643648:SLIP RS07240
gene id: 643648:SLIP_RS07240
uniprot id: D7CND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

643648:SLIP RS07100
gene id: 643648:SLIP_RS07100
uniprot id: D7CNB1
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

643648:SLIP RS10775
gene id: 643648:SLIP_RS10775
uniprot id: D7CJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

643648:SLIP RS08675
gene id: 643648:SLIP_RS08675
uniprot id: D7CP63
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

643648:SLIP RS04460
gene id: 643648:SLIP_RS04460
uniprot id: D7CLV0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

643648:SLIP RS02735
gene id: 643648:SLIP_RS02735
uniprot id: D7CKW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

643648:SLIP RS10190
gene id: 643648:SLIP_RS10190
uniprot id: D7CIS5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

643648:SLIP RS02420
gene id: 643648:SLIP_RS02420
uniprot id: D7CKP8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS00555
gene id: 643648:SLIP_RS00555
uniprot id: D7CIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

643648:SLIP RS03125
gene id: 643648:SLIP_RS03125
uniprot id: D7CL39
names: Similarity
messages: Belongs to the CapA family.

643648:SLIP RS11515
gene id: 643648:SLIP_RS11515
uniprot id: D7CK74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

643648:SLIP RS03490
gene id: 643648:SLIP_RS03490
uniprot id: D7CLA9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

643648:SLIP RS03910
gene id: 643648:SLIP_RS03910
uniprot id: D7CLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

643648:SLIP RS11140
gene id: 643648:SLIP_RS11140
uniprot id: D7CJN6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643648:SLIP RS05300
gene id: 643648:SLIP_RS05300
uniprot id: D7CMB6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

643648:SLIP RS07575
gene id: 643648:SLIP_RS07575
uniprot id: D7CNK7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643648:SLIP RS03095
gene id: 643648:SLIP_RS03095
uniprot id: D7CL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS03985
gene id: 643648:SLIP_RS03985
uniprot id: D7CLK3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643648:SLIP RS04005
gene id: 643648:SLIP_RS04005
uniprot id: D7CLK8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

643648:SLIP RS04680
gene id: 643648:SLIP_RS04680
uniprot id: D7CLZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

643648:SLIP RS08240
gene id: 643648:SLIP_RS08240
uniprot id: D7CNY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

643648:SLIP RS05750
gene id: 643648:SLIP_RS05750
uniprot id: D7CMK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11980
gene id: 643648:SLIP_RS11980
uniprot id: D7CLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

643648:SLIP RS05380
gene id: 643648:SLIP_RS05380
uniprot id: D7CMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

643648:SLIP RS08475
gene id: 643648:SLIP_RS08475
uniprot id: D7CP25
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS07015
gene id: 643648:SLIP_RS07015
uniprot id: D7CN94
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04450
gene id: 643648:SLIP_RS04450
uniprot id: D7CLU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

643648:SLIP RS02290
gene id: 643648:SLIP_RS02290
uniprot id: D7CKM1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

643648:SLIP RS10870
gene id: 643648:SLIP_RS10870
uniprot id: D7CJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS11345
gene id: 643648:SLIP_RS11345
uniprot id: D7CJS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

643648:SLIP RS01975
gene id: 643648:SLIP_RS01975
uniprot id: D7CKF6
names: Similarity
messages: Belongs to the peptidase U62 family.

643648:SLIP RS03775
gene id: 643648:SLIP_RS03775
uniprot id: D7CLG1
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04120
gene id: 643648:SLIP_RS04120
uniprot id: D7CLN1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

643648:SLIP RS02970
gene id: 643648:SLIP_RS02970
uniprot id: D7CL09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

643648:SLIP RS12000
gene id: 643648:SLIP_RS12000
uniprot id: D7CMA1
names: Similarity
messages: Belongs to the peptidase C40 family.

643648:SLIP RS05235
gene id: 643648:SLIP_RS05235
uniprot id: D7CMA4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

643648:SLIP RS08210
gene id: 643648:SLIP_RS08210
uniprot id: D7CNX7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

643648:SLIP RS10135
gene id: 643648:SLIP_RS10135
uniprot id: D7CIR5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

643648:SLIP RS05040
gene id: 643648:SLIP_RS05040
uniprot id: D7CM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS03340
gene id: 643648:SLIP_RS03340
uniprot id: D7CL81
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS01725
gene id: 643648:SLIP_RS01725
uniprot id: D7CK27
names: Similarity
messages: Belongs to the UPF0297 family.

643648:SLIP RS10715
gene id: 643648:SLIP_RS10715
uniprot id: D7CJ27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS07140
gene id: 643648:SLIP_RS07140
uniprot id: D7CNB8
names: Similarity
messages: Belongs to the UbiD family.

643648:SLIP RS02740
gene id: 643648:SLIP_RS02740
uniprot id: D7CKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

643648:SLIP RS00030
gene id: 643648:SLIP_RS00030
uniprot id: D7CPP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

643648:SLIP RS04145
gene id: 643648:SLIP_RS04145
uniprot id: D7CLN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

643648:SLIP RS08720
gene id: 643648:SLIP_RS08720
uniprot id: D7CP72
names: Similarity
messages: Belongs to the TrpC family.

643648:SLIP RS11325
gene id: 643648:SLIP_RS11325
uniprot id: D7CJR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

643648:SLIP RS07410
gene id: 643648:SLIP_RS07410
uniprot id: D7CNH3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

643648:SLIP RS05865
gene id: 643648:SLIP_RS05865
uniprot id: D7CMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

643648:SLIP RS11130
gene id: 643648:SLIP_RS11130
uniprot id: D7CJN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643648:SLIP RS11820
gene id: 643648:SLIP_RS11820
uniprot id: D7CKD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10900
gene id: 643648:SLIP_RS10900
uniprot id: D7CJI7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

643648:SLIP RS04115
gene id: 643648:SLIP_RS04115
uniprot id: D7CLN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

643648:SLIP RS11060
gene id: 643648:SLIP_RS11060
uniprot id: D7CJL9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

643648:SLIP RS02170
gene id: 643648:SLIP_RS02170
uniprot id: D7CKJ5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS11380
gene id: 643648:SLIP_RS11380
uniprot id: D7CJS8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

643648:SLIP RS01130
gene id: 643648:SLIP_RS01130
uniprot id: D7CJD2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

643648:SLIP RS02975
gene id: 643648:SLIP_RS02975
uniprot id: D7CL10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

643648:SLIP RS01655
gene id: 643648:SLIP_RS01655
uniprot id: D7CK11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

643648:SLIP RS02630
gene id: 643648:SLIP_RS02630
uniprot id: D7CKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

643648:SLIP RS00680
gene id: 643648:SLIP_RS00680
uniprot id: D7CJ43
names: Similarity
messages: Belongs to the DHPS family.

643648:SLIP RS10810
gene id: 643648:SLIP_RS10810
uniprot id: D7CJH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

643648:SLIP RS11395
gene id: 643648:SLIP_RS11395
uniprot id: D7CJT1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

643648:SLIP RS04055
gene id: 643648:SLIP_RS04055
uniprot id: D7CLL8
names: Subcellular Location Annotation
messages: Cytoplasm

643648:SLIP RS01180
gene id: 643648:SLIP_RS01180
uniprot id: D7CJE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

643648:SLIP RS03190
gene id: 643648:SLIP_RS03190
uniprot id: D7CL51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

643648:SLIP RS03055
gene id: 643648:SLIP_RS03055
uniprot id: D7CL25
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

643648:SLIP RS00015
gene id: 643648:SLIP_RS00015
uniprot id: D7CPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

643648:SLIP RS00040
gene id: 643648:SLIP_RS00040
uniprot id: D7CIF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

643648:SLIP RS10510
gene id: 643648:SLIP_RS10510
uniprot id: D7CIY8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

643648:SLIP RS00955
gene id: 643648:SLIP_RS00955
uniprot id: D7CJA0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

643648:SLIP RS01800
gene id: 643648:SLIP_RS01800
uniprot id: D7CK42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

643648:SLIP RS07820
gene id: 643648:SLIP_RS07820
uniprot id: D7CNQ0
names: Similarity
messages: Belongs to the asparagine synthetase family.

643648:SLIP RS11810
gene id: 643648:SLIP_RS11810
uniprot id: D7CKD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

643648:SLIP RS09540
gene id: 643648:SLIP_RS09540
uniprot id: D7CPP9
names: Similarity
messages: Belongs to the peptidase A24 family.

643648:SLIP RS03220
gene id: 643648:SLIP_RS03220
uniprot id: D7CL57
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

643648:SLIP RS03205
gene id: 643648:SLIP_RS03205
uniprot id: D7CL54
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04260
gene id: 643648:SLIP_RS04260
uniprot id: D7CLQ9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

643648:SLIP RS02465
gene id: 643648:SLIP_RS02465
uniprot id: D7CKQ6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

643648:SLIP RS02150
gene id: 643648:SLIP_RS02150
uniprot id: D7CKJ1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

643648:SLIP RS07420
gene id: 643648:SLIP_RS07420
uniprot id: D7CNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

643648:SLIP RS07915
gene id: 643648:SLIP_RS07915
uniprot id: D7CNS1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

643648:SLIP RS02530
gene id: 643648:SLIP_RS02530
uniprot id: D7CKR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

643648:SLIP RS00010
gene id: 643648:SLIP_RS00010
uniprot id: D7CPN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

643648:SLIP RS09345
gene id: 643648:SLIP_RS09345
uniprot id: D7CPK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

643648:SLIP RS04040
gene id: 643648:SLIP_RS04040
uniprot id: D7CLL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

643648:SLIP RS11425
gene id: 643648:SLIP_RS11425
uniprot id: D7CJT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS02825
gene id: 643648:SLIP_RS02825
uniprot id: D7CKX9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS03745
gene id: 643648:SLIP_RS03745
uniprot id: D7CLF5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

643648:SLIP RS05325
gene id: 643648:SLIP_RS05325
uniprot id: D7CMC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS09195
gene id: 643648:SLIP_RS09195
uniprot id: D7CPH2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

643648:SLIP RS11480
gene id: 643648:SLIP_RS11480
uniprot id: D7CK67
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS07880
gene id: 643648:SLIP_RS07880
uniprot id: D7CNR3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

643648:SLIP RS02265
gene id: 643648:SLIP_RS02265
uniprot id: D7CKL6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

643648:SLIP RS06330
gene id: 643648:SLIP_RS06330
uniprot id: D7CMW4
names: Similarity
messages: Belongs to the UPF0175 family.

643648:SLIP RS11265
gene id: 643648:SLIP_RS11265
uniprot id: D7CJQ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS04875
gene id: 643648:SLIP_RS04875
uniprot id: D7CM32
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS00740
gene id: 643648:SLIP_RS00740
uniprot id: D7CJ55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS04640
gene id: 643648:SLIP_RS04640
uniprot id: D7CLY5
names: Similarity
messages: Belongs to the UPF0047 family.

643648:SLIP RS09200
gene id: 643648:SLIP_RS09200
uniprot id: D7CPH3
names: Similarity
messages: Belongs to the sigma-54 factor family.

643648:SLIP RS10160
gene id: 643648:SLIP_RS10160
uniprot id: D7CIR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

643648:SLIP RS03475
gene id: 643648:SLIP_RS03475
uniprot id: D7CLA6
names: Similarity
messages: Belongs to the AOR/FOR family.

643648:SLIP RS07430
gene id: 643648:SLIP_RS07430
uniprot id: D7CNH7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

643648:SLIP RS01075
gene id: 643648:SLIP_RS01075
uniprot id: D7CJC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

643648:SLIP RS02255
gene id: 643648:SLIP_RS02255
uniprot id: D7CKL4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS07780
gene id: 643648:SLIP_RS07780
uniprot id: D7CNP2
names: Similarity
messages: Belongs to the glutamate synthase family.

643648:SLIP RS07950
gene id: 643648:SLIP_RS07950
uniprot id: D7CNS9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS02940
gene id: 643648:SLIP_RS02940
uniprot id: D7CL03
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

643648:SLIP RS00315
gene id: 643648:SLIP_RS00315
uniprot id: D7CIJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS07635
gene id: 643648:SLIP_RS07635
uniprot id: D7CNM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

643648:SLIP RS06000
gene id: 643648:SLIP_RS06000
uniprot id: D7CMP9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

643648:SLIP RS04525
gene id: 643648:SLIP_RS04525
uniprot id: D7CLW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

643648:SLIP RS11255
gene id: 643648:SLIP_RS11255
uniprot id: D7CJQ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

643648:SLIP RS06980
gene id: 643648:SLIP_RS06980
uniprot id: D7CN88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643648:SLIP RS09360
gene id: 643648:SLIP_RS09360
uniprot id: D7CPK6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS02920
gene id: 643648:SLIP_RS02920
uniprot id: D7CKZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

643648:SLIP RS07675
gene id: 643648:SLIP_RS07675
uniprot id: D7CNM8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

643648:SLIP RS00830
gene id: 643648:SLIP_RS00830
uniprot id: D7CJ74
names: Similarity
messages: Belongs to the polysaccharide synthase family.

643648:SLIP RS11105
gene id: 643648:SLIP_RS11105
uniprot id: D7CJM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

643648:SLIP RS00810
gene id: 643648:SLIP_RS00810
uniprot id: D7CJ70
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

643648:SLIP RS02210
gene id: 643648:SLIP_RS02210
uniprot id: D7CKK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS07005
gene id: 643648:SLIP_RS07005
uniprot id: D7CN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

643648:SLIP RS02075
gene id: 643648:SLIP_RS02075
uniprot id: D7CKH6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

643648:SLIP RS02425
gene id: 643648:SLIP_RS02425
uniprot id: D7CKP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

643648:SLIP RS09180
gene id: 643648:SLIP_RS09180
uniprot id: D7CPG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

643648:SLIP RS02085
gene id: 643648:SLIP_RS02085
uniprot id: D7CKH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS07885
gene id: 643648:SLIP_RS07885
uniprot id: D7CNR4
names: Similarity
messages: Belongs to the AOR/FOR family.

643648:SLIP RS11895
gene id: 643648:SLIP_RS11895
uniprot id: D7CJF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS00780
gene id: 643648:SLIP_RS00780
uniprot id: D7CJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

643648:SLIP RS04765
gene id: 643648:SLIP_RS04765
uniprot id: D7CM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

643648:SLIP RS05720
gene id: 643648:SLIP_RS05720
uniprot id: D7CMJ5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

643648:SLIP RS04965
gene id: 643648:SLIP_RS04965
uniprot id: D7CM50
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

643648:SLIP RS02390
gene id: 643648:SLIP_RS02390
uniprot id: D7CKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643648:SLIP RS07390
gene id: 643648:SLIP_RS07390
uniprot id: D7CNG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643648:SLIP RS10945
gene id: 643648:SLIP_RS10945
uniprot id: D7CJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

643648:SLIP RS04065
gene id: 643648:SLIP_RS04065
uniprot id: D7CLM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

643648:SLIP RS08725
gene id: 643648:SLIP_RS08725
uniprot id: D7CP73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS04225
gene id: 643648:SLIP_RS04225
uniprot id: D7CLQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

643648:SLIP RS02540
gene id: 643648:SLIP_RS02540
uniprot id: D7CKS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

643648:SLIP RS06670
gene id: 643648:SLIP_RS06670
uniprot id: D7CN26
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

643648:SLIP RS00500
gene id: 643648:SLIP_RS00500
uniprot id: D7CIN2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS01630
gene id: 643648:SLIP_RS01630
uniprot id: D7CK06
names: Similarity
messages: Belongs to the UPF0251 family.

643648:SLIP RS10700
gene id: 643648:SLIP_RS10700
uniprot id: D7CJ24
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11725
gene id: 643648:SLIP_RS11725
uniprot id: D7CKB3
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS05355
gene id: 643648:SLIP_RS05355
uniprot id: D7CMC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

643648:SLIP RS06695
gene id: 643648:SLIP_RS06695
uniprot id: D7CN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

643648:SLIP RS05695
gene id: 643648:SLIP_RS05695
uniprot id: D7CMJ0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

643648:SLIP RS11030
gene id: 643648:SLIP_RS11030
uniprot id: D7CJL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

643648:SLIP RS04720
gene id: 643648:SLIP_RS04720
uniprot id: D7CM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS01765
gene id: 643648:SLIP_RS01765
uniprot id: D7CK35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

643648:SLIP RS10970
gene id: 643648:SLIP_RS10970
uniprot id: D7CJK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

643648:SLIP RS03980
gene id: 643648:SLIP_RS03980
uniprot id: D7CLK2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643648:SLIP RS03960
gene id: 643648:SLIP_RS03960
uniprot id: D7CLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

643648:SLIP RS11295
gene id: 643648:SLIP_RS11295
uniprot id: D7CJR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS03405
gene id: 643648:SLIP_RS03405
uniprot id: D7CL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

643648:SLIP RS07035
gene id: 643648:SLIP_RS07035
uniprot id: D7CN98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS06395
gene id: 643648:SLIP_RS06395
uniprot id: D7CMX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

643648:SLIP RS05185
gene id: 643648:SLIP_RS05185
uniprot id: D7CM94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

643648:SLIP RS09655
gene id: 643648:SLIP_RS09655
uniprot id: D7CPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS03370
gene id: 643648:SLIP_RS03370
uniprot id: D7CL87
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

643648:SLIP RS10950
gene id: 643648:SLIP_RS10950
uniprot id: D7CJJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

643648:SLIP RS06040
gene id: 643648:SLIP_RS06040
uniprot id: D7CMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS11415
gene id: 643648:SLIP_RS11415
uniprot id: D7CJT5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

643648:SLIP RS05110
gene id: 643648:SLIP_RS05110
uniprot id: D7CM79
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643648:SLIP RS03010
gene id: 643648:SLIP_RS03010
uniprot id: D7CL17
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

643648:SLIP RS07155
gene id: 643648:SLIP_RS07155
uniprot id: D7CNC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

643648:SLIP RS04480
gene id: 643648:SLIP_RS04480
uniprot id: D7CLV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

643648:SLIP RS10910
gene id: 643648:SLIP_RS10910
uniprot id: D7CJI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10295
gene id: 643648:SLIP_RS10295
uniprot id: D7CIU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS00735
gene id: 643648:SLIP_RS00735
uniprot id: D7CJ54
names: Similarity
messages: Belongs to the peptidase S58 family.

643648:SLIP RS03400
gene id: 643648:SLIP_RS03400
uniprot id: D7CL92
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

643648:SLIP RS06005
gene id: 643648:SLIP_RS06005
uniprot id: D7CMQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS05170
gene id: 643648:SLIP_RS05170
uniprot id: D7CM91
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS09170
gene id: 643648:SLIP_RS09170
uniprot id: D7CPG7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

643648:SLIP RS01275
gene id: 643648:SLIP_RS01275
uniprot id: D7CJG1
names: Similarity
messages: Belongs to the CapA family.

643648:SLIP RS11115
gene id: 643648:SLIP_RS11115
uniprot id: D7CJN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643648:SLIP RS03510
gene id: 643648:SLIP_RS03510
uniprot id: D7CLB3
names: Similarity
messages: Belongs to the thioredoxin family.

643648:SLIP RS02100
gene id: 643648:SLIP_RS02100
uniprot id: D7CKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

643648:SLIP RS09060
gene id: 643648:SLIP_RS09060
uniprot id: D7CPE5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

643648:SLIP RS10765
gene id: 643648:SLIP_RS10765
uniprot id: D7CJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

643648:SLIP RS10680
gene id: 643648:SLIP_RS10680
uniprot id: D7CJ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS05365
gene id: 643648:SLIP_RS05365
uniprot id: D7CMC9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

643648:SLIP RS03710
gene id: 643648:SLIP_RS03710
uniprot id: D7CLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

643648:SLIP RS05030
gene id: 643648:SLIP_RS05030
uniprot id: D7CM63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

643648:SLIP RS02430
gene id: 643648:SLIP_RS02430
uniprot id: D7CKQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS00640
gene id: 643648:SLIP_RS00640
uniprot id: D7CIQ9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

643648:SLIP RS01325
gene id: 643648:SLIP_RS01325
uniprot id: D7CJU6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

643648:SLIP RS11070
gene id: 643648:SLIP_RS11070
uniprot id: D7CJM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

643648:SLIP RS07665
gene id: 643648:SLIP_RS07665
uniprot id: D7CNM6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

643648:SLIP RS04465
gene id: 643648:SLIP_RS04465
uniprot id: D7CLV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

643648:SLIP RS01190
gene id: 643648:SLIP_RS01190
uniprot id: D7CJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS07115
gene id: 643648:SLIP_RS07115
uniprot id: D7CNB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

643648:SLIP RS00335
gene id: 643648:SLIP_RS00335
uniprot id: D7CIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

643648:SLIP RS02220
gene id: 643648:SLIP_RS02220
uniprot id: D7CKK6
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

643648:SLIP RS02810
gene id: 643648:SLIP_RS02810
uniprot id: D7CKX6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS03120
gene id: 643648:SLIP_RS03120
uniprot id: D7CL38
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

643648:SLIP RS04505
gene id: 643648:SLIP_RS04505
uniprot id: D7CLV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

643648:SLIP RS11015
gene id: 643648:SLIP_RS11015
uniprot id: D7CJL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

643648:SLIP RS01940
gene id: 643648:SLIP_RS01940
uniprot id: D7CKE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11655
gene id: 643648:SLIP_RS11655
uniprot id: D7CKA0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11410
gene id: 643648:SLIP_RS11410
uniprot id: D7CJT4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

643648:SLIP RS07710
gene id: 643648:SLIP_RS07710
uniprot id: D7CNN0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

643648:SLIP RS06370
gene id: 643648:SLIP_RS06370
uniprot id: D7CMX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

643648:SLIP RS09470
gene id: 643648:SLIP_RS09470
uniprot id: D7CPM8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

643648:SLIP RS03915
gene id: 643648:SLIP_RS03915
uniprot id: D7CLI9
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS07055
gene id: 643648:SLIP_RS07055
uniprot id: D7CNA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

643648:SLIP RS07010
gene id: 643648:SLIP_RS07010
uniprot id: D7CN93
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

643648:SLIP RS04885
gene id: 643648:SLIP_RS04885
uniprot id: D7CM34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

643648:SLIP RS08095
gene id: 643648:SLIP_RS08095
uniprot id: D7CNV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643648:SLIP RS04580
gene id: 643648:SLIP_RS04580
uniprot id: D7CLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

643648:SLIP RS10720
gene id: 643648:SLIP_RS10720
uniprot id: D7CJ28
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

643648:SLIP RS11135
gene id: 643648:SLIP_RS11135
uniprot id: D7CJN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

643648:SLIP RS09690
gene id: 643648:SLIP_RS09690
uniprot id: D7CPT1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643648:SLIP RS10185
gene id: 643648:SLIP_RS10185
uniprot id: D7CIS4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

643648:SLIP RS05120
gene id: 643648:SLIP_RS05120
uniprot id: D7CM81
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

643648:SLIP RS11795
gene id: 643648:SLIP_RS11795
uniprot id: D7CKC7
names: Similarity
messages: Belongs to the ParB family.

643648:SLIP RS03815
gene id: 643648:SLIP_RS03815
uniprot id: D7CLG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS00050
gene id: 643648:SLIP_RS00050
uniprot id: D7CIF3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

643648:SLIP RS09715
gene id: 643648:SLIP_RS09715
uniprot id: D7CPT5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

643648:SLIP RS02115
gene id: 643648:SLIP_RS02115
uniprot id: D7CKI4
names: Similarity
messages: Belongs to the TlyA family.

643648:SLIP RS11580
gene id: 643648:SLIP_RS11580
uniprot id: D7CK87
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

643648:SLIP RS07065
gene id: 643648:SLIP_RS07065
uniprot id: D7CNA4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

643648:SLIP RS06390
gene id: 643648:SLIP_RS06390
uniprot id: D7CMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

643648:SLIP RS01815
gene id: 643648:SLIP_RS01815
uniprot id: D7CK45
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS02755
gene id: 643648:SLIP_RS02755
uniprot id: D7CKW5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

643648:SLIP RS04280
gene id: 643648:SLIP_RS04280
uniprot id: D7CLR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

643648:SLIP RS11005
gene id: 643648:SLIP_RS11005
uniprot id: D7CJK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

643648:SLIP RS04010
gene id: 643648:SLIP_RS04010
uniprot id: D7CLK9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

643648:SLIP RS09450
gene id: 643648:SLIP_RS09450
uniprot id: D7CPM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

643648:SLIP RS06085
gene id: 643648:SLIP_RS06085
uniprot id: D7CMR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

643648:SLIP RS07020
gene id: 643648:SLIP_RS07020
uniprot id: D7CN95
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

643648:SLIP RS01865
gene id: 643648:SLIP_RS01865
uniprot id: D7CK55
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

643648:SLIP RS10675
gene id: 643648:SLIP_RS10675
uniprot id: D7CJ19
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

643648:SLIP RS03265
gene id: 643648:SLIP_RS03265
uniprot id: D7CL66
names: Similarity
messages: Belongs to the leucine-binding protein family.

643648:SLIP RS01510
gene id: 643648:SLIP_RS01510
uniprot id: D7CJY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

643648:SLIP RS05805
gene id: 643648:SLIP_RS05805
uniprot id: D7CML1
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04275
gene id: 643648:SLIP_RS04275
uniprot id: D7CLR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

643648:SLIP RS07230
gene id: 643648:SLIP_RS07230
uniprot id: D7CND5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

643648:SLIP RS10290
gene id: 643648:SLIP_RS10290
uniprot id: D7CIU6
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

643648:SLIP RS09175
gene id: 643648:SLIP_RS09175
uniprot id: D7CPG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

643648:SLIP RS06030
gene id: 643648:SLIP_RS06030
uniprot id: D7CMQ5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS00035
gene id: 643648:SLIP_RS00035
uniprot id: D7CPP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

643648:SLIP RS03595
gene id: 643648:SLIP_RS03595
uniprot id: D7CLC5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS11500
gene id: 643648:SLIP_RS11500
uniprot id: D7CK71
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS01260
gene id: 643648:SLIP_RS01260
uniprot id: D7CJF8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

643648:SLIP RS11805
gene id: 643648:SLIP_RS11805
uniprot id: D7CKC9
names: Similarity
messages: Belongs to the ParB family.

643648:SLIP RS00815
gene id: 643648:SLIP_RS00815
uniprot id: D7CJ71
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04035
gene id: 643648:SLIP_RS04035
uniprot id: D7CLL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

643648:SLIP RS06020
gene id: 643648:SLIP_RS06020
uniprot id: D7CMQ3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

643648:SLIP RS04445
gene id: 643648:SLIP_RS04445
uniprot id: D7CLU7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

643648:SLIP RS07350
gene id: 643648:SLIP_RS07350
uniprot id: D7CNG0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

643648:SLIP RS10755
gene id: 643648:SLIP_RS10755
uniprot id: D7CJ36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

643648:SLIP RS01595
gene id: 643648:SLIP_RS01595
uniprot id: D7CJZ9
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS10995
gene id: 643648:SLIP_RS10995
uniprot id: D7CJK6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

643648:SLIP RS05415
gene id: 643648:SLIP_RS05415
uniprot id: D7CMD8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

643648:SLIP RS04565
gene id: 643648:SLIP_RS04565
uniprot id: D7CLX0
names: Similarity
messages: Belongs to the CobH/CbiC family.

643648:SLIP RS05330
gene id: 643648:SLIP_RS05330
uniprot id: D7CMC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

643648:SLIP RS00840
gene id: 643648:SLIP_RS00840
uniprot id: D7CJ76
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

643648:SLIP RS02995
gene id: 643648:SLIP_RS02995
uniprot id: D7CL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

643648:SLIP RS08300
gene id: 643648:SLIP_RS08300
uniprot id: D7CNZ4
names: Similarity
messages: Belongs to the CdaR family.

643648:SLIP RS04345
gene id: 643648:SLIP_RS04345
uniprot id: D7CLS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS04500
gene id: 643648:SLIP_RS04500
uniprot id: D7CLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

643648:SLIP RS06890
gene id: 643648:SLIP_RS06890
uniprot id: D7CN71
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

643648:SLIP RS07370
gene id: 643648:SLIP_RS07370
uniprot id: D7CNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

643648:SLIP RS04325
gene id: 643648:SLIP_RS04325
uniprot id: D7CLS2
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

643648:SLIP RS04295
gene id: 643648:SLIP_RS04295
uniprot id: D7CLR6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

643648:SLIP RS08130
gene id: 643648:SLIP_RS08130
uniprot id: D7CNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

643648:SLIP RS09730
gene id: 643648:SLIP_RS09730
uniprot id: D7CPT8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643648:SLIP RS03445
gene id: 643648:SLIP_RS03445
uniprot id: D7CLA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

643648:SLIP RS04435
gene id: 643648:SLIP_RS04435
uniprot id: D7CLU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS01860
gene id: 643648:SLIP_RS01860
uniprot id: D7CK54
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

643648:SLIP RS10155
gene id: 643648:SLIP_RS10155
uniprot id: D7CIR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

643648:SLIP RS03955
gene id: 643648:SLIP_RS03955
uniprot id: D7CLJ7
names: Similarity
messages: Belongs to the UPF0749 family.

643648:SLIP RS06790
gene id: 643648:SLIP_RS06790
uniprot id: D7CN51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

643648:SLIP RS02520
gene id: 643648:SLIP_RS02520
uniprot id: D7CKR7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

643648:SLIP RS10940
gene id: 643648:SLIP_RS10940
uniprot id: D7CJJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

643648:SLIP RS09255
gene id: 643648:SLIP_RS09255
uniprot id: D7CPI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

643648:SLIP RS07365
gene id: 643648:SLIP_RS07365
uniprot id: D7CNG3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

643648:SLIP RS04665
gene id: 643648:SLIP_RS04665
uniprot id: D7CLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643648:SLIP RS00710
gene id: 643648:SLIP_RS00710
uniprot id: D7CJ49
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

643648:SLIP RS06520
gene id: 643648:SLIP_RS06520
uniprot id: D7CMZ7
names: Similarity
messages: Belongs to the Lgt family.

643648:SLIP RS00560
gene id: 643648:SLIP_RS00560
uniprot id: D7CIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

643648:SLIP RS00190
gene id: 643648:SLIP_RS00190
uniprot id: D7CIH4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

643648:SLIP RS10545
gene id: 643648:SLIP_RS10545
uniprot id: D7CIZ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

643648:SLIP RS00715
gene id: 643648:SLIP_RS00715
uniprot id: D7CJ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

643648:SLIP RS02550
gene id: 643648:SLIP_RS02550
uniprot id: D7CKS3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

643648:SLIP RS01935
gene id: 643648:SLIP_RS01935
uniprot id: D7CKE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS06660
gene id: 643648:SLIP_RS06660
uniprot id: D7CN24
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

643648:SLIP RS05085
gene id: 643648:SLIP_RS05085
uniprot id: D7CM74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS10780
gene id: 643648:SLIP_RS10780
uniprot id: D7CJG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

643648:SLIP RS04230
gene id: 643648:SLIP_RS04230
uniprot id: D7CLQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

643648:SLIP RS04770
gene id: 643648:SLIP_RS04770
uniprot id: D7CM11
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS00835
gene id: 643648:SLIP_RS00835
uniprot id: D7CJ75
names: Similarity
messages: Belongs to the archaeal-type GPI family.

643648:SLIP RS05765
gene id: 643648:SLIP_RS05765
uniprot id: D7CMK4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

643648:SLIP RS01930
gene id: 643648:SLIP_RS01930
uniprot id: D7CKE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

643648:SLIP RS03660
gene id: 643648:SLIP_RS03660
uniprot id: D7CLD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

643648:SLIP RS06530
gene id: 643648:SLIP_RS06530
uniprot id: D7CMZ9
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS07270
gene id: 643648:SLIP_RS07270
uniprot id: D7CNE3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

643648:SLIP RS11225
gene id: 643648:SLIP_RS11225
uniprot id: D7CJP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS02235
gene id: 643648:SLIP_RS02235
uniprot id: D7CKK9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

643648:SLIP RS09520
gene id: 643648:SLIP_RS09520
uniprot id: D7CPP5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS04905
gene id: 643648:SLIP_RS04905
uniprot id: D7CM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

643648:SLIP RS04895
gene id: 643648:SLIP_RS04895
uniprot id: D7CM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643648:SLIP RS05240
gene id: 643648:SLIP_RS05240
uniprot id: D7CMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

643648:SLIP RS03890
gene id: 643648:SLIP_RS03890
uniprot id: D7CLI4
names: Similarity
messages: Belongs to the transpeptidase family.

643648:SLIP RS10310
gene id: 643648:SLIP_RS10310
uniprot id: D7CIV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS11065
gene id: 643648:SLIP_RS11065
uniprot id: D7CJM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

643648:SLIP RS09205
gene id: 643648:SLIP_RS09205
uniprot id: D7CPH4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

643648:SLIP RS04215
gene id: 643648:SLIP_RS04215
uniprot id: D7CLQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643648:SLIP RS01110
gene id: 643648:SLIP_RS01110
uniprot id: D7CJC8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643648:SLIP RS00485
gene id: 643648:SLIP_RS00485
uniprot id: D7CIM9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643648:SLIP RS04735
gene id: 643648:SLIP_RS04735
uniprot id: D7CM04
names: Similarity
messages: Belongs to the FlgD family.

643648:SLIP RS04695
gene id: 643648:SLIP_RS04695
uniprot id: D7CLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

643648:SLIP RS08485
gene id: 643648:SLIP_RS08485
uniprot id: D7CP27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

643648:SLIP RS03395
gene id: 643648:SLIP_RS03395
uniprot id: D7CL91
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

643648:SLIP RS09845
gene id: 643648:SLIP_RS09845
uniprot id: D7CPV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS11470
gene id: 643648:SLIP_RS11470
uniprot id: D7CK65
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

643648:SLIP RS02785
gene id: 643648:SLIP_RS02785
uniprot id: D7CKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

643648:SLIP RS04240
gene id: 643648:SLIP_RS04240
uniprot id: D7CLQ5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

643648:SLIP RS06855
gene id: 643648:SLIP_RS06855
uniprot id: D7CN64
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

643648:SLIP RS08220
gene id: 643648:SLIP_RS08220
uniprot id: D7CNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

643648:SLIP RS10485
gene id: 643648:SLIP_RS10485
uniprot id: D7CIY3
names: Similarity
messages: Belongs to the P(II) protein family.

643648:SLIP RS06840
gene id: 643648:SLIP_RS06840
uniprot id: D7CN61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

643648:SLIP RS11000
gene id: 643648:SLIP_RS11000
uniprot id: D7CJK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

643648:SLIP RS07435
gene id: 643648:SLIP_RS07435
uniprot id: D7CNH8
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS00660
gene id: 643648:SLIP_RS00660
uniprot id: D7CIR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10575
gene id: 643648:SLIP_RS10575
uniprot id: D7CJ01
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

643648:SLIP RS02330
gene id: 643648:SLIP_RS02330
uniprot id: D7CKN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS07855
gene id: 643648:SLIP_RS07855
uniprot id: D7CNQ8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

643648:SLIP RS11020
gene id: 643648:SLIP_RS11020
uniprot id: D7CJL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

643648:SLIP RS11485
gene id: 643648:SLIP_RS11485
uniprot id: D7CK68
names: Similarity
messages: Belongs to the peptidase S49 family.

643648:SLIP RS01270
gene id: 643648:SLIP_RS01270
uniprot id: D7CJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643648:SLIP RS03005
gene id: 643648:SLIP_RS03005
uniprot id: D7CL16
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

643648:SLIP RS05970
gene id: 643648:SLIP_RS05970
uniprot id: D7CMP3
names: Similarity
messages: Belongs to the histone deacetylase family.

643648:SLIP RS05510
gene id: 643648:SLIP_RS05510
uniprot id: D7CMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

643648:SLIP RS11460
gene id: 643648:SLIP_RS11460
uniprot id: D7CK63
names: Similarity
messages: Belongs to the FBPase class 2 family.

643648:SLIP RS05770
gene id: 643648:SLIP_RS05770
uniprot id: D7CMK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

643648:SLIP RS12585
gene id: 643648:SLIP_RS12585
uniprot id: D7CN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS04980
gene id: 643648:SLIP_RS04980
uniprot id: D7CM53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

643648:SLIP RS04585
gene id: 643648:SLIP_RS04585
uniprot id: D7CLX4
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04030
gene id: 643648:SLIP_RS04030
uniprot id: D7CLL3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

643648:SLIP RS04385
gene id: 643648:SLIP_RS04385
uniprot id: D7CLT4
names: Similarity
messages: Belongs to the asp23 family.

643648:SLIP RS05915
gene id: 643648:SLIP_RS05915
uniprot id: D7CMN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS01870
gene id: 643648:SLIP_RS01870
uniprot id: D7CK56
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

643648:SLIP RS10570
gene id: 643648:SLIP_RS10570
uniprot id: D7CJ00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS04365
gene id: 643648:SLIP_RS04365
uniprot id: D7CLT0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS08845
gene id: 643648:SLIP_RS08845
uniprot id: D7CP95
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

643648:SLIP RS08275
gene id: 643648:SLIP_RS08275
uniprot id: D7CNZ0
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS03650
gene id: 643648:SLIP_RS03650
uniprot id: D7CLD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

643648:SLIP RS11975
gene id: 643648:SLIP_RS11975
uniprot id: D7CLG2
names: Similarity
messages: Belongs to the RecJ family.

643648:SLIP RS05125
gene id: 643648:SLIP_RS05125
uniprot id: D7CM82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

643648:SLIP RS12105
gene id: 643648:SLIP_RS12105
uniprot id: D7CNI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

643648:SLIP RS09480
gene id: 643648:SLIP_RS09480
uniprot id: D7CPN0
names: Similarity
messages: Belongs to the FlgM family.

643648:SLIP RS04140
gene id: 643648:SLIP_RS04140
uniprot id: D7CLN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

643648:SLIP RS02660
gene id: 643648:SLIP_RS02660
uniprot id: D7CKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

643648:SLIP RS05000
gene id: 643648:SLIP_RS05000
uniprot id: D7CM57
names: Similarity
messages: Belongs to the peptidase M16 family.

643648:SLIP RS10540
gene id: 643648:SLIP_RS10540
uniprot id: D7CIZ4
names: Similarity
messages: Belongs to the P(II) protein family.

643648:SLIP RS04590
gene id: 643648:SLIP_RS04590
uniprot id: D7CLX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

643648:SLIP RS00005
gene id: 643648:SLIP_RS00005
uniprot id: D7CPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

643648:SLIP RS08340
gene id: 643648:SLIP_RS08340
uniprot id: D7CP00
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS09245
gene id: 643648:SLIP_RS09245
uniprot id: D7CPI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

643648:SLIP RS11075
gene id: 643648:SLIP_RS11075
uniprot id: D7CJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS11200
gene id: 643648:SLIP_RS11200
uniprot id: D7CJP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS03270
gene id: 643648:SLIP_RS03270
uniprot id: D7CL67
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS01470
gene id: 643648:SLIP_RS01470
uniprot id: D7CJX5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS08710
gene id: 643648:SLIP_RS08710
uniprot id: D7CP70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

643648:SLIP RS11690
gene id: 643648:SLIP_RS11690
uniprot id: D7CKA6
names: Similarity
messages: Belongs to the peptidase M18 family.

643648:SLIP RS05645
gene id: 643648:SLIP_RS05645
uniprot id: D7CMI4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS03335
gene id: 643648:SLIP_RS03335
uniprot id: D7CL80
names: Similarity
messages: Belongs to the UPF0111 family.

643648:SLIP RS04475
gene id: 643648:SLIP_RS04475
uniprot id: D7CLV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

643648:SLIP RS04795
gene id: 643648:SLIP_RS04795
uniprot id: D7CM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

643648:SLIP RS10975
gene id: 643648:SLIP_RS10975
uniprot id: D7CJK2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

643648:SLIP RS00195
gene id: 643648:SLIP_RS00195
uniprot id: D7CIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

643648:SLIP RS11330
gene id: 643648:SLIP_RS11330
uniprot id: D7CJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

643648:SLIP RS04595
gene id: 643648:SLIP_RS04595
uniprot id: D7CLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

643648:SLIP RS01420
gene id: 643648:SLIP_RS01420
uniprot id: D7CJW5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

643648:SLIP RS08120
gene id: 643648:SLIP_RS08120
uniprot id: D7CNV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

643648:SLIP RS06835
gene id: 643648:SLIP_RS06835
uniprot id: D7CN60
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

643648:SLIP RS11750
gene id: 643648:SLIP_RS11750
uniprot id: D7CKB8
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

643648:SLIP RS01905
gene id: 643648:SLIP_RS01905
uniprot id: D7CKE2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643648:SLIP RS03945
gene id: 643648:SLIP_RS03945
uniprot id: D7CLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643648:SLIP RS10990
gene id: 643648:SLIP_RS10990
uniprot id: D7CJK5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS03615
gene id: 643648:SLIP_RS03615
uniprot id: D7CLC9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

643648:SLIP RS02760
gene id: 643648:SLIP_RS02760
uniprot id: D7CKW6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

643648:SLIP RS06775
gene id: 643648:SLIP_RS06775
uniprot id: D7CN48
names: Similarity
messages: Belongs to the peptidase S16 family.

643648:SLIP RS10530
gene id: 643648:SLIP_RS10530
uniprot id: D7CIZ2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

643648:SLIP RS04045
gene id: 643648:SLIP_RS04045
uniprot id: D7CLL6
names: Similarity
messages: Belongs to the YggT family.

643648:SLIP RS10590
gene id: 643648:SLIP_RS10590
uniprot id: D7CJ04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

643648:SLIP RS02455
gene id: 643648:SLIP_RS02455
uniprot id: D7CKQ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

643648:SLIP RS05335
gene id: 643648:SLIP_RS05335
uniprot id: D7CMC3
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

643648:SLIP RS10520
gene id: 643648:SLIP_RS10520
uniprot id: D7CIZ0
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

643648:SLIP RS01350
gene id: 643648:SLIP_RS01350
uniprot id: D7CJV2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

643648:SLIP RS04700
gene id: 643648:SLIP_RS04700
uniprot id: D7CLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

643648:SLIP RS09565
gene id: 643648:SLIP_RS09565
uniprot id: D7CPQ3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643648:SLIP RS00705
gene id: 643648:SLIP_RS00705
uniprot id: D7CJ48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

643648:SLIP RS05990
gene id: 643648:SLIP_RS05990
uniprot id: D7CMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS04785
gene id: 643648:SLIP_RS04785
uniprot id: D7CM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

643648:SLIP RS00055
gene id: 643648:SLIP_RS00055
uniprot id: D7CIF4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS06610
gene id: 643648:SLIP_RS06610
uniprot id: D7CN15
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS05310
gene id: 643648:SLIP_RS05310
uniprot id: D7CMB8
names: Similarity
messages: Belongs to the histone deacetylase family.

643648:SLIP RS00730
gene id: 643648:SLIP_RS00730
uniprot id: D7CJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

643648:SLIP RS00205
gene id: 643648:SLIP_RS00205
uniprot id: D7CIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

643648:SLIP RS09130
gene id: 643648:SLIP_RS09130
uniprot id: D7CPF9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

643648:SLIP RS08200
gene id: 643648:SLIP_RS08200
uniprot id: D7CNX5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

643648:SLIP RS08190
gene id: 643648:SLIP_RS08190
uniprot id: D7CNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

643648:SLIP RS11640
gene id: 643648:SLIP_RS11640
uniprot id: D7CK98
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

643648:SLIP RS03455
gene id: 643648:SLIP_RS03455
uniprot id: D7CLA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

643648:SLIP RS10820
gene id: 643648:SLIP_RS10820
uniprot id: D7CJH2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

643648:SLIP RS01705
gene id: 643648:SLIP_RS01705
uniprot id: D7CK22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS05315
gene id: 643648:SLIP_RS05315
uniprot id: D7CMB9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

643648:SLIP RS05985
gene id: 643648:SLIP_RS05985
uniprot id: D7CMP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

643648:SLIP RS04135
gene id: 643648:SLIP_RS04135
uniprot id: D7CLN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10685
gene id: 643648:SLIP_RS10685
uniprot id: D7CJ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643648:SLIP RS01985
gene id: 643648:SLIP_RS01985
uniprot id: D7CKF8
names: Similarity
messages: Belongs to the peptidase M24B family.

643648:SLIP RS03655
gene id: 643648:SLIP_RS03655
uniprot id: D7CLD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

643648:SLIP RS09335
gene id: 643648:SLIP_RS09335
uniprot id: D7CPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

643648:SLIP RS02715
gene id: 643648:SLIP_RS02715
uniprot id: D7CKV6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

643648:SLIP RS10040
gene id: 643648:SLIP_RS10040
uniprot id: D7CPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

643648:SLIP RS08670
gene id: 643648:SLIP_RS08670
uniprot id: D7CP62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS04890
gene id: 643648:SLIP_RS04890
uniprot id: D7CM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

643648:SLIP RS03355
gene id: 643648:SLIP_RS03355
uniprot id: D7CL84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

643648:SLIP RS04440
gene id: 643648:SLIP_RS04440
uniprot id: D7CLU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11510
gene id: 643648:SLIP_RS11510
uniprot id: D7CK73
names: Similarity
messages: Belongs to the RpoE family.

643648:SLIP RS04955
gene id: 643648:SLIP_RS04955
uniprot id: D7CM48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

643648:SLIP RS11025
gene id: 643648:SLIP_RS11025
uniprot id: D7CJL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS01890
gene id: 643648:SLIP_RS01890
uniprot id: D7CKD9
names: Similarity
messages: Belongs to the HupF/HypC family.

643648:SLIP RS00720
gene id: 643648:SLIP_RS00720
uniprot id: D7CJ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

643648:SLIP RS02830
gene id: 643648:SLIP_RS02830
uniprot id: D7CKY0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS10785
gene id: 643648:SLIP_RS10785
uniprot id: D7CJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

643648:SLIP RS10840
gene id: 643648:SLIP_RS10840
uniprot id: D7CJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS04935
gene id: 643648:SLIP_RS04935
uniprot id: D7CM44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

643648:SLIP RS02095
gene id: 643648:SLIP_RS02095
uniprot id: D7CKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

643648:SLIP RS08290
gene id: 643648:SLIP_RS08290
uniprot id: D7CNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

643648:SLIP RS09630
gene id: 643648:SLIP_RS09630
uniprot id: D7CPR9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

643648:SLIP RS10885
gene id: 643648:SLIP_RS10885
uniprot id: D7CJI5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

643648:SLIP RS01015
gene id: 643648:SLIP_RS01015
uniprot id: D7CJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

643648:SLIP RS03345
gene id: 643648:SLIP_RS03345
uniprot id: D7CL82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

643648:SLIP RS04160
gene id: 643648:SLIP_RS04160
uniprot id: D7CLN9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

643648:SLIP RS01770
gene id: 643648:SLIP_RS01770
uniprot id: D7CK36
names: Similarity
messages: Belongs to the transpeptidase family.

643648:SLIP RS01970
gene id: 643648:SLIP_RS01970
uniprot id: D7CKF5
names: Similarity
messages: Belongs to the peptidase U62 family.

643648:SLIP RS03410
gene id: 643648:SLIP_RS03410
uniprot id: D7CL94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

643648:SLIP RS06825
gene id: 643648:SLIP_RS06825
uniprot id: D7CN58
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

643648:SLIP RS00765
gene id: 643648:SLIP_RS00765
uniprot id: D7CJ60
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

643648:SLIP RS01775
gene id: 643648:SLIP_RS01775
uniprot id: D7CK37
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS11620
gene id: 643648:SLIP_RS11620
uniprot id: D7CK94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS04755
gene id: 643648:SLIP_RS04755
uniprot id: D7CM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

643648:SLIP RS07075
gene id: 643648:SLIP_RS07075
uniprot id: D7CNA6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

643648:SLIP RS07130
gene id: 643648:SLIP_RS07130
uniprot id: D7CNB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS01810
gene id: 643648:SLIP_RS01810
uniprot id: D7CK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

643648:SLIP RS08430
gene id: 643648:SLIP_RS08430
uniprot id: D7CP17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

643648:SLIP RS07170
gene id: 643648:SLIP_RS07170
uniprot id: D7CNC4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

643648:SLIP RS01915
gene id: 643648:SLIP_RS01915
uniprot id: D7CKE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11955
gene id: 643648:SLIP_RS11955
uniprot id: D7CL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

643648:SLIP RS11730
gene id: 643648:SLIP_RS11730
uniprot id: D7CKB4
names: Similarity
messages: Belongs to the leucine-binding protein family.

643648:SLIP RS08805
gene id: 643648:SLIP_RS08805
uniprot id: D7CP87
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

643648:SLIP RS02560
gene id: 643648:SLIP_RS02560
uniprot id: D7CKS5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

643648:SLIP RS09280
gene id: 643648:SLIP_RS09280
uniprot id: D7CPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

643648:SLIP RS02610
gene id: 643648:SLIP_RS02610
uniprot id: D7CKT5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

643648:SLIP RS00210
gene id: 643648:SLIP_RS00210
uniprot id: D7CIH8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

643648:SLIP RS01900
gene id: 643648:SLIP_RS01900
uniprot id: D7CKE1
names: Similarity
messages: Belongs to the HypE family.

643648:SLIP RS01340
gene id: 643648:SLIP_RS01340
uniprot id: D7CJV0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

643648:SLIP RS10445
gene id: 643648:SLIP_RS10445
uniprot id: D7CIX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS07850
gene id: 643648:SLIP_RS07850
uniprot id: D7CNQ7
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS09445
gene id: 643648:SLIP_RS09445
uniprot id: D7CPM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

643648:SLIP RS10405
gene id: 643648:SLIP_RS10405
uniprot id: D7CIW9
names: Similarity
messages: Belongs to the AOR/FOR family.

643648:SLIP RS02185
gene id: 643648:SLIP_RS02185
uniprot id: D7CKJ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

643648:SLIP RS10025
gene id: 643648:SLIP_RS10025
uniprot id: D7CPZ0
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

643648:SLIP RS03665
gene id: 643648:SLIP_RS03665
uniprot id: D7CLD9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

643648:SLIP RS01790
gene id: 643648:SLIP_RS01790
uniprot id: D7CK40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643648:SLIP RS01530
gene id: 643648:SLIP_RS01530
uniprot id: D7CJY5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

643648:SLIP RS06915
gene id: 643648:SLIP_RS06915
uniprot id: D7CN76
names: Similarity
messages: Belongs to the Nudix hydrolase family.

643648:SLIP RS03865
gene id: 643648:SLIP_RS03865
uniprot id: D7CLH9
names: Similarity
messages: Belongs to the TrpF family.

643648:SLIP RS05255
gene id: 643648:SLIP_RS05255
uniprot id: D7CMA8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

643648:SLIP RS09740
gene id: 643648:SLIP_RS09740
uniprot id: D7CPU0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

643648:SLIP RS09960
gene id: 643648:SLIP_RS09960
uniprot id: D7CPX7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

643648:SLIP RS00045
gene id: 643648:SLIP_RS00045
uniprot id: D7CIF2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

643648:SLIP RS11085
gene id: 643648:SLIP_RS11085
uniprot id: D7CJM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

643648:SLIP RS03250
gene id: 643648:SLIP_RS03250
uniprot id: D7CL63
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

643648:SLIP RS00805
gene id: 643648:SLIP_RS00805
uniprot id: D7CJ69
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS11040
gene id: 643648:SLIP_RS11040
uniprot id: D7CJL5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

643648:SLIP RS07805
gene id: 643648:SLIP_RS07805
uniprot id: D7CNP7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS05420
gene id: 643648:SLIP_RS05420
uniprot id: D7CMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

643648:SLIP RS10935
gene id: 643648:SLIP_RS10935
uniprot id: D7CJJ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

643648:SLIP RS04320
gene id: 643648:SLIP_RS04320
uniprot id: D7CLS1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

643648:SLIP RS09210
gene id: 643648:SLIP_RS09210
uniprot id: D7CPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

643648:SLIP RS08605
gene id: 643648:SLIP_RS08605
uniprot id: D7CP49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS02400
gene id: 643648:SLIP_RS02400
uniprot id: D7CKP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

643648:SLIP RS03390
gene id: 643648:SLIP_RS03390
uniprot id: D7CL90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

643648:SLIP RS12150
gene id: 643648:SLIP_RS12150
uniprot id: D7CPB2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643648:SLIP RS02460
gene id: 643648:SLIP_RS02460
uniprot id: D7CKQ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

643648:SLIP RS10515
gene id: 643648:SLIP_RS10515
uniprot id: D7CIY9
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

643648:SLIP RS00110
gene id: 643648:SLIP_RS00110
uniprot id: D7CIF9
names: Similarity
messages: Belongs to the hemerythrin family.

643648:SLIP RS03015
gene id: 643648:SLIP_RS03015
uniprot id: D7CL18
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

643648:SLIP RS05285
gene id: 643648:SLIP_RS05285
uniprot id: D7CMB3
names: Similarity
messages: Belongs to the UPF0111 family.

643648:SLIP RS08480
gene id: 643648:SLIP_RS08480
uniprot id: D7CP26
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

643648:SLIP RS04015
gene id: 643648:SLIP_RS04015
uniprot id: D7CLL0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS03760
gene id: 643648:SLIP_RS03760
uniprot id: D7CLF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

643648:SLIP RS05445
gene id: 643648:SLIP_RS05445
uniprot id: D7CME3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

643648:SLIP RS03770
gene id: 643648:SLIP_RS03770
uniprot id: D7CLG0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643648:SLIP RS03285
gene id: 643648:SLIP_RS03285
uniprot id: D7CL70
names: Similarity
messages: Belongs to the EamA transporter family.

643648:SLIP RS05070
gene id: 643648:SLIP_RS05070
uniprot id: D7CM71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

643648:SLIP RS07640
gene id: 643648:SLIP_RS07640
uniprot id: D7CNM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

643648:SLIP RS01695
gene id: 643648:SLIP_RS01695
uniprot id: D7CK20
names: Similarity
messages: Belongs to the thioredoxin family.

643648:SLIP RS00470
gene id: 643648:SLIP_RS00470
uniprot id: D7CIM6
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04745
gene id: 643648:SLIP_RS04745
uniprot id: D7CM06
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643648:SLIP RS03965
gene id: 643648:SLIP_RS03965
uniprot id: D7CLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

643648:SLIP RS10980
gene id: 643648:SLIP_RS10980
uniprot id: D7CJK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

643648:SLIP RS07045
gene id: 643648:SLIP_RS07045
uniprot id: D7CNA0
names: Similarity
messages: Belongs to the Ahb/Nir family.

643648:SLIP RS03695
gene id: 643648:SLIP_RS03695
uniprot id: D7CLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

643648:SLIP RS02790
gene id: 643648:SLIP_RS02790
uniprot id: D7CKX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

643648:SLIP RS03365
gene id: 643648:SLIP_RS03365
uniprot id: D7CL86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

643648:SLIP RS11390
gene id: 643648:SLIP_RS11390
uniprot id: D7CJT0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

643648:SLIP RS07160
gene id: 643648:SLIP_RS07160
uniprot id: D7CNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

643648:SLIP RS06055
gene id: 643648:SLIP_RS06055
uniprot id: D7CMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS09285
gene id: 643648:SLIP_RS09285
uniprot id: D7CPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

643648:SLIP RS05230
gene id: 643648:SLIP_RS05230
uniprot id: D7CMA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

643648:SLIP RS01480
gene id: 643648:SLIP_RS01480
uniprot id: D7CJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

643648:SLIP RS10345
gene id: 643648:SLIP_RS10345
uniprot id: D7CIV8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS03790
gene id: 643648:SLIP_RS03790
uniprot id: D7CLG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS02110
gene id: 643648:SLIP_RS02110
uniprot id: D7CKI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

643648:SLIP RS09695
gene id: 643648:SLIP_RS09695
uniprot id: D7CPT2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643648:SLIP RS08215
gene id: 643648:SLIP_RS08215
uniprot id: D7CNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

643648:SLIP RS01550
gene id: 643648:SLIP_RS01550
uniprot id: D7CJY9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

643648:SLIP RS06795
gene id: 643648:SLIP_RS06795
uniprot id: D7CN52
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

643648:SLIP RS07040
gene id: 643648:SLIP_RS07040
uniprot id: D7CN99
names: Similarity
messages: Belongs to the Ahb/Nir family.

643648:SLIP RS08420
gene id: 643648:SLIP_RS08420
uniprot id: D7CP15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

643648:SLIP RS07195
gene id: 643648:SLIP_RS07195
uniprot id: D7CNC9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

643648:SLIP RS02870
gene id: 643648:SLIP_RS02870
uniprot id: D7CKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

643648:SLIP RS02435
gene id: 643648:SLIP_RS02435
uniprot id: D7CKQ1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS07415
gene id: 643648:SLIP_RS07415
uniprot id: D7CNH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

643648:SLIP RS10355
gene id: 643648:SLIP_RS10355
uniprot id: D7CIW0
names: Similarity
messages: Belongs to the universal stress protein A family.

643648:SLIP RS11560
gene id: 643648:SLIP_RS11560
uniprot id: D7CK83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS05150
gene id: 643648:SLIP_RS05150
uniprot id: D7CM87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

643648:SLIP RS11100
gene id: 643648:SLIP_RS11100
uniprot id: D7CJM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

643648:SLIP RS01600
gene id: 643648:SLIP_RS01600
uniprot id: D7CK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

643648:SLIP RS00570
gene id: 643648:SLIP_RS00570
uniprot id: D7CIP5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS11260
gene id: 643648:SLIP_RS11260
uniprot id: D7CJQ4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

643648:SLIP RS03835
gene id: 643648:SLIP_RS03835
uniprot id: D7CLH3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

643648:SLIP RS02910
gene id: 643648:SLIP_RS02910
uniprot id: D7CKZ7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

643648:SLIP RS01280
gene id: 643648:SLIP_RS01280
uniprot id: D7CJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS01230
gene id: 643648:SLIP_RS01230
uniprot id: D7CJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS04880
gene id: 643648:SLIP_RS04880
uniprot id: D7CM33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

643648:SLIP RS01875
gene id: 643648:SLIP_RS01875
uniprot id: D7CK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

643648:SLIP RS04685
gene id: 643648:SLIP_RS04685
uniprot id: D7CLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

643648:SLIP RS02090
gene id: 643648:SLIP_RS02090
uniprot id: D7CKH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS02120
gene id: 643648:SLIP_RS02120
uniprot id: D7CKI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS02215
gene id: 643648:SLIP_RS02215
uniprot id: D7CKK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS04865
gene id: 643648:SLIP_RS04865
uniprot id: D7CM30
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

643648:SLIP RS09140
gene id: 643648:SLIP_RS09140
uniprot id: D7CPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

643648:SLIP RS01700
gene id: 643648:SLIP_RS01700
uniprot id: D7CK21
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

643648:SLIP RS11220
gene id: 643648:SLIP_RS11220
uniprot id: D7CJP6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

643648:SLIP RS06905
gene id: 643648:SLIP_RS06905
uniprot id: D7CN74
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

643648:SLIP RS03385
gene id: 643648:SLIP_RS03385
uniprot id: D7CL89
names: Similarity
messages: Belongs to the transpeptidase family.

643648:SLIP RS11235
gene id: 643648:SLIP_RS11235
uniprot id: D7CJP9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

643648:SLIP RS02925
gene id: 643648:SLIP_RS02925
uniprot id: D7CL00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

643648:SLIP RS04950
gene id: 643648:SLIP_RS04950
uniprot id: D7CM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

643648:SLIP RS02990
gene id: 643648:SLIP_RS02990
uniprot id: D7CL13
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

643648:SLIP RS04560
gene id: 643648:SLIP_RS04560
uniprot id: D7CLW9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

643648:SLIP RS01520
gene id: 643648:SLIP_RS01520
uniprot id: D7CJY3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

643648:SLIP RS10565
gene id: 643648:SLIP_RS10565
uniprot id: D7CIZ9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

643648:SLIP RS04545
gene id: 643648:SLIP_RS04545
uniprot id: D7CLW8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

643648:SLIP RS07660
gene id: 643648:SLIP_RS07660
uniprot id: D7CNM5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

643648:SLIP RS03900
gene id: 643648:SLIP_RS03900
uniprot id: D7CLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

643648:SLIP RS04625
gene id: 643648:SLIP_RS04625
uniprot id: D7CLY2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

643648:SLIP RS06415
gene id: 643648:SLIP_RS06415
uniprot id: D7CMX9
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS02555
gene id: 643648:SLIP_RS02555
uniprot id: D7CKS4
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

643648:SLIP RS00635
gene id: 643648:SLIP_RS00635
uniprot id: D7CIQ8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

643648:SLIP RS04080
gene id: 643648:SLIP_RS04080
uniprot id: D7CLM3
names: Similarity
messages: Belongs to the UPF0237 family.

643648:SLIP RS11475
gene id: 643648:SLIP_RS11475
uniprot id: D7CK66
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS07520
gene id: 643648:SLIP_RS07520
uniprot id: D7CNJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

643648:SLIP RS02845
gene id: 643648:SLIP_RS02845
uniprot id: D7CKY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS02350
gene id: 643648:SLIP_RS02350
uniprot id: D7CKN4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS02375
gene id: 643648:SLIP_RS02375
uniprot id: D7CKN9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS09505
gene id: 643648:SLIP_RS09505
uniprot id: D7CPN5
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS07900
gene id: 643648:SLIP_RS07900
uniprot id: D7CNR8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

643648:SLIP RS06650
gene id: 643648:SLIP_RS06650
uniprot id: D7CN22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

643648:SLIP RS07300
gene id: 643648:SLIP_RS07300
uniprot id: D7CNF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

643648:SLIP RS03635
gene id: 643648:SLIP_RS03635
uniprot id: D7CLD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

643648:SLIP RS05715
gene id: 643648:SLIP_RS05715
uniprot id: D7CMJ4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS03680
gene id: 643648:SLIP_RS03680
uniprot id: D7CLE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643648:SLIP RS00550
gene id: 643648:SLIP_RS00550
uniprot id: D7CIP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

643648:SLIP RS11055
gene id: 643648:SLIP_RS11055
uniprot id: D7CJL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

643648:SLIP RS08940
gene id: 643648:SLIP_RS08940
uniprot id: D7CPB5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

643648:SLIP RS04790
gene id: 643648:SLIP_RS04790
uniprot id: D7CM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

643648:SLIP RS09320
gene id: 643648:SLIP_RS09320
uniprot id: D7CPJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

643648:SLIP RS06480
gene id: 643648:SLIP_RS06480
uniprot id: D7CMY9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS04425
gene id: 643648:SLIP_RS04425
uniprot id: D7CLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS02525
gene id: 643648:SLIP_RS02525
uniprot id: D7CKR8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

643648:SLIP RS08470
gene id: 643648:SLIP_RS08470
uniprot id: D7CP24
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

643648:SLIP RS01210
gene id: 643648:SLIP_RS01210
uniprot id: D7CJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS10880
gene id: 643648:SLIP_RS10880
uniprot id: D7CJI4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS03325
gene id: 643648:SLIP_RS03325
uniprot id: D7CL78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

643648:SLIP RS09160
gene id: 643648:SLIP_RS09160
uniprot id: D7CPG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

643648:SLIP RS10150
gene id: 643648:SLIP_RS10150
uniprot id: D7CIR7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

643648:SLIP RS01235
gene id: 643648:SLIP_RS01235
uniprot id: D7CJF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS05730
gene id: 643648:SLIP_RS05730
uniprot id: D7CMJ7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

643648:SLIP RS04615
gene id: 643648:SLIP_RS04615
uniprot id: D7CLY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

643648:SLIP RS08690
gene id: 643648:SLIP_RS08690
uniprot id: D7CP66
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

643648:SLIP RS05180
gene id: 643648:SLIP_RS05180
uniprot id: D7CM93
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

643648:SLIP RS02945
gene id: 643648:SLIP_RS02945
uniprot id: D7CL04
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

643648:SLIP RS02130
gene id: 643648:SLIP_RS02130
uniprot id: D7CKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

643648:SLIP RS10800
gene id: 643648:SLIP_RS10800
uniprot id: D7CJG8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS07645
gene id: 643648:SLIP_RS07645
uniprot id: D7CNM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

643648:SLIP RS09145
gene id: 643648:SLIP_RS09145
uniprot id: D7CPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

643648:SLIP RS04650
gene id: 643648:SLIP_RS04650
uniprot id: D7CLY7
names: Similarity
messages: Belongs to the DprA/Smf family.

643648:SLIP RS04760
gene id: 643648:SLIP_RS04760
uniprot id: D7CM09
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

643648:SLIP RS07605
gene id: 643648:SLIP_RS07605
uniprot id: D7CNL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

643648:SLIP RS09640
gene id: 643648:SLIP_RS09640
uniprot id: D7CPS1
names: Similarity
messages: Belongs to the Nth/MutY family.

643648:SLIP RS04360
gene id: 643648:SLIP_RS04360
uniprot id: D7CLS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS04675
gene id: 643648:SLIP_RS04675
uniprot id: D7CLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

643648:SLIP RS07175
gene id: 643648:SLIP_RS07175
uniprot id: D7CNC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

643648:SLIP RS09815
gene id: 643648:SLIP_RS09815
uniprot id: D7CPV3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

643648:SLIP RS07085
gene id: 643648:SLIP_RS07085
uniprot id: D7CNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

643648:SLIP RS10245
gene id: 643648:SLIP_RS10245
uniprot id: D7CIT8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

643648:SLIP RS01735
gene id: 643648:SLIP_RS01735
uniprot id: D7CK29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

643648:SLIP RS06635
gene id: 643648:SLIP_RS06635
uniprot id: D7CN19
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

643648:SLIP RS08090
gene id: 643648:SLIP_RS08090
uniprot id: D7CNV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643648:SLIP RS03995
gene id: 643648:SLIP_RS03995
uniprot id: D7CLK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

643648:SLIP RS11450
gene id: 643648:SLIP_RS11450
uniprot id: D7CK62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS05270
gene id: 643648:SLIP_RS05270
uniprot id: D7CMB0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

643648:SLIP RS11125
gene id: 643648:SLIP_RS11125
uniprot id: D7CJN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

643648:SLIP RS10420
gene id: 643648:SLIP_RS10420
uniprot id: D7CIX2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

643648:SLIP RS00580
gene id: 643648:SLIP_RS00580
uniprot id: D7CIP7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

643648:SLIP RS11275
gene id: 643648:SLIP_RS11275
uniprot id: D7CJQ7
names: Similarity
messages: Belongs to the CtsR family.

643648:SLIP RS10915
gene id: 643648:SLIP_RS10915
uniprot id: D7CJJ0
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS03860
gene id: 643648:SLIP_RS03860
uniprot id: D7CLH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

643648:SLIP RS09165
gene id: 643648:SLIP_RS09165
uniprot id: D7CPG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643648:SLIP RS11660
gene id: 643648:SLIP_RS11660
uniprot id: D7CKA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

643648:SLIP RS11555
gene id: 643648:SLIP_RS11555
uniprot id: D7CK82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

643648:SLIP RS07275
gene id: 643648:SLIP_RS07275
uniprot id: D7CNE5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

643648:SLIP RS08350
gene id: 643648:SLIP_RS08350
uniprot id: D7CP02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

643648:SLIP RS02835
gene id: 643648:SLIP_RS02835
uniprot id: D7CKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

643648:SLIP RS02535
gene id: 643648:SLIP_RS02535
uniprot id: D7CKS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

643648:SLIP RS06815
gene id: 643648:SLIP_RS06815
uniprot id: D7CN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

643648:SLIP RS08900
gene id: 643648:SLIP_RS08900
uniprot id: D7CPA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10920
gene id: 643648:SLIP_RS10920
uniprot id: D7CJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

643648:SLIP RS01430
gene id: 643648:SLIP_RS01430
uniprot id: D7CJW7
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

643648:SLIP RS01445
gene id: 643648:SLIP_RS01445
uniprot id: D7CJX0
names: Similarity
messages: Belongs to the GerABKA family.

643648:SLIP RS01115
gene id: 643648:SLIP_RS01115
uniprot id: D7CJC9
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS03155
gene id: 643648:SLIP_RS03155
uniprot id: D7CL44
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

643648:SLIP RS07425
gene id: 643648:SLIP_RS07425
uniprot id: D7CNH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS08165
gene id: 643648:SLIP_RS08165
uniprot id: D7CNW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

643648:SLIP RS07790
gene id: 643648:SLIP_RS07790
uniprot id: D7CNP4
names: Similarity
messages: Belongs to the glutamine synthetase family.

643648:SLIP RS07815
gene id: 643648:SLIP_RS07815
uniprot id: D7CNP9
names: Similarity
messages: Belongs to the P(II) protein family.

643648:SLIP RS07190
gene id: 643648:SLIP_RS07190
uniprot id: D7CNC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

643648:SLIP RS05145
gene id: 643648:SLIP_RS05145
uniprot id: D7CM86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

643648:SLIP RS11285
gene id: 643648:SLIP_RS11285
uniprot id: D7CJQ9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

643648:SLIP RS05560
gene id: 643648:SLIP_RS05560
uniprot id: D7CMG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

643648:SLIP RS04150
gene id: 643648:SLIP_RS04150
uniprot id: D7CLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

643648:SLIP RS01990
gene id: 643648:SLIP_RS01990
uniprot id: D7CKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

643648:SLIP RS02175
gene id: 643648:SLIP_RS02175
uniprot id: D7CKJ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

643648:SLIP RS02875
gene id: 643648:SLIP_RS02875
uniprot id: D7CKY9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

643648:SLIP RS03105
gene id: 643648:SLIP_RS03105
uniprot id: D7CL35
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643648:SLIP RS07290
gene id: 643648:SLIP_RS07290
uniprot id: D7CNE8
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

643648:SLIP RS10645
gene id: 643648:SLIP_RS10645
uniprot id: D7CJ14
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

643648:SLIP RS09860
gene id: 643648:SLIP_RS09860
uniprot id: D7CPW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS01415
gene id: 643648:SLIP_RS01415
uniprot id: D7CJW4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

643648:SLIP RS03685
gene id: 643648:SLIP_RS03685
uniprot id: D7CLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

643648:SLIP RS02765
gene id: 643648:SLIP_RS02765
uniprot id: D7CKW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

643648:SLIP RS08625
gene id: 643648:SLIP_RS08625
uniprot id: D7CP53
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

643648:SLIP RS10875
gene id: 643648:SLIP_RS10875
uniprot id: D7CJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

643648:SLIP RS02915
gene id: 643648:SLIP_RS02915
uniprot id: D7CKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

643648:SLIP RS00670
gene id: 643648:SLIP_RS00670
uniprot id: D7CJ41
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

643648:SLIP RS01880
gene id: 643648:SLIP_RS01880
uniprot id: D7CK58
names: Similarity
messages: Belongs to the peptidase A31 family.

643648:SLIP RS07615
gene id: 643648:SLIP_RS07615
uniprot id: D7CNL5
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

643648:SLIP RS03575
gene id: 643648:SLIP_RS03575
uniprot id: D7CLC1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643648:SLIP RS01215
gene id: 643648:SLIP_RS01215
uniprot id: D7CJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS08075
gene id: 643648:SLIP_RS08075
uniprot id: D7CNU9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

643648:SLIP RS11335
gene id: 643648:SLIP_RS11335
uniprot id: D7CJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

643648:SLIP RS06355
gene id: 643648:SLIP_RS06355
uniprot id: D7CMW9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

643648:SLIP RS08770
gene id: 643648:SLIP_RS08770
uniprot id: D7CP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS01145
gene id: 643648:SLIP_RS01145
uniprot id: D7CJD4
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS05785
gene id: 643648:SLIP_RS05785
uniprot id: D7CMK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

643648:SLIP RS01525
gene id: 643648:SLIP_RS01525
uniprot id: D7CJY4
names: Similarity
messages: Belongs to the peptidase S16 family.

643648:SLIP RS12135
gene id: 643648:SLIP_RS12135
uniprot id: D7CP19
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

643648:SLIP RS11550
gene id: 643648:SLIP_RS11550
uniprot id: D7CK81
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS01405
gene id: 643648:SLIP_RS01405
uniprot id: D7CJW2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

643648:SLIP RS02600
gene id: 643648:SLIP_RS02600
uniprot id: D7CKT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

643648:SLIP RS04220
gene id: 643648:SLIP_RS04220
uniprot id: D7CLQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS03300
gene id: 643648:SLIP_RS03300
uniprot id: D7CL73
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

643648:SLIP RS04915
gene id: 643648:SLIP_RS04915
uniprot id: D7CM40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

643648:SLIP RS04420
gene id: 643648:SLIP_RS04420
uniprot id: D7CLU2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

643648:SLIP RS05060
gene id: 643648:SLIP_RS05060
uniprot id: D7CM69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS01825
gene id: 643648:SLIP_RS01825
uniprot id: D7CK47
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS09185
gene id: 643648:SLIP_RS09185
uniprot id: D7CPH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643648:SLIP RS03200
gene id: 643648:SLIP_RS03200
uniprot id: D7CL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

643648:SLIP RS02745
gene id: 643648:SLIP_RS02745
uniprot id: D7CKW2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

643648:SLIP RS10930
gene id: 643648:SLIP_RS10930
uniprot id: D7CJJ3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

643648:SLIP RS07280
gene id: 643648:SLIP_RS07280
uniprot id: D7CNE6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

643648:SLIP RS03360
gene id: 643648:SLIP_RS03360
uniprot id: D7CL85
names: Similarity
messages: Belongs to the UPF0758 family.

643648:SLIP RS11755
gene id: 643648:SLIP_RS11755
uniprot id: D7CKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

643648:SLIP RS10165
gene id: 643648:SLIP_RS10165
uniprot id: D7CIS0
names: Similarity
messages: Belongs to the class-I fumarase family.

643648:SLIP RS01750
gene id: 643648:SLIP_RS01750
uniprot id: D7CK32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

643648:SLIP RS02720
gene id: 643648:SLIP_RS02720
uniprot id: D7CKV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

643648:SLIP RS03470
gene id: 643648:SLIP_RS03470
uniprot id: D7CLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

643648:SLIP RS11815
gene id: 643648:SLIP_RS11815
uniprot id: D7CKD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

643648:SLIP RS02355
gene id: 643648:SLIP_RS02355
uniprot id: D7CKN5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS06145
gene id: 643648:SLIP_RS06145
uniprot id: D7CMS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS07570
gene id: 643648:SLIP_RS07570
uniprot id: D7CNK6
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS06120
gene id: 643648:SLIP_RS06120
uniprot id: D7CMS4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS06750
gene id: 643648:SLIP_RS06750
uniprot id: D7CN43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643648:SLIP RS07725
gene id: 643648:SLIP_RS07725
uniprot id: D7CNN3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

643648:SLIP RS02440
gene id: 643648:SLIP_RS02440
uniprot id: D7CKQ2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

643648:SLIP RS01410
gene id: 643648:SLIP_RS01410
uniprot id: D7CJW3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

643648:SLIP RS02620
gene id: 643648:SLIP_RS02620
uniprot id: D7CKT7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

643648:SLIP RS06655
gene id: 643648:SLIP_RS06655
uniprot id: D7CN23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

643648:SLIP RS04190
gene id: 643648:SLIP_RS04190
uniprot id: D7CLP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS09220
gene id: 643648:SLIP_RS09220
uniprot id: D7CPH7
names: Similarity
messages: Belongs to the PGI/PMI family.

643648:SLIP RS08135
gene id: 643648:SLIP_RS08135
uniprot id: D7CNW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

643648:SLIP RS07305
gene id: 643648:SLIP_RS07305
uniprot id: D7CNF1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

643648:SLIP RS10325
gene id: 643648:SLIP_RS10325
uniprot id: D7CIV4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS01435
gene id: 643648:SLIP_RS01435
uniprot id: D7CJW8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

643648:SLIP RS10815
gene id: 643648:SLIP_RS10815
uniprot id: D7CJH1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

643648:SLIP RS02895
gene id: 643648:SLIP_RS02895
uniprot id: D7CKZ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643648:SLIP RS07470
gene id: 643648:SLIP_RS07470
uniprot id: D7CNI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

643648:SLIP RS08555
gene id: 643648:SLIP_RS08555
uniprot id: D7CP40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

643648:SLIP RS07165
gene id: 643648:SLIP_RS07165
uniprot id: D7CNC3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

643648:SLIP RS02480
gene id: 643648:SLIP_RS02480
uniprot id: D7CKQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643648:SLIP RS03640
gene id: 643648:SLIP_RS03640
uniprot id: D7CLD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

643648:SLIP RS05160
gene id: 643648:SLIP_RS05160
uniprot id: D7CM89
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

643648:SLIP RS07120
gene id: 643648:SLIP_RS07120
uniprot id: D7CNB4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

643648:SLIP RS06510
gene id: 643648:SLIP_RS06510
uniprot id: D7CMZ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS03975
gene id: 643648:SLIP_RS03975
uniprot id: D7CLK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

643648:SLIP RS01250
gene id: 643648:SLIP_RS01250
uniprot id: D7CJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643648:SLIP RS05505
gene id: 643648:SLIP_RS05505
uniprot id: D7CMF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS11240
gene id: 643648:SLIP_RS11240
uniprot id: D7CJQ0
names: Similarity
messages: Belongs to the ycf81 family.

643648:SLIP RS10170
gene id: 643648:SLIP_RS10170
uniprot id: D7CIS1
names: Similarity
messages: Belongs to the class-I fumarase family.

643648:SLIP RS02395
gene id: 643648:SLIP_RS02395
uniprot id: D7CKP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

643648:SLIP RS11635
gene id: 643648:SLIP_RS11635
uniprot id: D7CK97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

643648:SLIP RS03000
gene id: 643648:SLIP_RS03000
uniprot id: D7CL15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

643648:SLIP RS10960
gene id: 643648:SLIP_RS10960
uniprot id: D7CJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

643648:SLIP RS04470
gene id: 643648:SLIP_RS04470
uniprot id: D7CLV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

643648:SLIP RS10770
gene id: 643648:SLIP_RS10770
uniprot id: D7CJ39
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

643648:SLIP RS10535
gene id: 643648:SLIP_RS10535
uniprot id: D7CIZ3
names: Similarity
messages: Belongs to the P(II) protein family.

643648:SLIP RS01715
gene id: 643648:SLIP_RS01715
uniprot id: D7CK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643648:SLIP RS05290
gene id: 643648:SLIP_RS05290
uniprot id: D7CMB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

643648:SLIP RS11465
gene id: 643648:SLIP_RS11465
uniprot id: D7CK64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

643648:SLIP RS00305
gene id: 643648:SLIP_RS00305
uniprot id: D7CIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

643648:SLIP RS02230
gene id: 643648:SLIP_RS02230
uniprot id: D7CKK8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

643648:SLIP RS07385
gene id: 643648:SLIP_RS07385
uniprot id: D7CNG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643648:SLIP RS04340
gene id: 643648:SLIP_RS04340
uniprot id: D7CLS5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS04520
gene id: 643648:SLIP_RS04520
uniprot id: D7CLW2
names: Similarity
messages: Belongs to the UPF0102 family.

643648:SLIP RS07295
gene id: 643648:SLIP_RS07295
uniprot id: D7CNE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

643648:SLIP RS04690
gene id: 643648:SLIP_RS04690
uniprot id: D7CLZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

643648:SLIP RS04395
gene id: 643648:SLIP_RS04395
uniprot id: D7CLT6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

643648:SLIP RS08800
gene id: 643648:SLIP_RS08800
uniprot id: D7CP86
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

643648:SLIP RS11010
gene id: 643648:SLIP_RS11010
uniprot id: D7CJK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

643648:SLIP RS02325
gene id: 643648:SLIP_RS02325
uniprot id: D7CKM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS01080
gene id: 643648:SLIP_RS01080
uniprot id: D7CJC2
names: Subcellular Location Annotation
messages: Membrane

643648:SLIP RS04300
gene id: 643648:SLIP_RS04300
uniprot id: D7CLR7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

643648:SLIP RS08185
gene id: 643648:SLIP_RS08185
uniprot id: D7CNX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

643648:SLIP RS11045
gene id: 643648:SLIP_RS11045
uniprot id: D7CJL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS09555
gene id: 643648:SLIP_RS09555
uniprot id: D7CPQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS02665
gene id: 643648:SLIP_RS02665
uniprot id: D7CKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

643648:SLIP RS09310
gene id: 643648:SLIP_RS09310
uniprot id: D7CPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

643648:SLIP RS11290
gene id: 643648:SLIP_RS11290
uniprot id: D7CJR0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643648:SLIP RS11090
gene id: 643648:SLIP_RS11090
uniprot id: D7CJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

643648:SLIP RS03895
gene id: 643648:SLIP_RS03895
uniprot id: D7CLI5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS10490
gene id: 643648:SLIP_RS10490
uniprot id: D7CIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS06515
gene id: 643648:SLIP_RS06515
uniprot id: D7CMZ6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

643648:SLIP RS04975
gene id: 643648:SLIP_RS04975
uniprot id: D7CM52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

643648:SLIP RS04820
gene id: 643648:SLIP_RS04820
uniprot id: D7CM21
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

643648:SLIP RS04210
gene id: 643648:SLIP_RS04210
uniprot id: D7CLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

643648:SLIP RS03930
gene id: 643648:SLIP_RS03930
uniprot id: D7CLJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS02270
gene id: 643648:SLIP_RS02270
uniprot id: D7CKL7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

643648:SLIP RS08255
gene id: 643648:SLIP_RS08255
uniprot id: D7CNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643648:SLIP RS04380
gene id: 643648:SLIP_RS04380
uniprot id: D7CLT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

643648:SLIP RS02900
gene id: 643648:SLIP_RS02900
uniprot id: D7CKZ5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

643648:SLIP RS08205
gene id: 643648:SLIP_RS08205
uniprot id: D7CNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

643648:SLIP RS00700
gene id: 643648:SLIP_RS00700
uniprot id: D7CJ47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

643648:SLIP RS01855
gene id: 643648:SLIP_RS01855
uniprot id: D7CK53
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

643648:SLIP RS09515
gene id: 643648:SLIP_RS09515
uniprot id: D7CPP4
names: Similarity
messages: Belongs to the GSP E family.

643648:SLIP RS04060
gene id: 643648:SLIP_RS04060
uniprot id: D7CLL9
names: Similarity
messages: Belongs to the UPF0235 family.

643648:SLIP RS06645
gene id: 643648:SLIP_RS06645
uniprot id: D7CN21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

643648:SLIP RS11385
gene id: 643648:SLIP_RS11385
uniprot id: D7CJS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS03875
gene id: 643648:SLIP_RS03875
uniprot id: D7CLI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

643648:SLIP RS02950
gene id: 643648:SLIP_RS02950
uniprot id: D7CL05
names: Similarity
messages: Belongs to the GARS family.

643648:SLIP RS06385
gene id: 643648:SLIP_RS06385
uniprot id: D7CMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

643648:SLIP RS08530
gene id: 643648:SLIP_RS08530
uniprot id: D7CP35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

643648:SLIP RS10925
gene id: 643648:SLIP_RS10925
uniprot id: D7CJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

643648:SLIP RS04405
gene id: 643648:SLIP_RS04405
uniprot id: D7CLT9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

643648:SLIP RS04715
gene id: 643648:SLIP_RS04715
uniprot id: D7CM00
names: Subcellular Location Annotation
messages: Cytoplasm

643648:SLIP RS04805
gene id: 643648:SLIP_RS04805
uniprot id: D7CM18
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

643648:SLIP RS11050
gene id: 643648:SLIP_RS11050
uniprot id: D7CJL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

643648:SLIP RS09780
gene id: 643648:SLIP_RS09780
uniprot id: D7CPU8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

643648:SLIP RS10985
gene id: 643648:SLIP_RS10985
uniprot id: D7CJK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

643648:SLIP RS02935
gene id: 643648:SLIP_RS02935
uniprot id: D7CL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

643648:SLIP RS04970
gene id: 643648:SLIP_RS04970
uniprot id: D7CM51
names: Similarity
messages: Belongs to the ribF family.

643648:SLIP RS02905
gene id: 643648:SLIP_RS02905
uniprot id: D7CKZ6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

643648:SLIP RS07835
gene id: 643648:SLIP_RS07835
uniprot id: D7CNQ4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS00890
gene id: 643648:SLIP_RS00890
uniprot id: D7CJ87
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS10695
gene id: 643648:SLIP_RS10695
uniprot id: D7CJ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

643648:SLIP RS04310
gene id: 643648:SLIP_RS04310
uniprot id: D7CLR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643648:SLIP RS02245
gene id: 643648:SLIP_RS02245
uniprot id: D7CKL1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

643648:SLIP RS02615
gene id: 643648:SLIP_RS02615
uniprot id: D7CKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

643648:SLIP RS04235
gene id: 643648:SLIP_RS04235
uniprot id: D7CLQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

643648:SLIP RS01895
gene id: 643648:SLIP_RS01895
uniprot id: D7CKE0
names: Similarity
messages: Belongs to the HypD family.

643648:SLIP RS02515
gene id: 643648:SLIP_RS02515
uniprot id: D7CKR6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643648:SLIP RS07745
gene id: 643648:SLIP_RS07745
uniprot id: D7CNN7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643648:SLIP RS08685
gene id: 643648:SLIP_RS08685
uniprot id: D7CP65
names: Similarity
messages: Belongs to the Fur family.

643648:SLIP RS05495
gene id: 643648:SLIP_RS05495
uniprot id: D7CMF4
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643648:SLIP RS04930
gene id: 643648:SLIP_RS04930
uniprot id: D7CM43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

643648:SLIP RS09315
gene id: 643648:SLIP_RS09315
uniprot id: D7CPJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

643648:SLIP RS11835
gene id: 643648:SLIP_RS11835
uniprot id: D7CKD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

643648:SLIP RS00915
gene id: 643648:SLIP_RS00915
uniprot id: D7CJ92
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643648:SLIP RS06740
gene id: 643648:SLIP_RS06740
uniprot id: D7CN40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643648:SLIP RS04920
gene id: 643648:SLIP_RS04920
uniprot id: D7CM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

643648:SLIP RS09855
gene id: 643648:SLIP_RS09855
uniprot id: D7CPW1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS06785
gene id: 643648:SLIP_RS06785
uniprot id: D7CN50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

643648:SLIP RS01850
gene id: 643648:SLIP_RS01850
uniprot id: D7CK52
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

643648:SLIP RS04705
gene id: 643648:SLIP_RS04705
uniprot id: D7CLZ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

643648:SLIP RS02250
gene id: 643648:SLIP_RS02250
uniprot id: D7CKL3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643648:SLIP RS04730
gene id: 643648:SLIP_RS04730
uniprot id: D7CM03
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

643648:SLIP RS08055
gene id: 643648:SLIP_RS08055
uniprot id: D7CNU5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

643648:SLIP RS11120
gene id: 643648:SLIP_RS11120
uniprot id: D7CJN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643648:SLIP RS11355
gene id: 643648:SLIP_RS11355
uniprot id: D7CJS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643648:SLIP RS00665
gene id: 643648:SLIP_RS00665
uniprot id: D7CJ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

643648:SLIP RS11360
gene id: 643648:SLIP_RS11360
uniprot id: D7CJS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

643648:SLIP RS08950
gene id: 643648:SLIP_RS08950
uniprot id: D7CPB7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

643648:SLIP RS04925
gene id: 643648:SLIP_RS04925
uniprot id: D7CM42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

643648:SLIP RS11340
gene id: 643648:SLIP_RS11340
uniprot id: D7CJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

643648:SLIP RS03785
gene id: 643648:SLIP_RS03785
uniprot id: D7CLG3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

643648:SLIP RS10955
gene id: 643648:SLIP_RS10955
uniprot id: D7CJJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

643648:SLIP RS07715
gene id: 643648:SLIP_RS07715
uniprot id: D7CNN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643648:SLIP RS00275
gene id: 643648:SLIP_RS00275
uniprot id: D7CII8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

643648:SLIP RS04255
gene id: 643648:SLIP_RS04255
uniprot id: D7CLQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

643648:SLIP RS06585
gene id: 643648:SLIP_RS06585
uniprot id: D7CN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

643648:SLIP RS08195
gene id: 643648:SLIP_RS08195
uniprot id: D7CNX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

643648:SLIP RS02240
gene id: 643648:SLIP_RS02240
uniprot id: D7CKL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643648:SLIP RS09850
gene id: 643648:SLIP_RS09850
uniprot id: D7CPW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.