: C4R4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

644223:PAS chr4 0836
gene id: 644223:PAS_chr4_0836
uniprot id: C4R931
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0172
gene id: 644223:PAS_chr3_0172
uniprot id: C4R3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

644223:PAS chr2-1 0038
gene id: 644223:PAS_chr2-1_0038
uniprot id: C4QZG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

644223:PAS chr3 1083
gene id: 644223:PAS_chr3_1083
uniprot id: C4R6G4
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

644223:PAS chr1-1 0203
gene id: 644223:PAS_chr1-1_0203
uniprot id: C4QWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

644223:PAS chr1-1 0013
gene id: 644223:PAS_chr1-1_0013
uniprot id: C4QVU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.
messages: Membrane

644223:PAS chr2-2 0482
gene id: 644223:PAS_chr2-2_0482
uniprot id: C4R2D7
names: Domain
names: Function
names: Similarity
messages: Belongs to the flocculin family. Highly divergent.
messages: Homophilic binding protein that enables kin discrimination in heterogeneous yeast populations by mediating homotypic cell-cell interactions during flocculation, a reversible and asexual process in which cells adhere to form aggregates (flocs).
messages: The Flo11 domain contains aromatic residues that form two hydrophobic bands on the surface of the protein that confer homophilic binding (PubMed:32286952). The hydrophobic bands are lined by stretches of acidic residues that may sensitise the protein to environmental pH (By similarity).

644223:PAS FragB 0049
gene id: 644223:PAS_FragB_0049
uniprot id: C4QZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS27 family.
messages: Endosome membrane
messages: Membrane

644223:PAS chr1-4 0497
gene id: 644223:PAS_chr1-4_0497
uniprot id: C4QYM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

644223:PAS chr4 0601
gene id: 644223:PAS_chr4_0601
uniprot id: C4R8D6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0111
gene id: 644223:PAS_chr4_0111
uniprot id: C4R6W1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0010
gene id: 644223:PAS_chr1-4_0010
uniprot id: C4QX70
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

644223:PAS chr3 0906
gene id: 644223:PAS_chr3_0906
uniprot id: C4R5X9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

644223:PAS chr4 0061
gene id: 644223:PAS_chr4_0061
uniprot id: C4R6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

644223:PAS chr2-1 0263
gene id: 644223:PAS_chr2-1_0263
uniprot id: C4R051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

644223:PAS chr1-3 0153
gene id: 644223:PAS_chr1-3_0153
uniprot id: C4QVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644223:PAS chr2-1 0296
gene id: 644223:PAS_chr2-1_0296
uniprot id: C4R086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0596
gene id: 644223:PAS_chr2-1_0596
uniprot id: C4R159
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG28 family.
messages: Cytoplasm
messages: Cytoplasmic vesicle membrane
messages: Expression is induced by methanol and glucose.
messages: Interacts with ATG35.
messages: Required for the autophagic degradation of peroxisomes called pexophagy, but not essential for general autophagy. Involved in resistance to elevated pH.
messages: Vacuole membrane

644223:PAS chr2-2 0356
gene id: 644223:PAS_chr2-2_0356
uniprot id: C4R225
names: Similarity
messages: Belongs to the Tom22 family.

644223:PAS chr4 0688
gene id: 644223:PAS_chr4_0688
uniprot id: C4R8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0027
gene id: 644223:PAS_chr1-1_0027
uniprot id: C4QVV8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0472
gene id: 644223:PAS_chr2-1_0472
uniprot id: C4R0S8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr2-1 0359
gene id: 644223:PAS_chr2-1_0359
uniprot id: C4R0F5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

644223:PAS chr3 0078
gene id: 644223:PAS_chr3_0078
uniprot id: C4R3H5
names: Similarity
messages: Belongs to the MEMO1 family.

644223:PAS chr4 0452
gene id: 644223:PAS_chr4_0452
uniprot id: C4R7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

644223:PAS chr4 0950
gene id: 644223:PAS_chr4_0950
uniprot id: C4R7N7
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-1 0475
gene id: 644223:PAS_chr1-1_0475
uniprot id: C4QW60
names: Similarity
messages: Belongs to the citrate synthase family.

644223:PAS chr2-2 0035
gene id: 644223:PAS_chr2-2_0035
uniprot id: C4R327
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

644223:PAS chr3 0060
gene id: 644223:PAS_chr3_0060
uniprot id: C4R3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

644223:PAS chr3 1234
gene id: 644223:PAS_chr3_1234
uniprot id: C4R5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

644223:PAS chr3 1140
gene id: 644223:PAS_chr3_1140
uniprot id: C4R375
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

644223:PAS chr1-1 0312
gene id: 644223:PAS_chr1-1_0312
uniprot id: C4QWR6
names: Similarity
messages: Belongs to the cullin family.

644223:PAS chr4 0982
gene id: 644223:PAS_chr4_0982
uniprot id: C4R8M3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

644223:PAS chr1-1 0276
gene id: 644223:PAS_chr1-1_0276
uniprot id: C4QWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

644223:PAS chr1-4 0597
gene id: 644223:PAS_chr1-4_0597
uniprot id: C4QYY2
names: Similarity
messages: Belongs to the RMD1/sif2 family.

644223:PAS chr4 0473
gene id: 644223:PAS_chr4_0473
uniprot id: C4R803
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0560
gene id: 644223:PAS_chr4_0560
uniprot id: C4R895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

644223:PAS chr4 0828
gene id: 644223:PAS_chr4_0828
uniprot id: C4R922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr4 0814
gene id: 644223:PAS_chr4_0814
uniprot id: C4R910
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

644223:PAS chr4 0815
gene id: 644223:PAS_chr4_0815
uniprot id: C4R911
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

644223:PAS chr4 0911
gene id: 644223:PAS_chr4_0911
uniprot id: C4R6L1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1218
gene id: 644223:PAS_chr3_1218
uniprot id: C4R5I3
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

644223:PAS chr2-1 0720
gene id: 644223:PAS_chr2-1_0720
uniprot id: C4R1J5
names: Similarity
messages: Belongs to the actin family.

644223:PAS chr3 1033
gene id: 644223:PAS_chr3_1033
uniprot id: C4R6B0
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

644223:PAS chr4 0231
gene id: 644223:PAS_chr4_0231
uniprot id: C4R787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

644223:PAS chr1-4 0267
gene id: 644223:PAS_chr1-4_0267
uniprot id: C4QXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

644223:PAS chr1-1 0003
gene id: 644223:PAS_chr1-1_0003
uniprot id: C4QVT0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0941
gene id: 644223:PAS_chr3_0941
uniprot id: C4R615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

644223:PAS chr3 1250
gene id: 644223:PAS_chr3_1250
uniprot id: C4R6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

644223:PAS chr3 0333
gene id: 644223:PAS_chr3_0333
uniprot id: C4R485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

644223:PAS chr3 0630
gene id: 644223:PAS_chr3_0630
uniprot id: C4R542
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

644223:PAS chr4 0220
gene id: 644223:PAS_chr4_0220
uniprot id: C4R773
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0287
gene id: 644223:PAS_chr1-1_0287
uniprot id: C4QWN9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0166
gene id: 644223:PAS_chr3_0166
uniprot id: C4R3Q6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr4 0243
gene id: 644223:PAS_chr4_0243
uniprot id: C4R797
names: Similarity
messages: Belongs to the TPA1 family.

644223:PAS chr1-4 0323
gene id: 644223:PAS_chr1-4_0323
uniprot id: C4QY41
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

644223:PAS chr1-4 0120
gene id: 644223:PAS_chr1-4_0120
uniprot id: C4QXH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

644223:PAS chr3 0967
gene id: 644223:PAS_chr3_0967
uniprot id: C4R643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr4 0751
gene id: 644223:PAS_chr4_0751
uniprot id: C4R8T8
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

644223:PAS chr4 0374
gene id: 644223:PAS_chr4_0374
uniprot id: C4R7P3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

644223:PAS chr4 0621
gene id: 644223:PAS_chr4_0621
uniprot id: C4R8F6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

644223:PAS chr1-3 0123
gene id: 644223:PAS_chr1-3_0123
uniprot id: C4QVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
messages: nucleolus

644223:PAS chr4 0226
gene id: 644223:PAS_chr4_0226
uniprot id: C4R780
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

644223:PAS chr2-1 0505
gene id: 644223:PAS_chr2-1_0505
uniprot id: C4R0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

644223:PAS chr2-2 0187
gene id: 644223:PAS_chr2-2_0187
uniprot id: C4R2K9
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr2-2 0135
gene id: 644223:PAS_chr2-2_0135
uniprot id: C4R2R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

644223:PAS chr3 0267
gene id: 644223:PAS_chr3_0267
uniprot id: C4R420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

644223:PAS chr2-1 0853
gene id: 644223:PAS_chr2-1_0853
uniprot id: C4R0W4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr1-4 0280
gene id: 644223:PAS_chr1-4_0280
uniprot id: C4QXZ2
names: Similarity
messages: Belongs to the PPP phosphatase family.

644223:PAS chr2-1 0812
gene id: 644223:PAS_chr2-1_0812
uniprot id: C4QZQ5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

644223:PAS chr1-1 0194
gene id: 644223:PAS_chr1-1_0194
uniprot id: C4QWD7
names: Similarity
messages: Belongs to the peptidase M28 family.

644223:PAS chr3 0815
gene id: 644223:PAS_chr3_0815
uniprot id: C4R5N2
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

644223:PAS chr2-2 0360
gene id: 644223:PAS_chr2-2_0360
uniprot id: C4R221
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

644223:PAS chr4 0778
gene id: 644223:PAS_chr4_0778
uniprot id: C4R8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-1 0164
gene id: 644223:PAS_chr1-1_0164
uniprot id: C4QWA6
names: Similarity
messages: Belongs to the FAH family.

644223:PAS chr1-3 0066
gene id: 644223:PAS_chr1-3_0066
uniprot id: C4QV48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

644223:PAS chr2-1 0769
gene id: 644223:PAS_chr2-1_0769
uniprot id: C4R1P9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

644223:PAS chr3 0775
gene id: 644223:PAS_chr3_0775
uniprot id: C4R5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

644223:PAS chr1-4 0243
gene id: 644223:PAS_chr1-4_0243
uniprot id: C4QXV5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

644223:PAS chr1-4 0421
gene id: 644223:PAS_chr1-4_0421
uniprot id: C4QYE7
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

644223:PAS chr2-1 0565
gene id: 644223:PAS_chr2-1_0565
uniprot id: C4R127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Mitochondrion inner membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

644223:PAS FragD 0016
gene id: 644223:PAS_FragD_0016
uniprot id: C4R9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

644223:PAS chr1-3 0272
gene id: 644223:PAS_chr1-3_0272
uniprot id: C4QVR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

644223:PAS chr4 0614
gene id: 644223:PAS_chr4_0614
uniprot id: C4R8E9
names: Similarity
messages: Belongs to the CCZ1 family.

644223:PAS chr2-1 0156
gene id: 644223:PAS_chr2-1_0156
uniprot id: C4QZT8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

644223:PAS chr4 0348
gene id: 644223:PAS_chr4_0348
uniprot id: C4R7L7
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

644223:PAS chr1-1 0313
gene id: 644223:PAS_chr1-1_0313
uniprot id: C4QWR7
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

644223:PAS chr1-4 0150
gene id: 644223:PAS_chr1-4_0150
uniprot id: C4QXK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

644223:PAS chr1-1 0319
gene id: 644223:PAS_chr1-1_0319
uniprot id: C4QWS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

644223:PAS chr2-1 0163
gene id: 644223:PAS_chr2-1_0163
uniprot id: C4QZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

644223:PAS chr3 0367
gene id: 644223:PAS_chr3_0367
uniprot id: C4R4C5
names: Similarity
messages: Belongs to the Cdt1 family.

644223:PAS chr2-1 0103
gene id: 644223:PAS_chr2-1_0103
uniprot id: C4QZN1
names: Similarity
messages: Belongs to the histidine acid phosphatase family.

644223:PAS chr1-4 0422
gene id: 644223:PAS_chr1-4_0422
uniprot id: C4QYE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

644223:PAS chr3 0563
gene id: 644223:PAS_chr3_0563
uniprot id: C4R4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus

644223:PAS chr1-4 0299
gene id: 644223:PAS_chr1-4_0299
uniprot id: C4QY16
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

644223:PAS chr2-1 0626
gene id: 644223:PAS_chr2-1_0626
uniprot id: C4R194
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

644223:PAS chr4 0197
gene id: 644223:PAS_chr4_0197
uniprot id: C4R748
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

644223:PAS chr2-1 0086
gene id: 644223:PAS_chr2-1_0086
uniprot id: C4QZL3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

644223:PAS chr3 0595
gene id: 644223:PAS_chr3_0595
uniprot id: C4R506
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0662
gene id: 644223:PAS_chr4_0662
uniprot id: C4R8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

644223:PAS chr1-4 0257
gene id: 644223:PAS_chr1-4_0257
uniprot id: C4QXW8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0985
gene id: 644223:PAS_chr3_0985
uniprot id: C4R662
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr4 0018
gene id: 644223:PAS_chr4_0018
uniprot id: C4R6L9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

644223:PAS c121 0007
gene id: 644223:PAS_c121_0007
uniprot id: C4QZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

644223:PAS chr3 0043
gene id: 644223:PAS_chr3_0043
uniprot id: C4R3D4
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

644223:PAS chr3 0403
gene id: 644223:PAS_chr3_0403
uniprot id: C4R4G6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

644223:PAS chr4 0427
gene id: 644223:PAS_chr4_0427
uniprot id: C4R7V4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0341
gene id: 644223:PAS_chr1-1_0341
uniprot id: C4QWU6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0292
gene id: 644223:PAS_chr1-1_0292
uniprot id: C4QWP5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

644223:PAS chr3 0935
gene id: 644223:PAS_chr3_0935
uniprot id: C4R610
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr4 0792
gene id: 644223:PAS_chr4_0792
uniprot id: C4R8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

644223:PAS chr3 0991
gene id: 644223:PAS_chr3_0991
uniprot id: C4R667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

644223:PAS chr3 0593
gene id: 644223:PAS_chr3_0593
uniprot id: C4R504
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

644223:PAS chr1-4 0618
gene id: 644223:PAS_chr1-4_0618
uniprot id: C4QZ03
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr4 0232
gene id: 644223:PAS_chr4_0232
uniprot id: C4R788
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

644223:PAS chr3 0969
gene id: 644223:PAS_chr3_0969
uniprot id: C4R647
names: Similarity
messages: Belongs to the RNase Z family.

644223:PAS chr1-4 0534
gene id: 644223:PAS_chr1-4_0534
uniprot id: C4QYR3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr3 0867
gene id: 644223:PAS_chr3_0867
uniprot id: C4R5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

644223:PAS chr3 0643
gene id: 644223:PAS_chr3_0643
uniprot id: C4R556
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0684
gene id: 644223:PAS_chr1-4_0684
uniprot id: C4QYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM9 family.
messages: Mitochondrion

644223:PAS chr4 0341
gene id: 644223:PAS_chr4_0341
uniprot id: C4R7K9
names: Similarity
messages: Belongs to the DapA family.

644223:PAS chr4 0974
gene id: 644223:PAS_chr4_0974
uniprot id: C4R862
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

644223:PAS chr4 0692
gene id: 644223:PAS_chr4_0692
uniprot id: C4R8M8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

644223:PAS chr4 0227
gene id: 644223:PAS_chr4_0227
uniprot id: C4R781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

644223:PAS chr3 0979
gene id: 644223:PAS_chr3_0979
uniprot id: C4R657
names: Similarity
messages: Belongs to the peptidase S14 family.

644223:PAS chr3 0501
gene id: 644223:PAS_chr3_0501
uniprot id: C4R4R3
names: Similarity
messages: Belongs to the ATG101 family.

644223:PAS chr1-1 0191
gene id: 644223:PAS_chr1-1_0191
uniprot id: C4QWD4
names: Similarity
messages: Belongs to the ATPase delta chain family.

644223:PAS chr1-4 0163
gene id: 644223:PAS_chr1-4_0163
uniprot id: C4QXM0
names: Similarity
messages: Belongs to the GroES chaperonin family.

644223:PAS chr4 0149
gene id: 644223:PAS_chr4_0149
uniprot id: C4R6Z9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

644223:PAS chr4 0074
gene id: 644223:PAS_chr4_0074
uniprot id: C4R6S5
names: Similarity
messages: Belongs to the VPS26 family.

644223:PAS chr3 0741
gene id: 644223:PAS_chr3_0741
uniprot id: C4R5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

644223:PAS chr3 0282
gene id: 644223:PAS_chr3_0282
uniprot id: C4R436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644223:PAS chr3 0968
gene id: 644223:PAS_chr3_0968
uniprot id: C4R646
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0322
gene id: 644223:PAS_chr3_0322
uniprot id: C4R475
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

644223:PAS chr1-1 0018
gene id: 644223:PAS_chr1-1_0018
uniprot id: C4QVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

644223:PAS c131 0004
gene id: 644223:PAS_c131_0004
uniprot id: C4R382
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

644223:PAS chr3 0868
gene id: 644223:PAS_chr3_0868
uniprot id: C4R5T8
names: Similarity
messages: Belongs to the FBPase class 1 family.

644223:PAS chr2-2 0240
gene id: 644223:PAS_chr2-2_0240
uniprot id: C4R2F2
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

644223:PAS chr1-4 0148
gene id: 644223:PAS_chr1-4_0148
uniprot id: C4QXK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

644223:PAS chr1-1 0378
gene id: 644223:PAS_chr1-1_0378
uniprot id: C4QWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

644223:PAS chr2-2 0091
gene id: 644223:PAS_chr2-2_0091
uniprot id: C4R2W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

644223:PAS chr1-3 0140
gene id: 644223:PAS_chr1-3_0140
uniprot id: C4QVC6
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

644223:PAS chr2-2 0100
gene id: 644223:PAS_chr2-2_0100
uniprot id: C4R2V3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

644223:PAS chr2-1 0522
gene id: 644223:PAS_chr2-1_0522
uniprot id: C4R0Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

644223:PAS chr1-1 0030
gene id: 644223:PAS_chr1-1_0030
uniprot id: C4QVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

644223:PAS chr1-1 0032
gene id: 644223:PAS_chr1-1_0032
uniprot id: C4QVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 1131
gene id: 644223:PAS_chr3_1131
uniprot id: C4R365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

644223:PAS FragB 0020
gene id: 644223:PAS_FragB_0020
uniprot id: C4QZ76
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

644223:PAS chr1-3 0124
gene id: 644223:PAS_chr1-3_0124
uniprot id: C4QVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

644223:PAS chr2-1 0393
gene id: 644223:PAS_chr2-1_0393
uniprot id: C4R0J0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

644223:PAS chr3 0363
gene id: 644223:PAS_chr3_0363
uniprot id: C4R4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

644223:PAS chr3 0561
gene id: 644223:PAS_chr3_0561
uniprot id: C4R4X3
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

644223:PAS chr3 0339
gene id: 644223:PAS_chr3_0339
uniprot id: C4R491
names: Similarity
messages: Belongs to the TIP41 family.

644223:PAS chr1-1 0184
gene id: 644223:PAS_chr1-1_0184
uniprot id: C4QWC7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

644223:PAS c121 0011
gene id: 644223:PAS_c121_0011
uniprot id: C4QZ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

644223:PAS chr2-1 0087
gene id: 644223:PAS_chr2-1_0087
uniprot id: C4QZL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

644223:PAS chr3 0814
gene id: 644223:PAS_chr3_0814
uniprot id: C4R5N1
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0029
gene id: 644223:PAS_chr2-1_0029
uniprot id: C4QZF5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0120
gene id: 644223:PAS_chr3_0120
uniprot id: C4R3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-3 0062
gene id: 644223:PAS_chr1-3_0062
uniprot id: C4QV44
names: Similarity
messages: Belongs to the YOS1 family.

644223:PAS chr3 0874
gene id: 644223:PAS_chr3_0874
uniprot id: C4R5U5
names: Subcellular Location Annotation
messages: Peroxisome membrane

644223:PAS chr2-2 0369
gene id: 644223:PAS_chr2-2_0369
uniprot id: C4R212
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0765
gene id: 644223:PAS_chr4_0765
uniprot id: C4R8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

644223:PAS chr2-1 0721
gene id: 644223:PAS_chr2-1_0721
uniprot id: C4R1J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

644223:PAS chr4 0483
gene id: 644223:PAS_chr4_0483
uniprot id: C4R815
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

644223:PAS chr3 0644
gene id: 644223:PAS_chr3_0644
uniprot id: C4R557
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr2-1 0075
gene id: 644223:PAS_chr2-1_0075
uniprot id: C4QZK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

644223:PAS chr1-4 0592
gene id: 644223:PAS_chr1-4_0592
uniprot id: C4QYX7
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

644223:PAS chr2-1 0049
gene id: 644223:PAS_chr2-1_0049
uniprot id: C4QZH5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0819
gene id: 644223:PAS_chr4_0819
uniprot id: C4R915
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

644223:PAS chr1-4 0210
gene id: 644223:PAS_chr1-4_0210
uniprot id: C4QXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

644223:PAS chr1-3 0110
gene id: 644223:PAS_chr1-3_0110
uniprot id: C4QV97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

644223:PAS chr1-4 0140
gene id: 644223:PAS_chr1-4_0140
uniprot id: C4QXJ5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0270
gene id: 644223:PAS_chr2-1_0270
uniprot id: C4R058
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

644223:PAS chr1-3 0105
gene id: 644223:PAS_chr1-3_0105
uniprot id: C4QV92
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

644223:PAS chr1-4 0292
gene id: 644223:PAS_chr1-4_0292
uniprot id: C4QY07
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

644223:PAS chr1-4 0282
gene id: 644223:PAS_chr1-4_0282
uniprot id: C4QXZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

644223:PAS chr3 1227
gene id: 644223:PAS_chr3_1227
uniprot id: C4R5R9
names: Similarity
messages: Belongs to the glutaredoxin family.

644223:PAS chr4 0368
gene id: 644223:PAS_chr4_0368
uniprot id: C4R7N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

644223:PAS chr2-1 0402
gene id: 644223:PAS_chr2-1_0402
uniprot id: Q92448
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (By similarity). Involved in the modulation of glucose-induced microautophagy of peroxisomes independent of its ability to metabolize glucose intermediates.
messages: Cytoplasm
messages: Heterododecamer of 4 alpha, 4 beta and 4 gamma chains. The gamma chain bridges the N-terminal halves of the alpha and beta subunits (By similarity).

644223:PAS chr1-1 0081
gene id: 644223:PAS_chr1-1_0081
uniprot id: C4QW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-2 0423
gene id: 644223:PAS_chr2-2_0423
uniprot id: C4R1W2
names: Similarity
messages: Belongs to the oxoprolinase family.

644223:PAS chr4 0313
gene id: 644223:PAS_chr4_0313
uniprot id: C4R7H9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

644223:PAS chr3 0684
gene id: 644223:PAS_chr3_0684
uniprot id: C4R597
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

644223:PAS chr4 0152
gene id: 644223:PAS_chr4_0152
uniprot id: C4R702
names: Domain
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GMC oxidoreductase family.
messages: Homooctamer.
messages: Induced by methanol. Subject to strong carbon catabolite repression (By similarity).
messages: Minor isoform of alcohol oxidase, which catalyzes the oxidation of methanol to formaldehyde and hydrogen peroxide, the first step in the methanol utilization pathway of methylotrophic yeasts.
messages: Peroxisome matrix
messages: The C-terminal peroxisomal targeting signal (PTS) is essential for the efficient targeting and import of AOX into peroxisomes via the PTS1 pathway.

644223:PAS chr2-2 0415
gene id: 644223:PAS_chr2-2_0415
uniprot id: C4R1W9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

644223:PAS chr4 0451
gene id: 644223:PAS_chr4_0451
uniprot id: C4R7X9
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT family.
messages: Beta-mannosyltransferase involved in cell wall biosynthesis. Involved in the beta-mannosylation of outer chains of N-glycans.
messages: Impaired expression of beta-mannose epitopes and decreases alpha-mannosidase resistant glycans.
messages: Membrane

644223:PAS chr3 0062
gene id: 644223:PAS_chr3_0062
uniprot id: C4R3F6
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

644223:PAS chr1-1 0337
gene id: 644223:PAS_chr1-1_0337
uniprot id: C4QWU1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

644223:PAS chr1-1 0095
gene id: 644223:PAS_chr1-1_0095
uniprot id: C4QW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

644223:PAS chr1-4 0668
gene id: 644223:PAS_chr1-4_0668
uniprot id: C4QY14
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

644223:PAS chr1-3 0202
gene id: 644223:PAS_chr1-3_0202
uniprot id: C4QVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

644223:PAS chr2-1 0169
gene id: 644223:PAS_chr2-1_0169
uniprot id: C4QZV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

644223:PAS chr1-1 0296
gene id: 644223:PAS_chr1-1_0296
uniprot id: C4QWP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

644223:PAS chr2-1 0590
gene id: 644223:PAS_chr2-1_0590
uniprot id: C4R153
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr3 0300
gene id: 644223:PAS_chr3_0300
uniprot id: C4R455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

644223:PAS chr1-3 0044
gene id: 644223:PAS_chr1-3_0044
uniprot id: C4QV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

644223:PAS chr1-4 0489
gene id: 644223:PAS_chr1-4_0489
uniprot id: C4QYL9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

644223:PAS chr2-1 0634
gene id: 644223:PAS_chr2-1_0634
uniprot id: C4R1A3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

644223:PAS chr2-1 0363
gene id: 644223:PAS_chr2-1_0363
uniprot id: C4R0G0
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6A family.

644223:PAS chr1-1 0433
gene id: 644223:PAS_chr1-1_0433
uniprot id: C4QX37
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

644223:PAS chr4 0610
gene id: 644223:PAS_chr4_0610
uniprot id: C4R8E5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0120
gene id: 644223:PAS_chr2-1_0120
uniprot id: C4QZQ0
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

644223:PAS chr3 1173
gene id: 644223:PAS_chr3_1173
uniprot id: C4R419
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

644223:PAS chr1-3 0048
gene id: 644223:PAS_chr1-3_0048
uniprot id: C4QV28
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr4 0084
gene id: 644223:PAS_chr4_0084
uniprot id: C4R6T5
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

644223:PAS chr2-2 0295
gene id: 644223:PAS_chr2-2_0295
uniprot id: C4R289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

644223:PAS chr3 0787
gene id: 644223:PAS_chr3_0787
uniprot id: C4R5K5
names: Similarity
messages: Belongs to the MNN1/MNT family.

644223:PAS chr4 0843
gene id: 644223:PAS_chr4_0843
uniprot id: C4R937
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr4 0673
gene id: 644223:PAS_chr4_0673
uniprot id: C4R8K7
names: Similarity
messages: Belongs to the TACO1 family.

644223:PAS chr4 0513
gene id: 644223:PAS_chr4_0513
uniprot id: C4R843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

644223:PAS chr3 0908
gene id: 644223:PAS_chr3_0908
uniprot id: C4R5Y1
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

644223:PAS chr3 0623
gene id: 644223:PAS_chr3_0623
uniprot id: C4R533
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

644223:PAS chr2-1 0251
gene id: 644223:PAS_chr2-1_0251
uniprot id: C4R039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-4 0041
gene id: 644223:PAS_chr1-4_0041
uniprot id: C4QX99
names: Similarity
messages: Belongs to the multicopper oxidase family.

644223:PAS chr1-4 0474
gene id: 644223:PAS_chr1-4_0474
uniprot id: C4QYK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTC6 family.
messages: May be involved in telomere capping.
messages: Membrane

644223:PAS chr3 0215
gene id: 644223:PAS_chr3_0215
uniprot id: C4R3V8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr2-2 0263
gene id: 644223:PAS_chr2-2_0263
uniprot id: C4R2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr3 0622
gene id: 644223:PAS_chr3_0622
uniprot id: C4R532
names: Similarity
messages: Belongs to the TRL1 family.

644223:PAS chr2-2 0076
gene id: 644223:PAS_chr2-2_0076
uniprot id: C4R2Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

644223:PAS chr2-1 0796
gene id: 644223:PAS_chr2-1_0796
uniprot id: C4R1T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

644223:PAS chr1-4 0002
gene id: 644223:PAS_chr1-4_0002
uniprot id: C4QX62
names: Similarity
messages: Belongs to the UPF0538 family.

644223:PAS chr2-1 0308
gene id: 644223:PAS_chr2-1_0308
uniprot id: C4R099
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

644223:PAS chr3 1174
gene id: 644223:PAS_chr3_1174
uniprot id: C4QXU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

644223:PAS chr2-1 0379
gene id: 644223:PAS_chr2-1_0379
uniprot id: C4R0H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

644223:PAS chr2-2 0300
gene id: 644223:PAS_chr2-2_0300
uniprot id: C4R283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

644223:PAS chr3 0167
gene id: 644223:PAS_chr3_0167
uniprot id: C4R3Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

644223:PAS chr2-1 0767
gene id: 644223:PAS_chr2-1_0767
uniprot id: C4R1P7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

644223:PAS chr1-3 0070
gene id: 644223:PAS_chr1-3_0070
uniprot id: C4QV52
names: Similarity
messages: Belongs to the PPase family.

644223:PAS chr1-4 0399
gene id: 644223:PAS_chr1-4_0399
uniprot id: C4QYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

644223:PAS chr1-3 0264
gene id: 644223:PAS_chr1-3_0264
uniprot id: C4QVQ4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr2-2 0461
gene id: 644223:PAS_chr2-2_0461
uniprot id: C4R2U2
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

644223:PAS chr4 0109
gene id: 644223:PAS_chr4_0109
uniprot id: C4R6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

644223:PAS chr1-3 0287
gene id: 644223:PAS_chr1-3_0287
uniprot id: C4QVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).

644223:PAS chr2-1 0655
gene id: 644223:PAS_chr2-1_0655
uniprot id: C4R1C6
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr3 0826
gene id: 644223:PAS_chr3_0826
uniprot id: C4R5P4
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

644223:PAS c131 0001
gene id: 644223:PAS_c131_0001
uniprot id: C4R379
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP2 subfamily.

644223:PAS chr1-1 0300
gene id: 644223:PAS_chr1-1_0300
uniprot id: C4QWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr3 0489
gene id: 644223:PAS_chr3_0489
uniprot id: C4R4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

644223:PAS chr3 0649
gene id: 644223:PAS_chr3_0649
uniprot id: C4R561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644223:PAS chr1-1 0417
gene id: 644223:PAS_chr1-1_0417
uniprot id: C4QX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

644223:PAS chr3 1162
gene id: 644223:PAS_chr3_1162
uniprot id: C4R3V9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr1-1 0435
gene id: 644223:PAS_chr1-1_0435
uniprot id: C4QX39
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr4 0842
gene id: 644223:PAS_chr4_0842
uniprot id: C4R936
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

644223:PAS chr4 0488
gene id: 644223:PAS_chr4_0488
uniprot id: C4R819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0368
gene id: 644223:PAS_chr1-4_0368
uniprot id: C4QY88
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

644223:PAS chr1-3 0014
gene id: 644223:PAS_chr1-3_0014
uniprot id: C4QUZ6
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr4 0309
gene id: 644223:PAS_chr4_0309
uniprot id: C4R7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

644223:PAS chr1-1 0241
gene id: 644223:PAS_chr1-1_0241
uniprot id: C4QWI8
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

644223:PAS chr2-1 0482
gene id: 644223:PAS_chr2-1_0482
uniprot id: C4R0T8
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

644223:PAS chr3 0397
gene id: 644223:PAS_chr3_0397
uniprot id: C4R4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr3 0587
gene id: 644223:PAS_chr3_0587
uniprot id: C4R4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

644223:PAS chr1-3 0163
gene id: 644223:PAS_chr1-3_0163
uniprot id: C4QVF2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0366
gene id: 644223:PAS_chr1-1_0366
uniprot id: C4QWX0
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

644223:PAS chr1-4 0020
gene id: 644223:PAS_chr1-4_0020
uniprot id: C4QX81
names: Similarity
messages: Belongs to the APC1 family.

644223:PAS chr1-3 0080
gene id: 644223:PAS_chr1-3_0080
uniprot id: C4QV63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

644223:PAS chr1-1 0419
gene id: 644223:PAS_chr1-1_0419
uniprot id: C4QX24
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

644223:PAS chr1-4 0082
gene id: 644223:PAS_chr1-4_0082
uniprot id: C4QXD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

644223:PAS chr4 0065
gene id: 644223:PAS_chr4_0065
uniprot id: C4R6R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

644223:PAS chr1-1 0286
gene id: 644223:PAS_chr1-1_0286
uniprot id: C4QWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

644223:PAS chr4 0712
gene id: 644223:PAS_chr4_0712
uniprot id: Q6DNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG3 family.
messages: Endoplasmic reticulum membrane

644223:PAS chr4 0306
gene id: 644223:PAS_chr4_0306
uniprot id: C4R7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

644223:PAS chr4 0044
gene id: 644223:PAS_chr4_0044
uniprot id: C4R6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

644223:PAS chr1-3 0221
gene id: 644223:PAS_chr1-3_0221
uniprot id: C4QVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

644223:PAS chr1-1 0252
gene id: 644223:PAS_chr1-1_0252
uniprot id: C4QWJ9
names: Similarity
messages: Belongs to the FUN14 family.

644223:PAS FragD 0003
gene id: 644223:PAS_FragD_0003
uniprot id: C4R9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

644223:PAS chr3 0959
gene id: 644223:PAS_chr3_0959
uniprot id: C4R634
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

644223:PAS chr3 0182
gene id: 644223:PAS_chr3_0182
uniprot id: C4R3S6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0119
gene id: 644223:PAS_chr1-3_0119
uniprot id: C4QVA6
names: Similarity
messages: Belongs to the yippee family.

644223:PAS chr1-4 0070
gene id: 644223:PAS_chr1-4_0070
uniprot id: C4QXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

644223:PAS chr3 0678
gene id: 644223:PAS_chr3_0678
uniprot id: C4R591
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
messages: Nucleus

644223:PAS chr4 0335
gene id: 644223:PAS_chr4_0335
uniprot id: C4R7K2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

644223:PAS chr2-1 0094
gene id: 644223:PAS_chr2-1_0094
uniprot id: C4QZM1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

644223:PAS chr4 0229
gene id: 644223:PAS_chr4_0229
uniprot id: C4R784
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

644223:PAS chr4 0668
gene id: 644223:PAS_chr4_0668
uniprot id: C4R8K2
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

644223:PAS chr4 0439
gene id: 644223:PAS_chr4_0439
uniprot id: C4R7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644223:PAS chr1-3 0261
gene id: 644223:PAS_chr1-3_0261
uniprot id: C4QVQ2
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr3 0596
gene id: 644223:PAS_chr3_0596
uniprot id: C4R507
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

644223:PAS chr1-3 0236
gene id: 644223:PAS_chr1-3_0236
uniprot id: C4QVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

644223:PAS chr2-1 0537
gene id: 644223:PAS_chr2-1_0537
uniprot id: C4R0Z6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

644223:PAS chr1-4 0316
gene id: 644223:PAS_chr1-4_0316
uniprot id: C4QY34
names: Similarity
messages: Belongs to the NEMF family.

644223:PAS chr1-3 0194
gene id: 644223:PAS_chr1-3_0194
uniprot id: C4QVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

644223:PAS chr2-1 0107
gene id: 644223:PAS_chr2-1_0107
uniprot id: C4QZN6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr2-1 0115
gene id: 644223:PAS_chr2-1_0115
uniprot id: C4QZP5
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

644223:PAS chr3 0857
gene id: 644223:PAS_chr3_0857
uniprot id: C4R5S4
names: Similarity
messages: Belongs to the FMO family.

644223:PAS chr1-3 0118
gene id: 644223:PAS_chr1-3_0118
uniprot id: C4QVA5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

644223:PAS chr1-1 0217
gene id: 644223:PAS_chr1-1_0217
uniprot id: C4QWG4
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

644223:PAS chr2-2 0306
gene id: 644223:PAS_chr2-2_0306
uniprot id: C4R276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

644223:PAS chr4 0533
gene id: 644223:PAS_chr4_0533
uniprot id: C4R868
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

644223:PAS chr3 0579
gene id: 644223:PAS_chr3_0579
uniprot id: C4R4Z1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

644223:PAS chr2-2 0050
gene id: 644223:PAS_chr2-2_0050
uniprot id: C4R310
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1024
gene id: 644223:PAS_chr3_1024
uniprot id: C4R6A0
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

644223:PAS chr2-2 0170
gene id: 644223:PAS_chr2-2_0170
uniprot id: C4R2M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

644223:PAS chr4 0140
gene id: 644223:PAS_chr4_0140
uniprot id: C4R6Z1
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0234
gene id: 644223:PAS_chr4_0234
uniprot id: C4R790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

644223:PAS chr3 1041
gene id: 644223:PAS_chr3_1041
uniprot id: C4R6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

644223:PAS chr1-4 0550
gene id: 644223:PAS_chr1-4_0550
uniprot id: C4QYT2
names: Similarity
messages: Belongs to the SEC3 family.

644223:PAS chr2-1 0854
gene id: 644223:PAS_chr2-1_0854
uniprot id: C4R0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-2 0315
gene id: 644223:PAS_chr2-2_0315
uniprot id: C4R267
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

644223:PAS chr1-1 0407
gene id: 644223:PAS_chr1-1_0407
uniprot id: C4QX11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RGI1 family.
messages: Cell membrane
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

644223:PAS chr2-2 0058
gene id: 644223:PAS_chr2-2_0058
uniprot id: C4R301
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

644223:PAS chr4 0107
gene id: 644223:PAS_chr4_0107
uniprot id: C4QWG6
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

644223:PAS chr3 0976
gene id: 644223:PAS_chr3_0976
uniprot id: C4R654
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

644223:PAS chr1-1 0050
gene id: 644223:PAS_chr1-1_0050
uniprot id: C4QVY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

644223:PAS FragB 0009
gene id: 644223:PAS_FragB_0009
uniprot id: C4QZ66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

644223:PAS chr3 0766
gene id: 644223:PAS_chr3_0766
uniprot id: C4R5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

644223:PAS chr2-2 0484
gene id: 644223:PAS_chr2-2_0484
uniprot id: C4R2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr4 0095
gene id: 644223:PAS_chr4_0095
uniprot id: C4R6U7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0027
gene id: 644223:PAS_chr4_0027
uniprot id: C4R6M8
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.

644223:PAS chr4 0091
gene id: 644223:PAS_chr4_0091
uniprot id: C4R6U3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

644223:PAS chr4 0957
gene id: 644223:PAS_chr4_0957
uniprot id: C4R7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr2-2 0197
gene id: 644223:PAS_chr2-2_0197
uniprot id: C4R2J9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

644223:PAS chr3 0612
gene id: 644223:PAS_chr3_0612
uniprot id: C4R522
names: Similarity
messages: Belongs to the importin alpha family.

644223:PAS chr3 0119
gene id: 644223:PAS_chr3_0119
uniprot id: C4R3L3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

644223:PAS chr4 0864
gene id: 644223:PAS_chr4_0864
uniprot id: C4R959
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

644223:PAS chr4 0715
gene id: 644223:PAS_chr4_0715
uniprot id: C4R8Q1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
messages: This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

644223:PAS chr2-1 0627
gene id: 644223:PAS_chr2-1_0627
uniprot id: C4R195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

644223:PAS chr4 0214
gene id: 644223:PAS_chr4_0214
uniprot id: C4R765
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

644223:PAS chr4 0577
gene id: 644223:PAS_chr4_0577
uniprot id: C4R8B1
names: Similarity
messages: Belongs to the DapA family.

644223:PAS chr2-2 0349
gene id: 644223:PAS_chr2-2_0349
uniprot id: C4R232
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

644223:PAS chr2-1 0033
gene id: 644223:PAS_chr2-1_0033
uniprot id: C4QZF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

644223:PAS chr4 0571
gene id: 644223:PAS_chr4_0571
uniprot id: C4R8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr3 0245
gene id: 644223:PAS_chr3_0245
uniprot id: C4R3Z6
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1056
gene id: 644223:PAS_chr3_1056
uniprot id: C4R6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr2-2 0273
gene id: 644223:PAS_chr2-2_0273
uniprot id: C4R2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

644223:PAS chr3 0468
gene id: 644223:PAS_chr3_0468
uniprot id: C4R4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

644223:PAS chr3 0756
gene id: 644223:PAS_chr3_0756
uniprot id: C4R5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0302
gene id: 644223:PAS_chr1-1_0302
uniprot id: C4QWQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

644223:PAS chr2-1 0126
gene id: 644223:PAS_chr2-1_0126
uniprot id: C4QZQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

644223:PAS chr2-1 0688
gene id: 644223:PAS_chr2-1_0688
uniprot id: C4R1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

644223:PAS chr3 0748
gene id: 644223:PAS_chr3_0748
uniprot id: C4R5G2
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

644223:PAS chr3 0851
gene id: 644223:PAS_chr3_0851
uniprot id: C4R5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

644223:PAS chr3 0620
gene id: 644223:PAS_chr3_0620
uniprot id: C4R531
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

644223:PAS chr3 0933
gene id: 644223:PAS_chr3_0933
uniprot id: C4R608
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr2-2 0077
gene id: 644223:PAS_chr2-2_0077
uniprot id: C4R2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

644223:PAS chr3 0516
gene id: 644223:PAS_chr3_0516
uniprot id: C4R4S9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0036
gene id: 644223:PAS_chr1-1_0036
uniprot id: C4QVX1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS chr3 0028
gene id: 644223:PAS_chr3_0028
uniprot id: C4R3C2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1134
gene id: 644223:PAS_chr3_1134
uniprot id: C4R368
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

644223:PAS chr4 0293
gene id: 644223:PAS_chr4_0293
uniprot id: C4R7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr4 0799
gene id: 644223:PAS_chr4_0799
uniprot id: C4R8Z3
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

644223:PAS chr4 0811
gene id: 644223:PAS_chr4_0811
uniprot id: C4R907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

644223:PAS chr3 0274
gene id: 644223:PAS_chr3_0274
uniprot id: C4R427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-2 0373
gene id: 644223:PAS_chr2-2_0373
uniprot id: C4R208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

644223:PAS chr1-4 0430
gene id: 644223:PAS_chr1-4_0430
uniprot id: C4QYF7
names: Similarity
messages: Belongs to the peptidase C14B family.

644223:PAS chr4 0478
gene id: 644223:PAS_chr4_0478
uniprot id: C4R810
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

644223:PAS chr1-1 0068
gene id: 644223:PAS_chr1-1_0068
uniprot id: C4QW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LCL3 family.
messages: Membrane
messages: Mitochondrion

644223:PAS chr4 0640
gene id: 644223:PAS_chr4_0640
uniprot id: C4R8H4
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

644223:PAS chr2-2 0446
gene id: 644223:PAS_chr2-2_0446
uniprot id: C4R1T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

644223:PAS chr3 1114
gene id: 644223:PAS_chr3_1114
uniprot id: C4R6J5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

644223:PAS chr1-1 0102
gene id: 644223:PAS_chr1-1_0102
uniprot id: C4QW41
names: Subcellular Location Annotation
messages: Chromosome

644223:PAS chr2-1 0770
gene id: 644223:PAS_chr2-1_0770
uniprot id: C4R1Q0
names: Similarity
messages: Belongs to the uridine kinase family.

644223:PAS chr1-1 0399
gene id: 644223:PAS_chr1-1_0399
uniprot id: C4QX03
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr3 1119
gene id: 644223:PAS_chr3_1119
uniprot id: C4R6K0
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

644223:PAS chr3 1200
gene id: 644223:PAS_chr3_1200
uniprot id: C4R4Z8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

644223:PAS chr1-3 0090
gene id: 644223:PAS_chr1-3_0090
uniprot id: C4QV74
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

644223:PAS chr1-4 0490
gene id: 644223:PAS_chr1-4_0490
uniprot id: C4QYM0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

644223:PAS chr2-1 0851
gene id: 644223:PAS_chr2-1_0851
uniprot id: C4R0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-2 0279
gene id: 644223:PAS_chr2-2_0279
uniprot id: C4R2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

644223:PAS chr1-1 0238
gene id: 644223:PAS_chr1-1_0238
uniprot id: C4QWI4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0140
gene id: 644223:PAS_chr2-1_0140
uniprot id: C4QZS3
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

644223:PAS chr2-2 0114
gene id: 644223:PAS_chr2-2_0114
uniprot id: C4R2T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr1-1 0140
gene id: 644223:PAS_chr1-1_0140
uniprot id: C4QW81
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

644223:PAS chr3 0006
gene id: 644223:PAS_chr3_0006
uniprot id: C4R3A2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr4 0191
gene id: 644223:PAS_chr4_0191
uniprot id: C4R741
names: Similarity
messages: Belongs to the malate synthase family.

644223:PAS chr2-2 0401
gene id: 644223:PAS_chr2-2_0401
uniprot id: C4R1Y4
names: Similarity
messages: Belongs to the cytidylyltransferase family.

644223:PAS chr3 0537
gene id: 644223:PAS_chr3_0537
uniprot id: C4R4V1
names: Similarity
messages: Belongs to the Tim44 family.

644223:PAS chr2-1 0380
gene id: 644223:PAS_chr2-1_0380
uniprot id: C4R0H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr3 0210
gene id: 644223:PAS_chr3_0210
uniprot id: C4R3V3
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

644223:PAS chr4 0292
gene id: 644223:PAS_chr4_0292
uniprot id: C4R7F4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

644223:PAS chr1-4 0445
gene id: 644223:PAS_chr1-4_0445
uniprot id: C4QYH3
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

644223:PAS chr1-4 0621
gene id: 644223:PAS_chr1-4_0621
uniprot id: C4QZ07
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0703
gene id: 644223:PAS_chr4_0703
uniprot id: C4R8P0
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

644223:PAS c121 0014
gene id: 644223:PAS_c121_0014
uniprot id: C4QZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

644223:PAS chr4 0415
gene id: 644223:PAS_chr4_0415
uniprot id: C4R7T9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

644223:PAS chr3 0710
gene id: 644223:PAS_chr3_0710
uniprot id: C4R5C5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr1-1 0330
gene id: 644223:PAS_chr1-1_0330
uniprot id: C4QWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0810
gene id: 644223:PAS_chr3_0810
uniprot id: C4R5M7
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

644223:PAS chr3 0110
gene id: 644223:PAS_chr3_0110
uniprot id: C4R3K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

644223:PAS chr1-4 0561
gene id: 644223:PAS_chr1-4_0561
uniprot id: C4QYU3
names: Similarity
messages: Belongs to the hexokinase family.

644223:PAS chr2-1 0831
gene id: 644223:PAS_chr2-1_0831
uniprot id: C4R0F9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

644223:PAS chr3 1107
gene id: 644223:PAS_chr3_1107
uniprot id: C4R6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

644223:PAS chr1-1 0064
gene id: 644223:PAS_chr1-1_0064
uniprot id: C4QVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

644223:PAS chr2-2 0261
gene id: 644223:PAS_chr2-2_0261
uniprot id: C4R2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

644223:PAS chr4 0713
gene id: 644223:PAS_chr4_0713
uniprot id: C4R8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr2-1 0670
gene id: 644223:PAS_chr2-1_0670
uniprot id: C4R1E2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0454
gene id: 644223:PAS_chr2-1_0454
uniprot id: C4R0Q7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

644223:PAS chr4 0594
gene id: 644223:PAS_chr4_0594
uniprot id: C4R8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM23 family.
messages: Mitochondrion

644223:PAS chr3 0095
gene id: 644223:PAS_chr3_0095
uniprot id: C4R3I9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

644223:PAS chr1-4 0354
gene id: 644223:PAS_chr1-4_0354
uniprot id: C4QY73
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

644223:PAS chr1-1 0086
gene id: 644223:PAS_chr1-1_0086
uniprot id: C4QW23
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0454
gene id: 644223:PAS_chr1-1_0454
uniprot id: C4QX57
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0363
gene id: 644223:PAS_chr2-2_0363
uniprot id: C4R219
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

644223:PAS chr2-1 0364
gene id: 644223:PAS_chr2-1_0364
uniprot id: C4R0G1
names: Similarity
messages: Belongs to the MT-A70-like family.

644223:PAS chr3 0411
gene id: 644223:PAS_chr3_0411
uniprot id: C4R4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr4 0998
gene id: 644223:PAS_chr4_0998
uniprot id: C4R927
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0635
gene id: 644223:PAS_chr3_0635
uniprot id: C4R548
names: Similarity
messages: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.

644223:PAS chr3 0739
gene id: 644223:PAS_chr3_0739
uniprot id: C4R5F3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

644223:PAS chr3 0896
gene id: 644223:PAS_chr3_0896
uniprot id: C4R5W7
names: Similarity
messages: Belongs to the peptidase S9B family.

644223:PAS chr2-2 0328
gene id: 644223:PAS_chr2-2_0328
uniprot id: C4R254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

644223:PAS chr1-4 0182
gene id: 644223:PAS_chr1-4_0182
uniprot id: C4QXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

644223:PAS chr4 0881
gene id: 644223:PAS_chr4_0881
uniprot id: C4R977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

644223:PAS c121 0002
gene id: 644223:PAS_c121_0002
uniprot id: C4QZ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

644223:PAS chr3 0178
gene id: 644223:PAS_chr3_0178
uniprot id: C4R3S2
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

644223:PAS chr4 0005
gene id: 644223:PAS_chr4_0005
uniprot id: C4R6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

644223:PAS chr1-4 0391
gene id: 644223:PAS_chr1-4_0391
uniprot id: C4QYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

644223:PAS chr1-4 0371
gene id: 644223:PAS_chr1-4_0371
uniprot id: C4QY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0092
gene id: 644223:PAS_chr4_0092
uniprot id: C4R6U4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0768
gene id: 644223:PAS_chr2-1_0768
uniprot id: C4R1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

644223:PAS chr3 0777
gene id: 644223:PAS_chr3_0777
uniprot id: C4R5J3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0125
gene id: 644223:PAS_chr3_0125
uniprot id: C4R3L9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0618
gene id: 644223:PAS_chr4_0618
uniprot id: C4R8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

644223:PAS c131 0016
gene id: 644223:PAS_c131_0016
uniprot id: C4R394
names: Similarity
messages: Belongs to the PP2C family.

644223:PAS FragB 0008
gene id: 644223:PAS_FragB_0008
uniprot id: C4QZ65
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

644223:PAS chr2-1 0184
gene id: 644223:PAS_chr2-1_0184
uniprot id: C4QZW8
names: Similarity
messages: Belongs to the VPS37 family.

644223:PAS chr1-4 0080
gene id: 644223:PAS_chr1-4_0080
uniprot id: C4QXD6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

644223:PAS chr4 0604
gene id: 644223:PAS_chr4_0604
uniprot id: C4R8D9
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr3 0194
gene id: 644223:PAS_chr3_0194
uniprot id: C4R3T7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

644223:PAS chr2-2 0143
gene id: 644223:PAS_chr2-2_0143
uniprot id: C4R2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

644223:PAS chr4 0990
gene id: 644223:PAS_chr4_0990
uniprot id: C4R8V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

644223:PAS chr2-1 0378
gene id: 644223:PAS_chr2-1_0378
uniprot id: C4R0H6
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0512
gene id: 644223:PAS_chr4_0512
uniprot id: C4R842
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

644223:PAS chr2-1 0523
gene id: 644223:PAS_chr2-1_0523
uniprot id: C4R0Y4
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

644223:PAS chr1-4 0601
gene id: 644223:PAS_chr1-4_0601
uniprot id: C4QYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

644223:PAS chr4 0228
gene id: 644223:PAS_chr4_0228
uniprot id: C4R783
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

644223:PAS chr1-1 0236
gene id: 644223:PAS_chr1-1_0236
uniprot id: C4QWI2
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

644223:PAS chr1-4 0304
gene id: 644223:PAS_chr1-4_0304
uniprot id: C4QY22
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

644223:PAS chr2-1 0265
gene id: 644223:PAS_chr2-1_0265
uniprot id: C4R053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

644223:PAS chr2-2 0271
gene id: 644223:PAS_chr2-2_0271
uniprot id: C4R2B9
names: Similarity
messages: Belongs to the PGA52 family.

644223:PAS chr1-1 0158
gene id: 644223:PAS_chr1-1_0158
uniprot id: C4QW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

644223:PAS chr2-2 0266
gene id: 644223:PAS_chr2-2_0266
uniprot id: C4R2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0456
gene id: 644223:PAS_chr2-1_0456
uniprot id: C4R0Q9
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

644223:PAS chr2-1 0178
gene id: 644223:PAS_chr2-1_0178
uniprot id: C4QZW2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

644223:PAS chr2-1 0459
gene id: 644223:PAS_chr2-1_0459
uniprot id: C4R0R2
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

644223:PAS chr3 0433
gene id: 644223:PAS_chr3_0433
uniprot id: C4R4J7
names: Similarity
messages: Belongs to the CWC26 family.

644223:PAS chr3 0236
gene id: 644223:PAS_chr3_0236
uniprot id: C4R3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

644223:PAS chr2-1 0793
gene id: 644223:PAS_chr2-1_0793
uniprot id: C4R1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

644223:PAS chr3 1249
gene id: 644223:PAS_chr3_1249
uniprot id: C4R6E5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

644223:PAS chr3 0934
gene id: 644223:PAS_chr3_0934
uniprot id: C4R609
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr4 0946
gene id: 644223:PAS_chr4_0946
uniprot id: C4R7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

644223:PAS chr1-1 0424
gene id: 644223:PAS_chr1-1_0424
uniprot id: C4QX29
names: Similarity
messages: Belongs to the UPP synthase family.

644223:PAS chr1-3 0029
gene id: 644223:PAS_chr1-3_0029
uniprot id: C4QV11
names: Similarity
messages: Belongs to the TrpF family.

644223:PAS chr3 0467
gene id: 644223:PAS_chr3_0467
uniprot id: C4R4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

644223:PAS chr2-1 0761
gene id: 644223:PAS_chr2-1_0761
uniprot id: C4R1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

644223:PAS chr3 0584
gene id: 644223:PAS_chr3_0584
uniprot id: C4R4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

644223:PAS chr3 0490
gene id: 644223:PAS_chr3_0490
uniprot id: C4R4Q3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1025
gene id: 644223:PAS_chr3_1025
uniprot id: C4R6A2
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

644223:PAS chr2-2 0322
gene id: 644223:PAS_chr2-2_0322
uniprot id: C4R260
names: Cofactor
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.

644223:PAS chr2-1 0697
gene id: 644223:PAS_chr2-1_0697
uniprot id: C4R1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

644223:PAS chr4 0085
gene id: 644223:PAS_chr4_0085
uniprot id: C4R6T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr1-1 0201
gene id: 644223:PAS_chr1-1_0201
uniprot id: C4QWE5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

644223:PAS chr3 0608
gene id: 644223:PAS_chr3_0608
uniprot id: C4R519
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

644223:PAS chr1-1 0174
gene id: 644223:PAS_chr1-1_0174
uniprot id: C4QWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

644223:PAS chr4 0608
gene id: 644223:PAS_chr4_0608
uniprot id: C4R8E3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0160
gene id: 644223:PAS_chr4_0160
uniprot id: C4R710
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

644223:PAS chr3 1203
gene id: 644223:PAS_chr3_1203
uniprot id: C4R538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

644223:PAS chr2-2 0480
gene id: 644223:PAS_chr2-2_0480
uniprot id: C4R2E7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

644223:PAS chr1-4 0187
gene id: 644223:PAS_chr1-4_0187
uniprot id: C4QXP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).
messages: Endoplasmic reticulum membrane
messages: The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates.

644223:PAS chr3 1047
gene id: 644223:PAS_chr3_1047
uniprot id: C4R6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

644223:PAS chr4 0240
gene id: 644223:PAS_chr4_0240
uniprot id: C4R794
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0142
gene id: 644223:PAS_chr1-3_0142
uniprot id: C4QVC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

644223:PAS chr4 0780
gene id: 644223:PAS_chr4_0780
uniprot id: C4R8X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

644223:PAS chr3 0069
gene id: 644223:PAS_chr3_0069
uniprot id: C4R3G3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

644223:PAS chr1-3 0232
gene id: 644223:PAS_chr1-3_0232
uniprot id: C4QVM1
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

644223:PAS chr3 1095
gene id: 644223:PAS_chr3_1095
uniprot id: C4R6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

644223:PAS chr4 0113
gene id: 644223:PAS_chr4_0113
uniprot id: C4R6W3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr1-4 0433
gene id: 644223:PAS_chr1-4_0433
uniprot id: C4QYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

644223:PAS chr1-1 0163
gene id: 644223:PAS_chr1-1_0163
uniprot id: C4QWA5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

644223:PAS chr3 0954
gene id: 644223:PAS_chr3_0954
uniprot id: C4R629
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

644223:PAS chr3 1121
gene id: 644223:PAS_chr3_1121
uniprot id: C4R6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

644223:PAS chr2-2 0241
gene id: 644223:PAS_chr2-2_0241
uniprot id: C4R2F1
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

644223:PAS chr1-4 0064
gene id: 644223:PAS_chr1-4_0064
uniprot id: C4QXC1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr2-2 0031
gene id: 644223:PAS_chr2-2_0031
uniprot id: C4R331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

644223:PAS chr1-1 0405
gene id: 644223:PAS_chr1-1_0405
uniprot id: C4QX09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

644223:PAS chr4 0953
gene id: 644223:PAS_chr4_0953
uniprot id: C4R7P9
names: Similarity
messages: Belongs to the cytochrome b5 family.

644223:PAS chr1-3 0054
gene id: 644223:PAS_chr1-3_0054
uniprot id: C4QV36
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

644223:PAS chr2-2 0210
gene id: 644223:PAS_chr2-2_0210
uniprot id: C4R2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

644223:PAS chr1-3 0305
gene id: 644223:PAS_chr1-3_0305
uniprot id: C4QVJ3
names: Similarity
messages: Belongs to the IMPACT family.

644223:PAS chr2-1 0386
gene id: 644223:PAS_chr2-1_0386
uniprot id: C4R0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

644223:PAS chr3 0822
gene id: 644223:PAS_chr3_0822
uniprot id: C4R5N8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0211
gene id: 644223:PAS_chr4_0211
uniprot id: C4R762
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

644223:PAS chr1-1 0143
gene id: 644223:PAS_chr1-1_0143
uniprot id: C4QW84
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

644223:PAS chr2-1 0629
gene id: 644223:PAS_chr2-1_0629
uniprot id: C4R198
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0307
gene id: 644223:PAS_chr3_0307
uniprot id: C4R461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0845
gene id: 644223:PAS_chr4_0845
uniprot id: C4R939
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

644223:PAS chr3 0512
gene id: 644223:PAS_chr3_0512
uniprot id: C4R4S5
names: Similarity
messages: Belongs to the lipin family.

644223:PAS chr2-1 0143
gene id: 644223:PAS_chr2-1_0143
uniprot id: C4QZS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

644223:PAS chr3 0248
gene id: 644223:PAS_chr3_0248
uniprot id: C4R3Z9
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0181
gene id: 644223:PAS_chr1-4_0181
uniprot id: C4QXP1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

644223:PAS chr1-1 0242
gene id: 644223:PAS_chr1-1_0242
uniprot id: C4QWI9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

644223:PAS chr2-1 0727
gene id: 644223:PAS_chr2-1_0727
uniprot id: C4R1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-2 0071
gene id: 644223:PAS_chr2-2_0071
uniprot id: C4R2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

644223:PAS chr3 0315
gene id: 644223:PAS_chr3_0315
uniprot id: C4R468
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1246
gene id: 644223:PAS_chr3_1246
uniprot id: C4R695
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

644223:PAS chr4 0561
gene id: 644223:PAS_chr4_0561
uniprot id: C4R896
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

644223:PAS chr3 0818
gene id: 644223:PAS_chr3_0818
uniprot id: C4R5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

644223:PAS chr1-4 0017
gene id: 644223:PAS_chr1-4_0017
uniprot id: C4QX78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endopolyphosphatase PPN1 family.
messages: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
messages: Membrane
messages: Vacuole membrane

644223:PAS FragB 0044
gene id: 644223:PAS_FragB_0044
uniprot id: C4QZA3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0483
gene id: 644223:PAS_chr3_0483
uniprot id: C4R4P6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0725
gene id: 644223:PAS_chr2-1_0725
uniprot id: C4R1K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS chr3 0217
gene id: 644223:PAS_chr3_0217
uniprot id: C4R3W2
names: Similarity
messages: Belongs to the PPP phosphatase family.

644223:PAS chr2-2 0152
gene id: 644223:PAS_chr2-2_0152
uniprot id: C4R2Q0
names: Similarity
messages: Belongs to the MUB1/samB family.

644223:PAS chr1-4 0359
gene id: 644223:PAS_chr1-4_0359
uniprot id: C4QY79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

644223:PAS chr4 0729
gene id: 644223:PAS_chr4_0729
uniprot id: C4R8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

644223:PAS chr1-1 0111
gene id: 644223:PAS_chr1-1_0111
uniprot id: C4QW50
names: Similarity
messages: Belongs to the peptidase M24B family.

644223:PAS chr1-4 0694
gene id: 644223:PAS_chr1-4_0694
uniprot id: C4QXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

644223:PAS chr1-3 0181
gene id: 644223:PAS_chr1-3_0181
uniprot id: C4QVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

644223:PAS chr3 0824
gene id: 644223:PAS_chr3_0824
uniprot id: C4R5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

644223:PAS chr4 0968
gene id: 644223:PAS_chr4_0968
uniprot id: C4R807
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

644223:PAS chr4 0720
gene id: 644223:PAS_chr4_0720
uniprot id: C4R8Q6
names: Similarity
messages: Belongs to the MBF1 family.

644223:PAS chr2-1 0123
gene id: 644223:PAS_chr2-1_0123
uniprot id: C4QZQ3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr1-4 0008
gene id: 644223:PAS_chr1-4_0008
uniprot id: C4QX68
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-4 0640
gene id: 644223:PAS_chr1-4_0640
uniprot id: C4QZ27
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-1 0474
gene id: 644223:PAS_chr1-1_0474
uniprot id: C4QW57
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

644223:PAS chr3 0473
gene id: 644223:PAS_chr3_0473
uniprot id: C4R4N6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

644223:PAS chr3 0458
gene id: 644223:PAS_chr3_0458
uniprot id: C4R4M1
names: Similarity
messages: Belongs to the actin family.

644223:PAS chr2-1 0788
gene id: 644223:PAS_chr2-1_0788
uniprot id: C4R1S2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

644223:PAS chr4 0354
gene id: 644223:PAS_chr4_0354
uniprot id: C4R7M3
names: Subcellular Location Annotation
messages: Nucleus membrane

644223:PAS chr1-1 0284
gene id: 644223:PAS_chr1-1_0284
uniprot id: C4QWN5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0598
gene id: 644223:PAS_chr1-4_0598
uniprot id: C4QYY3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.

644223:PAS chr4 0063
gene id: 644223:PAS_chr4_0063
uniprot id: C4R6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

644223:PAS chr2-1 0304
gene id: 644223:PAS_chr2-1_0304
uniprot id: C4R095
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

644223:PAS chr2-2 0387
gene id: 644223:PAS_chr2-2_0387
uniprot id: C4R1Z5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

644223:PAS chr4 0430
gene id: 644223:PAS_chr4_0430
uniprot id: C4R7V6
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

644223:PAS chr3 0913
gene id: 644223:PAS_chr3_0913
uniprot id: C4R5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

644223:PAS chr3 0914
gene id: 644223:PAS_chr3_0914
uniprot id: C4R5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

644223:PAS chr2-2 0309
gene id: 644223:PAS_chr2-2_0309
uniprot id: C4R273
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

644223:PAS chr4 0482
gene id: 644223:PAS_chr4_0482
uniprot id: C4R814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

644223:PAS chr1-1 0144
gene id: 644223:PAS_chr1-1_0144
uniprot id: C4QW85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

644223:PAS chr2-2 0319
gene id: 644223:PAS_chr2-2_0319
uniprot id: C4R263
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

644223:PAS chr1-4 0447
gene id: 644223:PAS_chr1-4_0447
uniprot id: C4QYH5
names: Similarity
messages: Belongs to the hexokinase family.

644223:PAS chr4 0350
gene id: 644223:PAS_chr4_0350
uniprot id: C4R7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

644223:PAS chr2-1 0845
gene id: 644223:PAS_chr2-1_0845
uniprot id: C4R0N6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

644223:PAS chr3 0749
gene id: 644223:PAS_chr3_0749
uniprot id: C4R5G3
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0551
gene id: 644223:PAS_chr3_0551
uniprot id: C4R4W4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0056
gene id: 644223:PAS_chr2-2_0056
uniprot id: C4R303
names: Similarity
messages: Belongs to the peptidase M67C family.

644223:PAS chr2-1 0124
gene id: 644223:PAS_chr2-1_0124
uniprot id: C4QZQ6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

644223:PAS chr1-4 0426
gene id: 644223:PAS_chr1-4_0426
uniprot id: C4QYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

644223:PAS chr3 1045
gene id: 644223:PAS_chr3_1045
uniprot id: C4R6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

644223:PAS chr2-2 0311
gene id: 644223:PAS_chr2-2_0311
uniprot id: C4R271
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

644223:PAS chr3 0576
gene id: 644223:PAS_chr3_0576
uniprot id: C4R4Y8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

644223:PAS chr1-4 0090
gene id: 644223:PAS_chr1-4_0090
uniprot id: C4QXE6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0367
gene id: 644223:PAS_chr1-1_0367
uniprot id: C4QWX1
names: Similarity
messages: Belongs to the UFD1 family.

644223:PAS chr3 0268
gene id: 644223:PAS_chr3_0268
uniprot id: C4R421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

644223:PAS chr2-1 0439
gene id: 644223:PAS_chr2-1_0439
uniprot id: C4R0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

644223:PAS chr4 0667
gene id: 644223:PAS_chr4_0667
uniprot id: C4R8K0
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-4 0074
gene id: 644223:PAS_chr1-4_0074
uniprot id: C4QXD0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

644223:PAS chr2-1 0597
gene id: 644223:PAS_chr2-1_0597
uniprot id: C4R160
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0191
gene id: 644223:PAS_chr2-1_0191
uniprot id: C4QZX5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

644223:PAS chr2-2 0427
gene id: 644223:PAS_chr2-2_0427
uniprot id: C4R1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0144
gene id: 644223:PAS_chr2-1_0144
uniprot id: C4QZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 6 family.
messages: Nucleus

644223:PAS chr1-4 0557
gene id: 644223:PAS_chr1-4_0557
uniprot id: C4QYT9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

644223:PAS chr1-1 0379
gene id: 644223:PAS_chr1-1_0379
uniprot id: C4QWY4
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr3 0564
gene id: 644223:PAS_chr3_0564
uniprot id: C4R4X6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

644223:PAS chr2-1 0480
gene id: 644223:PAS_chr2-1_0480
uniprot id: C4R0T6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0724
gene id: 644223:PAS_chr2-1_0724
uniprot id: C4R1J9
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

644223:PAS chr4 0812
gene id: 644223:PAS_chr4_0812
uniprot id: C4R908
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

644223:PAS chr1-3 0226
gene id: 644223:PAS_chr1-3_0226
uniprot id: C4QVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

644223:PAS chr3 0888
gene id: 644223:PAS_chr3_0888
uniprot id: C4R5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr3 1100
gene id: 644223:PAS_chr3_1100
uniprot id: C4R6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

644223:PAS chr4 0776
gene id: 644223:PAS_chr4_0776
uniprot id: C4R8W6
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0955
gene id: 644223:PAS_chr3_0955
uniprot id: C4R630
names: Similarity
messages: Belongs to the band 7/mec-2 family.

644223:PAS chr4 0503
gene id: 644223:PAS_chr4_0503
uniprot id: C4R834
names: Similarity
messages: Belongs to the peptidase C48 family.

644223:PAS chr3 0456
gene id: 644223:PAS_chr3_0456
uniprot id: C4R4L7
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

644223:PAS chr4 0987
gene id: 644223:PAS_chr4_0987
uniprot id: C4R8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

644223:PAS chr2-2 0305
gene id: 644223:PAS_chr2-2_0305
uniprot id: C4R278
names: Similarity
messages: Belongs to the FGGY kinase family.

644223:PAS chr3 0547
gene id: 644223:PAS_chr3_0547
uniprot id: C4R4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0429
gene id: 644223:PAS_chr2-1_0429
uniprot id: C4R0M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

644223:PAS chr2-1 0605
gene id: 644223:PAS_chr2-1_0605
uniprot id: C4R168
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

644223:PAS chr2-2 0494
gene id: 644223:PAS_chr2-2_0494
uniprot id: C4R217
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

644223:PAS chr1-4 0563
gene id: 644223:PAS_chr1-4_0563
uniprot id: C4QYU5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

644223:PAS chr1-4 0614
gene id: 644223:PAS_chr1-4_0614
uniprot id: C4QYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

644223:PAS chr3 1115
gene id: 644223:PAS_chr3_1115
uniprot id: C4R6J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

644223:PAS chr3 0779
gene id: 644223:PAS_chr3_0779
uniprot id: C4R5J6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr4 0180
gene id: 644223:PAS_chr4_0180
uniprot id: C4R731
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

644223:PAS chr3 0761
gene id: 644223:PAS_chr3_0761
uniprot id: C4R5H5
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

644223:PAS c131 0005
gene id: 644223:PAS_c131_0005
uniprot id: C4R383
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

644223:PAS FragB 0026
gene id: 644223:PAS_FragB_0026
uniprot id: C4QZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

644223:PAS chr2-2 0343
gene id: 644223:PAS_chr2-2_0343
uniprot id: C4R239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS chr4 0498
gene id: 644223:PAS_chr4_0498
uniprot id: C4R829
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

644223:PAS chr4 0032
gene id: 644223:PAS_chr4_0032
uniprot id: C4R6N3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

644223:PAS chr4 0737
gene id: 644223:PAS_chr4_0737
uniprot id: C4R8S5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

644223:PAS chr3 0882
gene id: 644223:PAS_chr3_0882
uniprot id: C4R5V3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr2-2 0416
gene id: 644223:PAS_chr2-2_0416
uniprot id: C4R1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

644223:PAS chr4 0158
gene id: 644223:PAS_chr4_0158
uniprot id: C4R708
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

644223:PAS chr2-2 0212
gene id: 644223:PAS_chr2-2_0212
uniprot id: C4R2I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.

644223:PAS chr2-1 0557
gene id: 644223:PAS_chr2-1_0557
uniprot id: C4R117
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

644223:PAS chr3 1254
gene id: 644223:PAS_chr3_1254
uniprot id: C4R6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

644223:PAS chr1-1 0175
gene id: 644223:PAS_chr1-1_0175
uniprot id: C4QWB7
names: Similarity
messages: Belongs to the DapA family.

644223:PAS chr1-3 0004
gene id: 644223:PAS_chr1-3_0004
uniprot id: C4QUZ0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

644223:PAS chr3 1062
gene id: 644223:PAS_chr3_1062
uniprot id: C4R6D8
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

644223:PAS chr4 0874
gene id: 644223:PAS_chr4_0874
uniprot id: C4R969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

644223:PAS chr4 0424
gene id: 644223:PAS_chr4_0424
uniprot id: C4R7V0
names: Similarity
messages: Belongs to the PITHD1 family.

644223:PAS chr4 0405
gene id: 644223:PAS_chr4_0405
uniprot id: C4R7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

644223:PAS chr3 0129
gene id: 644223:PAS_chr3_0129
uniprot id: C4R3M2
names: Similarity
messages: Belongs to the PIAS family.

644223:PAS chr4 0300
gene id: 644223:PAS_chr4_0300
uniprot id: C4R7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-1 0322
gene id: 644223:PAS_chr1-1_0322
uniprot id: C4QWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0868
gene id: 644223:PAS_chr2-1_0868
uniprot id: C4R176
names: Similarity
messages: Belongs to the MYBBP1A family.

644223:PAS chr4 0188
gene id: 644223:PAS_chr4_0188
uniprot id: C4R738
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0138
gene id: 644223:PAS_chr1-4_0138
uniprot id: C4QXJ3
names: Similarity
messages: Belongs to the Tango6 family.

644223:PAS chr3 1043
gene id: 644223:PAS_chr3_1043
uniprot id: C4R6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

644223:PAS chr1-1 0282
gene id: 644223:PAS_chr1-1_0282
uniprot id: C4QWN3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

644223:PAS chr3 0951
gene id: 644223:PAS_chr3_0951
uniprot id: C4R626
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

644223:PAS chr1-4 0320
gene id: 644223:PAS_chr1-4_0320
uniprot id: C4QY38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

644223:PAS chr4 0492
gene id: 644223:PAS_chr4_0492
uniprot id: C4R822
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Nucleus

644223:PAS chr1-1 0375
gene id: 644223:PAS_chr1-1_0375
uniprot id: C4QWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

644223:PAS chr2-1 0604
gene id: 644223:PAS_chr2-1_0604
uniprot id: C4R167
names: Similarity
messages: Belongs to the cullin family.

644223:PAS chr3 0942
gene id: 644223:PAS_chr3_0942
uniprot id: C4R616
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

644223:PAS chr2-1 0814
gene id: 644223:PAS_chr2-1_0814
uniprot id: C4QZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

644223:PAS chr2-1 0392
gene id: 644223:PAS_chr2-1_0392
uniprot id: C4R0I9
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

644223:PAS chr4 0244
gene id: 644223:PAS_chr4_0244
uniprot id: C4R798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

644223:PAS chr1-1 0181
gene id: 644223:PAS_chr1-1_0181
uniprot id: C4QWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

644223:PAS chr4 0233
gene id: 644223:PAS_chr4_0233
uniprot id: C4R789
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

644223:PAS chr3 0681
gene id: 644223:PAS_chr3_0681
uniprot id: C4R594
names: Similarity
messages: Belongs to the oligoribonuclease family.

644223:PAS chr1-4 0251
gene id: 644223:PAS_chr1-4_0251
uniprot id: C4QXW2
names: Similarity
messages: Belongs to the peptidase S8 family.

644223:PAS chr1-3 0243
gene id: 644223:PAS_chr1-3_0243
uniprot id: C4QVN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

644223:PAS chr3 0308
gene id: 644223:PAS_chr3_0308
uniprot id: C4R462
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS c121 0010
gene id: 644223:PAS_c121_0010
uniprot id: C4QZ49
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

644223:PAS chr1-1 0132
gene id: 644223:PAS_chr1-1_0132
uniprot id: C4QW73
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

644223:PAS chr3 0958
gene id: 644223:PAS_chr3_0958
uniprot id: C4R633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

644223:PAS chr3 0422
gene id: 644223:PAS_chr3_0422
uniprot id: C4R4I5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

644223:PAS chr1-4 0231
gene id: 644223:PAS_chr1-4_0231
uniprot id: C4QXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0362
gene id: 644223:PAS_chr2-1_0362
uniprot id: C4R0F8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

644223:PAS chr3 0401
gene id: 644223:PAS_chr3_0401
uniprot id: C4R4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.

644223:PAS chr2-1 0205
gene id: 644223:PAS_chr2-1_0205
uniprot id: C4QZY9
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 1258
gene id: 644223:PAS_chr3_1258
uniprot id: C4R364
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

644223:PAS chr3 0604
gene id: 644223:PAS_chr3_0604
uniprot id: C4R515
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

644223:PAS chr2-2 0054
gene id: 644223:PAS_chr2-2_0054
uniprot id: C4R305
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

644223:PAS chr2-1 0057
gene id: 644223:PAS_chr2-1_0057
uniprot id: C4QZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

644223:PAS chr4 0802
gene id: 644223:PAS_chr4_0802
uniprot id: C4R8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

644223:PAS chr4 0124
gene id: 644223:PAS_chr4_0124
uniprot id: C4R6X6
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

644223:PAS chr2-1 0659
gene id: 644223:PAS_chr2-1_0659
uniprot id: C4R1D0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0015
gene id: 644223:PAS_chr1-4_0015
uniprot id: C4QX76
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

644223:PAS chr1-3 0188
gene id: 644223:PAS_chr1-3_0188
uniprot id: C4QVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

644223:PAS FragB 0014
gene id: 644223:PAS_FragB_0014
uniprot id: C4QZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-1 0138
gene id: 644223:PAS_chr2-1_0138
uniprot id: C4QZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

644223:PAS chr3 0122
gene id: 644223:PAS_chr3_0122
uniprot id: C4R3L6
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

644223:PAS chr3 0417
gene id: 644223:PAS_chr3_0417
uniprot id: C4R4I0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

644223:PAS chr2-2 0097
gene id: 644223:PAS_chr2-2_0097
uniprot id: C4R2V6
names: Similarity
messages: Belongs to the peptidase C48 family.

644223:PAS FragD 0013
gene id: 644223:PAS_FragD_0013
uniprot id: C4R9C0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

644223:PAS chr4 0756
gene id: 644223:PAS_chr4_0756
uniprot id: C4R8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

644223:PAS chr3 0947
gene id: 644223:PAS_chr3_0947
uniprot id: C4R622
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

644223:PAS chr2-2 0219
gene id: 644223:PAS_chr2-2_0219
uniprot id: C4R2H4
names: Similarity
messages: Belongs to the guanylate kinase family.

644223:PAS chr3 0946
gene id: 644223:PAS_chr3_0946
uniprot id: C4R621
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

644223:PAS chr3 0370
gene id: 644223:PAS_chr3_0370
uniprot id: C4R4C8
names: Similarity
messages: Belongs to the MNN1/MNT family.

644223:PAS chr1-1 0350
gene id: 644223:PAS_chr1-1_0350
uniprot id: C4QWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

644223:PAS chr1-3 0227
gene id: 644223:PAS_chr1-3_0227
uniprot id: C4QVL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

644223:PAS chr1-4 0377
gene id: 644223:PAS_chr1-4_0377
uniprot id: C4QY99
names: Similarity
messages: Belongs to the CWC21 family.

644223:PAS chr1-4 0234
gene id: 644223:PAS_chr1-4_0234
uniprot id: C4QXU6
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

644223:PAS chr1-1 0273
gene id: 644223:PAS_chr1-1_0273
uniprot id: C4QWM0
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

644223:PAS chr2-1 0105
gene id: 644223:PAS_chr2-1_0105
uniprot id: C4QZN4
names: Similarity
messages: Belongs to the peptidase M24 family.

644223:PAS chr1-3 0135
gene id: 644223:PAS_chr1-3_0135
uniprot id: C4QVC2
names: Similarity
messages: Belongs to the SAPS family.

644223:PAS chr4 0442
gene id: 644223:PAS_chr4_0442
uniprot id: C4R7X0
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

644223:PAS chr3 0442
gene id: 644223:PAS_chr3_0442
uniprot id: C4R4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

644223:PAS chr3 0402
gene id: 644223:PAS_chr3_0402
uniprot id: C4R4G5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS chr3 1022
gene id: 644223:PAS_chr3_1022
uniprot id: C4R698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

644223:PAS chr2-2 0290
gene id: 644223:PAS_chr2-2_0290
uniprot id: C4R295
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0114
gene id: 644223:PAS_chr2-1_0114
uniprot id: C4QZP4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-1 0072
gene id: 644223:PAS_chr1-1_0072
uniprot id: C4QW09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

644223:PAS chr1-1 0264
gene id: 644223:PAS_chr1-1_0264
uniprot id: C4QWL2
names: Similarity
messages: Belongs to the IFRD family.

644223:PAS chr1-4 0546
gene id: 644223:PAS_chr1-4_0546
uniprot id: C4QYS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

644223:PAS chr1-4 0679
gene id: 644223:PAS_chr1-4_0679
uniprot id: C4QYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

644223:PAS chr2-2 0354
gene id: 644223:PAS_chr2-2_0354
uniprot id: C4R227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

644223:PAS chr2-1 0326
gene id: 644223:PAS_chr2-1_0326
uniprot id: C4R0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

644223:PAS chr1-4 0276
gene id: 644223:PAS_chr1-4_0276
uniprot id: C4QXY8
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr3 0704
gene id: 644223:PAS_chr3_0704
uniprot id: C4R5B9
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

644223:PAS chr2-1 0636
gene id: 644223:PAS_chr2-1_0636
uniprot id: C4R1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0392
gene id: 644223:PAS_chr1-4_0392
uniprot id: C4QYB3
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

644223:PAS chr4 0884
gene id: 644223:PAS_chr4_0884
uniprot id: C4R979
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

644223:PAS chr3 1070
gene id: 644223:PAS_chr3_1070
uniprot id: C4R6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

644223:PAS chr3 0753
gene id: 644223:PAS_chr3_0753
uniprot id: C4R5G7
names: Similarity
messages: Belongs to the RNase PH family.

644223:PAS chr1-3 0242
gene id: 644223:PAS_chr1-3_0242
uniprot id: C4QVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: Nucleus
messages: kinetochore

644223:PAS chr1-4 0109
gene id: 644223:PAS_chr1-4_0109
uniprot id: C4QXG5
names: Similarity
messages: Belongs to the NifU family.

644223:PAS chr2-2 0179
gene id: 644223:PAS_chr2-2_0179
uniprot id: C4R2L7
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS c131 0011
gene id: 644223:PAS_c131_0011
uniprot id: C4R389
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

644223:PAS chr2-1 0799
gene id: 644223:PAS_chr2-1_0799
uniprot id: C4R1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

644223:PAS chr3 1228
gene id: 644223:PAS_chr3_1228
uniprot id: C4R5S3
names: Similarity
messages: Belongs to the MOG1 family.

644223:PAS chr2-2 0127
gene id: 644223:PAS_chr2-2_0127
uniprot id: C4R2S5
names: Function
names: Similarity
messages: Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

644223:PAS chr1-4 0696
gene id: 644223:PAS_chr1-4_0696
uniprot id: C4QZ06
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT family.
messages: Beta-mannosyltransferase involved in cell wall biosynthesis.
messages: Decreases alpha-mannosidase resistant glycans.
messages: Membrane

644223:PAS chr2-2 0203
gene id: 644223:PAS_chr2-2_0203
uniprot id: C4R2J1
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr1-4 0264
gene id: 644223:PAS_chr1-4_0264
uniprot id: C4QXX5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

644223:PAS chr2-1 0146
gene id: 644223:PAS_chr2-1_0146
uniprot id: C4QZS9
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

644223:PAS chr2-2 0276
gene id: 644223:PAS_chr2-2_0276
uniprot id: C4R2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

644223:PAS chr2-1 0423
gene id: 644223:PAS_chr2-1_0423
uniprot id: C4R0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

644223:PAS chr3 0770
gene id: 644223:PAS_chr3_0770
uniprot id: C4R5I6
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

644223:PAS chr4 0579
gene id: 644223:PAS_chr4_0579
uniprot id: C4R8B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

644223:PAS chr3 0751
gene id: 644223:PAS_chr3_0751
uniprot id: C4R5G4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

644223:PAS chr1-1 0372
gene id: 644223:PAS_chr1-1_0372
uniprot id: C4QWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

644223:PAS chr4 0326
gene id: 644223:PAS_chr4_0326
uniprot id: C4R7J4
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

644223:PAS chr4 0496
gene id: 644223:PAS_chr4_0496
uniprot id: C4R826
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr2-1 0272
gene id: 644223:PAS_chr2-1_0272
uniprot id: C4R062
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

644223:PAS chr3 0526
gene id: 644223:PAS_chr3_0526
uniprot id: C4R4T9
names: Similarity
messages: Belongs to the RTT106 family.

644223:PAS chr4 0216
gene id: 644223:PAS_chr4_0216
uniprot id: C4R767
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0625
gene id: 644223:PAS_chr1-4_0625
uniprot id: C4QZ11
names: Similarity
messages: Belongs to the PHAF1 family.

644223:PAS chr1-1 0062
gene id: 644223:PAS_chr1-1_0062
uniprot id: C4QVZ7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

644223:PAS FragB 0077
gene id: 644223:PAS_FragB_0077
uniprot id: C4QZC2
names: Function
names: Subunit
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

644223:PAS chr2-2 0064
gene id: 644223:PAS_chr2-2_0064
uniprot id: C4R2Z5
names: Similarity
messages: Belongs to the SUN family.

644223:PAS chr4 0888
gene id: 644223:PAS_chr4_0888
uniprot id: C4R983
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0228
gene id: 644223:PAS_chr1-1_0228
uniprot id: C4QWH4
names: Similarity
messages: Belongs to the RENT3 family.

644223:PAS chr3 0706
gene id: 644223:PAS_chr3_0706
uniprot id: C4R5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0148
gene id: 644223:PAS_chr4_0148
uniprot id: C4R6Z8
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

644223:PAS chr2-1 0287
gene id: 644223:PAS_chr2-1_0287
uniprot id: C4R076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

644223:PAS chr2-1 0202
gene id: 644223:PAS_chr2-1_0202
uniprot id: C4QZY6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.

644223:PAS chr3 0875
gene id: 644223:PAS_chr3_0875
uniprot id: C4R5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

644223:PAS chr1-4 0613
gene id: 644223:PAS_chr1-4_0613
uniprot id: C4QYZ8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0706
gene id: 644223:PAS_chr4_0706
uniprot id: C4R8P3
names: Similarity
messages: Belongs to the AAR2 family.

644223:PAS chr2-1 0776
gene id: 644223:PAS_chr2-1_0776
uniprot id: C4R1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

644223:PAS chr3 0965
gene id: 644223:PAS_chr3_0965
uniprot id: C4R641
names: Similarity
messages: Belongs to the group II decarboxylase family.

644223:PAS chr1-1 0092
gene id: 644223:PAS_chr1-1_0092
uniprot id: C4QW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

644223:PAS chr2-1 0022
gene id: 644223:PAS_chr2-1_0022
uniprot id: C4QZE7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

644223:PAS chr4 0318
gene id: 644223:PAS_chr4_0318
uniprot id: C4R7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS chr3 0709
gene id: 644223:PAS_chr3_0709
uniprot id: C4R5C4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr4 0066
gene id: 644223:PAS_chr4_0066
uniprot id: C4R6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr3 0240
gene id: 644223:PAS_chr3_0240
uniprot id: C4R3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

644223:PAS chr1-4 0314
gene id: 644223:PAS_chr1-4_0314
uniprot id: C4QY32
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

644223:PAS chr4 0921
gene id: 644223:PAS_chr4_0921
uniprot id: C4R713
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

644223:PAS chr1-4 0319
gene id: 644223:PAS_chr1-4_0319
uniprot id: C4QY37
names: Similarity
messages: Belongs to the RRP12 family.

644223:PAS chr4 0391
gene id: 644223:PAS_chr4_0391
uniprot id: C4R7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

644223:PAS chr4 0128
gene id: 644223:PAS_chr4_0128
uniprot id: C4R6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

644223:PAS chr2-2 0264
gene id: 644223:PAS_chr2-2_0264
uniprot id: C4R2C5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

644223:PAS FragB 0065
gene id: 644223:PAS_FragB_0065
uniprot id: C4QZC3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0547
gene id: 644223:PAS_chr4_0547
uniprot id: C4R882
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS chr1-4 0232
gene id: 644223:PAS_chr1-4_0232
uniprot id: C4QXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

644223:PAS chr1-3 0195
gene id: 644223:PAS_chr1-3_0195
uniprot id: C4QVI6
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

644223:PAS chr2-1 0498
gene id: 644223:PAS_chr2-1_0498
uniprot id: C4R0V4
names: Similarity
messages: Belongs to the polyprenol kinase family.

644223:PAS chr3 0702
gene id: 644223:PAS_chr3_0702
uniprot id: C4R5B5
names: Similarity
messages: Belongs to the BolA/IbaG family.

644223:PAS chr3 0469
gene id: 644223:PAS_chr3_0469
uniprot id: C4R4N2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

644223:PAS chr2-2 0081
gene id: 644223:PAS_chr2-2_0081
uniprot id: C4R2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0572
gene id: 644223:PAS_chr3_0572
uniprot id: C4R4Y4
names: Similarity
messages: Belongs to the CDC123 family.

644223:PAS chr4 0913
gene id: 644223:PAS_chr4_0913
uniprot id: C4R6N8
names: Similarity
messages: Belongs to the peptidase M18 family.

644223:PAS chr3 0693
gene id: 644223:PAS_chr3_0693
uniprot id: C4R5A6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

644223:PAS chr2-2 0224
gene id: 644223:PAS_chr2-2_0224
uniprot id: C4R2G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

644223:PAS chr4 0221
gene id: 644223:PAS_chr4_0221
uniprot id: C4R774
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

644223:PAS chr1-3 0211
gene id: 644223:PAS_chr1-3_0211
uniprot id: C4QVK2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

644223:PAS chr4 0866
gene id: 644223:PAS_chr4_0866
uniprot id: C4R961
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

644223:PAS chr1-4 0112
gene id: 644223:PAS_chr1-4_0112
uniprot id: C4QXG8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

644223:PAS chr2-2 0158
gene id: 644223:PAS_chr2-2_0158
uniprot id: C4R2P5
names: Function
names: Similarity
messages: Belongs to the LCL2 family.
messages: Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.

644223:PAS chr3 0804
gene id: 644223:PAS_chr3_0804
uniprot id: C4R5M1
names: Similarity
messages: Belongs to the RMD1/sif2 family.

644223:PAS chr2-2 0417
gene id: 644223:PAS_chr2-2_0417
uniprot id: C4R1W7
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

644223:PAS chr1-4 0152
gene id: 644223:PAS_chr1-4_0152
uniprot id: C4QXK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.
messages: Belongs to the CNOT2/3/5 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-2 0053
gene id: 644223:PAS_chr2-2_0053
uniprot id: C4R306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

644223:PAS chr2-2 0044
gene id: 644223:PAS_chr2-2_0044
uniprot id: C4R316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

644223:PAS chr4 0796
gene id: 644223:PAS_chr4_0796
uniprot id: C4R8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

644223:PAS chr3 1098
gene id: 644223:PAS_chr3_1098
uniprot id: C4R6H7
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

644223:PAS chr3 0763
gene id: 644223:PAS_chr3_0763
uniprot id: C4R5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr4 0592
gene id: 644223:PAS_chr4_0592
uniprot id: C4R8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0022
gene id: 644223:PAS_chr3_0022
uniprot id: C4R3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644223:PAS chr1-4 0423
gene id: 644223:PAS_chr1-4_0423
uniprot id: C4QYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0787
gene id: 644223:PAS_chr4_0787
uniprot id: C4R8X8
names: Similarity
messages: Belongs to the phospholipid scramblase family.

644223:PAS chr1-4 0615
gene id: 644223:PAS_chr1-4_0615
uniprot id: C4QZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-1 0491
gene id: 644223:PAS_chr1-1_0491
uniprot id: C4QWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0179
gene id: 644223:PAS_chr2-1_0179
uniprot id: C4QZW4
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

644223:PAS chr1-4 0149
gene id: 644223:PAS_chr1-4_0149
uniprot id: C4QXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-1 0661
gene id: 644223:PAS_chr2-1_0661
uniprot id: C4R1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

644223:PAS chr1-1 0299
gene id: 644223:PAS_chr1-1_0299
uniprot id: C4QWQ3
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

644223:PAS chr1-4 0202
gene id: 644223:PAS_chr1-4_0202
uniprot id: C4QXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0831
gene id: 644223:PAS_chr4_0831
uniprot id: C4R925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

644223:PAS chr1-1 0447
gene id: 644223:PAS_chr1-1_0447
uniprot id: C4QX51
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

644223:PAS chr3 0932
gene id: 644223:PAS_chr3_0932
uniprot id: C4R606
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644223:PAS chr1-1 0180
gene id: 644223:PAS_chr1-1_0180
uniprot id: Q9P4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex and SAR1.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).

644223:PAS chr1-3 0182
gene id: 644223:PAS_chr1-3_0182
uniprot id: C4QVH2
names: Similarity
messages: Belongs to the CEF1 family.

644223:PAS chr2-1 0652
gene id: 644223:PAS_chr2-1_0652
uniprot id: C4R1C3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr3 0957
gene id: 644223:PAS_chr3_0957
uniprot id: C4R632
names: Similarity
messages: Belongs to the cytochrome P450 family.

644223:PAS chr4 0808
gene id: 644223:PAS_chr4_0808
uniprot id: C4R903
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

644223:PAS chr2-1 0050
gene id: 644223:PAS_chr2-1_0050
uniprot id: C4QZH7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0139
gene id: 644223:PAS_chr4_0139
uniprot id: C4R6Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

644223:PAS chr3 1189
gene id: 644223:PAS_chr3_1189
uniprot id: C4R4I8
names: Subcellular Location Annotation
messages: Golgi apparatus

644223:PAS chr3 0219
gene id: 644223:PAS_chr3_0219
uniprot id: C4R3W4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

644223:PAS chr2-2 0169
gene id: 644223:PAS_chr2-2_0169
uniprot id: C4R2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0090
gene id: 644223:PAS_chr4_0090
uniprot id: C4R6U2
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

644223:PAS chr1-4 0484
gene id: 644223:PAS_chr1-4_0484
uniprot id: C4QYL3
names: Subcellular Location Annotation
names: Subunit
messages: Component of the mitochondrial large ribosomal subunit.
messages: Mitochondrion

644223:PAS chr1-4 0352
gene id: 644223:PAS_chr1-4_0352
uniprot id: C4QY71
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

644223:PAS chr4 0414
gene id: 644223:PAS_chr4_0414
uniprot id: C4R7T8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

644223:PAS chr1-1 0421
gene id: 644223:PAS_chr1-1_0421
uniprot id: C4QX26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

644223:PAS chr3 0966
gene id: 644223:PAS_chr3_0966
uniprot id: C4R642
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0685
gene id: 644223:PAS_chr1-4_0685
uniprot id: C4QYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

644223:PAS chr3 1190
gene id: 644223:PAS_chr3_1190
uniprot id: C4R4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

644223:PAS chr1-4 0564
gene id: 644223:PAS_chr1-4_0564
uniprot id: C4QYU6
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

644223:PAS chr1-4 0195
gene id: 644223:PAS_chr1-4_0195
uniprot id: C4QXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

644223:PAS chr1-4 0630
gene id: 644223:PAS_chr1-4_0630
uniprot id: C4QZ16
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

644223:PAS chr2-1 0807
gene id: 644223:PAS_chr2-1_0807
uniprot id: C4QZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

644223:PAS chr2-2 0318
gene id: 644223:PAS_chr2-2_0318
uniprot id: C4R264
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

644223:PAS chr2-1 0816
gene id: 644223:PAS_chr2-1_0816
uniprot id: C4QZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

644223:PAS chr1-4 0644
gene id: 644223:PAS_chr1-4_0644
uniprot id: C4QZ31
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

644223:PAS chr3 0388
gene id: 644223:PAS_chr3_0388
uniprot id: C4R4E8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

644223:PAS chr2-1 0728
gene id: 644223:PAS_chr2-1_0728
uniprot id: C4R1K3
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

644223:PAS chr2-2 0242
gene id: 644223:PAS_chr2-2_0242
uniprot id: C4R2F0
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

644223:PAS chr4 0551
gene id: 644223:PAS_chr4_0551
uniprot id: C4R886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

644223:PAS chr3 0475
gene id: 644223:PAS_chr3_0475
uniprot id: C4R4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-4 0233
gene id: 644223:PAS_chr1-4_0233
uniprot id: C4QXU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

644223:PAS chr4 0401
gene id: 644223:PAS_chr4_0401
uniprot id: C4R7S5
names: Similarity
messages: Belongs to the R-transferase family.

644223:PAS chr3 0788
gene id: 644223:PAS_chr3_0788
uniprot id: C4R5K6
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

644223:PAS chr3 0114
gene id: 644223:PAS_chr3_0114
uniprot id: C4R3K8
names: Similarity
messages: Belongs to the CIA30 family.

644223:PAS chr2-2 0213
gene id: 644223:PAS_chr2-2_0213
uniprot id: C4R2I0
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

644223:PAS chr1-4 0262
gene id: 644223:PAS_chr1-4_0262
uniprot id: C4QXX2
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-1 0215
gene id: 644223:PAS_chr1-1_0215
uniprot id: C4QWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

644223:PAS chr4 0035
gene id: 644223:PAS_chr4_0035
uniprot id: C4R6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

644223:PAS chr2-2 0228
gene id: 644223:PAS_chr2-2_0228
uniprot id: C4R2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

644223:PAS chr3 1105
gene id: 644223:PAS_chr3_1105
uniprot id: C4R6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

644223:PAS chr3 0764
gene id: 644223:PAS_chr3_0764
uniprot id: C4R5H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

644223:PAS chr2-1 0268
gene id: 644223:PAS_chr2-1_0268
uniprot id: C4R056
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

644223:PAS chr2-1 0443
gene id: 644223:PAS_chr2-1_0443
uniprot id: C4R0P6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

644223:PAS chr1-4 0271
gene id: 644223:PAS_chr1-4_0271
uniprot id: C4QXY2
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr1-4 0101
gene id: 644223:PAS_chr1-4_0101
uniprot id: C4QXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

644223:PAS chr2-2 0021
gene id: 644223:PAS_chr2-2_0021
uniprot id: C4R342
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0551
gene id: 644223:PAS_chr1-4_0551
uniprot id: C4QYT3
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

644223:PAS chr1-4 0293
gene id: 644223:PAS_chr1-4_0293
uniprot id: C4QY08
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

644223:PAS chr3 0277
gene id: 644223:PAS_chr3_0277
uniprot id: C4R430
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

644223:PAS chr4 0039
gene id: 644223:PAS_chr4_0039
uniprot id: C4R6P0
names: Similarity
messages: Belongs to the lysophospholipase family.

644223:PAS chr4 0600
gene id: 644223:PAS_chr4_0600
uniprot id: C4R8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr3 1011
gene id: 644223:PAS_chr3_1011
uniprot id: C4R686
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

644223:PAS chr2-1 0667
gene id: 644223:PAS_chr2-1_0667
uniprot id: C4R1D9
names: Similarity
messages: Belongs to the peptidase M24B family.

644223:PAS chr4 0289
gene id: 644223:PAS_chr4_0289
uniprot id: C4R7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection
messages: Cytoplasm

644223:PAS chr2-1 0415
gene id: 644223:PAS_chr2-1_0415
uniprot id: C4R0L2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

644223:PAS chr4 0279
gene id: 644223:PAS_chr4_0279
uniprot id: C4R7D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

644223:PAS chr1-1 0147
gene id: 644223:PAS_chr1-1_0147
uniprot id: C4QW88
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

644223:PAS chr1-4 0394
gene id: 644223:PAS_chr1-4_0394
uniprot id: C4QYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

644223:PAS chr4 0852
gene id: 644223:PAS_chr4_0852
uniprot id: C4R945
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

644223:PAS chr1-4 0536
gene id: 644223:PAS_chr1-4_0536
uniprot id: C4QYR6
names: Similarity
messages: Belongs to the BolA/IbaG family.

644223:PAS chr3 0279
gene id: 644223:PAS_chr3_0279
uniprot id: C4R432
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

644223:PAS chr4 0296
gene id: 644223:PAS_chr4_0296
uniprot id: C4R7F8
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

644223:PAS chr4 0728
gene id: 644223:PAS_chr4_0728
uniprot id: C4R8R5
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr3 0694
gene id: 644223:PAS_chr3_0694
uniprot id: C4R5A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAN1 family.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.
messages: Component of the PAN1 actin cytoskeleton-regulatory complex.

644223:PAS chr3 0633
gene id: 644223:PAS_chr3_0633
uniprot id: C4R546
names: Similarity
messages: Belongs to the peptidase S10 family.

644223:PAS chr3 0870
gene id: 644223:PAS_chr3_0870
uniprot id: C4R5U0
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

644223:PAS chr4 0626
gene id: 644223:PAS_chr4_0626
uniprot id: C4R8G1
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0587
gene id: 644223:PAS_chr4_0587
uniprot id: C4R8C2
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

644223:PAS chr1-4 0334
gene id: 644223:PAS_chr1-4_0334
uniprot id: C4QY54
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

644223:PAS chr1-1 0061
gene id: 644223:PAS_chr1-1_0061
uniprot id: C4QVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

644223:PAS chr2-2 0148
gene id: 644223:PAS_chr2-2_0148
uniprot id: C4R2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

644223:PAS chr2-1 0216
gene id: 644223:PAS_chr2-1_0216
uniprot id: C4R002
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

644223:PAS chr4 0504
gene id: 644223:PAS_chr4_0504
uniprot id: C4R835
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1039
gene id: 644223:PAS_chr3_1039
uniprot id: C4R6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

644223:PAS chr3 0316
gene id: 644223:PAS_chr3_0316
uniprot id: C4R469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

644223:PAS chr1-1 0410
gene id: 644223:PAS_chr1-1_0410
uniprot id: C4QX14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

644223:PAS chr3 0124
gene id: 644223:PAS_chr3_0124
uniprot id: C4R3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

644223:PAS chr3 0834
gene id: 644223:PAS_chr3_0834
uniprot id: C4R5Q0
names: Similarity
messages: Belongs to the transketolase family.

644223:PAS chr2-2 0157
gene id: 644223:PAS_chr2-2_0157
uniprot id: C4R2P6
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

644223:PAS chr3 0384
gene id: 644223:PAS_chr3_0384
uniprot id: C4R4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

644223:PAS chr1-4 0539
gene id: 644223:PAS_chr1-4_0539
uniprot id: C4QYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

644223:PAS chr1-3 0133
gene id: 644223:PAS_chr1-3_0133
uniprot id: C4QVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Membrane

644223:PAS chr2-1 0081
gene id: 644223:PAS_chr2-1_0081
uniprot id: C4QZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

644223:PAS chr2-1 0292
gene id: 644223:PAS_chr2-1_0292
uniprot id: C4R081
names: Subunit
messages: Homodimer.

644223:PAS chr1-4 0113
gene id: 644223:PAS_chr1-4_0113
uniprot id: C4QXG9
names: Similarity
messages: Belongs to the SGT family.

644223:PAS chr3 0413
gene id: 644223:PAS_chr3_0413
uniprot id: C4R4H6
names: Similarity
messages: Belongs to the TSR2 family.

644223:PAS chr3 0760
gene id: 644223:PAS_chr3_0760
uniprot id: C4R5H4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0609
gene id: 644223:PAS_chr4_0609
uniprot id: C4R8E4
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

644223:PAS chr2-1 0612
gene id: 644223:PAS_chr2-1_0612
uniprot id: C4R177
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

644223:PAS chr2-1 0649
gene id: 644223:PAS_chr2-1_0649
uniprot id: C4R1B9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0610
gene id: 644223:PAS_chr2-1_0610
uniprot id: C4R173
names: Function
names: Similarity
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

644223:PAS chr4 0652
gene id: 644223:PAS_chr4_0652
uniprot id: C4R8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0585
gene id: 644223:PAS_chr3_0585
uniprot id: C4R4Z6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

644223:PAS chr1-1 0054
gene id: 644223:PAS_chr1-1_0054
uniprot id: C4QVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

644223:PAS chr2-1 0753
gene id: 644223:PAS_chr2-1_0753
uniprot id: C4R1N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

644223:PAS chr1-1 0182
gene id: 644223:PAS_chr1-1_0182
uniprot id: C4QWC4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

644223:PAS chr1-3 0158
gene id: 644223:PAS_chr1-3_0158
uniprot id: C4QVE6
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

644223:PAS chr1-4 0523
gene id: 644223:PAS_chr1-4_0523
uniprot id: C4QYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

644223:PAS chr1-3 0160
gene id: 644223:PAS_chr1-3_0160
uniprot id: C4QVE8
names: Similarity
messages: Belongs to the SELO family.

644223:PAS chr2-2 0128
gene id: 644223:PAS_chr2-2_0128
uniprot id: C4R2S4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0576
gene id: 644223:PAS_chr4_0576
uniprot id: C4R8B0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644223:PAS chr3 0372
gene id: 644223:PAS_chr3_0372
uniprot id: C4R4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

644223:PAS chr2-2 0045
gene id: 644223:PAS_chr2-2_0045
uniprot id: C4R315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

644223:PAS chr1-1 0168
gene id: 644223:PAS_chr1-1_0168
uniprot id: C4QWB0
names: Similarity
messages: Belongs to the patched family.

644223:PAS chr4 0299
gene id: 644223:PAS_chr4_0299
uniprot id: C4R7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

644223:PAS chr3 0898
gene id: 644223:PAS_chr3_0898
uniprot id: C4R5W9
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

644223:PAS chr1-4 0220
gene id: 644223:PAS_chr1-4_0220
uniprot id: C4QXT2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0135
gene id: 644223:PAS_chr1-4_0135
uniprot id: C4QXJ0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

644223:PAS chr2-2 0303
gene id: 644223:PAS_chr2-2_0303
uniprot id: C4R280
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

644223:PAS chr4 0906
gene id: 644223:PAS_chr4_0906
uniprot id: C4R9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr3 0398
gene id: 644223:PAS_chr3_0398
uniprot id: C4R4G0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

644223:PAS chr1-3 0256
gene id: 644223:PAS_chr1-3_0256
uniprot id: C4QVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

644223:PAS chr2-2 0112
gene id: 644223:PAS_chr2-2_0112
uniprot id: C4R2U0
names: Cofactor
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.

644223:PAS chr3 0068
gene id: 644223:PAS_chr3_0068
uniprot id: C4R3G2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0647
gene id: 644223:PAS_chr4_0647
uniprot id: C4R8I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

644223:PAS chr1-4 0237
gene id: 644223:PAS_chr1-4_0237
uniprot id: C4QXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

644223:PAS chr2-1 0226
gene id: 644223:PAS_chr2-1_0226
uniprot id: C4R012
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

644223:PAS chr2-2 0110
gene id: 644223:PAS_chr2-2_0110
uniprot id: C4R2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG27 family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr3 0431
gene id: 644223:PAS_chr3_0431
uniprot id: C4R4J5
names: Subcellular Location Annotation
messages: Nucleus membrane

644223:PAS chr2-1 0481
gene id: 644223:PAS_chr2-1_0481
uniprot id: C4R0T7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

644223:PAS chr2-1 0082
gene id: 644223:PAS_chr2-1_0082
uniprot id: C4QZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

644223:PAS chr1-3 0215
gene id: 644223:PAS_chr1-3_0215
uniprot id: C4QVK5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0306
gene id: 644223:PAS_chr3_0306
uniprot id: C4R460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

644223:PAS chr2-2 0048
gene id: 644223:PAS_chr2-2_0048
uniprot id: C4R312
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

644223:PAS FragD 0018
gene id: 644223:PAS_FragD_0018
uniprot id: C4R9B5
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0304
gene id: 644223:PAS_chr2-2_0304
uniprot id: C4R279
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0480
gene id: 644223:PAS_chr1-4_0480
uniprot id: C4QYK9
names: Similarity
messages: Belongs to the ZPR1 family.

644223:PAS chr3 0246
gene id: 644223:PAS_chr3_0246
uniprot id: C4R3Z7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

644223:PAS chr2-1 0660
gene id: 644223:PAS_chr2-1_0660
uniprot id: C4R1D1
names: Similarity
messages: Belongs to the PurH family.

644223:PAS chr1-1 0274
gene id: 644223:PAS_chr1-1_0274
uniprot id: C4QWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0033
gene id: 644223:PAS_chr4_0033
uniprot id: C4R6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

644223:PAS chr4 0905
gene id: 644223:PAS_chr4_0905
uniprot id: C4R9A0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

644223:PAS chr4 0258
gene id: 644223:PAS_chr4_0258
uniprot id: C4R7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

644223:PAS chr2-1 0135
gene id: 644223:PAS_chr2-1_0135
uniprot id: C4QZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

644223:PAS chr4 0179
gene id: 644223:PAS_chr4_0179
uniprot id: C4R730
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

644223:PAS chr2-1 0373
gene id: 644223:PAS_chr2-1_0373
uniprot id: C4R0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

644223:PAS chr2-1 0102
gene id: 644223:PAS_chr2-1_0102
uniprot id: C4QZN0
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr2-1 0541
gene id: 644223:PAS_chr2-1_0541
uniprot id: C4R100
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

644223:PAS chr4 0441
gene id: 644223:PAS_chr4_0441
uniprot id: C4R7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

644223:PAS chr3 0566
gene id: 644223:PAS_chr3_0566
uniprot id: C4R4X8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

644223:PAS chr3 0112
gene id: 644223:PAS_chr3_0112
uniprot id: C4R3K6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

644223:PAS chr1-4 0158
gene id: 644223:PAS_chr1-4_0158
uniprot id: C4QXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

644223:PAS chr1-1 0314
gene id: 644223:PAS_chr1-1_0314
uniprot id: C4QWR8
names: Similarity
messages: Belongs to the VPS54 family.

644223:PAS chr3 0721
gene id: 644223:PAS_chr3_0721
uniprot id: C4R5D2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

644223:PAS chr3 0640
gene id: 644223:PAS_chr3_0640
uniprot id: C4R553
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

644223:PAS chr2-1 0722
gene id: 644223:PAS_chr2-1_0722
uniprot id: C4R1J7
names: Similarity
messages: Belongs to the EIS1 family.

644223:PAS chr3 0365
gene id: 644223:PAS_chr3_0365
uniprot id: C4R4C3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS chr1-4 0084
gene id: 644223:PAS_chr1-4_0084
uniprot id: C4QXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

644223:PAS chr3 1204
gene id: 644223:PAS_chr3_1204
uniprot id: C4R540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: nuclear pore complex

644223:PAS chr2-1 0194
gene id: 644223:PAS_chr2-1_0194
uniprot id: C4QZX8
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

644223:PAS chr1-3 0150
gene id: 644223:PAS_chr1-3_0150
uniprot id: C4QVD7
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

644223:PAS chr2-1 0384
gene id: 644223:PAS_chr2-1_0384
uniprot id: C4R0I2
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

644223:PAS chr3 1122
gene id: 644223:PAS_chr3_1122
uniprot id: C4R6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

644223:PAS chr4 0078
gene id: 644223:PAS_chr4_0078
uniprot id: C4R6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

644223:PAS chr1-3 0230
gene id: 644223:PAS_chr1-3_0230
uniprot id: C4QVL8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0861
gene id: 644223:PAS_chr3_0861
uniprot id: C4R5S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

644223:PAS chr2-2 0109
gene id: 644223:PAS_chr2-2_0109
uniprot id: C4R2U4
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

644223:PAS chr1-3 0238
gene id: 644223:PAS_chr1-3_0238
uniprot id: C4QVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

644223:PAS chr2-2 0275
gene id: 644223:PAS_chr2-2_0275
uniprot id: C4R2B4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

644223:PAS chr4 0267
gene id: 644223:PAS_chr4_0267
uniprot id: C4R7C6
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

644223:PAS chr2-1 0394
gene id: 644223:PAS_chr2-1_0394
uniprot id: C4R0J1
names: Similarity
messages: Belongs to the TFIIB family.

644223:PAS chr1-1 0035
gene id: 644223:PAS_chr1-1_0035
uniprot id: C4QVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

644223:PAS chr3 0671
gene id: 644223:PAS_chr3_0671
uniprot id: C4R583
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

644223:PAS chr1-4 0284
gene id: 644223:PAS_chr1-4_0284
uniprot id: C4QXZ7
names: Similarity
messages: Belongs to the NifU family.

644223:PAS chr3 0757
gene id: 644223:PAS_chr3_0757
uniprot id: C4R5H1
names: Similarity
messages: Belongs to the CBF/MAK21 family.

644223:PAS chr1-4 0071
gene id: 644223:PAS_chr1-4_0071
uniprot id: C4QXC7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

644223:PAS chr2-1 0692
gene id: 644223:PAS_chr2-1_0692
uniprot id: C4R1G5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0011
gene id: 644223:PAS_chr1-3_0011
uniprot id: C4QUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0048
gene id: 644223:PAS_chr2-1_0048
uniprot id: C4QZH4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0297
gene id: 644223:PAS_chr1-3_0297
uniprot id: C4QV79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the respiratory chain complex III/complex IV supercomplex.
messages: Belongs to the RCF1 family.
messages: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
messages: Mitochondrion membrane

644223:PAS chr3 0847
gene id: 644223:PAS_chr3_0847
uniprot id: C4R5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

644223:PAS chr3 1012
gene id: 644223:PAS_chr3_1012
uniprot id: C4R687
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

644223:PAS FragB 0050
gene id: 644223:PAS_FragB_0050
uniprot id: C4QZA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

644223:PAS chr1-4 0440
gene id: 644223:PAS_chr1-4_0440
uniprot id: C4QYG8
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr3 0385
gene id: 644223:PAS_chr3_0385
uniprot id: C4R4E4
names: Similarity
messages: Belongs to the RNase PH family.

644223:PAS chr3 1014
gene id: 644223:PAS_chr3_1014
uniprot id: C4R689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr3 0823
gene id: 644223:PAS_chr3_0823
uniprot id: C4R5P0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

644223:PAS chr2-2 0065
gene id: 644223:PAS_chr2-2_0065
uniprot id: C4R2Z3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0106
gene id: 644223:PAS_chr1-1_0106
uniprot id: C4QW45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr1-1 0192
gene id: 644223:PAS_chr1-1_0192
uniprot id: C4QWD5
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

644223:PAS chr1-4 0125
gene id: 644223:PAS_chr1-4_0125
uniprot id: C4QXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

644223:PAS chr1-1 0480
gene id: 644223:PAS_chr1-1_0480
uniprot id: C4QWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

644223:PAS chr1-3 0024
gene id: 644223:PAS_chr1-3_0024
uniprot id: C4QV06
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr3 0094
gene id: 644223:PAS_chr3_0094
uniprot id: C4R3I8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

644223:PAS chr3 1087
gene id: 644223:PAS_chr3_1087
uniprot id: C4R6G8
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr3 0535
gene id: 644223:PAS_chr3_0535
uniprot id: C4R4U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr4 0337
gene id: 644223:PAS_chr4_0337
uniprot id: C4R7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0863
gene id: 644223:PAS_chr2-1_0863
uniprot id: C4R126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

644223:PAS chr3 0047
gene id: 644223:PAS_chr3_0047
uniprot id: C4R3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

644223:PAS chr1-4 0350
gene id: 644223:PAS_chr1-4_0350
uniprot id: C4QY69
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0286
gene id: 644223:PAS_chr1-4_0286
uniprot id: C4QY00
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0223
gene id: 644223:PAS_chr2-1_0223
uniprot id: C4R009
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

644223:PAS chr4 0072
gene id: 644223:PAS_chr4_0072
uniprot id: C4R6S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

644223:PAS chr1-3 0251
gene id: 644223:PAS_chr1-3_0251
uniprot id: C4QVP2
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

644223:PAS chr2-2 0192
gene id: 644223:PAS_chr2-2_0192
uniprot id: C4R2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS chr1-4 0629
gene id: 644223:PAS_chr1-4_0629
uniprot id: C4QZ15
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

644223:PAS chr3 1166
gene id: 644223:PAS_chr3_1166
uniprot id: C4R3X4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0205
gene id: 644223:PAS_chr4_0205
uniprot id: C4R756
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0257
gene id: 644223:PAS_chr3_0257
uniprot id: C4R408
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

644223:PAS chr1-3 0164
gene id: 644223:PAS_chr1-3_0164
uniprot id: C4QVF3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0460
gene id: 644223:PAS_chr3_0460
uniprot id: C4R4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

644223:PAS chr3 0953
gene id: 644223:PAS_chr3_0953
uniprot id: C4R628
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: May be involved in vacuolar sorting and osmoregulation.
messages: Vacuole membrane

644223:PAS chr3 1120
gene id: 644223:PAS_chr3_1120
uniprot id: C4R6K1
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

644223:PAS chr2-2 0358
gene id: 644223:PAS_chr2-2_0358
uniprot id: C4R223
names: Similarity
messages: Belongs to the MIP18 family.

644223:PAS chr2-2 0144
gene id: 644223:PAS_chr2-2_0144
uniprot id: C4R2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

644223:PAS chr3 1088
gene id: 644223:PAS_chr3_1088
uniprot id: C4R6H0
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

644223:PAS chr2-1 0447
gene id: 644223:PAS_chr2-1_0447
uniprot id: C4R0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

644223:PAS chr4 0048
gene id: 644223:PAS_chr4_0048
uniprot id: C4R6Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

644223:PAS chr1-4 0522
gene id: 644223:PAS_chr1-4_0522
uniprot id: C4QYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

644223:PAS chr1-4 0653
gene id: 644223:PAS_chr1-4_0653
uniprot id: C4QX71
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

644223:PAS chr1-1 0124
gene id: 644223:PAS_chr1-1_0124
uniprot id: C4QW63
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

644223:PAS chr4 0098
gene id: 644223:PAS_chr4_0098
uniprot id: C4R6U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

644223:PAS chr4 0929
gene id: 644223:PAS_chr4_0929
uniprot id: C4R779
names: Similarity
messages: Belongs to the HTATSF1 family.

644223:PAS chr4 0083
gene id: 644223:PAS_chr4_0083
uniprot id: C4R6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

644223:PAS chr4 0791
gene id: 644223:PAS_chr4_0791
uniprot id: C4R8Y5
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

644223:PAS chr3 0591
gene id: 644223:PAS_chr3_0591
uniprot id: C4R503
names: Similarity
messages: Belongs to the asparaginase 1 family.

644223:PAS chr2-1 0546
gene id: 644223:PAS_chr2-1_0546
uniprot id: C4R105
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

644223:PAS chr1-4 0697
gene id: 644223:PAS_chr1-4_0697
uniprot id: C4QXY7
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

644223:PAS chr1-4 0414
gene id: 644223:PAS_chr1-4_0414
uniprot id: C4QYE0
names: Similarity
messages: Belongs to the PRP18 family.

644223:PAS chr3 1259
gene id: 644223:PAS_chr3_1259
uniprot id: C4R371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

644223:PAS chr2-1 0530
gene id: 644223:PAS_chr2-1_0530
uniprot id: C4R0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr1-1 0377
gene id: 644223:PAS_chr1-1_0377
uniprot id: C4QWY2
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

644223:PAS chr2-1 0580
gene id: 644223:PAS_chr2-1_0580
uniprot id: C4R142
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

644223:PAS chr3 0909
gene id: 644223:PAS_chr3_0909
uniprot id: C4R5Y2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0406
gene id: 644223:PAS_chr3_0406
uniprot id: C4R4G9
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

644223:PAS chr3 0086
gene id: 644223:PAS_chr3_0086
uniprot id: C4R3I2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr2-1 0207
gene id: 644223:PAS_chr2-1_0207
uniprot id: C4QZZ1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

644223:PAS chr4 0514
gene id: 644223:PAS_chr4_0514
uniprot id: C4R845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644223:PAS chr4 0399
gene id: 644223:PAS_chr4_0399
uniprot id: C4R7S4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-2 0062
gene id: 644223:PAS_chr2-2_0062
uniprot id: C4R2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

644223:PAS chr2-1 0736
gene id: 644223:PAS_chr2-1_0736
uniprot id: C4R1L2
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

644223:PAS chr3 1117
gene id: 644223:PAS_chr3_1117
uniprot id: C4R6J8
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

644223:PAS chr1-4 0431
gene id: 644223:PAS_chr1-4_0431
uniprot id: C4QYF8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0306
gene id: 644223:PAS_chr1-3_0306
uniprot id: C4QVM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

644223:PAS chr3 0713
gene id: 644223:PAS_chr3_0713
uniprot id: C4R5C7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0204
gene id: 644223:PAS_chr2-2_0204
uniprot id: C4R2J0
names: Similarity
messages: Belongs to the PPC synthetase family.

644223:PAS chr2-1 0797
gene id: 644223:PAS_chr2-1_0797
uniprot id: C4R1T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

644223:PAS chr4 0738
gene id: 644223:PAS_chr4_0738
uniprot id: C4R8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

644223:PAS chr1-1 0283
gene id: 644223:PAS_chr1-1_0283
uniprot id: C4QWN4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

644223:PAS chr1-1 0002
gene id: 644223:PAS_chr1-1_0002
uniprot id: C4QVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

644223:PAS chr2-1 0400
gene id: 644223:PAS_chr2-1_0400
uniprot id: C4R0J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

644223:PAS chr1-1 0376
gene id: 644223:PAS_chr1-1_0376
uniprot id: C4QWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

644223:PAS chr1-3 0016
gene id: 644223:PAS_chr1-3_0016
uniprot id: C4QUZ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr3 0961
gene id: 644223:PAS_chr3_0961
uniprot id: C4R636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

644223:PAS chr1-1 0014
gene id: 644223:PAS_chr1-1_0014
uniprot id: C4QVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

644223:PAS chr1-1 0087
gene id: 644223:PAS_chr1-1_0087
uniprot id: C4QW24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

644223:PAS chr4 0167
gene id: 644223:PAS_chr4_0167
uniprot id: Q9Y751
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Cytoplasm
messages: Preautophagosomal structure membrane
messages: Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy) (PubMed:11856375, PubMed:14585290, PubMed:12839986, PubMed:19605559). Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity).
messages: The first GRAM domain is required for association with the micropexophagic apparatus (PubMed:12839986).

644223:PAS chr1-1 0336
gene id: 644223:PAS_chr1-1_0336
uniprot id: C4QWU0
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0126
gene id: 644223:PAS_chr2-2_0126
uniprot id: C4R2S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0094
gene id: 644223:PAS_chr1-4_0094
uniprot id: C4QXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

644223:PAS chr3 0335
gene id: 644223:PAS_chr3_0335
uniprot id: C4R487
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

644223:PAS chr1-1 0221
gene id: 644223:PAS_chr1-1_0221
uniprot id: C4QWG8
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0501
gene id: 644223:PAS_chr4_0501
uniprot id: C4R832
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0255
gene id: 644223:PAS_chr4_0255
uniprot id: C4R7B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

644223:PAS chr1-1 0267
gene id: 644223:PAS_chr1-1_0267
uniprot id: C4QWL5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr1-3 0100
gene id: 644223:PAS_chr1-3_0100
uniprot id: C4QV87
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

644223:PAS chr4 0508
gene id: 644223:PAS_chr4_0508
uniprot id: C4R839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

644223:PAS chr1-1 0137
gene id: 644223:PAS_chr1-1_0137
uniprot id: C4QW78
names: Similarity
messages: Belongs to the SEN15 family.

644223:PAS FragB 0006
gene id: 644223:PAS_FragB_0006
uniprot id: C4QZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

644223:PAS chr2-1 0349
gene id: 644223:PAS_chr2-1_0349
uniprot id: C4R0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

644223:PAS chr2-1 0800
gene id: 644223:PAS_chr2-1_0800
uniprot id: C4R1T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr3 0543
gene id: 644223:PAS_chr3_0543
uniprot id: C4R4V5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0765
gene id: 644223:PAS_chr3_0765
uniprot id: C4R5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

644223:PAS chr4 0548
gene id: 644223:PAS_chr4_0548
uniprot id: C4R883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr4 0247
gene id: 644223:PAS_chr4_0247
uniprot id: C4R7A3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

644223:PAS chr2-1 0668
gene id: 644223:PAS_chr2-1_0668
uniprot id: C4R1E0
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

644223:PAS chr4 0301
gene id: 644223:PAS_chr4_0301
uniprot id: C4R7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

644223:PAS chr2-1 0275
gene id: 644223:PAS_chr2-1_0275
uniprot id: C4R065
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr2-1 0577
gene id: 644223:PAS_chr2-1_0577
uniprot id: C4R138
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

644223:PAS chr1-3 0022
gene id: 644223:PAS_chr1-3_0022
uniprot id: C4QV04
names: Subcellular Location Annotation
messages: Cytoplasm

644223:PAS chr1-3 0143
gene id: 644223:PAS_chr1-3_0143
uniprot id: C4QVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus
messages: telomere

644223:PAS chr3 1007
gene id: 644223:PAS_chr3_1007
uniprot id: C4R682
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

644223:PAS chr4 0276
gene id: 644223:PAS_chr4_0276
uniprot id: C4R7D5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

644223:PAS chr4 0584
gene id: 644223:PAS_chr4_0584
uniprot id: C4R8B8
names: Similarity
messages: Belongs to the peptidase A1 family.

644223:PAS chr1-4 0698
gene id: 644223:PAS_chr1-4_0698
uniprot id: C4QXZ3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0015
gene id: 644223:PAS_chr1-1_0015
uniprot id: C4QVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

644223:PAS chr3 0100
gene id: 644223:PAS_chr3_0100
uniprot id: C4R3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0302
gene id: 644223:PAS_chr1-4_0302
uniprot id: C4QY19
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr2-1 0594
gene id: 644223:PAS_chr2-1_0594
uniprot id: C4R157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

644223:PAS chr4 0674
gene id: 644223:PAS_chr4_0674
uniprot id: C4R8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

644223:PAS chr2-1 0496
gene id: 644223:PAS_chr2-1_0496
uniprot id: C4R0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

644223:PAS chr4 0434
gene id: 644223:PAS_chr4_0434
uniprot id: C4R7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

644223:PAS chr4 0858
gene id: 644223:PAS_chr4_0858
uniprot id: C4R952
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr4 0800
gene id: 644223:PAS_chr4_0800
uniprot id: C4R8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

644223:PAS chr3 0690
gene id: 644223:PAS_chr3_0690
uniprot id: C4R5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

644223:PAS chr1-1 0404
gene id: 644223:PAS_chr1-1_0404
uniprot id: C4QX08
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0161
gene id: 644223:PAS_chr1-3_0161
uniprot id: C4QVE9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0214
gene id: 644223:PAS_chr3_0214
uniprot id: C4R3V7
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr3 0891
gene id: 644223:PAS_chr3_0891
uniprot id: C4R5W2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

644223:PAS chr1-4 0230
gene id: 644223:PAS_chr1-4_0230
uniprot id: C4QXU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

644223:PAS chr2-2 0068
gene id: 644223:PAS_chr2-2_0068
uniprot id: C4R2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

644223:PAS chr1-4 0395
gene id: 644223:PAS_chr1-4_0395
uniprot id: C4QYB7
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0782
gene id: 644223:PAS_chr3_0782
uniprot id: C4R5K1
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-1 0305
gene id: 644223:PAS_chr1-1_0305
uniprot id: C4QWQ9
names: Similarity
messages: Belongs to the Rho GDI family.

644223:PAS chr3 0972
gene id: 644223:PAS_chr3_0972
uniprot id: C4R650
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

644223:PAS chr2-2 0437
gene id: 644223:PAS_chr2-2_0437
uniprot id: C4R1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

644223:PAS chr1-1 0136
gene id: 644223:PAS_chr1-1_0136
uniprot id: C4QW77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

644223:PAS chr1-3 0034
gene id: 644223:PAS_chr1-3_0034
uniprot id: C4QV16
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

644223:PAS FragD 0014
gene id: 644223:PAS_FragD_0014
uniprot id: C4R9B9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

644223:PAS chr4 0807
gene id: 644223:PAS_chr4_0807
uniprot id: C4R902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

644223:PAS chr2-2 0099
gene id: 644223:PAS_chr2-2_0099
uniprot id: C4R2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

644223:PAS chr1-4 0050
gene id: 644223:PAS_chr1-4_0050
uniprot id: C4QXA8
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr4 0143
gene id: 644223:PAS_chr4_0143
uniprot id: C4R6Z4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0656
gene id: 644223:PAS_chr4_0656
uniprot id: C4R8I9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0749
gene id: 644223:PAS_chr4_0749
uniprot id: C4R8T6
names: Function
names: Subcellular Location Annotation
messages: May act as a zinc-influx transporter.
messages: Membrane

644223:PAS chr4 0330
gene id: 644223:PAS_chr4_0330
uniprot id: C4R7J7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

644223:PAS FragB 0039
gene id: 644223:PAS_FragB_0039
uniprot id: C4QZ97
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0219
gene id: 644223:PAS_chr1-4_0219
uniprot id: C4QXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

644223:PAS chr1-4 0124
gene id: 644223:PAS_chr1-4_0124
uniprot id: C4QXI0
names: Similarity
messages: Belongs to the NAD kinase family.

644223:PAS chr3 1133
gene id: 644223:PAS_chr3_1133
uniprot id: C4R367
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0648
gene id: 644223:PAS_chr4_0648
uniprot id: C4R8I1
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

644223:PAS chr1-3 0114
gene id: 644223:PAS_chr1-3_0114
uniprot id: C4QVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

644223:PAS chr2-2 0282
gene id: 644223:PAS_chr2-2_0282
uniprot id: C4R2A7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0369
gene id: 644223:PAS_chr1-1_0369
uniprot id: C4QWX3
names: Similarity
messages: Belongs to the IST1 family.

644223:PAS chr3 1145
gene id: 644223:PAS_chr3_1145
uniprot id: C4R3A8
names: Subcellular Location Annotation
messages: Cell surface

644223:PAS chr3 0386
gene id: 644223:PAS_chr3_0386
uniprot id: C4R4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

644223:PAS chr4 0677
gene id: 644223:PAS_chr4_0677
uniprot id: C4R8L1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr3 0278
gene id: 644223:PAS_chr3_0278
uniprot id: C4R431
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-1 0470
gene id: 644223:PAS_chr1-1_0470
uniprot id: C4QW10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEF1 family.
messages: RNA polymerase II degradation factor recruits the ubiquitination machinery to the RNA polymerase II for polyubiquitination, removal and degradation, when RAD26 fails to efficiently displace stalled RNA polymerase II. Also involved in telomere length regulation.
messages: telomere

644223:PAS chr4 0943
gene id: 644223:PAS_chr4_0943
uniprot id: C4R7H4
names: Disruption Phenotype
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Decreased growth on nutrient limitation and reduced cell flocculation compared to wild-type.
messages: Heterododecamer of 4 alpha, 4 beta and 4 gamma chains. The gamma chain bridges the N-terminal halves of the alpha and beta subunits (By similarity).
messages: Structural subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase. Not required for catalytic activity. Fine-tunes allosteric regulation of the ATP-PFK by ATP, fructose 2,6-bisphosphate and AMP (By similarity).
messages: This subunit is only found in some Pichia species.

644223:PAS chr1-3 0129
gene id: 644223:PAS_chr1-3_0129
uniprot id: C4QVB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

644223:PAS chr3 0665
gene id: 644223:PAS_chr3_0665
uniprot id: C4R576
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

644223:PAS chr1-4 0130
gene id: 644223:PAS_chr1-4_0130
uniprot id: C4QXI5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

644223:PAS chr1-4 0058
gene id: 644223:PAS_chr1-4_0058
uniprot id: C4QXB5
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

644223:PAS chr2-1 0874
gene id: 644223:PAS_chr2-1_0874
uniprot id: C4R1C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

644223:PAS chr2-1 0213
gene id: 644223:PAS_chr2-1_0213
uniprot id: C4QZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
messages: May be involved in the mitochondrial lipid metabolism.
messages: Mitochondrion

644223:PAS chr1-4 0151
gene id: 644223:PAS_chr1-4_0151
uniprot id: C4QXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

644223:PAS chr1-4 0602
gene id: 644223:PAS_chr1-4_0602
uniprot id: C4QYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

644223:PAS chr3 0450
gene id: 644223:PAS_chr3_0450
uniprot id: C4R4L1
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr3 0825
gene id: 644223:PAS_chr3_0825
uniprot id: C4R5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin NSP1/NUP62 family.
messages: Nucleus membrane

644223:PAS chr3 0916
gene id: 644223:PAS_chr3_0916
uniprot id: C4R5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

644223:PAS chr1-4 0537
gene id: 644223:PAS_chr1-4_0537
uniprot id: C4QYR7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

644223:PAS chr2-1 0407
gene id: 644223:PAS_chr2-1_0407
uniprot id: C4R0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

644223:PAS chr3 0728
gene id: 644223:PAS_chr3_0728
uniprot id: C4R5E1
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

644223:PAS chr2-1 0543
gene id: 644223:PAS_chr2-1_0543
uniprot id: C4R102
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

644223:PAS chr4 0517
gene id: 644223:PAS_chr4_0517
uniprot id: C4R847
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1027
gene id: 644223:PAS_chr3_1027
uniprot id: C4R6A4
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0061
gene id: 644223:PAS_chr2-2_0061
uniprot id: C4R2Z8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0670
gene id: 644223:PAS_chr1-4_0670
uniprot id: C4QY46
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr1-1 0006
gene id: 644223:PAS_chr1-1_0006
uniprot id: C4QVT6
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

644223:PAS chr3 1048
gene id: 644223:PAS_chr3_1048
uniprot id: C4R6C4
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

644223:PAS chr2-2 0167
gene id: 644223:PAS_chr2-2_0167
uniprot id: C4R2N3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

644223:PAS chr1-4 0029
gene id: 644223:PAS_chr1-4_0029
uniprot id: C4QX90
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

644223:PAS chr2-1 0280
gene id: 644223:PAS_chr2-1_0280
uniprot id: C4R070
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0175
gene id: 644223:PAS_chr3_0175
uniprot id: C4R3R7
names: Similarity
messages: Belongs to the peptidase M24 family.

644223:PAS chr1-4 0007
gene id: 644223:PAS_chr1-4_0007
uniprot id: C4QX67
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0163
gene id: 644223:PAS_chr4_0163
uniprot id: C4R714
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

644223:PAS chr1-4 0376
gene id: 644223:PAS_chr1-4_0376
uniprot id: C4QY98
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

644223:PAS chr3 0552
gene id: 644223:PAS_chr3_0552
uniprot id: C4R4W5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

644223:PAS chr1-1 0432
gene id: 644223:PAS_chr1-1_0432
uniprot id: C4QX36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

644223:PAS chr1-1 0088
gene id: 644223:PAS_chr1-1_0088
uniprot id: C4QW25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

644223:PAS chr4 0194
gene id: 644223:PAS_chr4_0194
uniprot id: C4R744
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

644223:PAS chr3 0383
gene id: 644223:PAS_chr3_0383
uniprot id: C4R4E2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0020
gene id: 644223:PAS_chr3_0020
uniprot id: C4R3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

644223:PAS chr2-1 0419
gene id: 644223:PAS_chr2-1_0419
uniprot id: C4R0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS FragD 0011
gene id: 644223:PAS_FragD_0011
uniprot id: C4R9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

644223:PAS chr1-4 0452
gene id: 644223:PAS_chr1-4_0452
uniprot id: C4QYI0
names: Similarity
messages: Belongs to the SEC6 family.

644223:PAS chr4 0411
gene id: 644223:PAS_chr4_0411
uniprot id: C4R7T5
names: Similarity
messages: Belongs to the SIP5 family.

644223:PAS chr2-1 0149
gene id: 644223:PAS_chr2-1_0149
uniprot id: C4QZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

644223:PAS chr3 0846
gene id: 644223:PAS_chr3_0846
uniprot id: C4R5R1
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

644223:PAS chr3 0813
gene id: 644223:PAS_chr3_0813
uniprot id: C4R5N0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX4 family.
messages: Forms a heterodimer with SLX1.
messages: Nucleus
messages: Phosphorylated in response to DNA damage.
messages: Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (By similarity).

644223:PAS chr4 0028
gene id: 644223:PAS_chr4_0028
uniprot id: C4R6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

644223:PAS chr4 0172
gene id: 644223:PAS_chr4_0172
uniprot id: C4R722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

644223:PAS chr2-2 0024
gene id: 644223:PAS_chr2-2_0024
uniprot id: C4R339
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

644223:PAS chr1-1 0153
gene id: 644223:PAS_chr1-1_0153
uniprot id: C4QW94
names: Similarity
messages: Belongs to the PPP phosphatase family.

644223:PAS chr4 0308
gene id: 644223:PAS_chr4_0308
uniprot id: C4R7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.

644223:PAS chr1-4 0317
gene id: 644223:PAS_chr1-4_0317
uniprot id: C4QY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

644223:PAS chr3 0511
gene id: 644223:PAS_chr3_0511
uniprot id: C4R4S4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0248
gene id: 644223:PAS_chr4_0248
uniprot id: C4R7A4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr1-3 0030
gene id: 644223:PAS_chr1-3_0030
uniprot id: C4QV12
names: Similarity
messages: Belongs to the activator 1 small subunits family.

644223:PAS chr4 0472
gene id: 644223:PAS_chr4_0472
uniprot id: C4R7Z9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-3 0250
gene id: 644223:PAS_chr1-3_0250
uniprot id: C4QVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr1-3 0084
gene id: 644223:PAS_chr1-3_0084
uniprot id: C4QV67
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0489
gene id: 644223:PAS_chr2-1_0489
uniprot id: C4R0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0302
gene id: 644223:PAS_chr2-1_0302
uniprot id: C4R092
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

644223:PAS chr2-1 0497
gene id: 644223:PAS_chr2-1_0497
uniprot id: C4R0V3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

644223:PAS FragB 0025
gene id: 644223:PAS_FragB_0025
uniprot id: C4QZ81
names: Similarity
messages: Belongs to the PhyH family.

644223:PAS chr4 0195
gene id: 644223:PAS_chr4_0195
uniprot id: C4R745
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

644223:PAS chr4 0643
gene id: 644223:PAS_chr4_0643
uniprot id: C4R8H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 45 (cellulase K) family.

644223:PAS chr1-3 0162
gene id: 644223:PAS_chr1-3_0162
uniprot id: C4QVF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

644223:PAS chr3 1064
gene id: 644223:PAS_chr3_1064
uniprot id: C4R6E1
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

644223:PAS chr4 0516
gene id: 644223:PAS_chr4_0516
uniprot id: C4R846
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644223:PAS chr2-2 0186
gene id: 644223:PAS_chr2-2_0186
uniprot id: C4R2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

644223:PAS chr2-1 0311
gene id: 644223:PAS_chr2-1_0311
uniprot id: C4R0A2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

644223:PAS chr2-2 0496
gene id: 644223:PAS_chr2-2_0496
uniprot id: C4R1X5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644223:PAS chr1-1 0166
gene id: 644223:PAS_chr1-1_0166
uniprot id: C4QWA8
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

644223:PAS chr2-2 0173
gene id: 644223:PAS_chr2-2_0173
uniprot id: C4R2M6
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1191
gene id: 644223:PAS_chr3_1191
uniprot id: C4R4L8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-3 0038
gene id: 644223:PAS_chr1-3_0038
uniprot id: C4QV19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0406
gene id: 644223:PAS_chr1-4_0406
uniprot id: C4QYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

644223:PAS chr3 0266
gene id: 644223:PAS_chr3_0266
uniprot id: C4R418
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0012
gene id: 644223:PAS_chr1-4_0012
uniprot id: C4QX73
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0193
gene id: 644223:PAS_chr2-2_0193
uniprot id: C4R2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

644223:PAS chr3 1069
gene id: 644223:PAS_chr3_1069
uniprot id: C4R6E6
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

644223:PAS FragB 0036
gene id: 644223:PAS_FragB_0036
uniprot id: C4QZ92
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

644223:PAS chr4 0134
gene id: 644223:PAS_chr4_0134
uniprot id: C4R6Y6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

644223:PAS chr3 0683
gene id: 644223:PAS_chr3_0683
uniprot id: C4R596
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr2-2 0165
gene id: 644223:PAS_chr2-2_0165
uniprot id: C4R2N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

644223:PAS chr1-1 0176
gene id: 644223:PAS_chr1-1_0176
uniprot id: C4QWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

644223:PAS chr1-1 0381
gene id: 644223:PAS_chr1-1_0381
uniprot id: C4QWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

644223:PAS c131 0017
gene id: 644223:PAS_c131_0017
uniprot id: C4R395
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

644223:PAS chr3 0419
gene id: 644223:PAS_chr3_0419
uniprot id: C4R4I2
names: Similarity
messages: Belongs to the peptidase M14 family.

644223:PAS chr4 0186
gene id: 644223:PAS_chr4_0186
uniprot id: C4R737
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0042
gene id: 644223:PAS_chr1-4_0042
uniprot id: C4QXA0
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

644223:PAS chr1-1 0244
gene id: 644223:PAS_chr1-1_0244
uniprot id: C4QWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

644223:PAS chr2-2 0182
gene id: 644223:PAS_chr2-2_0182
uniprot id: C4R2L4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

644223:PAS chr1-1 0483
gene id: 644223:PAS_chr1-1_0483
uniprot id: C4QWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

644223:PAS chr1-4 0659
gene id: 644223:PAS_chr1-4_0659
uniprot id: C4QXN4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

644223:PAS chr2-2 0029
gene id: 644223:PAS_chr2-2_0029
uniprot id: C4R333
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

644223:PAS chr2-1 0273
gene id: 644223:PAS_chr2-1_0273
uniprot id: C4R063
names: Similarity
messages: Belongs to the pyridoxine kinase family.

644223:PAS chr1-3 0102
gene id: 644223:PAS_chr1-3_0102
uniprot id: C4QV89
names: Similarity
messages: Belongs to the ClpA/ClpB family.

644223:PAS chr1-4 0545
gene id: 644223:PAS_chr1-4_0545
uniprot id: C4QYS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-2 0216
gene id: 644223:PAS_chr2-2_0216
uniprot id: C4R2H7
names: Similarity
messages: Belongs to the PP2C family.

644223:PAS chr2-2 0111
gene id: 644223:PAS_chr2-2_0111
uniprot id: C4R2U1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

644223:PAS chr4 0055
gene id: 644223:PAS_chr4_0055
uniprot id: C4R6Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0228
gene id: 644223:PAS_chr1-4_0228
uniprot id: C4QXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

644223:PAS FragD 0019
gene id: 644223:PAS_FragD_0019
uniprot id: C4R9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

644223:PAS chr4 0022
gene id: 644223:PAS_chr4_0022
uniprot id: C4R6M4
names: Similarity
messages: Belongs to the peptidase C19 family.

644223:PAS chr4 0785
gene id: 644223:PAS_chr4_0785
uniprot id: C4R8X6
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

644223:PAS chr1-3 0191
gene id: 644223:PAS_chr1-3_0191
uniprot id: C4QVI1
names: Subunit
messages: Homodimer.

644223:PAS chr1-4 0401
gene id: 644223:PAS_chr1-4_0401
uniprot id: C4QYC6
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0175
gene id: 644223:PAS_chr2-2_0175
uniprot id: C4R2M3
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

644223:PAS chr2-1 0228
gene id: 644223:PAS_chr2-1_0228
uniprot id: C4R014
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

644223:PAS chr2-2 0456
gene id: 644223:PAS_chr2-2_0456
uniprot id: C4R2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

644223:PAS chr2-1 0763
gene id: 644223:PAS_chr2-1_0763
uniprot id: C4R1P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

644223:PAS chr4 0645
gene id: 644223:PAS_chr4_0645
uniprot id: C4R8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

644223:PAS chr3 1103
gene id: 644223:PAS_chr3_1103
uniprot id: C4R6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

644223:PAS chr1-4 0637
gene id: 644223:PAS_chr1-4_0637
uniprot id: C4QZ24
names: Similarity
messages: Belongs to the KTI12 family.

644223:PAS chr3 0291
gene id: 644223:PAS_chr3_0291
uniprot id: C4R445
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0615
gene id: 644223:PAS_chr2-1_0615
uniprot id: C4R181
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

644223:PAS chr4 0030
gene id: 644223:PAS_chr4_0030
uniprot id: C4R6N1
names: Subcellular Location Annotation
messages: nucleolus

644223:PAS chr1-4 0216
gene id: 644223:PAS_chr1-4_0216
uniprot id: C4QXS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

644223:PAS chr2-2 0059
gene id: 644223:PAS_chr2-2_0059
uniprot id: C4R300
names: Similarity
messages: Belongs to the NDK family.

644223:PAS chr2-1 0781
gene id: 644223:PAS_chr2-1_0781
uniprot id: C4R1R4
names: Similarity
messages: Belongs to the UTP6 family.

644223:PAS chr3 0836
gene id: 644223:PAS_chr3_0836
uniprot id: C4R5Q1
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr3 0956
gene id: 644223:PAS_chr3_0956
uniprot id: C4R631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm

644223:PAS chr2-2 0283
gene id: 644223:PAS_chr2-2_0283
uniprot id: C4R2A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0287
gene id: 644223:PAS_chr4_0287
uniprot id: C4R7E9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0567
gene id: 644223:PAS_chr1-4_0567
uniprot id: C4QYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

644223:PAS chr1-3 0277
gene id: 644223:PAS_chr1-3_0277
uniprot id: C4QVR9
names: Function
names: Similarity
messages: Belongs to the IRC19 family.
messages: Involved in sporulation and maintenance of the mitochondrial DNA. Is probably involved in a pathway contributing to genomic integrity (By similarity).

644223:PAS chr4 0238
gene id: 644223:PAS_chr4_0238
uniprot id: C4R792
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

644223:PAS chr3 1108
gene id: 644223:PAS_chr3_1108
uniprot id: C4R6I9
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1002
gene id: 644223:PAS_chr3_1002
uniprot id: C4R678
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

644223:PAS chr2-1 0145
gene id: 644223:PAS_chr2-1_0145
uniprot id: C4QZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

644223:PAS chr3 0929
gene id: 644223:PAS_chr3_0929
uniprot id: C4R603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

644223:PAS chr2-2 0352
gene id: 644223:PAS_chr2-2_0352
uniprot id: C4R229
names: Similarity
messages: Belongs to the LSM12 family.

644223:PAS chr2-1 0093
gene id: 644223:PAS_chr2-1_0093
uniprot id: C4QZM0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

644223:PAS chr3 0519
gene id: 644223:PAS_chr3_0519
uniprot id: C4R4T2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 0738
gene id: 644223:PAS_chr3_0738
uniprot id: C4R5F2
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr4 0875
gene id: 644223:PAS_chr4_0875
uniprot id: C4R970
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat ASA1 family.
messages: Component of the ASTRA chromatin remodeling machinery complex.
messages: Component of the ASTRA complex involved in chromatin remodeling.
messages: Nucleus

644223:PAS chr1-3 0197
gene id: 644223:PAS_chr1-3_0197
uniprot id: C4QVI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

644223:PAS chr1-4 0003
gene id: 644223:PAS_chr1-4_0003
uniprot id: C4QX63
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

644223:PAS chr3 1129
gene id: 644223:PAS_chr3_1129
uniprot id: C4R362
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr1-4 0357
gene id: 644223:PAS_chr1-4_0357
uniprot id: C4QY77
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr3 0157
gene id: 644223:PAS_chr3_0157
uniprot id: C4R3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr2-2 0355
gene id: 644223:PAS_chr2-2_0355
uniprot id: C4R226
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr2-2 0201
gene id: 644223:PAS_chr2-2_0201
uniprot id: C4R2J5
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

644223:PAS chr2-1 0483
gene id: 644223:PAS_chr2-1_0483
uniprot id: C4R0T9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

644223:PAS chr4 0249
gene id: 644223:PAS_chr4_0249
uniprot id: C4R7A5
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

644223:PAS chr1-3 0248
gene id: 644223:PAS_chr1-3_0248
uniprot id: C4QVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

644223:PAS chr4 0181
gene id: 644223:PAS_chr4_0181
uniprot id: C4R733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

644223:PAS chr4 0408
gene id: 644223:PAS_chr4_0408
uniprot id: C4R7T2
names: Similarity
messages: Belongs to the cytidylyltransferase family.

644223:PAS chr4 0157
gene id: 644223:PAS_chr4_0157
uniprot id: C4R707
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

644223:PAS chr2-1 0122
gene id: 644223:PAS_chr2-1_0122
uniprot id: C4QZQ2
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

644223:PAS chr3 0997
gene id: 644223:PAS_chr3_0997
uniprot id: C4R673
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0551
gene id: 644223:PAS_chr2-1_0551
uniprot id: C4R111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

644223:PAS chr4 0459
gene id: 644223:PAS_chr4_0459
uniprot id: C4R7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

644223:PAS chr4 0450
gene id: 644223:PAS_chr4_0450
uniprot id: C4R7X8
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT family.
messages: Beta-mannosyltransferase involved in cell wall biosynthesis. Initiates the beta-mannosylation of core N-linked glycans.
messages: Membrane
messages: Strongly reduces de degree of mannosylation of the core glycans and eliminates glycans resistant to alpha-1,2-mannosidase treatment.

644223:PAS chr2-1 0672
gene id: 644223:PAS_chr2-1_0672
uniprot id: C4R1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

644223:PAS chr4 0735
gene id: 644223:PAS_chr4_0735
uniprot id: C4R8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

644223:PAS chr4 0782
gene id: 644223:PAS_chr4_0782
uniprot id: C4R8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

644223:PAS chr2-1 0584
gene id: 644223:PAS_chr2-1_0584
uniprot id: C4R146
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

644223:PAS chr3 0107
gene id: 644223:PAS_chr3_0107
uniprot id: C4R3K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

644223:PAS chr2-1 0396
gene id: 644223:PAS_chr2-1_0396
uniprot id: C4R0J3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr2-1 0285
gene id: 644223:PAS_chr2-1_0285
uniprot id: C4R075
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

644223:PAS chr1-3 0059
gene id: 644223:PAS_chr1-3_0059
uniprot id: C4QV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644223:PAS chr4 0013
gene id: 644223:PAS_chr4_0013
uniprot id: C4R6L7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

644223:PAS chr1-4 0037
gene id: 644223:PAS_chr1-4_0037
uniprot id: C4QX95
names: Similarity
messages: Belongs to the MNN1/MNT family.

644223:PAS chr1-4 0238
gene id: 644223:PAS_chr1-4_0238
uniprot id: C4QXV0
names: Similarity
messages: Belongs to the RutC family.

644223:PAS chr2-2 0252
gene id: 644223:PAS_chr2-2_0252
uniprot id: C4R2D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

644223:PAS chr2-1 0619
gene id: 644223:PAS_chr2-1_0619
uniprot id: C4R185
names: Similarity
messages: Belongs to the activator 1 small subunits family.

644223:PAS chr4 0105
gene id: 644223:PAS_chr4_0105
uniprot id: C4R6V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS chr1-1 0353
gene id: 644223:PAS_chr1-1_0353
uniprot id: C4QWV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

644223:PAS chr2-1 0502
gene id: 644223:PAS_chr2-1_0502
uniprot id: C4R0V9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

644223:PAS chr1-4 0244
gene id: 644223:PAS_chr1-4_0244
uniprot id: C4QXV6
names: Similarity
messages: Belongs to the epsin family.

644223:PAS chr2-2 0005
gene id: 644223:PAS_chr2-2_0005
uniprot id: C4R357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

644223:PAS chr1-3 0247
gene id: 644223:PAS_chr1-3_0247
uniprot id: C4QVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

644223:PAS chr1-4 0646
gene id: 644223:PAS_chr1-4_0646
uniprot id: C4QZ34
names: Similarity
messages: Belongs to the OSBP family.

644223:PAS chr3 0158
gene id: 644223:PAS_chr3_0158
uniprot id: C4R3P9
names: Similarity
messages: Belongs to the WD repeat WDR48 family.

644223:PAS chr1-4 0100
gene id: 644223:PAS_chr1-4_0100
uniprot id: C4QXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

644223:PAS chr1-1 0129
gene id: 644223:PAS_chr1-1_0129
uniprot id: C4QW69
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

644223:PAS chr2-2 0161
gene id: 644223:PAS_chr2-2_0161
uniprot id: C4R2P0
names: Subcellular Location Annotation
messages: Membrane

644223:PAS FragD 0015
gene id: 644223:PAS_FragD_0015
uniprot id: C4R9B8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

644223:PAS chr2-1 0464
gene id: 644223:PAS_chr2-1_0464
uniprot id: C4R0R8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

644223:PAS chr3 0453
gene id: 644223:PAS_chr3_0453
uniprot id: C4R4L4
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

644223:PAS chr2-2 0251
gene id: 644223:PAS_chr2-2_0251
uniprot id: C4R2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus

644223:PAS chr2-2 0150
gene id: 644223:PAS_chr2-2_0150
uniprot id: C4R2Q2
names: Similarity
messages: Belongs to the WD repeat LST8 family.

644223:PAS c121 0006
gene id: 644223:PAS_c121_0006
uniprot id: C4QZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

644223:PAS chr2-1 0684
gene id: 644223:PAS_chr2-1_0684
uniprot id: C4R1F7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

644223:PAS chr1-4 0458
gene id: 644223:PAS_chr1-4_0458
uniprot id: C4QYI7
names: Similarity
messages: Belongs to the IlvD/Edd family.

644223:PAS chr3 0285
gene id: 644223:PAS_chr3_0285
uniprot id: C4R439
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

644223:PAS chr2-2 0325
gene id: 644223:PAS_chr2-2_0325
uniprot id: C4R257
names: Subcellular Location Annotation
messages: nuclear pore complex

644223:PAS chr4 0253
gene id: 644223:PAS_chr4_0253
uniprot id: C4R7A9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

644223:PAS chr3 0803
gene id: 644223:PAS_chr3_0803
uniprot id: C4R5M0
names: Similarity
messages: Belongs to the peptidase M18 family.

644223:PAS chr2-2 0257
gene id: 644223:PAS_chr2-2_0257
uniprot id: C4R2D3
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

644223:PAS chr2-1 0204
gene id: 644223:PAS_chr2-1_0204
uniprot id: C4QZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

644223:PAS chr2-2 0377
gene id: 644223:PAS_chr2-2_0377
uniprot id: C4R204
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

644223:PAS chr4 0011
gene id: 644223:PAS_chr4_0011
uniprot id: C4R6L5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

644223:PAS chr4 0524
gene id: 644223:PAS_chr4_0524
uniprot id: C4R853
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

644223:PAS chr2-2 0041
gene id: 644223:PAS_chr2-2_0041
uniprot id: C4R319
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

644223:PAS chr1-4 0383
gene id: 644223:PAS_chr1-4_0383
uniprot id: C4QYA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

644223:PAS chr1-4 0461
gene id: 644223:PAS_chr1-4_0461
uniprot id: C4QYJ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr2-1 0427
gene id: 644223:PAS_chr2-1_0427
uniprot id: C4R0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

644223:PAS chr1-4 0121
gene id: 644223:PAS_chr1-4_0121
uniprot id: C4QXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

644223:PAS chr1-1 0189
gene id: 644223:PAS_chr1-1_0189
uniprot id: C4QWD2
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

644223:PAS chr3 0052
gene id: 644223:PAS_chr3_0052
uniprot id: C4R3E5
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

644223:PAS chr3 1034
gene id: 644223:PAS_chr3_1034
uniprot id: C4R6B1
names: Similarity
messages: Belongs to the CCDC124 family.

644223:PAS chr1-4 0487
gene id: 644223:PAS_chr1-4_0487
uniprot id: C4QYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

644223:PAS chr2-2 0086
gene id: 644223:PAS_chr2-2_0086
uniprot id: C4R2W8
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

644223:PAS chr3 0716
gene id: 644223:PAS_chr3_0716
uniprot id: C4R5D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

644223:PAS chr2-2 0384
gene id: 644223:PAS_chr2-2_0384
uniprot id: C4R1Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

644223:PAS chr2-1 0549
gene id: 644223:PAS_chr2-1_0549
uniprot id: C4R109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-1 0335
gene id: 644223:PAS_chr1-1_0335
uniprot id: C4QWT9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

644223:PAS chr1-4 0513
gene id: 644223:PAS_chr1-4_0513
uniprot id: C4QYP1
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

644223:PAS chr2-2 0280
gene id: 644223:PAS_chr2-2_0280
uniprot id: C4R2A8
names: Similarity
messages: Belongs to the type-1 OGG1 family.

644223:PAS chr4 0322
gene id: 644223:PAS_chr4_0322
uniprot id: C4R7J0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

644223:PAS chr3 0349
gene id: 644223:PAS_chr3_0349
uniprot id: C4R4A4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644223:PAS chr1-1 0250
gene id: 644223:PAS_chr1-1_0250
uniprot id: C4QWJ7
names: Similarity
messages: Belongs to the COG4 family.

644223:PAS chr3 0571
gene id: 644223:PAS_chr3_0571
uniprot id: C4R4Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

644223:PAS chr1-4 0324
gene id: 644223:PAS_chr1-4_0324
uniprot id: C4QY42
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

644223:PAS chr3 1187
gene id: 644223:PAS_chr3_1187
uniprot id: C4R4F9
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr3 0895
gene id: 644223:PAS_chr3_0895
uniprot id: C4R5W6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

644223:PAS chr3 1040
gene id: 644223:PAS_chr3_1040
uniprot id: C4R6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

644223:PAS chr3 0269
gene id: 644223:PAS_chr3_0269
uniprot id: C4R422
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Required for vacuolar protein sorting.

644223:PAS chr4 0403
gene id: 644223:PAS_chr4_0403
uniprot id: C4R7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WRB/GET1 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

644223:PAS chr1-4 0465
gene id: 644223:PAS_chr1-4_0465
uniprot id: C4QYJ4
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

644223:PAS FragB 0056
gene id: 644223:PAS_FragB_0056
uniprot id: C4QZB4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

644223:PAS chr1-4 0086
gene id: 644223:PAS_chr1-4_0086
uniprot id: C4QXE2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0343
gene id: 644223:PAS_chr1-4_0343
uniprot id: C4QY63
names: Similarity
messages: Belongs to the CWC22 family.

644223:PAS chr2-1 0550
gene id: 644223:PAS_chr2-1_0550
uniprot id: C4R110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

644223:PAS chr3 1026
gene id: 644223:PAS_chr3_1026
uniprot id: C4R6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

644223:PAS chr1-3 0055
gene id: 644223:PAS_chr1-3_0055
uniprot id: C4QV37
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

644223:PAS chr1-1 0219
gene id: 644223:PAS_chr1-1_0219
uniprot id: C4QWG6
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

644223:PAS chr3 1230
gene id: 644223:PAS_chr3_1230
uniprot id: C4R5T1
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Acts as the peroxisome receptor for pexophagy. Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways. Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole.
messages: Interacts with ATG11, ATG17, ATG37, PEX3 and PEX14.
messages: Peroxisome membrane
messages: Phosphorylation at Ser-112 is required for micro- and macropexophagy.
messages: Preautophagosomal structure
messages: Vacuole lumen

644223:PAS chr1-4 0014
gene id: 644223:PAS_chr1-4_0014
uniprot id: C4QX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.

644223:PAS chr2-2 0122
gene id: 644223:PAS_chr2-2_0122
uniprot id: C4R2T0
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

644223:PAS chr3 1176
gene id: 644223:PAS_chr3_1176
uniprot id: C4R448
names: Similarity
messages: Belongs to the LTV1 family.

644223:PAS chr2-2 0274
gene id: 644223:PAS_chr2-2_0274
uniprot id: C4R2B5
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

644223:PAS chr2-1 0090
gene id: 644223:PAS_chr2-1_0090
uniprot id: C4QZL7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

644223:PAS chr4 0596
gene id: 644223:PAS_chr4_0596
uniprot id: C4R8D1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr3 1042
gene id: 644223:PAS_chr3_1042
uniprot id: C4R6B9
names: Similarity
messages: Belongs to the RNR ribonuclease family.

644223:PAS chr2-1 0885
gene id: 644223:PAS_chr2-1_0885
uniprot id: C4R1N9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

644223:PAS chr4 0285
gene id: 644223:PAS_chr4_0285
uniprot id: C4R7E7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

644223:PAS chr4 0747
gene id: 644223:PAS_chr4_0747
uniprot id: C4R8T4
names: Similarity
messages: Belongs to the NOP10 family.

644223:PAS chr2-1 0752
gene id: 644223:PAS_chr2-1_0752
uniprot id: C4R1M9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

644223:PAS chr2-1 0281
gene id: 644223:PAS_chr2-1_0281
uniprot id: C4R071
names: Similarity
messages: Belongs to the ELP6 family.

644223:PAS chr1-4 0218
gene id: 644223:PAS_chr1-4_0218
uniprot id: C4QXT0
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

644223:PAS chr2-1 0234
gene id: 644223:PAS_chr2-1_0234
uniprot id: C4R020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

644223:PAS chr4 0809
gene id: 644223:PAS_chr4_0809
uniprot id: C4R905
names: Similarity
messages: Belongs to the FAM214 family.

644223:PAS chr3 1015
gene id: 644223:PAS_chr3_1015
uniprot id: C4R690
names: Similarity
messages: Belongs to the MGR2 family.

644223:PAS chr1-1 0232
gene id: 644223:PAS_chr1-1_0232
uniprot id: C4QWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

644223:PAS chr2-2 0176
gene id: 644223:PAS_chr2-2_0176
uniprot id: C4R2M1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0801
gene id: 644223:PAS_chr2-1_0801
uniprot id: C4R1T6
names: Similarity
messages: Belongs to the protein kinase superfamily.

644223:PAS chr4 0657
gene id: 644223:PAS_chr4_0657
uniprot id: C4R8J0
names: Subcellular Location Annotation
messages: nuclear pore complex

644223:PAS chr2-1 0088
gene id: 644223:PAS_chr2-1_0088
uniprot id: C4QZL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644223:PAS chr2-2 0329
gene id: 644223:PAS_chr2-2_0329
uniprot id: C4R253
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

644223:PAS chr1-4 0358
gene id: 644223:PAS_chr1-4_0358
uniprot id: C4QY78
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

644223:PAS chr3 0381
gene id: 644223:PAS_chr3_0381
uniprot id: C4R4E0
names: Similarity
messages: Belongs to the OMP decarboxylase family.

644223:PAS chr3 0821
gene id: 644223:PAS_chr3_0821
uniprot id: C4R5N7
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0186
gene id: 644223:PAS_chr2-1_0186
uniprot id: C4QZX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

644223:PAS chr4 0259
gene id: 644223:PAS_chr4_0259
uniprot id: C4R7B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

644223:PAS chr1-4 0143
gene id: 644223:PAS_chr1-4_0143
uniprot id: C4QXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

644223:PAS chr3 0123
gene id: 644223:PAS_chr3_0123
uniprot id: C4R3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr2-1 0293
gene id: 644223:PAS_chr2-1_0293
uniprot id: C4R082
names: Similarity
messages: Belongs to the UPF0047 family.

644223:PAS chr4 0435
gene id: 644223:PAS_chr4_0435
uniprot id: C4R7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

644223:PAS chr1-4 0681
gene id: 644223:PAS_chr1-4_0681
uniprot id: C4QYG5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

644223:PAS chr1-4 0420
gene id: 644223:PAS_chr1-4_0420
uniprot id: C4QYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr3 0198
gene id: 644223:PAS_chr3_0198
uniprot id: C4R3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

644223:PAS chr2-1 0500
gene id: 644223:PAS_chr2-1_0500
uniprot id: C4R0V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

644223:PAS chr1-1 0020
gene id: 644223:PAS_chr1-1_0020
uniprot id: C4QVV0
names: Function
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

644223:PAS chr1-3 0210
gene id: 644223:PAS_chr1-3_0210
uniprot id: C4QVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Mitochondrion inner membrane

644223:PAS chr4 0270
gene id: 644223:PAS_chr4_0270
uniprot id: C4R7C9
names: Similarity
messages: Belongs to the AAA ATPase family.

644223:PAS chr1-1 0107
gene id: 644223:PAS_chr1-1_0107
uniprot id: C4QW46
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

644223:PAS chr3 1159
gene id: 644223:PAS_chr3_1159
uniprot id: C4R3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

644223:PAS chr1-3 0057
gene id: 644223:PAS_chr1-3_0057
uniprot id: P53024
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
messages: Endoplasmic reticulum membrane
messages: The COPII coat is composed of at least 5 proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1. Component of the nuclear pore complex (NPC). NPC constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. Due to its 8-fold rotational symmetry, all subunits are present with 8 copies or multiples thereof.
messages: nuclear pore complex

644223:PAS chr3 0737
gene id: 644223:PAS_chr3_0737
uniprot id: C4R5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

644223:PAS chr3 0353
gene id: 644223:PAS_chr3_0353
uniprot id: C4R4A9
names: Similarity
messages: Belongs to the yippee family.

644223:PAS chr1-3 0036
gene id: 644223:PAS_chr1-3_0036
uniprot id: C4QV17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERT1/acuK family.
messages: Nucleus
messages: Transcription factor which regulates nonfermentable carbon utilization.

644223:PAS chr2-1 0645
gene id: 644223:PAS_chr2-1_0645
uniprot id: C4R1B5
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0160
gene id: 644223:PAS_chr1-4_0160
uniprot id: C4QXL7
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

644223:PAS chr3 0848
gene id: 644223:PAS_chr3_0848
uniprot id: C4R5R3
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0235
gene id: 644223:PAS_chr2-1_0235
uniprot id: C4R021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

644223:PAS chr2-1 0037
gene id: 644223:PAS_chr2-1_0037
uniprot id: C4QZG3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

644223:PAS chr1-4 0468
gene id: 644223:PAS_chr1-4_0468
uniprot id: C4QYJ7
names: Similarity
messages: Belongs to the peptidase M24B family.

644223:PAS chr3 0993
gene id: 644223:PAS_chr3_0993
uniprot id: C4R669
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

644223:PAS chr3 0701
gene id: 644223:PAS_chr3_0701
uniprot id: C4R5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

644223:PAS chr2-1 0173
gene id: 644223:PAS_chr2-1_0173
uniprot id: C4QZV6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

644223:PAS chr3 0171
gene id: 644223:PAS_chr3_0171
uniprot id: C4R3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

644223:PAS chr2-2 0402
gene id: 644223:PAS_chr2-2_0402
uniprot id: C4R1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

644223:PAS chr2-2 0385
gene id: 644223:PAS_chr2-2_0385
uniprot id: C4R1Z6
names: Subcellular Location Annotation
messages: nuclear pore complex

644223:PAS chr3 0424
gene id: 644223:PAS_chr3_0424
uniprot id: C4R4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0510
gene id: 644223:PAS_chr4_0510
uniprot id: C4R840
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

644223:PAS chr1-1 0401
gene id: 644223:PAS_chr1-1_0401
uniprot id: C4QX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

644223:PAS chr4 0460
gene id: 644223:PAS_chr4_0460
uniprot id: C4R7Y8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

644223:PAS chr3 0226
gene id: 644223:PAS_chr3_0226
uniprot id: C4R3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS FragD 0007
gene id: 644223:PAS_FragD_0007
uniprot id: C4R9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

644223:PAS chr2-1 0644
gene id: 644223:PAS_chr2-1_0644
uniprot id: Q9P4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

644223:PAS chr3 0636
gene id: 644223:PAS_chr3_0636
uniprot id: C4R549
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

644223:PAS chr1-4 0542
gene id: 644223:PAS_chr1-4_0542
uniprot id: C4QYS3
names: Function
names: Similarity
messages: Belongs to the RRG8 family.
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

644223:PAS chr3 0659
gene id: 644223:PAS_chr3_0659
uniprot id: C4R570
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

644223:PAS chr2-2 0160
gene id: 644223:PAS_chr2-2_0160
uniprot id: C4R2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

644223:PAS chr3 1104
gene id: 644223:PAS_chr3_1104
uniprot id: C4R6I4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0300
gene id: 644223:PAS_chr1-4_0300
uniprot id: C4QY17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

644223:PAS chr3 1181
gene id: 644223:PAS_chr3_1181
uniprot id: C4R4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

644223:PAS chr2-1 0350
gene id: 644223:PAS_chr2-1_0350
uniprot id: C4R0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

644223:PAS chr3 0230
gene id: 644223:PAS_chr3_0230
uniprot id: C4R3X8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

644223:PAS FragB 0046
gene id: 644223:PAS_FragB_0046
uniprot id: C4QZA5
names: Similarity
messages: Belongs to the cyclin family.

644223:PAS chr2-1 0694
gene id: 644223:PAS_chr2-1_0694
uniprot id: C4R1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Nucleus

644223:PAS chr4 0606
gene id: 644223:PAS_chr4_0606
uniprot id: C4R8E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

644223:PAS chr1-4 0427
gene id: 644223:PAS_chr1-4_0427
uniprot id: C4QYF4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

644223:PAS chr1-1 0044
gene id: 644223:PAS_chr1-1_0044
uniprot id: C4QVX9
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

644223:PAS chr3 1085
gene id: 644223:PAS_chr3_1085
uniprot id: C4R6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

644223:PAS chr3 0662
gene id: 644223:PAS_chr3_0662
uniprot id: C4R573
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0484
gene id: 644223:PAS_chr2-1_0484
uniprot id: C4R0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

644223:PAS chr1-1 0224
gene id: 644223:PAS_chr1-1_0224
uniprot id: C4QWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

644223:PAS chr2-1 0142
gene id: 644223:PAS_chr2-1_0142
uniprot id: C4QZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

644223:PAS chr3 0995
gene id: 644223:PAS_chr3_0995
uniprot id: C4R671
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

644223:PAS chr2-2 0233
gene id: 644223:PAS_chr2-2_0233
uniprot id: C4R2F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

644223:PAS chr4 0522
gene id: 644223:PAS_chr4_0522
uniprot id: C4R852
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

644223:PAS chr2-2 0345
gene id: 644223:PAS_chr2-2_0345
uniprot id: C4R237
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

644223:PAS chr3 0454
gene id: 644223:PAS_chr3_0454
uniprot id: C4R4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

644223:PAS chr2-1 0167
gene id: 644223:PAS_chr2-1_0167
uniprot id: C4QZU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

644223:PAS chr2-1 0486
gene id: 644223:PAS_chr2-1_0486
uniprot id: C4R0U2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

644223:PAS chr3 0023
gene id: 644223:PAS_chr3_0023
uniprot id: C4R3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

644223:PAS chr2-1 0890
gene id: 644223:PAS_chr2-1_0890
uniprot id: C4R1R6
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

644223:PAS chr2-1 0444
gene id: 644223:PAS_chr2-1_0444
uniprot id: C4R0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

644223:PAS chr1-1 0055
gene id: 644223:PAS_chr1-1_0055
uniprot id: C4QVZ0
names: Similarity
messages: Belongs to the UFD1 family.

644223:PAS chr4 0726
gene id: 644223:PAS_chr4_0726
uniprot id: C4R8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

644223:PAS chr3 0262
gene id: 644223:PAS_chr3_0262
uniprot id: C4R413
names: Similarity
messages: Belongs to the thymidylate kinase family.

644223:PAS chr4 0727
gene id: 644223:PAS_chr4_0727
uniprot id: C4R8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

644223:PAS chr4 0880
gene id: 644223:PAS_chr4_0880
uniprot id: C4R976
names: Similarity
messages: Belongs to the SUI1 family.

644223:PAS chr3 0994
gene id: 644223:PAS_chr3_0994
uniprot id: C4R670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

644223:PAS chr2-1 0360
gene id: 644223:PAS_chr2-1_0360
uniprot id: C4R0F6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

644223:PAS chr1-1 0393
gene id: 644223:PAS_chr1-1_0393
uniprot id: C4QWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chitin synthase family.
messages: Cell membrane
messages: Membrane
messages: Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

644223:PAS chr3 1238
gene id: 644223:PAS_chr3_1238
uniprot id: C4R5Z2
names: Similarity
messages: Belongs to the syntaxin family.

644223:PAS chr4 0073
gene id: 644223:PAS_chr4_0073
uniprot id: C4R6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

644223:PAS chr3 0111
gene id: 644223:PAS_chr3_0111
uniprot id: C4R3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC5 family.
messages: Cytoplasm
messages: May be involved in a process influencing telomere capping.

644223:PAS chr4 0429
gene id: 644223:PAS_chr4_0429
uniprot id: C4R7V5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr3 1037
gene id: 644223:PAS_chr3_1037
uniprot id: C4R6B4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

644223:PAS chr3 0582
gene id: 644223:PAS_chr3_0582
uniprot id: C4R4Z3
names: Similarity
messages: Belongs to the PHF5 family.

644223:PAS chr3 0569
gene id: 644223:PAS_chr3_0569
uniprot id: C4R4Y1
names: Similarity
messages: Belongs to the biotin--protein ligase family.

644223:PAS chr2-1 0176
gene id: 644223:PAS_chr2-1_0176
uniprot id: C4QZV9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

644223:PAS chr1-3 0268
gene id: 644223:PAS_chr1-3_0268
uniprot id: C4QVQ9
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

644223:PAS chr2-2 0302
gene id: 644223:PAS_chr2-2_0302
uniprot id: C4R281
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.

644223:PAS chr1-1 0100
gene id: 644223:PAS_chr1-1_0100
uniprot id: C4QW39
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

644223:PAS chr2-1 0127
gene id: 644223:PAS_chr2-1_0127
uniprot id: C4QZQ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

644223:PAS chr3 1136
gene id: 644223:PAS_chr3_1136
uniprot id: C4R370
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

644223:PAS chr4 0543
gene id: 644223:PAS_chr4_0543
uniprot id: C4R878
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

644223:PAS chr1-1 0277
gene id: 644223:PAS_chr1-1_0277
uniprot id: C4QWM6
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

644223:PAS chr2-1 0889
gene id: 644223:PAS_chr2-1_0889
uniprot id: C4R1R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

644223:PAS chr3 0570
gene id: 644223:PAS_chr3_0570
uniprot id: C4R4Y2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

644223:PAS chr1-3 0052
gene id: 644223:PAS_chr1-3_0052
uniprot id: C4QV32
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

644223:PAS chr2-1 0784
gene id: 644223:PAS_chr2-1_0784
uniprot id: C4R1R8
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-2 0346
gene id: 644223:PAS_chr2-2_0346
uniprot id: C4R236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

644223:PAS chr3 0283
gene id: 644223:PAS_chr3_0283
uniprot id: C4R437
names: Similarity
messages: Belongs to the amidase family.

644223:PAS chr2-1 0589
gene id: 644223:PAS_chr2-1_0589
uniprot id: C4R152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr1-1 0206
gene id: 644223:PAS_chr1-1_0206
uniprot id: C4QWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

644223:PAS chr2-1 0825
gene id: 644223:PAS_chr2-1_0825
uniprot id: C4R093
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

644223:PAS chr2-2 0453
gene id: 644223:PAS_chr2-2_0453
uniprot id: C4R309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

644223:PAS FragB 0041
gene id: 644223:PAS_FragB_0041
uniprot id: C4QZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

644223:PAS chr2-1 0572
gene id: 644223:PAS_chr2-1_0572
uniprot id: C4R134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Membrane

644223:PAS chr4 0251
gene id: 644223:PAS_chr4_0251
uniprot id: C4R7A7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

644223:PAS chr2-1 0247
gene id: 644223:PAS_chr2-1_0247
uniprot id: C4R035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

644223:PAS chr2-1 0637
gene id: 644223:PAS_chr2-1_0637
uniprot id: C4R1A7
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

644223:PAS chr2-1 0238
gene id: 644223:PAS_chr2-1_0238
uniprot id: C4R024
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

644223:PAS chr2-1 0401
gene id: 644223:PAS_chr2-1_0401
uniprot id: C4R0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

644223:PAS chr3 0058
gene id: 644223:PAS_chr3_0058
uniprot id: C4R3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

644223:PAS chr1-4 0078
gene id: 644223:PAS_chr1-4_0078
uniprot id: C4QXD4
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr1-4 0089
gene id: 644223:PAS_chr1-4_0089
uniprot id: C4QXE5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-4 0061
gene id: 644223:PAS_chr1-4_0061
uniprot id: C4QXB7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

644223:PAS chr1-1 0487
gene id: 644223:PAS_chr1-1_0487
uniprot id: C4QWK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

644223:PAS chr2-2 0348
gene id: 644223:PAS_chr2-2_0348
uniprot id: C4R233
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

644223:PAS chr3 0177
gene id: 644223:PAS_chr3_0177
uniprot id: C4R3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

644223:PAS chr4 0783
gene id: 644223:PAS_chr4_0783
uniprot id: C4R8X4
names: Similarity
messages: Belongs to the FGGY kinase family.

644223:PAS chr2-1 0245
gene id: 644223:PAS_chr2-1_0245
uniprot id: C4R033
names: Similarity
messages: Belongs to the SURF6 family.

644223:PAS chr2-2 0395
gene id: 644223:PAS_chr2-2_0395
uniprot id: C4R1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AEP1 family.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.

644223:PAS FragB 0063
gene id: 644223:PAS_FragB_0063
uniprot id: C4QZC0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

644223:PAS chr1-4 0584
gene id: 644223:PAS_chr1-4_0584
uniprot id: C4QYW7
names: Subcellular Location Annotation
messages: Cell surface

644223:PAS chr2-1 0813
gene id: 644223:PAS_chr2-1_0813
uniprot id: C4QZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

644223:PAS chr2-1 0356
gene id: 644223:PAS_chr2-1_0356
uniprot id: C4R0F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

644223:PAS chr2-1 0257
gene id: 644223:PAS_chr2-1_0257
uniprot id: C4R045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

644223:PAS chr2-1 0065
gene id: 644223:PAS_chr2-1_0065
uniprot id: C4QZJ2
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr4 0878
gene id: 644223:PAS_chr4_0878
uniprot id: C4R973
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr4 0387
gene id: 644223:PAS_chr4_0387
uniprot id: C4R7R0
names: Similarity
messages: Belongs to the AAA ATPase family.

644223:PAS chr4 0024
gene id: 644223:PAS_chr4_0024
uniprot id: C4R6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

644223:PAS chr1-4 0453
gene id: 644223:PAS_chr1-4_0453
uniprot id: C4QYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

644223:PAS chr2-1 0056
gene id: 644223:PAS_chr2-1_0056
uniprot id: C4QZI3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

644223:PAS chr4 0704
gene id: 644223:PAS_chr4_0704
uniprot id: C4R8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

644223:PAS chr4 0617
gene id: 644223:PAS_chr4_0617
uniprot id: C4R8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

644223:PAS chr2-1 0446
gene id: 644223:PAS_chr2-1_0446
uniprot id: C4R0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRI1 family.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr1-4 0503
gene id: 644223:PAS_chr1-4_0503
uniprot id: C4QYN3
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

644223:PAS chr3 0359
gene id: 644223:PAS_chr3_0359
uniprot id: C4R4B5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

644223:PAS chr4 0463
gene id: 644223:PAS_chr4_0463
uniprot id: C4R7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

644223:PAS chr4 0870
gene id: 644223:PAS_chr4_0870
uniprot id: C4R965
names: Similarity
messages: Belongs to the YIP1 family.

644223:PAS chr3 0427
gene id: 644223:PAS_chr3_0427
uniprot id: C4R4J1
names: Subcellular Location Annotation
messages: Membrane

644223:PAS chr2-1 0182
gene id: 644223:PAS_chr2-1_0182
uniprot id: C4QZW6
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

644223:PAS chr2-1 0471
gene id: 644223:PAS_chr2-1_0471
uniprot id: C4R0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

644223:PAS chr2-1 0391
gene id: 644223:PAS_chr2-1_0391
uniprot id: C4R0I8
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

644223:PAS chr2-1 0338
gene id: 644223:PAS_chr2-1_0338
uniprot id: C4R0D3
names: Similarity
messages: Belongs to the MTFP1 family.

644223:PAS chr4 0034
gene id: 644223:PAS_chr4_0034
uniprot id: C4R6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

644223:PAS chr3 0531
gene id: 644223:PAS_chr3_0531
uniprot id: C4R4U4
names: Similarity
messages: Belongs to the Rab GDI family.

644223:PAS chr4 0284
gene id: 644223:PAS_chr4_0284
uniprot id: C4R7E5
names: Similarity
messages: Belongs to the thioredoxin family.

644223:PAS chr4 0697
gene id: 644223:PAS_chr4_0697
uniprot id: C4R8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

644223:PAS chr4 0250
gene id: 644223:PAS_chr4_0250
uniprot id: C4R7A6
names: Similarity
messages: Belongs to the DEAD box helicase family.

644223:PAS chr1-1 0023
gene id: 644223:PAS_chr1-1_0023
uniprot id: C4QVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

644223:PAS chr2-2 0340
gene id: 644223:PAS_chr2-2_0340
uniprot id: C4R242
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr1-4 0171
gene id: 644223:PAS_chr1-4_0171
uniprot id: C4QXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

644223:PAS chr1-1 0449
gene id: 644223:PAS_chr1-1_0449
uniprot id: C4QX53
names: Similarity
messages: Belongs to the WrbA family.

644223:PAS chr2-1 0493
gene id: 644223:PAS_chr2-1_0493
uniprot id: C4R0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

644223:PAS chr2-1 0656
gene id: 644223:PAS_chr2-1_0656
uniprot id: C4R1C7
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

644223:PAS chr1-3 0209
gene id: 644223:PAS_chr1-3_0209
uniprot id: C4QVK0
names: Similarity
messages: Belongs to the syntaxin family.

644223:PAS chr1-1 0025
gene id: 644223:PAS_chr1-1_0025
uniprot id: C4QVV6
names: Similarity
messages: Belongs to the XPC family.

644223:PAS chr1-4 0153
gene id: 644223:PAS_chr1-4_0153
uniprot id: C4QXL0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

644223:PAS chr3 1185
gene id: 644223:PAS_chr3_1185
uniprot id: C4R4E6
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

644223:PAS chr3 0699
gene id: 644223:PAS_chr3_0699
uniprot id: C4R5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

644223:PAS chr2-1 0683
gene id: 644223:PAS_chr2-1_0683
uniprot id: C4R1F6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

644223:PAS chr3 0361
gene id: 644223:PAS_chr3_0361
uniprot id: C4R4B7
names: Similarity
messages: Belongs to the isochorismatase family.

644223:PAS chr1-4 0019
gene id: 644223:PAS_chr1-4_0019
uniprot id: C4QX80
names: Cofactor
names: Disruption Phenotype
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane
messages: Results in an almost complete loss of mitochondrial phosphatidylserine decarboxylase activity.

644223:PAS chr1-4 0492
gene id: 644223:PAS_chr1-4_0492
uniprot id: C4QYM2
names: Subcellular Location Annotation
messages: Nucleus

644223:PAS chr2-1 0838
gene id: 644223:PAS_chr2-1_0838
uniprot id: C4R0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

644223:PAS chr2-2 0391
gene id: 644223:PAS_chr2-2_0391
uniprot id: C4R1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

644223:PAS chr1-4 0098
gene id: 644223:PAS_chr1-4_0098
uniprot id: C4QXF5
names: Similarity
messages: Belongs to the KRI1 family.

644223:PAS chr3 0382
gene id: 644223:PAS_chr3_0382
uniprot id: C4R4E1
names: Similarity
messages: Belongs to the small Tim family.

644223:PAS chr4 0624
gene id: 644223:PAS_chr4_0624
uniprot id: C4R8F9
names: Similarity
messages: Belongs to the hexokinase family.

644223:PAS chr1-1 0195
gene id: 644223:PAS_chr1-1_0195
uniprot id: C4QWD8
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

644223:PAS chr1-3 0068
gene id: 644223:PAS_chr1-3_0068
uniprot id: C4QV50
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

644223:PAS chr1-1 0245
gene id: 644223:PAS_chr1-1_0245
uniprot id: C4QWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

644223:PAS chr1-3 0218
gene id: 644223:PAS_chr1-3_0218
uniprot id: C4QVK8
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

644223:PAS chr1-1 0024
gene id: 644223:PAS_chr1-1_0024
uniprot id: C4QVV5
names: Similarity
messages: Belongs to the SPT2 family.